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INO80D Gene

protein-coding   GIFtS: 47
GCID: GC02M206858

INO80 Complex Subunit D

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
INO80 Complex Subunit D1 2

External Ids:    HGNC: 259971   Entrez Gene: 548912   Ensembl: ENSG000001149337   UniProtKB: Q53TQ33   

Export aliases for INO80D gene to outside databases

Previous GC identifers: GC02M206566 GC02M198706


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for INO80D Gene:
INO80D (INO80 complex subunit D) is a protein-coding gene. An important paralog of this gene is KANSL2.

UniProtKB/Swiss-Prot: IN80D_HUMAN, Q53TQ3
Function: Putative regulatory component of the chromatin remodeling INO80 complex which is involved in
transcriptional regulation, DNA replication and probably DNA repair




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the INO80D gene promoter:
         AML1a   Pax-5   Cdc5   NF-kappaB   Egr-4   COMP1   NF-kappaB2   ARP-1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): INO80D promoter sequence
   Search Chromatin IP Primers for INO80D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat INO80D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.3   Ensembl cytogenetic band:  2q33.3   HGNC cytogenetic band: 2q33.3

INO80D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
INO80D gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M206858:  view genomic region     (about GC identifiers)

Start:
206,858,445 bp from pter      End:
206,951,027 bp from pter
Size:
92,583 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IN80D_HUMAN, Q53TQ3 (See protein sequence)
Recommended Name: INO80 complex subunit D  
Size: 878 amino acids; 98174 Da
Subunit: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated
with the N-terminus of INO80
Sequence caution: Sequence=AAH04193.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAH11687.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH11687.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Sequence=AAH17290.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Sequence=AAX93069.1; Type=Erroneous gene model prediction; Sequence=BAA91079.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=BAA91079.1; Type=Frameshift; Positions=513;
Secondary accessions: B3KU68 B9EG77 Q6PJC6 Q6PJU1 Q6PKA1 Q9NXD5
Alternative splicing: 2 isoforms:  Q53TQ3-1   Q53TQ3-2   

Explore the universe of human proteins at neXtProt for INO80D: NX_Q53TQ3

Explore proteomics data for INO80D at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See INO80D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060229.3  
    ENSEMBL proteins: 
     ENSP00000384198   ENSP00000402369   ENSP00000409031  

    INO80D Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for INO80D

     
    Search eBioscience for Proteins for INO80D 

     
    Search antibodies-online for proteins for INO80D 

     
    Search antibodies-online for peptides for INO80D

    INO80D Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for INO80D
    Novus Biologicals INO80D Antibody
    Abcam antibodies for INO80D
    Cloud-Clone Corp. Antibodies for INO80D
    ThermoFisher Antibodies for INO80D
    Search antibodies-online for antibodies for INO80D 

    INO80D Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for INO80D
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for INO80D
    Cloud-Clone Corp. CLIAs for INO80D
    Search eBioscience for ELISAs for INO80D 
    antibodies-online kits for INO80D (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    INO80: INO80 complex subunits

    1 InterPro protein domain:
     IPR025927 Potential_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q53TQ3

    ProtoNet protein and cluster: Q53TQ3

    UniProtKB/Swiss-Prot: IN80D_HUMAN, Q53TQ3
    Similarity: Belongs to the INO80D family


    Find genes that share domains with INO80D           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IN80D_HUMAN, Q53TQ3
    Function: Putative regulatory component of the chromatin remodeling INO80 complex which is involved in
    transcriptional regulation, DNA replication and probably DNA repair

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for INO80D

    miRNA
    Products:
        
    miRTarBase miRNAs that target INO80D:
    hsa-mir-128-3p (MIRT045886), hsa-mir-342-3p (MIRT043718), hsa-mir-1229-3p (MIRT036300), hsa-mir-27a-3p (MIRT028742), hsa-mir-320a (MIRT044540), hsa-mir-101-3p (MIRT027306), hsa-mir-16-5p (MIRT051164)

