Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



INO80B Gene

protein-coding   GIFtS: 45
GCID: GC02P074682

INO80 Complex Subunit B

(Previous names: high mobility group AT-hook 1-like 4, zinc finger, HIT type...)
(Previous symbols: HMGA1L4, ZNHIT4)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
INO80 Complex Subunit B1 2     IES2 Homolog2 3
High Mobility Group AT-Hook 1-Like 41 2 3     PAP-1-Associated Protein 12 3
HMGA1L41 2 3     IES2 Homolog (S. Cerevisiae)1
ZNHIT41 2 3     HMGIYL42
Zinc Finger, HIT Type 41 2     IES22
PAP-1 Binding Protein1 2     PAP-1BP2
Zinc Finger HIT Domain-Containing Protein 42 3     PAP (Pim-1 Associated Protein) Associated Protein 12
PAPA-12 3     PAPA13
hIes22 3     

External Ids:    HGNC: 133241   Entrez Gene: 834442   Ensembl: ENSG000001152747   UniProtKB: Q9C0863   

Export aliases for INO80B gene to outside databases

Previous GC identifers: GC02P074536 GC02P074419


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for INO80B Gene:
This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and
nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene
into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding
transcript. (provided by RefSeq, Feb 2011)

GeneCards Summary for INO80B Gene:
INO80B (INO80 complex subunit B) is a protein-coding gene. Diseases associated with INO80B include malaria.

UniProtKB/Swiss-Prot: IN80B_HUMAN, Q9C086
Function: Induces growth and cell cycle arrests at the G1 phase of the cell cycle
Function: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional
regulation, DNA replication and probably DNA repair




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the INO80B gene promoter:
         HOXA9   ER-alpha   GR   p53   GCNF   E47   GCNF-1   Hand1   GR-alpha   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidINO80B promoter sequence
   Search Chromatin IP Primers for INO80B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat INO80B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p13.1   Ensembl cytogenetic band:  2p13.1   HGNC cytogenetic band: 2p13.1

INO80B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
INO80B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P074682:  view genomic region     (about GC identifiers)

Start:
74,682,150 bp from pter      End:
74,688,011 bp from pter
Size:
5,862 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: IN80B_HUMAN, Q9C086 (See protein sequence)
Recommended Name: INO80 complex subunit B  
Size: 356 amino acids; 38637 Da
Subunit: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated
with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with RP9
Sequence caution: Sequence=BAB21111.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Explore the universe of human proteins at neXtProt for INO80B: NX_Q9C086

Explore proteomics data for INO80B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See INO80B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112578.2  
    ENSEMBL proteins: 
     ENSP00000233331   ENSP00000389887   ENSP00000388677   ENSP00000392498   ENSP00000387267  
     ENSP00000386937   ENSP00000398740  

    INO80B Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for INO80B
    OriGene Custom MassSpec
    OriGene Custom Protein Services for INO80B
    GenScript Custom Purified and Recombinant Proteins Services for INO80B
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for INO80B

    INO80B Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for INO80B
    Novus Biologicals INO80B Antibodies
    Abcam antibodies for INO80B
    Cloud-Clone Corp. Antibodies for INO80B
    ThermoFisher Antibodies for INO80B
    LSBio Antibodies in human, mouse, rat for INO80B

    INO80B Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for INO80B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for INO80B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for INO80B
    Cloud-Clone Corp. CLIAs for INO80B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    INO80: INO80 complex subunits
    ZNHIT: Zinc fingers, HIT-type

    2 InterPro protein domains:
     IPR007529 Znf_HIT
     IPR006880 INO80B_C

    Graphical View of Domain Structure for InterPro Entry Q9C086

    ProtoNet protein and cluster: Q9C086

    UniProtKB/Swiss-Prot: IN80B_HUMAN, Q9C086
    Similarity: Contains 1 HIT-type zinc finger


    INO80B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IN80B_HUMAN, Q9C086
    Function: Induces growth and cell cycle arrests at the G1 phase of the cell cycle
    Function: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional
    regulation, DNA replication and probably DNA repair

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19095771
    GO:0046872metal ion binding IEA--
         
    INO80B for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Ino80b (no phenotypes)

