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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

INHBE Gene

protein-coding GIFtS: 52
GCID: GC12P057849

inhibin, beta E

Explore 15 diseases affiliated with
INHBE via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Inhibin, Beta E¹ ²
Activin Beta-E Chain² ³
MGC4638¹
Activin¹
Activin Beta E²
Inhibin Beta E Chain²

External Ids:	HGNC: 24029¹	Entrez Gene: 83729²	Ensembl: ENSG00000139269⁷	OMIM: 612031⁵	UniProtKB: P58166³

Export aliases for INHBE gene to outside databases

Previous GC identifers: GC12P057992 GC12P057565 GC12P056135 GC12P054886

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for INHBE:

INHBE is a member of the activin beta family (see INHBA; MIM 147290) that plays a role in pancreatic exocrine cell

growth and proliferation (Hashimoto et al., 2006 (PubMed 16426570)).(supplied by OMIM, May 2008)

UniProtKB/Swiss-Prot: INHBE_HUMAN, P58166

Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary

gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary

hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin

secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.

Inhibins appear to oppose the functions of activins

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the INHBE gene promoter:
NF-1 Sp1 p53 c-Myb Nkx2-5 STAT5A
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: INHBE promoter sequence

Search SABiosciences Chromatin IP Primers for INHBE

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INHBE

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13.2

INHBE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
INHBE gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P057849: view genomic region (about GC identifiers)

Start:	57,846,106 bp from pter	End:	57,853,063 bp from pter
Size:	6,958 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: INHBE_HUMAN, P58166 (See protein sequence)

Recommended Name: Inhibin beta E chain precursor

Size: 350 amino acids; 38561 Da

Subunit: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide

bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta

subunits only (By similarity)

Subcellular location: Secreted (By similarity)

Explore the universe of human proteins at neXtProt for INHBE: NX_P58166

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P58166

INHBE Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_113667.1

ENSEMBL proteins:

ENSP00000450212 ENSP00000266646

Human Recombinant Protein Products for INHBE:

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	Novus Biologicals INHBE Protein Novus Biologicals INHBE Lysates
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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--

INHBE for ontologies About GeneDecksing

INHBE Antibody Products:

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Assay Products for INHBE:

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

INHBE for domains About GeneDecksing

5 InterPro domains/families:

IPR001318 Inhibin_betaC

IPR001111 TGF-b_N

IPR015615 TGF-beta-rel

IPR001839 TGF-b_C

IPR017948 TGFb_CS

Graphical View of Domain Structure for InterPro Entry P58166

ProtoNet protein and cluster: P58166

2 Blocks protein families:

IPB001839 Transforming growth factor beta (TGFb)

IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: INHBE_HUMAN, P58166

Similarity: Belongs to the TGF-beta family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: INHBE_HUMAN, P58166

Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary

gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary

hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin

secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.

Inhibins appear to oppose the functions of activins

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005179	hormone activity	IEA	--
GO:0008083	growth factor activity	IEA	--

INHBE for ontologies About GeneDecksing

Phenotypes:
1 MGI mutant phenotype (inferred from 3 alleles) (MGI details for Inhbe):

normal

INHBE for phenotypes About GeneDecksing

Animal Models:
Mouse knock-outs for INHBE: Inhbe/Inhbc^Inhbe/tm1Sjl Inhbe^tm1Zuk Inhbe^tm2Zuk

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for INHBE

miRNA Products:		OriGene 3'-UTR Clone: INHBE Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat INHBE
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate INHBE (see all 12):
		hsa-miR-30c-2* hsa-miR-875-3p hsa-miR-3194-5p hsa-miR-548aa hsa-miR-1224-5p hsa-miR-3171 hsa-miR-548l hsa-miR-30c-1*

		SwitchGear 3'UTR luciferase reporter plasmid: INHBE 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for INHBE (see all 7) OriGene shRNA RFP: INHBE OriGene siRNA: INHBE
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		Sirion Biotech Custom design and validation of potent shRNA sequences against INHBE

