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IL7 Gene

protein-coding GIFtS: 65

GC08M079807

interleukin 7
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
IL-7 ^¹, ², ³

Descriptions
IL7 nirs variant 6 ^²
interleukin 7 ^²

External Ids
HGNC: 6023¹
Entrez Gene: 3574²
UniProtKB: P13232³
Ensembl: ENSG00000104432⁷

Search outside databases for aliases for IL7 gene

Previous GC identifers: GC08M078689 GC08M079682 GC08M079311 GC08M079694

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for IL7:

The protein encoded by this gene is a cytokine important for B and T cell development. This

cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B

cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of

the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced

locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor

for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an

essential role in lymphoid cell survival. [provided by RefSeq]

UniProtKB/Swiss-Prot: IL7_HUMAN, P13232

Function: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid

progenitors. It is important for proliferation during certain stages of B-cell maturation

Gene Wiki entry for IL7 (Interleukin_7)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the IL7 gene

Entrez Gene cytogenetic band: 8q12-q13 Ensembl cytogenetic band: 8q21.12 HGNC cytogenetic band: 8q12-q13

IL7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M079807: (about GC identifiers)

Start:	79,807,560 bp from pter
End:	79,880,313 bp from pter
Size:	72,754 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000008.9 NT_008183.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: IL7_HUMAN, P13232 (See protein sequence)

Recommended Name: Interleukin-7 precursor

Size: 177 amino acids; 20187 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1IL7 (3D)

3DI2 (3D)

3DI3 (3D)

REFSEQ proteins: NP_000871.1

ENSEMBL proteins:

ENSP00000368408 ENSP00000263851 ENSP00000368409

Human Recombinant Proteins

	Invitrogen human recombinant proteins for IL7
	Millipore Purified and/or Recombinant IL7 Protein
	Sigma-Aldrich Proteins for IL7
	R&D Systems Recombinant & Natural Proteins for IL7 (IL-7)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (IL7)
	Human Recombinant Proteins from Abnova (IL7)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	2643102
GO:0005615	extracellular space	IEA	--

About this table

Antibodies for IL7:

	Invitrogen Antibodies for IL7
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for IL7
	R&D Systems Antibodies for IL7 (IL-7)
	Antibodies from Abcam (IL7), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (IL7)
	Novus Biologicals Antibodies for IL7

Assays for IL7:

	Invitrogen Assays for IL7
	Millipore Kits and Assays for the Analysis of IL7
	R&D Systems Flow Cytometry Kits for IL7 (IL-7) (see all)
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P13232

ProtoNet protein and cluster: P13232

2 Blocks protein families:

IPB000226 Interleukin-7/interleukin-9

IPB001181 Interleukin-7

UniProtKB/Swiss-Prot: IL7_HUMAN, P13232

Similarity: Belongs to the IL-7/IL-9 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IL7)
		Millipore RNAi Products for the Analysis of IL7 Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000880

Applied Biosystems Silencer® siRNAs for IL7

Sigma-Aldrich siRNA and siRNA Panels for IL7

Sigma-Aldrich shRNA Panels and shRNA for IL7

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for IL7
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000880
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000880
untagged cDNA clone in CMV expression vector: NM_000880

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000880

UniProtKB/Swiss-Prot: IL7_HUMAN, P13232

Function: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid

progenitors. It is important for proliferation during certain stages of B-cell maturation

Genatlas biochemistry entry for IL7:

interleukin 7,20.2kDa,stimulating the proliferation of lymphoid progenitor cells

2 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Il7):

hematopoietic system

immune system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005125	cytokine activity	IEA	--
GO:0005139	interleukin-7 receptor binding	TAS	2643102
GO:0005515	protein binding	IPI	8266077

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for IL7

5/106 Interacting proteins for IL7 (ENSP00000263851³ P13232¹) via UniProtKB, MINT, and/or STRING (see all 106 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IL2RG	P31785¹	STRING (score=.999) EBI-80516, EBI-80475
IL7R	P16871¹	STRING (score=.999) EBI-80516, EBI-80490
IL4	ENSP00000231449³	STRING (score=.998)
IL2	ENSP00000226730³	STRING (score=.996)
IL15	ENSP00000296545³	STRING (score=.992)

