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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IL3RA Gene

protein-coding   GIFtS: 62
GCID: GC0XP001415

interleukin 3 receptor, alpha (low affinity)

 Explore 33 diseases affiliated with
IL3RA via our new
 Human Malady Compendium 
Biological research products
for IL3RA
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Interleukin 3 Receptor, Alpha (Low Affinity)1 2     IL-3R Subunit Alpha2 3
CD1231 2     IL3RAY2
IL-3R-Alpha1     IL3RX2
IL-3RA2 3     IL3RY2
IL3R2 3     HIL-3Ra1
CD123 Antigen2 3     IL-3 Receptor Alpha SP2 Isoform2
IL-3 Receptor Subunit Alpha2 3     Interleukin-3 Receptor Subunit Alpha2

External Ids:    HGNC: 60121   Entrez Gene: 35632   Ensembl: ENSG000001852917   OMIM: 3083855   UniProtKB: P269513   

Export aliases for IL3RA gene to outside databases

Previous GC identifers: GC00U990171 GC0YU900011 GC0XP9H0000 GC0YP001499 GC0XP001499


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL3RA:
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The
receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors
for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this
protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for
the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain
(CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively
spliced transcript variants encoding distinct isoforms have been found. (provided by RefSeq, Jun 2012)

UniProtKB/Swiss-Prot: IL3RA_HUMAN, P26951
Function: This is a receptor for interleukin-3

Gene Wiki entry for IL3RA


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_000024.9  NC_018934.1  NT_167196.1  NT_167204.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IL3RA gene promoter:
         STAT5A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL3RA promoter sequence
   Search SABiosciences Chromatin IP Primers for IL3RA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL3RA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.3 or Yp11.3   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.3 and Yp13.3

IL3RA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL3RA gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP001415:  view genomic region     (about GC identifiers)

Start:
1,455,509 bp from pter      End:
1,501,582 bp from pter
Size:
46,074 bases      Orientation:
plus strand

1 alternative location:
ChrY+ 1,405,509-1,451,582     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IL3RA_HUMAN, P26951 (See protein sequence)
Recommended Name: Interleukin-3 receptor subunit alpha precursor  
Size: 378 amino acids; 43330 Da
Subunit: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors
Subcellular location: Membrane; Single-pass type I membrane protein
Miscellaneous: The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y
chromosomes
Secondary accessions: A8K3F3 B9VI81 Q5HYQ7
Alternative splicing: 2 isoforms:  P26951-1   P26951-2   

Explore the universe of human proteins at neXtProt for IL3RA: NX_P26951

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P26951

  • IL3RA Protein expression data from MOPED and PaxDb:    About this image 
    IL3RA Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001254642.1  NP_002174.1  

    ENSEMBL proteins: 
     ENSP00000327890   ENSP00000414867   ENSP00000370878  
    Reactome Protein details: P26951
    Human Recombinant Protein Products for IL3RA: 
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    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    IL3RA for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IL3RA for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015321 IL6_recept-bd
     IPR003961 Fibronectin_type3
     IPR013783 Ig-like_fold
     IPR003532 Short_hematopoietin_rcpt_2_CS

    Graphical View of Domain Structure for InterPro Entry P26951

    ProtoNet protein and cluster: P26951

    1 Blocks protein family: IPB003532 Short hematopoietin receptor

    UniProtKB/Swiss-Prot: IL3RA_HUMAN, P26951
    Domain: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular
    transport and cell-surface receptor binding
    Domain: The box 1 motif is required for JAK interaction and/or activation
    Similarity: Belongs to the type I cytokine receptor family. Type 5 subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IL3RA_HUMAN, P26951
    Function: This is a receptor for interleukin-3

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004912interleukin-3 receptor activity TAS1833064
         
    IL3RA for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IL3RA:
     Wnt reporter downregulated 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/16 super-pathways (see all 16About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Interleukin receptor SHC signaling
    Interleukin receptor SHC signaling1.00
    Interleukin-3, 5 and GM-CSF signaling0.57
    Interleukin-2 signaling0.67
    The receptor is activated0.29
    Phosphorylated SHC1 recruits GRB2:GAB20.61
    Signaling by Interleukins0.25
    SHC1 mediates cytokine-induced phosphorylation of GAB20.61
    2TGF-Beta Pathway
    TGF-Beta Pathway1.00
    JAK-STAT Pathway0.57
    MAPK Family Pathway0.60
    JNK Pathway0.50
    3PEDF Induced Signaling
    STAT3 Pathway0.47
    Glucocorticoid Receptor Signaling0.27
    PGC1Alpha Pathway0.33
    Cytokine-cytokine receptor interaction0.26
    4Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    5Immune response_IL-2 activation and signaling pathway
    Immune response IL-3 activation and signaling pathway0.41
    Immune response_IL-3 activation and signaling pathway0.41

