Aliases for IL3 Gene
External Ids for IL3 Gene
Previous GeneCards Identifiers for IL3 Gene
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL3 Gene
IL3 (Interleukin 3) is a Protein Coding gene. Diseases associated with IL3 include Eosinophilia and Subcutaneous Mycosis. Among its related pathways are p70S6K Signaling and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. GO annotations related to this gene include cytokine activity and interleukin-3 receptor binding.
UniProtKB/Swiss-Prot for IL3 Gene
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.