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Aliases for INAFM1 Gene

Aliases for INAFM1 Gene

  • InaF Motif Containing 1 2 3 5
  • InaF-Motif-Containing Protein 1 3 4
  • Proline-Rich Protein 24 3 4
  • Proline Rich 24 2 3
  • PRR24 3 4
  • Putative Transmembrane Protein INAFM1 3

External Ids for INAFM1 Gene

Previous HGNC Symbols for INAFM1 Gene

  • PRR24

Summaries for INAFM1 Gene

GeneCards Summary for INAFM1 Gene

INAFM1 (InaF Motif Containing 1) is a Protein Coding gene.

Additional gene information for INAFM1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INAFM1 Gene

Genomics for INAFM1 Gene

Regulatory Elements for INAFM1 Gene

Enhancers for INAFM1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H047242 2.1 FANTOM5 Ensembl ENCODE dbSUPER 29.1 -30.6 -30612 2.5 ZFP64 DMAP1 YBX1 YY1 ZNF143 ZNF548 SP3 MCM3 ZC3H11A MEF2D ZC3H4 BICRA ENSG00000268810 NOP53-AS1 CCDC9 NOP53 ENSG00000269321 SLC1A5 INAFM1 SNORD23
GH19H047239 1.9 FANTOM5 Ensembl ENCODE dbSUPER 28.9 -33.8 -33843 3.1 HDGF PKNOX1 ARNT ZFP64 ARID4B YBX1 ZNF2 ZBTB7B ZNF207 ZNF548 ZC3H4 BICRA ENSG00000268810 NOP53 NOP53-AS1 CCDC9 INAFM1 ENSG00000268746 SLC1A5 EHD2
GH19H047105 1.9 FANTOM5 ENCODE dbSUPER 18.9 -164.1 -164106 9.2 MLX FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A ZC3H4 BICRA ENSG00000268810 C5AR2 PRKD2 CCDC9 NOP53-AS1 SNORD23 ENSG00000268746 DHX34
GH19H047225 1.5 ENCODE dbSUPER 20.3 -45.0 -45021 8.2 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 SP3 NFYC ZC3H4 BICRA ENSG00000268810 NOP53-AS1 CCDC9 NOP53 ENSG00000269321 PPP5D1 ENSG00000269124 SNORD23
GH19H047775 1.4 ENCODE dbSUPER 20 +504.3 504324 5.5 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 SELENOW ZC3H4 BICRA GRWD1 NOP53 INAFM1 NOP53-AS1 KDELR1 RPL18 CCDC9
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around INAFM1 on UCSC Golden Path with GeneCards custom track

Promoters for INAFM1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000110529 -202 2001 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766

Genomic Locations for INAFM1 Gene

Genomic Locations for INAFM1 Gene
chr19:47,274,402-47,275,723
(GRCh38/hg38)
Size:
1,322 bases
Orientation:
Plus strand
chr19:47,777,659-47,778,980
(GRCh37/hg19)

Genomic View for INAFM1 Gene

Genes around INAFM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INAFM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INAFM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INAFM1 Gene

Proteins for INAFM1 Gene

  • Protein details for INAFM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JVW0-INAM1_HUMAN
    Recommended name:
    Putative transmembrane protein INAFM1
    Protein Accession:
    C9JVW0

    Protein attributes for INAFM1 Gene

    Size:
    142 amino acids
    Molecular mass:
    14668 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INAFM1 Gene

Post-translational modifications for INAFM1 Gene

No Post-translational modifications

Other Protein References for INAFM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for INAFM1 Gene

Domains & Families for INAFM1 Gene

Gene Families for INAFM1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for INAFM1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for INAFM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with INAFM1: view

No data available for UniProtKB/Swiss-Prot for INAFM1 Gene

Function for INAFM1 Gene

Phenotypes From GWAS Catalog for INAFM1 Gene

Phenotypes for INAFM1 Gene

GenomeRNAi human phenotypes for INAFM1:
genes like me logo Genes that share phenotypes with INAFM1: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INAFM1 Gene

Localization for INAFM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for INAFM1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for INAFM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with INAFM1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for INAFM1 Gene

Pathways & Interactions for INAFM1 Gene

SuperPathways for INAFM1 Gene

No Data Available

Interacting Proteins for INAFM1 Gene

Gene Ontology (GO) - Biological Process for INAFM1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for INAFM1 Gene

Drugs & Compounds for INAFM1 Gene

No Compound Related Data Available

Transcripts for INAFM1 Gene

mRNA/cDNA for INAFM1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for INAFM1 Gene

No ASD Table

Relevant External Links for INAFM1 Gene

GeneLoc Exon Structure for
INAFM1
ECgene alternative splicing isoforms for
INAFM1

Expression for INAFM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for INAFM1 Gene

Protein differential expression in normal tissues from HIPED for INAFM1 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for INAFM1 Gene



Protein tissue co-expression partners for INAFM1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of INAFM1 Gene:

INAFM1
genes like me logo Genes that share expression patterns with INAFM1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INAFM1 Gene

Orthologs for INAFM1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for INAFM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRR24 33 34
  • 98.59 (n)
dog
(Canis familiaris)
Mammalia PRR24 33
  • 84.98 (n)
rat
(Rattus norvegicus)
Mammalia Prr24 33
  • 72.66 (n)
mouse
(Mus musculus)
Mammalia Prr24 33 34
  • 69.74 (n)
Inafm1 16
Species where no ortholog for INAFM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for INAFM1 Gene

ENSEMBL:
Gene Tree for INAFM1 (if available)
TreeFam:
Gene Tree for INAFM1 (if available)

Paralogs for INAFM1 Gene

No data available for Paralogs for INAFM1 Gene

Variants for INAFM1 Gene

Sequence variations from dbSNP and Humsavar for INAFM1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000820712 -- 47,275,085(+) TCTGG(A/G)TACCC nc-transcript-variant, reference, missense
rs1000936321 -- 47,275,179(+) CCCGG(A/C/T)GCCCG nc-transcript-variant, reference, missense
rs1001696872 -- 47,273,166(+) TATGT(C/T)GGGAG upstream-variant-2KB
rs1001992971 -- 47,274,064(+) CCAGG(C/T)TGTGT upstream-variant-2KB
rs1002369923 -- 47,274,470(+) AGGGC(G/T)CGAGC nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for INAFM1 Gene

Variant ID Type Subtype PubMed ID
nsv833852 CNV loss 17160897
nsv1143920 CNV deletion 24896259
nsv1071542 CNV deletion 25765185
nsv1067417 CNV gain 25217958
nsv1059583 CNV loss 25217958
esv3893225 CNV loss 25118596

Variation tolerance for INAFM1 Gene

Gene Damage Index Score: 7.06; 80.34% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for INAFM1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INAFM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for INAFM1 Gene

Disorders for INAFM1 Gene

Relevant External Links for INAFM1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
INAFM1

No disorders were found for INAFM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for INAFM1 Gene

Publications for INAFM1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 60
  3. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60

Products for INAFM1 Gene

Sources for INAFM1 Gene

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