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for INHBE
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INHBE (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INHBE OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: INHBE (NM_031479)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INHBE

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

TGF-beta signaling pathway

TGF-beta signaling pathway

1.00

PEDF Induced Signaling

Cytokine-cytokine receptor interaction

0.26

Pathway sources
See GeneCards unified pathways
Show all pathways

2 Kegg Pathways (Kegg details for INHBE):

	Cytokine-cytokine receptor interaction
	TGF-beta signaling pathway

INHBE for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for INHBE

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

5/17 Interacting proteins for INHBE (P58166³ ENSP00000266646⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FST	P19883³, ENSP00000256759⁴	I2D: score=2 STRING: ENSP00000256759
PTEN	P60484³, ENSP00000361021⁴	I2D: score=1 STRING: ENSP00000361021
CGA	ENSP00000358595⁴	STRING: ENSP00000358595
FSHB	ENSP00000254122⁴	STRING: ENSP00000254122
INHA	ENSP00000243786⁴	STRING: ENSP00000243786

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0040007	growth	IEA	--

INHBE for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for INHBE
Search CenterWatch for drugs/clinical trials and news about INHBE

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for INHBE gene:

NM_031479.3

Unigene Cluster for INHBE:

Inhibin, beta E

Hs.632713 [show with all ESTs]

Unigene Representative Sequence: AF412024

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000551553 ENST00000547970 ENST00000266646(uc001snw.3) ENST00000553033

miRNA Products:		OriGene 3'-UTR Clone: INHBE Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat INHBE
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate INHBE (see all 12):
		hsa-miR-30c-2* hsa-miR-875-3p hsa-miR-3194-5p hsa-miR-548aa hsa-miR-1224-5p hsa-miR-3171 hsa-miR-548l hsa-miR-30c-1*

		SwitchGear 3'UTR luciferase reporter plasmid: INHBE 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for INHBE (see all 7) OriGene shRNA RFP: INHBE OriGene siRNA: INHBE
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat INHBE
		Sirion Biotech Custom design and validation of potent shRNA sequences against INHBE

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INHBE (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INHBE OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: INHBE (NM_031479)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for INHBE
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INHBE

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INHBE Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat INHBE
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INHBE
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INHBE

Additional cDNA sequence:

AF412024.1 AK075285.1 AK308647.1 BC005161.2

2 DOTS entries:

DT.100019870 DT.40199098

24/40 AceView cDNA sequences (see all 40):

AA113781 BM471716 NM_031479 BC005161 BQ772988 BE294509 AK075285 BU632022

BX331898 BF205858 AL519989 BE296212 BE297378 BG826333 BE294783 AL519988

AF412024 BF305560 BG826538 BF309695 BE298480 BF204851 AA112414 BE250645

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

INHBE expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATTACATC

About this image

INHBE expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

N2/LSB/S/F8/CHIR-induced cells (Generation of midbra...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See INHBE Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for INHBE

SOURCE GeneReport for Unigene cluster: Hs.632713

SABiosciences Expression via Pathway-Focused PCR Arrays including INHBE:

Fibrosis in human mouse rat

Molecular Toxicology PathwayFinder 384HT in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INHBE Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INHBE

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INHBE

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for INHBE gene from 3/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	--	--	40(a)	1 → many	GL343212.1(901902-904866)
zebrafish (Danio rerio)	Actinopterygii	CABZ01117503.1⁶	--	34(a)	1 → many	1(30609327-30615423)
fruit fly (Drosophila melanogaster)	Insecta	Actbeta⁶	Activin-beta	8(a)	1 → many	4(1097946-1105418)

ENSEMBL Gene Tree for INHBE (if available)
TreeFam Gene Tree for INHBE (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for INHBE gene

