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IMPG1 Gene

protein-coding   GIFtS: 54
GCID: GC06M076687

Interphotoreceptor Matrix Proteoglycan 1

(Previous name: sialoprotein associated with cones and rods)
(Previous symbol: SPACR)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interphotoreceptor Matrix Proteoglycan 11 2     Interphotoreceptor Matrix Proteoglycan Of 150 KDa2 3
Sialoprotein Associated With Cones And Rods1 2 3     GP1472
SPACR1 2 3     IPM-1503
IPM1502 3 5     

External Ids:    HGNC: 60551   Entrez Gene: 36172   Ensembl: ENSG000001127067   OMIM: 6028705   UniProtKB: Q17R603   

Export aliases for IMPG1 gene to outside databases

Previous GC identifers: GC06M076578 GC06M076626 GC06M073829


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IMPG1 Gene:
This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded
protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in
adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple
transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for IMPG1 Gene:
IMPG1 (interphotoreceptor matrix proteoglycan 1) is a protein-coding gene. Diseases associated with IMPG1 include progressive bifocal chorioretinal atrophy, and benign concentric annular macular dystrophy. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is IMPG2.

UniProtKB/Swiss-Prot: IMPG1_HUMAN, Q17R60
Function: May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the
insoluble interphotoreceptor matrix

Gene Wiki entry for IMPG1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_025741.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the IMPG1 gene promoter:
         NF-1/L   NF-1   Nkx2-2   Lmo2   FOXO3   POU3F2   FOXL1   FOXO3b   FAC1   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIMPG1 promoter sequence
   Search Chromatin IP Primers for IMPG1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IMPG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14.2-q15   Ensembl cytogenetic band:  6q14.1   HGNC cytogenetic band: 6q14.2-q15

IMPG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IMPG1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M076687:  view genomic region     (about GC identifiers)

Start:
76,630,832 bp from pter      End:
76,782,395 bp from pter
Size:
151,564 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IMPG1_HUMAN, Q17R60 (See protein sequence)
Recommended Name: Interphotoreceptor matrix proteoglycan 1 precursor  
Size: 797 amino acids; 89387 Da
Secondary accessions: A6NNZ6 O43686 O95094 Q9BWZ1

Explore the universe of human proteins at neXtProt for IMPG1: NX_Q17R60

Explore proteomics data for IMPG1 at MOPED

Post-translational modifications: 

  • The N-terminus is blocked1
  • Highly glycosylated (N- and O-linked carbohydrates and sialic acid)1
  • Glycosylation2 at Asn42, Asn143, Asn191, Asn215, Thr403, Thr421, Thr432, Thr442, Asn592, Asn616,
                                 Asn630, Asn648
  • Modification sites at PhosphoSitePlus

  • See IMPG1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001269297.1  NP_001554.2  

    ENSEMBL proteins: 
     ENSP00000358966   ENSP00000358968   ENSP00000358980  

    IMPG1 Human Recombinant Protein Products:

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    Novus Biologicals IMPG1 Lysate
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    Cloud-Clone Corp. Proteins for IMPG1

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for IMPG1
    Cloud-Clone Corp. CLIAs for IMPG1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR000082 SEA_dom

    Graphical View of Domain Structure for InterPro Entry Q17R60

    ProtoNet protein and cluster: Q17R60

    1 Blocks protein domain: IPB000082 SEA domain

    UniProtKB/Swiss-Prot: IMPG1_HUMAN, Q17R60
    Similarity: Contains 2 SEA domains


    IMPG1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IMPG1_HUMAN, Q17R60
    Function: May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the
    insoluble interphotoreceptor matrix

         Genatlas biochemistry entry for IMPG1:
    interphotoreceptor matrix,not chondroitin 6-sulfate proteoglycan 1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent TAS9691169
    GO:0005515protein binding ----
         
    IMPG1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IMPG1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IMPG1

    miRNA
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    miRTarBase miRNAs that target IMPG1:
    hsa-mir-26b-5p (MIRT028838)

    Block miRNA regulation of human, mouse, rat IMPG1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate IMPG1:
    hsa-miR-3650 hsa-miR-943
    SwitchGear 3'UTR luciferase reporter plasmidIMPG1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IMPG1
    Predesigned siRNA for gene silencing in human, mouse, rat IMPG1

