IL36RN Gene
protein-coding GIFtS: 47
GCID: GC02P113817
|
|
interleukin 36 receptor antagonist(Previous names: interleukin 1 family, member 5 (delta) )
(Previous symbol: IL1F5)
| |
Aliases
for IL36RN gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Interleukin 36 Receptor Antagonist1 2 | | MGC298401 | | FIL1D1 2 3 5 | | PSORP2 | | IL1F51 2 3 5 | | Family Of Interleukin 1-Delta2 | | IL1HY11 2 3 5 | | IL-1 Related Protein 32 | | IL1RP31 2 3 5 | | IL-1F5 (IL-1HY1, FIL1-Delta, IL-1RP3, IL-1L1, IL-1-Delta)2 | | IL1L11 2 3 | | IL1F5 (Canonical Product IL-1F5a)2 | | FIL11 2 | | Interleukin-36 Receptor Antagonist Protein2 | | FIL1(DELTA)1 2 | | IL-1HY13 | | IL36RA1 2 | | IL-1L13 | | Interleukin 1 Family, Member 5 (Delta)1 2 | | IL-1RP33 | | IL-1F51 3 | | FIL1 Delta3 | | Interleukin-1 HY12 3 | | IL-1 Delta3 | | Interleukin-1 Receptor Antagonist Homolog 12 3 | | IL-1-Related Protein 33 | | Interleukin-1-Like Protein 12 3 | | Interleukin-1 Delta3 | | IL-1ra Homolog 12 3 | | Interleukin-1 Family Member 53 |
Export aliases for IL36RN gene to outside databases |
Summaries
for IL36RN gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IL36RN:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown tospecifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene andeight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively splicedtranscript variants encoding the same protein have been reported. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0Function: Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha(IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelialbarriers and takes part in local inflammatory response
Gene Wiki entry for IL36RN (IL1F5)
|
Genomic Views
for IL36RN gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for IL36RN
Other transcription factors
Search SABiosciences Chromatin IP Primers for IL36RN
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL36RN |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q14 Ensembl cytogenetic band: 2q13 HGNC cytogenetic band: 2q14IL36RN Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P113817: view genomic region
(about GC identifiers)
Start:
|
113,816,215 bp from pter |
End:
|
113,822,325 bp from pter |
Size:
|
6,111 bases |
Orientation:
|
plus strand |
|
Proteins
for IL36RN gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0 (See
protein sequence)Recommended Name: Interleukin-36 receptor antagonist protein Size: 155 amino acids; 16962 Da
Subcellular location: Secreted
Secondary accessions: A8K2I4 Q56AT9 Q7RTZ6Explore the universe of human proteins at neXtProt for IL36RN: NX_Q9UBH0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UBH0
IL36RN Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_036407.1 NP_775262.1
ENSEMBL proteins: ENSP00000259212 ENSP00000376896 ENSP00000409262
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005615 | extracellular space |
IEA | -- |
IL36RN for ontologies About GeneDecksing
IL36RN Antibody Products:
Assay Products for IL36RN: |
Protein
Domains /
Families
for IL36RN gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IL36RN for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UBH0ProtoNet protein and cluster: Q9UBH0 2 Blocks protein families: IPB000975 Interleukin-1 precursor family signature IPB003297 Interleukin-1 receptor antagonist precursor IL-1RA signature
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0Similarity: Belongs to the IL-1 family |
Function
for IL36RN gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0Function: Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha(IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelialbarriers and takes part in local inflammatory responseInduction: By phorbol ester (PMA) and bacterial lipopolysaccharides (LPS) treatment in macrophage cell line
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for IL36RN | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL36RN | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL36RN |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL36RN |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005125 | cytokine activity |
IEA | -- | | GO:0005152 | interleukin-1 receptor antagonist activity |
IEA | -- |
IL36RN for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Il1f5tm1Lex for IL36RN
7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Il1f5):
IL36RN for phenotypes About GeneDecksing
|
Pathways & Interactions
for IL36RN gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IL36RN
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/8 Interacting proteins for IL36RN (Q9UBH02, 3 ENSP000002592124) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001960 | negative regulation of cytokine-mediated signaling pathway |
TAS | 10512743 |
IL36RN for ontologies About GeneDecksing
|
Drugs & Compounds
for IL36RN gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IL36RN
Search CenterWatch for drugs/clinical trials and news about IL36RN / I36RA
|
Transcripts
for IL36RN gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IL36RN gene (2 alternative transcripts): NM_012275.2 NM_173170.1 Unigene Cluster for IL36RN: Interleukin 36 receptor antagonist Hs.516301 [show with all ESTs]Unigene Representative Sequence: AF1860943 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000346807(uc002tis.3) ENST00000393200(uc002tit.3) ENST00000437409
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for IL36RN | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL36RN | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL36RN |
Additional cDNA sequence: AF186094.1 AF201830.1 AF230377.1 AJ242737.1 AJ242738.1 AK002125.1 AK290249.1 AY359117.1 BC000945.2 BC024747.1 3 DOTS entries: DT.40316781 DT.97775169 DT.100709380 24/39 AceView cDNA sequences (see all 39): BX477358 BI089828 NM_012275 NM_173170 CA310393 BF509095 AF230377 AI469873 CR613851 BC024747 BF435174 AJ242737 AL545100 CD368042 AF201830 AW014217 AA722902 BX091500 BC000945 AI167887 AL570964 BI090567 R70041 AK002125
GeneLoc Exon Structure
|
Expression
for IL36RN gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IL36RN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See IL36RN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IL36RN
SOURCE GeneReport for Unigene cluster: Hs.516301
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0Tissue specificity: Predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes.Detected also in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin
SABiosciences Expression via Pathway-Focused PCR Array including IL36RN:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL36RN
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IL36RN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL36RN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL36RN | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL36RN |
Orthologs
for IL36RN gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IL36RN gene from 1/8 species (see all 8) About this table
ENSEMBL Gene Tree for IL36RN (if available)
TreeFam Gene Tree for IL36RN (if available) |
Paralogs
for IL36RN gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IL36RN gene
- IL36A2 IL1RN2 IL372 IL36G2 IL1F102
4 SIMAP similar genes for IL36RN using alignment to 2 protein entries: I36RA_HUMAN (see all proteins):IL1F10 IL1RN IL36A IL36G
IL36RN for paralogs About GeneDecksing
|
Genomic Variants
for IL36RN gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IL36RN (113816215 - 113822325 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IL36RN: --
Human Gene Mutation Database (HGMD): IL36RN
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL36RN |
|
Disorders
/ Diseases
for IL36RN gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IL36RN for disorders About GeneDecksing
OMIM gene information: 605507
OMIM disorders: --
UniProtKB/Swiss-Prot: I36RA_HUMAN, Q9UBH0
Defects in IL36RN are the cause of psoriasis generalized pustular (PSORP) [MIM:614204]. PSORP is alife-threatening disease defined by repeated flares of sudden onset consisting of diffuse erythematous skin eruptioncharacterized by rapid coverage with pustules, high-grade fever, asthenia, marked leukocytosis, and elevated serumlevels of C-reactive protein
13  diseases for IL36RN: About MalaCardsalopecia areata ankylosing spondylitis psoriatic arthritis alopecia
spondylitis rheumatoid arthritis skin disease hepatitis b
arthritis psoriasis hepatitis esophagitis
generalized pustular psoriasis
Export disorders for IL36RN gene to outside databases
|
Publications
for IL36RN gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IL36RN gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with IL36RN) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- IL1HY1: A novel interleukin-1 receptor antagonist gene. (PubMed id 10512743)1, 2, 3, 9 Mulero J.J....Ford J.E. (1999)
- Four new members expand the IL-1 superfamily. (PubMed id 10625660)1, 2, 3, 9 Smith D.E....Sims J.E. (2000)
- A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities. (PubMed id 11093146)1, 2, 9 Barton J.L.... Nicklin M.J.H. (2000)
- Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. (PubMed id 11466363)1, 2, 9 Debets R....Kastelein R.A. (2001)
- Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis. (PubMed id 21839423)1, 2 Onoufriadis A.... Barker J.N. (2011)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- A sequence-based map of the nine genes of the human interleukin-1 cluster. (PubMed id 11991722)1, 2 Nicklin M.J.H....Kornman K. (2002)
|
External Searches for IL36RN gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IL36RN gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IL36RN gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IL36RN gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IL36RN | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Interleukin_1 | | SeattleSNPs | http://pga.gs.washington.edu/data/il1f5/ |
|
| | |
About This Section
| Patent Information for IL36RN gene:
Search GeneIP for patents involving IL36RN
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IL36RN gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IL36RN | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IL36RN | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL36RN | | | OriGene Protein Over-expression Lysate for IL36RN | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IL36RN | | OriGene 3'-UTR Clone for IL36RN | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL36RN | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for IL36RN | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IL36RN | | OriGene Custom Protein Services for IL36RN | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IL36RN | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL36RN | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL36RN | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL36RN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL36RN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL36RN |
| |
 |  |  |  | |
| | | | Search Tocris compounds for IL36RN |
| |  |  |  |  | | | | | | Recombinant Protein for IL36RN |
|
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL36RN |
|  |  |  | | | | Search ThermoFisher Antibodies for IL36RN |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL36RN |
|
|
|
|
