INMT-FAM188B Gene
protein-coding GIFtS: 21
GCID: GC07P030792
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INMT-FAM188B readthrough (non-protein coding)
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Aliases
for INMT-FAM188B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| INMT-FAM188B Readthrough (Non-Protein Coding)1 2 |
| External Ids: | HGNC: 419951 | Entrez Gene: 1005268252 | Ensembl: ENSG000002549597 | UniProtKB: F8WBC24 | UniProtKB: H3BSR84 |
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| | ORGUL members: | |
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| NONCODE:n410455 | |
Export aliases for INMT-FAM188B gene to outside databasesPrevious GC identifer: GC07U903112
Summaries
for INMT-FAM188B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for INMT-FAM188B:
This locus represents rare but naturally occurring read-through transcription between the INMT (indolethylamineN-methyltransferase) and FAM188B (family with sequence similarity 188, member B) genes on chromosome 7. Theread-through transcript is unlikely to produce a protein because it is a nonsense-mediated mRNA decay (NMD) candidatebased on translation from the supported INMT start codon. (provided by RefSeq, Nov 2010)
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Genomic Views
for INMT-FAM188B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for INMT-FAM188B
Other transcription factors
Search SABiosciences Chromatin IP Primers for INMT-FAM188B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INMT-FAM188B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p Ensembl cytogenetic band: 7p14.3 HGNC cytogenetic band: 7p14.3INMT-FAM188B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P030792: view genomic region
(about GC identifiers)
Start:
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30,791,753 bp from pter |
End:
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30,931,696 bp from pter |
Size:
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139,944 bases |
Orientation:
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plus strand |
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Proteins
for INMT-FAM188B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/TrEMBL: F8WBC2 (See
protein sequence)Recommended Name: Protein INMT-FAM188B Size: 141 amino acids; 15818 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: H3BSR8 (See
protein sequence) Recommended Name: Protein INMT-FAM188B Size: 122 amino acids; 13650 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataINMT-FAM188B Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000456039 ENSP00000456833
Human Recombinant Protein Products:
INMT-FAM188B Antibody Products:
Assay Products for INMT-FAM188B: |
Protein
Domains /
Families
for INMT-FAM188B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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INMT-FAM188B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry F8WBC2Graphical View of Domain Structure for InterPro Entry H3BSR8ProtoNet protein and cluster: F8WBC2 |
Function
for INMT-FAM188B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INMT-FAM188B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0008168 | methyltransferase activity |
-- | -- |
INMT-FAM188B for ontologies About GeneDecksing
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Pathways & Interactions
for INMT-FAM188B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for INMT-FAM188B
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Drugs & Compounds
for INMT-FAM188B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for INMT-FAM188B
Search CenterWatch for drugs/clinical trials and news about INMT-FAM188B 
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Transcripts
for INMT-FAM188B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000458257(uc010kwe.3) ENST00000451002
GeneLoc Exon Structure
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Expression
for INMT-FAM188B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| INMT-FAM188B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for INMT-FAM188B
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat INMT-FAM188B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INMT-FAM188B | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INMT-FAM188B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INMT-FAM188B |
Orthologs
for INMT-FAM188B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for INMT-FAM188B gene from 3/7 species (see all 7) About this table
ENSEMBL Gene Tree for INMT-FAM188B (if available)
TreeFam Gene Tree for INMT-FAM188B (if available) |
Paralogs
for INMT-FAM188B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for INMT-FAM188B gene
- PNMT2 NNMT2 INMT2
3 SIMAP similar genes for INMT-FAM188B using alignment to 2 protein entries: F8WBC2_HUMAN (see all proteins):INMT NNMT PNMT
INMT-FAM188B for paralogs About GeneDecksing
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Genomic Variants
for INMT-FAM188B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for INMT-FAM188B (30791753 - 30931696 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for INMT-FAM188B: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for INMT-FAM188B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for INMT-FAM188B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for INMT-FAM188B gene integrated from 9 sources:
(articles sorted by number of sources associating them with INMT-FAM188B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1 Hillier L.W.... Wilson R.K. (2003)
- Toward a complete human genome sequence. (PubMed id 9847074)1 Wilson R. (1998)
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External Searches for INMT-FAM188B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing INMT-FAM188B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing INMT-FAM188B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing INMT-FAM188B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for INMT-FAM188B gene:
Search GeneIP for patents involving INMT-FAM188B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for INMT-FAM188B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat INMT-FAM188B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INMT-FAM188B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INMT-FAM188B | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat INMT-FAM188B | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INMT-FAM188B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INMT-FAM188B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INMT-FAM188B |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat INMT-FAM188B |
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