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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

IMPG2 Gene

protein-coding GIFtS: 50
GCID: GC03M100944

interphotoreceptor matrix proteoglycan 2

Explore 7 diseases affiliated with
IMPG2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Interphotoreceptor Matrix Proteoglycan 2¹ ²		RP56² ⁵
IPM200¹ ² ³ ⁵		SPACRCAN²
Interphotoreceptor Matrix Proteoglycan Of 200 KDa² ³		Interphotoreceptor Matrix Proteoglycan IPM 200²
Sialoprotein Associated With Cones And Rods Proteoglycan² ³		Spacrcan³
IPM 200² ³

External Ids:	HGNC: 18362¹	Entrez Gene: 50939²	Ensembl: ENSG00000081148⁷	OMIM: 607056⁵	UniProtKB: Q9BZV3³

Export aliases for IMPG2 gene to outside databases

Previous GC identifers: GC03M097598 GC03M100372 GC03M102226 GC03M102266 GC03M102428 GC03M098313

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IMPG2:

The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein

plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the

light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and

maculopathy, IMPG2-related.(provided by RefSeq, Mar 2011)

UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3

Function: Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor

matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds

heparin

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IMPG2 gene promoter:
Oct-B1 E2F-3a E2F-4 E2F-5 oct-B2 E2F-2 E2F E2F-1 POU2F1 POU2F1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IMPG2 promoter sequence

Search SABiosciences Chromatin IP Primers for IMPG2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IMPG2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12.2-q12.3 Ensembl cytogenetic band: 3q12.3 HGNC cytogenetic band: 3q12.2-q12.3

IMPG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IMPG2 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M100944: view genomic region (about GC identifiers)

Start:	100,945,288 bp from pter	End:	101,039,419 bp from pter
Size:	94,132 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3 (See protein sequence)

Recommended Name: Interphotoreceptor matrix proteoglycan 2 precursor

Size: 1241 amino acids; 138621 Da

Subcellular location: Membrane; Single-pass type I membrane protein (Potential)

Secondary accessions: A8MWT5 Q9UKD4 Q9UKK5

Explore the universe of human proteins at neXtProt for IMPG2: NX_Q9BZV3

Post-translational modifications:

Highly glycosylated (N- and O-linked carbohydrates)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BZV3

IMPG2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057331.2

ENSEMBL proteins:

ENSP00000193391

Human Recombinant Protein Products:

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	Uscn Proteins for IMPG2

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005578	proteinaceous extracellular matrix	TAS	10702256
GO:0016021	integral to membrane	IEA	--

IMPG2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for IMPG2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IMPG2 for domains About GeneDecksing

3 InterPro domains/families:

IPR000082 SEA

IPR000742 EG-like_dom

IPR013032 EGF-like_CS

Graphical View of Domain Structure for InterPro Entry Q9BZV3

ProtoNet protein and cluster: Q9BZV3

1 Blocks protein family: IPB000082 SEA domain

UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3

Similarity: Contains 2 EGF-like domains

Similarity: Contains 2 SEA domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3

Function: Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor

matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds

heparin

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IMPG2
		8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate IMPG2 (see all 52):
		hsa-miR-607 hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-let-7d hsa-miR-488 hsa-miR-570 hsa-let-7g

		SwitchGear 3'UTR luciferase reporter plasmid: IMPG2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IMPG2 (see all 7) OriGene shRNA RFP: IMPG2 OriGene siRNA: IMPG2
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPG2

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	--	--
GO:0005201	extracellular matrix structural constituent	TAS	10702256
GO:0005540	hyaluronic acid binding	TAS	10702256
GO:0008201	heparin binding	IEA	--

IMPG2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for IMPG2:

Decreased POU5F1-GFP protein e

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Integrin Pathway

Integrin Pathway	1.00	UPA-UPAR Pathway	0.51
FAK1 Signaling	0.67	Transendothelial Migration of Leukocytes	0.38
GnRH Signaling	0.56	Inhibition of Angiogenesis by TSP1	0.37

Rho Family GTPases

Rho Family GTPases	1.00	MAPK Signaling	0.51
ERK Signaling	0.61	ILK Signaling	0.45
Molecular Mechanisms of Cancer	0.51

PTEN Pathway

PTEN Pathway

1.00

Phospholipase-C Pathway

0.56

5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IMPG2 (see all 13)

