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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ILKAP Gene

protein-coding   GIFtS: 52
GCID: GC02M239079

integrin-linked kinase-associated serine/threonine phosphatase

(Previous name: integrin-linked kinase-associated serine/threonine phosphatase...)
 Explore 2 diseases affiliated with
ILKAP via our new
 Human Malady Compendium 
Biological research products
for ILKAP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Integrin-Linked Kinase-Associated Serine/Threonine Phosphatase1 2     ILKAP22
Integrin-Linked Kinase-Associated Serine/Threonine Phosphatase 2C1 2     ILKAP32
EC 3.1.3.163 8     PP2C-DELTA2
DKFZP434J20311     Integrin-Linked Kinase Associated Phosphatase2
FLJ101811     Protein Phosphatase 2c, Delta Isozyme2

External Ids:    HGNC: 155661   Entrez Gene: 808952   Ensembl: ENSG000001323237   UniProtKB: Q9H0C83   

Export aliases for ILKAP gene to outside databases

Previous GC identifers: GC02M237128 GC02M237760 GC02M239095 GC02M239365 GC02M238861 GC02M238743 GC02M230870


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ILKAP:
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can
interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase
activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of
ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ILKAP_HUMAN, Q9H0C8
Function: Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its
substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates
with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B
signaling axis and may play an important role in inhibiting oncogenic transformation

Gene Wiki entry for ILKAP


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005120.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ILKAP gene promoter:
         STAT1   ATF-2   STAT1beta   Olf-1   c-Jun   Pax-4a   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidILKAP promoter sequence
   Search SABiosciences Chromatin IP Primers for ILKAP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ILKAP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

ILKAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ILKAP gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M239079:  view genomic region     (about GC identifiers)

Start:
239,079,042 bp from pter      End:
239,112,370 bp from pter
Size:
33,329 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ILKAP_HUMAN, Q9H0C8 (See protein sequence)
Recommended Name: Integrin-linked kinase-associated serine/threonine phosphatase 2C  
Size: 392 amino acids; 42907 Da
Cofactor: Binds 2 magnesium or manganese ions per subunit (By similarity)
Subunit: Interacts with ILK. Specific association with ILK is independent of the catalytic activity of either partner
Subcellular location: Cytoplasm
Secondary accessions: B3KM39

Explore the universe of human proteins at neXtProt for ILKAP: NX_Q9H0C8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H0C8

  • 4/5 DME Specific Peptides for ILKAP (Q9H0C8) (see all 5)
     NLGDSRA  VFDGHGG  GDSRAILCR  LKGYVAERKGEREEMQDAHVILNDIT 

    ILKAP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_110395.1  
    ENSEMBL proteins: 
     ENSP00000254654   ENSP00000406254   ENSP00000395301  

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    Uscn Proteins for ILKAP

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0008287protein serine/threonine phosphatase complex ----


    ILKAP for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ILKAP for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001932 PP2C-like
     IPR000222 PP2C_Mn2_Asp60_BS
     IPR015655 Protein_Pase_2C

    Graphical View of Domain Structure for InterPro Entry Q9H0C8

    ProtoNet protein and cluster: Q9H0C8

    1 Blocks protein family: IPB000222 Protein phosphatase 2C subfamily

    UniProtKB/Swiss-Prot: ILKAP_HUMAN, Q9H0C8
    Similarity: Belongs to the PP2C family
    Similarity: Contains 1 PP2C-like domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ILKAP_HUMAN, Q9H0C8
    Function: Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its
    substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates
    with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B
    signaling axis and may play an important role in inhibiting oncogenic transformation
    Catalytic activity: A phosphoprotein + H(2)O = a protein + phosphate
    Enzyme regulation: Inhibited rather than stimulated by magnesium

    Enzyme Number (IUBMB): EC 3.1.3.161 2

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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004722protein serine/threonine phosphatase activity IEA--
    GO:0005515protein binding IPI11331582
    GO:0046872metal ion binding IEA--


    ILKAP for ontologies           About GeneDecksing


    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ilkap):
     behavior/neurological  homeostasis/metabolism 

    ILKAP for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ILKAP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/54 Interacting proteins for ILKAP (Q9H0C81, 3 ENSP000002546544) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ILKQ134181, 3, ENSP000002994214EBI-2620298,EBI-747644 I2D: score=3 STRING: ENSP00000299421
    HGSO149643, ENSP000003312014I2D: score=1 STRING: ENSP00000331201
    ACVR1Q047713I2D: score=1 
    AXIN2Q9Y2T13I2D: score=1 
    BMPR1BO002383I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470protein dephosphorylation IEA--
    GO:0007090regulation of S phase of mitotic cell cycle IEA--
    GO:0045786negative regulation of cell cycle IEA--


    ILKAP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ILKAP

    2 HMDB Compounds for ILKAP    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--
    Manganesemanganese 7439-96-5--
    Search CenterWatch for drugs/clinical trials and news about ILKAP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ILKAP gene (2 alternative transcripts): 
    NM_030768.2  NM_176799.1  

    Unigene Cluster for ILKAP:

    Integrin-linked kinase-associated serine/threonine phosphatase
    Hs.92033  [show with all ESTs]
    Unigene Representative Sequence: BC050422
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254654(uc002vxv.3 uc010zns.2 uc021vyt.1 uc021vyu.1 uc010znt.1)
    ENST00000465131 ENST00000463129(uc002vxw.3) ENST00000450411 ENST00000466468
    ENST00000479400 ENST00000457149 ENST00000498727 ENST00000467133 ENST00000490837


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    Additional cDNA sequence: 

    AK001043.1 AL136850.1 AY024365.1 BC006576.2 BC035746.1 BC050422.1 CR533533.1 FJ491380.1 
    FJ491381.1 HQ658059.1 HQ658060.1 

    14 DOTS entries:

    DT.313119  DT.97763058  DT.95082880  DT.313120  DT.40193121  DT.99968644  DT.120976684  DT.95082870 
    DT.40214385  DT.95217854  DT.100719339  DT.86995031  DT.97842908  DT.91653760 

    24/175 AceView cDNA sequences (see all 175):

    CR533533 CR618491 AA595667 BP346595 Z41850 AI217079 BU737452 CK902339 
    NM_176799 BM695546 BQ684678 AL526998 AA809125 BU191859 NM_030768 AL136850 
    BU553541 AI969275 AA237008 BX951135 BM550302 AA767177 F11116 BQ026402 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ILKAP (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b
    SP1:              -     -                       -     -     -                                         -                 -               
    SP2:                                      -     -     -     -                                         -                 -               
    SP3:                                                                                                  -                                 
    SP4:              -     -                                                                                                               
    SP5:                    -                                                                                                               


    ECgene alternative splicing isoforms for ILKAP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ILKAP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTGTAAATA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ILKAP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ILKAP

    SOURCE GeneReport for Unigene cluster: Hs.92033

    UniProtKB/Swiss-Prot: ILKAP_HUMAN, Q9H0C8
    Tissue specificity: Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various
    smooth muscle tissues

        SABiosciences Expression via Pathway-Focused PCR Array including ILKAP: 
              Protein Phosphatases in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ILKAP gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ILKAP1 integrin-linked kinase-associated serine/threonine more 77.86(n)
    85.53(a)
      424850  XM_422661.3  XP_422661.2 
    lizard
    (Anolis carolinensis)
    Reptilia ILKAP6
    --
    80(a)
    1 ↔ 1
    3(35341288-35357718)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1629851 zgc:162985 63.86(n)
    64.56(a)
      100037350  NM_001089504.2  NP_001082973.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F33A8.61 Protein F33A8.6 50.57(n)
    41.03(a)
      185220  NM_063969.1  NP_496370.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G180301 putative protein phosphatase 2C 8 50.23(n)
    40.07(a)
      838383  NM_101665.2  NP_564045.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g03144001 hypothetical protein 49.45(n)
    40.96(a)
      4346692  NM_001069375.1  NP_001062840.1 


    ENSEMBL Gene Tree for ILKAP (if available)
    TreeFam Gene Tree for ILKAP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ILKAP gene
    PPM1F2  PPM1L2  PPM1K2  PPM1E2  
    3 SIMAP similar genes for ILKAP using alignment to 5 protein entries:     ILKAP_HUMAN (see all proteins):
    ILKAP2    ILKAP3    PPM1F

    ILKAP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/713 NCBI SNPs in ILKAP are shown (see all 713    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1431169161,2
    --239078656(+) TCTGAC/TGCATG 1 -- ds50010--------
    rs1512031431,2
    --239078797(+) CTTGAC/TTAACC 1 -- ds50010--------
    rs1403862151,2
    --239078852(+) CCAGGA/GTCATC 1 -- ds50010--------
    rs1503878111,2
    --239078885(+) ATGCCC/TGTGAA 1 -- ds50010--------
    rs1853457071,2
    --239078915(+) CAGCAA/GCCTGC 1 -- ds50010--------
    rs1379071051,2
    --239078916(+) AGCAGC/GCTGCA 1 -- ds50010--------
    rs1894061281,2
    --239078947(+) AGATGA/CCTATA 1 -- ds50010--------
    rs1457756561,2
    --239078971(+) GGAAAG/TACAGC 1 -- ds50010--------
    rs1387032721,2
    --239079017(+) GAGGTA/GCTCAC 1 -- ds50010--------
    rs1812097951,2
    --239079022(+) GCTCAC/GAGTAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for ILKAP (239079042 - 239112370 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ILKAP
         1 CNV: 30110

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ILKAP for disorders           About GeneDecksing

    2 diseases for ILKAP:    About MalaCards
    oral cancer    malaria


    Export disorders for ILKAP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ILKAP gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with ILKAP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ILKAP regulates ILK signaling and inhibits anchorage-independent growth. (PubMed id 14990992)1, 2, 9 Kumar A.S....Hannigan G.E. (2004)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    7. Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1. (PubMed id 11331582)1, 2 Leung-Hagesteijn C.... Hannigan G.E. (2001)
    8. Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1 Demirkan A....Schmitz G. (2012)
    9. Palladin is a novel binding partner of ILKAP in eukar yotic cells. (PubMed id 21782789)1 Zhou W....Zhang Y. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80895 HGNC: 15566 AceView: ILKAP Ensembl:ENSG00000132323 euGenes: HUgn80895
    ECgene: ILKAP H-InvDB: ILKAP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ILKAP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ILKAP gene:
    Search GeneIP for patents involving ILKAP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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