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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ING5 Gene

protein-coding   GIFtS: 53
GCID: GC02P242641

inhibitor of growth family, member 5
 Explore 6 diseases affiliated with
ING5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ING5    

Aliases
for ING5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Inhibitor Of Growth Family, Member 51 2
P28ING51
FLJ238421
Inhibitor Of Growth Protein 52

External Ids:    HGNC: 194211   Entrez Gene: 842892   Ensembl: ENSG000001683957   OMIM: 6085255   UniProtKB: Q8WYH83   

Export aliases for ING5 gene to outside databases

Previous GC identifers: GC02M238853 GC02M239540 GC02P242661 GC02P242962 GC02P242361 GC02P242291 GC02P234396


Summaries
for ING5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ING5:
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit
cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in
chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase
complex, suggesting its involvement in TP53-dependent regulatory pathway. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ING5_HUMAN, Q8WYH8
Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex
which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and
may function as a transcriptional coactivator

Gene Wiki entry for ING5


Genomic Views
for ING5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005416.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ING5 gene promoter:
         NF-1   NF-1/L   GATA-3   Lmo2   Nkx2-5   Nkx5-1   AREB6   PPAR-gamma1   PPAR-gamma2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ING5 promoter sequence
   Search SABiosciences Chromatin IP Primers for ING5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ING5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

ING5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ING5 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P242641:  view genomic region     (about GC identifiers)

Start:
 242,641,450 bp from pter      End:
 242,668,896 bp from pter
Size:
 27,447 bases      Orientation:
 plus strand

Proteins
for ING5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ING5_HUMAN, Q8WYH8 (See protein sequence)
Recommended Name: Inhibitor of growth protein 5  
Size: 240 amino acids; 27751 Da
Subunit: Interacts with H3K4me3 and to a lesser extent with H3K4me2. Component of the HBO1 complex composed at least of
ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17. Component of the MOZ/MORF complex composed at least
of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts with EP300 and TP53
Subcellular location: Nucleus
1 PDB 3D structure from and Proteopedia for ING5:
3C6W (3D)    
Secondary accessions: A8K1P3 Q53NU6 Q57Z54 Q9BS30
Alternative splicing: 2 isoforms:  Q8WYH8-1   Q8WYH8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ING5: NX_Q8WYH8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WYH8

    • ING5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_115705.2  
    ENSEMBL proteins: 
     ENSP00000322142   ENSP00000385937   ENSP00000416878  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: ING5
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    Novus Biologicals ING5 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ING5

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA18794358
    GO:0070776MOZ/MORF histone acetyltransferase complex IDA18794358


    ING5 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ING5

    Protein Domains /
    Families
    for ING5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ING5 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR024610 ING_N
     IPR019786 Zinc_finger_PHD-type_CS
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q8WYH8

    ProtoNet protein and cluster: Q8WYH8

    1 Blocks protein family: IPB001965 Zn-finger-like

    UniProtKB/Swiss-Prot: ING5_HUMAN, Q8WYH8
    Domain: The PHD-type zinc finger mediates the binding to H3K4me3
    Similarity: Belongs to the ING family
    Similarity: Contains 1 PHD-type zinc finger


    Function
    for ING5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ING5_HUMAN, Q8WYH8
    Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
    toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex
    which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and
    may function as a transcriptional coactivator

    miRNA
    Products:            		 OriGene 3'-UTR Clone: ING5
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ING5
    8/56 QIAGEN miScript miRNA Assays for microRNAs that regulate ING5 (see all 56):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-548j hsa-miR-640 hsa-miR-193a-3p hsa-miR-379* hsa-miR-513a-5p hsa-miR-128
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ING5 (see all 7)
    OriGene shRNA RFP: ING5
    OriGene siRNA: ING5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ING5

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ING5

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ING5 

    Cell Line
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    Search LifeMap BioReagents cell lines for ING5

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ING5

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12750254
    GO:0008270zinc ion binding IEA--
    GO:0035064methylated histone residue binding IDA16728974