TGFB3² INHBC² GDF11² MSTN² INHBA² TGFB1² INHBB² TGFB2²

3 SIMAP similar genes for INHBE using alignment to 2 protein entries: INHBE_HUMAN (see all proteins):

DKFZp686A06204 INHBC INHBB

INHBE for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186915687^1,2		--	57847117(+)	`GTGGAA/GGGGTC`	1	--	us2k¹		0	--	--	--	--
rs34384030^1,2	C	--	57847127(+)	`TGGGT-/CCCCCC`	1	--	us2k¹		0	--	--	--	--
rs189187055^1,2		--	57847182(+)	`TAATCC/TTAGCG`	1	--	us2k¹		0	--	--	--	--
rs116293069^1,2	F	--	57847226(+)	`CCCAGG/AAGCTT`	1	--	us2k¹		1		WA	118
rs145710430^1,2		--	57847295(+)	`TAGCCG/TGTGTG`	1	--	us2k¹		0	--	--	--	--
rs147296895^1,2		--	57847389(+)	`CAGGAG/TGTCAA`	1	--	us2k¹		0	--	--	--	--
rs181948081^1,2		--	57847819(+)	`TGGTCA/CGGAGG`	1	--	us2k¹		0	--	--	--	--
rs139842205^1,2		--	57847924(+)	`GGGTGA/GTGCGG`	1	--	us2k¹		0	--	--	--	--
rs76149603^1,2	C,F	--	57847937(+)	`GCTCAA/C/TGCCTG`	1	--	us2k¹		3		WA NA EA	358
rs703845^1,2	C,F,A,H	--	57847938(+)	`CTCACG/ACCTGT`	1	--	us2k¹		6		NA CSA WA EA	363

HapMap Linkage Disequilibrium report for INHBE (57846106 - 57853063 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for INHBE
1 CNV: 3891

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INHBE

DNA2.0 Custom Variant and Variant Library Synthesis for INHBE

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

INHBE for disorders           About GeneDecksing

OMIM gene information: 612031    OMIM disorders: --

15 diseases for INHBE:    About MalaCards

fibrodysplasia ossificans progressiva pre-eclampsia pancreatitis hereditary hemorrhagic telangiectasia

testicular germ cell tumor germ cell tumor wolfram syndrome eclampsia

endometrial adenocarcinoma cervical cancer cervicitis nasopharyngitis

adenocarcinoma neuronitis carcinoma

1 disease from the University of Copenhagen DISEASES database for INHBE:

Wolfram syndrome

Human Genome Epidemiology (HuGE) Navigator: INHBE (2 documents)

Export disorders for INHBE gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for INHBE gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with INHBE)

Utopia: connect your pdf to the dynamic
world of online information

cDNA cloning and expression of human activin betaE subunit. (PubMed id 12242034)^{1, 2, 3, 9} Hashimoto O....Hasegawa Y. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Inhibin/activin-betaE subunit in normal and malignant human cervical tissue and cervical cancer cell lines. (PubMed id 20033758)^{1, 9} Bergauer F....Mylonas I. (2009)
Genetic variation in the inhibin pathway and risk of testicular germ cell tumors. (PubMed id 18413775)^{1, 9} Purdue M.P....McGlynn K.A. (2008)
Inhibin/activin-betaC and -betaE subunits in the Ishi kawa human endometrial adenocarcinoma cell line. (PubMed id 20012305)¹ Kimmich T....Mylonas I. (2010)
A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)¹ He C....Hunter D.J. (2010)
Evidence of inhibin/activin subunit betaC and betaE s ynthesis in normal human endometrial tissue. (PubMed id 21092084)¹ Mylonas I....Kupka M.S. (2010)
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)² Chen R.... Zou H. (2009)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 83729	HGNC: 24029	AceView: INHBE	Ensembl:ENSG00000139269	euGenes: HUgn83729
ECgene: INHBE	Kegg: 83729	H-InvDB: INHBE

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for INHBE	Pharmacogenomics, SNPs, Pathways

Intellectual Property for INHBE gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for INHBE gene:
Search GeneIP for patents involving INHBE

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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