Aliases for IMPG2 Gene
External Ids for IMPG2 Gene
Previous GeneCards Identifiers for IMPG2 Gene
The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.[provided by RefSeq, Mar 2011]
GeneCards Summary for IMPG2 Gene
IMPG2 (Interphotoreceptor Matrix Proteoglycan 2) is a Protein Coding gene. Diseases associated with IMPG2 include Macular Dystrophy, Vitelliform, 5 and Retinitis Pigmentosa 56. Among its related pathways are ERK Signaling and Phospholipase-C Pathway. GO annotations related to this gene include heparin binding and hyaluronic acid binding. An important paralog of this gene is IMPG1.
UniProtKB/Swiss-Prot for IMPG2 Gene
Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.