    INO80B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for INO80B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for INO80B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for INO80B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for INO80B

    miRNA
    Products:
        
    miRTarBase miRNAs that target INO80B:
    hsa-mir-335-5p (MIRT018307), hsa-mir-484 (MIRT042253), hsa-mir-181b-5p (MIRT047255)

    Block miRNA regulation of human, mouse, rat INO80B using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate INO80B:
    hsa-miR-633
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for INO80B
    Predesigned siRNA for gene silencing in human, mouse, rat INO80B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for INO80B

    Clone
    Products:
         
    OriGene clones in human, mouse for INO80B (see all 7)
    OriGene ORF clones in mouse, rat for INO80B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: INO80B (NM_031288)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for INO80B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INO80B

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for INO80B
    Browse ESI BIO Cell Lines and PureStem Progenitors for INO80B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INO80B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    IN80B_HUMAN, Q9C086: Nucleus. Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane4
    cytosol2
    mitochondrion2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--
    GO:0031011Ino80 complex IDA--

    INO80B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Array including INO80B: 
              Polycomb & Trithorax Complexes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for INO80B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    Selected Interacting proteins for INO80B (Q9C0861, 2, 3 ENSP000002333314) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UIMC1Q96RL12, 3, ENSP000003664344MINT-65401 I2D: score=4 STRING: ENSP00000366434
    IGFBP2P180651, 3, ENSP000002338094EBI-715611,EBI-2504392 I2D: score=1 STRING: ENSP00000233809
    CD81P600332, 3, ENSP000002636454MINT-65400 I2D: score=5 STRING: ENSP00000263645
    ACTR5Q9H9F93, ENSP000002439034I2D: score=2 STRING: ENSP00000243903
    ACTR8Q9H9813, ENSP000003368424I2D: score=2 STRING: ENSP00000336842
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair IEA--
    GO:0006310DNA recombination IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    INO80B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for INO80B (IN80B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for INO80B gene: 
    NM_031288.3  

    Unigene Cluster for INO80B:

    INO80 complex subunit B
    Hs.410786  [show with all ESTs]
    Unigene Representative Sequence: NR_037849
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000233331(uc002slg.3 uc010yrr.2 uc010yrs.2) ENST00000431187
    ENST00000452361(uc002sli.2) ENST00000494986 ENST00000441673 ENST00000409917
    ENST00000471577 ENST00000473618 ENST00000409493 ENST00000469849 ENST00000455562

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat INO80B using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate INO80B:
    hsa-miR-633
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for INO80B
    Predesigned siRNA for gene silencing in human, mouse, rat INO80B
    Clone
    Products:
         
    OriGene clones in human, mouse for INO80B (see all 7)
    OriGene ORF clones in mouse, rat for INO80B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: INO80B (NM_031288)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for INO80B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INO80B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for INO80B
    OriGene qSTAR qPCR primer pairs in human, mouse for INO80B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat INO80B
      QuantiTect SYBR Green Assays in human, mouse, rat INO80B
      QuantiFast Probe-based Assays in human, mouse, rat INO80B

    Additional mRNA sequence: 

    AB054538.1 AK295889.1 AK295901.1 BC039617.1 BC050666.2 BC064425.1 NR_037849.1 

    11 DOTS entries:

    DT.310026  DT.100823654  DT.120976802  DT.92427515  DT.100818530  DT.101981488  DT.97855589  DT.100818531 
    DT.92427519  DT.86855554  DT.86855555 

    Selected AceView cDNA sequences (see all 476):

    BC071626 BQ069051 AI399670 BM718348 CB306223 BM700467 CN480311 BC010012 
    BU728507 BF726607 BM470922 CR613137 CR607952 Z38557 AI871034 BQ420303 
    AW054812 CA433506 AI656663 BI256785 BM696101 BM921627 BM672983 BQ720263 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    INO80B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGCTCTTG
    INO80B Expression
    About this image

