IL8 Gene
protein-coding GIFtS : 71
GCID: GC04 P074595
interleukin 8
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Aliasesfor IL8 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Interleukin 8 1 2 K601 CXCL81 2 3 SCYB81 GCP-11 2 3 TSG-11 MDNCF1 2 3 B-ENAP1 MONAP1 2 3 Alveolar Macrophage Chemotactic Factor I2 NAP-11 2 3 Beta Endothelial Cell-Derived Neutrophil Activating Peptide2 GCP11 2 Beta-Thromboglobulin-Like Protein2 LECT1 2 Chemokine (C-X-C Motif) Ligand 82 LUCT1 2 Emoctakin3 LYNAP1 2 Interleukin-81 NAF1 2 Lung Giant Cell Carcinoma-Derived Chemotactic Protein2 NAP11 2 Lymphocyte Derived Neutrophil Activating Peptide2 IL-81 3 Neutrophil-Activating Peptide 12 Granulocyte Chemotactic Protein 12 3 Small Inducible Cytokine Subfamily B, Member 82 Monocyte-Derived Neutrophil Chemotactic Factor2 3 Tumor Necrosis Factor-Induced Gene 12 Monocyte-Derived Neutrophil-Activating Peptide2 3 Emoctakin3 T-Cell Chemotactic Factor2 3 C-X-C Motif Chemokine 83 3-10C1 Neutrophil-Activating Protein 13 AMCF-I1 Protein 3-10C3
Export aliases for IL8 gene to outside databases Previous GC identifers: GC04P074845 GC04P075006 GC04P075072 GC04P074971 GC04P070417
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Summariesfor IL8 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for IL8 : The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: IL8_HUMAN, P10145 Function : IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is alsoinvolved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively Gene Wiki entry for IL8 (Interleukin 8)
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Genomic Viewsfor IL8 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000004.11 NC_018915.1 NT_022778.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the IL8 gene promoter: GR AML1a HNF-4alpha2 NF-E2 p45 HNF-4alpha1 C/EBPalpha GR-alpha NF-E2 Other transcription factors Search SABiosciences Chromatin IP Primers for IL8 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL8
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 4q13-q21 Ensembl cytogenetic band: 4q13.3 HGNC cytogenetic band: 4q13-q21 IL8 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 4 GeneLoc Exon Structure
GeneLoc location for GC04P074595: view genomic region
(about GC identifiers )
Start:
74,606,223 bp from pter
End:
74,609,433 bp from pter
Size:
3,211 bases
Orientation:
plus strand
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Proteinsfor IL8 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: IL8_HUMAN, P10145 (See
protein sequence )Recommended Name: Interleukin-8 precursor Size : 99 amino acids; 11098 Da
Subunit : Homodimer
Subcellular location : Secreted
6/10 PDB 3D structures from and Proteopedia for IL8 (see all 10 ):1ICW (3D)
  1IKL (3D)
  1IKM (3D)
  1IL8 (3D)
  1ILP (3D)
  1ILQ (3D)
 
Secondary accessions : B2R4L8 Q6FGF6 Q6LAE6 Q96RG6 Q9C077 Q9UCE1 Q9UCR8 Q9UCR9 Q9UCS0Alternative splicing : 2 isoforms : P10145-1 P10145-2 Explore the universe of human proteins at neXtProt for IL8: NX_P10145 Post-translational modifications:
Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form1
Citrullination at Arg-27 prevents proteolysis, and dampens tissue inflammation, it also enhances leukocytosis, possibly through impaired chemokine clearance from the blood circulation1
View neXtProt modification sites for NX_P10145 IL8 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_000575.1 ENSEMBL proteins: ENSP00000306512 ENSP00000385908 Reactome Protein details: P10145 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
IL8 for ontologies About GeneDecksing IL8 Antibody Products: EMD Millipore Mono- and Polyclonal Antibodies for the study of IL8 R&D Systems Antibodies for IL8 (CXCL8/IL-8) Cell Signaling Technology (CST) Antibodies for IL8   OriGene Antibodies (see all 3 ): IL8 OriGene Custom Antibody Services for IL8 GenScript Superior Antibodies for IL8 Novus Biologicals IL8 Antibodies Abcam antibodies for IL8 Uscn Antibodies for IL8 ThermoFisher Antibody for IL8
Assay Products for IL8:
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Protein
Domains / Familiesfor IL8 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
IL8 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry P10145 ProtoNet protein and cluster: P10145
1 Blocks protein family : IPB002473 Interleukin-8 signature UniProtKB/Swiss-Prot: IL8_HUMAN, P10145 Similarity : Belongs to the intercrine alpha (chemokine CxC) family
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Functionfor IL8 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: IL8_HUMAN, P10145 Function : IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is alsoinvolved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively Induction : By ER stress in a DDIT3/CHOP-dependent manner
Genatlas biochemistry entry for IL8 : interleukin 8 (see IMC2@),neutrophil activating peptide 1,monocyte-derived neutrophil chemotactic factor,with a direct growth potentiating activity in malignant mesothelioma Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for IL8 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for IL8OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: IL8 (NM_000584 ) Sino Biological Human cDNA Clone for IL8 DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL8 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat IL8
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL8
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
IL8 for ontologies About GeneDecksing 2 GenomeRNAi human phenotypes for IL8 :Animal Models: Mouse knock-out Il8 tm1Lira for IL8 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Il8) :
IL8 for phenotypes About GeneDecksing
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Pathways & Interactionsfor IL8 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/52 super-pathways (see all 52 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 PEDF Induced Signaling 2 TGF-Beta Pathway 3 Class A/1 (Rhodopsin-like receptors) 4 Toll-like receptor signaling pathway 5 Mucin expression in CF via IL-6, IL-17 signaling pathways
Pathway sources See GeneCards unified pathways Show all pathways 5/8 EMD Millipore Pathways for IL8 (see all 8 )1 R&D Systems Pathway for IL8 5/27 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IL8 (see all 27 )1
Cell Signaling Technology (CST) Pathway for IL8 5/14 GeneGo (Thomson Reuters) Pathways for IL8 (see all 14 )5/13 BioSystems Pathways for IL8 (see all 13 ) 5/13
Reactome Pathways for IL8 (see all 13 )5/16
Kegg Pathways (Kegg details for IL8) (see all 16 ):
IL8 for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL8 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/93 Interacting proteins for IL8 (P10145 3 ENSP00000306512 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 93 )About this table Gene Ontology (GO): 5/27 biological process terms (GO ID links to tree view) (see all 27 ): About this table
IL8 for ontologies About GeneDecksing
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Drugs & Compoundsfor IL8 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
IL8 for compounds About GeneDecksing Browse Tocris compounds for IL8 2 HMDB Compounds for IL8 About this table 10/138 Novoseek chemical compound relationships for IL8 gene (see all 138 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
rantes
92.7
1369
9723955 (8), 17207890 (7), 10619832 (7), 16413378 (6) (see all 99 )
groalpha
86.1
191
11495082 (7), 9641651 (7), 17922696 (5), 9889409 (4) (see all 81 )
fmlp
79.7
471
7837814 (9), 16249234 (7), 15494208 (5), 9013980 (5) (see all 99 )
leukotriene b4
78.5
560
8003341 (9), 8973284 (5), 9482389 (5), 12149532 (5) (see all 99 )
vegf
76.4
1297
11234901 (9), 10334214 (9), 17349553 (8), 9457313 (8) (see all 99 )
endotoxin
74.4
268
2007851 (5), 11451261 (5), 18485432 (4), 16384605 (4) (see all 99 )
grogamma
72.8
23
8702798 (3), 15832427 (2), 9553055 (2), 10695618 (1) (see all 11 )
grobeta
68
26
10600366 (3), 8702798 (3), 15832427 (2), 9553055 (2) (see all 12 )
il 10
67.4
70
18363812 (4), 9543183 (2), 19723087 (2), 20041183 (2) (see all 56 )
lipoteichoic acid
67.3
89
10570304 (7), 16619004 (4), 8262617 (4), 19250704 (3) (see all 37 )
Search CenterWatch for drugs/clinical trials and news about IL8
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Transcriptsfor IL8 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for IL8 gene: NM_000584.3 Unigene Cluster for IL8:
Interleukin 8 Hs.624 [show with all ESTs ] Unigene Representative Sequence: NM_000584 3 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000307407 (uc003hhe.3 ) ENST00000401931 ENST00000483500 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for IL8 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for IL8OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: IL8 (NM_000584 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL8 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat IL8
Additional cDNA sequence: AK131067.1 AK311874.1 BC013615.1 BT007067.1 CR542151.1 M17017.1 M26383.1 Y00787.1 Z11686.1
23 DOTS entries : DT.92451091 DT.452985
DT.121222191 DT.100764374 DT.121222188 DT.100890247 DT.121222199 DT.97822713 DT.121222180 DT.100722366 DT.121222165 DT.100890251 DT.92451100 DT.95366903 DT.100890241 DT.100890254 DT.121222196 DT.92451094 DT.92451101 DT.100890252 DT.100890257 DT.100890262 DT.92451080 24/756 AceView cDNA sequences (see all 756 ):
AA362358 AA381584 CB306060 BX358167 CR601902 AW780211 BE122713 BQ101101 AA362192 BQ431044 CA308318 AA381931 CR595357 BM887846 BM055300 AA362139 BM955893 BM924085 AA381252 AA362196 CR623683 AA381576 AA381435 BQ051231 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for IL8 About this scheme ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b SP1 :                 SP2 :       -           SP3 :                
ECgene alternative splicing isoforms for IL8
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Expression for IL8 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IL8 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGGAAGCACT
About this image IL8 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See IL8 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IL8 SOURCE GeneReport for Unigene cluster: Hs.624 SABiosciences Expression via Pathway-Focused PCR Arrays including IL8 (see all 24 ): HIV Host Response in human mouse rat Antiviral Response in human mouse rat Nitric Oxide Signaling Pathway in human mouse rat T-cell & B-cell Activation in human mouse rat Stress & Toxicity PathwayFinder in human mouse rat
Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for IL8Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse / rat IL8 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat IL8 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat IL8 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL8
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Orthologsfor IL8 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for IL8 gene from 2/7 species (see all 7 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
IL81
interleukin 8
60.76(n) 52.08(a)
 
396495 NM_205498.1 NP_990829.1
lizard (Anolis carolinensis)
Reptilia
IL86
--
42(a)
1 ↔ 1
AAWZ02035874(23277-25185)
ENSEMBL Gene Tree for IL8 (if available)TreeFam Gene Tree for IL8 (if available)
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Paralogsfor IL8 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IL8 gene PPBP 2 PF4 2 CXCL1 2 PF4V1 2 CXCL6 2 CXCL3 2 CXCL5 2 CXCL2 2 18/25 SIMAP similar genes for IL8 using alignment to 2 protein entries: IL8_HUMAN (see all proteins )
(see all similar genes ):CXCL6 CXCL5 PPBP PF4 CXCL1 CXCL2 CXCL12 CXCL3 PF4V1 CCL8 CCL3L1 CCL3L3 CCL11 CCL18 CCL5 CXCL13 CXCL10 CCL2
IL8 for paralogs About GeneDecksing
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Genomic Variantsfor IL8 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Human Gene Mutation Database (HGMD) : IL8 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing IL8
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Disorders
/ Diseasesfor IL8 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
IL8 for disorders About GeneDecksing
OMIM gene information: 146930
OMIM disorders : --20/434 diseases for IL8 (see all 434 ): About MalaCards lung giant cell carcinoma neutrophil-specific granule deficiency bronchiolitis specific granule deficiency erythema elevatum diutinum muckle-wells syndrome alpha 1-antitrypsin deficiency estrogen-receptor negative breast cancer stenotrophomonas maltophilia zollinger-ellison syndrome glycogen storage disease type ia large granular lymphocyte leukemia adult-onset still's disease relapsing-remitting multiple sclerosis extrinsic allergic alveolitis cryptogenic organizing pneumonia common cold diffuse large b-cell lymphoma mycobacterium marinum hypersensitivity reaction type ii disease 13 diseases from the University of Copenhagen DISEASES database for IL8 :Lung disease Cancer Gastritis Cystic fibrosis Vascular disease Periodontitis Chorioamnionitis Inflammatory bowel disease Arthritis Mastitis Endometriosis Psoriasis Peptic ulcer 10/98 Novoseek disease relationships for IL8 gene (see all 98 ) About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
necrosis
91.7
3968
9462219 (9), 8601968 (6), 10740342 (5), 1702929 (4) (see all 99 )
inflammation
90.2
1154
12697917 (4), 10680520 (4), 15104334 (4), 15901266 (4) (see all 99 )
tumors
81.8
3953
11181444 (8), 8601968 (6), 12471616 (6), 16088182 (5) (see all 99 )
bronchoalveolar lavage fluid
72.9
158
7712280 (4), 10933164 (3), 16077402 (3), 15909061 (3) (see all 99 )
systemic inflammatory response syndrome
70.3
31
8143477 (2), 9558403 (2), 9038289 (2), 16227031 (2) (see all 21 )
pulmonary disease chronic obstructive
68
39
8563494 (2), 12915744 (2), 11108181 (2), 16181530 (2) (see all 27 )
sepsis
66.2
233
1612748 (6), 17368039 (5), 15730597 (5), 9120108 (4) (see all 99 )
cystic fibrosis
65.2
102
7940424 (6), 7639556 (3), 8476069 (3), 17880760 (2) (see all 65 )
rheumatoid arthritis
64.5
130
1932367 (2), 8961381 (2), 14750259 (2), 10437780 (2) (see all 94 )
airways disease
63.8
23
7927669 (2), 10417151 (1), 10460760 (1), 9199432 (1) (see all 14 )
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About This Section PubMed articles for IL8 gene, integrated from 9 sources (see all 7102 ) (see top 10 ): (articles sorted by number of sources associating them with IL8) Utopia : connect your pdf to the dynamic world of online information
The neutrophil-activating proteins interleukin 8 and beta- thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms. (PubMed id 2145175) 1 , 2 , 9 van Damme J.... Billiau A. (1990) Polymorphisms of the IL-8 and CXCR2 genes are not associated with Behcet's disease. (PubMed id 15630732) 1 , 4, 9 Duymaz-Tozkir J....Gul A. (2005) Genetic variation in the interleukin-8 gene promoter and vaginal concentrations of interleukin-8 are not associated with bacterial vaginosis during pregnancy. (PubMed id 16038986) 1 , 4, 9 Diaz-Cueto L....Arechavaleta-Velasco F. (2005) Relation of tumor necrosis factor (TNF) gene polymorphisms with serum concentrations and in vitro production of TNF-alpha and interleukin-8 in heavy drinkers. (PubMed id 15902922) 1 , 4, 9 Gonzalez-Quintela A....Perez L.F. (2004) Association study suggests opposite effects of polymorphisms within IL8 on bronchial asthma and respiratory syncytial virus bronchiolitis. (PubMed id 15356575) 1 , 4, 9 Heinzmann A....Deichmann K.A. (2004) Genetic association analysis of the IGFBP7, ADAMTS3, and IL8 genes as the potential osteoarthritis susceptibility that maps to chromosome 4q. (PubMed id 15708897) 1 , 4, 9 Kawahara C....Loughlin J. (2005) Influence of cytokine and ICAM-1 gene polymorphisms on susceptibility to chronic pancreatitis. (PubMed id 15917409) 1 , 4, 9 Howell W.M....Bateman A.C. (2005) Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. (PubMed id 16284368) 1 , 4, 9 Taguchi A....Goto H. (2005) Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma. (PubMed id 15598788) 1 , 4, 9 Savage S.A....Chanock S.J. (2004) Interleukin 8 gene polymorphism is associated with increased risk of nephritis in cutaneous vasculitis. (PubMed id 12415593) 1 , 4, 9 Amoli M.M....Gonzalez-Gay M.A. (2002) The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. (PubMed id 15710978) 1 , 4, 9 Ohyauchi M....Shimosegawa T. (2005) Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia. (PubMed id 16107886) 1 , 4, 9 Lehrnbecher T....Schwabe D. (2005) Genetic polymorphism of interleukin-8 (IL-8) is associated with Helicobacter pylori-induced duodenal ulcer. (PubMed id 15627645) 1 , 4, 9 Gyulai Z....Mandi Y. (2004) [Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis] (PubMed id 15220553) 1 , 4, 9 Kim M.S....Lee M.S. (2004) Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO- alpha and leaves RANTES and MCP-2 intact. (PubMed id 11023497) 1 , 2 , 9 Van den Steen P.E.... Opdenakker G. (2000) Structure and activity of a chimeric interleukin-8-melanoma-growth- stimulatory-activity protein. (PubMed id 8631339) 1 , 2 , 9 Sticht H.... Rosch P. (1996) Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. (PubMed id 2007144) 1 , 2 , 9 Clark-Lewis I....Aebersold R. (1991) Citrullination of CXCL8 increases this chemokine's ab ility to mobilize neutrophils into the blood circulation. (PubMed id 19608678) 1 , 2 Loos T....Proost P. (2009) Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. (PubMed id 18710930) 1 , 2 Proost P....Van Damme J. (2008) Polymorphisms in the interleukin-8 gene in patients with chronic obstructive pulmonary disease. (PubMed id 16007706) 1 , 4 Arinir U....Schultze-Werninghaus G. (2005) Significant association of interleukin 8 -251T/A polymorphism with smoking behavior in a Japanese population. (PubMed id 16195815) 1 , 4 Ito H....Tajima K. (2005) Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. (PubMed id 15579481) 1 , 4 Lu W....You W. (2005) The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. (PubMed id 16166417) 1 , 4 Lee W.P....Lee S.D. (2005) CD14 receptor polymorphism and Alzheimer's disease risk. (PubMed id 15854776) 1 , 4 Combarros O....Berciano J. (2005) Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival. (PubMed id 16110031) 1 , 4 Leibovici D....Wu X. (2005) Interleukin-8, intercellular adhesion molecule-1 and tumour necrosis factor-alpha gene polymorphisms and the risk for multiple system atrophy. (PubMed id 15607204) 1 , 4 Infante J....Combarros O. (2005) Genetic predisposition for a compromised immune system after multiple trauma. (PubMed id 16317381) 1 , 4 Hildebrand F....Stuhrmann M. (2005) Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease. (PubMed id 16313297) 1 , 4 Chen R.H....Tsai F.J. (2005) Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer. (PubMed id 14604894) 1 , 4 Campa D....Canzian F. (2004) Cytokine gene polymorphisms and breast cancer susceptibility and prognosis. (PubMed id 15265021) 1 , 4 Smith K.C....Howell W.M. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish. (PubMed id 15120188) 1 , 4 Ross O.A....Gibson J.M. (2004) Ethnic differences in allele distribution for the IL8 and IL1B genes in populations from eastern India. (PubMed id 15222686) 1 , 4 Chakravorty M....Roychoudhury S. (2004) Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease. (PubMed id 12870115) 1 , 4 Ma X....Graviss E.A. (2003) Regulation of the immune response by the interaction of chemokines and proteases. (PubMed id 14711052) 1 , 2 Struyf S.... Van Damme J. (2003) Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor region. (PubMed id 12898436) 1 , 4 Jiang Z.D....Milewicz D.M. (2003) High anti-Helicobacter pylori antibody seropositivity associated with the combination of IL-8-251TT and IL-10-819TT genotypes. (PubMed id 12662377) 1 , 4 Hamajima N....Tominaga S. (2003) Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. (PubMed id 12839942) 1 , 4 Landi S....Canzian F. (2003) Study of age-association with cytokine gene polymorphisms in an aged Irish population. (PubMed id 12633940) 1 , 4 Ross O.A....Rea I.M. (2003) Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma. (PubMed id 14675394) 1 , 4 Howell W.M....Bateman A.C. (2003) Influence of cytokine gene polymorphisms on the development of prostate cancer. (PubMed id 12067976) 1 , 4 McCarron S.L....Howell W.M. (2002) A novel interleukin-8 polymorphism is associated with severe systemic lupus erythematosus nephritis. (PubMed id 12081586) 1 , 4 Rovin B.H....Zhang X. (2002) Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma. (PubMed id 11978786) 1 , 2 Schutyser E.... Van Damme J. (2002) Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families. (PubMed id 11083887) 1 , 4 Hull J....Kwiatkowski D. (2000) Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 A resolution. (PubMed id 10707023) 1 , 2 Gerber N.... Eigenbrot C. (2000) Structure of a CXC chemokine-receptor fragment in complex with interleukin-8. (PubMed id 10368283) 1 , 2 Skelton N.J.... Lowman H. (1999) Interleukin-8, a chemotactic and inflammatory cytokine. (PubMed id 1639201) 1 , 2 Baggiolini M. and Clark-Lewis I. (1992) Crystal structure of interleukin 8: symbiosis of NMR and crystallography. (PubMed id 1988949) 1 , 2 Baldwin E.T.... Gronenborn A.M. (1991) Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8. Possible implications for the mechanism of receptor binding. (PubMed id 2005614) 1 , 2 Clore G.M. and Gronenborn A.M. (1991) Crystallization of human interleukin-8. A protein chemotactic for neutrophils and T-lymphocytes. (PubMed id 2182630) 1 , 2 Baldwin E.T.... Weber I.T. (1990) Three-dimensional structure of interleukin 8 in solution. (PubMed id 2184886) 1 , 2 Clore G.M.... Gronenborn A.M. (1990) Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. (PubMed id 2212672) 1 , 2 Hebert C.A.... Baker J.B. (1990) Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes. (PubMed id 2200751) 1 , 2 Hotta K....Suzuki K. (1990) Three forms of monocyte-derived neutrophil chemotactic factor (MDNCF) distinguished by different lengths of the amino-terminal sequence. (PubMed id 2648135) 1 , 2 Yoshimura T.... Leonard E.J. (1989) Purification and partial primary sequence of a chemotactic protein for polymorphonuclear leukocytes derived from human lung giant cell carcinoma LU65C cells. (PubMed id 2659722) 1 , 2 Suzuki K....Mizuno S. (1989) Determination of the secondary structure of interleukin-8 by nuclear magnetic resonance spectroscopy. (PubMed id 2681204) 1 , 2 Clore G.M.... Gronenborn A.M. (1989) Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes. (PubMed id 2664463) 1 , 2 Kowalski J. and Denhardt D.T. (1989) Purification of granulocyte chemotactic peptide/interleukin-8 reveals N-terminal sequence heterogeneity similar to that of beta- thromboglobulin. (PubMed id 2523801) 1 , 2 van Damme J.... Billiau A. (1989) Inflammatory cytokines induce synthesis and secretion of gro protein and a neutrophil chemotactic factor but not beta 2-microglobulin in human synovial cells and fibroblasts. (PubMed id 2655583) 1 , 2 Golds E.E.... Nyirkos P. (1989) Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. (PubMed id 2663993) 1 , 2 Mukaida N.... Matsushima K. (1989) Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. (PubMed id 3260265) 1 , 2 Matsushima K.... Oppenheim J.J. (1988) Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP). (PubMed id 3279957) 1 , 2 Gregory H.... Christophers E. (1988) Induction of mRNA for a serine protease and a beta-thromboglobulin- like protein in mitogen-stimulated human leukocytes. (PubMed id 2953813) 1 , 2 Schmid J. and Weissmann C. (1987) Purification and amino acid sequencing of NAF, a novel neutrophil- activating factor produced by monocytes. (PubMed id 3322281) 1 , 2 Walz A.... Baggiolini M. (1987) Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines. (PubMed id 3480540) 1 , 2 Yoshimura T.... Leonard E.J. (1987) [Effect of different intermittent hypoxia patterns on interleukin-6 and interleukin-8 levels of human umbilical vein endothelial cel ls.] (PubMed id 20398511) 1 , 9 Li Y.M....Dong L.X. (2010) Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor. (PubMed id 17671691) 1 , 9 Kamohara H....Baba H. (2007) [Levels and mRNA expression of interleukin-8 in gastric and duodenal mucosa of children Infected with Helicobacter pylori] (PubMed id 14756945) 1 , 9 Chen J....Chen F.B. (2003) Reciprocal regulation of 5alpha-dihydrotestosterone, interleukin-6 and interleukin-8 during proliferation of epithelial ovarian carcinoma. (PubMed id 17617741) 1 , 9 Wang Y....Yao Z. (2007) Human microvascular endothelial synthesis of interleu kin-8 during in vitro ischemia and reperfusion. (PubMed id 16927373) 1 , 9 Albadawi H....Watkins M.T. (2007) Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue. (PubMed id 13129857) 1 , 9 Bruun J.M....Richelsen B. (2004) Exaggerated IL-8 and IL-6 responses to TNF-alpha by parainfluenza virus type 4-infected NCI-H292 cells. (PubMed id 15273081) 1 , 9 Roger T....Lutter R. (2004) Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. (PubMed id 11855786) 1 , 9 Ozturk O....Isbir T. (2001) Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and incr eases the efficacy of chemotherapeutic drugs. (PubMed id 19646263) 1 , 9 Singh R.K. and Lokeshwar B.L. (2009) Prognostic value of serum level of interleukin-6 and interleukin-8 in metastatic breast cancer patients. (PubMed id 18689272) 1 , 9 Ahmed O.I....Gobran N.S. (2006) Lipopolysaccharide induces interleukin-8 production by human cervical smooth muscle cells. (PubMed id 12594001) 1 , 9 Watari M....Fujimoto S. (2003) The expression of IL-8 and IL-8 receptors in pancreat ic adenocarcinomas and pancreatic neuroendocrine tumours. (PubMed id 20005738) 1 , 9 Hussain F....El-Bahrawy M. (2010) IL-8 amplifies CD40/CD154-mediated ICAM-1 production via the CXCR-1 receptor and p38-MAPK pathway in human renal proximal tubule cells. (PubMed id 18667484) 1 , 9 Li H. and Nord E.P. (2009) Reciprocal regulation of 17beta-estradiol, interleukin-6 and interleukin-8 during growth and progression of epithelial ovarian cancer. (PubMed id 19401270) 1 , 9 Yang J....Yao Z. (2009) [High mobility group box-1 stimulates proinflammatory cytokine production in endothelial cells via MAP kinases] (PubMed id 19726280) 1 , 9 Zhong T.Y....Jiang Y. (2009) Relationships between hepatitis C virus replication and CXCL-8 production in vitro. (PubMed id 16873245) 1 , 9 Koo B.C....Polyak S.J. (2006) [Time-dependent increase of interleukin-8 production in endothelial cells exposed to fluid shear stress] (PubMed id 15022458) 1 , 9 Tang R....Chen H. (2004) Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men. (PubMed id 12720537) 1 , 9 Bruun J.M....Richelsen B. (2003) Estradiol increases IL-8 secretion of normal human breast tissue and breast cancer in vivo. (PubMed id 19109168) 1 , 9 Bendrik C. and Dabrosin C. (2009) Serum and urine levels of interleukin-8 in patients with non-Hodgkin's lymphoma. (PubMed id 18502145) 1 , 9 Lee H.L....Kong S.Y. (2008) Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and NF-kappaB pathways. (PubMed id 18275043) 1 , 9 Bischoff D.S....Yamaguchi D.T. (2008) Regulation of interleukin-8 gene expression by interleukin-1beta, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells. (PubMed id 8663179) 1 , 9 Chaudhary L.R. and Avioli L.V. (1996) Expression of interleukin-8 and monocyte chemotactic protein 1 in women with endometriosis. (PubMed id 18314120) 1 , 9 Ulukus M....Arici A. (2009) Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells. (PubMed id 18671849) 1 , 9 Zhu Y.M....Woll P.J. (2008) Correlation of serum IL-6, IL-8 and IL-10 levels with clinicopathological features and prognosis in patients with diffuse large B-cell lymphoma. (PubMed id 18479302) 1 , 9 Nacinovic-Duletic A....Jonjic N. (2008) Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells. (PubMed id 17207890) 1 , 9 Henriquet C....Mathieu M. (2007) TGF-beta1 induces IL-8 and MCP-1 through a connective tissue growth factor-independent pathway. (PubMed id 16204411) 1 , 9 Qi W....Pollock C.A. (2006) Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism. (PubMed id 16795034) 1 , 9 Lin C.I....Lee H. (2006) Expression of interleukin-8 and monocyte chemotactic protein-1 in adenomyosis. (PubMed id 15979992) 1 , 9 Ulukus E.C....Arici A. (2005) Interleukin-17 induces hyperresponsive interleukin-8 and interleukin-6 production to tumor necrosis factor-alpha in structural lung cells. (PubMed id 15845864) 1 , 9 van den Berg A....Lutter R. (2005) Association of interleukin-8 and plasminogen activator system in the progression of colorectal cancer. (PubMed id 16088182) 1 , 9 Terada H....Konno H. (2005) Cytokine gene expression in human skeletal muscle during concentric contraction: evidence that IL-8, like IL-6, is influenced by glycogen availability. (PubMed id 15072962) 1 , 9 Chan M.H....Febbraio M.A. (2004) Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells. (PubMed id 12632066) 1 , 9 Kuwada Y....Chayama K. (2003) Elevated serum levels of interleukin-8 in advanced non-small cell lung cancer patients: relationship with prognosis. (PubMed id 12513912) 1 , 9 Orditura M....Galizia G. (2002) Normal and SV40 transfected human peritoneal mesothelial cells produce IL-6 and IL-8: implication for gynaecological disease. (PubMed id 12165085) 1 , 9 Zhang X.Y....Barton D.P. (2002) CD14-mediated induction of interleukin-8 and monocyte chemoattractant protein-1 by a heat-resistant constituent of Porphyromonas gingivalis in endothelial cells. (PubMed id 12410798) 1 , 9 Mao S....Oda H. (2002) [Dynamic changes of serum interleukin-6 and interleuk in-8 in patients with acute traumatic brain injury and the clinical significanc e] (PubMed id 19460731) 1 , 9 He L.M....Liu X.J. (2009) Upregulation of IL-6, IL-8 and CCL2 gene expression after acute inflammation: Correlation to clinical pain. (PubMed id 19233564) 1 , 9 Wang X.M....Dionne R.A. (2009) [Effects of TNF-alpha on MCP-1 and IL-8 mRNA Expression in Human Umbilical Vein Endothelial Cells.] (PubMed id 19379593) 1 , 9 Cheng H.T....Zhao J. (2009) Post-transcriptional regulation of TNF-induced expression of ICAM-1 and IL-8 in human lung microvascular endothelial cells: An obligatory role for the p38 MAPK-MK2 pathway dissociated with HSP27. (PubMed id 18486623) 1 , 9 Su X....Meng X. (2008) Expression and secretion of CXCL-8 and CXCL-10 from mycobacterium bovis BCG-infected human epithelial cells: role of IL-4. (PubMed id 16864907) 1 , 9 Mendez-Samperio P....Vazquez A. (2006) [The effect of TNF-alpha & IL-8 in the pathogenesis of allergic rhinitis] (PubMed id 17285966) 1 , 9 Wang Z. (2006) Lack of association of interleukin-6 and interleukin-8 gene polymorphisms in Chinese patients with systemic lupus erythematosus. (PubMed id 17115422) 1 , 9 Huang C.M....Tsai F.J. (2006) Interleukin-4 downregulates TNFalpha-induced IL-8 production in keratinocytes. (PubMed id 16004996) 1 , 9 Raingeaud J. and Pierre J. (2005) The CXC chemokine GCP-2/CXCL6 is predominantly induced in mesenchymal cells by interleukin-1beta and is down-regulated by interferon-gamma: comparison with interleukin-8/CXCL8. (PubMed id 12533683) 1 , 9 Wuyts A....Van Damme J. (2003) Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES. (PubMed id 12660426) 1 , 9 Aoki M....Kawana S. (2003) Peritoneal fluid concentrations of interleukin-8 in patients with endometriosis depend on the severity of the disorder and are higher in the luteal phase. (PubMed id 12615831) 1 , 9 Calhaz-Jorge C....Palma-Carlos M.L. (2003) Interleukin-8 and vascular endothelial growth factor mRNA and protein levels are down-regulated in ovarian carcinoma cells in serous effusions. (PubMed id 11964077) 1 , 9 Davidson B....Goldberg I. (2002) Signal mechanisms of vascular endothelial growth fact or and interleukin-8 in ovarian hyperstimulation syndrome: dopamine targets the ir common pathways. (PubMed id 20008399) 1 , 9 Chen S.U....Yang Y.S. (2010) IL-6, IL-8 and IL-10 levels in healthy weight and ove rweight children. (PubMed id 20190550) 1 , 9 Tam C.S....Baur L.A. (2010) Roles of reactive oxygen species in CXCL8 and CCL2 expression in response to the 30-kDa antigen of Mycobacterium tuberculosis. (PubMed id 18690522) 1 , 9 Lee H.M....Jo E.K. (2009) Induction of IL-8 expression by bacterial flagellin i s mediated through lipid raft formation and intracellular TLR5 activation in A5 49 cells. (PubMed id 19786303) 1 , 9 Im J....Han S.H. (2009) Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis. (PubMed id 19203362) 1 , 9 Zahn A....Ehehalt R. (2009) Effect of Helicobacter pylori infection on IL-8, IL-1beta and COX-2 expression in patients with chronic gastritis and gastric cancer. (PubMed id 18985541) 1 , 9 Bartchewsky W....Ribeiro M.L. (2009) Interleukin-8 and RANTES are signature cytokines made by HOZOT, a new type of regulatory T cells. (PubMed id 19699525) 1 , 9 Harashima A....Kibata M. (2009) Peptidoglycan-mediated IL-8 expression in human alveolar type II epithelial cells requires lipid raft formation and MAPK activation. (PubMed id 17997161) 1 , 9 Cheon I.S....Han S.H. (2008) Detection of gingival crevicular fluid cytokines in children and adolescents with and without fixed orthodontic appliances. (PubMed id 18568476) 1 , 9 Giannopoulou C....Kamma J. (2008) LPS induces interleukin-6 and interleukin-8 but not tumor necrosis factor-alpha in human adipocytes. (PubMed id 18060802) 1 , 9 Hoch M....Linscheid P. (2008) Impact of weight loss on circulating IL-1, IL-6, IL-8, TNF-alpha, VEGF-A, VEGF-C and midkine in gastroesophageal cancer patients. (PubMed id 17931612) 1 , 9 Krzystek-Korpacka M....Banas T. (2007) Synergistic effect of PGD2 via prostanoid DP receptor on TNF-alpha-induced production of MCP-1 and IL-8 in human monocytic THP-1 cells. (PubMed id 17307163) 1 , 9 Hirano Y....Arimura A. (2007) Serum IL-1beta, IL-6, IL-8, and TNF-alpha levels in early diagnosis and management of neonatal sepsis. (PubMed id 18274637) 1 , 9 Kurt A.N....Yilmaz E. (2007) IL-8 and IFN-gamma in tear fluid of patients with cystic fibrosis. (PubMed id 16487026) 1 , 9 Mrugacz M....Minarowska A. (2006) Polymorphisms in interleukin 8 and its receptors (IL8, IL8RA and IL8RB) and association of common IL8 receptor variants with peripheral blood eosinophil counts. (PubMed id 16897191) 1 , 9 Cheong H.S....Park C.S. (2006) Mast cell tryptase in mast cell granules enhances MCP-1 and interleukin-8 production in human endothelial cells. (PubMed id 15976326) 1 , 9 Kinoshita M....Matsumori A. (2005) Regulation of interleukin-8 expression in human endometrial endothelial cells: a potential mechanism for the pathogenesis of endometriosis. (PubMed id 15613411) 1 , 9 Luk J....Arici A. (2005) Bradykinin upregulates IL-8 production in human gingival fibroblasts stimulated by interleukin-1beta and tumor necrosis factor alpha. (PubMed id 15664665) 1 , 9 Brunius G....Yucel-Lindberg T. (2005) Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells. (PubMed id 15321994) 1 , 9 Sebkova L....Luzza F. (2004) Augmented production of chemokines by the interaction of type II collagen-reactive T cells with rheumatoid synovial fibroblasts. (PubMed id 15077296) 1 , 9 Min D.J....Kim H.Y. (2004) Porphyromonas gingivalis modulates the production of interleukin 8 and monocyte chemotactic protein 1 in human vascular endothelial cells. (PubMed id 12520365) 1 , 9 Kobayashi-Sakamoto M....Hirose K. (2003) Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. (PubMed id 12391099) 1 , 9 Ohga E....Ouchi Y. (2003) Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. (PubMed id 12496258) 1 , 9 Heidemann J....Binion D.G. (2003) Inflammatory cytokines mediate C-C (monocyte chemotactic protein 1) and C-X-C (interleukin 8) chemokine expression in human pleural fibroblasts. (PubMed id 11989790) 1 , 9 Loghmani F....Antony V.B. (2002) Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells. (PubMed id 11784713) 1 , 9 Lee T.H....Avraham S. (2002) Receptor recognition and specificity of interleukin-8 is determined by residues that cluster near a surface-accessible hydrophobic pocket. (PubMed id 8626516) 1 , 9 Hammond M.E....Tekamp-Olson P. (1996) Differential expression of the chemokines GRO-2, GRO- 3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival. (PubMed id 20162422) 1 , 9 Doll D....Janssen K.P. (2010) Cytokines in bronchoalveolar lavage fluid and serum o f lung cancer patients during radiotherapy - Association of interleukin-8 and V EGF with survival. (PubMed id 20044268) 1 , 9 Crohns M....Kellokumpu-Lehtinen P. (2010) Very early posttraumatic serum alterations are signif icantly associated to initial massive RBC substitution, injury severity, multip le organ failure and adverse clinical outcome in multiple injured patients. (PubMed id 19661010) 1 , 9 Bogner V....Biberthaler P. (2009) A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin. (PubMed id 19794965) 1 , 9 Merighi S....Borea P.A. (2009) Macrolide antibiotics like azithromycin increase lipo polysaccharide-induced IL-8 production by human gingival fibroblasts. (PubMed id 19661014) 1 , 9 Kamemoto A....Wang P.L. 