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Aliases for IL31RA Gene

Aliases for IL31RA Gene

  • Interleukin 31 Receptor A 2 3 5
  • Gp130-Like Monocyte Receptor 3 4
  • IL-31 Receptor Subunit Alpha 3 4
  • Cytokine Receptor-Like 3 3 4
  • IL-31R Subunit Alpha 3 4
  • ZcytoR17 3 4
  • IL-31RA 3 4
  • HGLM-R 3 4
  • GLM-R 3 4
  • CRL3 3 4
  • GPL 3 4
  • Interleukin-31 Receptor Subunit Alpha 3
  • Soluble Type I Cytokine Receptor CRL3 3
  • Class I Cytokine Receptor 3
  • Gp130-Like Receptor 4
  • IL-31R-Alpha 4
  • PRO21384 3
  • PLCA2 3
  • GLMR 3
  • CRL 3

External Ids for IL31RA Gene

Previous GeneCards Identifiers for IL31RA Gene

  • GC00U913999
  • GC05P055165
  • GC05P055185
  • GC05P052122
  • GC05P055851

Summaries for IL31RA Gene

Entrez Gene Summary for IL31RA Gene

  • The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

GeneCards Summary for IL31RA Gene

IL31RA (Interleukin 31 Receptor A) is a Protein Coding gene. Diseases associated with IL31RA include Amyloidosis, Primary Localized Cutaneous, 2 and Primary Cutaneous Amyloidosis. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. GO annotations related to this gene include protein kinase binding and cytokine receptor activity. An important paralog of this gene is IL6ST.

UniProtKB/Swiss-Prot for IL31RA Gene

  • Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).

Gene Wiki entry for IL31RA Gene

Additional gene information for IL31RA Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IL31RA Gene

Genomics for IL31RA Gene

Regulatory Elements for IL31RA Gene

Enhancers for IL31RA Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H055902 1.4 FANTOM5 Ensembl ENCODE 11.5 +63.4 63372 1 HDGF PKNOX1 BACH1 EBF1 BATF RELA FOSL1 POLR2A EED ZNF207 IL31RA RNA5SP183 SLC38A9 DDX4 ENSG00000262211 GC05P055845
GH05H055923 1.1 Ensembl ENCODE dbSUPER 11.4 +83.2 83167 1 ZNF687 JUN ZNF175 GABPA POLR2A IKZF1 EED ZBTB33 IKZF2 IL31RA IL6ST FLJ31104 RNA5SP183 SLC38A9 DDX4 ENSG00000262211 GC05P055845
GH05H055711 1.1 ENCODE 10.7 -127.9 -127910 1 HDGF PKNOX1 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 ZNF207 ZNF143 DDX4 IL31RA DHX29 SKIV2L2 SLC38A9 RNA5SP183 GC05P055648
GH05H055897 0.9 Ensembl ENCODE 11.4 +57.5 57496 1 IRF2 NR2F1 MNT ZFHX2 JUND POLR2A EGR1 ZNF512 IKZF1 MLLT1 IL31RA RNA5SP183 SLC38A9 DDX4 ENSG00000262211 GC05P055845
GH05H055913 0.6 ENCODE 11.3 +73.3 73341 1 HDGF PKNOX1 BCL11A ATF7 MLLT1 DPF2 ZNF24 BATF IL31RA LINC01948 ENSG00000262211 GC05P055845
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IL31RA on UCSC Golden Path with GeneCards custom track

Genomic Location for IL31RA Gene

Chromosome:
5
Start:
55,840,334 bp from pter
End:
55,922,854 bp from pter
Size:
82,521 bases
Orientation:
Plus strand

Genomic View for IL31RA Gene

Genes around IL31RA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IL31RA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IL31RA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IL31RA Gene

Proteins for IL31RA Gene

  • Protein details for IL31RA Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NI17-IL31R_HUMAN
    Recommended name:
    Interleukin-31 receptor subunit alpha
    Protein Accession:
    Q8NI17
    Secondary Accessions:
    • A6NIF8
    • Q2TBA1
    • Q6EBC3
    • Q6EBC4
    • Q6EBC5
    • Q6EBC6
    • Q6UWL8
    • Q8WYJ0