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for IL3RA
        Immune response IL-3 activation and signaling pathway

    5/15 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IL3RA (see all 15)
        MSP-RON Signaling
    STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    Glucocorticoid Receptor Signaling

    1 GeneGo (Thomson Reuters) Pathway for IL3RA
        Immune response IL-3 activation and signaling pathway

    1 BioSystems Pathway for IL3RA 
        IL-3 Signaling Pathway

    5/9        Reactome Pathways for IL3RA (see all 9)
        SHC1 mediates cytokine-induced phosphorylation of GAB2
    Interleukin receptor SHC signaling
    Interleukin-2 signaling
    Phosphorylated SHC1 recruits GRB2:GAB2
    Cytokine Signaling in Immune system


    4         Kegg Pathways  (Kegg details for IL3RA):
        Cytokine-cytokine receptor interaction
    Apoptosis
    Jak-STAT signaling pathway
    Hematopoietic cell lineage


    IL3RA for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL3RA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/45 Interacting proteins for IL3RA (P269512, 3 ENSP000003278904) via UniProtKB, MINT, STRING, and/or I2D (see all 45)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FYNP062412, 3, ENSP000003576564MINT-8111307 I2D: score=3 STRING: ENSP00000357656
    PLCG1P191742, 3, ENSP000002440074MINT-8112603 I2D: score=3 STRING: ENSP00000244007
    IL3P087003, ENSP000002968704I2D: score=4 STRING: ENSP00000296870
    CSF2RBP329273, ENSP000003840534I2D: score=3 STRING: ENSP00000384053
    CISHQ9NSE23, ENSP000004093464I2D: score=2 STRING: ENSP00000409346
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0036016cellular response to interleukin-3 TAS1833064
    GO:0038156interleukin-3-mediated signaling pathway TAS1833064

    IL3RA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    IL3RA for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for IL3RA

    1 DrugBank Compound for IL3RA    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    SargramostimColony-stimulating factor (see all 5)83869-56-1targetagonist17562355 17500228 16698686 17522711

    9 Novoseek chemical compound relationships for IL3RA gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gp 130 60.2 10 10068651 (3), 9389693 (3), 9890661 (1), 10414448 (1)
    tyrosine 43.5 16 10068651 (3), 7836750 (2), 2166606 (1), 15370201 (1) (see all 9)
    12-o-tetradecanoylphorbol 13-acetate 10.2 2 1290964 (1)
    glyceraldehyde 3-phosphate 10.1 1 7521187 (1)
    phosphatidylinositol 3.42 1 8939907 (1)
    thymidine 0 2 10764142 (1)
    threonine 0 1 8939907 (1)
    zinc 0 1 14527952 (1)
    phosphatidylcholine 0 2 7836750 (2)

    Search CenterWatch for drugs/clinical trials and news about IL3RA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IL3RA gene (2 alternative transcripts): 
    NM_001267713.1  NM_002183.3  

    Unigene Cluster for IL3RA:

    Interleukin 3 receptor, alpha (low affinity)
    Hs.632790  [show with all ESTs]
    Unigene Representative Sequence: BC035407
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000331035(uc004cps.3 uc011mhd.2) ENST00000432757 ENST00000381469


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    Additional cDNA sequence: 

    AK290568.1 BC035407.1 FJ550347.1 M74782.1 

    16 DOTS entries:

    DT.106458  DT.92423313  DT.92423314  DT.75184774  DT.100714210  DT.120652906  DT.120652854  DT.121315092 
    DT.121315254  DT.91696537  DT.97773494  DT.97817809  DT.102822929  DT.121315257  DT.91753594  DT.95247724 

    24/50 AceView cDNA sequences (see all 50):

    AW452270 AI379730 AI379750 BQ711484 BI772564 BU739504 CD368847 CD364754 
    BC035407 NM_002183 BF856898 CB528608 BM704769 BM693915 M74782 BM921786 
    BX507032 BI910175 BQ005358 AA722359 AI765858 CB266776 AI806887 BM906431 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for IL3RA    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                    -     -                                                         


    ECgene alternative splicing isoforms for IL3RA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IL3RA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATAAAGTGAT
    IL3RA Expression
    About this image
    See IL3RA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IL3RA

