Aliases for IL32 Gene
External Ids for IL32 Gene
Previous GeneCards Identifiers for IL32 Gene
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL32 Gene
IL32 (Interleukin 32) is a Protein Coding gene. Diseases associated with IL32 include venezuelan equine encephalitis and pancreatic cancer. Among its related pathways are Immune System and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include cytokine activity.
UniProtKB/Swiss-Prot for IL32 Gene
Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.