About this table

5/8 Gene Ontology (GO) biological process terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006959	humoral immune response	TAS	2643102
GO:0007267	cell-cell signaling	TAS	2643102
GO:0008284	positive regulation of cell proliferation	TAS	2643102
GO:0009887	organ morphogenesis	TAS	2643102
GO:0030890	positive regulation of B cell proliferation	ISS	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for IL7
10/35 Novoseek chemical compound relationships for IL7 gene (see all 35 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
rantes	58.98	48	16011532 (11), 12634395 (6), 14516451 (3), 16044003 (2) (see all 22)
alpha-galactosylceramide	45.54	14	11150537 (3), 10715513 (3), 10594688 (3), 15368282 (1)
tyrosine	44.40	43	7694866 (3), 1708885 (2), 12750561 (2), 7957877 (2) (see all 30)
hemocyanin	37.35	7	9815643 (1), 9111580 (1), 7615008 (1), 9935194 (1) (see all 7)
ionomycin	36.25	3	16045733 (1), 1292630 (1)
thymidine	31.40	10	8397935 (2), 8152260 (1), 15921626 (1), 9024505 (1) (see all 8)
phosphatidylinositol	26.46	13	7522165 (2), 9614102 (1), 11739504 (1), 12354940 (1) (see all 7)
c-d4t	21.49	1	12470268 (1)
il-12	19.38	4	12525379 (2), 16943231 (1)
il 10	17.22	3	19064561 (1), 10995008 (1), 16943231 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IL7)
		Millipore RNAi Products for the Analysis of IL7 Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000880

Sigma-Aldrich siRNA and siRNA Panels for IL7

Sigma-Aldrich shRNA Panels and shRNA for IL7

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000880

REFSEQ mRNAs for IL7 gene:

NM_000880.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000880

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000880
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000880
                                 untagged cDNA clone in CMV expression vector: NM_000880

Additional cDNA sequence:

AB102879.1 AB102882.1 AB102883.1 AB102885.1 AB102893.1 AK226000.1 AK291538.1 BC032487.1

BC047698.1 J04156.1

7 DOTS entries:

DT.453043 DT.101982641 DT.120632347 DT.120632372 DT.120632362 DT.100745646 DT.305914

24/33 AceView cDNA sequences (see all 33 ):

CD013921 BM978895 BX107087 AI797222 J04156 CD013919 BC047698 CD013923

CD013922 BX105178 NM_000880 AA683422 CD013920 CB961906 BI869380 BM919542

BC032487 AI688740 BX508877 AA626244 BU632596 AI539460 BP367761 BI520517

highest scoring ESTs for IL7:

J04156 AU136355 AW383303 AW383313 BX508877 BC032487 BC047698 CB961906 AA287945 AA288010

Unigene Cluster for IL7:

Interleukin 7

Hs.591873 [show with all ESTs]

Unigene Representative Sequence: BC047698

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for IL7

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	^	5	^	6
SP1:													-
SP2:											-		-
SP3:													-				-		-
SP4:

About this scheme

ECgene alternative splicing isoforms for IL7

3 Ensembl transcripts including schematic representations:

ENST00000379113 ENST00000263851 ENST00000379114

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

IL7 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IL7

¹ / ² / ³

4 probe-sets matching IL7 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1159_at²^{, 3}	U95-A	1	1.00	1.00	0.92	0.89	J04156	1.00	0.90	0.95	1
33966_at²^{, 3}	U95-A	1	1.00	1.00	0.86	1.50	M29053	0.20	1.00	0.72	1
206693_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000880	0.60	1.00	0.82	1
206693_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AAAGAAATTG