	MAPK Signaling
	Molecular Mechanisms of Cancer
	PTEN Pathway
	Transendothelial Migration of Leukocytes
	UPA-UPAR Pathway

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for IMPG2

1 Interacting protein for IMPG2 (Q9BZV3³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PPP2CA	P67775³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007601	visual perception	TAS	10702256

IMPG2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IMPG2

1 HMDB Compound for IMPG2 About this table

Compound	Synonyms	CAS #	PubMed Ids
Hyaluronan	hyaluronic acid (see all 13)	9004-61-9	--

Search CenterWatch for drugs/clinical trials and news about IMPG2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IMPG2 gene:

NM_016247.3

Unigene Cluster for IMPG2:

Interphotoreceptor matrix proteoglycan 2

Hs.209249 [show with all ESTs]

Unigene Representative Sequence: NM_016247

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000193391(uc011bhe.2 uc003duq.2 uc010hpj.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IMPG2
		8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate IMPG2 (see all 52):
		hsa-miR-607 hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-let-7d hsa-miR-488 hsa-miR-570 hsa-let-7g

		SwitchGear 3'UTR luciferase reporter plasmid: IMPG2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IMPG2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IMPG2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IMPG2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: IMPG2 (NM_016247)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IMPG2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IMPG2

Additional cDNA sequence:

AB593127.1 AF157624.1 AF173155.1 AF319972.1 BC144092.1

5 DOTS entries:

DT.101955084 DT.97839976 DT.95189990 DT.425499 DT.100739143

24/35 AceView cDNA sequences (see all 35):

BX510203 BX953412 BM799621 AL713046 BX642541 AF173155 BU167472 BX953290

AA736980 BX953286 BM929973 NM_016247 AL712421 BX283908 BX954997 AF157624

BX491222 BX509854 AA721009 BX953550 AA364834 AA744481 AA815118 AF319972

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IMPG2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAAGTCTG

About this image
See IMPG2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IMPG2

SOURCE GeneReport for Unigene cluster: Hs.209249

UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3

Tissue specificity: Expressed in the retina. Expressed by photoreceptors of the interphotoreceptor matrix (IPM)

surrounding both rods and cones. IPM occupies the subretinal space between the apices of the retinal pigment

epithelium and the neural retina. Detected in the pineal gland

SABiosciences Custom PCR Arrays for IMPG2

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for IMPG2 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Impg2^{1 , 5}	interphotoreceptor matrix proteoglycan 2^{1, 5}	81.46(n)¹ 72.73(a)¹		16 (33.91 cM)⁵ 224224¹ NM_174876.3¹ NP_777365.2¹ 56204313⁵
chicken (Gallus gallus)	Aves	IMPG2¹	interphotoreceptor matrix proteoglycan 2	61.76(n) 52.41(a)		418393 NM_001044639.1 NP_001038104.1
lizard (Anolis carolinensis)	Reptilia	IMPG2⁶	--	46(a)	1 ↔ 1	3(173699864-173771539)
zebrafish (Danio rerio)	Actinopterygii	impg2⁶ si:ch211-88n13.3⁶ (see all 4)	si:ch211-88n13.3 (see all 4)	67(a) 36(a) (see all 4)	many → 1 many → 1 (see all 4)	22(30302867-30339587) 9(31213330-31226051)

ENSEMBL Gene Tree for IMPG2 (if available)
TreeFam Gene Tree for IMPG2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for IMPG2 gene

IMPG1²

1 SIMAP similar gene for IMPG2 using alignment to 3 protein entries: IMPG2_HUMAN (see all proteins):

DKFZp686K0887

IMPG2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs201893545^1,2	C	pathogenic	136948402(+)	`CCAAAA/GAGTCC`	2	L F	mis¹		0	--	--	--	--
rs116713708^1,2	C,F,	--	98309666(+)	`TTTATT/GTCTTC`	1	--	ds500¹		1		WA	118
rs59652222^1,2	C,F,	--	98309701(+)	`CATTTC/TGCCTC`	1	--	ds500¹		5		WA NA	244
rs58676554^1,2	C,F,	--	98309778(+)	`TTCCAT/GTCCTA`	1	--	ds500¹		4		WA CSA	124
rs11928016^1,2	H	--	98309965(+)	`AAAGAC/TTTTCA`	1	--	ds500¹		0	--	--	--	--
rs112062476^1,2	C,F,	--	98311452(+)	`GATCAC/TCTGAG`	1	--	ut3¹		2		WA CSA	4
rs61360259^1,2	C	--	98311538(+)	`TGGGCG/ATGGTG`	1	--	ut3¹		1		WA	2
rs77671634^1,2	C,	--	98311616(+)	`AGGTTG/TCCAGG`	1	--	ut3¹		1		WA	2
rs78391139^1,2	F,	--	98311843(+)	`TACATC/ATGTAA`	1	--	ut3¹		1		NA	120
rs112670504^1,2		--	98311848(+)	`CTGTAG/AAACAC`	1	--	ut3¹		1		CSA	1