    ING5 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ING5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ING5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/39 Interacting proteins for ING5 (Q8WYH82, 3 ENSP000003221424) via UniProtKB, MINT, STRING, and/or I2D (see all 39)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TADA3O755282, 3, ENSP000003076844MINT-3979398 I2D: score=4 STRING: ENSP00000307684
    KIAA1377Q9P2H02, 3, ENSP000002634684MINT-3981169 I2D: score=3 STRING: ENSP00000263468
    VIMP086702, 3, ENSP000002242374MINT-3980438 I2D: score=3 STRING: ENSP00000224237
    APLP1P516932, 3, ENSP000002218914MINT-3979876 I2D: score=2 STRING: ENSP00000221891
    PARP2Q9UGN52, 3, ENSP000002504164MINT-8201859 I2D: score=1 STRING: ENSP00000250416
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication IDA16387653
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006473protein acetylation IDA12750254
    GO:0008285negative regulation of cell proliferation IGI--
    GO:0043065positive regulation of apoptotic process IGI--


    ING5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ING5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ING5
    Search CenterWatch for drugs/clinical trials and news about ING5 

    Transcripts
    for ING5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ING5 gene: 
    NM_032329.4  

    Unigene Cluster for ING5:

    Inhibitor of growth family, member 5
    Hs.529172  [show with all ESTs]
    Unigene Representative Sequence: NM_032329
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000492488 ENST00000313552(uc002wcd.3) ENST00000482774 ENST00000406941
    ENST00000493261 ENST00000445620 ENST00000489509(uc021vzk.1) ENST00000484145
    ENST00000493578 ENST00000474238 ENST00000486061

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ING5
    8/56 QIAGEN miScript miRNA Assays for microRNAs that regulate ING5 (see all 56):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-548j hsa-miR-640 hsa-miR-193a-3p hsa-miR-379* hsa-miR-513a-5p hsa-miR-128
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ING5 (see all 7)
    OriGene shRNA RFP: ING5
    OriGene siRNA: ING5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ING5
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ING5 (NM_032329)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ING5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ING5 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ING5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ING5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ING5

    Additional cDNA sequence: 

    AF189286.1 AK074422.1 AK128322.1 AK289958.1 AK300790.1 AY203944.1 BC005370.1 BC039028.1 
    BC071899.1 

    10 DOTS entries:

    DT.109463  DT.95157863  DT.95097414  DT.95147505  DT.40267004  DT.40276527  DT.97772176  DT.100667978 
    DT.100744199  DT.95293497 

    24/130 AceView cDNA sequences (see all 130):

    CK906087 BQ683118 BU149727 BU629905 BE218301 AW195045 AA353456 CB055130 
    CK906086 AI675196 BC071899 AI972491 AI868796 AF189286 CA842795 BQ679158 
    AW614473 AI337313 H69731 BQ677883 AI124772 AW818264 BU509620 BQ678481 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ING5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                            -     -     -     -                 -         
    SP2:                                            -     -     -     -                           
    SP3:                                            -                                             
    SP4:                                            -           -                                 
    SP5:                                                                                          


    ECgene alternative splicing isoforms for ING5

    Expression
    for ING5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ING5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTATAGATTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See ING5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ING5

    SOURCE GeneReport for Unigene cluster: Hs.529172
        SABiosciences Expression via Pathway-Focused PCR Array including ING5: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

    Primer
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    In Situ
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    Orthologs
    for ING5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ING5 gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ING51 inhibitor of growth family, member 5 84.07(n)
    90.71(a)    		   424852  NM_001031312.1  NP_001026483.1 
    lizard
    (Anolis carolinensis)    		 Reptilia ING56
    		 --
    		 86(a)
    		 1 ↔ 1
    		 3(30571928-30582605)
    African clawed frog
    (Xenopus laevis)    		 Amphibia CA794009.12   -- 78.04(n)    CA794009.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii AY391432.12   -- 76.39(n)   386591  AY391432.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG92931 CG9293 61.23(n)
    59.41(a)    		   34752  NM_165042.2  NP_723814.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea ing-36
    Y43H11AL.16
    (see all 3)    		 Protein Y43H11AL.1, isoform a
    (see all 3)    		 9(a)
    6(a)
    (see all 3)    		 possible ortholog
    possible ortholog
    (see all 3)    		 II(13875962-13882515)
    II(222700-232741)
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes YNG21 Yng2p 45.34(n)
    30.51(a)    		   856490   NP_011958.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ING16
    ING26
    		 PHD finger protein-like protein
    		 27(a)
    13(a)
    		 possible ortholog
    1 ↔ many
    		 3(8675956-8678220)
    1(20304567-20307024)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 PHD-finger domain containing protein, putative, ex...
    PHD-finger domain containing protein, putative, ex...
    		 31(a)
    20(a)
    		 possible ortholog
    1 ↔ many
    		 3(2408857-2412428)
    3(30784503-30789908)


