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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

IL8 Gene

protein-coding   GIFtS: 68
GCID: GC04P074595

Interleukin 8

Microbiology & Infectious Diseases Congress
  See related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Interleukin 81 2     T-Cell Chemotactic Factor2 3
Granulocyte Chemotactic Protein 11 2 3     GCP12
Monocyte-Derived Neutrophil Chemotactic Factor1 2 3     LECT2
Monocyte-Derived Neutrophil-Activating Peptide1 2 3     LUCT2
Alveolar Macrophage Chemotactic Factor I1 2     LYNAP2
Beta Endothelial Cell-Derived Neutrophil Activating Peptide1 2     NAF2
Chemokine (C-X-C Motif) Ligand 81 2     NAP12
Lung Giant Cell Carcinoma-Derived Chemotactic Protein1 2     Beta-Thromboglobulin-Like Protein2
Lymphocyte Derived Neutrophil Activating Peptide1 2     emoctakin2
Neutrophil-Activating Peptide 11 2     interleukin-82
Tumor Necrosis Factor-Induced Gene 11 2     Small Inducible Cytokine Subfamily B, Member 82
CXCL82 3     Emoctakin3
GCP-12 3     IL-83
MDNCF2 3     C-X-C Motif Chemokine 83
MONAP2 3     Neutrophil-Activating Protein 13
NAP-12 3     Protein 3-10C3

External Ids:    HGNC: 60251   Entrez Gene: 35762   Ensembl: ENSG000001694297   OMIM: 1469305   UniProtKB: P101453   

Export aliases for IL8 gene to outside databases

Previous GC identifers: GC04P074845 GC04P075006 GC04P075072 GC04P074971 GC04P070417

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL8 Gene:
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major
mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a
chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis
of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members
of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. (provided by
RefSeq, Jul 2008)

GeneCards Summary for IL8 Gene: 
IL8 (interleukin 8) is a protein-coding gene. Diseases associated with IL8 include bronchiolitis, and lung giant cell carcinoma, and among its related super-pathways are MIF Mediated Glucocorticoid Regulation and Toll-like receptor signaling pathway. GO annotations related to this gene include interleukin-8 receptor binding and chemokine activity. An important paralog of this gene is PPBP.

UniProtKB/Swiss-Prot: IL8_HUMAN, P10145
Function: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is
also involved in neutrophil activation. It is released from several cell types in response to an inflammatory
stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity
on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to
IL-8(1-77), respectively

Gene Wiki entry for IL8 (Interleukin 8) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_022778.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IL8 gene promoter:
         GR   AML1a   HNF-4alpha2   NF-E2 p45   HNF-4alpha1   C/EBPalpha   GR-alpha   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL8 promoter sequence
   Search SABiosciences Chromatin IP Primers for IL8

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13-q21   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13-q21

IL8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL8 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P074595:  view genomic region     (about GC identifiers)

74,606,223 bp from pter      End:
74,609,433 bp from pter
3,211 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IL8_HUMAN, P10145 (See protein sequence)
Recommended Name: Interleukin-8 precursor  
Size: 99 amino acids; 11098 Da
Subunit: Homodimer
Subcellular location: Secreted
6/10 PDB 3D structures from and Proteopedia for IL8 (see all 10):
1ICW (3D)        1IKL (3D)        1IKM (3D)        1IL8 (3D)        1ILP (3D)        1ILQ (3D)    
Secondary accessions: B2R4L8 Q6FGF6 Q6LAE6 Q96RG6 Q9C077 Q9UCE1 Q9UCR8 Q9UCR9 Q9UCS0
Alternative splicing: 2 isoforms:  P10145-1   P10145-2   

Explore the universe of human proteins at neXtProt for IL8: NX_P10145

Explore proteomics data for IL8 at MOPED 

Post-translational modifications:

  • UniProtKB: Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral
    blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8.
    IL-8(6-77) is the most promiment form
  • UniProtKB: Citrullination at Arg-27 prevents proteolysis, and dampens tissue inflammation, it also enhances leukocytosis,
    possibly through impaired chemokine clearance from the blood circulation
  • View neXtProt modification sites for NX_P10145

  • IL8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IL8 Protein Expression
    REFSEQ proteins: NP_000575.1  
    ENSEMBL proteins: 
     ENSP00000306512   ENSP00000385908  
    Reactome Protein details: P10145
    Human Recombinant Protein Products for IL8: 
    EMD Millipore Purified and/or Recombinant IL8 Protein
    R&D Systems Recombinant & Natural Proteins for IL8 (CXCL8/IL-8)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for IL8
    OriGene Protein Over-expression Lysate for IL8
    OriGene MassSpec for IL8 
    OriGene Custom Protein Services for IL8
    GenScript Purified and Recombinant Proteins for IL8
    Novus Biologicals IL8 Proteins
    Novus Biologicals IL8 Lysates
    Sino Biological Recombinant Protein for IL8
    Sino Biological Cell Lysate for IL8 
    ProSpec Recombinant Protein for IL8
    Cloud-Clone Corp. Proteins for IL8 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--

    IL8 for ontologies           About GeneDecksing

    IL8 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of IL8
    R&D Systems Antibodies for IL8 (CXCL8/IL-8)
    OriGene Antibodies for IL8
    OriGene Custom Antibody Services for IL8
    GenScript Superior Antibodies for IL8
    Novus Biologicals IL8 Antibodies
    Abcam antibodies for IL8
    Cloud-Clone Corp. Antibodies for IL8 
    ThermoFisher Antibody for IL8
    LSBio Antibodies in human, mouse, rat for IL8 

    Assay Products for IL8: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for IL8
    R&D Systems Flow Cytometry Kits for IL8 (CXCL8/IL-8)         (see all)
    GenScript Custom Assay Services for IL8
    Enzo Life Sciences assays for IL8
    Cloud-Clone Corp. ELISAs for IL8 
    Cloud-Clone Corp. CLIAs for IL8

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ENDOLIG: Endogenous ligands
    IL: Interleukins and interleukin receptors

    4 InterPro protein domains:
     IPR027206 IL8
     IPR001811 Chemokine_IL8-like_dom
     IPR001089 Chemokine_CXC
     IPR018048 Chemokine_CXC_CS

    Graphical View of Domain Structure for InterPro Entry P10145

    ProtoNet protein and cluster: P10145

    1 Blocks protein domain: IPB002473 Interleukin-8 signature

    UniProtKB/Swiss-Prot: IL8_HUMAN, P10145
    Similarity: Belongs to the intercrine alpha (chemokine CxC) family

    IL8 for domains           About GeneDecksing

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IL8_HUMAN, P10145
    Function: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is
    also involved in neutrophil activation. It is released from several cell types in response to an inflammatory
    stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity
    on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to
    IL-8(1-77), respectively
    Induction: By ER stress in a DDIT3/CHOP-dependent manner

         Genatlas biochemistry entry for IL8:
    interleukin 8 (see IMC2@),neutrophil activating peptide 1,monocyte-derived neutrophil chemotactic factor,with a
    direct growth potentiating activity in malignant mesothelioma

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005153interleukin-8 receptor binding IPI1840701
    GO:0005515protein binding IPI10880251
    GO:0008009chemokine activity IEA--
    IL8 for ontologies           About GeneDecksing

         2 GenomeRNAi human phenotypes for IL8:
     Increased cell death in breast  Synthetic lethal with Ras 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Il8):
     hematopoietic system  immune system 

    IL8 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cxcl15tm1Lira for IL8

       inGenious Targeting Laboratory - Custom generated mouse model solutions for IL8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IL8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IL8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IL8 

    miRTarBase miRNAs that target IL8:
    hsa-mir-146a (MIRT004409), hsa-mir-204 (MIRT005832)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL8
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate IL8 (see all 33):
    hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-106a hsa-miR-372 hsa-miR-93 hsa-miR-889 hsa-miR-302b
    SwitchGear 3'UTR luciferase reporter plasmidIL8 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IL8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL8

    Gene Editing
    DNA2.0 Custom Protein Engineering Service for IL8
    Sirion Biotech Customized adenovirus for overexpression of IL8

    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for IL8 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IL8 (NM_000584)
    Sino Biological Human cDNA Clone for IL8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IL8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL8
    Sirion Biotech Customized lentivirus for stable overexpression of IL8 
                         Customized lentivirus expression plasmids for stable overexpression of IL8 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for IL8
    Search LifeMap BioReagents cell lines for IL8
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL8

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for IL8 About   (see all 57)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1PEDF Induced Signaling
    MIF Mediated Glucocorticoid Regulation0.94
    NFAT Signaling and Lymphocyte Interactions0.57
    MIF Regulation of Innate Immune Cells0.94
    PGC1Alpha Pathway0.51
    PEDF Induced Signaling0.73
    STAT3 Pathway0.47
    all-trans-Retinoic Acid Signaling in Brain0.71
    Endothelin-1 Signaling Pathway0.46
    2Toll-like receptor signaling pathway
    Toll-like receptor signaling pathway0.93
    Chagas disease (American trypanosomiasis)0.33
    Toll-like receptor signaling pathway0.93
    Hepatitis B0.31
    3Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response
    Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response0.94
    Immune response TLR signaling pathways0.94
    4Chemokine Signaling
    Chemokine Signaling0.33
    Chemokine signaling pathway0.33
    5TGF-Beta Pathway
    TGF-Beta Pathway0.60
    Regulation of eIF4 and p70S6K0.43
    MAPK Family Pathway0.60
    SOCS Pathway0.40
    JAK-STAT Pathway0.57

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/8 EMD Millipore Pathways for IL8 (see all 8)
        Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response
    Immune response Role of integrins in NK cells cytotoxicity
    Selected targets of GCR-alpha
    Immune response MIF-mediated glucocorticoid regulation
    Immune response MIF in innate immunity response

    2 R&D Systems Pathways for IL8
        NOD-like Receptor Signaling Pathways
    Toll-Like receptor Signaling Pathways

    5/27 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IL8 (see all 27)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    NFAT Signaling and Lymphocyte Interactions
    Tec Kinases Signaling

    5/14 GeneGo (Thomson Reuters) Pathways for IL8 (see all 14)
        Immune response MIF-mediated glucocorticoid regulation
    Immune response Bacterial infections in normal airways
    Immune response MIF in innate immunity response
    Immune response TLR signaling pathways
    Apoptosis and survival Lymphotoxin-beta receptor signaling

    5/14 BioSystems Pathways for IL8 (see all 14)
        EBV LMP1 signaling
    Senescence and Autophagy
    SIDS Susceptibility Pathways
    Spinal Cord Injury
    Toll-like receptor signaling pathway

    5/12        Reactome Pathways for IL8 (see all 12)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Signaling by GPCR
    GPCR ligand binding
    Class A/1 (Rhodopsin-like receptors)

    5/22         Kegg Pathways  (Kegg details for IL8) (see all 22):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway
    NF-kappa B signaling pathway
    Toll-like receptor signaling pathway
    NOD-like receptor signaling pathway

    IL8 for pathways           About GeneDecksing


        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/93 Interacting proteins for IL8 (P101453 ENSP000003065124) via UniProtKB, MINT, STRING, and/or I2D (see all 93)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PF4P027763, ENSP000002960294I2D: score=3 STRING: ENSP00000296029
    MTDHQ86UE43, ENSP000003382354I2D: score=1 STRING: ENSP00000338235
    RPS3P233963, ENSP000002785724I2D: score=1 STRING: ENSP00000278572
    CXCR2P250253, ENSP000003196354I2D: score=4 STRING: ENSP00000319635
    RELAQ042063, ENSP000003842734I2D: score=1 STRING: ENSP00000384273
    About this table

    Gene Ontology (GO): 5/28 biological process terms (GO ID links to tree view) (see all 28):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis TAS11483765
    GO:0002237response to molecule of bacterial origin IDA19912257
    GO:0006928cellular component movement TAS10820279
    GO:0006954inflammatory response TAS11483765
    GO:0006955immune response IEA--

    IL8 for ontologies           About GeneDecksing

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    IL8 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IL8

    2 HMDB Compounds for IL8    About this table
    CompoundSynonyms CAS #PubMed Ids
    Salbutamol(l)-albuterol (see all 97)18559-94-9--
    Simvastatin(+)-Simvastatin (see all 28)79902-63-9--

    10/138 Novoseek inferred chemical compound relationships for IL8 gene (see all 138)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rantes 92.7 1369 9723955 (8), 17207890 (7), 10619832 (7), 16413378 (6) (see all 99)
    groalpha 86.1 191 11495082 (7), 9641651 (7), 17922696 (5), 9889409 (4) (see all 81)
    fmlp 79.7 471 7837814 (9), 16249234 (7), 15494208 (5), 9013980 (5) (see all 99)
    leukotriene b4 78.5 560 8003341 (9), 8973284 (5), 9482389 (5), 12149532 (5) (see all 99)
    vegf 76.4 1297 11234901 (9), 10334214 (9), 17349553 (8), 9457313 (8) (see all 99)
    endotoxin 74.4 268 2007851 (5), 11451261 (5), 18485432 (4), 16384605 (4) (see all 99)
    grogamma 72.8 23 8702798 (3), 15832427 (2), 9553055 (2), 10695618 (1) (see all 11)
    grobeta 68 26 10600366 (3), 8702798 (3), 15832427 (2), 9553055 (2) (see all 12)
    il 10 67.4 70 18363812 (4), 9543183 (2), 19723087 (2), 20041183 (2) (see all 56)
    lipoteichoic acid 67.3 89 10570304 (7), 16619004 (4), 8262617 (4), 19250704 (3) (see all 37)

    Search CenterWatch for drugs/clinical trials and news about IL8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IL8 gene: 

    Unigene Cluster for IL8:

    Interleukin 8
    Hs.624  [show with all ESTs]
    Unigene Representative Sequence: NM_000584
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307407(uc003hhe.3) ENST00000401931 ENST00000483500
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL8
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate IL8 (see all 33):
    hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-106a hsa-miR-372 hsa-miR-93 hsa-miR-889 hsa-miR-302b
    SwitchGear 3'UTR luciferase reporter plasmidIL8 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IL8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL8
    OriGene clones in human, mouse for IL8 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IL8 (NM_000584)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IL8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL8
    Sirion Biotech Customized lentivirus for stable overexpression of IL8 
                         Customized lentivirus expression plasmids for stable overexpression of IL8 
    OriGene qPCR primer pairs and template standards for IL8
    OriGene qSTAR qPCR primer pairs in human, mouse for IL8
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IL8
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL8

    Additional mRNA sequence: 

    AK131067.1 AK311874.1 BC013615.1 BT007067.1 CR542151.1 M17017.1 M26383.1 Y00787.1 

    24/25 DOTS entries (see all 25):

    DT.92451091  DT.452985  DT.97822713  DT.121222191  DT.100764374  DT.121222188  DT.100890247  DT.121222199 
    DT.121222180  DT.100722366  DT.100890252  DT.121222165  DT.100890251  DT.100890257  DT.92451100  DT.92451101 
    DT.95366903  DT.100691364  DT.100842594  DT.100890241  DT.100890254  DT.121222196  DT.92451080  DT.92451094 

    24/756 AceView cDNA sequences (see all 756):

    BU169639 AA381356 AA381625 CR600500 CR601902 AA381931 AA381999 BM888479 
    AA362132 AA381576 BQ215118 BI962588 AA381795 BM907296 NM_000584 AA381228 
    CD367465 AA381459 BQ051231 AW780211 CB306060 AA362358 AA381891 AA362139 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for IL8    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b
    SP2:                    -                           

    ECgene alternative splicing isoforms for IL8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IL8 expression in normal human tissues (normalized intensities)      IL8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    IL8 Expression
    About this image

    IL8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/25 selected tissues (see all 25) fully expand
     Endothelium (Cardiovascular System)    fully expand to see all 6 entries
             Human corneal endothelial cells
             Endothelial-like cells ( Derivation and purification of endothelial precursor cells...
             Human Bladder Microvascular Endothelial Cells (HBdMEC)   
     Bone (Muscoskeletal System)    fully expand to see all 5 entries
             Bone Marrow
             Bone marrow-derived mesenchymal stem cells
             BONE MARROW   
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 5 entries
             Wharton's jelly-derived stem cells
             Human Umbillical Artery Smooth Muscle Cells (HUASMC)   
     Mesenchymal Stem Cells
             Decidua-derived mesenchymal stem cells
             Human Umbilical Mesenchymal Stem Cells (HUMSC)   
     Lung (Respiratory System)    fully expand to see all 3 entries
             Human Pulmonary Artery Smooth Muscle Cells (HPASMC)   

    See IL8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IL8

    SOURCE GeneReport for Unigene cluster: Hs.624
        SABiosciences Expression via Pathway-Focused PCR Arrays including IL8 (see all 24): 
              HIV Host Response in human mouse rat
              Antiviral Response in human mouse rat
              Nitric Oxide Signaling Pathway in human mouse rat
              T-cell & B-cell Activation in human mouse rat
              Stress & Toxicity PathwayFinder in human mouse rat

    OriGene qPCR primer pairs and template standards for IL8
    OriGene qSTAR qPCR primer pairs in human, mouse for IL8
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IL8
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL8
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL8
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IL8 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Il85 chemokine (C-X-C motif) ligand 15   --   5 (44.78 cM) 90794534 
    (Gallus gallus)
    Aves IL81 interleukin 8 60.76(n)
      396495  NM_205498.1  NP_990829.1 
    (Anolis carolinensis)
    Reptilia IL86
    1 ↔ 1
    possible ortholog

    ENSEMBL Gene Tree for IL8 (if available)
    TreeFam Gene Tree for IL8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68)
    About This Section
    Paralogs for IL8 gene
    PPBP2  PF42  CXCL12  PF4V12  CXCL62  CXCL32  CXCL52  CXCL22  
    18/25 SIMAP similar genes for IL8 using alignment to 2 protein entries:     IL8_HUMAN (see all proteins) (see all similar genes):
    CXCL6    CXCL5    PPBP    PF4    CXCL1    CXCL2
    CXCL12    CXCL3    PF4V1    CCL8    CCL3L1    CCL3L3
    CCL11    CCL18    CCL5    CXCL13    CXCL10    CCL2

    IL8 for paralogs           About GeneDecksing

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/235 SNPs in IL8 are shown (see all 235)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 4 posSequence#AA
    C--70419362(-) ATTCCC/TTTTTT 1 -- int10--------
    --74482423(+) AGCAAA/CGAAAC 1 -- us2k10--------
    C--74482435(+) TGGAGA/TTTTCT 1 -- us2k10--------
    --74482438(+) AGTTTC/TCTTTA 1 -- us2k10--------
    --74482464(+) TTACCA/TATCCG 1 -- us2k10--------
    C--74482562(+) ATTTCA/GTTGTC 1 -- us2k10--------
    F--74482648(+) TTTGAT/AGTTGT 1 -- us2k12Minor allele frequency- A:0.02NS 86
    --74482749(+) TCATCA/GCTGTA 1 -- us2k10--------
    C--74482754(+) ACTGTA/GTTTTA 1 -- us2k10--------
    --74482816(+) TAAGTC/GAGGTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for IL8 (74606223 - 74609433 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for IL8: --

    Human Gene Mutation Database (HGMD): IL8
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing IL8
    DNA2.0 Custom Variant and Variant Library Synthesis for IL8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 146930    OMIM disorders: --

    20/415 diseases for IL8 (see all 415):    About MalaCards
    bronchiolitis    lung giant cell carcinoma    mycobacterium marinum    adult respiratory distress syndrome
    cryptogenic organizing pneumonia    stenotrophomonas maltophilia    spermatocele    sepsis in premature infants
    alcoholic hepatitis    mycobacterium fortuitum    bagassosis    neutrophil-specific granule deficiency
    meningitis    chorioamnionitis    common cold    felty's syndrome
    common wart    pneumonia    funisitis    opisthorchiasis

    13 diseases from the University of Copenhagen DISEASES database for IL8:
    Lung disease     Cancer     Gastritis     Cystic fibrosis
    Vascular disease     Periodontitis     Chorioamnionitis     Inflammatory bowel disease
    Arthritis     Mastitis     Psoriasis     Endometriosis
    Peptic ulcer

    IL8 for disorders           About GeneDecksing

    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/98 Novoseek inferred disease relationships for IL8 gene (see all 98)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 91.7 3968 9462219 (9), 8601968 (6), 10740342 (5), 1702929 (4) (see all 99)
    inflammation 90.2 1154 12697917 (4), 10680520 (4), 15104334 (4), 15901266 (4) (see all 99)
    tumors 81.8 3953 11181444 (8), 8601968 (6), 12471616 (6), 16088182 (5) (see all 99)
    bronchoalveolar lavage fluid 72.9 158 7712280 (4), 10933164 (3), 16077402 (3), 15909061 (3) (see all 99)
    systemic inflammatory response syndrome 70.3 31 8143477 (2), 9558403 (2), 9038289 (2), 16227031 (2) (see all 21)
    pulmonary disease chronic obstructive 68 39 8563494 (2), 12915744 (2), 11108181 (2), 16181530 (2) (see all 27)
    sepsis 66.2 233 1612748 (6), 17368039 (5), 15730597 (5), 9120108 (4) (see all 99)
    cystic fibrosis 65.2 102 7940424 (6), 7639556 (3), 8476069 (3), 17880760 (2) (see all 65)
    rheumatoid arthritis 64.5 130 1932367 (2), 8961381 (2), 14750259 (2), 10437780 (2) (see all 94)
    airways disease 63.8 23 7927669 (2), 10417151 (1), 10460760 (1), 9199432 (1) (see all 14)