    SOURCE GeneReport for Unigene cluster: Hs.632790
        SABiosciences Expression via Pathway-Focused PCR Arrays including IL3RA: 

              Interferons & Receptors in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat
              Allergy & Asthma in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL3RA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IL3RA gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Il3ra1 interleukin 3 receptor, alpha chain 48.5(n)
    34.55(a)
      16188  NM_008369.1  NP_032395.1 
    chicken
    (Gallus gallus)
    Aves --
    CSF2RA6
    (see all 3)
    Uncharacterized protein
    (see all 3)
    26(a)
    24(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    1(133261693-133269306)
    1(133309331-133317524)


    ENSEMBL Gene Tree for IL3RA (if available)
    TreeFam Gene Tree for IL3RA (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IL3RA gene
    CSF2RA2  
    1 SIMAP similar gene for IL3RA using alignment to 3 protein entries:     IL3RA_HUMAN (see all proteins):
    CSF2RA

    IL3RA for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for IL3RA
         3 CNVs: 73900 73906 73901
    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for IL3RA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IL3RA for disorders           About GeneDecksing

    OMIM gene information: 308385    OMIM disorders: --

    20/33 diseases for IL3RA (see all 33):    About MalaCards
    hairy cell leukemia    lymphoblastic leukemia    systemic lupus erythematosus    myeloid leukemia
    diphtheria    lupus erythematosus    megakaryocytic leukemia    acute lymphoblastic leukemia
    leukemia    acute myeloid leukemia    herpes simplex    fanconi's anemia
    follicular lymphoma    acute leukemia    cblc    squamous cell carcinoma
    rubella    hodgkin's lymphoma    t-cell leukemia    myelodysplastic syndrome

    10/14 Novoseek disease relationships for IL3RA gene (see all 14)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    diphtheria 49.3 5 11368443 (1), 15003313 (1), 15928038 (1), 16882709 (1) (see all 5)
    acute leukemia 49 6 11726317 (2), 12950240 (1), 11021753 (1), 14671644 (1) (see all 5)
    myeloid leukemia 44 2 10764142 (1)
    leukemia 39.4 12 15003313 (2), 17667524 (2), 8547680 (1), 20064159 (1) (see all 5)
    leukemia hairy cell 31.3 7 11726317 (2), 15020268 (1)
    hematologic malignancies 24.7 3 11726317 (2)
    lymphoblastic leukemia acute 10.4 3 17205058 (1), 11726317 (1), 10720134 (1)
    necrosis 9.03 5 7687890 (1), 7545455 (1), 18552348 (1), 1825289 (1) (see all 5)
    hodgkin disease 8.87 1 12507919 (1)
    leukemia lymphocytic chronic 7.95 5 11726317 (1)

    Human Genome Epidemiology (HuGE) Navigator: IL3RA (6 documents)

    Export disorders for IL3RA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IL3RA gene, integrated from 9 sources (see all 186):
    (articles sorted by number of sources associating them with IL3RA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. (PubMed id 1833064)1, 2, 3 Kitamura T.... Miyajima A. (1991)
    2. A new isoform of IL-3 receptor alpha with novel differentiation activity and high affinity binding mode. (PubMed id 19109256)1, 2, 9 Chen J....Young I.G. (2008)
    3. Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. (PubMed id 17522711)1, 7, 9 Lencz T....Malhotra A.K. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis. (PubMed id 12351411)1, 9 Testa U....Peschle C. (2002)
    6. Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA) localized to the X-Y pseudoautosomal region. (PubMed id 8213838)1, 9 Milatovich A....Francke U. (1993)
    7. Interleukin-3 receptor in acute leukemia. (PubMed id 14671644)1, 9 Testa U....Peschle C. (2004)
    8. Changing expression of IL-3 and IL-5 receptors in cultured human eosinophils. (PubMed id 12943658)1, 9 Yoshimura-Uchiyama C....Hirai K. (2003)
    9. A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han population. (PubMed id 19281803)1, 9 Sun S....Zhang X.Y. (2009)
    10. Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population. (PubMed id 18547720)1, 9 Sun S....Zhang X.Y. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3563 HGNC: 6012 AceView: IL3RA Ensembl:ENSG00000185291 euGenes: HUgn3563
    ECgene: IL3RA Kegg: 3563 H-InvDB: IL3RA

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IL3RA Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for IL3RA Genetics and Cytogenetics in Oncology and Haematology
    SeattleSNPshttp://pga.gs.washington.edu/data/il3ra/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IL3RA gene:
    Search GeneIP for patents involving IL3RA

    GeneCards and IP:
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