    Protein attributes for IL31RA Gene

    Size:
    732 amino acids
    Molecular mass:
    82954 Da
    Quaternary structure:
    • Heterodimer with OSMR. Interacts with JAK1 and STAT3.
    SequenceCaution:
    • Sequence=AAS86444.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAS86445.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for IL31RA Gene

neXtProt entry for IL31RA Gene

Post-translational modifications for IL31RA Gene

  • N-glycosylated.
  • Glycosylation at posLast=3737, isoforms=10, 11, 12, 2, 3, 4, 5, 7, 8, 967, isoforms=10, 11, 12, 2, 3, 4, 5, 7, 8, 993, posLast=166166, posLast=187187, isoforms=10, 11, 12, 2, 3, 4, 5, 6, 7, 8, 9277, posLast=283283, posLast=395395, posLast=455455, and isoforms=10, 11, 12, 2, 3, 5, 6, 9504
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Abcam antibodies for IL31RA
  • Cloud-Clone Corp. Antibodies for IL31RA
  • Santa Cruz Biotechnology (SCBT) Antibodies for IL31RA

Protein Products

  • Abcam proteins for IL31RA

No data available for DME Specific Peptides for IL31RA Gene

Domains & Families for IL31RA Gene

Gene Families for IL31RA Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for IL31RA Gene

Suggested Antigen Peptide Sequences for IL31RA Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NI17

UniProtKB/Swiss-Prot:

IL31R_HUMAN :
  • Belongs to the type I cytokine receptor family. Type 2 subfamily.
Family:
  • Belongs to the type I cytokine receptor family. Type 2 subfamily.
genes like me logo Genes that share domains with IL31RA: view

Function for IL31RA Gene

Molecular function for IL31RA Gene

UniProtKB/Swiss-Prot Function:
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
UniProtKB/Swiss-Prot Induction:
Up-regulated in lesional keratinocytes of patients with atopic dermatitis (PubMed:16461143). Up-regulated by IFNG/IFN-gamma (PubMed:11877449, PubMed:14504285, PubMed:15184896, PubMed:21261663, PubMed:18439099). Up-regulated by bacterial lipopolysaccharides (LPS) (PubMed:11877449, PubMed:15184896, PubMed:14504285). Up-regulated by triacylated lipoprotein (Pam3Cys) (PubMed:21261663). Up-regulated by TGFB1/TGF-beta (PubMed:18439099).

Gene Ontology (GO) - Molecular Function for IL31RA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003713 transcription coactivator activity NAS 11877449
GO:0004896 cytokine receptor activity TAS 11877449
GO:0019901 protein kinase binding NAS 11877449
GO:0019955 cytokine binding NAS 11877449
genes like me logo Genes that share ontologies with IL31RA: view
genes like me logo Genes that share phenotypes with IL31RA: view

Human Phenotype Ontology for IL31RA Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for IL31RA Gene

MGI Knock Outs for IL31RA:

Animal Model Products

  • Taconic Biosciences Mouse Models for IL31RA

CRISPR Products

miRNA for IL31RA Gene

miRTarBase miRNAs that target IL31RA

Clone Products

  • Applied Biological Materials Clones for IL31RA
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for IL31RA Gene

Localization for IL31RA Gene

Subcellular locations from UniProtKB/Swiss-Prot for IL31RA Gene

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, presynaptic cell membrane. Cell projection, axon.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IL31RA gene
Compartment Confidence
plasma membrane 5
nucleus 3
mitochondrion 2
extracellular 1
peroxisome 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for IL31RA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005886 plasma membrane TAS --
GO:0009897 external side of plasma membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 11877449
genes like me logo Genes that share ontologies with IL31RA: view

