IL31RA Gene
protein-coding GIFtS: 52
GCID: GC05P055185
|
|
interleukin 31 receptor A
| |
Aliases for IL31RA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Interleukin 31 Receptor A1 2 | | GLMR2 5 | | CRL31 2 3 | | Glmr1 | | GLM-R1 2 3 | | PLCA22 | | IL-31RA1 2 3 | | PRO213842 | | GPL2 3 5 | | Class I Cytokine Receptor2 | | CRL1 2 | | Interleukin-31 Receptor Subunit Alpha2 | | Cytokine Receptor-Like 32 3 | | Soluble Type I Cytokine Receptor CRL32 | | Gp130-Like Monocyte Receptor2 3 | | ZcytoR173 | | HGLM-R1 | | IL-31R-Alpha1 | | IL-31 Receptor Subunit Alpha2 3 | | ZcytoR173 | | IL-31R Subunit Alpha2 3 | | Gp130-Like Receptor3 |
Export aliases for IL31RA gene to outside databasesPrevious GC identifers: GC00U913999 GC05P055165 GC05P052122 |
Summaries for IL31RA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for IL31RA: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130,is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions eitheras a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively splicedtranscript variants encoding different isoforms have been noted for this gene.(provided by RefSeq, Jun 2011) UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17Function: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1and STAT5. May function in skin immunity Gene Wiki entry for IL31RA
|
Genomic Views for IL31RA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the IL31RA gene promoter: AP-1 ATF-2 NRSF form 1 Pax-2 STAT5A NRSF form 2 STAT3 c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for IL31RA
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL31RA |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q11.2 Ensembl cytogenetic band: 5q11.2 HGNC cytogenetic band: 5q11.2IL31RA Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P055185: view genomic region
(about GC identifiers)
Start:
|
55,147,207 bp from pter |
End:
|
55,218,678 bp from pter |
Size:
|
71,472 bases |
Orientation:
|
plus strand |
|
Proteins for IL31RA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17 (See
protein sequence)Recommended Name: Interleukin-31 receptor subunit alpha precursor Size: 732 amino acids; 82954 Da
Subunit: Heterodimer with OSMR. Interacts with JAK1 and STAT3
Subcellular location: Cell membrane; Single-pass type I membrane protein (Probable)
Sequence caution: Sequence=AAS86444.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAS86445.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NIF8 Q2TBA1 Q6EBC3 Q6EBC4 Q6EBC5 Q6EBC6 Q6UWL8 Q8WYJ0Alternative splicing: 12 isoforms: Q8NI17-1 Q8NI17-2 Q8NI17-3 Q8NI17-4 Q8NI17-5 Q8NI17-6 Q8NI17-7 Q8NI17-8 Q8NI17-9 Q8NI17-10 Q8NI17-11 Q8NI17-12 (Major isoform. Functional IL31 receptor)Explore the universe of human proteins at neXtProt for IL31RA: NX_Q8NI17
Post-translational modifications:
N-glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NI17 IL31RA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001229565.1 NP_001229566.1 NP_001229567.1 NP_001229568.1 NP_620586.3 ENSEMBL proteins: ENSP00000380048 ENSP00000380046 ENSP00000415900 ENSP00000351935 ENSP00000427533 ENSP00000347047 ENSP00000297015 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
IL31RA for ontologies About GeneDecksing
IL31RA Antibody Products: Assay Products for IL31RA: |
Protein
Domains / Families for IL31RA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IL31RA for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NI17ProtoNet protein and cluster: Q8NI17 UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17Similarity: Belongs to the type I cytokine receptor family. Type 2 subfamilySimilarity: Contains 5 fibronectin type-III domains |
Function for IL31RA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17Function: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1and STAT5. May function in skin immunityInduction: Up-regulated in lesional keratinocytes of patients with atopic dermatitis. Up-regulated by IFNG/IFN-gammaand bacterial lipopolysaccharides (LPS)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IL31RA (NM_139017) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL31RA | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL31RA  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL31RA |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
IL31RA for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for IL31RA: Animal Models: Mouse knock-outs for IL31RA: Il31ratm1Lex Il31ratm1Ngh Il31ratm1Jagr 4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Il31ra):
IL31RA for phenotypes About GeneDecksing
|
Pathways & Interactions for IL31RA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IL31RA
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
 3 Interacting proteins for IL31RA (Q8NI173 ENSP000004159004) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
IL31RA for ontologies About GeneDecksing
|
Drugs & Compounds for IL31RA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
IL31RA for compounds About GeneDecksing
Browse Tocris compounds for IL31RA 1 Novoseek chemical compound relationship for IL31RA gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gp 130 |
64.5 |
7 |
15194700 (2), 11877449 (1) |
Search CenterWatch for drugs/clinical trials and news about IL31RA / IL31R 
|
Transcripts for IL31RA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for IL31RA gene (5 alternative transcripts): NM_001242636.1 NM_001242637.1 NM_001242638.1 NM_001242639.1 NM_139017.5 Unigene Cluster for IL31RA: Interleukin 31 receptor A Hs.55378 [show with all ESTs]Unigene Representative Sequence: NM_0012426387 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396836(uc003jqk.3 uc011cqj.2) ENST00000396834(uc003jqm.3 uc003jqn.3 uc010iwa.1) ENST00000447346(uc003jql.3 uc021xyq.1 uc003jqo.3) ENST00000359040 ENST00000490985 ENST00000354961 ENST00000297015
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IL31RA (NM_139017) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL31RA | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL31RA  |
Additional cDNA sequence: AF106913.1 AF486620.1 AK297938.1 AY358117.1 AY358740.1 AY499339.1 AY499340.1 AY499341.1 AY499342.1 BC110490.2 4 DOTS entries: DT.95351126 DT.40113745 DT.120874735 DT.120874749 17 AceView cDNA sequences: BX102881 AY499342 NM_139017 AY358740 AF486620 AY499339 AY499341 AY499340 AI123586 BU624025 AY358117 BG680553 AF106913 W16834 AI799583 BG191812 BG194774 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for IL31RA (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for IL31RA
|
Expression for IL31RA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IL31RA expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CTTTTGTTTT
About this image See IL31RA Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IL31RA