    Genetic Association Database (GAD): IL8
    Human Genome Epidemiology (HuGE) Navigator: IL8 (282 documents)

    Export disorders for IL8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IL8 gene, integrated from 9 sources (see all 7195) (see top 10):
    (articles sorted by number of sources associating them with IL8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The neutrophil-activating proteins interleukin 8 and beta- thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms. (PubMed id 2145175)1, 2, 9 van Damme J.... Billiau A. (1990)
    2. Polymorphisms of the IL-8 and CXCR2 genes are not associated with Behcet's disease. (PubMed id 15630732)1, 4, 9 Duymaz-Tozkir J....Gul A. (2005)
    3. Lack of association of interleukin-6 and interleukin-8 gene polymorphisms in Chinese patients with systemic lupus erythematosus. (PubMed id 17115422)1, 4, 9 Huang C.M....Tsai F.J. (2006)
    4. Polymorphisms in interleukin 8 and its receptors (IL8, IL8RA and IL8RB) and association of common IL8 receptor variants with peripheral blood eosinophil counts. (PubMed id 16897191)1, 4, 9 Cheong H.S....Park C.S. (2006)
    5. Genetic variation in the interleukin-8 gene promoter and vaginal concentrations of interleukin-8 are not associated with bacterial vaginosis during pregnancy. (PubMed id 16038986)1, 4, 9 Diaz-Cueto L....Arechavaleta-Velasco F. (2005)
    6. Relation of tumor necrosis factor (TNF) gene polymorphisms with serum concentrations and in vitro production of TNF-alpha and interleukin-8 in heavy drinkers. (PubMed id 15902922)1, 4, 9 Gonzalez-Quintela A....Perez L.F. (2004)
    7. The Effects of Genetic Polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced Gastroduodenal Diseases in Korea. (PubMed id 19077731)1, 4, 9 Kang J.M....Song I.S. (2008)
    8. Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus. (PubMed id 16719905)1, 4, 9 Sanchez E....Koeleman B.P. (2006)
    9. Association of interleukin-8 with cachexia from patie nts with low-third gastric cancer. (PubMed id 20037740)1, 4, 9 Song B....Wang X. (2009)
    10. T-251A polymorphism of IL-8 relating to the development of histological gastritis and G-308A polymorphism of TNF-alpha relating to the development of macroscopic erosion. (PubMed id 18301299)1, 4, 9 Szoke D....Tulassay Z. (2008)
    11. Genetic polymorphisms of interleukin-1B (IL-1B), IL-6, IL-8, and IL-10 and risk of prostate cancer. (PubMed id 16618781)1, 4, 9 Michaud D.S....Hayes R.B. (2006)
    12. Association study suggests opposite effects of polymorphisms within IL8 on bronchial asthma and respiratory syncytial virus bronchiolitis. (PubMed id 15356575)1, 4, 9 Heinzmann A....Deichmann K.A. (2004)
    13. Influence of IL1B polymorphism on CpG island hypermet hylation in Helicobacter pylori-infected gastric cancer. (PubMed id 20405297)1, 4, 9 Yoo E.J....Kang G.H. (2010)
    14. Interleukin (IL)-1beta, IL-1 receptor antagonist, IL- 6, IL-8, IL-10, and tumor necrosis factor alpha gene polymorphisms in patients with febrile seizures. (PubMed id 20486195)1, 4, 9 Chou I.C....Tsai F.J. (2010)
    15. Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytok ine genes. (PubMed id 19692203)1, 4, 9 Reyes-Gibby C.C....Spitz M.R. (2009)
    16. Genetic polymorphisms of interleukin 8 and risk of ulcerative colitis in the Chinese population. (PubMed id 19348790)1, 4, 9 Li K....Mao D. (2009)
    17. Cytokine (IL-6) and chemokine (IL-8) gene polymorphisms among rheumatoid arthritis patients in Taiwan. (PubMed id 18799095)1, 4, 9 Lo S.F....Tsai F.J. (2008)
    18. Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis. (PubMed id 17309748)1, 4, 9 Hofner P....Mandi Y. (2007)
    19. Cytokine gene polymorphisms in bullous pemphigoid in a Chinese population. (PubMed id 16403098)1, 4, 9 Chang Y.T....Tsai S.F. (2006)
    20. IL-8 (-251 A/T) and CXCR2 (+1208 C/T) gene polymorphisms and risk of multiple sclerosis in Iranian patients. (PubMed id 16793206)1, 4, 9 Kamali-Sarvestani E....Vessal M. (2006)
    21. Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer. (PubMed id 16937502)1, 4, 9 Theodoropoulos G....Gazouli M. (2006)
    22. Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease. (PubMed id 16429233)1, 4, 9 Matheson M.C....Abramson M.J. (2006)
    23. Polymorphism in the IL-8 gene, but not in the TLR4 gene, increases the severity of acute pancreatitis. (PubMed id 17124436)1, 4, 9 Hofner P....Mandi Y. (2006)
    24. Genetic association analysis of the IGFBP7, ADAMTS3, and IL8 genes as the potential osteoarthritis susceptibility that maps to chromosome 4q. (PubMed id 15708897)1, 4, 9 Kawahara C....Loughlin J. (2005)
    25. Influence of cytokine and ICAM-1 gene polymorphisms on susceptibility to chronic pancreatitis. (PubMed id 15917409)1, 4, 9 Howell W.M....Bateman A.C. (2005)
    26. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. (PubMed id 16284368)1, 4, 9 Taguchi A....Goto H. (2005)
    27. Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma. (PubMed id 15598788)1, 4, 9 Savage S.A....Chanock S.J. (2004)
    28. Interleukin 8 gene polymorphism is associated with increased risk of nephritis in cutaneous vasculitis. (PubMed id 12415593)1, 4, 9 Amoli M.M....Gonzalez-Gay M.A. (2002)
    29. Association of interleukin-8 gene polymorphism with c achexia from patients with gastric cancer. (PubMed id 19929572)1, 4, 9 Bo S....Xiaobo L. (2010)
    30. Association of common polymorphisms in IL10, and in o ther genes related to inflammatory response and obesity with colorectal cancer. (PubMed id 19760027)1, 4, 9 Tsilidis K.K....Platz E.A. (2009)
    31. Common polymorphisms in interleukin genes (IL4, IL6, IL8 and IL12) are not associated with alcoholic liver disease or alcoholism in Spanish men. (PubMed id 19185507)1, 4, 9 Marcos M....Laso F.J. (2009)
    32. Interleukin 8 gene polymorphisms and susceptibility to restenosis after percutaneous coronary intervention. (PubMed id 19404719)1, 4, 9 Vogiatzi K....Spandidos D.A. (2009)
    33. Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion. (PubMed id 19347053)1, 4, 9 Steinbrugger I....Weger M. (2009)
    34. Asthma and genes encoding components of the vitamin D pathway. (PubMed id 19852851)1, 4, 9 BossAc Y....Laprise C. (2009)
    35. Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. (PubMed id 19267370)1, 4, 9 Wang M.H....Platz E.A. (2009)
    36. Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. (PubMed id 18676870)1, 4, 9 Hsing A.W....Chanock S.J. (2008)
    37. Interleukin promoter polymorphisms and prognosis in colorectal cancer. (PubMed id 18448485)1, 4, 9 Wilkening S....Forsti A. (2008)
    38. Modulation of cystic fibrosis lung disease by variants in interleukin-8. (PubMed id 18563170)1, 4, 9 Hillian A.D....Drumm M.L. (2008)
    39. Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis. (PubMed id 19009622)1, 4, 9 Corvol H....Clement A. (2008)
    40. A single nucleotide polymorphism in the matrix metalloproteinase-1 and interleukin-8 gene promoter predicts poor prognosis in tongue cancer. (PubMed id 18276095)1, 4, 9 Shimizu Y....Yoshizaki T. (2008)
    41. Interleukin (IL)-12 receptor beta1 codon 378 G homozygote and allele, but not IL-1 (beta-511 promoter, 3953 exon 5, receptor antagonist), IL-2 114, IL-4-590 intron 3, IL-8 3'-UTR 2767, and IL-18 105, are associated with higher susceptibility to leiomyoma. (PubMed id 17222831)1, 4, 9 Hsieh Y.Y....Tsai F.J. (2007)
    42. Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes. (PubMed id 17444864)1, 4, 9 Seno H....Chiba T. (2007)
    43. Cytokine genotype and phenotype effects on lung function decline in firefighters. (PubMed id 17351514)1, 4, 9 Josyula A.B....Burgess J.L. (2007)
    44. Association between human African trypanosomiasis and the IL6 gene in a Congolese population. (PubMed id 16720107)1, 4, 9 Courtin D....Garcia A. (2007)
    45. [Association of cytokines genes (ILL, IL1RN, TNF, LTA, IL6, IL8, IL0) polymorphic markers with chronic obstructive pulmonary disease] (PubMed id 17380888)1, 4, 9 Danilko K.V....Victorova T.V. (2007)
    46. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. (PubMed id 17908769)1, 4, 9 Emonts M....Sanders E.A. (2007)
    47. Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma. (PubMed id 17498967)1, 4, 9 Hildebrand F....Pape H.C. (2007)
    48. Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population. (PubMed id 17355643)1, 4, 9 Huang H.Y....Helzlsouer K.J. (2007)
    49. Association of IL-8 (-251)T/A polymorphism with susceptibility to and aggressiveness of nasopharyngeal carcinoma. (PubMed id 17869651)1, 4, 9 Ben Nasr H....Chouchane L. (2007)
    50. Genetic variation in IL-8 associated with increased risk and poor prognosis of breast carcinoma. (PubMed id 16698420)1, 4, 9 Snoussi K....Chouchane L. (2006)
    51. Inflammation-related gene polymorphisms and colorectal adenoma. (PubMed id 16775170)1, 4, 9 Gunter M.J....Rothman N. (2006)
    52. Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections. (PubMed id 16503988)1, 4, 9 Puthothu B....Heinzmann A. (2006)
    53. The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. (PubMed id 15710978)1, 4, 9 Ohyauchi M....Shimosegawa T. (2005)
    54. Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia. (PubMed id 16107886)1, 4, 9 Lehrnbecher T....Schwabe D. (2005)
    55. Genetic polymorphism of interleukin-8 (IL-8) is associated with Helicobacter pylori-induced duodenal ulcer. (PubMed id 15627645)1, 4, 9 Gyulai Z....Mandi Y. (2004)
    56. [Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis] (PubMed id 15220553)1, 4, 9 Kim M.S....Lee M.S. (2004)
    57. Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO- alpha and leaves RANTES and MCP-2 intact. (PubMed id 11023497)1, 2, 9 Van den Steen P.E.... Opdenakker G. (2000)
    58. Structure and activity of a chimeric interleukin-8-melanoma-growth- stimulatory-activity protein. (PubMed id 8631339)1, 2, 9 Sticht H.... Rosch P. (1996)
    59. Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. (PubMed id 2007144)1, 2, 9 Clark-Lewis I....Aebersold R. (1991)
    60. Hodgkin disease risk: Role of genetic polymorphisms a nd gene-gene interactions in inflammation pathway genes. (PubMed id 21061265)1, 4 Monroy C.M....El-Zein R.A. (2011)
    61. Combined effects of IL-8 and CXCR2 gene polymorphisms on breast cancer susceptibility and aggressiveness. (PubMed id 20540789)1, 4 Snoussi K....Chouchane L. (2010)
    62. Interleukin-8 -251 A/T gene polymorphism and gastric cancer susceptibility: a meta-analysis of epidemiological studies. (PubMed id 20363644)1, 4 Liu L....Zhou Y. (2010)
    63. The utility and predictive value of combinations of l ow penetrance genes for screening and risk prediction of colorectal cancer. (PubMed id 20437058)1, 4 Hawken S.J....Little J. (2010)
    64. Cytokine gene polymorphisms and risk for upper respir atory symptoms in highly-trained athletes. (PubMed id 20839488)1, 4 Cox A.J....Scott R.J. (2010)
    65. IL-1A9 (+3953 C/T) and IL-8 (-251 A/T) gene polymorphi sms in H. pylori mediated gastric disorders. (PubMed id 20574123)1, 4 Farshad S....Ranjbar R. (2010)
    66. Interleukin-8-251A/T polymorphism and Helicobacter py lori infection influence risk for the development of gastric cardiac adenocarci noma in a high-incidence area of China. (PubMed id 20300863)1, 4 Zhang L....Wang S. (2010)
    67. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (2010)
    68. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    69. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
    70. Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer. (PubMed id 20222161)1, 4 Sugimoto M....Furuta T. (2010)
    71. Polymorphisms in inflammatory genes, plasma antioxida nts, and prostate cancer risk. (PubMed id 20431935)1, 4 Zhang J....Kadlubar F.F. (2010)
    72. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility 'hot-spot'. (PubMed id 20628624)1, 4 Johnatty S.E.... . (2010)
    73. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    74. IL-8 -251A/T polymorphism is associated with decrease d cancer risk among population-based studies: evidence from a meta-analysis. (PubMed id 20400292)1, 4 Gao L.B....Zhang L. (2010)
    75. Association of genetic variants, ethnicity and preter m birth with amniotic fluid cytokine concentrations. (PubMed id 20369436)1, 4 Menon R....Williams S.M. (2010)
    76. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
    77. Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia. (PubMed id 20380014)1, 4 Li Z.W....Li J.Y. (2010)
    78. Joint influences of Acidic-Mammalian-Chitinase with I nterleukin-4 and Toll-like receptor-10 with Interleukin-13 in the genetics of a sthma. (PubMed id 20444155)1, 4 Heinzmann A....Strauch K. (2010)
    79. A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1, 4 Romero R....Menon R. (2010)
    80. Genetic variants in inflammation-related genes are as sociated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626)1, 4 Hildebrandt M.A....Wu X. (2010)
    81. Associations of plasma IL-8 levels with Helicobacter pylori seropositivity, gastric atrophy, and IL-8 T-251A genotypes. (PubMed id 19719901)1, 4 Naito M....Hamajima N. (2010)
    82. The interleukin-8-251 AA genotype is associated with angiogenesis in gastric carcinogenesis in Helicobacter pylori-infected Koreans. (PubMed id 20621718)1, 4 Song J.H....Song I.S. (2010)
    83. Cytokine genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children. (PubMed id 21048327)1, 4 Weng K.P....Ger L.P. (2010)
    84. Association of haplotypes in the IL8 gene with suscep tibility to chronic periodontitis in a Brazilian population. (PubMed id 20488171)1, 4 Kim Y.J....Scarel-Caminaga R.M. (2010)
    85. Common single nucleotide polymorphisms in immunoregul atory genes and multiple myeloma risk among women in Connecticut. (PubMed id 20568250)1, 4 Lee K.M....Lan Q. (2010)
    86. IL-8 -251 T > A polymorphism is associated with bl adder cancer susceptibility and outcome after BCG immunotherapy in a northern I ndian cohort. (PubMed id 20470938)1, 4 Ahirwar D.K....Mittal R.D. (2010)
    87. Polymorphisms in cytokine genes and serum cytokine le vels among New Mexican women with and without breast cancer. (PubMed id 20418110)1, 4 Erdei E....Berwick M. (2010)
    88. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    89. Genetic variations in angiogenesis pathway genes asso ciated with clinical outcome in localized gastric adenocarcinoma. (PubMed id 19622587)1, 4 Lurje G....Lenz H.J. (2010)
    90. Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients. (PubMed id 20217044)1, 4 Gu W....Jiang J.X. (2010)
    91. Polymorphisms in innate immunity genes and patients r esponse to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (2010)
    92. The association of innate immune response gene polymo rphisms and puerperal group A streptococcal sepsis. (PubMed id 20207250)1, 4 Davis S.M....Silver R.M. (2010)
    93. Association of interleukin-8 gene polymorphisms and h aplotypes with oral lichen planus in a Chinese population. (PubMed id 19842025)1, 4 Dan H....Zeng X. (2010)
    94. Association of haplotypes of inflammation-related gen es with gastric preneoplastic lesions in African Americans and Caucasians. (PubMed id 20473875)1, 4 Zabaleta J....Ochoa A.C. (2010)
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    96. Cetuximab as second-line therapy in patients with met astatic esophageal adenocarcinoma: a phase II Southwest Oncology Group Study (S 0415). (PubMed id 20631636)1, 4 Gold P.J....Blanke C.D. (2010)
    97. Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. (PubMed id 20463618)1, 4 Abu-Maziad A....Murray J.C. (2010)
    98. Cardiovascular disease in kidney transplant recipient s: the prognostic value of inflammatory cytokine genotypes. (PubMed id 20061995)1, 4 La Manna G....Stefoni S. (2010)
    99. Common polymorphisms in ITGA2, PON1 and THBS2 are ass ociated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PubMed id 20485444)1, 4 Wang Y....Huang W. (2010)
    100. Interleukin 10 polymorphisms differentially influence the risk of gastric cancer in East Asians and Caucasians. (PubMed id 20363151)1, 4 Won H.H....Lee K.A. (2010)
    101. Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors. (PubMed id 20564140)1, 4 Rausch S.M....Yang P. (2010)
    102. Nontuberculous mycobacterial cervicofacial lymphadeni tis in children from the multicenter, randomized, controlled trial in The Nethe rlands: relevance of polymorphisms in candidate host immunity genes. (PubMed id 20399512)1, 4 Haverkamp M.H....van Dissel J.T. (2010)
    103. A common polymorphism in the interleukin-8 gene promo ter is associated with an increased risk for recurrent Clostridium difficile in fection. (PubMed id 21058913)1, 4 Garey K.W....Dupont H.L. (2010)
    104. Identification of fetal and maternal single nucleotid e polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1, 4 Romero R....Menon R. (2010)
    105. Interleukin 8 -251T>A and Interferon gamma +874A>T polymorphism: Potential predictors of allograft outcome in renal transplant recipients from north India. (PubMed id 19189859)1, 4 Singh R....Mittal R.D. (2009)
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    108. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (2009)
    109. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
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    113. Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis. (PubMed id 19364277)1, 4 Kim Y.J....Scarel-Caminaga R.M. (2009)
    114. Cytokine and cytokine receptor single-nucleotide poly morphisms predict risk for non-small cell lung cancer among women. (PubMed id 19505916)1, 4 Van Dyke A.L....Schwartz A.G. (2009)
    115. Interleukin-8 T-251A polymorphism was associated with positive anti-p53 antibodies in Uzbekistan population. (PubMed id 19994728)1, 4 Okada R....Hamajima N. (2009)
    116. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (2009)
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    119. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    120. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (2009)
    121. Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk. (PubMed id 19246914)1, 4 Li K....Yao L. (2009)
    122. Innate immunity in ocular Chlamydia trachomatis infec tion: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarri ng in Gambians. (PubMed id 20015396)1, 4 Natividad A....Bailey R. (2009)
    123. Racial disparity in pathophysiologic pathways of pret erm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (2009)
    124. Common Variants in Immune and DNA Repair Genes and Risk for Human Papillomavirus Persistence and Progression to Cervical Cancer. (PubMed id 19012493)1, 4 Wang S.S....Hildesheim A. (2009)
    125. Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians. (PubMed id 19357773)1, 4 Ahluwalia T.S....Singal P.K. (2009)
    126. A gene-based risk score for lung cancer susceptibilit y in smokers and ex-smokers. (PubMed id 19789190)1, 4 Young R.P....Gamble G.D. (2009)
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    128. Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: Enhanced elimination of the infection during disease progression? (PubMed id 19427781)1, 4 Gao L....Brenner H. (2009)
    129. Citrullination of CXCL8 increases this chemokine's ab ility to mobilize neutrophils into the blood circulation. (PubMed id 19608678)1, 2 Loos T....Proost P. (2009)
    130. Polymorphisms in inflammation genes, tobacco smoke an d furred pets and wheeze in children. (PubMed id 19674346)1, 4 SA...Raaschou-Nielsen O. (2009)
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    133. Common genetic variants in candidate genes and risk o f familial lymphoid malignancies. (PubMed id 19573080)1, 4 Liang X.S....Goldin L.R. (2009)
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    135. Gene expression polymorphisms of interleukins-1beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma. (PubMed id 18273643)1, 4 Vairaktaris E....Patsouris E. (2008)
    136. A systematic review of meta-analyses on gene polymorp hisms and gastric cancer risk. (PubMed id 19506726)1, 4 Gianfagna F....Boccia S. (2008)
    137. Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885)1, 4 Enjuanes A....Campo E. (2008)
    138. Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease. (PubMed id 18665932)1, 4 Kim N....Song I.S. (2008)