    Block miRNA regulation of human, mouse, rat INO80D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate INO80D (see all 278):
    hsa-miR-194* hsa-miR-579 hsa-miR-576-3p hsa-miR-361-5p hsa-miR-193a-3p hsa-miR-1260b hsa-miR-605 hsa-miR-3916
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for INO80D
    Predesigned siRNA for gene silencing in human, mouse, rat INO80D

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for INO80D

    Clone
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    OriGene clones in human, mouse for INO80D (see all 6)
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    GenScript: all cDNA clones in your preferred vector: INO80D (NM_017759)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for INO80D
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INO80D
    Addgene plasmids for INO80D 

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for INO80D 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INO80D


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IN80D_HUMAN, Q53TQ3: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with INO80D           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for INO80D About    
    See pathways by source

    SuperPathContained pathways About
    1Gastric cancer network 1
    Gastric cancer network 1


    1 BioSystems Pathway for INO80D
        Gastric cancer network 1


        Pathway & Disease-focused RT2 Profiler PCR Array including INO80D: 
              Polycomb & Trithorax Complexes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for INO80D

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for INO80D (Q53TQ33 ENSP000003841984) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTR5Q9H9F93, ENSP000002439034I2D: score=2 STRING: ENSP00000243903
    ACTR8Q9H9813, ENSP000003368424I2D: score=2 STRING: ENSP00000336842
    INO80EQ8NBZ03, ENSP000003039774I2D: score=2 STRING: ENSP00000303977
    MCRS1Q96EZ83, ENSP000003496404I2D: score=2 STRING: ENSP00000349640
    RUVBL2Q9Y2303, ENSP000002214134I2D: score=2 STRING: ENSP00000221413
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair IEA--
    GO:0006310DNA recombination IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with INO80D           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for INO80D (IN80D)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for INO80D gene: 
    NM_017759.4  

    Unigene Cluster for INO80D:

    INO80 complex subunit D
    Hs.445036  [show with all ESTs]
    Unigene Representative Sequence: NM_017759
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000403263(uc002vaz.4) ENST00000424117 ENST00000414320
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat INO80D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate INO80D (see all 278):
    hsa-miR-194* hsa-miR-579 hsa-miR-576-3p hsa-miR-361-5p hsa-miR-193a-3p hsa-miR-1260b hsa-miR-605 hsa-miR-3916
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for INO80D
    Predesigned siRNA for gene silencing in human, mouse, rat INO80D
    Clone
    Products:
         
    OriGene clones in human, mouse for INO80D (see all 6)
    OriGene ORF clones in mouse, rat for INO80D
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: INO80D (NM_017759)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for INO80D
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INO80D
    Addgene plasmids for INO80D 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for INO80D
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat INO80D
      QuantiTect SYBR Green Assays in human, mouse, rat INO80D
      QuantiFast Probe-based Assays in human, mouse, rat INO80D

    Additional mRNA sequence: 

    AK000316.1 AK096585.1 AK225339.1 BC004193.2 BC011687.2 BC017290.2 BC136278.1 CR933609.1 
    JF736506.1 

    13 DOTS entries:

    DT.446363  DT.40310023  DT.91878686  DT.86836880  DT.100033487  DT.40287535  DT.95261974  DT.439714 
    DT.91834091  DT.95150658  DT.91656881  DT.91695253  DT.91903267 

    Selected AceView cDNA sequences (see all 26):

    BC017290 BC004193 AW504943 BC011687 AA258832 BF308518 AI954752 NM_017759 
    AI817469 AK096585 AW847713 AK000316 AW847718 BU661283 AW847921 AA258831 
    AW847851 BE061066 BE297384 BF911427 BF327621 BG005151 BF991512 BI055433 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for INO80D    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                                        
    SP2:                                                                        
    SP3:              -                                                         