HapMap Linkage Disequilibrium report for IMPG2 (100945288 - 101039419 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IMPG2: --
Human Gene Mutation Database (HGMD): IMPG2

Locus Specific Mutation Databases (LSDB): IMPG2

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IMPG2

DNA2.0 Custom Variant and Variant Library Synthesis for IMPG2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

IMPG2 for disorders           About GeneDecksing

OMIM gene information: 607056
OMIM disorders: 613581
UniProtKB/Swiss-Prot: IMPG2_HUMAN, Q9BZV3

Defects in IMPG2 are the cause of retinitis pigmentosa type 56 (RP56) [MIM:613581]. RP56 is a retinal

dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment

deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone

photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their

condition progresses, they lose their far peripheral visual field and eventually central vision as well

Defects in IMPG2 are the cause of maculopathy IMPG2-related (MACLP-IMPG2) [MIM:613581]. MACLP-IMPG2 is a mild

maculopathy characterized by full-field electroretinogram responses within normal limits, normal color vision,

elevation of the photoreceptor layer in the foveal region and mild nuclear sclerosis

7 diseases for IMPG2: About MalaCards

retinitis pigmentosa maculopathy age related macular degeneration retinitis

macular degeneration pigmentary retinopathy blindness

Human Genome Epidemiology (HuGE) Navigator: IMPG2 (1 document)

Export disorders for IMPG2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for IMPG2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IMPG2)

Utopia: connect your pdf to the dynamic
world of online information

Molecular characterization and genomic mapping of human IPM 200, a second member of a novel family of proteoglycans. (PubMed id 10542133)^{1, 2, 3} Kuehn M.H. and Hageman G.S. (1999)
SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes. (PubMed id 10702256)^{1, 2, 9} Acharya S.... Hollyfield J.G. (2000)
Organization of the human IMPG2 gene and its evaluation as a candidate gene in age-related macular degeneration and other retinal degenerative disorders. (PubMed id 11726612)^{1, 2, 9} Kuehn M.H.... Hageman G.S. (2001)
Mutations in IMPG2, encoding interphotoreceptor matri x proteoglycan 2, cause autosomal-recessive retinitis pigmentosa. (PubMed id 20673862)^{1, 2} Bandah-Rozenfeld D....den Hollander A.I. (2010)
Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)¹ Oshikawa M.... Kato S. (2011)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)¹ Bonaldo M.F.... Soares M.B. (1996)
Retinitis Pigmentosa Overvi ew (PubMed id 20301590)¹ Pagon R.A. and Daiger S.P. (1993)
SPACRCAN in the interphotoreceptor matrix of the mouse retina: molecular, developmental and promoter analysis. (PubMed id 12589770)⁹ Chen Q....Hollyfield J.G. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 50939	HGNC: 18362	AceView: IMPG2	Ensembl:ENSG00000081148	euGenes: HUgn50939
ECgene: IMPG2	H-InvDB: IMPG2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for IMPG2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for IMPG2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for IMPG2 gene:
Search GeneIP for patents involving IMPG2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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IMPG2 Gene

interphotoreceptor matrix proteoglycan 2

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IMPG2 Gene

interphotoreceptor matrix proteoglycan 2

Aliasesfor IMPG2 gene

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for IMPG2 gene

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for IMPG2 gene

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for IMPG2 gene

Function
for IMPG2 gene

Pathways & Interactions
for IMPG2 gene

Drugs & Compounds
for IMPG2 gene

Transcripts
for IMPG2 gene

Expression
for IMPG2 gene

Orthologs
for IMPG2 gene

Paralogs
for IMPG2 gene

Genomic Variants
for IMPG2 gene

Disorders / Diseases
for IMPG2 gene

Publications
for IMPG2 gene

Intellectual Property
for IMPG2 gene

Products
for IMPG2 gene