    139. IL-1beta and IL-8, matrix metalloproteinase 3, and pepsinogen secretion before and after H. pylori eradication in gastroduodenal phenotypes. (PubMed id 18609140)1, 4 Won Chang Y....Chang R. (2008)
    140. Genetic polymorphism of MCP-1-2518, IL-8-251 and susceptibility to acute pancreatitis: A pilot study in population of Suzhou, China. (PubMed id 18837094)1, 4 Chen W.C. and Nie J.S. (2008)
    141. Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST). (PubMed id 18628242)1, 4 Crusius J.B....Gonzalez C.A. (2008)
    142. Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. (PubMed id 18549840)1, 4 Enquobahrie D.A....Psaty B.M. (2008)
    143. Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study. (PubMed id 18992148)1, 4 KA1ry S....BAczieau S. (2008)
    144. Association between a pro-inflammatory genetic profile and the risk of chronic atrophic gastritis among older adults from Germany. (PubMed id 19013788)1, 4 Gao L....Brenner H. (2008)
    145. The interleukin-8-251*T/*A polymorphism is not associated with risk for gastric carcinoma development in a Portuguese population. (PubMed id 18090907)1, 4 Canedo P....Machado J.C. (2008)
    146. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (2008)
    147. A pro-inflammatory genotype predisposes to Barrett's esophagus. (PubMed id 18192685)1, 4 Moons L.M....Siersema P.D. (2008)
    148. Association of specific haplotype of TNFalpha with Helicobacter pylori-mediated duodenal ulcer in eastern Indian population. (PubMed id 19147919)1, 4 Chakravorty M....Roychoudhury S. (2008)
    149. Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach. (PubMed id 18284424)1, 4 Infante J....Combarros O. (2008)
    150. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
    151. Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration. (PubMed id 18310311)1, 4 Goverdhan S.V....Lotery A.J. (2008)
    152. Interleukin-10 is associated with resistance to febrile seizures: Genetic association and experimental animal studies. (PubMed id 19055487)1, 4 Ishizaki Y....Hara T. (2008)
    153. Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression. (PubMed id 18628251)1, 4 Cacev T....Kapitanovic S. (2008)
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    157. Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis. (PubMed id 18416756)1, 4 de Jongh C.M....Kezic S. (2008)
    158. The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care. (PubMed id 18990769)1, 4 Reyes-Gibby C.C....Bruera E. (2008)
    159. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (2008)
    160. Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study. (PubMed id 18164040)1, 4 Vogel U....Tjonneland A. (2008)
    161. Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. (PubMed id 18710930)1, 2 Proost P....Van Damme J. (2008)
    162. IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behcet's disease in patients of German or Turkish origin. (PubMed id 19026125)1, 4 Storz K....Kotter I. (2008)
    163. Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. (PubMed id 18633131)1, 4 Habermann T.M....Cerhan J.R. (2008)
    164. A report of cytokine polymorphisms and COPD risk in Xuan Wei, China. (PubMed id 17681858)1, 4 Shen M....Lan Q. (2008)
    165. Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer. (PubMed id 18550579)1, 4 Lurje G....Lenz H.J. (2008)
    166. Association of cytokine gene polymorphisms with rate of decline in lung function. (PubMed id 18545091)1, 4 Yucesoy B....Burgess J.L. (2008)
    167. Candidate genes and cerebral palsy: a population-based study. (PubMed id 18977990)1, 4 Gibson C.S....Nelson K.B. (2008)
    168. Cytokine gene polymorphisms in Italian preterm infants: association between interleukin-10 -1082 G/A polymorphism and respiratory distress syndrome. (PubMed id 17314689)1, 4 Capasso M....Iolascon A. (2007)
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    170. Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes. (PubMed id 17307204)1, 4 Vogel U....Tjonneland A. (2007)
    171. Polymorphisms in genes involved in innate immunity predispose toward mycetoma susceptibility. (PubMed id 17709521)1, 4 van de Sande W.W....van Belkum A. (2007)
    172. Chronic infections and genetic factors in the development of ischemic stroke. (PubMed id 17802898)1, 4 Kis Z....Gonczol E. (2007)
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    174. Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival. (PubMed id 17327408)1, 4 Cerhan J.R....Hartge P. (2007)
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    177. Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract. (PubMed id 17356794)1, 4 Campa D....Canzian F. (2007)
    178. Relevance of transforming growth factor-beta1, interleukin-8, and tumor necrosis factor-alpha polymorphisms in patients with chronic pancreatitis. (PubMed id 17400536)1, 4 Farkas G....Mandi Y. (2007)
    179. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (2007)
    180. Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population. (PubMed id 17336597)1, 4 Watt A.P....Elborn J.S. (2007)
    181. Evidence of potential interaction of chemokine genes in susceptibility to systemic sclerosis. (PubMed id 17599774)1, 4 Lee E.B....Song Y.W. (2007)
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    185. Association of haplotypes of interleukin-10 gene with the risk of cancer. (PubMed id 18457043)1, 4 Pogoda T.V....Govorun V.M. (2007)
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    195. Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity. (PubMed id 16702372)1, 4 Brown E.E....Chanock S.J. (2006)
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    379. Helicobacter pylori induces interleukin-8 secretion by Toll-like receptor 2- and Toll-like receptor 5-dependent and -independent pathways. (PubMed id 15731050)1, 9 Torok A.M....Goldberg J.B. (2005)
    380. [Characteristics of the airway inflammation and the relationship to interleukin-17 in severe asthma] (PubMed id 16207434)1, 9 Zhou Q.T....Yao W.Z. (2005)
    381. Concentration of IL-2, IL-6, IL-8, IL-10 and TNF-alpha in children with acute lymphoblastic leukemia after cessation of chemotherapy. (PubMed id 15152368)1, 9 Mazur B....Janik-Moszant A. (2004)
    382. Cooperative interactions between flagellin and SopE2 in the epithelial interleukin-8 response to Salmonella enterica serovar typhimurium infection. (PubMed id 15321998)1, 9 Huang F.C....Cherayil B.J. (2004)
    383. Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility. (PubMed id 15085176)1, 9 Hacking D....Udalova I.A. (2004)
    384. Differential roles for NF-kappa B in endotoxin and oxygen induction of interleukin-8 in the macrophage. (PubMed id 12909591)1, 9 D'Angio C.T....Finkelstein J.N. (2004)
    385. MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. (PubMed id 15069060)1, 9 Rhee S.H....Pothoulakis C. (2004)
    386. Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. (PubMed id 15534087)1, 9 Benoy I.H....Dirix L.Y. (2004)
    387. Interleukin-8 serum levels in patients with hepatocellular carcinoma: correlations with clinicopathological features and prognosis. (PubMed id 14676125)1, 9 Ren Y....Fan S.T. (2003)
    388. The primary role in biologic activity of the neutrophil chemokines IL-8 and GRO-alpha in cultured nasal epithelial cells. (PubMed id 12744776)1, 9 Rudack C....Schroeder J.M. (2003)
    389. Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. (PubMed id 11854210)1, 9 Tamai R....Takada H. (2002)
    390. Protein kinase C and ERK activation are required for TFF-peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-alpha-induced interleukin-6 (IL-6) and IL-8 secretion. (PubMed id 11884401)1, 9 Graness A....Hoffmann W. (2002)
    391. Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate. (PubMed id 12151344)1, 9 Hellmuth M....Muhl H. (2002)
    392. Interleukin-8 and growth-regulated oncogene alpha mediate angiogenesis in Kaposi's sarcoma. (PubMed id 12388718)1, 9 Lane B.R....Markovitz D.M. (2002)
    393. Autocrine growth effect of IL-8 and GROalpha on a human pancreatic cancer cell line, Capan-1. (PubMed id 10881932)1, 9 Takamori H....Schraufstatter I.U. (2000)
    394. Proinflammatory cytokine IL-1beta stimulates IL-8 syn thesis in mast cells via a leukotriene B4 receptor 2-linked pathway, contributi ng to angiogenesis. (PubMed id 20194723)1, 9 Kim G.Y....Kim J.H. (2010)
    395. Lysophosphatidic acid up-regulates expression of grow th-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protei n-1 in human first-trimester trophoblasts: possible roles in angiogenesis and i mmune regulation. (PubMed id 19906815)1, 9 Chen S.U....Yang Y.S. (2010)
    396. Neutrophil expression of cyclooxygenase 2 in preeclam psia. (PubMed id 20220108)1, 9 Bachawaty T....Walsh S.W. (2010)
    397. Muscarinic M3 receptor stimulation increases cigarett e smoke-induced IL-8 secretion by human airway smooth muscle cells. (PubMed id 19460789)1, 9 Gosens R....Zuyderduyn S. (2009)
    398. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. (PubMed id 18830271)1, 9 Watanabe H....Iijima M. (2009)
    399. [Effects of erythromycin on the synthesis of interleu kin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells] (PubMed id 19567187)1, 9 Yu L. and Ran P.X. (2009)
    400. ELISpot analysis of LPS-stimulated leukocytes: human granulocytes selectively secrete IL-8, MIP-1beta and TNF-alpha. (PubMed id 19358850)1, 9 Smedman C....Paulie S. (2009)
    401. Serum proinflammatory cytokine - interleukin-8 as pos sible infection site marker in preterm deliveries. (PubMed id 19591568)1, 9 Bogavac M.A. and BrkiA8 S. (2009)
    402. Lipoxin A4 inhibits IL-1beta-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells. (PubMed id 19357230)1, 9 Decker Y....Godson C. (2009)
    403. Dynamic changes of interleukin-8 network along the co lorectal adenoma-carcinoma sequence. (PubMed id 19350238)1, 9 Cui G....Florholmen J. (2009)
    404. Effect of sulfasalazine on basal and bacteria-stimulated interleukin-8 production by endocervical epithelial cells. (PubMed id 19239421)1, 9 Peltier M.R....Smulian J.C. (2009)
    405. Role of pro-/anti-inflammatory cytokines and their co rrelation with established risk factors in South Indians with coronary artery d isease. (PubMed id 18796448)1, 9 Rajappa M....Sharma A. (2009)
    406. Ceramide-dependent PP2A regulation of TNF{alpha}-induced IL-8 production in respiratory epithelial cells. (PubMed id 19286927)1, 9 Cornell T.T....Shanley T.P. (2009)
    407. Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB. (PubMed id 19074641)1, 9 Rafiee P....Shaker R. (2009)
    408. Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-kappaB-dependent manner. (PubMed id 18156286)1, 9 Puthia M.K....Tan K.S. (2008)
    409. Inhibition by salmeterol and cilomilast of fluticasone-enhanced IP-10 release in airway epithelial cells. (PubMed id 18259970)1, 9 Reddy P.J....Kelsen S.G. (2008)
    410. Inflammatory-activated microvascular endothelial cells regulate interleukin-8 and monocyte chemoattractant protein-1 expression of A549 cells in a paracrine fashion. (PubMed id 18266131)1, 9 Wendel M....Koch T. (2008)
    411. IL-8 induces imbalances between nitric oxide and endothelin-1, and also between plasminogen activator inhibitor-1 and tissue-type plasminogen activator in cultured endothelial cells. (PubMed id 18023202)1, 9 Cheng M....Chen H. (2008)
    412. Angiogenesis-related growth factors and cytokines in the serum of patients with B non-Hodgkin lymphoma; relation to clinical features and response to treatment. (PubMed id 18190463)1, 9 Passam F.H....Alexandrakis M.G. (2008)
    413. Expression of angiogenesis-related genes regulates different steps in the process of tumor growth and metastasis in human urothelial cell carcinoma of the urinary bladder. (PubMed id 19096229)1, 9 Chikazawa M....Shuin T. (2008)
    414. [The mechanism of inhibition by ginkgolide B on interleukin-8 production induced by 4-hydroxynonenal in bronchial epithelial cells] (PubMed id 18953964)1, 9 Yu L....Ran P.X. (2008)
    415. Interleukin (IL)-17A stimulates IL-8 secretion, cyclooxygensase-2 expression, and cell proliferation of endometriotic stromal cells. (PubMed id 18079209)1, 9 Hirata T....Taketani Y. (2008)
    416. Psychosine-induced apoptosis and cytokine activation in immune peripheral cells of Krabbe patients. (PubMed id 17458901)1, 9 Formichi P....Federico A. (2007)
    417. Haplotype association of IL-8 gene with Behcet's disease. (PubMed id 17257314)1, 9 Lee E.B....Song Y.W. (2007)
    418. Interferon-gamma and bacterial lipopolysaccharide act synergistically on human neutrophils enhancing interleukin-8, interleukin-1beta, tumor necrosis factor-alpha, and interleukin-12 p70 secretion and phagocytosis via upregulation of toll-like receptor 4. (PubMed id 17304101)1, 9 Pearl-Yafe M....Shalit I. (2007)
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    420. Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils. (PubMed id 17550933)1, 9 Maneechotesuwan K....Barnes P.J. (2007)
    421. Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2. (PubMed id 16820307)1, 9 Wang H. and He S. (2006)
    422. Chemokines and incident coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. (PubMed id 16825597)1, 9 Herder C....Koenig W. (2006)
    423. Modulation of neutrophil apoptosis in plasma of patients after orthognathic surgery. (PubMed id 16289597)1, 9 Suzuki R....Nagumo M. (2006)
    424. Interleukin 6 and 8 levels in plasma and fibroblast cultures in psoriasis. (PubMed id 16864908)1, 9 Zalewska A....Sysa-Jedrzejowska A. (2006)
    425. The role of interleukin-8 in cancer cells and microenvironment interaction. (PubMed id 15569594)1, 9 Yuan A....Yang P.C. (2005)
    426. Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein. (PubMed id 16164755)1, 9 Moorman J.P....Krishnaswamy G. (2005)
    427. A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells. (PubMed id 15661856)1, 9 Pae H.O....Chung H.T. (2005)
    428. GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells. (PubMed id 15609321)1, 9 Grzesiak J.J....Bouvet M. (2005)
    429. Inflammatory cytokine and thrombin regulation of interleukin-8 and intercellular adhesion molecule-1 expression in first trimester human decidua. (PubMed id 15914533)1, 9 Lockwood C.J....Schatz F. (2005)
    430. Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. (PubMed id 15641067)1, 9 Cecil D.L.... Liu-Bryan R. (2005)
    431. Cigarette smoke induces IL-8, but inhibits eotaxin and RANTES release from airway smooth muscle. (PubMed id 16029496)1, 9 Oltmanns U....Mitchell J.A. (2005)
    432. Secretion of interleukin-8 by human-derived cell lines infected with Mycobacterium bovis. (PubMed id 15203565)1, 9 Mendez-Samperio P....Garcia-Martinez E. (2004)
    433. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. (PubMed id 14767470)1, 9 Lee L.F....Kung H.J. (2004)
    434. Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain. (PubMed id 15133028)1, 9 Rajagopalan L. and Rajarathnam K. (2004)
    435. IL-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of Shigella-induced colitis. (PubMed id 15356171)1, 9 Singer M. and Sansonetti P.J. (2004)
    436. Nitric oxide differentially regulates pro- and anti-angiogenic markers in DLD-1 colon carcinoma cells. (PubMed id 15063730)1, 9 Hellmuth M....Muhl H. (2004)
    437. Helicobacter pylori heat-shock protein 60 induces inflammatory responses through the Toll-like receptor-triggered pathway in cultured human gastric epithelial cells. (PubMed id 15583145)1, 9 Takenaka R....Oguma K. (2004)
    438. The relationship among serum cytokines, chemokine, nitric oxide, and leptin in children with type 1 diabetes mellitus. (PubMed id 15302608)1, 9 Lo H.C....Wang Y.M. (2004)
    439. Serum cytokine profiles in relapsing polychondritis suggest monocyte/macrophage activation. (PubMed id 15529362)1, 9 Stabler T....Kraus V.B. (2004)
    440. Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis. (PubMed id 15203561)1, 9 Bayraktaroglu T....Borazan A. (2004)
    441. Macrophage migration inhibitory factor up-regulates the expression of interleukin-8 messenger RNA in synovial fibroblasts of rheumatoid arthritis patients: common transcriptional regulatory mechanism between interleukin-8 and interleukin-1beta. (PubMed id 15146413)1, 9 Onodera S....Minami A. (2004)
    442. Distinct cytokine production by lung and blood neutrophils from children with cystic fibrosis. (PubMed id 12547728)1, 9 Corvol H....Clement A. (2003)
    443. Upregulation of interleukin-8 by hypoxia in human ovaries. (PubMed id 14672330)1, 9 Yoshino O....Taketani Y. (2003)
    444. Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-media ted synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein. (PubMed id 12777373)1, 9 Walton K.A....Berliner J.A. (2003)
    445. Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. (PubMed id 12576442)1, 9 Chen J.J....Yang P.C. (2003)
    446. Increased E-selectin, IL-8 and IL-10 gene expression in human skin after minimal trauma. (PubMed id 14714557)1, 9 Takeuchi F....Hall R.P. (2003)
    447. Interrelationships of interleukin-8 with interleukin-1beta and neutrophils in vaginal fluid of healthy and bacterial vaginosis positive women. (PubMed id 12529421)1, 9 Cauci S....Quadrifoglio F. (2003)
    448. Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. (PubMed id 12919697)1, 9 Bendre M.S....Suva L.J. (2003)
    449. Different affinities of glycosaminoglycan oligosaccha rides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites. (PubMed id 11814358)1, 9 Goger B....Kungl A.J. (2002)
    450. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. (PubMed id 12359770)1, 9 Bendre M.S....Suva L.J. (2002)
    451. Cytokine regulation of constitutive production of interleukin-8 and -6 by human pancreatic cancer cell lines and serum cytokine concentrations in patients with pancreatic cancer. (PubMed id 12239630)1, 9 Wigmore S.J....Ross J.A. (2002)
    452. MCP-1, MIP-1, IL-8 and ischemic cerebral tissue enhance human bone marrow stromal cell migration in interface culture. (PubMed id 12186702)1, 9 Wang L....Chopp M. (2002)
    453. Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells. (PubMed id 11876744)1, 9 Lahav M....Chowers Y. (2002)
    454. Raised serum levels of interleukin-8 and interleukin-18 in relation to bone metabolism in endogenous Cushing's syndrome. (PubMed id 11888846)1, 9 Kristo C....Bollerslev J. (2002)
    455. Signals involved in mycobacteria-induced CXCL-8 production by human monocytes. (PubMed id 11911801)1, 9 Mendez-Samperio P....Vazquez A. (2002)
    456. Interleukin-8 stimulates human immunodeficiency virus type 1 replication and is a potential new target for antiretroviral therapy. (PubMed id 11483765)1, 9 Lane B.R....Markovitz D.M. (2001)
    457. Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils. (PubMed id 10820279)1, 9 Luu N.T....Nash G.B. (2000)
    458. Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2. (PubMed id 10734056)1, 9 Richardson R.M....Snyderman R. (2000)
    459. CXC chemokines suppress proliferation of myeloid progenitor cells by activation of the CXC chemokine receptor 2. (PubMed id 9551928)1, 9 Sanchez X....Navarro J. (1998)
    460. Physical association of Gi2alpha with interleukin-8 receptors. (PubMed id 8662698)1, 9 Damaj B.B....Naccache P.H. (1996)
    461. The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. (PubMed id 8702798)1, 9 Ahuja S.K. and Murphy P.M. (1996)
    462. IL-8 induces the locomotion of human IL-2-activated natural killer cells. Involvement of a guanine nucleotide binding (Go) protein. (PubMed id 8381837)1, 9 Sebok K....Maghazachi A.A. (1993)
    463. Human placenta constitutively produces interleukin-8 during pregnancy and enhances its production in intrauterine infection. (PubMed id 1391327)1, 9 Shimoya K....Tanizawa O. (1992)
    464. Constitutive NF-kappaB activity regulates the express ion of VEGF and IL-8 and tumor angiogenesis of human glioblastoma. (PubMed id 20127012)1, 9 Xie T.X....Huang S. (2010)
    465. IL-8 production by macrophages is synergistically enh anced when cigarette smoke is combined with TNF-alpha. (PubMed id 19874800)1, 9 Sarir H....Folkerts G. (2010)
    466. Impaired interleukin-8 chemokine secretion by staphyl ococcus aureus-activated epithelium and T-cell chemotaxis in cystic fibrosis. (PubMed id 19597126)1, 9 Al Alam D....Gangloff S.C. (2010)
    467. Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells. (PubMed id 19733855)1, 9 Choi K.H....Kim K. (2010)