    ECgene alternative splicing isoforms for INO80D

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    INO80D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    INO80D Expression
    About this image

    INO80D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    INO80D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.445036
        Pathway & Disease-focused RT2 Profiler PCR Array including INO80D: 
              Polycomb & Trithorax Complexes in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for INO80D
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat INO80D
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INO80D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for INO80D gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ino80d1 , 5 INO80 complex subunit D1, 5 90.7(n)1
    94.52(a)1
      1 (31.89 cM)5
    2271951  NM_001114609.11  NP_001108081.11 
     629584185 
    chicken
    (Gallus gallus)
    Aves INO80D1 INO80 complex subunit D 87.75(n)
    91.81(a)
      424103  XM_421957.4  XP_421957.4 
    lizard
    (Anolis carolinensis)
    Reptilia INO80D6
    INO80 complex subunit D
    87(a)
    1 ↔ 1
    GL343208.1(703542-723697)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ032105.12   -- 81.54(n)    BJ032105.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.132182 Transcribed sequences 80(n)    BI877332.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta dgt16
    dim gamma-tubulin 1
    13(a)
    1 → many
    3R(25680417-25683191)


    ENSEMBL Gene Tree for INO80D (if available)
    TreeFam Gene Tree for INO80D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for INO80D gene
    KANSL22  

    Find genes that share paralogs with INO80D           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for INO80D (see all 1598)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1848922871,2
    --206858037(+) TCTTCA/GAGTTT 1 -- ds50010--------
    rs1883888841,2
    --206858103(+) AACTAC/TGAAAA 1 -- ds50010--------
    rs1120821861,2
    C--206858172(+) TATAGC/TATATA 1 -- ds50012Minor allele frequency- T:0.04WA 120
    rs1808240811,2
    --206858260(+) TCCACA/GGCTAT 1 -- ds50010--------
    rs1858516441,2
    --206858386(+) ACTTAC/TCCTGG 1 -- ds50010--------
    rs1394022361,2
    --206858904(+) TGGCTC/TCTAAC 1 -- ut310--------
    rs1898641861,2
    C--206858941(+) CCACTA/GTGAAC 1 -- ut310--------
    rs1811383721,2
    --206858970(+) TTGTCA/CGTTTG 1 -- ut310--------
    rs1860345171,2
    --206859042(+) CATACC/TTGGGT 1 -- ut310--------
    rs1499467991,2
    --206859090(+) GAGAAC/TCGCTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for INO80D (206858445 - 206951027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for INO80D:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665558CNV Deletion23128226
    nsv508196CNV Loss20534489
    nsv875733CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing INO80D
    DNA2.0 Custom Variant and Variant Library Synthesis for INO80D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with INO80D           About GenesLikeMe

    Genetic Association Database (GAD): INO80D

    Export disorders for INO80D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for INO80D gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with INO80D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. (PubMed id 16230350)1, 2, 3 Jin J.... Conaway J.W. (J. Biol. Chem. 2005)
    2. Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. (PubMed id 21303910)1, 2 Chen L.... Conaway R.C. (J. Biol. Chem. 2011)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Common body mass index-associated variants confer risk of extreme obesity. (PubMed id 19553259)1 Cotsapas C....Daly M.J. (Hum. Mol. Genet. 2009)
    5. Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. (PubMed id 18922472)2 Yao T.... Conaway J.W. (Mol. Cell 2008)
    6. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PubMed id 17903306)4 Newton-Cheh C....Larson M.G. (BMC Med. Genet. 2007)
    7. YY1 functions with INO80 to activate transcription. (PubMed id 17721549)1 Cai Y.... Conaway J.W. (Nat. Struct. Mol. Biol. 2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54891 HGNC: 25997 AceView: FLJ20309 Ensembl:ENSG00000114933 euGenes: HUgn54891
    ECgene: INO80D H-InvDB: INO80D

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for INO80D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for INO80D gene:
    Search GeneIP for patents involving INO80D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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