INADL Gene
protein-coding GIFtS: 54
GCID: GC01P062208
|
|
InaD-like (Drosophila)
| |
Aliases for INADL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| InaD-Like (Drosophila)1 2 | | InaD-Like1 | | PATJ1 2 3 5 | | Channel-Interacting PDZ Domain Protein2 | | Cipp1 2 | | Inactivation No After-Potential D-Like Protein2 | | Pals1-Associated Tight Junction Protein2 3 | | InaD-Like Protein2 | | Protein Associated To Tight Junctions2 3 | | PDZ Domain Protein2 | | HINADL1 | | Inadl Protein3 |
Export aliases for INADL gene to outside databasesPrevious GC identifers: GC01P062141 GC01P061131 GC01P061565 GC01P061578 GC01P061920 GC01P060320 |
Summaries for INADL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for INADL: This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteinswith multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tightjunctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding proteinwhich tethers several members of a multimeric signaling complex in photoreceptors. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: INADL_HUMAN, Q8NI35Function: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. Mayregulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/orfunction of ASIC3 in sensory neurons Gene Wiki entry for INADL
|
Genomic Views for INADL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the INADL gene promoter: LHX3b/Lhx3b Elk-1 Nkx2-2 GATA-1 CREB IRF-2 Pax-3 GATA-6 LHX3a/Lhx3a Pax-4a Other transcription factors
Search SABiosciences Chromatin IP Primers for INADL
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INADL |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p31.3 Ensembl cytogenetic band: 1p31.3 HGNC cytogenetic band: 1p31INADL Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P062208: view genomic region
(about GC identifiers)
Start:
|
62,208,149 bp from pter |
End:
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62,629,592 bp from pter |
Size:
|
421,444 bases |
Orientation:
|
plus strand |
|
Proteins for INADL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: INADL_HUMAN, Q8NI35 (See
protein sequence)Recommended Name: InaD-like protein Size: 1801 amino acids; 196368 Da
Subunit: Interacts with ASIC3, KCNJ10, KCNJ15, GRIN2A, GRIN2B, GRIN2C, GRIN2D, NLGN2, MPP7, HTR2A and SLC6A4 (Bysimilarity). Forms a ternary complex with MPP5, CRB1 and CRB3. Interacts with TJP3/ZO-3 and CLDN1/claudin-1. Componentof a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Directly interacts withHTR4 (By similarity). Interacts (via PDZ domain 8) with WWC1 (via the ADDV motif)
Subcellular location: Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region.Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes totight junctions in epithelial cells. Also found at the apical plasma membrane
Sequence caution: Sequence=CAH70416.1; Type=Erroneous gene model prediction; Sequence=CAI21733.1; Type=Erroneous genemodel prediction; Sequence=CAI22258.1; Type=Erroneous gene model prediction;
6/8 PDB 3D structures from and Proteopedia for INADL (see all 8):1VF6 (3D)
  2D92 (3D)
  2DAZ (3D)
  2DB5 (3D)
  2DLU (3D)
  2DM8 (3D)
 
Secondary accessions: O15249 O43742 O60833 Q5VUA5 Q5VUA6 Q5VUA7 Q5VUA8 Q5VUA9 Q5VUB0 Q8WU78 Q9H3N9Alternative splicing: 5 isoforms: Q8NI35-1 Q8NI35-2 Q8NI35-3 Q8NI35-4 Q8NI35-5 Explore the universe of human proteins at neXtProt for INADL: NX_Q8NI35
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NI35 INADL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_795352.2 ENSEMBL proteins: ENSP00000360200 ENSP00000326199 ENSP00000433669 ENSP00000307496 ENSP00000445790 ENSP00000440094 Reactome Protein details: Q8NI35 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
INADL for ontologies About GeneDecksing
INADL Antibody Products: Assay Products for INADL: |
Protein
Domains / Families for INADL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
INADL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NI35ProtoNet protein and cluster: Q8NI35 1 Blocks protein family: IPB001478 PDZ/DHR/GLGF domain
UniProtKB/Swiss-Prot: INADL_HUMAN, Q8NI35Domain: The L27 domain (also called Maguk recruitment domain) is required for interaction with MPP5 and CRB3, and MPP5localization to tight junctionsDomain: The PDZ domain 6 mediates interaction with the C-terminus of TJP3 and is crucial for localization to the tightjunctions. The PDZ domain 8 interacts with CLDN1 but is not required for proper localizationSimilarity: Contains 1 L27 domainSimilarity: Contains 10 PDZ (DHR) domains |
Function for INADL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: INADL_HUMAN, Q8NI35Function: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. Mayregulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/orfunction of ASIC3 in sensory neurons