    468. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. (PubMed id 20026745)1, 9 Reeves E.P....McElvaney N.G. (2010)
    469. Pollen-induced oxidative stress influences both innat e and adaptive immune responses via altering dendritic cell functions. (PubMed id 20118277)1, 9 Csillag A....Bacsi A. (2010)
    470. Enteroaggregative Escherichia coli infection induces IL-8 production via activation of mitogen-activated protein kinases and the tra nscription factors NF-kappaB and AP-1 in INT-407 cells. (PubMed id 19898747)1, 9 Khan K....Ghosh S. (2010)
    471. Oxidative stress causes IL8 promoter hyperacetylation in cystic fibrosis airway cell models. (PubMed id 18635816)1, 9 Bartling T.R. and Drumm M.L. (2009)
    472. Low concentrations of LL-37 alter IL-8 production by keratinocytes and bronchial epithelial cells in response to proinflammatory sti muli. (PubMed id 19527294)1, 9 Filewod N.C....Hancock R.E. (2009)
    473. Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling. (PubMed id 19157552)1, 9 Leung K.W....Tombran-Tink J. (2009)
    474. Specific NFkappaB subunit activation and kinetics of cytokine induction in adenoviral keratitis. (PubMed id 20038977)1, 9 Rajaiya J....Chodosh J. (2009)
    475. Targeted knockdown of EGR-1 inhibits IL-8 production and IL-8-mediated invasion of prostate cancer cells through suppressing EGR-1/N F-kappaB synergy. (PubMed id 19837667)1, 9 Ma J....Xiao W. (2009)
    476. Human airway smooth muscle cells from asthmatic indiv iduals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, a nd RNA polymerase II binding to the CXCL8 promoter. (PubMed id 19734226)1, 9 John A.E....Knox A.J. (2009)
    477. Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. (PubMed id 19015376)1, 9 SAcmiramoth N....Chollet-Martin S. (2009)
    478. Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells. (PubMed id 19028451)1, 9 Chung S.W....Kim K. (2009)
    479. Proteasome inactivation promotes p38 mitogen-activate d protein kinase-dependent phosphatidylinositol 3-kinase activation and increas es interleukin-8 production in retinal pigment epithelial cells. (PubMed id 19570915)1, 9 Fernandes A.F....Shang F. (2009)
    480. MicroRNAs miR-146a/b negatively modulate the senescen ce-associated inflammatory mediators IL-6 and IL-8. (PubMed id 20148189)1, 9 Bhaumik D....Campisi J. (2009)
    481. Inflammatory cytokine mRNA detection by real time PCR in chorioamniotic membranes from pregnant women with preterm premature rupture of membranes. (PubMed id 19272692)1, 9 Polettini J....Silva M.G. (2009)
    482. Cross talk initiated by endothelial cells enhances mi gration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt /ERK signaling. (PubMed id 19484147)1, 9 Neiva K.G....NAPr J.E. (2009)
    483. Gonadotropin-releasing hormone-regulated chemokine ex pression in human placentation. (PubMed id 19369450)1, 9 Cavanagh P.C....Babwah A.V. (2009)
    484. 15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 a nd GM-CSF in a human airway epithelial cell line (NCI-H292). (PubMed id 19494510)1, 9 Chiba T....Chihara J. (2009)
    485. N-methyl-D-aspartate and sigma-ligands change the production of interleukins 8 and 10 in lymphocytes through modulation of the NMDA glutamate receptor. (PubMed id 19246943)1, 9 Kvaratskhelia E....Mikeladze D.G. (2009)
    486. [Association between interleukin-8 in lung tissues an d stages of chronic obstructive pulmonary diseases] (PubMed id 19950606)1, 9 Hu X.R....Wen F.Q. (2009)
    487. [The role of CyPA in chemotaxis of neutrophil in rheumatoid arthritis and secretion of interleukin-8.] (PubMed id 19426598)1, 9 Zhang B....Zhu P. (2009)
    488. Interleukin-8 is essential for normal urothelial cell survival. (PubMed id 19535567)1, 9 Tseng-Rogenski S. and Liebert M. (2009)
    489. Identification of NR4A2 as a transcriptional activato r of IL-8 expression in human inflammatory arthritis. (PubMed id 19732956)1, 9 Aherne C.M....Murphy E.P. (2009)
    490. The prolyl isomerase Pin1 regulates the NF-kappaB sig naling pathway and interleukin-8 expression in glioblastoma. (PubMed id 19668231)1, 9 Atkinson G.P....Benveniste E.N. (2009)
    491. Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. (PubMed id 19229069)1, 9 Hastings N.E....Blackman B.R. (2009)
    492. Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naA^ve ulcerative colitis during active and quiescent disease. (PubMed id 18942752)1, 9 Matsuda R....Umemura S. (2009)
    493. Osteoblasts derived from osteophytes produce interleu kin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis. (PubMed id 19333684)1, 9 Sakao K....Kubo T. (2009)
    494. Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signalin g pathways. (PubMed id 19608729)1, 9 Wanninger J....Buechler C. (2009)
    495. Tristetraprolin regulates IL-8 mRNA stability in cyst ic fibrosis lung epithelial cells. (PubMed id 19363120)1, 9 Balakathiresan N.S....Biswas R. (2009)
    496. Regulation of chemokine gene expression by hypoxia vi a cooperative activation of NF-kappaB and histone deacetylase. (PubMed id 19446037)1, 9 Safronova O....Morita I. (2009)
    497. [Acute inflammation phase reactants and interleukin-8 in myocardial infarction] (PubMed id 19514335)1, 9 Zorin N.A....Riabicheva T.G. (2009)
    498. Serum interleukin-8 levels are elevated in patients with ovarian endometrioma. (PubMed id 18635170)1, 9 Ohata Y....Terakawa N. (2008)
    499. Differential signaling mechanisms of HNP-induced IL-8 production in human lung epithelial cells and monocytes. (PubMed id 17786963)1, 9 Syeda F....Zhang H. (2008)
    500. The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis. (PubMed id 19046427)1, 9 Govindaraju V....Martin J.G. (2008)
    501. Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. (PubMed id 18307536)1, 9 Li M....Yao Q. (2008)
    502. Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts. (PubMed id 18501560)1, 9 Tong K.M....Tang C.H. (2008)
    503. PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. (PubMed id 18854173)1, 9 Tanaka Y....Kawabata A. (2008)
    504. Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. (PubMed id 18395088)1, 9 Subramaniam D....Anant S. (2008)
    505. Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells. (PubMed id 18678662)1, 9 Snoeks L....Savkovic S.D. (2008)
    506. Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway. (PubMed id 18789871)1, 9 Wurm S....Buechler C. (2008)
    507. Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. (PubMed id 18252714)1, 9 Bhattacharyya S....Tobacman J.K. (2008)
    508. The local cytokine and chemokine milieu within malignant effusions. (PubMed id 18515987)1, 9 Atanackovic D....Bokemeyer C. (2008)
    509. Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10. (PubMed id 18054497)1, 9 Petit-Bertron A.F....Adib-Conquy M. (2008)
    510. Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells. (PubMed id 17854923)1, 9 Moriyuki K....Kawabata A. (2008)
    511. Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells. (PubMed id 18211687)1, 9 Guillot L....Qureshi S.T. (2008)
    512. Osteopontin and interleukin-8 expression is independently associated with prostate cancer recurrence. (PubMed id 18593988)1, 9 Caruso D.J....Lokeshwar B.L. (2008)
    513. Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes. (PubMed id 18599499)1, 9 Gray J.S....Pestka J.J. (2008)
    514. Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4. (PubMed id 18031543)1, 9 Voelcker V....Simon J. (2008)
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    517. IL-8 and p53 are inversely regulated through JNK, p38 and NF-kappaB p65 in HepG2 cells during an inflammatory response. (PubMed id 18607537)1, 9 Rasmussen M.K....Gesser B. (2008)
    518. Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: Potential mechanism for excessive IL-8 expression. (PubMed id 17936667)1, 9 Boncoeur E....Tabary O. (2008)
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    520. Bronchoalveolar cellularity and interleukin-8 levels in measles bronchiolitis obliterans. (PubMed id 17494793)1, 9 Koh Y.Y....Kim C.K. (2007)
    521. Increased serum levels of CXCL8 chemokine in acute toxoplasmic retinochoroiditis. (PubMed id 17488320)1, 9 Goncalves R.M....Teixeira A.L. (2007)
    522. Regulation of interleukin-8 via an airway epithelial signaling cascade. (PubMed id 17220369)1, 9 Nakanaga T....Shao M.X. (2007)
    523. Anti-IL-8 autoantibody:IL-8 immune complexes suppress spontaneous apoptosis of neutrophils. (PubMed id 17513455)1, 9 Fudala R....Kurdowska A.K. (2007)
    524. Uterine cervical inflammatory cytokines, interleukin-6 and -8, as predictors of miscarriage in recurrent cases. (PubMed id 17845205)1, 9 Hattori Y....Sugiura-Ogasawara M. (2007)
    525. Helicobacter pylori environmental interactions: effect of acidic conditions on H. pylori-induced gastric mucosal interleukin-8 production. (PubMed id 17517062)1, 9 Choi I.J....Yamaoka Y. (2007)
    526. Helicobacter pylori heat-shock protein 60 induces interleukin-8 via a Toll-like receptor (TLR)2 and mitogen-activated protein (MAP) kinase pathway in human monocytes. (PubMed id 17244794)1, 9 Zhao Y....Oguma K. (2007)
    527. Bcl10 mediates LPS-induced activation of NF-kappaB and IL-8 in human intestinal epithelial cells. (PubMed id 17540779)1, 9 Bhattacharyya S....Tobacman J.K. (2007)
    528. Stored packed red blood cell transfusion up-regulates inflammatory gene expression in circulating leukocytes. (PubMed id 17592301)1, 9 Escobar G.A....Banerjee A. (2007)
    529. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. (PubMed id 17022986)1, 9 Abe Y....Ballantyne C.M. (2007)
    530. Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. (PubMed id 17466952)1, 9 Verhaeghe C....Bours V. (2007)
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    532. Chemokine signaling specificity: essential role for the N-terminal domain of chemokine receptors. (PubMed id 17630697)1, 9 Prado G.N....Navarro J. (2007)
    533. Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB. (PubMed id 16928771)1, 9 Chiu T.T....Rozengurt E. (2007)
    534. Calcium-calmodulin mediates house dust mite-induced ERK activation and IL-8 production in human respiratory epithelial cells. (PubMed id 17268170)1, 9 Sohn M.H....Kim K.E. (2007)
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    536. Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets. (PubMed id 17908789)1, 9 Winzen R....Holtmann H. (2007)
    537. Azithromycin suppresses activation of nuclear factor-kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants. (PubMed id 17667842)1, 9 Aghai Z.H....Rahman I. (2007)
    538. HtpG, the Porphyromonas gingivalis HSP-90 homologue, induces the chemokine CXCL8 in human monocytic and microvascular vein endothelial cells. (PubMed id 17346315)1, 9 Shelburne C.E....Lopatin D.E. (2007)
    539. Correlation of IL-8 with induction, progression and metastatic potential of colorectal cancer. (PubMed id 17854143)1, 9 Rubie C....Schilling M.K. (2007)
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    541. IL-8 and IDO expression by human gingival fibroblasts via TLRs. (PubMed id 17202379)1, 9 Mahanonda R....Pichyangkul S. (2007)
    542. Induction of urokinase-type plasminogen activator, interleukin-8 and early growth response-1 by STI571 through activating mitogen activated protein kinase in human small cell lung cancer cells. (PubMed id 17581316)1, 9 Yoshida C....Tanimoto M. (2007)
    543. Pneumocystis-mediated IL-8 release by macrophages requires coexpression of mannose receptors and TLR2. (PubMed id 17020928)1, 9 Tachado S.D....Koziel H. (2007)
    544. Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C. (PubMed id 16491014)1, 9 Matsubara M....Hasegawa K. (2006)
    545. Low-density lipoprotein modified by macrophage-derived lysosomal hydrolases induces expression and secretion of IL-8 via p38 MAPK and NF-kappaB by human monocyte-derived macrophages. (PubMed id 16973972)1, 9 Hakala J.K....Pentikainen M.O. (2006)
    546. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. (PubMed id 16541418)1, 9 Lu S. and Dong Z. (2006)
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    548. Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria. (PubMed id 16794530)1, 9 Ciszek M....Mucha K. (2006)
    549. Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure. (PubMed id 16251188)1, 9 Dobreva I....Widmann C. (2006)
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    567. Cyclic mechanical stretch augments both interleukin-8 and monocyte chemotactic protein-3 production in the cultured human uterine cervical fibroblast cells. (PubMed id 15194816)1, 9 Takemura M....Fujii S. (2004)
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    654. Innate immune dysfunction is associated with enhanced disease severity in infants with severe respiratory syncytial virus bronchioliti s. (PubMed id 23204162)1 Mella C....Mejias A. (2013)
    655. Lentivirus-mediated ADAM17 RNA interference inhibited interleukin-8 expression via EGFR signaling in lung epithelial cells. (PubMed id 21932060)1 Li Y....Xia Y. (2012)
    656. Imatinib treatment inhibit IL-6, IL-8, NF-KB and AP-1 production and modulate intracellular calcium in CML patients. (PubMed id 21938724)1 Ciarcia R....Giordano A. (2012)
    657. Oncogenic KRAS-induced interleukin-8 overexpression pr omotes cell growth and migration and contributes to aggressive phenotypes of non -small cell lung cancer. (PubMed id 21544811)1 Sunaga N....Mori M. (2012)
    658. Bronchial hyperresponsiveness in seasonal allergic rhi nitis patients is associated with increased IL-18 during natural pollen exposure . (PubMed id 22819246)1 Kurt E....Alatas O. (2012)
    659. Interleukin-8 and its receptor CXCR2 in the tumour mic roenvironment promote colon cancer growth, progression and metastasis. (PubMed id 22617157)1 Lee Y.S....Hong Y.K. (2012)
    660. HIV-1 Tat protein impairs adipogenesis and induces the expression and secretion of proinflammatory cytokines in human SGBS adipocytes. (PubMed id 22301094)1 Diaz-Delfin J....Villarroya F. (2012)
    661. AP-1 and NF-kB transcriptionally regulate interleukin- 8 in EA.Hy926 cells under shear stress. (PubMed id 21895606)1 Zhang Y....Liu Y.F. (2012)
    662. [High-mobility group box protein 1 in synergy with int erleukin-1b promotes interleukin-8 expression in human airway epithelial cells i n vitro]. (PubMed id 23268406)1 Zhang D....Cai S. (2012)
    663. Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer. (PubMed id 22695075)1 Reis S.T....Dall'Oglio M.F. (2012)
    664. Nox4 mediates renal cell carcinoma cell invasion throu gh hypoxia-induced interleukin 6- and 8- production. (PubMed id 22303451)1 Fitzgerald J.P....Block K. (2012)
    665. IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer. (PubMed id 22783581)1 Kargi A....Gorczynski R.M. (2012)
    666. Cord blood levels of IL-6, IL-8 and IL-10 may be early predictors of bronchopulmonary dysplasia in preterm newborns small for gestatio nal age. (PubMed id 22710869)1 Rocha G....Guimaraes H. (2012)
    667. Interleukin-8 in the pathogenesis of primary central n ervous system lymphoma in association with HIV infection. (PubMed id 22664113)1 Sasakawa A....Maeda Y. (2012)
    668. siRNA high-throughput kinase library screen identifies protein kinase, DNA-activated catalytic polypeptide to play a role in MyD88-ind uced IFNA2 activation and IL-8 secretion. (PubMed id 22332739)1 Charlaftis N....Morley P.J. (2012)
    669. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    670. Modulatory effect of fenofibrate on endothelial produc tion of neutrophil chemokines IL-8 and ENA-78. (PubMed id 22274300)1 Price E.T....Zineh I. (2012)
    671. The expression of interleukin (IL)-6, IL-8, and their receptors in fallopian tubes with ectopic tubal gestation. (PubMed id 22763101)1 Balasubramaniam E.S....El-Bahrawy M. (2012)
    672. Regulation of CXCL8/IL-8 expression by zonula occluden s-1 in human breast cancer cells. (PubMed id 22064657)1 Brysse A....Gilles C. (2012)
    673. H. pylori induces the expression of Hath1 in gastric e pithelial cells via interleukin-8/STAT3 phosphorylation while suppressing Hes1. (PubMed id 22786753)1 Zhang X....Wang R. (2012)
    674. Neuronal apoptosis by HIV-1 Vpr: contribution of proin flammatory molecular networks from infected target cells. (PubMed id 22727020)1 Guha D....Ayyavoo V. (2012)
    675. Interleukin-8 is associated with adhesion, migration a nd invasion in human gastric cancer SCG-7901 cells. (PubMed id 21191670)1 Ju D....Wei P. (2012)
    676. Interleukin-8 gene regulation in epithelial cells by V ibrio cholerae: role of multiple promoter elements, adherence and motility of ba cteria and host MAPKs. (PubMed id 22348317)1 Sarkar M....Chaudhuri K. (2012)
    677. Association of matrix metalloproteinase (MMP)-1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chroni c periodontitis in a Chinese population. (PubMed id 22819245)1 Li G....Chow L.W. (2012)
    678. [Influence of IFN on expression of chemokine receptor CXCR1, CXCR2 and their ligand IL-8 in the patients with chronic hepatitis B]. (PubMed id 22482416)1 Bi H.J....Liu J.H. (2012)
    679. The role of MAPK and Nrf2 pathways in ketanserin-elici ted attenuation of cigarette smoke-induced IL-8 production in human bronchial ep ithelial cells. (PubMed id 22048642)1 Lau W.K....Mak J.C. (2012)
    680. Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginali s-derived secretory products. (PubMed id 22215047)1 Nam Y.H....Shin M.H. (2012)
    681. Correlation of angiogenic cytokines-leptin and IL-8 in stage, type and presentation of endometriosis. (PubMed id 21848410)1 Malhotra N....Kumar S. (2012)
    682. Interleukin 8 gene 2767 A/G polymorphism is associated with increased risk of nephritis in children with Henoch-Schonlein purpura. (PubMed id 21240497)1 Tabel Y....Berdeli A. (2012)
    683. Impact of interleukin-8 gene polymorphisms and environ mental factors on oral cancer susceptibility in Taiwan. (PubMed id 22151543)1 Liu C.M....Chien M.H. (2012)
    684. GEF-H1-RhoA signaling pathway mediates LPS-induced NF- kB transactivation and IL-8 synthesis in endothelial cells. (PubMed id 22226472)1 Guo F....Huan J. (2012)
    685. Effect of Helicobacter pylori cdrA on interleukin-8 se cretions and nuclear factor kappa B activation. (PubMed id 22346248)1 Takeuchi H....Sugiura T. (2012)
    686. Chemokines as markers of local inflammation and angiog enesis in patients with chronic subdural hematoma: a prospective study. (PubMed id 22037980)1 Stanisic M....Saehle T. (2012)
    687. Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells. (PubMed id 22080750)1 Aso H....Hasegawa Y. (2012)
    688. Insulin-like growth factor-1 cytokines cross-talk in t ype 1 diabetes mellitus: relationship to microvascular complications and bone mi neral density. (PubMed id 22513191)1 AboElAsrar M.A....Omar A.M. (2012)
    689. Association of serum levels of polychlorinated bipheny ls with IL-8 mRNA expression in blood samples from asthmatic and non-asthmatic J apanese children. (PubMed id 22326254)1 Tsuji M....Matsumura F. (2012)
    690. Findings related to IL-8 and IL-10 gene polymorphisms in a Mexican patient population with irritable bowel syndrome infected with Blas tocystis. (PubMed id 22287022)1 Olivo-Diaz A....Maravilla P. (2012)
    691. Upregulation of chemokines and their receptors in Duch enne muscular dystrophy: potential for attenuation of myofiber necrosis. (PubMed id 23225384)1 De Paepe B....De Bleecker J.L. (2012)
    692. Interleukin-8 and -10 gene polymorphisms in irritable bowel syndrome. (PubMed id 22740130)1 Romero-Valdovinos M....Olivo-Diaz A. (2012)
    693. Effect of berberine on proinflammatory cytokine produc tion by ARPE-19 cells following stimulation with tumor necrosis factor-a. (PubMed id 22427564)1 Wang Q....Yang P. (2012)
    694. High TNF-alpha and IL-8 levels predict low blood dendr itic cell counts in primary cytomegalovirus infection. (PubMed id 22257833)1 Varani S....Soderberg-Naucler C. (2012)
    695. Protein kinase A enhances lipopolysaccharide-induced I L-6, IL-8, and PGE_2 production by human gingival fibroblasts. (PubMed id 22452847)1 Ara T....Miyazawa H. (2012)
    696. Interleukin 6 and interleukin 8 play important roles i n systemic inflammatory response syndrome of meconium peritonitis. (PubMed id 22068677)1 Kanamori Y....Iwanaka T. (2012)
    697. Oncostatin M decreases interleukin-1 b secretion by hu man synovial fibroblasts and attenuates an acute inflammatory reaction in vivo. (PubMed id 21854541)1 Dumas A....Pouliot M. (2012)