SOURCE GeneReport for Unigene cluster: Hs.591873
Expression variation in blood from EXPOLDB for IL7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IL7 gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	IL7¹	--	interleukin 7	99.81(n) 100(a)	464245 XM_519820.2 XP_519820.2
cow (Bos taurus)	IL7¹	--	interleukin 7	84.85(n) 74.43(a)	280827 NM_173924.2 NP_776349.1
rat (Rattus norvegicus)	Il7¹	--	interleukin 7	79.78(n) 71.33(a)	25647 NM_013110.2 NP_037242.2
mouse (Mus musculus)	Il7^{1, 5}	3 (6.60 cM)⁵	interleukin 7^{1, 5}	80.61(n)¹ 69.93(a)¹	16196¹ NM_008371.3¹ NP_032397.1¹ AK040399⁵ AK041307⁵ (see all 18)

About this table Species with no ortholog for IL7

ENSEMBL Gene Tree for IL7

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/265 NCBI SNPs in IL7 are shown (see all 265 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 93)

AB	SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs11777564^1,2	A,C,F,H	79881589(+)	`GGTCTT/CTAGCC`	1	--	ng3¹ tfbs³		4	EU EA WA	420
	rs7007634^1,2	A,C,F,H	79882152(+)	`CAGGAA/GAGGCA`	1	--	ng3¹		7	EU EA WA NA	560
	rs2583759^1,2	A,C,F,H	79807519(+)	`TCTCAT/CCTTAA`	1	--	ng5¹		4	EU EA WA	408
	rs2887501^1,2	C,F,H,O	79881135(+)	`ctggtA/CaggAG`	1	--	ng3¹		7	EU EA WA NA	560
--	rs35852577^1,2	C,F	79807752(+)	`AGACAA/-GTTAT`	1	--	ut3¹		1	EU	270
	rs6997891^1,2	F,H	79880560(+)	`ACTATG/TACTTC`	1	--	ng3¹ tfbs³		4	EU EA WA	420
	rs11986057^1,2	H	79807235(+)	`CATCAG/TCACAT`	1	--	ng5¹		4	EU EA WA	420
	rs17506013^1,2	F	79881947(+)	`AGCAGC/TATTGA`	1	--	ng3¹		3	NA	140
	rs2717536^1,2	A,C,F,H,O	79864431(-)	`CCTGCC/TTCCCC`	1	--	int¹		7	EU EA WA NA	560
	rs1441850^1,2	A,C,F,H,O	79820221(+)	`ATTTCT/CCCAAA`	1	--	int¹		12	NA EA EU WA	842

About this table

HapMap Linkage Disequilibrium images for IL7 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 146660

10/96 Novoseek disease relationships for IL7 gene (see all 96 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
severe combined immunodeficiency, x-linked	87.49	36	8026467 (1), 8605322 (1), 14966353 (1), 7481768 (1) (see all 24)
lymphoblastic leukemia acute	62.50	34	7535143 (2), 2189505 (2), 7596167 (2), 2388482 (2) (see all 20)
lymphopenia	61.55	37	15642146 (3), 10837414 (1), 16313348 (1), 16461915 (1) (see all 23)
necrosis	58.19	133	8943702 (4), 10438843 (2), 17448250 (2), 17185327 (2) (see all 99)
severe combined immunodeficiency	58.17	6	15661025 (1), 7777571 (1), 12411295 (1), 8916956 (1) (see all 5)
t-all	55.81	41	14607751 (5), 16019476 (4), 10891465 (4), 17296584 (3) (see all 13)
leukemia	53.39	46	15949292 (3), 1996110 (2), 10210778 (2), 1921447 (2) (see all 31)
hiv infections	47.27	44	19372891 (3), 12847229 (3), 11590518 (3), 9562375 (2) (see all 24)
sezary syndrome	45.91	7	8113839 (2), 9548535 (1), 9639524 (1), 9129044 (1)
lymphoma t-cell cutaneous	45.64	11	11675351 (2), 9017129 (1), 16322477 (1), 8915148 (1) (see all 6)

About this table

Human Gene Mutation Database: IL7
Human Genome Epidemiology Navigator: IL7 (5 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

Antibody Therapy Promising for Pediatric Neuroblastoma

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/1146 PubMed articles for IL7 gene (see all 1146 ):