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IMPG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IMPG1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPG1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IMPG1_HUMAN, Q17R60: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular4
    plasma membrane3
    nucleus2
    cytosol1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix TAS9691169

    IMPG1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IMPG1 About    
    See pathways by source

    SuperPathContained pathways About
    1Integrin Pathway
    FAK1 Signaling0.67
    UPA-UPAR Pathway0.56
    Integrin Pathway0.67
    Inhibition of Angiogenesis by TSP10.50
    GnRH Signaling0.56
    Transendothelial Migration of Leukocytes0.38
    2ERK Signaling
    Rho Family GTPases0.61
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    ILK Signaling0.49
    MAPK Signaling0.58
    3Phospholipase-C Pathway
    Phospholipase-C Pathway0.56
    PTEN Pathway0.56

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IMPG1 (see all 13)
        MAPK Signaling
    Molecular Mechanisms of Cancer
    PTEN Pathway
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IMPG1
    Interactions:

        Search GeneGlobe Interaction Network for IMPG1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007601visual perception TAS9691169

    IMPG1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IMPG1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IMPG1 gene (2 alternative transcripts): 
    NM_001282368.1  NM_001563.3  

    Unigene Cluster for IMPG1:

    Interphotoreceptor matrix proteoglycan 1
    Hs.590893  [show with all ESTs]
    Unigene Representative Sequence: CR749572
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369950(uc003pik.1) ENST00000369952 ENST00000369963
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IMPG1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate IMPG1:
    hsa-miR-3650 hsa-miR-943
    SwitchGear 3'UTR luciferase reporter plasmidIMPG1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat IMPG1
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    GenScript: all cDNA clones in your preferred vector: IMPG1 (NM_001563)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IMPG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IMPG1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IMPG1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IMPG1
      QuantiTect SYBR Green Assays in human, mouse, rat IMPG1
      QuantiFast Probe-based Assays in human, mouse, rat IMPG1

    Additional mRNA sequence: 

    AF047492.2 BC117450.1 BC117452.1 CR749572.1 DQ426878.1 

    3 DOTS entries:

    DT.99974829  DT.209981  DT.97838023 

    Selected AceView cDNA sequences (see all 35):

    NM_001563 BU728582 BM663753 AF047492 AV656968 AA326863 BM695987 CA391789 
    BX097138 BQ639265 BU726282 BU729227 BM690735 BU731220 BX646053 BI752112 
    BU732814 CR749572 AL713229 BM691879 BX510244 BM726533 BQ638902 BU734170 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IMPG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAAATCTT
    IMPG1 Expression
    About this image


    IMPG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             Mature Rod Cells Outer Nuclear Layer
             Retina
     
     Neurons
             Mature Rod Cells Outer Nuclear Layer
    IMPG1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IMPG1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.590893

    UniProtKB/Swiss-Prot: IMPG1_HUMAN, Q17R60
    Tissue specificity: Abundantly expressed in retina where it is specifically expressed by cone and rod
    photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of
    the retina

        Custom PCR Arrays for IMPG1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPG1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IMPG1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Impg11 , 5 interphotoreceptor matrix proteoglycan 11, 5 77.74(n)1
    67.05(a)1
      9 (43.99 cM)5
    638591  NM_022016.31  NP_071299.31 
     803139955 
    chicken
    (Gallus gallus)
    Aves IMPG11 interphotoreceptor matrix proteoglycan 1 64.16(n)
    55.54(a)
      374088  NM_204241.1  NP_989572.1 
    lizard
    (Anolis carolinensis)
    Reptilia IMPG16
    interphotoreceptor matrix proteoglycan 1
    67(a)
    1 ↔ 1
    1(200996464-201021968)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.139052 Transcribed sequence with weak similarity to protein more 74.63(n)    BX743511.1 
    zebrafish
    (Danio rerio)
    Actinopterygii impg1b6
    impg1a6
    interphotoreceptor matrix proteoglycan 1a
    27(a)
    21(a)
    1 ↔ many
    1 ↔ many
    17(36794617-36849258) ENSDARG00000074839
    20(801600-832111) ENSDARG00000077187