    698. Association of interleukin-6 and interleukin-8 with po or prognosis in elderly patients with chronic lymphocytic leukemia. (PubMed id 22475215)1 Yoon J.Y....Johnston J.B. (2012)
    699. Vitiligo-inducing phenols activate the unfolded protei n response in melanocytes resulting in upregulation of IL6 and IL8. (PubMed id 22696056)1 Toosi S....Manga P. (2012)
    700. Low vascular endothelial growth factor and interleukin -8 in cerebrospinal fluid of suicide attempters. (PubMed id 23168996)1 Isung J....Jokinen J. (2012)
    701. The ORF2 glycoprotein of hepatitis E virus inhibits ce llular NF-kB activity by blocking ubiquitination mediated proteasomal degradatio n of IkBa in human hepatoma cells. (PubMed id 22590978)1 Surjit M....Lal S.K. (2012)
    702. Cytokines induced neutrophil extracellular traps forma tion: implication for the inflammatory disease condition. (PubMed id 23110185)1 Keshari R.S....Dikshit M. (2012)
    703. Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed im mune reconstitution inflammatory syndrome during ACTG A5164. (PubMed id 23002445)1 Grant P.M....Sereti I. (2012)
    704. HIV-1 matrix protein p17 binds to the IL-8 receptor CX CR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activat ion. (PubMed id 22262769)1 Giagulli C....Caruso A. (2012)
    705. Serial examination of serum IL-8, IL-10 and IL-1Ra lev els is significant in neonatal seizures induced by hypoxic-ischaemic encephalopa thy. (PubMed id 22537067)1 Youn Y.A....Lee I.G. (2012)
    706. Bradykinin- and lipopolysaccharide-induced bradykinin B2 receptor expression, interleukin 8 release and 'nitrosative stress' in bronchial epithelial cells BEAS-2B: role for neutrophils. (PubMed id 22935637)1 Ricciardolo F.L....De Rose V. (2012)
    707. DNA promoter methylation status and protein expression of interleukin-8 in human colorectal adenocarcinomas. (PubMed id 22108905)1 Dimberg J....Matussek A. (2012)
    708. Chios mastic fractions in experimental colitis: implic ation of the nuclear factor kB pathway in cultured HT29 cells. (PubMed id 22891614)1 Papalois A....Andrikopoulos N.K. (2012)
    709. Astaxanthin attenuates the UVB-induced secretion of pr ostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 pho sphorylation in a ROS depletion-independent manner. (PubMed id 22626465)1 Terazawa S....Imokawa G. (2012)
    710. Suppression of MIP-2 or IL-8 production by annexins A1 and A4 during coculturing of macrophages with late apoptotic human peripheral b lood neutrophils. (PubMed id 22056994)1 Iwasa T....Kobayashi Y. (2012)
    711. Double-stranded RNA induces IL-8 and MCP-1 gene expres sion via TLR3 in HaCaT-keratinocytes. (PubMed id 22762377)1 Voss A....Kerkhoff C. (2012)
    712. Ovarian endometrioma but not deep infiltrating endomet riosis is associated with increased serum levels of interleukin-8 and interleuki n-6. (PubMed id 22819248)1 Carmona F....Balasch J. (2012)
    713. Upregulation of IL-6, IL-8 and CXCL-1 production in de rmal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemi cal and transcriptomic analyses. (PubMed id 23043537)1 Kolar M....Smetana K. (2012)
    714. The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer. (PubMed id 22741617)1 Walczak A....Majsterek I. (2012)
    715. Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cells. (PubMed id 22248188)1 Eftang L.L....Bukholm G. (2012)
    716. Characterization of the interaction of interleukin-8 w ith hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivat ives by spectroscopy and molecular modeling. (PubMed id 21873605)1 Pichert A....Pisabarro M.T. (2012)
    717. Adipose tissue IL-8 is increased in normal weight wome n after menopause and reduced after gastric bypass surgery in obese women. (PubMed id 22168600)1 Alvehus M....Olsson T. (2012)
    718. Gravity-sensitive signaling drives 3-dimensional forma tion of multicellular thyroid cancer spheroids. (PubMed id 22964303)1 Grosse J....Grimm D. (2012)
    719. Interleukin-8 associates with adhesion, migration, inv asion and chemosensitivity of human gastric cancer cells. (PubMed id 22408359)1 Kuai W.X....Tang X.J. (2012)
    720. Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians. (PubMed id 22690076)1 Mustapha M.A....Ankathil R. (2012)
    721. Src homology-2 domain-containing protein tyrosine phos phatase (SHP) 2 and p38 regulate the expression of chemokine CXCL8 in human astr ocytes. (PubMed id 23029125)1 Mamik M.K. and Ghorpade A. (2012)
    722. 25-Hydroxycholesterol enhances cytokine release and To ll-like receptor 3 response in airway epithelial cells. (PubMed id 22849850)1 Koarai A....Ichinose M. (2012)
    723. BLCA-4 expression is related to MMP-9, VEGF, IL-1a and IL-8 in bladder cancer but not to PEDF, TNF-a or angiogenesis. (PubMed id 22197408)1 Feng C....Ding Q. (2012)
    724. ALK+ALCLs induce cutaneous, HMGB-1-dependent IL-8/CXCL 8 production by keratinocytes through NF-kB activation. (PubMed id 22394598)1 Dejean E....Meggetto F. (2012)
    725. An immunohistochemical study of interleukin-8 (IL-8) i n breast cancer. (PubMed id 22244449)1 Zuccari D.A....Esteves J.L. (2012)
    726. Comparative levels of macrophage migration inhibitory factor, procalcitonin, osteoprotegerin, interleukin-8, hs-C reactive protein, D- dimer in febrile neutropenia, newly diagnosed cancer patients, and infectious fe ver. (PubMed id 22079264)1 Bilgir O....Isikyakar T. (2012)
    727. CCR1-mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive G a(14/16) signaling and IL-6 release. (PubMed id 23125416)1 Lee M.M....Wong Y.H. (2012)
    728. MK2 posttranscriptionally regulates TNF-a-induced expression of ICAM-1 and IL-8 via tristetraprolin in human pulmonary microvascular e ndothelial cells. (PubMed id 22268119)1 Shi J.X....Shi Y. (2012)
    729. Genetic variations of interleukin-8, CXCR1 and CXCR2 g enes and risk of acute pyelonephritis in children. (PubMed id 22325052)1 Javor J....Liptakova A. (2012)
    730. Role of mechanical stretching and lipopolysaccharide i n early apoptosis and IL-8 of alveolar epithelial type II cells A549. (PubMed id 22840453)1 Ning Q.M....Zhao X.K. (2012)
    731. Association of the CagA gene positive Helicobacter pyl ori and tissue levels of interleukin-17 and interleukin-8 in gastric ulcer patie nts. (PubMed id 23888551)1 El-Fakhry A.A....El-Naggar M.M. (2012)
    732. Native X-DING-CD4 protein secreted by HIV-1 resistant CD4+ T cells blocks activity of IL-8 promoter in human endothelial cells infecte d with enteric bacteria. (PubMed id 22031506)1 Ivanova A....Simm M. (2012)
    733. Trefoil factor 3 isolated from human breast milk downr egulates cytokines (IL8 and IL6) and promotes human beta defensin (hBD2 and hBD4 ) expression in intestinal epithelial cells HT-29. (PubMed id 23198942)1 Barrera G.J....Gonzalez J.E. (2012)
    734. An NF-kB-independent and Erk1/2-dependent mechanism co ntrols CXCL8/IL-8 responses of airway epithelial cells to cadmium. (PubMed id 22094458)1 Cormet-Boyaka E....Boyaka P.N. (2012)
    735. Residue 75 of interleukin-8 is crucial for its interac tions with glycosaminoglycans. (PubMed id 23070988)1 Nordsieck K....Beck-Sickinger A.G. (2012)
    736. BLT2 up-regulates interleukin-8 production and promote s the invasiveness of breast cancer cells. (PubMed id 23145117)1 Kim H....Kim J.H. (2012)
    737. IL-8 from local subcutaneous wounds regulates CD11b ac tivation. (PubMed id 22229891)1 Lundahl J....Paulsson J.M. (2012)
    738. Elevated serum IL-8 is associated with the presence of hepatocellular carcinoma and independently predicts survival. (PubMed id 23072563)1 Welling T.H....Marrero J.A. (2012)
    739. Enhanced chemosensitization in multidrug-resistant hum an breast cancer cells by inhibition of IL-6 and IL-8 production. (PubMed id 22923236)1 Shi Z....Huang R.P. (2012)
    740. Thymidine phosphorylase enhances reactive oxygen speci es generation and interleukin-8 expression in human cancer cells. (PubMed id 22751949)1 Tabata S....Akiyama S. (2012)
    741. Serum biomarkers are similar in Churg-Strauss syndrome and hypereosinophilic syndrome. (PubMed id 22775568)1 Khoury P....Klion A.D. (2012)
    742. Increased interleukin-8 in epithelial lining fluid of collapsed lungs during one-lung ventilation for thoracotomy. (PubMed id 22821380)1 Komatsu Y....Koizumi T. (2012)
    743. Effects of interleukin-8 on estradiol and progesterone production by bovine granulosa cells from large follicles and progesterone prod uction by luteinizing granulosa cells in culture. (PubMed id 22129622)1 Shimizu T....Miyamoto A. (2012)
    744. Serum levels of Th17 associated cytokines in chronic h epatitis C virus infection. (PubMed id 22748467)1 Sousa G.M....Atta A.M. (2012)
    745. Adhesive interaction between peripheral blood mononucl ear cells and activated platelets in the presence of anti-human leukocyte antige n Class I alloantibody causes production of IL-1b and IL-8. (PubMed id 21923858)1 Takahashi D....Ikeda H. (2012)
    746. Morphological analysis and interleukin release in huma n gingival fibroblasts seeded on different denture base acrylic resins. (PubMed id 23058014)1 Trubiani O....Caputi S. (2012)
    747. Lack of association between interleukin-8-251 T>A p olymorphism and colorectal cancer risk: a meta-analysis based on 3,019 cases and 3,984 controls. (PubMed id 23244113)1 Hu L.X....Pan Y.Y. (2012)
    748. Identification by DNA microarray of genes involved in Candida albicans-treated gingival epithelial cells. (PubMed id 22553989)1 Ikuta T....Abiko Y. (2012)
    749. Inverse relationship between PSA and IL-8 in prostate cancer: an insight into a NF-kB-mediated mechanism. (PubMed id 22403723)1 Xu Y....St Clair W.H. (2012)
    750. Pathogenesis of prostatic small cell carcinoma involve s the inactivation of the P53 pathway. (PubMed id 22389383)1 Chen H....Huang J. (2012)
    751. AA genotype of IL-8 -251A/T is associated with low PaO (2)/FiO(2) in critically ill patients and with increased IL-8 expression. (PubMed id 22897124)1 Wacharasint P....Walley K.R. (2012)
    752. Gene polymorphisms of NOD1 and interleukin-8 influence the susceptibility to erosive esophagitis in Helicobacter pylori infected Japan ese population. (PubMed id 22902391)1 Oikawa T....Shimosegawa T. (2012)
    753. Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2. (PubMed id 23029099)1 Dwyer J....Gavard J. (2012)
    754. Met receptor tyrosine kinase signaling induces secreti on of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer. (PubMed id 22815748)1 Hill K.S....Elferink L.A. (2012)
    755. CXCL8 enhances proliferation and growth and reduces ap optosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggere d PTEN/AKT signal pathway. (PubMed id 22563025)1 Li M.Q....Li D.J. (2012)
    756. Secretion of IL-6 and IL-8 from lysophosphatidic acid- stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone res orption. (PubMed id 21925926)1 Hwang Y.S....Chung W.Y. (2012)
    757. Lysophosphatidic acid receptor 2/3-mediated IL-8-depen dent angiogenesis in cervical cancer cells. (PubMed id 21964883)1 Chen R.J....Lin M.C. (2012)
    758. Reduced nuclear factor-kB repressing factor: a link to ward systemic inflammation in COPD. (PubMed id 22441735)1 Lee K.Y....Kuo H.P. (2012)
    759. miR-16 targets transcriptional corepressor SMRT and mo dulates NF-kappaB-regulated transactivation of interleukin-8 gene. (PubMed id 22292036)1 Zhou R....Chen X.M. (2012)
    760. Lack of association of -251T/A polymorphism in interle ukin 8 gene with susceptibility to obsessive-compulsive disorder in Chinese Han population. (PubMed id 22609211)1 Liu S....Ma X. (2012)
    761. The diagnostic value of interleukin-6 and interleukin- 8 for early prediction of bacteremia and sepsis in children with febrile neutrop enia and cancer. (PubMed id 22367386)1 Urbonas V....Tamuliene I. (2012)
    762. Prostaglandin E2 modulates IL-8 expression through for mation of a multiprotein enhanceosome in human colonic epithelial cells. (PubMed id 22531917)1 Srivastava V....Chadee K. (2012)
    763. Up-regulation of chemokine C-C ligand 2 (CCL2) and C- X-C chemokine 8 (CXCL8) expression by monocytes in chronic idiopathic urticaria . (PubMed id 22132892)1 Santos J.C....Sato M.N. (2012)
    764. The monomer-dimer equilibrium and glycosaminoglycan in teractions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment. (PubMed id 22140266)1 Gangavarapu P....Rajarathnam K. (2012)
    765. Lipopolysaccharide induces cytokine production and dec reases extravillous trophoblast invasion through a mitogen-activated protein kin ase-mediated pathway: possible mechanisms of first trimester placental dysfuncti on. (PubMed id 22052387)1 Anton L....Elovitz M.A. (2012)
    766. The IL-8 gene polymorphisms and the risk of the hepati tis B virus/infected patients. (PubMed id 22335768)1 Qin X....Li S. (2012)
    767. Effect of Helicobacter pylori eradication according to the IL-8-251 polymorphism in Koreans. (PubMed id 23091318)1 Kang H.Y....Song I.S. (2012)
    768. Evidence of central inflammation in fibromyalgia-incre ased cerebrospinal fluid interleukin-8 levels. (PubMed id 22126705)1 Kadetoff D....Kosek E. (2012)
    769. Suppression of IL-8 production in gastric epithelial c ells by MUC1 mucin and peroxisome proliferator-associated receptor-g. (PubMed id 22766852)1 Park Y.S....Lillehoj E.P. (2012)
    770. Induction of interleukin-8 by Naegleria fowleri lysate s requires activation of extracellular signal-regulated kinase in human astrogli al cells. (PubMed id 22411631)1 Kim J.H....Shin H.J. (2012)
    771. Upregulation of thromboxane synthase mediates visfatin -induced interleukin-8 expression and angiogenic activity in endothelial cells. (PubMed id 22293189)1 Kim S.R....Bae M.K. (2012)
    772. Peroxisome proliferating activating receptor gamma-ind ependent attenuation of interleukin 6 and interleukin 8 secretion from primary e ndometrial stromal cells by thiazolidinediones. (PubMed id 22192353)1 McKinnon B....Mueller M.D. (2012)
    773. NFkB and AP-1 drive human myometrial IL8 expression. (PubMed id 22685373)1 Khanjani S....Bennett P.R. (2012)
    774. The expression of interleukin-8 and interleukin-8 rece ptors in endometrial carcinoma. (PubMed id 22626766)1 Ewington L....El-Bahrawy M.A. (2012)
    775. Angiopoietin-1 but not angiopoietin-2 induces IL-8 syn thesis and release by human neutrophils. (PubMed id 22015631)1 Neagoe P.E....Sirois M.G. (2012)
    776. Synergistic cooperation between methamphetamine and HI V-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes. (PubMed id 23251686)1 Shah A....Kumar A. (2012)
    777. Cigarette smoke and its component acrolein augment IL- 8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells. (PubMed id 22983351)1 Moretto N....Facchinetti F. (2012)
    778. Combined effects of CXCL8 and CXCR2 gene polymorphisms on susceptibility to systemic sclerosis. (PubMed id 22763041)1 Salim P.H....Xavier R.M. (2012)
    779. CD133(+) liver tumor-initiating cells promote tumor an giogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 sig naling. (PubMed id 21994122)1 Tang K.H....Chan K.W. (2012)
    780. Interleukin-8 secretion by ovarian cancer cells increa ses anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion. (PubMed id 22579115)1 Wang Y....Meng X.Y. (2012)
    781. The role of IL-8 in the SDF-1a/CXCR4-induced angiogene sis of laryngeal and hypopharyngeal squamous cell carcinoma. (PubMed id 22366438)1 Li K.C....Tan C.T. (2012)
    782. Correlation between maternal inflammatory markers and fetomaternal adiposity. (PubMed id 22726456)1 Farah N....Turner M.J. (2012)
    783. Synergism between interleukin (IL)-17 and Toll-like re ceptor 2 and 4 signals to induce IL-8 expression in cystic fibrosis airway epith elial cells. (PubMed id 22466961)1 Mizunoe S....Kai H. (2012)
    784. Toll-like receptor 9 mediates oral bacteria-induced IL -8 expression in gingival epithelial cells. (PubMed id 21968713)1 Kim Y....Choi Y. (2012)
    785. miRNA-146a expression positively regulates tumor necro sis factor-a-induced interleukin-8 production in mesenchymal stem cells and diff erentiated lung epithelial-like cells. (PubMed id 22876745)1 Perng D.W....Lee Y.C. (2012)
    786. HIV-1 matrix protein p17 promotes angiogenesis via che mokine receptors CXCR1 and CXCR2. (PubMed id 22904195)1 Caccuri F....Caruso A. (2012)
    787. Interleukin-8 derived from local tissue-resident strom al cells promotes tumor cell invasion. (PubMed id 21882260)1 Welte G....Song Y.H. (2012)
    788. A meta-analysis of interleukin-8 -251 promoter polymor phism associated with gastric cancer risk. (PubMed id 22279522)1 Xue H....Huang G. (2012)
    789. Synergistic interactions between chemokine receptor el ements in recognition of interleukin-8 by soluble receptor mimics. (PubMed id 22242662)1 Barter E.F. and Stone M.J. (2012)
    790. Interleukin-8, a promising predictor for prognosis of pancreatic cancer. (PubMed id 22416189)1 Chen Y....Zhu M.H. (2012)
    791. Regulation of interleukin-1alpha and tumor necrosis fa ctor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells. (PubMed id 22675954)1 Kawano Y....Narahara H. (2012)
    792. Excretory-secretory products of Giardia lamblia induce interleukin-8 production in human colonic cells via activation of p38, ERK1/2, NF-kB and AP-1. (PubMed id 22224945)1 Lee H.Y....Park S.J. (2012)
    793. Dental implants stimulate expression of Interleukin-8 and its receptor in human blood--an in vitro approach. (PubMed id 22454194)1 Quabius E.S....Kern M. (2012)
    794. Increase of toll-like receptor 4 but decrease of inter leukin-8 mRNA expression among ischemic stroke patients under aspirin treatment. (PubMed id 22580394)1 Wu D....Hu C.J. (2012)
    795. Toll-like receptor 1/2 stimulation induces elevated in terleukin-8 secretion in polymorphonuclear leukocytes isolated from preterm and term newborn infants. (PubMed id 21952587)1 Thornton N.L....Yost C.C. (2012)
    796. Seminal plasma induces angiogenic chemokine expression in cervical cancer cells and regulates vascular function. (PubMed id 22732298)1 Sales K.J....Katz A.A. (2012)
    797. Progressive increase of matrix metalloprotease-9 and i nterleukin-8 serum levels during carcinogenic process in human colorectal tract. (PubMed id 22848630)1 Biasi F....Poli G. (2012)
    798. Protein C activation peptide inhibits the expression o f ICAM-1, VCAM-1, and interleukin-8 induced by TNF-a in human dermal microvascul ar endothelial cells. (PubMed id 23042271)1 Pina-Canseco M.d.e.l. .S....Zenteno E. (2012)
    799. -251 T/A polymorphism of the interleukin-8 gene and ca ncer risk: a HuGE review and meta-analysis based on 42 case-control studies. (PubMed id 21681427)1 Wang N....Li Y. (2012)
    800. Haplotypes of susceptibility to chronic periodontitis in the Interleukin 8 gene do not influence protein level in the gingival crevicu lar fluid. (PubMed id 22877792)1 Corbi S.C....Scarel-Caminaga R.M. (2012)
    801. The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy. (PubMed id 22479352)1 Urbanek M....Lowe W.L. (2012)
    802. High baseline interleukine-8 level is an independent risk factor for the achievement of sustained virological response in chronic HC V patients. (PubMed id 21554996)1 Akbar H....Saleem S. (2011)
    803. Phosphorylation of the epidermal growth factor recept or (EGFR) is essential for interleukin-8 release from intestinal epithelial cel ls in response to challenge with Escherichia coli O157 : H7 flagellin. (PubMed id 21546588)1 Fraser-Pitt D.J....Smith D.G. (2011)
    804. Genetic variations in the interleukin-6 and interleuk in-8 genes and the interleukin-6 receptor gene in delirium. (PubMed id 21851175)1 van Munster Rooij S.E. (2011)
    805. SNAIL regulates interleukin-8 expression, stem cell-l ike activity, and tumorigenicity of human colorectal carcinoma cells. (PubMed id 21640118)1 Hwang W.L....Wang H.W. (2011)
    806. Licensing virus-specific T cells to secrete the neutr ophil attracting chemokine CXCL-8 during hepatitis B virus infection. (PubMed id 21876747)1 Gehring A.J....Bertoletti A. (2011)
    807. Role of CCR2 and IL-8 in acute lung injury: a new mec hanism and therapeutic target. (PubMed id 21348591)1 Shen Y....Wang X. (2011)
    808. Increased expression of S100 calcium binding protein A8 in GM-CSF-stimulated neutrophils leads to the increased expressions of IL-8 and IL-16. (PubMed id 21961943)1 Katano M....Kato T. (2011)