Comparative model building of interleukin-7 using interleukin-4 as a template: a structural hypothesis that displays atypical surface chemistry in helix D important for receptor activation. (PubMed id 10850801)^{1, 3, 4} Cosenza L.... Smith T.F. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Disulfide bond assignment in human interleukin-7 by matrix-assisted laser desorption/ionization mass spectroscopy and site-directed cysteine to serine mutational analysis. (PubMed id 9407080)^{3, 4} Cosenza L.... Murphy J.R. (1997)
Prediction of the three-dimensional structure of human interleukin-7 by homology modeling. (PubMed id 8862549)^{3, 4} Kroemer R.T.... Richards W.G. (1996)
Characterization of the human and murine IL-7 genes. (PubMed id 2329282)^{3, 4} Lupton S.D.... Goodwin R.G. (1990)
Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. (PubMed id 2643102)^{3, 4} Goodwin R.G.... Namen A.E. (1989)
A three-base-deletion polymorphism in the upstream non-coding region of human interleukin 7 (IL-7) gene could enhance levels of IL-7 expression. (PubMed id 17373935)^{1, 3} Song H....Shioda T. (2007)
Biological and clinical implications of interleukin-7 and lymphopoiesis. (PubMed id 10390077)^{1, 3} Appasamy P.M. (1999)
Interleukin-7 (IL-7) in patients receiving intensive chemotherapy for acute myelogenous leukemia: studies of systemic IL-7 Levels and IL-7 responsiveness of circulating T lymphocytes. (PubMed id 12433286)^{1, 3} Wendelbo O....Bruserud O. (2002)
Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice. (PubMed id 12847229)^{1, 3} Napolitano L.A....McCune J.M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3574	HGNC: 6023	AceView: IL7	Ensembl:ENSG00000104432	euGenes: HUgn3574
ECgene: IL7	H-InvDB: IL7

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Interleukin_7

Licensable Technologies for IL7
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for IL7:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for IL7-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IL7		Antibodies for IL7
	Explore super-pooled esiRNAs		Proteins for IL7
	Lentivirus-delivered shRNAs for IL7		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (IL7)
	Antibodies (IL7)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for IL7

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for IL7

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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IL7 Gene at Home site.
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IL7 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for IL7

Summaries
for IL7

Genomic Location
for IL7

Proteins
for IL7

Protein Domains/
Families
for IL7

Gene Function
for IL7

Pathways & Interactions
for IL7

Drugs & Compounds
for IL7

Transcripts
for IL7

Expression
for IL7

Orthologs
for IL7

Paralogs
for IL7

SNPs/Variants
for IL7

Disorders & Mutations
for IL7

Medical News
for IL7

Publications
for IL7

Search for IL7

Genome Databases showing IL7

Other Databases showing IL7

Specialized Databases showing IL7

Licensable Technologies
for IL7

Services
for IL7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IL7 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor IL7

Summariesfor IL7

Genomic Locationfor IL7

Proteinsfor IL7

Protein Domains/Familiesfor IL7

Gene Functionfor IL7

Pathways & Interactionsfor IL7

Drugs & Compoundsfor IL7

Transcriptsfor IL7

Expression for IL7

Orthologsfor IL7

Paralogsfor IL7

SNPs/Variantsfor IL7

Disorders & Mutationsfor IL7

Medical Newsfor IL7

Publicationsfor IL7

Search for IL7

Genome Databases showing IL7

Other Databases showing IL7

Specialized Databases showing IL7

Licensable Technologiesfor IL7

Servicesfor IL7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for IL7

Summaries
for IL7

Genomic Location
for IL7

Proteins
for IL7

Protein Domains/
Families
for IL7

Gene Function
for IL7

Pathways & Interactions
for IL7

Drugs & Compounds
for IL7

Transcripts
for IL7

Expression
for IL7

Orthologs
for IL7

Paralogs
for IL7

SNPs/Variants
for IL7

Disorders & Mutations
for IL7

Medical News
for IL7

Publications
for IL7

Licensable Technologies
for IL7

Services
for IL7