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Aliases for INMT-FAM188B Gene

Subcategory (RNA class) for INMT-FAM188B Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for INMT-FAM188B Gene

  • INMT-FAM188B Readthrough (NMD Candidate) 2 3

External Ids for INMT-FAM188B Gene

Previous GeneCards Identifiers for INMT-FAM188B Gene

  • GC07U903112

Summaries for INMT-FAM188B Gene

Entrez Gene Summary for INMT-FAM188B Gene

  • This locus represents rare but naturally occurring read-through transcription between the INMT (indolethylamine N-methyltransferase) and FAM188B (family with sequence similarity 188, member B) genes on chromosome 7. The read-through transcript is unlikely to produce a protein because it is a nonsense-mediated mRNA decay (NMD) candidate based on translation from the supported INMT start codon. [provided by RefSeq, Nov 2010]

GeneCards Summary for INMT-FAM188B Gene

INMT-FAM188B (INMT-FAM188B Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is NNMT.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INMT-FAM188B Gene

Genomics for INMT-FAM188B Gene

Genomic Location for INMT-FAM188B Gene

Start:
30,752,135 bp from pter
End:
30,892,387 bp from pter
Size:
140,253 bases
Orientation:
Plus strand

Genomic View for INMT-FAM188B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for INMT-FAM188B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INMT-FAM188B Gene

No data available for Regulatory Elements for INMT-FAM188B Gene

Proteins for INMT-FAM188B Gene

  • Protein details for INMT-FAM188B Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8WBC2
    Recommended name:
    Protein INMT-FAM188B
    Protein Accession:
    F8WBC2
    Secondary Accessions:

    Protein attributes for INMT-FAM188B Gene

    Size:
    141 amino acids
    Molecular mass:
    15818 Da
    Quaternary structure:
    No Data Available
  • Protein details for INMT-FAM188B Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BSR8
    Recommended name:
    Protein INMT-FAM188B
    Protein Accession:
    H3BSR8
    Secondary Accessions:

    Protein attributes for INMT-FAM188B Gene

    Size:
    122 amino acids
    Molecular mass:
    13650 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INMT-FAM188B Gene

Proteomics data for INMT-FAM188B Gene at MOPED

Post-translational modifications for INMT-FAM188B Gene

No Post-translational modifications

Other Protein References for INMT-FAM188B Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for INMT-FAM188B Gene

Domains for INMT-FAM188B Gene

Protein Domains for INMT-FAM188B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with INMT-FAM188B: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for INMT-FAM188B Gene

Function for INMT-FAM188B Gene

Gene Ontology (GO) - Molecular Function for INMT-FAM188B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity --
genes like me logo Genes that share ontologies with INMT-FAM188B: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for INMT-FAM188B Gene

Localization for INMT-FAM188B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for INMT-FAM188B Gene

Pathways for INMT-FAM188B Gene

SuperPathways for INMT-FAM188B Gene

No Data Available

Interacting Proteins for INMT-FAM188B Gene

Gene Ontology (GO) - Biological Process for INMT-FAM188B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation --
genes like me logo Genes that share ontologies with INMT-FAM188B: view

No data available for Pathways by source for INMT-FAM188B Gene

Transcripts for INMT-FAM188B Gene

mRNA/cDNA for INMT-FAM188B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for INMT-FAM188B Gene

No ASD Table

Relevant External Links for INMT-FAM188B Gene

GeneLoc Exon Structure for
INMT-FAM188B
ECgene alternative splicing isoforms for
INMT-FAM188B

Expression for INMT-FAM188B Gene

mRNA expression in normal human tissues for INMT-FAM188B Gene

mRNA differential expression in normal tissues according to GTEx for INMT-FAM188B Gene

This gene is overexpressed in Artery - Coronary (7.3), Lung (5.4), and Artery - Tibial (4.5).
genes like me logo Genes that share expressions with INMT-FAM188B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for INMT-FAM188B Gene

Orthologs for INMT-FAM188B Gene

This gene was present in the common ancestor of animals.

Orthologs for INMT-FAM188B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 47 (a)
OneToMany
cow
(Bos Taurus)
Mammalia INMT 36
  • 27 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 26 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Inmt 36
  • 28 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 25 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 6 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 6 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii zgc:64002 36
  • 21 (a)
ManyToMany
zgc:64002 36
  • 20 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea anmt-1 36
  • 11 (a)
ManyToMany
anmt-2 36
  • 15 (a)
ManyToMany
anmt-3 36
  • 11 (a)
ManyToMany
Species with no ortholog for INMT-FAM188B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for INMT-FAM188B Gene

ENSEMBL:
Gene Tree for INMT-FAM188B (if available)
TreeFam:
Gene Tree for INMT-FAM188B (if available)

Paralogs for INMT-FAM188B Gene

Paralogs for INMT-FAM188B Gene

Selected SIMAP similar genes for INMT-FAM188B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with INMT-FAM188B: view

Variants for INMT-FAM188B Gene

Sequence variations from dbSNP and Humsavar for INMT-FAM188B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1860510 -- 30,760,082(+) CTGAG(G/T)GACTA intron-variant
rs1860511 -- 30,763,900(+) ATAGA(A/G)AAAAA intron-variant
rs1860512 -- 30,764,032(+) CTTCT(A/C)TCTTA intron-variant
rs1860513 -- 30,764,200(+) GTGCT(C/G)ATGCT intron-variant
rs2013200 -- 30,766,195(+) ATTTc(A/T)cacac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for INMT-FAM188B Gene

Variant ID Type Subtype PubMed ID
nsv436557 CNV Deletion 17901297
nsv527038 CNV Gain 19592680
nsv830938 CNV Gain 17160897
nsv830939 CNV Loss 17160897
nsv464416 CNV Loss 19166990
esv269741 CNV Insertion 20981092
nsv526591 CNV Loss 19592680
esv2734203 CNV Deletion 23290073
esv22626 CNV Gain 19812545
esv2678492 CNV Deletion 23128226
esv2390406 CNV Deletion 18987734
esv5109 CNV Deletion 18987735
esv2678752 CNV Deletion 23128226
esv2734204 CNV Deletion 23290073
esv5499 CNV Loss 19470904
esv993279 CNV Deletion 20482838

Relevant External Links for INMT-FAM188B Gene

HapMap Linkage Disequilibrium report
INMT-FAM188B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for INMT-FAM188B Gene

Disorders for INMT-FAM188B Gene

No disorders were found for INMT-FAM188B Gene.

No data available for UniProtKB/Swiss-Prot for INMT-FAM188B Gene

Publications for INMT-FAM188B Gene

  1. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for INMT-FAM188B Gene

Sources for INMT-FAM188B Gene

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