    809. Suppression of IL-8 production from airway cells by t iotropium bromide in vitro. (PubMed id 22003289)1 Suzaki I....Suzaki H. (2011)
    810. IL-8-251A>T polymorphism is associated with breast cancer risk: a meta-analysis. (PubMed id 21468699)1 Huang Q....Yu J.H. (2011)
    811. Hydrogen sulfide inhibits IL-8 expression in human ke ratinocytes via MAP kinase signaling. (PubMed id 21555999)1 Mirandola P....Vitale M. (2011)
    812. An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway. (PubMed id 21316925)1 Tsuji G....Furue M. (2011)
    813. The role of IL-6, IL-8 and MCP-1 and their promoter p olymorphisms IL-6 -174GC, IL-8 -251AT and MCP-1 -2518AG in the risk of venous t hromboembolism: a case-control study. (PubMed id 21620438)1 Matos M.F....Morelli V.M. (2011)
    814. Constitutive ERK activity induces downregulation of t ristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability i n melanoma cells. (PubMed id 21593445)1 Bourcier C....PagA"s G. (2011)
    815. Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8. (PubMed id 21649887)1 Carpagnano G.E....Foschino-Barbaro M.P. (2011)
    816. Prognostic significance of IL-8-STAT-3 pathway in ast rocytomas: correlation with IL-6, VEGF and microvessel morphometry. (PubMed id 21684758)1 Piperi C....Korkolopoulou P. (2011)
    817. Nebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosis. (PubMed id 21330456)1 Reeves E.P....McElvaney N.G. (2011)
    818. [Relationship between polymorphism of interleukin-8 an d silicosis susceptibility]. (PubMed id 22214159)1 Sun D....Li C.L. (2011)
    819. Steroid-insensitive ERK1/2 activity drives CXCL8 synt hesis and neutrophilia by airway smooth muscle. (PubMed id 21493783)1 Robins S....Rousseau S. (2011)
    820. Mycoplasma pneumoniae induces interleukin-8 productio n via the epidermal growth factor receptor pathway. (PubMed id 21831204)1 Arae K....Taguchi H. (2011)
    821. Interleukin-8 is associated with proliferation, migra tion, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer ce ll line models. (PubMed id 20648559)1 Ning Y....Lenz H.J. (2011)
    822. CXCL8 protects human neurons from amyloid-I^-induced n eurotoxicity: relevance to Alzheimer's disease. (PubMed id 21840299)1 Ashutosh ....Ghorpade A. (2011)
    823. The dual role of CXCL8 in human CNS stem cell function : multipotent neural stem cell death and oligodendrocyte progenitor cell chemota xis. (PubMed id 22407782)1 Kelland E.E....Lund B.T. (2011)
    824. Increases of vitreous monocyte chemotactic protein 1 a nd interleukin 8 levels in patients with concurrent hypertension and diabetic re tinopathy. (PubMed id 21610567)1 Wakabayashi Y....Goto H. (2011)
    825. miR-520b regulates migration of breast cancer cells b y targeting hepatitis B X-interacting protein and interleukin-8. (PubMed id 21343296)1 Hu N....Ye L. (2011)
    826. Effect of exposure conditions on SWCNT-induced inflam matory response in human alveolar epithelial cells. (PubMed id 21477645)1 Baktur R....Kwon S. (2011)
    827. A candidate gene study of the type I interferon pathw ay implicates IKBKE and IL8 as risk loci for SLE. (PubMed id 21179067)1 Sandling J.K....SyvAonen A.C. (2011)
    828. Down-regulation of cytokine-induced interleukin-8 req uires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosph atase 1-dependent and -independent mechanisms. (PubMed id 21454676)1 Dauletbaev N....Lands L.C. (2011)
    829. Induction of TLR-2 and TLR-5 expression by Helicobact er pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-I+. (PubMed id 21573018)1 Kumar Pachathundikandi S....Backert S. (2011)
    830. Increased levels of human neutrophil peptides 1, 2, a nd 3 in peritoneal fluid of patients with endometriosis: association with neutr ophils, T cells and IL-8. (PubMed id 21831449)1 Milewski A.8....Malejczyk J. (2011)
    831. [Effects of NF-kappaB on the expression of IL-8 in hum an bronchial epithelial cells induced by cigarette smoke condensates]. (PubMed id 22043704)1 Zhang Q....Wu W. (2011)
    832. Advanced glycation end products (AGEs) induce apoptos is via a novel pathway: involvement of Ca2+ mediated by interleukin-8 protein. (PubMed id 21862577)1 Mahali S....Manna S.K. (2011)
    833. Interleukin-8 is activated in patients with chronic l iver diseases and associated with hepatic macrophage accumulation in human live r fibrosis. (PubMed id 21731723)1 Zimmermann H.W....Tacke F. (2011)
    834. [Association of IL-8 gene polymorphisms with inflammat ory bowel disease in Chinese patients]. (PubMed id 22093783)1 Liang W.D....Bi Y.T. (2011)
    835. Association of IL8 -251A/T, IL12B -1188A/C and TNF-I+ -238A/G polymorphisms with Tourette syndrome in a family-based association stud y in a Chinese Han population. (PubMed id 21443923)1 Liu S....Ma X. (2011)
    836. Regulation of the p38 mitogen-activated protein kinas e and dual-specificity phosphatase 1 feedback loop modulates the induction of i nterleukin 6 and 8 in cells infected with coronavirus infectious bronchitis vir us. (PubMed id 21959016)1 Liao Y....Liu D.X. (2011)
    837. Enhanced Ca2+ entry due to Orai1 plasma membrane inser tion increases IL-8 secretion by cystic fibrosis airways. (PubMed id 21873556)1 Balghi H....Hanrahan J.W. (2011)
    838. Human CD4+ FOXP3+ regulatory T cells produce CXCL8 an d recruit neutrophils. (PubMed id 21268001)1 Himmel M.E....Levings M.K. (2011)
    839. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL- 15 levels are independently prognostic in primary myelofibrosis: a comprehensiv e cytokine profiling study. (PubMed id 21300928)1 Tefferi A....Pardanani A. (2011)
    840. Modulation of NK cell autocrine-induced eosinophil ch emotaxis by interleukin-15 and vitamin D(3): a possible NK-eosinophil crosstalk via IL-8 in the pathophysiology of allergic rhinitis. (PubMed id 21765616)1 El-Shazly A.E. and Lefebvre P.P. (2011)
    841. Phospholipase C-I^3 is a key modulator of IL-8 express ion in cystic fibrosis bronchial epithelial cells. (PubMed id 21411730)1 Bezzerri V....Cabrini G. (2011)
    842. NF-kB feedback control of JNK1 activation modulates TR PV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells . (PubMed id 22171160)1 Wang Z....Reinach P.S. (2011)
    843. Novel roles for hypoxia and prostaglandin E2 in the r egulation of IL-8 during endometrial repair. (PubMed id 21356375)1 Maybin J.A....Critchley H.O. (2011)
    844. Bronchial epithelial cells release IL-6, CXCL1 and CXC L8 upon mast cell interaction. (PubMed id 22030312)1 Cao J....Zhang L. (2011)
    845. Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxi dation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia c ell) cells. (PubMed id 21745629)1 Choi S.E....Lee K.W. (2011)
    846. Sulforaphane inhibits de novo synthesis of IL-8 and M CP-1 in human epithelial cells generated by cigarette smoke extract. (PubMed id 21401388)1 Starrett W. and Blake D.J. (2011)
    847. Elevated miR-155 promotes inflammation in cystic fibr osis by driving hyperexpression of interleukin-8. (PubMed id 21282106)1 Bhattacharyya S....Biswas R. (2011)
    848. Knockdown of CypA inhibits interleukin-8 (IL-8) and I L-8-mediated proliferation and tumor growth of glioblastoma cells through down- regulated NF-I_B. (PubMed id 20454998)1 Sun S....Chiu R. (2011)
    849. Control of cell migration and inflammatory mediators p roduction by CORM-2 in osteoarthritic synoviocytes. (PubMed id 21961038)1 Garcia-Arnandis I....Alcaraz M.J. (2011)
    850. Interactions of interleukin-8 with the human chemokin e receptor CXCR1 in phospholipid bilayers by NMR spectroscopy. (PubMed id 22019593)1 Park S.H....Opella S.J. (2011)
    851. Identification of a novel immunomodulatory gliadin pe ptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease. (PubMed id 21091908)1 Lammers K.M....Fasano A. (2011)
    852. Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme- dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H 292) cells. (PubMed id 21925169)1 Kim S....Nadel J.A. (2011)
    853. Interleukin-8 overexpression in astrocytomas is induc ed by prostaglandin E2 and is associated with the transcription factors CCAAT/e nhancer-binding protein-I^ and CCAAT/enhancer-binding homologous protein. (PubMed id 21471847)1 Venza M....Teti D. (2011)
    854. Thrombin induces NF-kappaB activation and IL-8/CXCL8 expression in lung epithelial cells by a Rac1-dependent PI3K/Akt pathway. (PubMed id 21266580)1 Lin C.H....Chen B.C. (2011)
    855. MAPK signaling pathways regulate IL-8 mRNA stability and IL-8 protein expression in cystic fibrosis lung epithelial cell lines. (PubMed id 20952496)1 Bhattacharyya S....Biswas R. (2011)
    856. ERI^ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. (PubMed id 21266854)1 Chen Y....Shao Z.M. (2011)
    857. Semaphorin 7A on keratinocytes induces interleukin-8 production by monocytes. (PubMed id 21524887)1 Kamata M....Sato S. (2011)
    858. P. aeruginosa drives CXCL8 synthesis via redundant to ll-like receptors and NADPH oxidase in CFTRa88F508 airway epithelial cells. (PubMed id 21176887)1 Roussel L....Rousseau S. (2011)
    859. Low molecular weight hyaluronan, via AP-1 and NF-kB si gnalling, induces IL-8 in transformed bronchial epithelial cells. (PubMed id 21989944)1 Ochoa C....Quinn D. (2011)
    860. Expression of pigment epithelium-derived factor in bla dder tumour is correlated with interleukin-8 yet not with interleukin-1a. (PubMed id 21336718)1 Feng C....Wu Z. (2011)
    861. Oct4-related cytokine effects regulate tumorigenic pr operties of colorectal cancer cells. (PubMed id 22037460)1 Chang C.J....Lan Y.T. (2011)
    862. Interaction of aryl hydrocarbon receptor and NF-I_B su bunit RelB in breast cancer is associated with interleukin-8 overexpression. (PubMed id 21640702)1 Vogel C.F....Matsumura F. (2011)
    863. Effects of 15-deoxy-a88A^A^,A^a8'-prostaglandin Ja88 on the pr oduction of IL-8 and the expression of Toll-like receptor 2 in human primary ke ratinocytes stimulated with lipopolysaccharide. (PubMed id 20174873)1 Kim Y.I....Lee H.K. (2011)
    864. PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor/phospholipase A2 and regulation of NFI_B and PPARI^. (PubMed id 21570865)1 Hirsch J....Filleur S. (2011)
    865. Molecular dynamics simulations of CXCL-8 and its inte ractions with a receptor peptide, heparin fragments, and sulfated linked cyclit ols. (PubMed id 21299226)1 Gandhi N.S. and Mancera R.L. (2011)
    866. The diagnostic value of CRP, IL-8, PCT, and sTREM-1 in the detection of bacterial infections in pediatric oncology patients with febri le neutropenia. (PubMed id 20803037)1 Miedema K.G....Tissing W.J. (2011)
    867. A promoter SNP rs4073T>A in the common allele of t he interleukin 8 gene is associated with the development of idiopathic pulmonar y fibrosis via the IL-8 protein enhancing mode. (PubMed id 21649933)1 Ahn M.H....Shim Y.S. (2011)
    868. Interleukin-8 induces the endothelial cell migration through the activation of phosphoinositide 3-kinase-Rac1/RhoA pathway. (PubMed id 21750647)1 Lai Y....Liu Y.F. (2011)
    869. Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma l evels of interleukin 8. (PubMed id 21046243)1 Shanab A.A....Quigley E.M. (2011)
    870. TGFB1 and IL8 gene polymorphisms and susceptibility t o visceral leishmaniasis. (PubMed id 21376140)1 Frade A.F....Goldberg A.C. (2011)
    871. Mast cell-derived TNF-a and histamine modify IL-6 and IL-8 expression and release from cutaneous tumor cells. (PubMed id 21995333)1 Artuc M....Zuberbier T. (2011)
    872. Serum TNF-I+, sTNFR1, IL-6, IL-8 and IL-10 levels in W eil's syndrome. (PubMed id 21316985)1 Kyriakidis I....Papa A. (2011)
    873. Lipopolysaccharide activated phosphatidylcholine-spec ific phospholipase C and induced IL-8 and MCP-1 production in vascular endothel ial cells. (PubMed id 21413027)1 Zhang L....Miao J.Y. (2011)
    874. Inhibited proliferation of human lung fibroblasts by LPS is through IL-6 and IL-8 release. (PubMed id 21419646)1 Zhang J....Qu J.M. (2011)
    875. The role of cytokines IL-6 and IL-8 in the pathogenes is of spontaneous abortions. (PubMed id 21591973)1 Galazios G....Liberis V. (2011)
    876. Chemokines plasma levels in preterm newborns of preec lamptic mothers. (PubMed id 21820916)1 Faulhaber F.R....Procianoy R.S. (2011)
    877. Pulmonary epithelial CCR3 promotes LPS-induced lung i nflammation by mediating release of IL-8. (PubMed id 21660963)1 Li B....Bai C. (2011)
    878. Hepatocyte growth factor and keratinocyte growth fact or enhance IL-1-induced IL-8 secretion through different mechanisms in Caco-2 e pithelial cells. (PubMed id 21082280)1 Unger B.L. and McGee D.W. (2011)
    879. Correlation of polymorphism of IL-8 and MMP-7 with occ urrence and lymph node metastasis of early stage cervical cancer. (PubMed id 21336735)1 Wu S....Xie J. (2011)
    880. NTPDase1 controls IL-8 production by human neutrophil s. (PubMed id 21670316)1 Kukulski F....SAcvigny J. (2011)
    881. Hepatitis B virus induces a novel inflammation networ k involving three inflammatory factors, IL-29, IL-8, and cyclooxygenase-2. (PubMed id 21957142)1 Yu Y....Wu J. (2011)
    882. Haplotypes in the interleukin 8 gene and their associ ation with chronic periodontitis susceptibility. (PubMed id 21188496)1 Scarel-Caminaga R.M....Cirelli J.A. (2011)
    883. Helicobacter pylori CagA-mediated IL-8 induction in ga stric epithelial cells is cholesterol-dependent and requires the C-terminal tyro sine phosphorylation-containing domain. (PubMed id 22092715)1 Lai C.H....Wang W.C. (2011)
    884. Polymorphisms in inflammatory response genes and their association with gastric cancer: A HuGE systematic review and meta-analyses. (PubMed id 21178102)4 Persson C....Forman D. (2011)
    885. [Influence of genetic mutations on clinical presentat ion of subretinal neovascularization. Report 1: The impact of CFH and IL-8 gene s polymorphism]. (PubMed id 21882633)1 Budzinskaia M.V....Galoian N.S. (2011)
    886. The IL-8-regulated chemokine receptor CXCR7 stimulate s EGFR signaling to promote prostate cancer growth. (PubMed id 21398406)1 Singh R.K. and Lokeshwar B.L. (2011)
    887. Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcrip tion. (PubMed id 20886283)1 Ritter B....Nourbakhsh M. (2011)
    888. CC and CXC chemokines induce airway smooth muscle pro liferation and survival. (PubMed id 21368236)1 Halwani R....Hamid Q. (2011)
    889. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    890. Interleukin(IL)-4 promotion of CXCL-8 gene transcript ion is mediated by ERK1/2 pathway in human pulmonary artery endothelial cells. (PubMed id 21645924)1 Yang D.F....Lavoie J.P. (2011)
    891. Suppression of zinc finger protein 580 by high oxLDL/ LDL-ratios is followed by enhanced expression of endothelial IL-8. (PubMed id 21310414)1 Hoffmann C.J....Zakrzewicz A. (2011)
    892. Plantaricin A synthesized by Lactobacillus plantarum induces in vitro proliferation and migration of human keratinocytes and increas es the expression of TGF-I^1, FGF7, VEGF-A and IL-8 genes. (PubMed id 21782870)1 Pinto D....De Angelis M. (2011)
    893. Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells. (PubMed id 21225224)1 Li Y.Y....Kinoshita Y. (2011)
    894. IL-8 increases integrin expression and cell motility in human chondrosarcoma cells. (PubMed id 21590707)1 Lee C.Y....Tang C.H. (2011)
    895. Determination of strains of Helicobacter pylori and o f polymorphism in the interleukin-8 gene in patients with stomach cancer. (PubMed id 21537542)1 Vinagre R.M....Martins L.C. (2011)
    896. Interleukin-8 gene promoter polymorphism (rs4073) may contribute to chronic periodontitis. (PubMed id 21091348)1 Andia Souza A.P. (2011)
    897. Increased interleukin (IL)-8 and decreased IL-17 produ ction in chronic obstructive pulmonary disease (COPD) provoked by cigarette smok e. (PubMed id 21996014)1 Zhang X....He S. (2011)
    898. Relationship of interleukin-8 gene polymorphisms with hepatocellular carcinoma susceptibility and pathological development. (PubMed id 21780129)1 Chien M.H....Kuo W.H. (2011)
    899. Plexin-B1 activates NF-kB and IL-8 to promote a pro-an giogenic response in endothelial cells. (PubMed id 22028792)1 Yang Y.H....Basile J.R. (2011)
    900. Hydrogen sulfide inhibits proliferation and release o f IL-8 from human airway smooth muscle cells. (PubMed id 21297080)1 Perry M.M....Chung K.F. (2011)
    901. The secret second life of an innocent chaperone: the story of CD74 and B cell/chronic lymphocytic leukemia cell survival. (PubMed id 21417823)1 Shachar I. and Haran M. (2011)
    902. Kaposi's sarcoma-associated herpesvirus-encoded laten cy-associated nuclear antigen reduces interleukin-8 expression in endothelial c ells and impairs neutrophil chemotaxis by degrading nuclear p65. (PubMed id 21697472)1 Li X....Lan K. (2011)
    903. Effects of chronic ascariasis and trichuriasis on cyt okine production and gene expression in human blood: a cross-sectional study. (PubMed id 21666788)1 Reina Ortiz M....Cooper P.J. (2011)
    904. NF-kB and CREB are involved in IL-8 production of huma n neutrophils induced by Trichomonas vaginalis-derived secretory products. (PubMed id 22072831)1 Nam Y.H....Shin M.H. (2011)
    905. Biological activity of CXCL8 forms generated by altern ative cleavage of the signal peptide or by aminopeptidase-mediated truncation. (PubMed id 21904597)1 Mortier A....Proost P. (2011)
    906. A new isoform of interleukin-32 suppresses IL-8 mRNA expression in the intestinal epithelial cell line HT-29. (PubMed id 21468596)1 Imaeda H....Fujiyama Y. (2011)
    907. Interleukin-8 gene polymorphism is associated with ac ute coronary syndrome in the Chinese Han population. (PubMed id 21763153)1 Zhang X....Yan C. (2011)
    908. Myeloid angiogenic cells act as alternative M2 macroph ages and modulate angiogenesis through interleukin-8. (PubMed id 21670847)1 Medina R.J....Stitt A.W. (2011)
    909. Urine IL-8 concentrations in infectious and non-infec tious urinary tract conditions. (PubMed id 21603907)1 Bitsori M....Galanakis E. (2011)
    910. IL-8 signaling plays a critical role in the epithelia l-mesenchymal transition of human carcinoma cells. (PubMed id 21653678)1 Fernando R.I....Palena C. (2011)
    911. CXCR1 and CXCR2 silencing modulates CXCL8-dependent en dothelial cell proliferation, migration and capillary-like structure formation. (PubMed id 21749879)1 Singh S....Singh R.K. (2011)
    912. Mycobacterium abscessus glycopeptidolipid prevents res piratory epithelial TLR2 signaling as measured by HbD2 gene expression and IL-8 release. (PubMed id 22216191)1 Davidson L.B....Byrd T.F. (2011)
    913. Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation. (PubMed id 21423807)1 Alfaro C....Melero I. (2011)
    914. The role of phagocytosis in IL-8 production by human monocytes in response to lipoproteins on Staphylococcus aureus. (PubMed id 21333631)1 Kang H.J....Lee B.L. (2011)
    915. Interleukin-17F increases the secretion of interleuki n-8 and the expression of cyclooxygenase 2 in endometriosis. (PubMed id 21601196)1 Hirata T....Taketani Y. (2011)
    916. CXCL8 and CCL5 expression in synovial fluid and blood serum in patients with osteoarthritis of the knee. (PubMed id 21336628)1 Pierzchala A.W....Hajduk G. (2011)
    917. Hypoxia induces cysteine-rich 61, vascular endothelia l growth factor, and interleukin-8 expressions in human nasal polyp fibroblasts : An implication of neutrophils in the pathogenesis of nasal polyposis. (PubMed id 21711965)1 Shun C.T....Liu C.M. (2011)
    918. Shigella enterotoxin-2 is a type III effector that pa rticipates in Shigella-induced interleukin 8 secretion by epithelial cells. (PubMed id 21219446)1 FarfA!n M.J....Nataro J.P. (2011)
    919. Prognostic significance of IL-6 and IL-8 ascites leve ls in ovarian cancer patients. (PubMed id 21619709)1 Lane D....PichAc A. (2011)
    920. Endothelial lipase (EL) and EL-generated lysophosphat idylcholines promote IL-8 expression in endothelial cells. (PubMed id 21130993)1 Riederer M....Frank S. (2011)
    921. Mid-trimester amniotic fluid concentrations of the pr oinflammatory cytokines IL-6, IL-8, TNF-I+, and lipopolysaccharide binding prote in in normal pregnancies: a prospective evaluation according to parity, gestati onal age, and fetal gender. (PubMed id 21702700)1 Bamberg C....Kalache K. (2011)
