Aliases for INO80B Gene
External Ids for INO80B Gene
Previous HGNC Symbols for INO80B Gene
Previous GeneCards Identifiers for INO80B Gene
This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011]
GeneCards Summary for INO80B Gene
INO80B (INO80 Complex Subunit B) is a Protein Coding gene. Among its related pathways are Transcription-Coupled Nucleotide Excision Repair (TC-NER) and DNA Double-Strand Break Repair. An important paralog of this gene is INO80B-WBP1.
UniProtKB/Swiss-Prot for INO80B Gene
Induces growth and cell cycle arrests at the G1 phase of the cell cycle.
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.