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(2009) Measurement of tumor necrosis factor-alpha, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease. (PubMed id 19436689) 1 , 9 Ko F.W....Hui D.S. (2009) Effects of peritoneal fluid from endometriosis patien ts on interferon-gamma-induced protein-10 (CXCL10) and interleukin-8 (CXCL8) re leased by neutrophils and CD4+ T cells. (PubMed id 19694638) 1 , 9 Kim J.Y....Lee K.S. (2009) Differential flow cytometric detection of intracellular cytokines in peripheral and peritoneal mononuclear cells of women with endometriosis. (PubMed id 17207568) 1 , 9 Gmyrek G.B....Chel/monska-Soyta A. (2008) Elevation of circulating interleukin-8 is related to lymph node and distant metastases in esophageal squamous cell carcinomas--implication for clinical evaluation of cancer patient. (PubMed id 18182303) 1 , 9 Krzystek-Korpacka M....Banas T. 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(2004) Differential roles for NF-kappa B in endotoxin and oxygen induction of interleukin-8 in the macrophage. (PubMed id 12909591) 1 , 9 D'Angio C.T....Finkelstein J.N. (2004) MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. (PubMed id 15069060) 1 , 9 Rhee S.H....Pothoulakis C. (2004) Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. (PubMed id 15534087) 1 , 9 Benoy I.H....Dirix L.Y. (2004) Interleukin-8 serum levels in patients with hepatocellular carcinoma: correlations with clinicopathological features and prognosis. (PubMed id 14676125) 1 , 9 Ren Y....Fan S.T. (2003) The primary role in biologic activity of the neutrophil chemokines IL-8 and GRO-alpha in cultured nasal epithelial cells. (PubMed id 12744776) 1 , 9 Rudack C....Schroeder J.M. (2003) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. (PubMed id 11854210) 1 , 9 Tamai R....Takada H. (2002) Protein kinase C and ERK activation are required for TFF-peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-alpha-induced interleukin-6 (IL-6) and IL-8 secretion. (PubMed id 11884401) 1 , 9 Graness A....Hoffmann W. (2002) Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate. (PubMed id 12151344) 1 , 9 Hellmuth M....Muhl H. (2002) Interleukin-8 and growth-regulated oncogene alpha mediate angiogenesis in Kaposi's sarcoma. (PubMed id 12388718) 1 , 9 Lane B.R....Markovitz D.M. (2002) Autocrine growth effect of IL-8 and GROalpha on a human pancreatic cancer cell line, Capan-1. (PubMed id 10881932) 1 , 9 Takamori H....Schraufstatter I.U. (2000) Influence of IL1B polymorphism on CpG island hypermet hylation in Helicobacter pylori-infected gastric cancer. (PubMed id 20405297) 1 , 9 Yoo E.J....Kang G.H. (2010) Proinflammatory cytokine IL-1beta stimulates IL-8 syn thesis in mast cells via a leukotriene B4 receptor 2-linked pathway, contributi ng to angiogenesis. (PubMed id 20194723) 1 , 9 Kim G.Y....Kim J.H. (2010) Lysophosphatidic acid up-regulates expression of grow th-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protei n-1 in human first-trimester trophoblasts: possible roles in angiogenesis and i mmune regulation. (PubMed id 19906815) 1 , 9 Chen S.U....Yang Y.S. (2010) Interleukin (IL)-1beta, IL-1 receptor antagonist, IL- 6, IL-8, IL-10, and tumor necrosis factor alpha gene polymorphisms in patients with febrile seizures. (PubMed id 20486195) 1 , 9 Chou I.C....Tsai F.J. (2010) Neutrophil expression of cyclooxygenase 2 in preeclam psia. (PubMed id 20220108) 1 , 9 Bachawaty T....Walsh S.W. (2010) Muscarinic M3 receptor stimulation increases cigarett e smoke-induced IL-8 secretion by human airway smooth muscle cells. (PubMed id 19460789) 1 , 9 Gosens R....Zuyderduyn S. (2009) Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. (PubMed id 18830271) 1 , 9 Watanabe H....Iijima M. (2009) [Effects of erythromycin on the synthesis of interleu kin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells] (PubMed id 19567187) 1 , 9 Yu L. and Ran P.X. (2009) Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytok ine genes. (PubMed id 19692203) 1 , 9 Reyes-Gibby C.C....Spitz M.R. (2009) ELISpot analysis of LPS-stimulated leukocytes: human granulocytes selectively secrete IL-8, MIP-1beta and TNF-alpha. (PubMed id 19358850) 1 , 9 Smedman C....Paulie S. (2009) Serum proinflammatory cytokine - interleukin-8 as pos sible infection site marker in preterm deliveries. (PubMed id 19591568) 1 , 9 Bogavac M.A. and BrkiA8 S. (2009) Lipoxin A4 inhibits IL-1beta-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells. (PubMed id 19357230) 1 , 9 Decker Y....Godson C. (2009) Dynamic changes of interleukin-8 network along the co lorectal adenoma-carcinoma sequence. (PubMed id 19350238) 1 , 9 Cui G....Florholmen J. (2009) Effect of sulfasalazine on basal and bacteria-stimulated interleukin-8 production by endocervical epithelial cells. (PubMed id 19239421) 1 , 9 Peltier M.R....Smulian J.C. (2009) Role of pro-/anti-inflammatory cytokines and their co rrelation with established risk factors in South Indians with coronary artery d isease. (PubMed id 18796448) 1 , 9 Rajappa M....Sharma A. (2009) Genetic polymorphisms of interleukin 8 and risk of ulcerative colitis in the Chinese population. (PubMed id 19348790) 1 , 9 Li K....Mao D. (2009) Ceramide-dependent PP2A regulation of TNF{alpha}-induced IL-8 production in respiratory epithelial cells. (PubMed id 19286927) 1 , 9 Cornell T.T....Shanley T.P. (2009) Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB. (PubMed id 19074641) 1 , 9 Rafiee P....Shaker R. (2009) Cytokine (IL-6) and chemokine (IL-8) gene polymorphisms among rheumatoid arthritis patients in Taiwan. (PubMed id 18799095) 1 , 9 Lo S.F....Tsai F.J. (2008) Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-kappaB-dependent manner. (PubMed id 18156286) 1 , 9 Puthia M.K....Tan K.S. (2008) Inhibition by salmeterol and cilomilast of fluticasone-enhanced IP-10 release in airway epithelial cells. (PubMed id 18259970) 1 , 9 Reddy P.J....Kelsen S.G. (2008) Inflammatory-activated microvascular endothelial cells regulate interleukin-8 and monocyte chemoattractant protein-1 expression of A549 cells in a paracrine fashion. (PubMed id 18266131) 1 , 9 Wendel M....Koch T. (2008) IL-8 induces imbalances between nitric oxide and endothelin-1, and also between plasminogen activator inhibitor-1 and tissue-type plasminogen activator in cultured endothelial cells. (PubMed id 18023202) 1 , 9 Cheng M....Chen H. (2008) Angiogenesis-related growth factors and cytokines in the serum of patients with B non-Hodgkin lymphoma; relation to clinical features and response to treatment. (PubMed id 18190463) 1 , 9 Passam F.H....Alexandrakis M.G. (2008) Expression of angiogenesis-related genes regulates different steps in the process of tumor growth and metastasis in human urothelial cell carcinoma of the urinary bladder. (PubMed id 19096229) 1 , 9 Chikazawa M....Shuin T. 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(2007) [Association between interleukin-8 gene-251 locus polymorphism and respiratory syncytial virus bronchiolitis and post-bronchiolitis wheezing in infants] (PubMed id 18282421) 1 , 9 Tian M....Chen R.H. (2007) Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils. (PubMed id 17550933) 1 , 9 Maneechotesuwan K....Barnes P.J. (2007) Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis. (PubMed id 17309748) 1 , 9 Hofner P....Mandi Y. (2007) Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2. (PubMed id 16820307) 1 , 9 Wang H. and He S. (2006) Cytokine gene polymorphisms in bullous pemphigoid in a Chinese population. (PubMed id 16403098) 1 , 9 Chang Y.T....Tsai S.F. (2006) Chemokines and incident coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. (PubMed id 16825597) 1 , 9 Herder C....Koenig W. (2006) Modulation of neutrophil apoptosis in plasma of patients after orthognathic surgery. (PubMed id 16289597) 1 , 9 Suzuki R....Nagumo M. (2006) IL-8 (-251 A/T) and CXCR2 (+1208 C/T) gene polymorphisms and risk of multiple sclerosis in Iranian patients. (PubMed id 16793206) 1 , 9 Kamali-Sarvestani E....Vessal M. (2006) Interleukin 6 and 8 levels in plasma and fibroblast cultures in psoriasis. (PubMed id 16864908) 1 , 9 Zalewska A....Sysa-Jedrzejowska A. (2006) Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer. (PubMed id 16937502) 1 , 9 Theodoropoulos G....Gazouli M. (2006) Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease. (PubMed id 16429233) 1 , 9 Matheson M.C....Abramson M.J. (2006) Polymorphism in the IL-8 gene, but not in the TLR4 gene, increases the severity of acute pancreatitis. (PubMed id 17124436) 1 , 9 Hofner P....Mandi Y. (2006) The role of interleukin-8 in cancer cells and microenvironment interaction. (PubMed id 15569594) 1 , 9 Yuan A....Yang P.C. (2005) Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein. (PubMed id 16164755) 1 , 9 Moorman J.P....Krishnaswamy G. (2005) A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells. (PubMed id 15661856) 1 , 9 Pae H.O....Chung H.T. (2005) GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells. (PubMed id 15609321) 1 , 9 Grzesiak J.J....Bouvet M. (2005) Inflammatory cytokine and thrombin regulation of interleukin-8 and intercellular adhesion molecule-1 expression in first trimester human decidua. (PubMed id 15914533) 1 , 9 Lockwood C.J....Schatz F. (2005) Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. (PubMed id 15641067) 1 , 9 Cecil D.L.... Liu-Bryan R. (2005) Cigarette smoke induces IL-8, but inhibits eotaxin and RANTES release from airway smooth muscle. (PubMed id 16029496) 1 , 9 Oltmanns U....Mitchell J.A. (2005) Secretion of interleukin-8 by human-derived cell lines infected with Mycobacterium bovis. (PubMed id 15203565) 1 , 9 Mendez-Samperio P....Garcia-Martinez E. (2004) Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. (PubMed id 14767470) 1 , 9 Lee L.F....Kung H.J. (2004) Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain. 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(2004) Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis. (PubMed id 15203561) 1 , 9 Bayraktaroglu T....Borazan A. (2004) Macrophage migration inhibitory factor up-regulates the expression of interleukin-8 messenger RNA in synovial fibroblasts of rheumatoid arthritis patients: common transcriptional regulatory mechanism between interleukin-8 and interleukin-1beta. (PubMed id 15146413) 1 , 9 Onodera S....Minami A. (2004) Distinct cytokine production by lung and blood neutrophils from children with cystic fibrosis. (PubMed id 12547728) 1 , 9 Corvol H....Clement A. (2003) Upregulation of interleukin-8 by hypoxia in human ovaries. (PubMed id 14672330) 1 , 9 Yoshino O....Taketani Y. (2003) Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-media ted synthesis of interleukin-8. 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(2003) Different affinities of glycosaminoglycan oligosaccha rides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites. (PubMed id 11814358) 1 , 9 Goger B....Kungl A.J. (2002) Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. (PubMed id 12359770) 1 , 9 Bendre M.S....Suva L.J. (2002) Cytokine regulation of constitutive production of interleukin-8 and -6 by human pancreatic cancer cell lines and serum cytokine concentrations in patients with pancreatic cancer. (PubMed id 12239630) 1 , 9 Wigmore S.J....Ross J.A. (2002) MCP-1, MIP-1, IL-8 and ischemic cerebral tissue enhance human bone marrow stromal cell migration in interface culture. (PubMed id 12186702) 1 , 9 Wang L....Chopp M. (2002) Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells. 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(1992) Association of interleukin-8 gene polymorphism with c achexia from patients with gastric cancer. (PubMed id 19929572) 1 , 9 Bo S....Xiaobo L. (2010) Constitutive NF-kappaB activity regulates the express ion of VEGF and IL-8 and tumor angiogenesis of human glioblastoma. (PubMed id 20127012) 1 , 9 Xie T.X....Huang S. (2010) IL-8 production by macrophages is synergistically enh anced when cigarette smoke is combined with TNF-alpha. (PubMed id 19874800) 1 , 9 Sarir H....Folkerts G. (2010) Impaired interleukin-8 chemokine secretion by staphyl ococcus aureus-activated epithelium and T-cell chemotaxis in cystic fibrosis. (PubMed id 19597126) 1 , 9 Al Alam D....Gangloff S.C. (2010) Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells. (PubMed id 19733855) 1 , 9 Choi K.H....Kim K. (2010) IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. (PubMed id 20026745) 1 , 9 Reeves E.P....McElvaney N.G. (2010) Pollen-induced oxidative stress influences both innat e and adaptive immune responses via altering dendritic cell functions. (PubMed id 20118277) 1 , 9 Csillag A....Bacsi A. (2010) Enteroaggregative Escherichia coli infection induces IL-8 production via activation of mitogen-activated protein kinases and the tra nscription factors NF-kappaB and AP-1 in INT-407 cells. (PubMed id 19898747) 1 , 9 Khan K....Ghosh S. (2010) Association of common polymorphisms in IL10, and in o ther genes related to inflammatory response and obesity with colorectal cancer. (PubMed id 19760027) 1 , 9 Tsilidis K.K....Platz E.A. (2009) Common polymorphisms in interleukin genes (IL4, IL6, IL8 and IL12) are not associated with alcoholic liver disease or alcoholism in Spanish men. (PubMed id 19185507) 1 , 9 Marcos M....Laso F.J. (2009) Oxidative stress causes IL8 promoter hyperacetylation in cystic fibrosis airway cell models. (PubMed id 18635816) 1 , 9 Bartling T.R. and Drumm M.L. (2009) Low concentrations of LL-37 alter IL-8 production by keratinocytes and bronchial epithelial cells in response to proinflammatory sti muli. (PubMed id 19527294) 1 , 9 Filewod N.C....Hancock R.E. (2009) Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling. (PubMed id 19157552) 1 , 9 Leung K.W....Tombran-Tink J. (2009) Specific NFkappaB subunit activation and kinetics of cytokine induction in adenoviral keratitis. (PubMed id 20038977) 1 , 9 Rajaiya J....Chodosh J. (2009) Targeted knockdown of EGR-1 inhibits IL-8 production and IL-8-mediated invasion of prostate cancer cells through suppressing EGR-1/N F-kappaB synergy. (PubMed id 19837667) 1 , 9 Ma J....Xiao W. (2009) Interleukin 8 gene polymorphisms and susceptibility to restenosis after percutaneous coronary intervention. (PubMed id 19404719) 1 , 9 Vogiatzi K....Spandidos D.A. (2009) Human airway smooth muscle cells from asthmatic indiv iduals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, a nd RNA polymerase II binding to the CXCL8 promoter. (PubMed id 19734226) 1 , 9 John A.E....Knox A.J. (2009) Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. (PubMed id 19015376) 1 , 9 SAcmiramoth N....Chollet-Martin S. (2009) Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells. (PubMed id 19028451) 1 , 9 Chung S.W....Kim K. (2009) Proteasome inactivation promotes p38 mitogen-activate d protein kinase-dependent phosphatidylinositol 3-kinase activation and increas es interleukin-8 production in retinal pigment epithelial cells. (PubMed id 19570915) 1 , 9 Fernandes A.F....Shang F. (2009) MicroRNAs miR-146a/b negatively modulate the senescen ce-associated inflammatory mediators IL-6 and IL-8. 