    922. Pulmonary proteases in the cystic fibrosis lung induc e interleukin 8 expression from bronchial epithelial cells via a heme/meprin/ep idermal growth factor receptor/Toll-like receptor pathway. (PubMed id 21193404)1 Cosgrove S....McElvaney N.G. (2011)
    923. TNF-alpha and IL-8: serum levels and gene polymorphis ms (-308G>A and -251A>T) are associated with classical biomarkers and med ical history in children with sickle cell anemia. (PubMed id 21802960)1 Cajado C....Goncalves M.S. (2011)
    924. Cytokine responses to carbohydrate ingestion during r ecovery from exercise-induced muscle injury. (PubMed id 20187772)1 Ross M.L....Peake J.M. (2010)
    925. Paget's disease of bone is not associated with common polymorphisms in interleukin-6, interleukin-8 and tumor necrosis factor alpha genes. (PubMed id 20709566)1 Corral-Gudino L....GonzA!lez-Sarmiento R. (2010)
    926. Adenosine modulates HIF-1{alpha}, VEGF, IL-8, and foa m cell formation in a human model of hypoxic foam cells. (PubMed id 19834107)1 Gessi S....Borea P.A. (2010)
    927. [Induction of IL-8 by Chlamydia trachomatis through M APK pathway rather than NF-kappaB pathway]. (PubMed id 20448351)1 Chen F....Yu P. (2010)
    928. Short-term IL-1beta blockade reduces monocyte CD11b i ntegrin expression in an IL-8 dependent fashion in patients with type 1 diabete s. (PubMed id 20483667)1 Sanda S....Greenbaum C. (2010)
    929. Involvement of capsular polysaccharide via a TLR2/NF- kappaB pathway in Vibrio vulnificus-induced IL-8 secretion of human intestinal epithelial cells. (PubMed id 20198307)1 Lee B.C....Kim T.S. (2010)
    930. [Expression of NF-kappaB and its downstream products in human umbilical vascular endothelial cells treated with paraquat]. (PubMed id 20506652)1 Yu H.F. and Nie H. (2010)
    931. Genetic Polymorphisms and Susceptibility to Parenchym al Renal Infection Among Pediatric Patients. (PubMed id 21042230)1 Cheng C.H....Lin T.Y. (2010)
    932. ROCK2 associates with lectin-like oxidized LDL recept or-1 and mediates oxidized LDL-induced IL-8 production. (PubMed id 20181930)1 Mattaliano M.D....Paulsen J.E. (2010)
    933. The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis. (PubMed id 20518825)1 Miyoshi T....Uchiyama T. (2010)
    934. Enrichment of Foxp3+ CD4 regulatory T cells in migrat ed T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. (PubMed id 21048114)1 Eikawa S....Nakayama E. (2010)
    935. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    936. Interleukin-8 mediates resistance to antiangiogenic a gent sunitinib in renal cell carcinoma. (PubMed id 20103651)1 Huang D....Teh B.T. (2010)
    937. Co-elevated expression of hepatocyte growth factor an d Interleukin-8 contributes to poor prognosis of patients with primary nasophar yngeal carcinoma. (PubMed id 19956874)1 Xie L.Q....Liang Y.J. (2010)
    938. Association of polymorphisms in proinflammatory cytok ine genes with the development of oral cancer in Southern Thailand. (PubMed id 20133197)4 Kietthubthew S....Au W.W. (2010)
    939. Mammalian target of rapamycin (mTOR) and S6 kinase do wn-regulate phospholipase D2 basal expression and function. (PubMed id 20410302)1 Tabatabaian F....Gomez-Cambronero J. (2010)
    940. Engagement of toll-like receptor 3 induces vascular e ndothelial growth factor and interleukin-8 in human rheumatoid synovial fibrobl asts. (PubMed id 21179282)1 Moon S.J....Park S.H. (2010)
    941. Amino acids stimulate Akt phosphorylation, and reduce IL-8 production and NF-I_B activity in HepG2 liver cells. (PubMed id 20512787)1 van Meijl L.E....Mensink R.P. (2010)
    942. Variants of ADAMTS1 modify the effectiveness of stati ns in reducing the risk of myocardial infarction. (PubMed id 21037509)1 Peters B.J....Maitland-van der Zee A.H. (2010)
    943. The clinical Pseudomonas fluorescens MFN1032 strain e xerts a cytotoxic effect on epithelial intestinal cells and induces Interleukin -8 via the AP-1 signaling pathway. (PubMed id 20698984)1 Madi A....Connil N. (2010)
    944. Candida albicans releases soluble factors that potent iate cytokine production by human cells through a protease-activated receptor 1 - and 2-independent pathway. (PubMed id 19858310)1 Cheng S.C....Netea M.G. (2010)
    945. Role of interleukin 8 in uterine natural killer cell regulation of extravillous trophoblast cell invasion. (PubMed id 20483454)1 De Oliveira L.G....Robson S.C. (2010)
    946. Standardized tape stripping prior to patch testing in duces upregulation of Hsp90, Hsp70, IL-33, TNF-I+ and IL-8/CXCL8 mRNA: new insig hts into the involvement of 'alarmins'. (PubMed id 20731692)1 Dickel H....Skrygan M. (2010)
    947. Oxidative stress enhances IL-8 and inhibits CCL20 pro duction from intestinal epithelial cells in response to bacterial flagellin. (PubMed id 20595617)1 Ivison S.M....Steiner T.S. (2010)
    948. A whole genome association study of mother-to-child t ransmission of HIV in Malawi. (PubMed id 20487506)1 Joubert B.R....Meshnick S.R. (2010)
    949. Effect of natural commensal-origin DNA on toll-like r eceptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier inte gritiy of polarized intestinal epithelial cells. (PubMed id 19714766)1 Ghadimi D....Schrezenmeir J. (2010)
    950. Lead contributes to arterial intimal hyperplasia thro ugh nuclear factor erythroid 2-related factor-mediated endothelial interleukin 8 synthesis and subsequent invasion of smooth muscle cells. (PubMed id 20595649)1 Zeller I....Bernhard D. (2010)
    951. Macrophage migration inhibitory factor contributes an giogenesis by up-regulating IL-8 and correlates with poor prognosis of patients with primary nasopharyngeal carcinoma. (PubMed id 20872800)1 Liao B....Li B. (2010)
    952. Umbilical cord blood concentrations of IL-6, IL-8, an d MMP-8 in pregnancy complicated by preterm premature rupture of the membranes and histological chorioamnionitis. (PubMed id 21196908)1 Andrys C....Kacerovsky M. (2010)
    953. Cigarette smoke induces CXCL8 production by human neu trophils via activation of TLR9 receptor. (PubMed id 19840968)1 Mortaz E....Folkerts G. (2010)
    954. Pro-inflammatory interleukins in patients operated on for proximal femur fracture. (PubMed id 20218918)1 Kazmi S.S....rgensen J.J. (2010)
    955. Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocy te chemotactic protein-1 and nitric oxide are major regulatory factors. (PubMed id 20102417)1 Kumar R....Salotra P. (2010)
    956. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiat ion in rectal cancer. (PubMed id 20644561)1 Ho-Pun-Cheung A....Lopez-Crapez E. (2010)
    957. Integrin-mediated inhibition of interleukin-8 secreti on from human neutrophils by collagen type I. (PubMed id 19995941)1 Quan W.Y....Nishida T. (2010)
    958. TGFI^1 induces IL-6 and inhibits IL-8 release in human bronchial epithelial cells: the role of Smad2/3. (PubMed id 20607798)1 Ge Q....Burgess J.K. (2010)
    959. Cleavage of the NF-{kappa}B family protein p65/RelA b y the chlamydial protease-like activity factor (CPAF) impairs proinflammatory s ignaling in cells infected with Chlamydiae. (PubMed id 21041296)1 Christian J....HAocker G. (2010)
    960. Gene-gene interaction between tuberculosis candidate genes in a South African population. (PubMed id 20799037)1 de Wit E....Hoal E.G. (2010)
    961. Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors. (PubMed id 20630874)1 Joseph P.R....Rajarathnam K. (2010)
    962. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    963. Stretch and inflammation-induced Pre-B cell colony-en hancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells. (PubMed id 20598369)1 Kendal-Wright C.E....Bryant-Greenwood G.D. (2010)
    964. [Expressions of LL-37 and IL-8 in chronic sinusitis w ith nasal polyps]. (PubMed id 20556966)1 Xie D....Xie D. (2010)
    965. [Expression of IL-8, SP-A and TGF-beta1 in bronchoalv eolar lavage fluid of neonates with bronchopulmonary dysplasia]. (PubMed id 20540853)1 Liu D.Y....Feng Z.C. (2010)
    966. A20 is an early responding negative regulator of Toll -like receptor 5 signalling in intestinal epithelial cells during inflammation. (PubMed id 19912257)1 Oshima N....Kinoshita Y. (2010)
    967. Polymorphisms in the platelet-specific collagen recep tor GP6 are associated with risk of nonfatal myocardial infarction in Caucasian s. (PubMed id 20227257)1 Shaffer J.R....Donahue R.P. (2010)
    968. The -251A>T polymorphism of interleukin-8 is assoc iated with longer mechanical ventilation and hospital staying after coronary su rgery. (PubMed id 20206550)1 Wang Z....Wei M. (2010)
    969. Induction of interleukin-8 from nasal epithelial cell s during bacterial infection: the role of IL-8 for neutrophil recruitment in ch ronic rhinosinusitis. (PubMed id 20634942)1 Yoon B.N....Roh H.J. (2010)
    970. Role of inflammatory cells, cytokines and matrix meta lloproteinases in neutrophil-mediated skin diseases. (PubMed id 20636397)1 Marzano A.V....Crosti C. (2010)
    971. Cell-bound IL-8 increases in bronchial epithelial cel ls after arylsulfatase B silencing due to sequestration with chondroitin-4-sulf ate. (PubMed id 19346317)1 Bhattacharyya S....Tobacman J.K. (2010)
    972. Pneumococcal proteins PspA and PspC induce CXCL8 prod uction in human neutrophils: implications in pneumococcal infections. (PubMed id 20670689)1 Cao J....Zhang X. (2010)
    973. Phospholipase D signaling pathway is involved in lung cancer-derived IL-8 increased osteoclastogenesis. (PubMed id 20106902)1 Hsu Y.L....Kuo P.L. (2010)
    974. Differential transcriptional regulation of IL-8 expre ssion by human airway epithelial cells exposed to diesel exhaust particles. (PubMed id 19914270)1 Tal T.L....Samet J.M. (2010)
    975. Prenatal maternal stress and cord blood innate and ad aptive cytokine responses in an inner-city cohort. (PubMed id 20194818)1 Wright R.J....Gern J.E. (2010)
    976. IL8 and CXCL13 are potent chemokines for the recruitm ent of human neural precursor cells across brain endothelial cells. (PubMed id 20400187)1 Weiss N....Cazaubon S. (2010)
    977. [Relationship between serum IL-8 hsCRP, TNF-I+ and cor onary lesions in CHD patients]. (PubMed id 21033124)1 Luo J.G. (2010)
    978. LTDa88 induces HB-EGF-dependent CXCL8 release through E GFR activation in human bronchial epithelial cells. (PubMed id 20889674)1 McGovern T....Martin J.G. (2010)
    979. Systemic cytokine response in patients with community -acquired pneumonia. (PubMed id 20884746)1 Endeman H....Biesma D.H. (2010)
    980. Differential effects of human neutrophil peptide-1 on growth factor and interleukin-8 production by human lung fibroblasts and epith elial cells. (PubMed id 20715983)1 Amenomori M....Kohno S. (2010)
    981. LPS-induced IL-8 activation in human intestinal epith elial cells is accompanied by specific histone H3 acetylation and methylation c hanges. (PubMed id 20546607)1 Angrisano T....Lembo F. (2010)
    982. Respiratory echovirus 30 and coxsackievirus B5 can in duce production of RANTES, MCP-1 and IL-8 by human bronchial epithelial cells. (PubMed id 20540976)1 Renois F....AndrAcoletti L. (2010)
    983. Tumor cell extravasation mediated by leukocyte adhesi on is shear rate dependent on IL-8 signaling. (PubMed id 20379392)1 Liang S....Dong C. (2010)
    984. Role of chemokines in CNS health and pathology: a foc us on the CCL2/CCR2 and CXCL8/CXCR2 networks. (PubMed id 19904283)1 Semple B.D....Morganti-Kossmann M.C. (2010)
    985. [Overexpression of IL-8 and MMP-9 confer high maligna nt phenotype in patients with non-small cell lung cancer]. (PubMed id 20704821)1 Liu Z....Li F. (2010)
    986. Opisthorchis viverrini excretory/secretory products i nduce toll-like receptor 4 upregulation and production of interleukin 6 and 8 i n cholangiocyte. (PubMed id 20887801)1 Ninlawan K....Sripa B. (2010)
    987. Ketamine inhibits transcription factors activator pro tein 1 and nuclear factor-kappaB, interleukin-8 production, as well as CD11b an d CD16 expression: studies in human leukocytes and leukocytic cell lines. (PubMed id 20185670)1 Welters I.D....Goumon Y. (2010)
    988. Vitreous levels of VEGF, IL-8, and TNF-alpha in retin al detachment. (PubMed id 20465445)1 Rasier R....Bahcecioglu H. (2010)
    989. The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells. (PubMed id 19838218)1 Thobe M.N....Waltz S.E. (2010)
    990. Pneumocystis cell wall beta-glucan stimulates calcium -dependent signaling of IL-8 secretion by human airway epithelial cells. (PubMed id 20626862)1 Carmona E.M....Limper A.H. (2010)
    991. IL-8, IL-12 and IL-10 cytokines generation by neutrop hils, fibroblasts and neutrophils- fibroblasts interaction in psoriasis. (PubMed id 20934961)1 Glowacka E....Zalewska A. (2010)
    992. Selective upregulation of interleukin-8 by human rhab domyosarcomas in response to hypoxia: therapeutic implications. (PubMed id 19588509)1 Wysoczynski M....Ratajczak M.Z. (2010)
    993. I+-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8. (PubMed id 21060150)1 Bergin D.A....McElvaney N.G. (2010)
    994. The CXC chemokine-degrading protease SpyCep of Strept ococcus pyogenes promotes its uptake into endothelial cells. (PubMed id 20562101)1 Kaur S.J....Talay S.R. (2010)
    995. Gingko biloba extract reduces VEGF and CXCL-8/IL-8 le vels in keratinocytes with cumulative effect with epigallocatechin-3-gallate. (PubMed id 19597830)1 Trompezinski S....Viac J. (2010)
    996. Immunological parameters, including CXCL8 (IL-8) char acterize cerebro- and cardiovascular events in patients with peripheral artery diseases. (PubMed id 20384872)1 Szomjak E....Szodoray P. (2010)
    997. Stress effects on FosB- and interleukin-8 (IL8)-drive n ovarian cancer growth and metastasis. (PubMed id 20826776)1 Shahzad M.M....Sood A.K. (2010)
    998. Involvement of p120 in LPS-induced NF-kappaB activati on and IL-8 production in human bronchial epithelial cells. (PubMed id 20172018)1 Wang M....Wu R. (2010)
    999. The human ovarian follicular fluid level of interleuk in-8 is associated with follicular size and patient age. (PubMed id 19285667)1 Malizia B.A....Usheva A. (2010)
    1000. High cerebrospinal fluid antioxidants and interleukin 8 are protective of hypoxic brain damage in newborns. (PubMed id 20166885)1 Hussein M.H....Togari H. (2010)
    1001. Disulfide trapping of protein complexes on the yeast s urface. (PubMed id 20047188)1 Lim K.H....Park S. (2010)
    1002. HIV-1 infection inhibits cytokine production in human thymic macrophages. (PubMed id 20817073)1 Rozmyslowicz T....Gaulton G.N. (2010)
    1003. Bacteria-derived hydrogen sulfide promotes IL-8 produ ction from epithelial cells. (PubMed id 19932683)1 Chen W....Kawai T. (2010)
    1004. Serum eosinophil cationic protein and 27 cytokines/ch emokines in acute exacerbation of childhood asthma. (PubMed id 20523065)1 Kato M....Hayashi Y. (2010)
    1005. Serum interleukin-8 and insulin like growth factor-1 in Egyptian bladder cancer patients. (PubMed id 20571236)1 Mahmoud M.A....Elhadidy G.S. (2010)
    1006. Transient receptor potential melastatin 2 is required for lipopolysaccharide-induced cytokine production in human monocytes. (PubMed id 20107186)1 Wehrhahn J....Hauschildt S. (2010)
    1007. HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-I_B pathway and can be silenced by gp120- specific siRNA. (PubMed id 21190575)1 Shah A. and Kumar A. (2010)
    1008. Thromboxane A(2) increases endothelial permeability t hrough upregulation of interleukin-8. (PubMed id 20510674)1 Kim S.R....Bae M.K. (2010)
    1009. Peroxisome proliferator-activated receptor {delta} ac tivators induce IL-8 expression in nonstimulated endothelial cells in a transcr iptional and posttranscriptional manner. (PubMed id 20592029)1 Meissner M....Kaufmann R. (2010)
    1010. Regulation of IL-8 production by complement-activated product, C5a, in vitro and in vivo during sepsis. (PubMed id 20591742)1 Wang L....Li Y. (2010)
    1011. HIF-1alpha mediates the induction of IL-8 and VEGF ex pression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-l ike behaviour. (PubMed id 20039880)1 Cane G....Vouret-Craviari V. (2010)
    1012. Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer. (PubMed id 20711410)1 Gannon P.O....Mes-Masson A.M. (2010)
    1013. Induction of IL-6 and IL-8 by house dust mite allerge n Der p1 in cultured human nasal epithelial cells is associated with PAR/PI3K/N FkappaB signaling. (PubMed id 20733339)1 Shi J....Li H. (2010)
    1014. Positive transcription elongation factor b (P-TEFb) c ontributes to dengue virus-stimulated induction of interleukin-8 (IL-8). (PubMed id 20618343)1 Li L.L....Ping Y.H. (2010)
    1015. Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-alpha in normal pregnancies and in pregnancies complicated by preeclampsia. (PubMed id 20441409)1 Tosun M....MalatyalioA9lu E. (2010)
    1016. 17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor. (PubMed id 20378727)1 Chotirmall S.H....McElvaney N.G. (2010)
    1017. Endoplasmic reticulum stress-activated C/EBP homologo us protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma. (PubMed id 20829347)2 Park S.H....Moon Y. (2010)
    1018. Urinary levels of interleukin-6 and interleukin-8 in patients with vesicoureteral reflux and renal parenchymal scar. (PubMed id 20084405)1 Gokce I....Topuzoglu A. (2010)
    1019. Anthrax lethal toxin impairs IL-8 expression in epith elial cells through inhibition of histone H3 modification. (PubMed id 19343203)1 Raymond B....Touqui L. (2009)
    1020. Tumor necrosis factor (TNF)-alpha-induced IL-8 expression in gastric epithelial cells: role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1. (PubMed id 19376732)1 O'Hara A.M....Crowe S.E. (2009)
    1021. Interstitial concentrations of adipokines in subcutan eous abdominal and femoral adipose tissue. (PubMed id 19376162)1 Nielsen N.B....Stallknecht B. (2009)
    1022. Role of Tat protein in HIV neuropathogenesis. (PubMed id 19526283)1 Li W....Nath A. (2009)
    1023. Dynamic regulation of CXCR1 and CXCR2 homo- and heter odimers. (PubMed id 19890050)1 MartA-nez MuA+oz L....Mellado M. (2009)
    1024. Prostaglandin F(2alpha)-induced interleukin-8 production in human dental pulp cells is associated with MEK/ERK signaling. (PubMed id 19345795)1 Chang M.C....Jeng J.H. (2009)
    1025. Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts. (PubMed id 19013427)1 Kitahara K....Kawai S. (2009)
    1026. Regulation of chemokine production via oxidative path way in HeLa cells. (PubMed id 20150959)1 Kina S....Sunakawa H. (2009)
    1027. Nitroxide radical TEMPO reduces ozone-induced chemoki ne IL-8 production in lung epithelial cells. (PubMed id 19162161)1 Castagna R....Valacchi G. (2009)
    1028. Serum tumour necrosis factor-alpha and interleukin-8 levels in acromegalic patients: acromegaly may be associated with moderate infl ammation. (PubMed id 18673463)1 Arikan S....Gokalp D. (2009)
    1029. Identification of biologically active peptides that inhibit binding of human CXCL8 to its receptors from a random phage-epitope library. (PubMed id 19118103)1 Houimel M. and Mazzucchelli L. (2009)
    1030. Evaluation of plasma interleukin-8 concentration in p atients with prostate cancer and benign prostate hyperplasia. (PubMed id 19561378)1 Dehghani M....Shakeri S. (2009)
    1031. Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells. (PubMed id 18657231)1 Smadja D.M....Gaussem P. (2009)
    1032. Prostaglandin F(2alpha)-F-prostanoid receptor regulat es CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcine urin-NFAT pathway. (PubMed id 19819266)1 Sales K.J....Jabbour H.N. (2009)
    1033. Sterile trauma to normal human dermis invariably indu ces IL1beta, IL6 and IL8 in an innate response to 'danger'. (PubMed id 19734969)1 SjAPgren F. and Anderson C. (2009)
    1034. Angiotensin type 1 receptor expression and interleuki n-8 production in polymorphonuclear leukocytes of patients with peripheral arte rial disease. (PubMed id 19755917)1 Marino F....Cosentino M. (2009)
    1035. Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways. (PubMed id 19726162)1 Grange P.A....Dupin N. (2009)
    1036. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. (PubMed id 19176759)1 Hao Q....Tang H. (2009)
    1037. Physiologic cold shock increases adherence of Moraxel la catarrhalis to and secretion of interleukin 8 in human upper respiratory tra ct epithelial cells. (PubMed id 19835476)1 Spaniol V....Aebi C. (2009)
    1038. HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr). (PubMed id 19275586)1 Majumder B....Ayyavoo V. (2009)