Pathways & Interactions for IL31RA Gene

genes like me logo Genes that share pathways with IL31RA: view

Pathways by source for IL31RA Gene

SIGNOR curated interactions for IL31RA Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for IL31RA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000165 MAPK cascade NAS 11877449
GO:0002067 glandular epithelial cell differentiation IEA --
GO:0002376 immune system process IEA --
GO:0002438 acute inflammatory response to antigenic stimulus IEA --
GO:0006952 defense response NAS 11877449
genes like me logo Genes that share ontologies with IL31RA: view

Drugs & Compounds for IL31RA Gene

(1) Additional Compounds for IL31RA Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with IL31RA: view

Transcripts for IL31RA Gene

Unigene Clusters for IL31RA Gene

Interleukin 31 receptor A:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for IL31RA
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for IL31RA Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17 ^ 18
SP1: - -
SP2: - - - - -
SP3: - - -
SP4: - - - -
SP5: - - -
SP6: -

Relevant External Links for IL31RA Gene

GeneLoc Exon Structure for
IL31RA
ECgene alternative splicing isoforms for
IL31RA

Expression for IL31RA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IL31RA Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IL31RA Gene

This gene is overexpressed in Artery - Aorta (x12.6), Testis (x6.6), Skin - Not Sun Exposed (Suprapubic) (x4.7), and Skin - Sun Exposed (Lower leg) (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for IL31RA Gene



NURSA nuclear receptor signaling pathways regulating expression of IL31RA Gene:

IL31RA

SOURCE GeneReport for Unigene cluster for IL31RA Gene:

Hs.55378

mRNA Expression by UniProt/SwissProt for IL31RA Gene:

Q8NI17-IL31R_HUMAN
Tissue specificity: Expressed in CD14- and CD56-positive blood cells (PubMed:11877449). Expressed in macrophages (PubMed:16461143, PubMed:18439099). Expressed in keratinocytes (PubMed:21261663). Expressed in a subset of dorsal root ganglia neurons (at protein level) (PubMed:24373353). Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin (PubMed:15184896, PubMed:11877449, PubMed:14504285). Expressed in bronchial and alveolar epithelial cells and pulmonary fibroblasts (PubMed:18439099). Detected in all of the myelomonocytic lineage (PubMed:14504285). Isoform 6: Expressed at higher levels in lesional skin compared to healthy skin of atopic dermatitis patients (PubMed:24373353).

Phenotype-based relationships between genes and organs from Gene ORGANizer for IL31RA Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • integumentary
  • nervous
  • urinary
Organs:
Head and neck:
  • cranial nerve
  • ear
  • eye
  • head
Thorax:
  • esophagus
  • heart
  • heart valve
Abdomen:
  • intestine
  • kidney
  • large intestine
  • small intestine
  • stomach
General:
  • peripheral nerve
  • peripheral nervous system
  • skin
genes like me logo Genes that share expression patterns with IL31RA: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and Evidence on tissue expression from TISSUES for IL31RA Gene

Orthologs for IL31RA Gene

This gene was present in the common ancestor of chordates.

Orthologs for IL31RA Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IL31RA 33 34
  • 99.11 (n)
dog
(Canis familiaris)
Mammalia IL31RA 33 34
  • 82.7 (n)
cow
(Bos Taurus)
Mammalia IL31RA 33 34
  • 81.17 (n)
mouse
(Mus musculus)
Mammalia Il31ra 33 16 34
  • 73.51 (n)
rat
(Rattus norvegicus)
Mammalia Il31ra 33
  • 73.14 (n)
oppossum
(Monodelphis domestica)
Mammalia IL31RA 34
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 12 (a)
ManyToMany
chicken
(Gallus gallus)
Aves IL31RA 33
  • 52.54 (n)
lizard
(Anolis carolinensis)
Reptilia IL31RA 34
  • 33 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii il12rb2l 34
  • 14 (a)
ManyToMany
Species where no ortholog for IL31RA was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IL31RA Gene

ENSEMBL:
Gene Tree for IL31RA (if available)
TreeFam:
Gene Tree for IL31RA (if available)

