Free for academic non-profit institutions. Other users need a Commercial license

Aliases for INO80D Gene

Aliases for INO80D Gene

  • INO80 Complex Subunit D 2 3

External Ids for INO80D Gene

Summaries for INO80D Gene

GeneCards Summary for INO80D Gene

INO80D (INO80 Complex Subunit D) is a Protein Coding gene. Among its related pathways are Gastric cancer network 1. An important paralog of this gene is KANSL2.

UniProtKB/Swiss-Prot for INO80D Gene

  • Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INO80D Gene

Genomics for INO80D Gene

Genomic Location for INO80D Gene

Start:
205,993,721 bp from pter
End:
206,086,303 bp from pter
Size:
92,583 bases
Orientation:
Minus strand

Genomic View for INO80D Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for INO80D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INO80D Gene

Regulatory Elements for INO80D Gene

Proteins for INO80D Gene

  • Protein details for INO80D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q53TQ3-IN80D_HUMAN
    Recommended name:
    INO80 complex subunit D
    Protein Accession:
    Q53TQ3
    Secondary Accessions:
    • B3KU68
    • B9EG77
    • Q6PJC6
    • Q6PJU1
    • Q6PKA1
    • Q9NXD5

    Protein attributes for INO80D Gene

    Size:
    878 amino acids
    Molecular mass:
    98174 Da
    Quaternary structure:
    • Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.
    SequenceCaution:
    • Sequence=AAH04193.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAH11687.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH11687.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAH17290.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAX93069.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAA91079.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA91079.1; Type=Frameshift; Positions=513; Evidence={ECO:0000305};

    Alternative splice isoforms for INO80D Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for INO80D Gene

Proteomics data for INO80D Gene at MOPED

Post-translational modifications for INO80D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for INO80D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for INO80D Gene

Domains for INO80D Gene

Gene Families for INO80D Gene

HGNC:
  • INO80 :INO80 complex subunits

Protein Domains for INO80D Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

IN80D_HUMAN
Family:
  • Belongs to the INO80D family.:
    • Q53TQ3
genes like me logo Genes that share domains with INO80D: view

Function for INO80D Gene

Molecular function for INO80D Gene

UniProtKB/Swiss-Prot Function: Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for INO80D Gene

Localization for INO80D Gene

Subcellular locations from UniProtKB/Swiss-Prot for INO80D Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for INO80D Gene COMPARTMENTS Subcellular localization image for INO80D gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for INO80D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with INO80D: view

Pathways for INO80D Gene

SuperPathways for INO80D Gene

Superpath Contained pathways
1 Gastric cancer network 1
genes like me logo Genes that share pathways with INO80D: view

Pathways by source for INO80D Gene

1 BioSystems pathway for INO80D Gene

Gene Ontology (GO) - Biological Process for INO80D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006281 DNA repair IEA --
GO:0006310 DNA recombination IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with INO80D: view

Transcripts for INO80D Gene

Unigene Clusters for INO80D Gene

INO80 complex subunit D:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for INO80D Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1:
SP2:
SP3: -

Relevant External Links for INO80D Gene

GeneLoc Exon Structure for
INO80D
ECgene alternative splicing isoforms for
INO80D

Expression for INO80D Gene

mRNA expression in normal human tissues for INO80D Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for INO80D Gene

SOURCE GeneReport for Unigene cluster for INO80D Gene Hs.445036

genes like me logo Genes that share expressions with INO80D: view

Orthologs for INO80D Gene

This gene was present in the common ancestor of animals.

Orthologs for INO80D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia INO80D 36
  • 99.77 (n)
  • 99.9 (a)
INO80D 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia INO80D 36
  • 92.91 (n)
  • 95.71 (a)
INO80D 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia INO80D 36
  • 95.39 (n)
  • 96.98 (a)
INO80D 37
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ino80d 36
  • 90.7 (n)
  • 94.52 (a)
Ino80d 16
Ino80d 37
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia INO80D 37
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia INO80D 37
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ino80d 36
  • 91.48 (n)
  • 95.59 (a)
chicken
(Gallus gallus)
Aves INO80D 36
  • 87.75 (n)
  • 91.81 (a)
INO80D 37
  • 90 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia INO80D 37
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ino80d 36
  • 74.31 (n)
  • 76.47 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.13218 36
ino80da 37
  • 57 (a)
OneToMany
ino80db 37
  • 49 (a)
OneToMany
LOC555228 36
  • 61.31 (n)
  • 63.63 (a)
fruit fly
(Drosophila melanogaster)
Insecta dgt1 37
  • 13 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 15 (a)
OneToMany
Species with no ortholog for INO80D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for INO80D Gene

ENSEMBL:
Gene Tree for INO80D (if available)
TreeFam:
Gene Tree for INO80D (if available)

Paralogs for INO80D Gene

Paralogs for INO80D Gene

genes like me logo Genes that share paralogs with INO80D: view

Variants for INO80D Gene

Sequence variations from dbSNP and Humsavar for INO80D Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs713106 -- 205,997,280(+) CAATT(C/T)TCCTA utr-variant-3-prime
rs817990 -- 206,009,277(+) CACTT(A/G)GCCTG intron-variant
rs817991 -- 206,009,615(+) CTGGC(A/G)GGCAT reference, synonymous-codon
rs817992 -- 206,011,535(+) TATTC(A/G)CTCCC intron-variant
rs817993 -- 206,012,202(+) aaaat(A/G)cagaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for INO80D Gene

Variant ID Type Subtype PubMed ID
nsv875733 CNV Gain 21882294
nsv508196 CNV Loss 20534489
esv2665558 CNV Deletion 23128226

Relevant External Links for INO80D Gene

HapMap Linkage Disequilibrium report
INO80D
Human Gene Mutation Database (HGMD)
INO80D

Disorders for INO80D Gene

Relevant External Links for INO80D

Genetic Association Database (GAD)
INO80D
genes like me logo Genes that share disorders with INO80D: view

No data available for UniProtKB/Swiss-Prot for INO80D Gene

Publications for INO80D Gene

  1. A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. (PMID: 16230350) Jin J. … Conaway J.W. (J. Biol. Chem. 2005) 2 3 4
  2. Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. (PMID: 21303910) Chen L. … Conaway R.C. (J. Biol. Chem. 2011) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for INO80D Gene

Sources for INO80D Gene

Back to Top

Content