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INADL (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INADL (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: INADL (NM_176877) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for INADL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INADL  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INADL |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
INADL for ontologies About GeneDecksing
|
Pathways & Interactions for INADL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell-cell junction organization | | | 2 | Tight junction | | | 3 | Sertoli-Sertoli Cell Junction Dynamics | |
Pathway sources See GeneCards unified pathways Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for INADL 4
Reactome Pathways for INADL
1
Kegg Pathway (Kegg details for INADL):
INADL for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for INADL
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/67 Interacting proteins for INADL (Q8NI351, 2, 3 ENSP000003602004) via UniProtKB, MINT, STRING, and/or I2D (see all 67)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| DDX18 | Q9NVP12, 3, ENSP000002632394 | MINT-65643 I2D:
score=3 STRING: ENSP00000263239 | | MPP5 | Q8N3R92, 3, ENSP000002616814 | MINT-1774417 MINT-1774200 MINT-2843240 I2D:
score=2 STRING: ENSP00000261681 | | TJP3 | O950492, 3, ENSP000002629684 | MINT-58720 MINT-58722 MINT-58721 I2D:
score=2 STRING: ENSP00000262968 | | CRB1 | P822792, 3, ENSP000003563704 | MINT-1774293 MINT-1774377 I2D:
score=1 STRING: ENSP00000356370 | | F2RL2 | O002542, 3, ENSP000002966414 | MINT-4300898 MINT-4300885 I2D:
score=1 STRING: ENSP00000296641 | About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
INADL for ontologies About GeneDecksing
|
Drugs & Compounds for INADL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
INADL for compounds About GeneDecksing
Browse Tocris compounds for INADL 6 Novoseek chemical compound relationships for INADL gene About this table
Search CenterWatch for drugs/clinical trials and news about INADL 
|
Transcripts for INADL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for INADL gene (3 alternative transcripts): NM_176877.2 NM_005799.2 NM_176878.1 Unigene Cluster for INADL: InaD-like (Drosophila) Hs.478125 [show with all ESTs]Unigene Representative Sequence: NM_17687714 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371158(uc001dab.3 uc009wag.3) ENST00000484562(uc001dad.3) ENST00000316485(uc009waf.1) ENST00000459752(uc001daa.2 uc010oou.1) ENST00000484937(uc001dac.3) ENST00000488913 ENST00000493967 ENST00000494842 ENST00000490547 ENST00000307297 ENST00000465798 ENST00000472512 ENST00000543708(uc010oot.2) ENST00000545929
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INADL (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INADL (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: INADL (NM_176877) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for INADL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INADL  |
Additional cDNA sequence: AF397170.1 AJ001306.1 AJ224747.1 AJ224748.1 AK293519.1 AK294187.1 AK304355.1 AK307713.1 AK308428.1 AK308665.1 BC021135.1 BC142661.1 BC142723.1 BC144135.1 18 DOTS entries: DT.110720 DT.100781932 DT.121419068 DT.97789417 DT.70104727 DT.119248 DT.100721371 DT.97833684 DT.121419091 DT.40314090 DT.97789428 DT.75154718 DT.75192209 DT.91674136 DT.91748005 DT.95362168 DT.40250926 DT.75189274 24/155 AceView cDNA sequences (see all 155): AI392921 CD356816 BE392595 AI697184 BQ439979 AW305081 NM_005799 NM_176877 AI765784 AA777657 BE501835 BF331554 BU678903 AJ224747 AI601105 BF475257 AA843633 AU132556 NM_176878 NM_170605 BE073934 CB047676 AA357999 AJ224748 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for INADL (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 27 | ^ | 28 | ^ | 29a | · | 29b | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38a | · | 38b | ^ | 39 | ^ | 40 | ^ | 41 | ^ | 42 | ^ | 43 | ^ | 44 | ^ | 45 | ^ | 46 | ^ | 47 | |
| SP1: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for INADL
|
Expression for INADL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| INADL expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See INADL Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for INADL
SOURCE GeneReport for Unigene cluster: Hs.478125 UniProtKB/Swiss-Prot: INADL_HUMAN, Q8NI35Tissue specificity: Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas andcerebellum in the brain SABiosciences Expression via Pathway-Focused PCR Array including INADL:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INADL Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat INADL | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INADL | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INADL | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INADL |
Orthologs for INADL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for INADL gene from 6/20 species (see all 20) About this table
ENSEMBL Gene Tree for INADL (if available) TreeFam Gene Tree for INADL (if available)  |
Paralogs for INADL gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for INADL gene
- PARD3B2 PDZD22 IL162 PARD32 LNX22 MPDZ2 LNX12
6 SIMAP similar genes for INADL using alignment to 4 protein entries: INADL_HUMAN (see all proteins):DLG4 TJP2 MPDZ ARHGAP23 SYNJ2BP DLG2
INADL for paralogs About GeneDecksing
|
Genomic Variants for INADL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for INADL (62208149 - 62458149 bp, first 250kb of INADL)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 20 variations for INADL 11 CNVs: 1002 63907 34827 1001 48347 84279 31625 1542 48349 9884 48348 9 Indels: 11398 97371 97370 44600 42393 60829 39609 63899 24238  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INADL |
|
Disorders
/ Diseases for INADL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
INADL for disorders About GeneDecksing
OMIM gene information: 603199
OMIM disorders: --
10 diseases for INADL: About MalaCardsleber congenital amaurosis bullous pemphigoid retinal degeneration cystic fibrosis fibrosis retinitis cervical cancer cervicitis pharyngitis neuronitis
3 Novoseek disease relationships for INADL gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| retinal degeneration |
29.1 |
1 |
15755798 (1) |
| cystic fibrosis |
9.81 |
1 |
11707463 (1) |
| tumors |
0 |
2 |
19015633 (1) |
Human Genome Epidemiology (HuGE) Navigator: INADL (1 document) Export disorders for INADL gene to outside databases
|
Publications for INADL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for INADL gene, integrated from 9 sources (see all 116): (articles sorted by number of sources associating them with INADL) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular characterization of a novel PDZ domain protein with homology to INAD from Drosophila melanogaster. (PubMed id 9280290)1, 2, 3, 9 Philipp S. and Flockerzi V. (1997)
- Isolation of novel heart-specific genes using the BodyMap database. (PubMed id 11374908)1, 2, 3 Soejima H.... Mukai T. (2001)
- The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. (PubMed id 11927608)1, 2, 9 Roh M.H.... Margolis B. (2002)
- KIBRA modulates directional migration of podocytes. (PubMed id 18596123)1, 2 Duning K.... Pavenstaedt H. (2008)
- A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. (PubMed id 16678097)1, 2 Wells C.D.... Pawson T. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes. (PubMed id 15241471)1, 2 Li Y.... Lavie A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions. (PubMed id 12021270)1, 2 Roh M.H.... Margolis B. (2002)
- hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells. (PubMed id 11964389)1, 2 Lemmers C....Le Bivic A. (2002)
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External Searches for INADL gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing INADL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing INADL gene
(According to HUGE)
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Specialized Databases showing INADL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for INADL | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for INADL gene: Search GeneIP for patents involving INADL
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for INADL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for INADL | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for INADL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INADL | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for INADL | | OriGene 3'-UTR Clone for INADL | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INADL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INADL | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for INADL | | OriGene Custom Protein Services for INADL | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat INADL | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INADL | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INADL | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat INADL | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INADL | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INADL |
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 | | INADL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INADL |
|  |  |  | | | Search ThermoFisher Antibodies for INADL |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INADL |
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