Paralogs for IL31RA Gene

Paralogs for IL31RA Gene

genes like me logo Genes that share paralogs with IL31RA: view

Variants for IL31RA Gene

Sequence variations from dbSNP and Humsavar for IL31RA Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
VAR_065809 Amyloidosis, primary localized cutaneous, 2 (PLCA2) [MIM:613955]
rs1000001735 -- 55,840,409(+) AAGTG(C/T)TGCTA utr-variant-5-prime
rs1000018698 -- 55,887,394(+) TTTGT(A/G)TAATA intron-variant
rs1000026036 -- 55,894,295(+) TGGGA(A/G)GAACT intron-variant
rs1000100039 -- 55,851,862(+) CATTT(C/T)TCTTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for IL31RA Gene

Variant ID Type Subtype PubMed ID
nsv1073883 CNV deletion 25765185
nsv1109698 CNV deletion 24896259
nsv1119033 CNV deletion 24896259
nsv327714 CNV deletion 16902084
nsv474741 CNV novel sequence insertion 20440878
nsv524739 CNV loss 19592680
nsv830307 CNV gain 17160897
nsv950061 CNV deletion 24416366

Variation tolerance for IL31RA Gene

Residual Variation Intolerance Score: 14.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.84; 86.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IL31RA Gene

Human Gene Mutation Database (HGMD)
IL31RA
SNPedia medical, phenotypic, and genealogical associations of SNPs for
IL31RA

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL31RA Gene

Disorders for IL31RA Gene

MalaCards: The human disease database

(9) MalaCards diseases for IL31RA Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
amyloidosis, primary localized cutaneous, 2
  • amyloidosis, primary localized cutaneous 2
primary cutaneous amyloidosis
  • familial primary localized cutaneous amyloidosis
dermatitis
  • eczema
lichen amyloidosis
  • amyloid lichen
macular amyloidosis
  • amyloidosis, macular
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

IL31R_HUMAN
  • Amyloidosis, primary localized cutaneous, 2 (PLCA2) [MIM:613955]: A primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening that may be exacerbated by chronic scratching and rubbing. Primary localized cutaneous amyloidosis is often divided into macular and lichen subtypes although many affected individuals often show both variants coexisting. Lichen amyloidosis characteristically presents as a pruritic eruption of grouped hyperkeratotic papules with a predilection for the shins, calves, ankles and dorsa of feet and thighs. Papules may coalesce to form hyperkeratotic plaques that can resemble lichen planus, lichen simplex or nodular prurigo. Macular amyloidosis is characterized by small pigmented macules that may merge to produce macular hyperpigmentation, sometimes with a reticulate or rippled pattern. In macular and lichen amyloidosis, amyloid is deposited in the papillary dermis in association with grouped colloid bodies, thought to represent degenerate basal keratinocytes. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins. {ECO:0000269 PubMed:19690585}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for IL31RA

Genetic Association Database (GAD)
IL31RA
Human Genome Epidemiology (HuGE) Navigator
IL31RA
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IL31RA
genes like me logo Genes that share disorders with IL31RA: view

No data available for Genatlas for IL31RA Gene

Publications for IL31RA Gene

  1. A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5. (PMID: 11877449) Ghilardi N … de Sauvage FJ (The Journal of biological chemistry 2002) 2 3 4 22 60
  2. Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis. (PMID: 19690585) Lin MW … Tsai SF (European journal of human genetics : EJHG 2010) 3 4 22 60
  3. IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis. (PMID: 16461143) Bilsborough J … Gross JA (The Journal of allergy and clinical immunology 2006) 3 4 22 60
  4. Characterization of the signaling capacities of the novel gp130-like cytokine receptor. (PMID: 15194700) Dreuw A … Hermanns HM (The Journal of biological chemistry 2004) 3 4 22 60
  5. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. (PMID: 15184896) Dillon SR … Gross JA (Nature immunology 2004) 2 3 4 60

Products for IL31RA Gene

Sources for IL31RA Gene

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