    ENSEMBL Gene Tree for IMPG1 (if available)
    TreeFam Gene Tree for IMPG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IMPG1 gene
    IMPG22  

    IMPG1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IMPG1 (see all 3237)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1932000941,2
    --76630613(+) TGACCC/TACCTG 1 -- ds50010--------
    rs786247431,2
    C,F--76630699(+) GTTATA/CTGTTG 1 -- ds50011Minor allele frequency- C:0.12EA 120
    rs1396163401,2
    --76630777(+) GAATAC/TATAAA 1 -- ds50010--------
    rs1155894661,2
    F--76630815(+) AAAGGC/ATCATT 1 -- ds50011Minor allele frequency- A:0.07WA 118
    rs1838092421,2
    --76630893(+) TAGAAC/TATTTG 1 -- ds50010--------
    rs1438349171,2
    C--76630902(+) GAAAG-/AGAT  
            
    AGATA
    1 -- ds50010--------
    rs1880106051,2
    --76630932(+) TAAGCA/CGCACA 1 -- ds50010--------
    rs769577941,2
    C,F--76630941(+) CATAAA/GAAATG 1 -- ds50011Minor allele frequency- G:0.06WA 118
    rs1181707281,2
    C,F--76630996(+) TAAAGT/CTGGTG 1 -- ds50011Minor allele frequency- C:0.02NA 120
    rs801746711,2
    F--76631167(+) TATGTG/TTATCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for IMPG1 (76630832 - 76782395 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IMPG1 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2672500CNV Deletion23128226
    esv1003005CNV Deletion20482838
    esv2674046CNV Deletion23128226
    esv2732316CNV Deletion23290073
    esv1097945CNV Deletion17803354
    esv2658811CNV Deletion23128226
    esv5072CNV Deletion18987735
    esv2732315CNV Deletion23290073
    esv1934970CNV Deletion18987734
    esv2732318CNV Deletion23290073

    Human Gene Mutation Database (HGMD): IMPG1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IMPG1
    DNA2.0 Custom Variant and Variant Library Synthesis for IMPG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602870    OMIM disorders: --

    14 diseases for IMPG1:    
    About MalaCards
    progressive bifocal chorioretinal atrophy    benign concentric annular macular dystrophy    vitelliform macular dystrophy    north carolina macular dystrophy
    retinal drusen    chorioretinitis    macular dystrophy    retinitis
    age related macular degeneration    retinitis pigmentosa    choroiditis    lymphoblastic leukemia
    leukemia    neuronitis

    1 disease from the University of Copenhagen DISEASES database for IMPG1:
    Retinal drusen

    IMPG1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IMPG1
    Human Genome Epidemiology (HuGE) Navigator: IMPG1 (4 documents)

    Export disorders for IMPG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IMPG1 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with IMPG1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan. (PubMed id 10601738)1, 2, 9 Kuehn M.H. and Hageman G.S. (Matrix Biol. 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PubMed id 20201926)1, 4 Joslyn G....White R.L. (Alcohol. Clin. Exp. Res. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis. (PubMed id 9719680)1, 2 Acharya S.... Hollyfield J.G. (Glycobiology 1998)
    7. SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan. (PubMed id 9813076)1, 2 Acharya S.... Hollyfield J.G. (J. Biol. Chem. 1998)
    8. Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies. (PubMed id 9691169)1, 2 Felbor U....Weber B.H.F. (Cytogenet. Cell Genet. 1998)
    9. Molecular genetic analysis of two functional candidate genes in the autosomal recessive retinitis pigmentosa, RP25, locus. (PubMed id 16354621)1, 9 Abd El-Aziz M.M....Bhattacharya S.S. (Curr. Eye Res. 2005)
    10. The benign concentric annular macular dystrophy locus maps to 6p12.3-q16. (PubMed id 14691150)1, 9 van Lith-Verhoeven J.J....Cremers F.P. (amp 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3617 HGNC: 6055 AceView: IMPG1 Ensembl:ENSG00000112706 euGenes: HUgn3617
    ECgene: IMPG1 H-InvDB: IMPG1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for IMPG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IMPG1 gene:
    Search GeneIP for patents involving IMPG1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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