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Aliases for INO80B-WBP1 Gene

Subcategory (RNA class) for INO80B-WBP1 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for INO80B-WBP1 Gene

  • INO80B-WBP1 Readthrough (NMD Candidate) 2 3 5

External Ids for INO80B-WBP1 Gene

Previous GeneCards Identifiers for INO80B-WBP1 Gene

  • GC02U902385
  • GC02P074683

Summaries for INO80B-WBP1 Gene

Entrez Gene Summary for INO80B-WBP1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring INO80B (INO80 complex subunit B) and WBP1 (WW domain-binding protein 1) genes on chromosome 2. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for INO80B-WBP1 Gene

INO80B-WBP1 (INO80B-WBP1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is INO80B.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INO80B-WBP1 Gene

Genomics for INO80B-WBP1 Gene

Regulatory Elements for INO80B-WBP1 Gene

Enhancers for INO80B-WBP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G074454 1.2 ENCODE 0.7 +2.1 2085 5.4 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 LBX2 WBP1 ENSG00000270571 INO80B INO80B-WBP1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around INO80B-WBP1 on UCSC Golden Path with GeneCards custom track

Promoters for INO80B-WBP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000119165 -22 1200 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC

Genomic Location for INO80B-WBP1 Gene

Chromosome:
2
Start:
74,455,023 bp from pter
End:
74,460,891 bp from pter
Size:
5,869 bases
Orientation:
Plus strand

Genomic View for INO80B-WBP1 Gene

Genes around INO80B-WBP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INO80B-WBP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INO80B-WBP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INO80B-WBP1 Gene

Proteins for INO80B-WBP1 Gene

  • Protein details for INO80B-WBP1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8WCL7
    Recommended name:
    INO80B-WBP1 readthrough (NMD candidate)
    Protein Accession:
    F8WCL7

    Protein attributes for INO80B-WBP1 Gene

    Size:
    263 amino acids
    Molecular mass:
    29262 Da
    Quaternary structure:
    No Data Available
  • Protein details for INO80B-WBP1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    J3KQ70
    Recommended name:
    HCG2039827, isoform CRA_e
    Protein Accession:
    J3KQ70

    Protein attributes for INO80B-WBP1 Gene

    Size:
    363 amino acids
    Molecular mass:
    39432 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INO80B-WBP1 Gene

Post-translational modifications for INO80B-WBP1 Gene

No Post-translational modifications

Other Protein References for INO80B-WBP1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for INO80B-WBP1 Gene

Domains & Families for INO80B-WBP1 Gene

Protein Domains for INO80B-WBP1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with INO80B-WBP1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for INO80B-WBP1 Gene

Function for INO80B-WBP1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INO80B-WBP1 Gene

Localization for INO80B-WBP1 Gene

Gene Ontology (GO) - Cellular Components for INO80B-WBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031011 Ino80 complex IEA --
genes like me logo Genes that share ontologies with INO80B-WBP1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for INO80B-WBP1 Gene

Pathways & Interactions for INO80B-WBP1 Gene

SuperPathways for INO80B-WBP1 Gene

No Data Available

Interacting Proteins for INO80B-WBP1 Gene

Gene Ontology (GO) - Biological Process for INO80B-WBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with INO80B-WBP1: view

No data available for Pathways by source and SIGNOR curated interactions for INO80B-WBP1 Gene

Drugs & Compounds for INO80B-WBP1 Gene

No Compound Related Data Available

Transcripts for INO80B-WBP1 Gene

mRNA/cDNA for INO80B-WBP1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for INO80B-WBP1 Gene

No ASD Table

Relevant External Links for INO80B-WBP1 Gene

GeneLoc Exon Structure for
INO80B-WBP1
ECgene alternative splicing isoforms for
INO80B-WBP1

Expression for INO80B-WBP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for INO80B-WBP1 Gene

Protein differential expression in normal tissues from HIPED for INO80B-WBP1 Gene

This gene is overexpressed in Liver (40.8), CD8 Tcells (9.9), and Lung (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for INO80B-WBP1 Gene



Protein tissue co-expression partners for INO80B-WBP1 Gene

genes like me logo Genes that share expression patterns with INO80B-WBP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INO80B-WBP1 Gene

Orthologs for INO80B-WBP1 Gene

Evolution for INO80B-WBP1 Gene

ENSEMBL:
Gene Tree for INO80B-WBP1 (if available)
TreeFam:
Gene Tree for INO80B-WBP1 (if available)

No data available for Orthologs for INO80B-WBP1 Gene

Paralogs for INO80B-WBP1 Gene

Paralogs for INO80B-WBP1 Gene

genes like me logo Genes that share paralogs with INO80B-WBP1: view

Variants for INO80B-WBP1 Gene

Sequence variations from dbSNP and Humsavar for INO80B-WBP1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs368859958 Uncertain significance 74,461,355(+) ATCGC(A/C/G)GTCAC downstream-variant-500B, reference, missense
rs886056337 Uncertain significance 74,461,110(-) TGAAT(A/G)TGAAT downstream-variant-500B, utr-variant-3-prime
rs1000432692 -- 74,455,148(+) CACCT(C/T)TGGGG nc-transcript-variant, reference, missense
rs1000448439 -- 74,461,214(+) CAGAA(C/G)CCTTT downstream-variant-500B, utr-variant-3-prime
rs1001347317 -- 74,457,113(+) TAAAG(C/T)TAAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for INO80B-WBP1 Gene

Variant ID Type Subtype PubMed ID
esv2759061 CNV loss 17122850
nsv458185 CNV loss 19166990
nsv515851 CNV loss 19592680
nsv582214 CNV loss 21841781

Relevant External Links for INO80B-WBP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INO80B-WBP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for INO80B-WBP1 Gene

Disorders for INO80B-WBP1 Gene

Relevant External Links for INO80B-WBP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
INO80B-WBP1

No disorders were found for INO80B-WBP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for INO80B-WBP1 Gene

Publications for INO80B-WBP1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  3. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3 64

Products for INO80B-WBP1 Gene

Sources for INO80B-WBP1 Gene

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