Free for academic non-profit institutions. Other users need a Commercial license

Aliases for INO80B-WBP1 Gene

Subcategory (RNA class) for INO80B-WBP1 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for INO80B-WBP1 Gene

  • INO80B-WBP1 Readthrough (NMD Candidate) 2 3 5

External Ids for INO80B-WBP1 Gene

Previous GeneCards Identifiers for INO80B-WBP1 Gene

  • GC02U902385
  • GC02P074683

Summaries for INO80B-WBP1 Gene

Entrez Gene Summary for INO80B-WBP1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring INO80B (INO80 complex subunit B) and WBP1 (WW domain-binding protein 1) genes on chromosome 2. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for INO80B-WBP1 Gene

INO80B-WBP1 (INO80B-WBP1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is INO80B.

Additional gene information for INO80B-WBP1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INO80B-WBP1 Gene

Genomics for INO80B-WBP1 Gene

GeneHancer (GH) Regulatory Elements for INO80B-WBP1 Gene

Promoters and enhancers for INO80B-WBP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I074454 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.8 +2.1 2085 5.4 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 WBP1 INO80B PCGF1 TTC31 AUP1 MOGS CCDC142 DUSP11 ENSG00000273245 LBX2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around INO80B-WBP1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for INO80B-WBP1 Gene

Genomic Locations for INO80B-WBP1 Gene
chr2:74,455,023-74,460,891
(GRCh38/hg38)
Size:
5,869 bases
Orientation:
Plus strand
chr2:74,682,150-74,688,018
(GRCh37/hg19)

Genomic View for INO80B-WBP1 Gene

Genes around INO80B-WBP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INO80B-WBP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INO80B-WBP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INO80B-WBP1 Gene

Proteins for INO80B-WBP1 Gene

  • Protein details for INO80B-WBP1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8WCL7
    Recommended name:
    INO80B-WBP1 readthrough (NMD candidate)
    Protein Accession:
    F8WCL7

    Protein attributes for INO80B-WBP1 Gene

    Size:
    263 amino acids
    Molecular mass:
    29262 Da
    Quaternary structure:
    No Data Available
  • Protein details for INO80B-WBP1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    J3KQ70
    Recommended name:
    HCG2039827, isoform CRA_e
    Protein Accession:
    J3KQ70

    Protein attributes for INO80B-WBP1 Gene

    Size:
    363 amino acids
    Molecular mass:
    39432 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INO80B-WBP1 Gene

Post-translational modifications for INO80B-WBP1 Gene

No Post-translational modifications

Other Protein References for INO80B-WBP1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for INO80B-WBP1 Gene

Domains & Families for INO80B-WBP1 Gene

Protein Domains for INO80B-WBP1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with INO80B-WBP1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for INO80B-WBP1 Gene

Function for INO80B-WBP1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INO80B-WBP1 Gene

Localization for INO80B-WBP1 Gene

Gene Ontology (GO) - Cellular Components for INO80B-WBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031011 Ino80 complex IEA --
genes like me logo Genes that share ontologies with INO80B-WBP1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for INO80B-WBP1 Gene

Pathways & Interactions for INO80B-WBP1 Gene

SuperPathways for INO80B-WBP1 Gene

No Data Available

Interacting Proteins for INO80B-WBP1 Gene

Gene Ontology (GO) - Biological Process for INO80B-WBP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for INO80B-WBP1 Gene

Drugs & Compounds for INO80B-WBP1 Gene

No Compound Related Data Available

Transcripts for INO80B-WBP1 Gene

mRNA/cDNA for INO80B-WBP1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for INO80B-WBP1 Gene

No ASD Table

Relevant External Links for INO80B-WBP1 Gene

GeneLoc Exon Structure for
INO80B-WBP1
ECgene alternative splicing isoforms for
INO80B-WBP1

Expression for INO80B-WBP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for INO80B-WBP1 Gene

Protein differential expression in normal tissues from HIPED for INO80B-WBP1 Gene

This gene is overexpressed in Liver (40.8), CD8 Tcells (9.9), and Lung (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for INO80B-WBP1 Gene



Protein tissue co-expression partners for INO80B-WBP1 Gene

genes like me logo Genes that share expression patterns with INO80B-WBP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INO80B-WBP1 Gene

Orthologs for INO80B-WBP1 Gene

Evolution for INO80B-WBP1 Gene

ENSEMBL:
Gene Tree for INO80B-WBP1 (if available)
TreeFam:
Gene Tree for INO80B-WBP1 (if available)

No data available for Orthologs for INO80B-WBP1 Gene

Paralogs for INO80B-WBP1 Gene

Paralogs for INO80B-WBP1 Gene

genes like me logo Genes that share paralogs with INO80B-WBP1: view

Variants for INO80B-WBP1 Gene

Sequence variations from dbSNP and Humsavar for INO80B-WBP1 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs368859958 uncertain-significance, not specified, Congenital disorder of glycosylation 74,461,355(+) G/A/C downstream_transcript_variant
rs929416520 uncertain-significance, Congenital disorder of glycosylation 74,461,110(+) C/T downstream_transcript_variant
rs1000432692 -- 74,455,148(+) C/T non_coding_transcript_variant
rs1000448439 -- 74,461,214(+) G/C downstream_transcript_variant
rs1001347317 -- 74,457,113(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for INO80B-WBP1 Gene

Variant ID Type Subtype PubMed ID
esv2759061 CNV loss 17122850
nsv458185 CNV loss 19166990
nsv515851 CNV loss 19592680
nsv582214 CNV loss 21841781

Additional Variant Information for INO80B-WBP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INO80B-WBP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for INO80B-WBP1 Gene

Disorders for INO80B-WBP1 Gene

Additional Disease Information for INO80B-WBP1

No disorders were found for INO80B-WBP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for INO80B-WBP1 Gene

Publications for INO80B-WBP1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 58

Products for INO80B-WBP1 Gene

Sources for INO80B-WBP1 Gene

Content
Loading form....