    INO80B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    INO80B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.410786
        Pathway & Disease-focused RT2 Profiler PCR Array including INO80B: 
              Polycomb & Trithorax Complexes in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for INO80B
    OriGene qSTAR qPCR primer pairs in human, mouse for INO80B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat INO80B
    QuantiTect SYBR Green Assays in human, mouse, rat INO80B
    QuantiFast Probe-based Assays in human, mouse, rat INO80B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INO80B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for INO80B gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ino80b1 , 5 INO80 complex subunit B1, 5 82.22(n)1
    90.67(a)1
      6 (35.94 cM)5
    700201  NM_023547.11  NP_076036.11 
     831217655 
    lizard
    (Anolis carolinensis)
    Reptilia INO80B6
    INO80 complex subunit B
    66(a)
    1 ↔ 1
    GL344203.1(40243-46894)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.59882 Xenopus laevis transcribed sequence with weak similarity more 77.67(n)    BQ736030.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ino80b1 INO80 complex subunit B 63.78(n)
    60.53(a)
      768122  NM_001077258.1  NP_001070726.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG103956
    --
    26(a)
    1 ↔ 1
    2R(1237998-1239477)


    ENSEMBL Gene Tree for INO80B (if available)
    TreeFam Gene Tree for INO80B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    1 SNPs for INO80B    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs10542091,2,4
    ----see VAR_0550832 mis40--------

    HapMap Linkage Disequilibrium report for INO80B (74682150 - 74688011 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for INO80B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv458185CNV Loss19166990
    nsv515851CNV Loss19592680
    dgv4166n71CNV Loss21882294
    dgv1199e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing INO80B
    DNA2.0 Custom Variant and Variant Library Synthesis for INO80B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for INO80B:    
    About MalaCards
    malaria


    INO80B for disorders           About GeneDecksing


    Export disorders for INO80B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for INO80B gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with INO80B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. (PubMed id 16230350)1, 2, 3 Jin J.... Conaway J.W. (J. Biol. Chem. 2005)
    2. A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase. (PubMed id 15556297)1, 2, 9 Kuroda T.S....Iguchi-Ariga S.M.M. (Gene 2004)
    3. Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. (PubMed id 21303910)1, 2 Chen L.... Conaway R.C. (J. Biol. Chem. 2011)
    4. Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. (PubMed id 18922472)1, 2 Yao T.... Conaway J.W. (Mol. Cell 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A whole genome screen for HIV restriction factors. (PubMed id 22082156)1 Liu L....McKnight A. (Retrovirology 2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    8. PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions. (PubMed id 19095771)1 Miyako K....Cohen P. (Mol. Endocrinol. 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 83444 HGNC: 13324 AceView: WBP1andHMGA1L4 Ensembl:ENSG00000115274 euGenes: HUgn83444
    ECgene: INO80B H-InvDB: INO80B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for INO80B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for INO80B gene:
    Search GeneIP for patents involving INO80B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for INO80B  
     OriGene qPCR primer pairs and template standards for INO80B   OriGene Protein Over-expression Lysate for INO80B  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for INO80B  
     OriGene qSTAR qPCR primer pairs in human, mouse for INO80B   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for INO80B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for INO80B   OriGene Custom Protein Services for INO80B  

     
     
     Block miRNA regulation of human, mouse, rat INO80B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing INO80B
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat INO80B Predesigned siRNA for gene silencing in human, mouse, rat INO80B
     QuantiFast Probe-based Assays in human, mouse, rat INO80B QuantiTect SYBR Green Assays in human, mouse, rat INO80B
     PCR Arrays including human, mouse, rat INO80B Search Chromatin IP Primers for INO80B
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat INO80B  Search GeneGlobe Interaction Network for INO80B
     Regulatory tfbs in INO80B promoter
     GenScript Custom Purified and Recombinant Proteins Services for INO80B GenScript cDNA clones with any tag delivered in your preferred vector for INO80B
     GenScript Custom Assay Services for INO80B GenScript Custom overexpressing Cell Line Services for INO80B
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for INO80B (IN80B)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     INO80B antibodies
     Antibodies for INO80B
     See all of Abcam's Antibodies, Kits and Proteins for INO80B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for INO80B
     Antibodies for INO80B
     ELISAs for INO80B
     CLIAs for INO80B



     Browse ESI BIO Cell Lines and PureStem Progenitors for INO80B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INO80B
     Browse SwitchGear 3'UTR luciferase reporter plasmids for INO80B
     SwitchGear Promoter luciferase reporter plasmids for INO80B
     ThermoFisher Antibodies for INO80B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INO80B
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for INO80B
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for INO80B
     LSBio Antibodies in human, mouse, rat for INO80B
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      INO80B gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4