    1039. Cellular interaction regulates interleukin-8 secretion by granulosa-lutein cells and monocytes/macrophages. (PubMed id 19086996)1 PoA8eA8 A....FedorcsA!k P. (2009)
    1040. Difference in the regulation of IL-8 expression induc ed by uropathogenic E. coli between two kinds of urinary tract epithelial cells . (PubMed id 19799797)1 Tsai K.W....Chen C.N. (2009)
    1041. Neurotensin signaling induces intracellular alkaliniz ation and interleukin-8 expression in human pancreatic cancer cells. (PubMed id 19393580)1 Olszewski U. and Hamilton G. (2009)
    1042. Induced interleukin-8 expression in gliomas by tumor- associated macrophages. (PubMed id 19156359)1 Hong T.M....Tsai J.C. (2009)
    1043. Human intestinal intraepithelial lymphocytes and epithelial cells coinduce interleukin-8 production through the CD2-CD58 interaction. (PubMed id 19109405)1 Ebert E.C....Praveen R. (2009)
    1044. Airway inflammation and upregulation of beta2 Mac-1 i ntegrin expression on circulating leukocytes of female ragpickers in India. (PubMed id 19372628)1 Ray M.R....Lahiri T. (2009)
    1045. Extracellular ATP and P2 receptors are required for I L-8 to induce neutrophil migration. (PubMed id 19303321)1 Kukulski F....SAcvigny J. (2009)
    1046. Clearance of apoptotic neutrophils is diminished in c ord blood monocytes and does not lead to reduced IL-8 production. (PubMed id 19668110)1 Gille C....Orlikowsky T.W. (2009)
    1047. Implications of Nef: host cell interactions in viral p ersistence and progression to AIDS. (PubMed id 20012528)1 Arhel N.J. and Kirchhoff F. (2009)
    1048. Increase of inflammatory markers after indoor renovat ion activities: the LISA birth cohort study. (PubMed id 19496969)1 Herberth G....Lehmann I. (2009)
    1049. Mechanical stretch enhances IL-8 production in pulmon ary microvascular endothelial cells. (PubMed id 19747898)1 Iwaki M....Hasegawa Y. (2009)
    1050. Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. (PubMed id 19141999)4 Giedraitis V....Glaser A. (2009)
    1051. The UDP-glucose receptor P2RY14 triggers innate mucos al immunity in the female reproductive tract by inducing IL-8. (PubMed id 19454705)1 Arase T....Maruyama T. (2009)
    1052. Circulating IL-8 levels in heart failure patients wit h and without metabolic syndrome. (PubMed id 19410569)1 Shin M.J....Kang S.M. (2009)
    1053. Pseudomonas aeruginosa induces interleukin-8 (IL-8) gene expression in human conjunctiva through the recruitment of both RelA and CCAAT/enhancer-binding protein beta to the IL-8 promoter. (PubMed id 19064995)1 Venza I....Teti D. (2009)
    1054. Leptin enhances synthesis of proinflammatory mediator s in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2 , IL-6, and IL-8 production. (PubMed id 19688109)1 Vuolteenaho K....Moilanen E. (2009)
    1055. Peripheral cytokines profile in Parkinson's disease. (PubMed id 18678243)1 Reale M....Onofrj M. (2009)
    1056. CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. (PubMed id 19112107)1 Martin D....Gutkind J.S. (2009)
    1057. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. (PubMed id 19170075)1 Mizutani K....Pienta K.J. (2009)
    1058. Cytokines derived from cultured skeletal muscle cells after mechanical strain promote neutrophil chemotaxis in vitro. (PubMed id 18974369)1 Peterson J.M. and Pizza F.X. (2009)
    1059. Sevoflurane and isoflurane decrease TNF-alpha-induced gene expression in human monocytic THP-1 cells: potential role of intracellular IkappaBalpha regulation. (PubMed id 19360326)1 Boost K.A....Zwissler B. (2009)
    1060. Tumor-derived CCL-2 and CXCL-8 as possible prognostic markers of breast cancer: correlation with estrogen and progestrone receptor p henotyping. (PubMed id 22059352)1 Ghoneim H.M....Demian S.R. (2009)
    1061. Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans. (PubMed id 19053024)1 Staiger H....HAoring H.U. (2009)
    1062. Structure-function relationship of Vpr: biological imp lications. (PubMed id 19275588)1 Morellet N....Bouaziz S. (2009)
    1063. Relaxin stimulates interleukin-6 and interleukin-8 se cretion from the extraplacental chorionic cytotrophoblast. (PubMed id 19467703)1 Bryant-Greenwood G.D....Novy M.J. (2009)
    1064. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    1065. MicroRNA 132 regulates nutritional stress-induced che mokine production through repression of SirT1. (PubMed id 19819989)1 Strum J.C....Waters K.M. (2009)
    1066. Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. (PubMed id 19359602)1 Yuan L....Oettgen P. (2009)
    1067. Differential activation and regulation of CXCR1 and C XCR2 by CXCL8 monomer and dimer. (PubMed id 19667085)1 Nasser M.W....Richardson R.M. (2009)
    1068. [Combined effect of high mobile group box-1 protein a nd lipopolysaccharide on release of cytokines from human HepG2 cells]. (PubMed id 19751561)1 Liu Z.F....Su L. (2009)
    1069. Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabete s mellitus. (PubMed id 19773182)1 Van Sickle B.J....Spagnoli A. (2009)
    1070. Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors. (PubMed id 18800145)1 Negaard H.F....Iversen P.O. (2009)
    1071. The 15(S)-hydroxyeicosatetraenoic acid-induced angiog enesis requires Janus kinase 2-signal transducer and activator of transcription -5B-dependent expression of interleukin-8. (PubMed id 19349617)1 Cheranov S.Y....Rao G.N. (2009)
    1072. Serum interleukin-6 and interleukin-8 are early bioma rkers of acute kidney injury and predict prolonged mechanical ventilation in ch ildren undergoing cardiac surgery: a case-control study. (PubMed id 19570208)1 Liu K.D....Faubel S. (2009)
    1073. Cellular senescence and inflammation: a noteworthy li nk. (PubMed id 19325234)1 Tsirpanlis G. (2009)
    1074. IL-8 regulates mucin gene expression at the posttrans criptional level in lung epithelial cells. (PubMed id 19596978)1 Bautista M.V....Rose M.C. (2009)
    1075. HIF-1 induction attenuates Nrf2-dependent IL-8 expres sion in human endothelial cells. (PubMed id 19254160)1 Loboda A....Dulak J. (2009)
    1076. Proinflammatory tissue response and recovery of adipo kines during 4 days of subcutaneous large-pore microdialysis. (PubMed id 19328242)1 Clausen T.S....Stallknecht B. (2009)
    1077. Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. (PubMed id 19805069)1 Orjalo A.V....Campisi J. (2009)
    1078. Concentrated ambient ultrafine particle exposure indu ces cardiac changes in young healthy volunteers. (PubMed id 19234105)1 Samet J.M....Devlin R.B. (2009)
    1079. The IL-8 production by Streptococcal pyrogenic exotox in B. (PubMed id 19855073)1 Chang C.W....Lin M.T. (2009)
    1080. Modulation of expression of IL-8 gene in bronchial ep ithelial cells by 5-methoxypsoralen. (PubMed id 19720161)1 Nicolis E....Cabrini G. (2009)
    1081. CHFR, a potential tumor suppressor, downregulates int erleukin-8 through the inhibition of NF-kappaB. (PubMed id 19448676)1 Kashima L....Tokino T. (2009)
    1082. Interleukin 8 and cardiovascular disease. (PubMed id 19617600)1 Apostolakis S....Spandidos D.A. (2009)
    1083. CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. (PubMed id 19035451)1 Matsuo Y....Guha S. (2009)
    1084. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (2009)
    1085. Enterohemorrhagic Escherichia coli suppresses inflamm atory response to cytokines and its own toxin. (PubMed id 19556613)1 Bellmeyer A....Hecht G. (2009)
    1086. Molecular requirements for sorting of the chemokine i nterleukin-8/CXCL8 to endothelial Weibel-Palade bodies. (PubMed id 19578117)1 Hol J....OynebrAYten I. (2009)
    1087. Monocyte chemoattractant protein-1 plays a dominant r ole in the chronic inflammation observed in Alzheimer's disease. (PubMed id 18637012)1 Sokolova A....Shepherd C.E. (2009)
    1088. Developmental changes in circulating IL-8/CXCL8 isofo rms in neonates. (PubMed id 19232500)1 Maheshwari A....Ohls R.K. (2009)
    1089. Identification of candidate genes for susceptibility to reactive arthritis. (PubMed id 19506876)1 Rihl M....Kuipers J.G. (2009)
    1090. Inhibitory effects of flavonoids on TNF-alpha-induced IL-8 gene expression in HEK 293 cells. (PubMed id 19470239)1 Lee S....Kwon H.J. (2009)
    1091. Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model. (PubMed id 19021203)1 Schauer I.G....Rowley D.R. (2009)
    1092. Epicatechin suppresses IL-6, IL-8 and enhances IL-10 production with NF-kappaB nuclear translocation in whole blood stimulated syste m. (PubMed id 19300393)1 Al-Hanbali M....Matalka K.Z. (2009)
    1093. Structural basis for differential binding of the inte rleukin-8 monomer and dimer to the CXCR1 N-domain: role of coupled interactions and dynamics. (PubMed id 19681642)1 Ravindran A....Rajarathnam K. (2009)
    1094. The angiogenic effect of probiotic Bacillus polyferme nticus on human intestinal microvascular endothelial cells is mediated by IL-8. (PubMed id 20501448)1 Im E....Rhee S.H. (2009)
    1095. Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function. (PubMed id 19339032)1 Cochrane A....Frappier L. (2009)
    1096. The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ. (PubMed id 18850010)1 GAPransson M....Aman P. (2009)
    1097. Elevated tear interleukin-6 and interleukin-8 levels in patients with conjunctivochalasis. (PubMed id 19158563)1 Erdogan-Poyraz C....Orhan M. (2009)
    1098. Hepatocyte growth factor induces hypoxia-related inte rleukin-8 expression in lung adenocarcinoma cells. (PubMed id 19184985)1 Chiang Y.Y. (2009)
    1099. Human carotid plaque calcification and vulnerability. Relationship between degree of plaque calcification, fibrous cap inflammatory gene expression and symptomatology. (PubMed id 19136823)1 Wahlgren C.M....Bassiouny H.S. (2009)
    1100. Inflammation at birth is associated with subnormal development in very preterm infants. (PubMed id 18391842)1 Hansen-Pupp I....Ley D. (2008)
    1101. Interleukin-8 production from human umbilical vein endothelial cells during brief hyperglycemia: the effect of tumor necrotic factor-alpha. (PubMed id 17707405)1 Kinoshita K....Moriya T. (2008)
    1102. Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction. (PubMed id 18644894)1 Nakao S....Takeichi M. (2008)
    1103. Identification of patients with chronic obstructive p ulmonary disease (COPD) by measurement of plasma biomarkers. (PubMed id 20298300)1 Shaker S.B....Dirksen A. (2008)
    1104. Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function. (PubMed id 18536738)1 Sorrentino R....Mitchell J.A. (2008)
    1105. AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva. (PubMed id 18650551)1 Palanisamy V....Wong D.T. (2008)
    1106. Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kappaB and JNK/AP-1 pathways. (PubMed id 18322253)1 Scupoli M.T....Pizzolo G. (2008)
    1107. Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling. (PubMed id 18283335)1 Warner K.A....Nor J.E. (2008)
    1108. Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization. (PubMed id 18249366)1 Morelli S.S....Noyes N. (2008)
    1109. [Effects of secretory leukocyte protease inhibitor on expression of inflammation mediators in normal human bronchial epithelial cell s induced by cigarette smoke extract] (PubMed id 18953959)1 Qu M.Y....Gu Q.H. (2008)
    1110. CD40-CD40 ligand interactions in human microglia induc e CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1 /2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator p rotein-1 (AP-1). (PubMed id 17918746)1 D'Aversa T.G....Berman J.W. (2008)
    1111. Campylobacter jejuni invade chicken LMH cells inefficiently and stimulate differential expression of the chicken CXCLi1 and CXCLi2 cytokines. (PubMed id 19047751)1 Larson C.L....Konkel M.E. (2008)
    1112. Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism. (PubMed id 18424663)1 Burke S.M....Marshall J.S. (2008)
    1113. The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription. (PubMed id 18226242)1 Vardabasso C.... Giacca M. (2008)
    1114. The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils. (PubMed id 19086264)1 Chakrabarti S. and Patel K.D. (2008)
    1115. Live and ultraviolet-inactivated Lactobacillus rhamnosus GG decrease flagellin-induced interleukin-8 production in Caco-2 cells. (PubMed id 18936229)1 Lopez M....Neu J. (2008)
    1116. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (2008)
    1117. Urinary interleukin-8 in acute pyelonephritis of chil dren: a before-after study. (PubMed id 19377236)1 Mohkam M....Abdollah Gorgi F. (2008)
    1118. Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements. (PubMed id 18691435)1 Jiang W....Yang B. (2008)
    1119. Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. (PubMed id 18086816)1 Cheng W....Zhong G. (2008)
    1120. IFN-beta-mediated inhibition of IL-8 expression requires the ISGF3 components Stat1, Stat2, and IRF-9. (PubMed id 18370868)1 Laver T....Benveniste E.N. (2008)
    1121. Tight junction regulation by morphine and HIV-1 tat mo dulates blood-brain barrier permeability. (PubMed id 18574677)1 Mahajan S.D....Schwartz S.A. (2008)
    1122. The role of portal vein clamping for cytokine release and neutrophils activity during liver resection and transplant. (PubMed id 19338485)1 Studzinski A....Juettner B. (2008)
    1123. Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms. (PubMed id 18184679)1 Slevogt H....N'Guessan P.D. (2008)
    1124. Necrotic foci, elevated chemokines and infiltrating neutrophils in the liver of glycogen storage disease type Ia. (PubMed id 18191274)1 Kim S.Y....Chou J.Y. (2008)
    1125. Lactobacilli inhibit interleukin-8 production induced by Helicobacter pylori lipopolysaccharide-activated Toll-like receptor 4. (PubMed id 18763295)1 Zhou C....Ma H.S. (2008)
    1126. CD36 is significantly correlated with adipophilin in human carotid lesions and inversely correlated with plasma ApoAI. (PubMed id 18827892)1 Collot-Teixeira S....McGregor J.L. (2008)
    1127. Reactive oxygen species and chemokines: are they elevated in the esophageal mucosa of children with gastroesophageal reflux disease? (PubMed id 18506929)1 Tutar E....Pehlivanoglu E. (2008)
    1128. IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. (PubMed id 18566434)1 Skov L....van de Winkel J.G. (2008)
    1129. Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. (PubMed id 18258920)1 Bezzerri V....Cabrini G. (2008)
    1130. Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis. (PubMed id 18662984)1 Sai J....Richmond A. (2008)
    1131. Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. (PubMed id 18467491)1 Wu K....Pestell R.G. (2008)
    1132. Source of inflammatory markers in patients with atrial fibrillation. (PubMed id 18523031)1 Liuba I....Walfridsson H. (2008)
    1133. Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events. (PubMed id 18469140)1 Gouwy M....Van Damme J. (2008)
    1134. Immune mediators in idiopathic nephrotic syndrome: evidence for a relation between interleukin 8 and proteinuria. (PubMed id 18679168)1 Souto M.F....SimA/es E Silva A.C. (2008)
    1135. [Effect of Zn2+ on level of IL-8 and TNF-alpha mRNA a nd protein expressed of human II alveolar epithelial cells] (PubMed id 18646527)1 Zhang Q....Shi S. (2008)
    1136. Relationships between Helicobacter pylori infection status, endoscopic, histopathological findings, and cytokine production in the duodenum of Crohn's disease patients. (PubMed id 19120897)1 Ando T....Goto H. (2008)
    1137. Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. (PubMed id 18571457)1 Sadik C.D....Muhl H. (2008)
    1138. Chronic inflammation and mortality in haemodialysis: effect of different renal replacement therapies. Results from the RISCAVID study. (PubMed id 18305316)1 Panichi V....Palla R. (2008)
    1139. Reference gene selection for real-time polymerase chain reaction in human lung cells subjected to cyclic mechanical strain. (PubMed id 18785913)1 Pinhu L....Griffiths M.J. (2008)
    1140. Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells. (PubMed id 18234802)1 Hsu M....Chang Y. (2008)
    1141. The altered expression of inflammation-related molecules and secretion of IL-6 and IL-8 by HUVEC from newborns with maternal inactive systemic lupus erythematosus is modified by estrogens. (PubMed id 19029276)1 Rodriguez E....MontaA+o L.F. (2008)
    1142. Association of anemia and erythropoiesis stimulating agents with inflammatory biomarkers in chronic kidney disease. (PubMed id 18547996)1 Keithi-Reddy S.R....Singh A.K. (2008)
    1143. Translationally regulated C/EBP beta isoform expression upregulates metastatic genes in hormone-independent prostate cancer cells. (PubMed id 18512730)1 Kim M.H. and Field J. (2008)
    1144. Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris. (PubMed id 18463682)1 Nakatsuji T....Huang C.M. (2008)
    1145. Oxidative inactivation of the proteasome in retinal pigment epithelial cells. A potential link between oxidative stress and up-regulation of interleukin-8. (PubMed id 18502748)1 Fernandes A.F....Shang F. (2008)
    1146. The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection. (PubMed id 18426885)1 Buchholz K.R. and Stephens R.S. (2008)
    1147. Contribution of GM-CSF and IL-8 to the CD44-induced differentiation of acute monoblastic leukemia. (PubMed id 17914409)1 Delaunay J....Smadja-Joffe F. (2008)
    1148. Cord blood cytokine levels in neonates born to mothers with prolonged premature rupture of membranes and its relationship with morbidity and mortality. (PubMed id 18299272)1 Satar M....Cetiner S. (2008)
    1149. IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa. (PubMed id 17944600)1 Groux-Degroote S.... Delannoy P. (2008)
    1150. Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. (PubMed id 18824549)1 Hartl D....Elias J.A. (2008)
    1151. [Effect of fibrinogen on the secretion of interleukin -1beta and - 8 by polymorphonuclear leukocytes]. (PubMed id 18380966)1 Ge S....Meng S. (2008)
    1152. Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures. (PubMed id 18441098)1 Sabnis A.S....Yost G.S. (2008)
    1153. The protease-activated receptor-3 (PAR-3) can signal autonomously to induce interleukin-8 release. (PubMed id 18264801)1 Ostrowska E. and Reiser G. (2008)
    1154. The IL-8 protease SpyCEP/ScpC of group A Streptococcu s promotes resistance to neutrophil killing. (PubMed id 18692776)1 Zinkernagel A.S....Nizet V. (2008)
    1155. HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity. (PubMed id 18799285)1 Akeno N....Tomer Y. (2008)
    1156. The chemokine interleukin-8 and the surface activatio n protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia. (PubMed id 19383348)1 Hantschel O....Superti-Furga G. (2008)
    1157. Macrophage migration inhibitory factor and interleukin-8 produced by gastric epithelial cells during Helicobacter pylori exposure induce expression and activation of the epidermal growth factor receptor. (PubMed id 18474653)1 Beswick E.J. and Reyes V.E. (2008)
    1158. Angiopoietin-1 promotes endothelial cell proliferation and migration through AP-1-dependent autocrine production of interleukin-8. (PubMed id 18252863)1 Abdel-Malak N.A....Hussain S.N. (2008)
    1159. PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway. (PubMed id 18523665)1 Vij N....Mohan R.R. (2008)
    1160. [Effect of co-culture of bone marrow mesenchymal stem cells and K562 cells on expression of interleukin 8] (PubMed id 18315921)1 Wang L.X....Li J.Y. (2008)
    1161. Leptin receptor-related immune response in colorectal tumors: the role of colonocytes and interleukin-8. (PubMed id 19010917)1 Abolhassani M....Sobhani I. (2008)
    1162. Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis. (PubMed id 18780829)1 Wilson C....Waugh D.J. (2008)
    1163. Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB. (PubMed id 18074095)1 Oem J.K....Liu Q. (2008)
    1164. Protease-activated receptor (PAR)-induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK. (PubMed id 18086557)1 Ostrowska E. and Reiser G. (2008)
    1165. Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant. (PubMed id 18025101)1 Dias I.H....Griffiths H.R. (2008)
    1166. Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. (PubMed id 18703508)1 Balloy V....Chignard M. (2008)
    1167. Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta. (PubMed id 18617617)1 Chen S.U....Yang Y.S. (2008)
    1168. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)