    ENSEMBL Gene Tree for ING5 (if available)
    TreeFam Gene Tree for ING5 (if available) 

    Paralogs
    for ING5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ING5 gene
    ING22  ING42  ING32  ING12  
    4 SIMAP similar genes for ING5 using alignment to 2 protein entries:     ING5_HUMAN (see all proteins):
    ING4    ING2    ING3    ING2b

    ING5 for paralogs           About GeneDecksing



    Genomic Variants
    for ING5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/560 NCBI SNPs in ING5 are shown (see all 560)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs797083351,2
    		C,--242639474(+) CTCACA/TGCAAC 1 -- us2k10--------
    rs794339531,2
    		C,--242639688(+) TGCCTG/CGGCCG 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs116958991,2
    		C,H,--242639842(+) GCTGGT/AATTAC 1 -- us2k11Minor allele frequency- A:0.00NA 4
    rs1918678311,2
    		--242639965(+) TCCCAA/GGCTCA 1 -- us2k10--------
    rs1839881511,2
    		--242640032(+) TGCCCG/TGCTAG 1 -- us2k10--------
    rs1893980011,2
    		--242640040(+) TAGTTG/TTTGTA 1 -- us2k10--------
    rs2002806721,2
    		--242640043(+) TTTTG-/TATTATTA 1 -- us2k10--------
    rs1460662011,2
    		--242640044(+) TTTTGC/TATTAT 1 -- us2k10--------
    rs621913121,2
    		--242640201(+) ACGCCA/CGGGTA 1 -- us2k10--------
    rs1809592071,2
    		--242640300(+) CCTCCC/TAAAGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ING5 (242641450 - 242668896 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for ING5
         3 CNVs: 34635 8969 34658

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    Disorders / Diseases
    for ING5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ING5 for disorders           About GeneDecksing

    OMIM gene information: 608525    OMIM disorders: --

    6 diseases for ING5:    About MalaCards
    oral squamous cell carcinoma    gastric diffuse adenocarcinoma    squamous cell carcinoma    huntington's disease
    carcinoma    adenocarcinoma

    Human Genome Epidemiology (HuGE) Navigator: ING5 (1 document)

    Export disorders for ING5 gene to outside databases

    Publications
    for ING5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ING5 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with ING5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. (PubMed id 12750254)1, 2, 3, 9 Shiseki M....Harris C.C. (2003)
    2. The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide. (PubMed id 18623064)1, 2 Champagne K.S....Kutateladze T.G. (2008)
    3. Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. (PubMed id 18794358)1, 2 Ullah M....Yang X.-J. (2008)
    4. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. (PubMed id 16728974)1, 2 Shi X....Gozani O. (2006)
    5. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. (PubMed id 16387653)1, 2 Doyon Y.... Cote J. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Conserved molecular interactions within the HBO1 acety ltransferase complexes regulate cell proliferation. (PubMed id 22144582)1 Avvakumov N....Cote J. (2012)
    10. MicroRNA-193 pro-proliferation effects for bone mesenc hymal stem cells after low-level laser irradiation treatment through inhibitor o f growth family, member 5. (PubMed id 22384930)1 Wang J....Zhang H. (2012)

    External Searches for ING5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
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    Genome Databases showing ING5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84289 HGNC: 19421 AceView: LOC401047 Ensembl:ENSG00000168395 euGenes: HUgn84289
    ECgene: ING5 H-InvDB: ING5

    Other Databases showing ING5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ING5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ING5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ING5 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for ING5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ING5 gene:
    Search GeneIP for patents involving ING5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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