SOURCE GeneReport for Unigene cluster: Hs.55378 UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17Tissue specificity: Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, tracheaand skin. Detected in all of the myelomonocytic lineage. Expressed in CD14- and CD56-positive blood cells and bymacrophages (at protein level) SABiosciences Expression via Pathway-Focused PCR Arrays including IL31RA:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL31RA Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IL31RA | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL31RA | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL31RA | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL31RA |
Orthologs for IL31RA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IL31RA gene from 3/9 species (see all 9) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
IL31RA1 |
interleukin 31 receptor A |
51.14(n) 36.8(a) |
  |
427140 XM_424732.2 XP_424732.2 |
lizard (Anolis carolinensis) |
Reptilia |
IL31RA6 |
-- |
36(a) |
1 ↔ 1 |
2(2297101-2315620) |
zebrafish (Danio rerio) |
Actinopterygii |
il6st6 |
interleukin 6 signal transducer |
19(a) |
1 → many |
10(7783983-7803832) |
ENSEMBL Gene Tree for IL31RA (if available) TreeFam Gene Tree for IL31RA (if available)  |
Paralogs for IL31RA gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for IL31RA gene
- OSMR2 CSF3R2 IL6ST2 IL27RA2 LIFR2 IL12RB22
IL31RA for paralogs About GeneDecksing
|
Genomic Variants for IL31RA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for IL31RA (55147207 - 55218678 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for IL31RA 1 CNV: 6404 Human Gene Mutation Database (HGMD): IL31RA
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL31RA |
|
Disorders
/ Diseases for IL31RA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IL31RA for disorders About GeneDecksing
OMIM gene information: 609510
OMIM disorders: --
UniProtKB/Swiss-Prot: IL31R_HUMAN, Q8NI17
Defects in IL31RA are the cause of amyloidosis primary localized cutaneous type 2 (PLCA2) [MIM:613955]. PLCA2is primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents withitching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening that may beexacerbated by chronic scratching and rubbing. Primary localized cutaneous amyloidosis is often divided into macularand lichen subtypes although many affected individuals often show both variants coexisting. Lichen amyloidosischaracteristically presents as a pruritic eruption of grouped hyperkeratotic papules with a predilection for theshins, calves, ankles and dorsa of feet and thighs. Papules may coalesce to form hyperkeratotic plaques that canresemble lichen planus, lichen simplex or nodular prurigo. Macular amyloidosis is characterized by small pigmentedmacules that may merge to produce macular hyperpigmentation, sometimes with a reticulate or rippled pattern. Inmacular and lichen amyloidosis, amyloid is deposited in the papillary dermis in association with grouped colloidbodies, thought to represent degenerate basal keratinocytes. The amyloid deposits probably reflect a combination ofdegenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins 17 diseases for IL31RA: About MalaCardsmycobacterium avium complex disease phototoxic dermatitis primary cutaneous amyloidosis lichen planus amyloidosis systemic lupus erythematosus atopic dermatitis antiphospholipid syndrome dermatitis lupus erythematosus hepatitis b hepatitis schizophrenia tuberculosis thyroiditis leukemia prostatitis 3 diseases from the University of Copenhagen DISEASES database for IL31RA:Antiphospholipid syndrome Mycobacterium avium complex disease Systemic lupus erythematosus Human Genome Epidemiology (HuGE) Navigator: IL31RA (3 documents) Export disorders for IL31RA gene to outside databases
|
Publications for IL31RA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IL31RA gene, integrated from 9 sources (see all 23): (articles sorted by number of sources associating them with IL31RA) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5. (PubMed id 11877449)1, 2, 3, 9 Ghilardi N.... De Sauvage F.J. (2002)
- Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. (PubMed id 15184896)1, 2, 3 Dillon S.R.... Gross J.A. (2004)
- Characterization of the signaling capacities of the novel gp130-like cytokine receptor. (PubMed id 15194700)1, 2, 9 Dreuw A....Hermanns H.M. (2004)
- Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis. (PubMed id 19690585)1, 2, 9 Lin M.W....Tsai S.F. (2010)
- IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis. (PubMed id 16461143)1, 2, 9 Bilsborough J.... Gross J.A. (2006)
- Predominant expression of the long isoform of GP130-like (GPL) receptor is required for interleukin-31 signaling. (PubMed id 15627637)1, 2, 9 Diveu C.... Chevalier S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
- GPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor. (PubMed id 14504285)1, 2 Diveu C.... Morel A. (2003)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
|
External Searches for IL31RA gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing IL31RA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IL31RA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IL31RA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for IL31RA | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IL31RA gene: Search GeneIP for patents involving IL31RA
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for IL31RA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for IL31RA | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IL31RA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL31RA | | OriGene Protein Over-expression Lysate for IL31RA | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for IL31RA | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL31RA | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for IL31RA | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for IL31RA | | OriGene Custom Protein Services for IL31RA | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IL31RA | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL31RA | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL31RA | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL31RA | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL31RA | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL31RA |
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| | | Search Tocris compounds for IL31RA |
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 | | IL31RA Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL31RA |
|  |  |  | | | Search ThermoFisher Antibodies for IL31RA |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL31RA |
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