Aliases for INPP4B Gene
External Ids for INPP4B Gene
Previous GeneCards Identifiers for INPP4B Gene
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]
GeneCards Summary for INPP4B Gene
INPP4B (Inositol Polyphosphate-4-Phosphatase Type II B) is a Protein Coding gene. Diseases associated with INPP4B include Vulva Adenocarcinoma. Among its related pathways are Inositol phosphate metabolism (REACTOME) and PI3K / Akt Signaling. GO annotations related to this gene include lipid binding and phosphatidylinositol trisphosphate phosphatase activity. An important paralog of this gene is INPP4A.
UniProtKB/Swiss-Prot for INPP4B Gene
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate.