Aliases for INA Gene
External Ids for INA Gene
Previous HGNC Symbols for INA Gene
Previous GeneCards Identifiers for INA Gene
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009]
GeneCards Summary for INA Gene
INA (Internexin Neuronal Intermediate Filament Protein Alpha) is a Protein Coding gene. Diseases associated with INA include Wernicke Encephalopathy and Medulloepithelioma. Among its related pathways are Cytoskeleton remodeling Neurofilaments. Gene Ontology (GO) annotations related to this gene include structural molecule activity and structural constituent of cytoskeleton. An important paralog of this gene is NEFL.
UniProtKB/Swiss-Prot for INA Gene
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.