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(2009) N-methyl-D-aspartate and sigma-ligands change the production of interleukins 8 and 10 in lymphocytes through modulation of the NMDA glutamate receptor. (PubMed id 19246943) 1 , 9 Kvaratskhelia E....Mikeladze D.G. (2009) [Association between interleukin-8 in lung tissues an d stages of chronic obstructive pulmonary diseases] (PubMed id 19950606) 1 , 9 Hu X.R....Wen F.Q. (2009) Asthma and genes encoding components of the vitamin D pathway. (PubMed id 19852851) 1 , 9 BossAc Y....Laprise C. (2009) [The role of CyPA in chemotaxis of neutrophil in rheumatoid arthritis and secretion of interleukin-8.] (PubMed id 19426598) 1 , 9 Zhang B....Zhu P. (2009) Interleukin-8 is essential for normal urothelial cell survival. (PubMed id 19535567) 1 , 9 Tseng-Rogenski S. and Liebert M. (2009) Identification of NR4A2 as a transcriptional activato r of IL-8 expression in human inflammatory arthritis. (PubMed id 19732956) 1 , 9 Aherne C.M....Murphy E.P. (2009) Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. (PubMed id 19267370) 1 , 9 Wang M.H....Platz E.A. (2009) The prolyl isomerase Pin1 regulates the NF-kappaB sig naling pathway and interleukin-8 expression in glioblastoma. (PubMed id 19668231) 1 , 9 Atkinson G.P....Benveniste E.N. (2009) Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. (PubMed id 19229069) 1 , 9 Hastings N.E....Blackman B.R. (2009) Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naA^ve ulcerative colitis during active and quiescent disease. (PubMed id 18942752) 1 , 9 Matsuda R....Umemura S. (2009) Osteoblasts derived from osteophytes produce interleu kin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis. (PubMed id 19333684) 1 , 9 Sakao K....Kubo T. (2009) Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signalin g pathways. (PubMed id 19608729) 1 , 9 Wanninger J....Buechler C. (2009) Tristetraprolin regulates IL-8 mRNA stability in cyst ic fibrosis lung epithelial cells. (PubMed id 19363120) 1 , 9 Balakathiresan N.S....Biswas R. (2009) Regulation of chemokine gene expression by hypoxia vi a cooperative activation of NF-kappaB and histone deacetylase. (PubMed id 19446037) 1 , 9 Safronova O....Morita I. (2009) [Acute inflammation phase reactants and interleukin-8 in myocardial infarction] (PubMed id 19514335) 1 , 9 Zorin N.A....Riabicheva T.G. (2009) Serum interleukin-8 levels are elevated in patients with ovarian endometrioma. (PubMed id 18635170) 1 , 9 Ohata Y....Terakawa N. (2008) Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. (PubMed id 18676870) 1 , 9 Hsing A.W....Chanock S.J. (2008) Differential signaling mechanisms of HNP-induced IL-8 production in human lung epithelial cells and monocytes. (PubMed id 17786963) 1 , 9 Syeda F....Zhang H. (2008) The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis. (PubMed id 19046427) 1 , 9 Govindaraju V....Martin J.G. (2008) Interleukin promoter polymorphisms and prognosis in colorectal cancer. (PubMed id 18448485) 1 , 9 Wilkening S....Forsti A. (2008) Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. (PubMed id 18307536) 1 , 9 Li M....Yao Q. (2008) Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts. (PubMed id 18501560) 1 , 9 Tong K.M....Tang C.H. (2008) PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. (PubMed id 18854173) 1 , 9 Tanaka Y....Kawabata A. (2008) Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. (PubMed id 18395088) 1 , 9 Subramaniam D....Anant S. (2008) Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells. (PubMed id 18678662) 1 , 9 Snoeks L....Savkovic S.D. (2008) Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway. (PubMed id 18789871) 1 , 9 Wurm S....Buechler C. (2008) Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. (PubMed id 18252714) 1 , 9 Bhattacharyya S....Tobacman J.K. (2008) Modulation of cystic fibrosis lung disease by variants in interleukin-8. (PubMed id 18563170) 1 , 9 Hillian A.D....Drumm M.L. (2008) The local cytokine and chemokine milieu within malignant effusions. (PubMed id 18515987) 1 , 9 Atanackovic D....Bokemeyer C. (2008) Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10. (PubMed id 18054497) 1 , 9 Petit-Bertron A.F....Adib-Conquy M. (2008) Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells. (PubMed id 17854923) 1 , 9 Moriyuki K....Kawabata A. (2008) Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells. (PubMed id 18211687) 1 , 9 Guillot L....Qureshi S.T. (2008) Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis. (PubMed id 19009622) 1 , 9 Corvol H....Clement A. (2008) Osteopontin and interleukin-8 expression is independently associated with prostate cancer recurrence. (PubMed id 18593988) 1 , 9 Caruso D.J....Lokeshwar B.L. (2008) Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes. (PubMed id 18599499) 1 , 9 Gray J.S....Pestka J.J. (2008) Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4. (PubMed id 18031543) 1 , 9 Voelcker V....Simon J. (2008) Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells. (PubMed id 18380907) 1 , 9 Issa R....Mitchell J.A. (2008) Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells. (PubMed id 18487355) 1 , 9 Chmura K....Chan E.D. (2008) IL-8 and p53 are inversely regulated through JNK, p38 and NF-kappaB p65 in HepG2 cells during an inflammatory response. (PubMed id 18607537) 1 , 9 Rasmussen M.K....Gesser B. (2008) Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: Potential mechanism for excessive IL-8 expression. (PubMed id 17936667) 1 , 9 Boncoeur E....Tabary O. (2008) A single nucleotide polymorphism in the matrix metalloproteinase-1 and interleukin-8 gene promoter predicts poor prognosis in tongue cancer. (PubMed id 18276095) 1 , 9 Shimizu Y....Yoshizaki T. (2008) Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling. (PubMed id 17420005) 1 , 9 Muselet-Charlier C....Tabary O. (2007) Interleukin (IL)-12 receptor beta1 codon 378 G homozygote and allele, but not IL-1 (beta-511 promoter, 3953 exon 5, receptor antagonist), IL-2 114, IL-4-590 intron 3, IL-8 3'-UTR 2767, and IL-18 105, are associated with higher susceptibility to leiomyoma. (PubMed id 17222831) 1 , 9 Hsieh Y.Y....Tsai F.J. (2007) Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes. (PubMed id 17444864) 1 , 9 Seno H....Chiba T. (2007) Cytokine genotype and phenotype effects on lung function decline in firefighters. (PubMed id 17351514) 1 , 9 Josyula A.B....Burgess J.L. (2007) Bronchoalveolar cellularity and interleukin-8 levels in measles bronchiolitis obliterans. (PubMed id 17494793) 1 , 9 Koh Y.Y....Kim C.K. (2007) Association between human African trypanosomiasis and the IL6 gene in a Congolese population. (PubMed id 16720107) 1 , 9 Courtin D....Garcia A. (2007) [Association of cytokines genes (ILL, IL1RN, TNF, LTA, IL6, IL8, IL0) polymorphic markers with chronic obstructive pulmonary disease] (PubMed id 17380888) 1 , 9 Danilko K.V....Victorova T.V. (2007) Increased serum levels of CXCL8 chemokine in acute toxoplasmic retinochoroiditis. 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(2007) Bcl10 mediates LPS-induced activation of NF-kappaB and IL-8 in human intestinal epithelial cells. (PubMed id 17540779) 1 , 9 Bhattacharyya S....Tobacman J.K. (2007) Stored packed red blood cell transfusion up-regulates inflammatory gene expression in circulating leukocytes. (PubMed id 17592301) 1 , 9 Escobar G.A....Banerjee A. (2007) Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. (PubMed id 17908769) 1 , 9 Emonts M....Sanders E.A. (2007) L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. (PubMed id 17022986) 1 , 9 Abe Y....Ballantyne C.M. (2007) Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. (PubMed id 17466952) 1 , 9 Verhaeghe C....Bours V. 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(PubMed id 17020928) 1 , 9 Tachado S.D....Koziel H. (2007) Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C. (PubMed id 16491014) 1 , 9 Matsubara M....Hasegawa K. (2006) Genetic variation in IL-8 associated with increased risk and poor prognosis of breast carcinoma. (PubMed id 16698420) 1 , 9 Snoussi K....Chouchane L. (2006) Low-density lipoprotein modified by macrophage-derived lysosomal hydrolases induces expression and secretion of IL-8 via p38 MAPK and NF-kappaB by human monocyte-derived macrophages. (PubMed id 16973972) 1 , 9 Hakala J.K....Pentikainen M.O. (2006) Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. (PubMed id 16541418) 1 , 9 Lu S. and Dong Z. (2006) Insulin-like growth factor-I augments interleukin-8 promoter activity through induction of activator protein-1 complex formation. (PubMed id 16846747) 1 , 9 Kooijman R....Van den Keybus C. (2006) Inflammation-related gene polymorphisms and colorectal adenoma. (PubMed id 16775170) 1 , 9 Gunter M.J....Rothman N. (2006) Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria. (PubMed id 16794530) 1 , 9 Ciszek M....Mucha K. (2006) Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections. (PubMed id 16503988) 1 , 9 Puthothu B....Heinzmann A. (2006) Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure. (PubMed id 16251188) 1 , 9 Dobreva I....Widmann C. 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(2006) Mechanical stretch stimulates interleukin-8 production in endometrial stromal cells: possible implications in endometrium-related events. (PubMed id 15585560) 1 , 9 Harada M....Taketani Y. (2005) Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha. (PubMed id 15828019) 1 , 9 Facchini A....Flamigni F. (2005) Human neutrophils promote angiogenesis by a paracrine feedforward mechanism involving endothelial interleukin-8. (PubMed id 15498828) 1 , 9 Schruefer R....Walzog B. (2005) Autocrine and paracrine regulation of interleukin-8 expression in lung cancer cells. (PubMed id 15746434) 1 , 9 Yao P.L....Yang P.C. (2005) Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. (PubMed id 15564333) 1 , 9 Lappas M....Rice G.E. (2005) Induction of a CXCL8 binding site on endothelial syndecan-3 in rheumatoid synovium. (PubMed id 16052590) 1 , 9 Patterson A.M....Middleton J. (2005) Interleukin-8 in whole blood and clinical status in cystic fibrosis. (PubMed id 15579374) 1 , 9 Schmitt-Grohe S....Zielen S. (2005) Correlation of augmented IL-8 production to premature chronic lung disease: implication of posttranscriptional regulation. (PubMed id 16085794) 1 , 9 Huang H.C....Yang K.D. (2005) MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-kappaB-mediated interleukin-8 transcription in response to cytokines or growth factors. (PubMed id 15615716) 1 , 9 Hoffmann E....Kracht M. (2005) Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production. (PubMed id 15803062) 1 , 9 Williams M.A....Solomkin J.S. (2005) Interleukin-8 induces nuclear transcription factor-kappaB through a TRAF6-dependent pathway. (PubMed id 15591054) 1 , 9 Manna S.K. and Ramesh G.T. (2005) In vivo relationship between collagenase-2 and interleukin-8 but not tumour necrosis factor-alpha in chronic rhinosinusitis with nasal polyposis. (PubMed id 16134994) 1 , 9 Kostamo K....Toskala E. (2005) Neutrophil elastase induces IL-8 synthesis by lung epithelial cells via the mitogen-activated protein kinase pathway. (PubMed id 14730209) 1 , 9 Chen H.C....Kuo H.P. (2004) Cyclic mechanical stretch augments both interleukin-8 and monocyte chemotactic protein-3 production in the cultured human uterine cervical fibroblast cells. (PubMed id 15194816) 1 , 9 Takemura M....Fujii S. (2004) Interleukin (IL)-1 beta in tracheal aspirates from premature infants induces airway epithelial cell IL-8 expression via an NF-kappa B dependent pathway. (PubMed id 15496610) 1 , 9 Shimotake T.K....Hershenson M.B. 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(2011) The role of IL-6, IL-8 and MCP-1 and their promoter p olymorphisms IL-6 -174GC, IL-8 -251AT and MCP-1 -2518AG in the risk of venous t hromboembolism: a case-control study. (PubMed id 21620438) 1 Matos M.F....Morelli V.M. (2011) Constitutive ERK activity induces downregulation of t ristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability i n melanoma cells. (PubMed id 21593445) 1 Bourcier C....PagA"s G. (2011) Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8. (PubMed id 21649887) 1 Carpagnano G.E....Foschino-Barbaro M.P. (2011) Prognostic significance of IL-8-STAT-3 pathway in ast rocytomas: correlation with IL-6, VEGF and microvessel morphometry. (PubMed id 21684758) 1 Piperi C....Korkolopoulou P. (2011) Nebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosis. (PubMed id 21330456) 1 Reeves E.P....McElvaney N.G. (2011) [Relationship between polymorphism of interleukin-8 an d silicosis susceptibility]. (PubMed id 22214159) 1 Sun D....Li C.L. (2011) Steroid-insensitive ERK1/2 activity drives CXCL8 synt hesis and neutrophilia by airway smooth muscle. (PubMed id 21493783) 1 Robins S....Rousseau S. (2011) Mycoplasma pneumoniae induces interleukin-8 productio n via the epidermal growth factor receptor pathway. (PubMed id 21831204) 1 Arae K....Taguchi H. (2011) Interleukin-8 is associated with proliferation, migra tion, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer ce ll line models. (PubMed id 20648559) 1 Ning Y....Lenz H.J. (2011) CXCL8 protects human neurons from amyloid-I^-induced n eurotoxicity: relevance to Alzheimer's disease. (PubMed id 21840299) 1 Ashutosh ....Ghorpade A. (2011) Increases of vitreous monocyte chemotactic protein 1 a nd interleukin 8 levels in patients with concurrent hypertension and diabetic re tinopathy. 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(2011) Increased levels of human neutrophil peptides 1, 2, a nd 3 in peritoneal fluid of patients with endometriosis: association with neutr ophils, T cells and IL-8. (PubMed id 21831449) 1 Milewski A.8....Malejczyk J. (2011) Advanced glycation end products (AGEs) induce apoptos is via a novel pathway: involvement of Ca2+ mediated by interleukin-8 protein. (PubMed id 21862577) 1 Mahali S....Manna S.K. (2011) Interleukin-8 is activated in patients with chronic l iver diseases and associated with hepatic macrophage accumulation in human live r fibrosis. (PubMed id 21731723) 1 Zimmermann H.W....Tacke F. (2011) [Association of IL-8 gene polymorphisms with inflammat ory bowel disease in Chinese patients]. (PubMed id 22093783) 1 Liang W.D....Bi Y.T. (2011) Association of IL8 -251A/T, IL12B -1188A/C and TNF-I+ -238A/G polymorphisms with Tourette syndrome in a family-based association stud y in a Chinese Han population. (PubMed id 21443923) 1 Liu S....Ma X. (2011) Regulation of the p38 mitogen-activated protein kinas e and dual-specificity phosphatase 1 feedback loop modulates the induction of i nterleukin 6 and 8 in cells infected with coronavirus infectious bronchitis vir us. (PubMed id 21959016) 1 Liao Y....Liu D.X. (2011) Enhanced Ca2+ entry due to Orai1 plasma membrane inser tion increases IL-8 secretion by cystic fibrosis airways. (PubMed id 21873556) 1 Balghi H....Hanrahan J.W. (2011) Human CD4+ FOXP3+ regulatory T cells produce CXCL8 an d recruit neutrophils. (PubMed id 21268001) 1 Himmel M.E....Levings M.K. (2011) Circulating interleukin (IL)-8, IL-2R, IL-12, and IL- 15 levels are independently prognostic in primary myelofibrosis: a comprehensiv e cytokine profiling study. (PubMed id 21300928) 1 Tefferi A....Pardanani A. (2011) Modulation of NK cell autocrine-induced eosinophil ch emotaxis by interleukin-15 and vitamin D(3): a possible NK-eosinophil crosstalk via IL-8 in the pathophysiology of allergic rhinitis. 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(2011) Sulforaphane inhibits de novo synthesis of IL-8 and M CP-1 in human epithelial cells generated by cigarette smoke extract. (PubMed id 21401388) 1 Starrett W. and Blake D.J. (2011) Elevated miR-155 promotes inflammation in cystic fibr osis by driving hyperexpression of interleukin-8. (PubMed id 21282106) 1 Bhattacharyya S....Biswas R. (2011) Knockdown of CypA inhibits interleukin-8 (IL-8) and I L-8-mediated proliferation and tumor growth of glioblastoma cells through down- regulated NF-I_B. (PubMed id 20454998) 1 Sun S....Chiu R. (2011) Control of cell migration and inflammatory mediators p roduction by CORM-2 in osteoarthritic synoviocytes. (PubMed id 21961038) 1 Garcia-Arnandis I....Alcaraz M.J. (2011) Interactions of interleukin-8 with the human chemokin e receptor CXCR1 in phospholipid bilayers by NMR spectroscopy. (PubMed id 22019593) 1 Park S.H....Opella S.J. 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(2011) MAPK signaling pathways regulate IL-8 mRNA stability and IL-8 protein expression in cystic fibrosis lung epithelial cell lines. (PubMed id 20952496) 1 Bhattacharyya S....Biswas R. (2011) ERI^ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. (PubMed id 21266854) 1 Chen Y....Shao Z.M. (2011) Semaphorin 7A on keratinocytes induces interleukin-8 production by monocytes. (PubMed id 21524887) 1 Kamata M....Sato S. (2011) P. aeruginosa drives CXCL8 synthesis via redundant to ll-like receptors and NADPH oxidase in CFTRa88F508 airway epithelial cells. (PubMed id 21176887) 1 Roussel L....Rousseau S. (2011) Low molecular weight hyaluronan, via AP-1 and NF-kB si gnalling, induces IL-8 in transformed bronchial epithelial cells. (PubMed id 21989944) 1 Ochoa C....Quinn D. (2011) Oct4-related cytokine effects regulate tumorigenic pr operties of colorectal cancer cells. (PubMed id 22037460) 1 Chang C.J....Lan Y.T. 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(2011) [Influence of genetic mutations on clinical presentat ion of subretinal neovascularization. Report 1: The impact of CFH and IL-8 gene s polymorphism]. (PubMed id 21882633) 1 Budzinskaia M.V....Galoian N.S. (2011) The IL-8-regulated chemokine receptor CXCR7 stimulate s EGFR signaling to promote prostate cancer growth. (PubMed id 21398406) 1 Singh R.K. and Lokeshwar B.L. (2011) Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcrip tion. (PubMed id 20886283) 1 Ritter B....Nourbakhsh M. (2011) CC and CXC chemokines induce airway smooth muscle pro liferation and survival. (PubMed id 21368236) 1 Halwani R....Hamid Q. (2011) Interleukin(IL)-4 promotion of CXCL-8 gene transcript ion is mediated by ERK1/2 pathway in human pulmonary artery endothelial cells. (PubMed id 21645924) 1 Yang D.F....Lavoie J.P. 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(2010) Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocy te chemotactic protein-1 and nitric oxide are major regulatory factors. (PubMed id 20102417) 1 Kumar R....Salotra P. (2010) A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiat ion in rectal cancer. (PubMed id 20644561) 1 Ho-Pun-Cheung A....Lopez-Crapez E. (2010) Integrin-mediated inhibition of interleukin-8 secreti on from human neutrophils by collagen type I. (PubMed id 19995941) 1 Quan W.Y....Nishida T. (2010) TGFI^1 induces IL-6 and inhibits IL-8 release in human bronchial epithelial cells: the role of Smad2/3. (PubMed id 20607798) 1 Ge Q....Burgess J.K. (2010) Cleavage of the NF-{kappa}B family protein p65/RelA b y the chlamydial protease-like activity factor (CPAF) impairs proinflammatory s ignaling in cells infected with Chlamydiae. 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(2010) Role of inflammatory cells, cytokines and matrix meta lloproteinases in neutrophil-mediated skin diseases. (PubMed id 20636397) 1 Marzano A.V....Crosti C. (2010) Cell-bound IL-8 increases in bronchial epithelial cel ls after arylsulfatase B silencing due to sequestration with chondroitin-4-sulf ate. (PubMed id 19346317) 1 Bhattacharyya S....Tobacman J.K. (2010) A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868) 1 Romero R....Menon R. (2010) Pneumococcal proteins PspA and PspC induce CXCL8 prod uction in human neutrophils: implications in pneumococcal infections. (PubMed id 20670689) 1 Cao J....Zhang X. (2010) Phospholipase D signaling pathway is involved in lung cancer-derived IL-8 increased osteoclastogenesis. (PubMed id 20106902) 1 Hsu Y.L....Kuo P.L. (2010) Differential transcriptional regulation of IL-8 expre ssion by human airway epithelial cells exposed to diesel exhaust particles. (PubMed id 19914270) 1 Tal T.L....Samet J.M. (2010) Prenatal maternal stress and cord blood innate and ad aptive cytokine responses in an inner-city cohort. (PubMed id 20194818) 1 Wright R.J....Gern J.E. (2010) Genetic variants in inflammation-related genes are as sociated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626) 1 Hildebrandt M.A....Wu X. (2010) IL8 and CXCL13 are potent chemokines for the recruitm ent of human neural precursor cells across brain endothelial cells. (PubMed id 20400187) 1 Weiss N....Cazaubon S. (2010) Associations of plasma IL-8 levels with Helicobacter pylori seropositivity, gastric atrophy, and IL-8 T-251A genotypes. (PubMed id 19719901) 1 Naito M....Hamajima N. 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(2010) IL-8, IL-12 and IL-10 cytokines generation by neutrop hils, fibroblasts and neutrophils- fibroblasts interaction in psoriasis. (PubMed id 20934961) 1 Glowacka E....Zalewska A. (2010) Selective upregulation of interleukin-8 by human rhab domyosarcomas in response to hypoxia: therapeutic implications. (PubMed id 19588509) 1 Wysoczynski M....Ratajczak M.Z. (2010) I+-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8. (PubMed id 21060150) 1 Bergin D.A....McElvaney N.G. (2010) Genetic variations in angiogenesis pathway genes asso ciated with clinical outcome in localized gastric adenocarcinoma. (PubMed id 19622587) 1 Lurje G....Lenz H.J. (2010) The CXC chemokine-degrading protease SpyCep of Strept ococcus pyogenes promotes its uptake into endothelial cells. (PubMed id 20562101) 1 Kaur S.J....Talay S.R. (2010) Gingko biloba extract reduces VEGF and CXCL-8/IL-8 le vels in keratinocytes with cumulative effect with epigallocatechin-3-gallate. (PubMed id 19597830) 1 Trompezinski S....Viac J. (2010) Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients. (PubMed id 20217044) 1 Gu W....Jiang J.X. (2010) Immunological parameters, including CXCL8 (IL-8) char acterize cerebro- and cardiovascular events in patients with peripheral artery diseases. (PubMed id 20384872) 1 Szomjak E....Szodoray P. (2010) Stress effects on FosB- and interleukin-8 (IL8)-drive n ovarian cancer growth and metastasis. (PubMed id 20826776) 1 Shahzad M.M....Sood A.K. (2010) Involvement of p120 in LPS-induced NF-kappaB activati on and IL-8 production in human bronchial epithelial cells. (PubMed id 20172018) 1 Wang M....Wu R. (2010) Polymorphisms in innate immunity genes and patients r esponse to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178) 1 Segat L....Crovella S. (2010) The human ovarian follicular fluid level of interleuk in-8 is associated with follicular size and patient age. (PubMed id 19285667) 1 Malizia B.A....Usheva A. (2010) The association of innate immune response gene polymo rphisms and puerperal group A streptococcal sepsis. (PubMed id 20207250) 1 Davis S.M....Silver R.M. (2010) Association of interleukin-8 gene polymorphisms and h aplotypes with oral lichen planus in a Chinese population. (PubMed id 19842025) 1 Dan H....Zeng X. (2010) High cerebrospinal fluid antioxidants and interleukin 8 are protective of hypoxic brain damage in newborns. (PubMed id 20166885) 1 Hussein M.H....Togari H. (2010) HIV-1 infection inhibits cytokine production in human thymic macrophages. (PubMed id 20817073) 1 Rozmyslowicz T....Gaulton G.N. (2010) Association of haplotypes of inflammation-related gen es with gastric preneoplastic lesions in African Americans and Caucasians. (PubMed id 20473875) 1 Zabaleta J....Ochoa A.C. 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(2010) Transient receptor potential melastatin 2 is required for lipopolysaccharide-induced cytokine production in human monocytes. (PubMed id 20107186) 1 Wehrhahn J....Hauschildt S. (2010) HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-I_B pathway and can be silenced by gp120- specific siRNA. (PubMed id 21190575) 1 Shah A. and Kumar A. (2010) Thromboxane A(2) increases endothelial permeability t hrough upregulation of interleukin-8. (PubMed id 20510674) 1 Kim S.R....Bae M.K. (2010) Peroxisome proliferator-activated receptor {delta} ac tivators induce IL-8 expression in nonstimulated endothelial cells in a transcr iptional and posttranscriptional manner. (PubMed id 20592029) 1 Meissner M....Kaufmann R. (2010) Cardiovascular disease in kidney transplant recipient s: the prognostic value of inflammatory cytokine genotypes. (PubMed id 20061995) 1 La Manna G....Stefoni S. (2010) Common polymorphisms in ITGA2, PON1 and THBS2 are ass ociated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PubMed id 20485444) 1 Wang Y....Huang W. (2010) Interleukin 10 polymorphisms differentially influence the risk of gastric cancer in East Asians and Caucasians. (PubMed id 20363151) 1 Won H.H....Lee K.A. (2010) Regulation of IL-8 production by complement-activated product, C5a, in vitro and in vivo during sepsis. (PubMed id 20591742) 1 Wang L....Li Y. (2010) HIF-1alpha mediates the induction of IL-8 and VEGF ex pression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-l ike behaviour. (PubMed id 20039880) 1 Cane G....Vouret-Craviari V. (2010) Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer. (PubMed id 20711410) 1 Gannon P.O....Mes-Masson A.M. 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(2009) Influence of cytokine gene polymorphisms on prostate- specific antigen recurrence in prostate cancer after radical prostatectomy. (PubMed id 19996656) 1 Lin H.C....Huang S.P. (2009) Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells. (PubMed id 18657231) 1 Smadja D.M....Gaussem P. (2009) Prostaglandin F(2alpha)-F-prostanoid receptor regulat es CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcine urin-NFAT pathway. (PubMed id 19819266) 1 Sales K.J....Jabbour H.N. (2009) Sterile trauma to normal human dermis invariably indu ces IL1beta, IL6 and IL8 in an innate response to 'danger'. (PubMed id 19734969) 1 SjAPgren F. and Anderson C. (2009) Role of inflammation gene polymorphisms on pain sever ity in lung cancer patients. (PubMed id 19773451) 1 Reyes-Gibby C.C....Shete S. (2009) Angiotensin type 1 receptor expression and interleuki n-8 production in polymorphonuclear leukocytes of patients with peripheral arte rial disease. (PubMed id 19755917) 1 Marino F....Cosentino M. (2009) Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways. (PubMed id 19726162) 1 Grange P.A....Dupin N. (2009) Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. (PubMed id 19176759) 1 Hao Q....Tang H. (2009) Physiologic cold shock increases adherence of Moraxel la catarrhalis to and secretion of interleukin 8 in human upper respiratory tra ct epithelial cells. (PubMed id 19835476) 1 Spaniol V....Aebi C. (2009) HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr). (PubMed id 19275586) 1 Majumder B....Ayyavoo V. (2009) Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis. (PubMed id 19364277) 1 Kim Y.J....Scarel-Caminaga R.M. (2009) Cellular interaction regulates interleukin-8 secretion by granulosa-lutein cells and monocytes/macrophages. (PubMed id 19086996) 1 PoA8eA8 A....FedorcsA!k P. (2009) Cytokine and cytokine receptor single-nucleotide poly morphisms predict risk for non-small cell lung cancer among women. (PubMed id 19505916) 1 Van Dyke A.L....Schwartz A.G. (2009) Interleukin-8 T-251A polymorphism was associated with positive anti-p53 antibodies in Uzbekistan population. (PubMed id 19994728) 1 Okada R....Hamajima N. (2009) Difference in the regulation of IL-8 expression induc ed by uropathogenic E. coli between two kinds of urinary tract epithelial cells . (PubMed id 19799797) 1 Tsai K.W....Chen C.N. (2009) Neurotensin signaling induces intracellular alkaliniz ation and interleukin-8 expression in human pancreatic cancer cells. (PubMed id 19393580) 1 Olszewski U. and Hamilton G. (2009) Induced interleukin-8 expression in gliomas by tumor- associated macrophages. (PubMed id 19156359) 1 Hong T.M....Tsai J.C. (2009) Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370) 1 Dagle J.M....Murray J.C. (2009) Human intestinal intraepithelial lymphocytes and epithelial cells coinduce interleukin-8 production through the CD2-CD58 interaction. (PubMed id 19109405) 1 Ebert E.C....Praveen R. (2009) Airway inflammation and upregulation of beta2 Mac-1 i ntegrin expression on circulating leukocytes of female ragpickers in India. (PubMed id 19372628) 1 Ray M.R....Lahiri T. (2009) Polymorphism of IL-8 in 251 Allele and Gastric Cancer Susceptibility: A Meta-Analysis. (PubMed id 19777350) 1 Wang J....He Q. 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(2009) Mechanical stretch enhances IL-8 production in pulmon ary microvascular endothelial cells. (PubMed id 19747898) 1 Iwaki M....Hasegawa Y. (2009) The UDP-glucose receptor P2RY14 triggers innate mucos al immunity in the female reproductive tract by inducing IL-8. (PubMed id 19454705) 1 Arase T....Maruyama T. (2009) Circulating IL-8 levels in heart failure patients wit h and without metabolic syndrome. (PubMed id 19410569) 1 Shin M.J....Kang S.M. (2009) Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923) 1 Siezen C.L....Janssen R. (2009) Pseudomonas aeruginosa induces interleukin-8 (IL-8) gene expression in human conjunctiva through the recruitment of both RelA and CCAAT/enhancer-binding protein beta to the IL-8 promoter. (PubMed id 19064995) 1 Venza I....Teti D. (2009) Leptin enhances synthesis of proinflammatory mediator s in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2 , IL-6, and IL-8 production. (PubMed id 19688109) 1 Vuolteenaho K....Moilanen E. (2009) Peripheral cytokines profile in Parkinson's disease. (PubMed id 18678243) 1 Reale M....Onofrj M. (2009) CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. (PubMed id 19112107) 1 Martin D....Gutkind J.S. (2009) Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. (PubMed id 19170075) 1 Mizutani K....Pienta K.J. (2009) Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk. (PubMed id 19246914) 1 Li K....Yao L. (2009) Cytokines derived from cultured skeletal muscle cells after mechanical strain promote neutrophil chemotaxis in vitro. (PubMed id 18974369) 1 Peterson J.M. and Pizza F.X. (2009) Sevoflurane and isoflurane decrease TNF-alpha-induced gene expression in human monocytic THP-1 cells: potential role of intracellular IkappaBalpha regulation. (PubMed id 19360326) 1 Boost K.A....Zwissler B. (2009) Tumor-derived CCL-2 and CXCL-8 as possible prognostic markers of breast cancer: correlation with estrogen and progestrone receptor p henotyping. (PubMed id 22059352) 1 Ghoneim H.M....Demian S.R. (2009) Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans. (PubMed id 19053024) 1 Staiger H....HAoring H.U. (2009) Structure-function relationship of Vpr: biological imp lications. (PubMed id 19275588) 1 Morellet N....Bouaziz S. (2009) Relaxin stimulates interleukin-6 and interleukin-8 se cretion from the extraplacental chorionic cytotrophoblast. (PubMed id 19467703) 1 Bryant-Greenwood G.D....Novy M.J. (2009) Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121) 1 Talmud P.J.... . (2009) Innate immunity in ocular Chlamydia trachomatis infec tion: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarri ng in Gambians. (PubMed id 20015396) 1 Natividad A....Bailey R. (2009) MicroRNA 132 regulates nutritional stress-induced che mokine production through repression of SirT1. (PubMed id 19819989) 1 Strum J.C....Waters K.M. (2009) Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. (PubMed id 19359602) 1 Yuan L....Oettgen P. (2009) Differential activation and regulation of CXCR1 and C XCR2 by CXCL8 monomer and dimer. (PubMed id 19667085) 1 Nasser M.W....Richardson R.M. (2009) [Combined effect of high mobile group box-1 protein a nd lipopolysaccharide on release of cytokines from human HepG2 cells]. (PubMed id 19751561) 1 Liu Z.F....Su L. (2009) Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabete s mellitus. (PubMed id 19773182) 1 Van Sickle B.J....Spagnoli A. (2009) Racial disparity in pathophysiologic pathways of pret erm birth based on genetic variants. (PubMed id 19527514) 1 Menon R....Thorsen P. (2009) Common Variants in Immune and DNA Repair Genes and Risk for Human Papillomavirus Persistence and Progression to Cervical Cancer. (PubMed id 19012493) 1 Wang S.S....Hildesheim A. (2009) Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors. (PubMed id 18800145) 1 Negaard H.F....Iversen P.O. (2009) The 15(S)-hydroxyeicosatetraenoic acid-induced angiog enesis requires Janus kinase 2-signal transducer and activator of transcription -5B-dependent expression of interleukin-8. (PubMed id 19349617) 1 Cheranov S.Y....Rao G.N. (2009) Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians. (PubMed id 19357773) 1 Ahluwalia T.S....Singal P.K. (2009) A gene-based risk score for lung cancer susceptibilit y in smokers and ex-smokers. (PubMed id 19789190) 1 Young R.P....Gamble G.D. (2009) Serum interleukin-6 and interleukin-8 are early bioma rkers of acute kidney injury and predict prolonged mechanical ventilation in ch ildren undergoing cardiac surgery: a case-control study. (PubMed id 19570208) 1 Liu K.D....Faubel S. (2009) Cellular senescence and inflammation: a noteworthy li nk. (PubMed id 19325234) 1 Tsirpanlis G. (2009) IL-8 regulates mucin gene expression at the posttrans criptional level in lung epithelial cells. (PubMed id 19596978) 1 Bautista M.V....Rose M.C. (2009) HIF-1 induction attenuates Nrf2-dependent IL-8 expres sion in human endothelial cells. (PubMed id 19254160) 1 Loboda A....Dulak J. (2009) Proinflammatory tissue response and recovery of adipo kines during 4 days of subcutaneous large-pore microdialysis. (PubMed id 19328242) 1 Clausen T.S....Stallknecht B. (2009) Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. (PubMed id 19805069) 1 Orjalo A.V....Campisi J. (2009) Concentrated ambient ultrafine particle exposure indu ces cardiac changes in young healthy volunteers. (PubMed id 19234105) 1 Samet J.M....Devlin R.B. (2009) The IL-8 production by Streptococcal pyrogenic exotox in B. (PubMed id 19855073) 1 Chang C.W....Lin M.T. (2009) Modulation of expression of IL-8 gene in bronchial ep ithelial cells by 5-methoxypsoralen. (PubMed id 19720161) 1 Nicolis E....Cabrini G. (2009) The genomic basis of cerebral palsy: a HuGE systematic literature review. (PubMed id 19238444) 1 O'Callaghan M.E....Dekker G. (2009) CHFR, a potential tumor suppressor, downregulates int erleukin-8 through the inhibition of NF-kappaB. (PubMed id 19448676) 1 Kashima L....Tokino T. (2009) Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: Enhanced elimination of the infection during disease progression? (PubMed id 19427781) 1 Gao L....Brenner H. (2009) Interleukin 8 and cardiovascular disease. (PubMed id 19617600) 1 Apostolakis S....Spandidos D.A. (2009) CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. (PubMed id 19035451) 1 Matsuo Y....Guha S. (2009) Polymorphisms in inflammation genes, tobacco smoke an d furred pets and wheeze in children. (PubMed id 19674346) 1 SA...Raaschou-Nielsen O. (2009) Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540) 1 Rajaraman P....Chanock S.J. (2009) Enterohemorrhagic Escherichia coli suppresses inflamm atory response to cytokines and its own toxin. (PubMed id 19556613) 1 Bellmeyer A....Hecht G. (2009) Molecular requirements for sorting of the chemokine i nterleukin-8/CXCL8 to endothelial Weibel-Palade bodies. (PubMed id 19578117) 1 Hol J....OynebrAYten I. (2009) Monocyte chemoattractant protein-1 plays a dominant r ole in the chronic inflammation observed in Alzheimer's disease. (PubMed id 18637012) 1 Sokolova A....Shepherd C.E. (2009) Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma. (PubMed id 19066394) 1 Colt J.S....Wang S.S. (2009) Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975) 1 McGeachie M....Ramoni M.F. (2009) Developmental changes in circulating IL-8/CXCL8 isofo rms in neonates. (PubMed id 19232500) 1 Maheshwari A....Ohls R.K. (2009) Common genetic variants in candidate genes and risk o f familial lymphoid malignancies. (PubMed id 19573080) 1 Liang X.S....Goldin L.R. (2009) Identification of candidate genes for susceptibility to reactive arthritis. (PubMed id 19506876) 1 Rihl M....Kuipers J.G. (2009) Association studies of interleukin-8 gene in Graves' disease and Graves' ophthalmopathy. (PubMed id 19816813) 1 Gu L.Q....Ning G. (2009) Inhibitory effects of flavonoids on TNF-alpha-induced IL-8 gene expression in HEK 293 cells. (PubMed id 19470239) 1 Lee S....Kwon H.J. (2009) Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model. (PubMed id 19021203) 1 Schauer I.G....Rowley D.R. (2009) Epicatechin suppresses IL-6, IL-8 and enhances IL-10 production with NF-kappaB nuclear translocation in whole blood stimulated syste m. (PubMed id 19300393) 1 Al-Hanbali M....Matalka K.Z. (2009) Structural basis for differential binding of the inte rleukin-8 monomer and dimer to the CXCR1 N-domain: role of coupled interactions and dynamics. (PubMed id 19681642) 1 Ravindran A....Rajarathnam K. (2009) The angiogenic effect of probiotic Bacillus polyferme nticus on human intestinal microvascular endothelial cells is mediated by IL-8. (PubMed id 20501448) 1 Im E....Rhee S.H. (2009) Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function. (PubMed id 19339032) 1 Cochrane A....Frappier L. (2009) The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ. (PubMed id 18850010) 1 GAPransson M....Aman P. (2009) Elevated tear interleukin-6 and interleukin-8 levels in patients with conjunctivochalasis. (PubMed id 19158563) 1 Erdogan-Poyraz C....Orhan M. (2009) Hepatocyte growth factor induces hypoxia-related inte rleukin-8 expression in lung adenocarcinoma cells. (PubMed id 19184985) 1 Chiang Y.Y. (2009) Human carotid plaque calcification and vulnerability. Relationship between degree of plaque calcification, fibrous cap inflammatory gene expression and symptomatology. (PubMed id 19136823) 1 Wahlgren C.M....Bassiouny H.S. (2009) Gene expression polymorphisms of interleukins-1beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma. (PubMed id 18273643) 1 Vairaktaris E....Patsouris E. (2008) A systematic review of meta-analyses on gene polymorp hisms and gastric cancer risk. (PubMed id 19506726) 1 Gianfagna F....Boccia S. (2008) Inflammation at birth is associated with subnormal development in very preterm infants. (PubMed id 18391842) 1 Hansen-Pupp I....Ley D. (2008) Interleukin-8 production from human umbilical vein endothelial cells during brief hyperglycemia: the effect of tumor necrotic factor-alpha. (PubMed id 17707405) 1 Kinoshita K....Moriya T. (2008) Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885) 1 Enjuanes A....Campo E. (2008) Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction. (PubMed id 18644894) 1 Nakao S....Takeichi M. (2008) Identification of patients with chronic obstructive p ulmonary disease (COPD) by measurement of plasma biomarkers. (PubMed id 20298300) 1 Shaker S.B....Dirksen A. (2008) Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease. (PubMed id 18665932) 1 Kim N....Song I.S. (2008) IL-1beta and IL-8, matrix metalloproteinase 3, and pepsinogen secretion before and after H. pylori eradication in gastroduodenal phenotypes. (PubMed id 18609140) 1 Won Chang Y....Chang R. (2008) Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function. (PubMed id 18536738) 1 Sorrentino R....Mitchell J.A. (2008) Genetic polymorphism of MCP-1-2518, IL-8-251 and susceptibility to acute pancreatitis: A pilot study in population of Suzhou, China. (PubMed id 18837094) 1 Chen W.C. and Nie J.S. (2008) AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva. (PubMed id 18650551) 1 Palanisamy V....Wong D.T. (2008) Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kappaB and JNK/AP-1 pathways. (PubMed id 18322253) 1 Scupoli M.T....Pizzolo G. (2008) Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling. (PubMed id 18283335) 1 Warner K.A....Nor J.E. (2008) Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST). (PubMed id 18628242) 1 Crusius J.B....Gonzalez C.A. (2008) Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization. (PubMed id 18249366) 1 Morelli S.S....Noyes N. (2008) Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. (PubMed id 18549840) 1 Enquobahrie D.A....Psaty B.M. (2008) [Effects of secretory leukocyte protease inhibitor on expression of inflammation mediators in normal human bronchial epithelial cell s induced by cigarette smoke extract] (PubMed id 18953959) 1 Qu M.Y....Gu Q.H. (2008) CD40-CD40 ligand interactions in human microglia induc e CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1 /2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator p rotein-1 (AP-1). (PubMed id 17918746) 1 D'Aversa T.G....Berman J.W. (2008) Campylobacter jejuni invade chicken LMH cells inefficiently and stimulate differential expression of the chicken CXCLi1 and CXCLi2 cytokines. (PubMed id 19047751) 1 Larson C.L....Konkel M.E. (2008) Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study. (PubMed id 18992148) 1 KA1ry S....BAczieau S. (2008) Association between a pro-inflammatory genetic profile and the risk of chronic atrophic gastritis among older adults from Germany. (PubMed id 19013788) 1 Gao L....Brenner H. (2008) The interleukin-8-251*T/*A polymorphism is not associated with risk for gastric carcinoma development in a Portuguese population. (PubMed id 18090907) 1 Canedo P....Machado J.C. (2008) Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748) 1 Velez D.R....Menon R. (2008) Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism. (PubMed id 18424663) 1 Burke S.M....Marshall J.S. (2008) The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription. (PubMed id 18226242) 1 Vardabasso C.... Giacca M. (2008) The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils. (PubMed id 19086264) 1 Chakrabarti S. and Patel K.D. (2008) Live and ultraviolet-inactivated Lactobacillus rhamnosus GG decrease flagellin-induced interleukin-8 production in Caco-2 cells. (PubMed id 18936229) 1 Lopez M....Neu J. (2008) Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029) 1 Luttrell L.M. (2008) Urinary interleukin-8 in acute pyelonephritis of chil dren: a before-after study. (PubMed id 19377236) 1 Mohkam M....Abdollah Gorgi F. (2008) Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements. (PubMed id 18691435) 1 Jiang W....Yang B. (2008) Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. (PubMed id 18086816) 1 Cheng W....Zhong G. (2008) A pro-inflammatory genotype predisposes to Barrett's esophagus. (PubMed id 18192685) 1 Moons L.M....Siersema P.D. (2008) Association of specific haplotype of TNFalpha with Helicobacter pylori-mediated duodenal ulcer in eastern Indian population. (PubMed id 19147919) 1 Chakravorty M....Roychoudhury S. (2008) IFN-beta-mediated inhibition of IL-8 expression requires the ISGF3 components Stat1, Stat2, and IRF-9. (PubMed id 18370868) 1 Laver T....Benveniste E.N. (2008) Tight junction regulation by morphine and HIV-1 tat mo dulates blood-brain barrier permeability. (PubMed id 18574677) 1 Mahajan S.D....Schwartz S.A. (2008) The role of portal vein clamping for cytokine release and neutrophils activity during liver resection and transplant. (PubMed id 19338485) 1 Studzinski A....Juettner B. (2008) Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach. (PubMed id 18284424) 1 Infante J....Combarros O. (2008) Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms. (PubMed id 18184679) 1 Slevogt H....N'Guessan P.D. (2008) Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680) 1 Hosgood H.D....Lan Q. (2008) Necrotic foci, elevated chemokines and infiltrating neutrophils in the liver of glycogen storage disease type Ia. (PubMed id 18191274) 1 Kim S.Y....Chou J.Y. (2008) Lactobacilli inhibit interleukin-8 production induced by Helicobacter pylori lipopolysaccharide-activated Toll-like receptor 4. (PubMed id 18763295) 1 Zhou C....Ma H.S. (2008) CD36 is significantly correlated with adipophilin in human carotid lesions and inversely correlated with plasma ApoAI. (PubMed id 18827892) 1 Collot-Teixeira S....McGregor J.L. (2008) Reactive oxygen species and chemokines: are they elevated in the esophageal mucosa of children with gastroesophageal reflux disease? (PubMed id 18506929) 1 Tutar E....Pehlivanoglu E. (2008) Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration. (PubMed id 18310311) 1 Goverdhan S.V....Lotery A.J. (2008) Interleukin-10 is associated with resistance to febrile seizures: Genetic association and experimental animal studies. (PubMed id 19055487) 1 Ishizaki Y....Hara T. (2008) Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression. (PubMed id 18628251) 1 Cacev T....Kapitanovic S. (2008) IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. (PubMed id 18566434) 1 Skov L....van de Winkel J.G. (2008) Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. (PubMed id 18258920) 1 Bezzerri V....Cabrini G. (2008) Interleukin gene polymorphisms in age-related macular degeneration. (PubMed id 18235016) 1 Tsai Y.Y....Tseng S.H. (2008) Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis. (PubMed id 18662984) 1 Sai J....Richmond A. (2008) Interleukin 8 and susceptibility to coronary artery disease: a population genetics perspective. (PubMed id 18385984) 1 Vogiatzi K....Spandidos D.A. (2008) Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. (PubMed id 18467491) 1 Wu K....Pestell R.G. (2008) Source of inflammatory markers in patients with atrial fibrillation. (PubMed id 18523031) 1 Liuba I....Walfridsson H. (2008) Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events. (PubMed id 18469140) 1 Gouwy M....Van Damme J. (2008) Immune mediators in idiopathic nephrotic syndrome: evidence for a relation between interleukin 8 and proteinuria. (PubMed id 18679168) 1 Souto M.F....SimA/es E Silva A.C. (2008) The Interleukin-8-251 A Allele is Associated With Increased Risk of Noncardia Gastric Adenocarcinoma in Helicobacter pylori-infected Koreans. (PubMed id 18542040) 1 Ye B.D....Song I.S. (2008) [Effect of Zn2+ on level of IL-8 and TNF-alpha mRNA a nd protein expressed of human II alveolar epithelial cells] (PubMed id 18646527) 1 Zhang Q....Shi S. (2008) Relationships between Helicobacter pylori infection status, endoscopic, histopathological findings, and cytokine production in the duodenum of Crohn's disease patients. (PubMed id 19120897) 1 Ando T....Goto H. (2008) Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis. (PubMed id 18416756) 1 de Jongh C.M....Kezic S. (2008) Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. (PubMed id 18571457) 1 Sadik C.D....Muhl H. (2008) The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care. (PubMed id 18990769) 1 Reyes-Gibby C.C....Bruera E. (2008) Chronic inflammation and mortality in haemodialysis: effect of different renal replacement therapies. Results from the RISCAVID study. (PubMed id 18305316) 1 Panichi V....Palla R. (2008) Reference gene selection for real-time polymerase chain reaction in human lung cells subjected to cyclic mechanical strain. (PubMed id 18785913) 1 Pinhu L....Griffiths M.J. (2008) Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells. (PubMed id 18234802) 1 Hsu M....Chang Y. (2008) The altered expression of inflammation-related molecules and secretion of IL-6 and IL-8 by HUVEC from newborns with maternal inactive systemic lupus erythematosus is modified by estrogens. (PubMed id 19029276) 1 Rodriguez E....MontaA+o L.F. (2008) Association of anemia and erythropoiesis stimulating agents with inflammatory biomarkers in chronic kidney disease. (PubMed id 18547996) 1 Keithi-Reddy S.R....Singh A.K. (2008) Translationally regulated C/EBP beta isoform expression upregulates metastatic genes in hormone-independent prostate cancer cells. (PubMed id 18512730) 1 Kim M.H. and Field J. (2008) Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris. (PubMed id 18463682) 1 Nakatsuji T....Huang C.M. (2008) Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335) 1 Velez D.R....Menon R. (2008) Oxidative inactivation of the proteasome in retinal pigment epithelial cells. A potential link between oxidative stress and up-regulation of interleukin-8. (PubMed id 18502748) 1 Fernandes A.F....Shang F. (2008) The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection. (PubMed id 18426885) 1 Buchholz K.R. and Stephens R.S. (2008) Contribution of GM-CSF and IL-8 to the CD44-induced differentiation of acute monoblastic leukemia. (PubMed id 17914409) 1 Delaunay J....Smadja-Joffe F. (2008) Cord blood cytokine levels in neonates born to mothers with prolonged premature rupture of membranes and its relationship with morbidity and mortality. (PubMed id 18299272) 1 Satar M....Cetiner S. (2008) IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa. (PubMed id 17944600) 1 Groux-Degroote S.... Delannoy P. (2008) Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study. (PubMed id 18164040) 1 Vogel U....Tjonneland A. (2008) Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. (PubMed id 18824549) 1 Hartl D....Elias J.A. (2008) [Effect of fibrinogen on the secretion of interleukin -1beta and - 8 by polymorphonuclear leukocytes]. (PubMed id 18380966) 1 Ge S....Meng S. (2008) IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behcet's disease in patients of German or Turkish origin. (PubMed id 19026125) 1 Storz K....Kotter I. (2008) Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. (PubMed id 18633131) 1 Habermann T.M....Cerhan J.R. (2008) Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures. (PubMed id 18441098) 1 Sabnis A.S....Yost G.S. (2008) The protease-activated receptor-3 (PAR-3) can signal autonomously to induce interleukin-8 release. (PubMed id 18264801) 1 Ostrowska E. and Reiser G. (2008) A report of cytokine polymorphisms and COPD risk in Xuan Wei, China. (PubMed id 17681858) 1 Shen M....Lan Q. (2008) The IL-8 protease SpyCEP/ScpC of group A Streptococcu s promotes resistance to neutrophil killing. (PubMed id 18692776) 1 Zinkernagel A.S....Nizet V. (2008) HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity. (PubMed id 18799285) 1 Akeno N....Tomer Y. (2008) The chemokine interleukin-8 and the surface activatio n protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia. (PubMed id 19383348) 1 Hantschel O....Superti-Furga G. (2008) Macrophage migration inhibitory factor and interleukin-8 produced by gastric epithelial cells during Helicobacter pylori exposure induce expression and activation of the epidermal growth factor receptor. (PubMed id 18474653) 1 Beswick E.J. and Reyes V.E. (2008) Angiopoietin-1 promotes endothelial cell proliferation and migration through AP-1-dependent autocrine production of interleukin-8. (PubMed id 18252863) 1 Abdel-Malak N.A....Hussain S.N. (2008) Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer. (PubMed id 18550579) 1 Lurje G....Lenz H.J. (2008) PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway. (PubMed id 18523665) 1 Vij N....Mohan R.R. (2008) [Effect of co-culture of bone marrow mesenchymal stem cells and K562 cells on expression of interleukin 8] (PubMed id 18315921) 1 Wang L.X....Li J.Y. (2008) Association of cytokine gene polymorphisms with rate of decline in lung function. (PubMed id 18545091) 1 Yucesoy B....Burgess J.L. (2008) Leptin receptor-related immune response in colorectal tumors: the role of colonocytes and interleukin-8. (PubMed id 19010917) 1 Abolhassani M....Sobhani I. (2008) Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis. (PubMed id 18780829) 1 Wilson C....Waugh D.J. (2008) Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB. (PubMed id 18074095) 1 Oem J.K....Liu Q. (2008) Protease-activated receptor (PAR)-induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK. (PubMed id 18086557) 1 Ostrowska E. and Reiser G. (2008) Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant. (PubMed id 18025101) 1 Dias I.H....Griffiths H.R. (2008) Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. (PubMed id 18703508) 1 Balloy V....Chignard M. (2008) Candidate genes and cerebral palsy: a population-based study. (PubMed id 18977990) 1 Gibson C.S....Nelson K.B. (2008) Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta. (PubMed id 18617617) 1 Chen S.U....Yang Y.S. (2008) Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758) 1 Lambert N.A. (2008) Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation. (PubMed id 18487223) 1 Seaton A....Waugh D.J. (2008) IL-8 production and AP-1 transactivation induced by UVA in human keratinocytes: roles of D-alpha-tocopherol. (PubMed id 18206243) 1 Wu S....Fimmel S. (2008) unpaired (upd)-3 expression and other immune-related functions are stimulated by interleukin-8 in Drosophila melanogaster SL2 cell line. (PubMed id 18926718) 1 Malagoli D....Ottaviani E. (2008) Pathogenesis of HIV-associated nephropathy. (PubMed id 19013323) 1 Leventhal J.S. and Ross M.J. (2008) Stimulation of the peroxisome proliferator-activated receptor gamma (PPAR gamma) and the expression of selected blood monocyte cytokine genes in diabetic macroangiopathy. (PubMed id 17141246) 1 Adamiec R....Sadakierska-Chudy A. (2007) Identification of the dimerisation interface of human interleukin-8 by IL-8-variants containing the photoactivatable amino acid benzoyl-phenylalanine. (PubMed id 17024463) 1 David R. and Beck-Sickinger A.G. (2007) Cytokine gene polymorphisms in Italian preterm infants: association between interleukin-10 -1082 G/A polymorphism and respiratory distress syndrome. (PubMed id 17314689) 1 Capasso M....Iolascon A. (2007) Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. (PubMed id 17008880) 1 Kang J.S....Lee W.J. (2007) [Meta-analysis on the relationship between IL8-251 gene polymorphism and gastric cancer] (PubMed id 17767856) 1 Lu Y....Xu Y.C. (2007) Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer. (PubMed id 17638896) 1 Araki S....Lokeshwar B.L. (2007) Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. (PubMed id 17061983) 1 Vanaudenaerde B.M....Verleden G.M. (2007) [Genetic polymorphisms of interferon-gamma and interleukin-8 in patients with nasopharyngeal carcinoma] (PubMed id 17953379) 1 Tai S.H....Zhang L. (2007) Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes. (PubMed id 17307204) 1 Vogel U....Tjonneland A. (2007) Intrahepatic interleukin-8 production during disease progression of chronic hepatitis C. (PubMed id 17240051) 1 Tachibana Y....Kaneko S. (2007) Polymorphisms in genes involved in innate immunity predispose toward mycetoma susceptibility. (PubMed id 17709521) 1 van de Sande W.W....van Belkum A. (2007) Effects of transcription factor activator protein-1 on interleukin-8 expression and enteritis in response to Clostridium difficile toxin A. (PubMed id 17639289) 1 Lee J.Y....Kim J.M. (2007) Chronic infections and genetic factors in the development of ischemic stroke. (PubMed id 17802898) 1 Kis Z....Gonczol E. (2007) Expression profiles and pathway analysis in HEK 293 T cells overexpressing HIV-1 Tat and nucleocapsid using cDNA microarray. (PubMed id 18051367) 1 Park S.E....Park J.H. (2007) [Porphyromonas gingivalis vesicle induced cellular in flammatory responses of gingival epithelial cells in vitro] (PubMed id 18070438) 1 Kou Y.R. and Pan Y.P. (2007) Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrhea. (PubMed id 17618838) 1 Jiang Z.D....DuPont H.L. (2007) [Production of proinflammatory cytokines IL-6 and IL-8 by peripheral blood lymphocytes T under influence in vitro of squamous cell carcinoma of the larynx] (PubMed id 18260266) 1 Starska K....Gl/owacka E. (2007) Stimulated production of interleukin-8 covaries with psychosocial risk factors for inflammatory disease among middle-aged community volunteers. (PubMed id 16996240) 1 Marsland A.L....Manuck S.B. (2007) Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival. (PubMed id 17327408) 1 Cerhan J.R....Hartge P. (2007) PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium. (PubMed id 17581194) 1 Rudack C....Sachse F. (2007) Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells. (PubMed id 17203209) 1 Yoshida N....Okanoue T. (2007) Interleukin-8 gene polymorphism -251T>A and Alzheimer's disease. (PubMed id 18057554) 1 Vendramini A.A....Payao S.L. (2007) Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A. (PubMed id 18086782) 1 Reyes-Gibby C.C....Shete S. (2007) Single nucleotide polymorphism and haplotype association of the interleukin-8 gene with nasopharyngeal carcinoma. (PubMed id 17720627) 1 Wei Y.S....Huang W.T. (2007) Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes. (PubMed id 17680645) 1 Joshi-Barve S....McClain C.J. (2007) R5- and X4-HIV-1 use differentially the endometrial epithelial cells HEC-1A to ensure their own spread: implication for mechanisms of sexual transmission. (PubMed id 16934308) 1 Saidi H....Belec L. (2007) Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract. (PubMed id 17356794) 1 Campa D....Canzian F. (2007) Relevance of transforming growth factor-beta1, interleukin-8, and tumor necrosis factor-alpha polymorphisms in patients with chronic pancreatitis. (PubMed id 17400536) 1 Farkas G....Mandi Y. (2007) Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412) 1 Janssen R....Hoebee B. (2007) Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population. (PubMed id 17336597) 1 Watt A.P....Elborn J.S. (2007) Low shear stress-induced interleukin-8 mRNA expression in endothelial cells is mechanotransduced by integrins and the cytoskeleton. (PubMed id 18080864) 1 Cheng M....Chen H. (2007) Use of SiRNA to investigate the role of CagA on H. pylori induced IL-8 production from gastric epithelial cells. (PubMed id 18019737) 1 Yan Y....Cai S. (2007) Expression of toll-like receptors and type 1 interferon specific protein MxA in biliary atresia. (PubMed id 17075576) 1 Huang Y.H....Chuang J.H. (2007) Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue. (PubMed id 17716703) 1 Fox-Canale A.M....Lurain N.S. (2007) Evidence of potential interaction of chemokine genes in susceptibility to systemic sclerosis. (PubMed id 17599774) 1 Lee E.B....Song Y.W. (2007) Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. (PubMed id 17035306) 1 Wagoner J....Polyak S.J. (2007) Porcine adenovirus type 3 E1B large protein downregulates the induction of IL-8. (PubMed id 17565687) 1 Zhou Y....Tikoo S.K. (2007) CXCR1 and CXCR2 activation and regulation. Role of aspartate 199 of the second extracellular loop of CXCR2 in CXCL8-mediated rapid receptor internalization. (PubMed id 17204468) 1 Nasser M.W....Richardson R.M. (2007) Non-T cell activation linker (NTAL) negatively regulates TREM-1/DAP12-induced inflammatory cytokine production in myeloid cells. (PubMed id 17277102) 1 Tessarz A.S....Cerwenka A. (2007) Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-kappaB but involves ERK1/2- and p38 kinase-dependent activation of AP-1. (PubMed id 17471497) 1 Choi E.Y....Jun C.D. (2007) Molecular programming of endothelin-1 in HIV-infected brain: role of Tat in up-regulation of ET-1 and its inhibition by statins. (PubMed id 17197385) 1 Chauhan A....Nath A. (2007) Cytokine gene polymorphisms in Chinese patients with psoriasis. (PubMed id 17388919) 1 Chang Y.T....Tsai S.F. (2007) [Association of interleukin 8 single nucleotide polymorphisms with the susceptibility to respiratory syncytial virus infection] (PubMed id 17456336) 1 Lu A.Z....Zhang X.B. (2007) The interleukin-8 (-251A/T) polymorphism is associated with increased risk for oral squamous cell carcinoma. (PubMed id 17174061) 1 Vairaktaris E....Patsouris E. (2007) Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells. (PubMed id 17538964) 1 Wertheimer A.M....Rosen H.R. (2007) Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. (PubMed id 17416748) 1 Edderkaoui B....Mohan S. (2007) Association of haplotypes of interleukin-10 gene with the risk of cancer. (PubMed id 18457043) 1 Pogoda T.V....Govorun V.M. (2007) Ultraviolet-B irradiation enhances melanoma cell motility via induction of autocrine interleukin 8 secretion. (PubMed id 17620090) 1 Gebhardt C....Simon J.C. (2007) Efficiency of von Willebrand factor-mediated targeting of interleukin-8 into Weibel-Palade bodies. (PubMed id 17883593) 1 Bierings R....van Mourik J.A. (2007) Down-regulation of EDAG expression by retrovirus-mediated small interfering RNA inhibits the growth and IL-8 production of leukemia cells. (PubMed id 17671716) 1 Ling B....Tian Z. (2007) Induction of human monocyte interleukin (IL)-8 by fibrinogen through the toll-like receptor pathway. (PubMed id 17624583) 1 Kuhns D.B....Gallin J.I. (2007) Association of interleukin-8 (IL-8 or CXCL8) -251T/A and CXCR2 +1208C/T gene polymorphisms with breast cancer. (PubMed id 17949231) 1 Kamali-Sarvestani E....Atefi S. (2007) Combined cupric- and cuprous-binding peptides are effective in preventing IL-8 release from endothelial cells and redox reactions. (PubMed id 17433258) 1 Rael L.T....Bar-Or D. (2007) Variation of interleukin 8 -251 A>T polymorphism in worldwide populations and intra-ethnic differences in Japanese populations. (PubMed id 17020755) 1 Fujihara J....Takeshita H. (2007) Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-kappaB and AP-1 in PMA-differentiated THP-1 cells. (PubMed id 17761353) 1 Kang S.S....Han S.H. (2007) Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes. (PubMed id 16959787) 1 Vogel U....Tjonneland A. (2007) The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis. (PubMed id 17848618) 1 Colla S....Giuliani N. (2007) The effect of dermatophytes on cytokine production by human keratinocytes. (PubMed id 17710424) 1 Tani K....Watanabe S. (2007) Estradiol attenuates lipopolysaccharide-induced CXC chemokine ligand 8 production by human peripheral blood monocytes. (PubMed id 17947704) 1 Pioli P.A....Guyre P.M. (2007) Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes. (PubMed id 17850672) 1 Lee H.J....Kim E.C. (2007) Human immunodeficiency virus type 1 efficiently binds to human fetal astrocytes and induces neuroinflammatory responses independent of infection. (PubMed id 17498309) 1 Li J....Volsky D.J. (2007) Regulation of interleukin-8 expression in human prostate cancer cells by insulin-like growth factor-I and inflammatory cytokines. (PubMed id 17513150) 1 Kooijman R....Coppens A. (2007) Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis. (PubMed id 17296422) 1 Artifoni L....Murer L. (2007) IL-8 expression by biliary epithelial cells is associated with neutrophilic infiltration and reactive bile ductules. (PubMed id 17498253) 1 Isse K....Nakanuma Y. (2007) Role of interleukin-8 in the progression of estrogen receptor-negative breast cancer. (PubMed id 18028768) 1 Yao C....Wang S.M. (2007) Cytokine patterns in fibromyalgia and their correlation with clinical manifestations. (PubMed id 17543146) 1 Bazzichi L....Bombardieri S. (2007) Role of human neutrophil peptides in the initial interaction between lung epithelial cells and CD4+ lymphocytes. (PubMed id 17215524) 1 Vaschetto R....Zhang H. (2007) Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer. (PubMed id 17462092) 1 Garza-Gonzalez E....Perez-Perez G.I. (2007) Lack of association of IL8 gene polymorphisms with familial vesico-ureteral reflux. (PubMed id 17211588) 1 Kuroda S. and Puri P. (2007) Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells. (PubMed id 17621625) 1 Yao C....Wang S.M. (2007) Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-ligands. (PubMed id 16293707) 1 Schreiner B....Wiendl H. (2006) Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells. (PubMed id 17078003) 1 Takehara H....Matsuoka T. (2006) Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes. (PubMed id 16939660) 1 Abke S....Buechler C. (2006) IL-6 and IL-8 release is mediated via multiple signaling pathways after stimulating dendritic cells with lysophospholipids. (PubMed id 16769764) 1 Oz-Arslan D....Maghazachi A.A. (2006) Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability. (PubMed id 16824064) 1 Shirai K....Goto H. (2006) Localization of human neutrophil interleukin-8 (CXCL-8) to organelle(s) distinct from the classical granules and secretory vesicles. (PubMed id 16387844) 1 Pellme S....Karlsson A. (2006) Calcium-dependent viral internalization is required for adenovirus type 7 induction of IL-8 protein. (PubMed id 16890267) 1 Wu W....Metcalf J.P. (2006) Increased plasma levels of IL-6 and IL-8 are associated with surgical site infection after pancreaticoduodenectomy. (PubMed id 16552338) 1 Kimura F....Miyazaki M. (2006) Myocardial apoptosis associated with the expression of proinflammatory cytokines during the course of myocardial infarction. (PubMed id 16554734) 1 Akasaka Y....Ishii T. (2006) Histamine and PGE(2) stimulate the production of interleukins -6 and -8 by human articular chondrocytes in vitro. 6. Human and clinical aspects of histamine. (PubMed id 16547804) 1 Tetlow L.C. and Woolley D.E. (2006) Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. (PubMed id 16299055) 1 Schmeck B....Hippenstiel S. (2006) Interleukin-8, ferritin and soluble transferrin receptors in type II diabetes mellitus. (PubMed id 17974147) 1 Abou-Shousha S....Sultan H.K. (2006) [STAT1 antisense oligonucleotides inhibit secretion of TNF-alpha, IL-8 and NO in alveolar macrophages of rats suffering from interstitial pulmonary fibrosis] (PubMed id 16806015) 1 Fan X.M....Wang Z.L. (2006) A common polymorphism in the interleukin 8 gene promoter is associated with Clostridium difficile diarrhea. (PubMed id 16573784) 1 Jiang Z.D....LaRocco M. (2006) Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab. (PubMed id 16788380) 1 Zhang W....Lenz H.J. (2006) Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells. (PubMed id 16552751) 1 Zhao D....Pothoulakis C. (2006) Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway. (PubMed id 16322472) 1 Khine A.A....Zhang H. (2006) HIV tat and neurotoxicity. (PubMed id 16697675) 1 King J.E....Berman J.W. (2006) Phosphorylation of WAVE1 regulates actin polymerizati on and dendritic spine morphology. (PubMed id 16862120) 1 Kim Y....Greengard P. (2006) The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. (PubMed id 16293628) 1 Adam E....Jacquet A. (2006) Intrahepatic gene expression in human alcoholic hepatitis. (PubMed id 16797773) 1 Seth D....Haber P.S. (2006) Regulation of the ASC expression in response to LPS stimulation is related to IL-8 secretion in the human intestinal mucosa. (PubMed id 16777061) 1 Masumoto J....Inohara N. (2006) Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity. (PubMed id 16702372) 1 Brown E.E....Chanock S.J. (2006) Elevated serum levels of proinflammatory cytokines and biomarkers of matrix remodeling in never-treated patients with familial hypercholesterolemia. (PubMed id 16280123) 1 El Messal M....Chapman M.J. (2006) CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner. (PubMed id 16406804) 1 Cohen-Hillel E....Ben-Baruch A. (2006) Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity. (PubMed id 16168518) 1 Hanson J.C....Maher J.J. (2006) Zn2+-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells. (PubMed id 16373669) 1 Kim Y.M....Samet J.M. (2006) H. pylori genotypes and cytokine gene polymorphisms influence the development of gastric intestinal metaplasia in a Chinese population. (PubMed id 16635219) 1 Leung W.K....Sung J.J. (2006) Epithelial cells secrete interleukin-8 in response to adhesion and invasion of diffusely adhering Escherichia coli lacking Afa/Dr genes. (PubMed id 16547413) 1 Meraz I.M....Nishikawa Y. (2006) Polymorphisms in inflammation-related genes and risk of gastric cancer (Finland). (PubMed id 16411061) 1 Kamangar F....Taylor P.R. (2006) Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. (PubMed id 16365152) 1 Tharp W.G....Poznansky M.C. (2006) Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells. (PubMed id 16270354) 1 Secchiero P....Zauli G. (2006) Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. (PubMed id 16394009) 1 Jozsef L....Filep J.G. (2006) The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells. (PubMed id 16990258) 1 Sai J....Richmond A. (2006) The immunoregulatory effects of HIV-1 Nef on dendritic cells and the pathogenesis of AIDS. (PubMed id 17077296) 1 Quaranta M.G....Viora M. (2006) Association of H pylori cagA and vacA genotypes and IL-8 gene polymorphisms with clinical outcome of infection in Iranian patients with gastrointestinal diseases. (PubMed id 16937534) 1 Kamali-Sarvestani E....Saberifiroozi M. (2006) Autocrine role for interleukin-8 in Bartonella henselae-induced angiogenesis. (PubMed id 16926411) 1 McCord A.M....Anderson B.E. (2006) Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. (PubMed id 16620395) 1 Karimi K....Folkerts G. (2006) Genetic variation in interleukin 8 and its receptor genes and its influence on the risk and prognosis of prostate cancer among Finnish men in a large cancer prevention trial. (PubMed id 16679868) 1 Yang H.P....Tangrea J.A. (2006) Chemokine IL-8 and chemokine receptor CXCR3 and CXCR4 gene expression in childhood acute lymphoblastic leukemia at first relapse. (PubMed id 16679918) 1 Wu S....Seeger K. (2006) Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung. (PubMed id 16757060) 1 Hawthorn L....Baumann H. (2006) IL-8/CXC ligand 8 survives neonatal gastric digestion as a result of intrinsic aspartyl proteinase resistance. (PubMed id 15585673) 1 Maheshwari A....Calhoun D.A. (2005) Activation of CD38 by interleukin-8 signaling regulates intracellular Ca2+ level and motility of lymphokine-activated killer cells. (PubMed id 15556942) 1 Rah S.Y....Kim U.H. (2005) Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level. (PubMed id 15531763) 1 Nesmelova I.V....Mayo K.H. (2005) Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy. (PubMed id 16202743) 1 Goepfert A.R....Langer O. (2005) Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer. (PubMed id 16098254) 1 Zhang W....Lenz H.J. (2005) Alive and dead Lactobacillus rhamnosus GG decrease tumor necrosis factor-alpha-induced interleukin-8 production in Caco-2 cells. (PubMed id 15987860) 1 Zhang L....Neu J. (2005) Regulation of matrix metalloproteinase-9 release from IL-8-stimulated human neutrophils. (PubMed id 15831558) 1 Chakrabarti S. and Patel K.D. (2005) Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation. (PubMed id 16240219) 1 Joh T....Itoh M. (2005) Interleukin-8 primes oxidative burst in neutrophil-like HL-60 through changes in cytosolic calcium. (PubMed id 15862344) 1 Brechard S....Tschirhart E.J. (2005) Mycobacterium bovis bacille Calmette Guerin infection of human neutrophils induces CXCL8 secretion by MyD88-dependent TLR2 and TLR4 activation. (PubMed id 15760459) 1 Godaly G. and Young D.B. (2005) Activation of protease-activated receptor 2 stimulates proliferation and interleukin (IL)-6 and IL-8 secretion of endometriotic stromal cells. (PubMed id 16096323) 1 Hirota Y....Taketani Y. (2005) Interleukin 8 mRNA gene expression in peripheral and intra-abdominal neutrophils during human secondary peritonitis. (PubMed id 15897801) 1 Holzer K....Henrich D. (2005) Constitutive IL-8 expression in cancer cells is associated with mutation of p53. (PubMed id 15945132) 1 Hidaka H....Ogawa M. (2005) Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein. (PubMed id 15650393) 1 Valacchi G....van der Vliet A. (2005) Paracrine mitogenic effect of human endothelial progenitor cells: role of interleukin-8. (PubMed id 15805227) 1 He T....Katusic Z.S. (2005) Mycobacterium bovis BCG induces CXC chemokine ligand 8 secretion via the MEK-dependent signal pathway in human epithelial cells. (PubMed id 15894298) 1 Mendez-Samperio P....Miranda E. (2005) Mechanisms of abruption-induced premature rupture of the fetal membranes: thrombin-enhanced interleukin-8 expression in term decidua. (PubMed id 16251427) 1 Lockwood C.J....Schatz F. (2005) Demonstration of an in vivo generated sub-picomolar affinity fully human monoclonal antibody to interleukin-8. (PubMed id 16038881) 1 Rathanaswami P....Babcook J. (2005) Endothelin-1 induces CXCL1 and CXCL8 secretion in human melanoma cells. (PubMed id 16098041) 1 Mangahas C.R....Jamal S. (2005) ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP. (PubMed id 15701651) 1 Hasegawa M....Suda T. (2005) Helicobacter pylori binds to CD74 on gastric epithelial cells and stimulates interleukin-8 production. (PubMed id 15845476) 1 Beswick E.J....Reyes V.E. (2005) The mitogen-activated protein kinase dependent expression of prostaglandin H synthase-2 and interleukin-8 messenger ribonucleic acid by myometrial cells: the differential effect of stretch and interleukin-1{beta}. (PubMed id 15784717) 1 Sooranna S.R....Johnson M.R. (2005) Modulation of HIV-1 transcription by cytokines and chemokines. (PubMed id 16375755) 1 Copeland K.F. (2005) Helicobacter pylori-induced IL-8 production by gastric epithelial cells up-regulates CD74 expression. (PubMed id 15972644) 1 Beswick E.J....Reyes V.E. (2005) Inhibition by adiponectin of IL-8 production by human macrophages upon coculturing with late apoptotic cells. (PubMed id 16039610) 1 Saijo S....Kobayashi Y. (2005) Activation of the Nrf2/antioxidant response pathway increases IL-8 expression. (PubMed id 16220540) 1 Zhang X....Rovin B.H. (2005) Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations. (PubMed id 16125276) 1 Boldrini L....Fontanini G. (2005) CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway. (PubMed id 15579377) 1 Sturm A....Dignass A.U. (2005) Macrolide-affected Toll-like receptor 4 expression from Helicobacter pylori-infected monocytes does not modify interleukin-8 production. (PubMed id 15866212) 1 Park J.Y....Hahm J.S. (2005) Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. (PubMed id 15650394) 1 Biswas S.K....Rahman I. (2005) IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis. (PubMed id 15454487) 1 Emadi S....Le Bousse-Kerdiles M.C. (2005) Human immunodeficiency virus-1 Tat protein up-regulates interleukin-6 and interleukin-8 expression in human breast cancer cells. (PubMed id 16273337) 1 Lee Y.W....Toborek M. (2005) Collection and storage of human blood cells for mRNA expression profiling: a 15-month stability study. (PubMed id 15976103) 1 Marteau J.B....Visvikis-Siest S. (2005) Contribution of protein kinase A and protein kinase C pathways in ultraviolet B-induced IL-8 expression by human keratinocytes. (PubMed id 15760676) 1 Grandjean-Laquerriere A....Guenounou M. (2005) IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia. (PubMed id 15652404) 1 Franciosi S....McLarnon J.G. (2005) E1A expression dysregulates IL-8 production and suppresses IL-6 production by lung epithelial cells. (PubMed id 16185356) 1 van den Berg A....Lutter R. (2005) Outer membrane protein P6 of nontypeable Haemophilus influenzae is a potent and selective inducer of human macrophage proinflammatory cytokines. (PubMed id 15845475) 1 Berenson C.S....Sethi S. (2005) [The relationship between Helicobacter pylori infection and IL-8 expression in remnant stomach mucosa] (PubMed id 15989802) 1 Xing C.Z....Yuan Y. (2005) IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR. (PubMed id 15514971) 1 Suswam E.A....King P.H. (2005) Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis? (PubMed id 16195477) 1 Henrichot E....Meier C.A. (2005) TNF-alpha induces interleukin-8 and endothelin-1 expression in human endothelial cells with different redox pathways. (PubMed id 15652492) 1 Zhao R.Z....Chen C. (2005) In vitro crosstalk between fibroblasts and native human acute myelogenous leukemia (AML) blasts via local cytokine networks results in increased proliferation and decreased apoptosis of AML cells as well as increased levels of proangiogenic Interleukin 8. (PubMed id 15607368) 1 Ryningen A....Bruserud O. (2005) Hepatitis C virus core protein and hepatitis activity are associated through transactivation of interleukin-8. (PubMed id 15962221) 1 Hoshida Y....Omata M. (2005) Synergy between IL-8 and GM-CSF in reproductive tract epithelial cell secretions promotes enhanced neutrophil chemotaxis. (PubMed id 15541716) 1 Shen L....Fanger M.W. (2004) IL-8 responsiveness defines a subset of CD8 T cells poised to kill. (PubMed id 15292066) 1 Hess C....Luster A.D. (2004) Regulation of interleukin-8 secretion in human intestinal epithelial Caco-2 cells by alpha-humulene. (PubMed id 15630185) 1 Satsu H....Shimizu M. (2004) In situ analysis of interleukin-1-induced transcription of cox-2 and il-8 in cultured human myometrial cells. (PubMed id 14645117) 1 Soloff M.S....Anderson G.D. (2004) Interleukin-8/CXCL8 forms an autocrine loop in fetal intestinal mucosa. (PubMed id 15181190) 1 Maheshwari A....Calhoun D.A. (2004) Adherence to, invasion by, and cytokine production in response to serotype VIII group B Streptococci. (PubMed id 15271933) 1 Mikamo H....Onderdonk A.B. (2004) Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor-kappaB pathway. (PubMed id 15385484) 1 Wu S....Sears C.L. (2004) Increased CXCL8 (IL-8) expression in Multiple Sclerosis. (PubMed id 15342208) 1 Lund B.T....Weiner L.P. (2004) Extracellular catalase induces cyclooxygenase 2, interleukin 8, and stromelysin genes in primary human chondrocytes. (PubMed id 15667946) 1 Litvinov D. and Turpaev K. (2004) Group IB secretory phospholipase A2 stimulates CXC chemokine ligand 8 production via ERK and NF-kappa B in human neutrophils. (PubMed id 15528384) 1 Jo E.J....Bae Y.S. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 2 Ota T.... Sugano S. (2004) Modulation of PPARalpha expression and inflammatory interleukin-6 production by chronic glucose increases monocyte/endothelial adhesion. (PubMed id 15001458) 1 Srinivasan S....Hedrick C.C. (2004) CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters. (PubMed id 15079071) 1 Marinari B....Tuosto L. (2004) IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. (PubMed id 15178568) 1 Boekholdt S.M....Khaw K.T. (2004) Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection. (PubMed id 15057743) 1 Yamaoka Y....Graham D.Y. (2004) IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers. (PubMed id 15218164) 1 Talavera D....Meza I. (2004) Induction of interleukin-8 in T84 cells by Vibrio cholerae. (PubMed id 14688120) 1 Zhou X....Kaper J.B. (2004) Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. (PubMed id 15489227) 1 Buss H....Kracht M. (2004) Candida albicans and Saccharomyces cerevisiae induce interleukin-8 production from intestinal epithelial-like Caco-2 cells in the presence of butyric acid. (PubMed id 15196572) 1 Saegusa S....Hosoi T. (2004) Candida albicans and Streptococcus salivarius modulate IL-6, IL-8, and TNF-alpha expression and secretion by engineered human oral mucosa cells. (PubMed id 15469436) 1 Mostefaoui Y....Rouabhia M. (2004) Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells. (PubMed id 15331599) 1 Pawliczak R....Shelhamer J.H. (2004) Oxidant-injured airway epithelial cells upregulate thioredoxin but do not produce interleukin-8. (PubMed id 15096327) 1 Oslund K.L....Hyde D.M. (2004) Adenovirus type 7 induces interleukin-8 in a lung slice model and requires activation of Erk. (PubMed id 15047831) 1 Booth J.L....Metcalf J.P. (2004) Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells. (PubMed id 15169673) 1 Sparkman L. and Boggaram V. (2004) Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. (PubMed id 15542429) 1 Sparmann A. and Bar-Sagi D. (2004) Particle-epithelial interaction: effect of priming and bystander neutrophils on interleukin-8 release. (PubMed id 14630611) 1 Ning Y....Kobzik L. (2004) hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. (PubMed id 15521010) 1 Vavricka S.R....Chang E.B. (2004) Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis. (PubMed id 15481145) 1 Conti L....Gessani S. (2004) Reactive oxygen and nitrogen species differentially regulate Toll-like receptor 4-mediated activation of NF-kappa B and interleukin-8 expression. (PubMed id 15039334) 1 Ryan K.A....Ernst P.B. (2004) Mechanisms underlying differential expression of interleukin-8 in breast cancer cells. (PubMed id 15208657) 1 Freund A....Lazennec G. (2004) Modulation of cytokine-induced production of IL-8 in vitro by interferons and glucocorticosteroids. (PubMed id 15379213) 1 Nyhlen K....Srinivas U. (2004) Infection of primary human macrophages with hepatitis C virus in vitro: induction of tumour necrosis factor-alpha and interleukin 8. (PubMed id 14718619) 1 Radkowski M....Laskus T. (2004) Gliadin stimulates human monocytes to production of IL-8 and TNF-alpha through a mechanism involving NF-kappaB. (PubMed id 15280021) 1 Jelinkova L....Tlaskalova-Hogenova H. (2004) Human amniotic fluid cells are able to produce IL-6 and IL-8. (PubMed id 15209388) 1 Mazzucchelli I....Polatti F. (2004) Association of adherence and motility in interleukin 8 induction in human intestinal epithelial cells by Vibrio cholerae. (PubMed id 15158775) 1 Sarkar M. and Chaudhuri K. (2004) Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway. (PubMed id 15143062) 1 Yeh M....Berliner J.A. (2004) Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells. (PubMed id 14625302) 1 Hedvat C.V.... Nimer S.D. (2004) Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha. (PubMed id 15337758) 1 Imamura R....Suda T. (2004) SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival. (PubMed id 15494311) 1 Hoberg J.E....Mayo M.W. (2004) Plasminogen activator inhibitor-1 supports IL-8-mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial IL-8/heparan sulfate/syndecan-1 complexes. (PubMed id 12902511) 1 Marshall L.J....Shute J.K. (2003) Augmentation of Actinobacillus actinomycetemcomitans invasion of human oral epithelial cells and up-regulation of interleukin-8 production by saliva CD14. (PubMed id 14500479) 1 Takayama A....Sugawara S. (2003) Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells. (PubMed id 12654834) 1 Zhou X....Kaper J.B. (2003) Interleukin-8 is differentially expressed by human-derived monocytic cell line U937 infected with Mycobacterium tuberculosis H37Rv and Mycobacterium marinum. (PubMed id 14500465) 1 Song C.H....Jo E.K. (2003) CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch of human airway smooth muscle cells. (PubMed id 12637525) 1 Kumar A....Boriek A.M. (2003) The effect of oxidative stress on histone acetylation and IL-8 release. (PubMed id 12565901) 1 Tomita K....Adcock I.M. (2003) Differential interleukin-8 and nitric oxide production in epithelial cells induced by mucosally invasive and noninvasive Trypanosoma cruzi trypomastigotes. (PubMed id 12933891) 1 Eickhoff C.S....Hoft D.F. (2003) Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. (PubMed id 12573991) 1 Gilmour P.S....MacNee W. (2003) Myeloid related protein-8/14 stimulates interleukin-8 production in airway epithelial cells. (PubMed id 12748056) 1 Ahmad A....Stockley R.A. (2003) Location and intensity of IL-8 and TGF-beta2 mRNA production in the fimbrial compartment of fallopian tubes and IL-10 in the endometrium in patients with pyoinflammatory adnexal diseases. (PubMed id 12802400) 1 Zhdanov A.V....Sukhikh G.T. (2003) Atypical methylation of the interleukin-8 gene correlates strongly with the metastatic potential of breast carcinoma cells. (PubMed id 14623984) 1 De Larco J.E....Furcht L.T. (2003) Levels of interleukin-6 and interleukin-8 in seminal fluid of men attending an andrological clinic. (PubMed id 12653788) 1 Friebe K....Krause W. (2003) Selective effects of interleukin (IL)-15 on antifungal activity and IL-8 release by polymorphonuclear leukocytes in response to hyphae of Aspergillus species. (PubMed id 12898448) 1 Winn R.M....Walsh T.J. (2003) Expression and regulation of interleukin-8 in human fallopian tubal cells. (PubMed id 12634636) 1 Mulayim N....Arici A. (2003) Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma. (PubMed id 12594058) 1 Boulares A.H....Smulson M.E. (2003) A proinflammatory cytokine response is present in the fetal placental vasculature in placental insufficiency. (PubMed id 14634584) 1 Wang X....Trudinger B. (2003) Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-kappa B pathways. (PubMed id 12584113) 1 Zhao D....Pothoulakis C. (2003) Glutamine decreases lipopolysaccharide-induced IL-8 production in Caco-2 cells through a non-NF-kappaB p50 mechanism. (PubMed id 12849706) 1 Huang Y....Neu J. (2003) Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia. (PubMed id 12548717) 1 Xiong H....Gendelman H.E. (2003) Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. (PubMed id 12952969) 1 Rotter V....Smith U. (2003) Vaginal cytokines in normal pregnancy. (PubMed id 14634582) 1 Donders G.G....Spitz B. (2003) Gastric mucosal cytokine responses in Helicobacter pylori-infected patients with gastritis and peptic ulcers. Association with inflammatory parameters and bacteria load. (PubMed id 12738388) 1 Holck S....Andersen L.P. (2003) Candida albicans induced interleukin 8 production by human keratinocytes. (PubMed id 12727029) 1 Kano R....Nakamura Y. (2003) Impact of endoscopically minimal involvement on IL-8 mRNA expression in esophageal mucosa of patients with non-erosive reflux disease. (PubMed id 14669337) 1 Kanazawa Y....Kohno S. (2003) Identification of interleukin-8 converting enzyme as cathepsin L. (PubMed id 12818188) 1 Ohashi K....Sano E. (2003) Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes. (PubMed id 14578856) 1 Joshi-Barve S....McClain C.J. (2003) Increased expression of TNF-alpha, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels. (PubMed id 12876073) 1 Lihn A.S....Andersen O. (2003) Serum and cyst fluid levels of interleukin (IL) -6, IL-8 and tumour necrosis factor-alpha in women with endometriomas and benign and malignant cystic ovarian tumours. (PubMed id 12871882) 1 Darai E....Quang N.T. (2003) Activation of NF-kappaB and IL-8 by Yersinia enterocolitica invasin protein is conferred by engagement of Rac1 and MAP kinase cascades. (PubMed id 14641180) 1 Grassl G.A....Autenrieth I.B. (2003) Modulation of NF-kappaB activity by exchange of dimers. (PubMed id 12820969) 1 Saccani S....Natoli G. (2003) Enhanced cytokine synthesis of leukocytes by a beta-glucan preparation, SCG, extracted from a medicinal mushroom, Sparassis crispa. (PubMed id 19180796) 1 Nameda S....Ohno N. (2003) Transcriptional regulation of interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid-dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid-independent activation of NF-kappaB. (PubMed id 12748173) 1 Zhu Y.M....Knox A.J. (2003) TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. (PubMed id 12702497) 1 Yu Y....Gewirtz A.T. (2003) Stimulation of PAI-1 and adipokines by glucose in human adipose tissue in vitro. (PubMed id 14550286) 1 He G....Richelsen B. (2003) Von Willebrand factor targets IL-8 to Weibel-Palade bodies in an endothelial cell line. (PubMed id 12729795) 1 Romani de Wit T....van Mourik J.A. (2003) Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis. (PubMed id 12586630) 1 Dudek A.Z....Slungaard A. (2003) Red blood cells stimulate human lung fibroblasts to secrete interleukin-8. (PubMed id 12797546) 1 Fredriksson K....Skold C.M. (2003) Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. (PubMed id 12654635) 1 Frevert C.W....Martin T.R. (2003) Interleukin-8 gene and protein expression are up-regulated by interleukin-1beta in normal human ovarian cells and a granulosa tumor cell line. (PubMed id 12524080) 1 Fujii A....Terakawa N. (2003) Regulation of interleukin-8 by interleukin-10 and transforming growth factor beta in human monocytes infected with mycobacterium bovis. (PubMed id 12093676) 1 Mendez-Samperio P....Palma J. (2002) Endotoxin-stimulated production of IL-6 and IL-8 is increased in short-term cultures of whole blood from healthy term neonates. (PubMed id 12096927) 1 Dembinski J....Bartmann P. (2002) Effects of interleukin-8 on granulation tissue maturation. (PubMed id 12384994) 1 Moyer K.E....Ehrlich H.P. (2002) Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways. (PubMed id 12056817) 1 Iwahashi N....Takahashi M. (2002) HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. (PubMed id 12089333) 1 Cicala C....Fauci A.S. (2002) Inflammation in the wall of abdominal aortic aneurysm and its role in the symptomatology of aneurysm. (PubMed id 12850808) 1 Treska V....Tonar Z. (2002) Interleukin-8-induced proliferation, survival, and MMP production in CXCR1 and CXCR2 expressing human umbilical vein endothelial cells. (PubMed id 12453441) 1 Li A....Singh R.K. (2002) [The level of IL-8 in the serum of patients suffering from chronic hepatic diseases and primary hepatocellular carcinoma] (PubMed id 12502445) 1 Tong L....Lu B. (2002)