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IL2RB Gene

protein-coding   GIFtS: 68
GCID: GC22M037515

Interleukin 2 Receptor, Beta

(Previous names: interleukin 15 receptor, beta)
(Previous symbol: IL15RB)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Interleukin 2 Receptor, Beta1 2     IL-2R Subunit Beta2 3
IL15RB1 2     p752 3
Interleukin 15 Receptor, Beta1 2     CD1222
High Affinity IL-2 Receptor Subunit Beta2 3     P70-752
IL-2RB2 3     High Affinity IL-2 Receptor Beta Subunit2
CD122 Antigen2 3     Interleukin-2 Receptor Subunit Beta2
IL-2 Receptor Subunit Beta2 3     p70-753

External Ids:    HGNC: 60091   Entrez Gene: 35602   Ensembl: ENSG000001003857   OMIM: 1467105   UniProtKB: P147843   
ORGUL members:         

Export aliases for IL2RB gene to outside databases

Previous GC identifers: GC22M034136 GC22M035764 GC22M035846 GC22M020487


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IL2RB Gene:
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with
respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not
involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer,
while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high
affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic
signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane
protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for IL2RB Gene:
IL2RB (interleukin 2 receptor, beta) is a protein-coding gene. Diseases associated with IL2RB include orchitis, and occipital neuralgia. GO annotations related to this gene include interleukin-2 receptor activity and interleukin-2 binding.

UniProtKB/Swiss-Prot: IL2RB_HUMAN, P14784
Function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and
transduces the mitogenic signals of IL2

Gene Wiki entry for IL2RB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the IL2RB gene promoter:
         Elk-1   GATA-3   STAT5A   GATA-2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL2RB promoter sequence
   Search Chromatin IP Primers for IL2RB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IL2RB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q12.3   HGNC cytogenetic band: 22q13

IL2RB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL2RB gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M037515:  view genomic region     (about GC identifiers)

Start:
37,521,878 bp from pter      End:
37,571,094 bp from pter
Size:
49,217 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IL2RB_HUMAN, P14784 (See protein sequence)
Recommended Name: Interleukin-2 receptor subunit beta precursor  
Size: 551 amino acids; 61117 Da
Subunit: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity
dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and
intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.
Interacts with HTLV-1 accessory protein p12I
6 PDB 3D structures from and Proteopedia for IL2RB:
1ILM (3D)        1ILN (3D)        2B5I (3D)        2ERJ (3D)        3QAZ (3D)        4GS7 (3D)    
Secondary accessions: B2R765

Explore the universe of human proteins at neXtProt for IL2RB: NX_P14784

Explore proteomics data for IL2RB at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn29, Asn43, Asn71, Asn149
  • Modification sites at PhosphoSitePlus

  • See IL2RB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000869.1  
    ENSEMBL proteins: 
     ENSP00000216223   ENSP00000403731   ENSP00000402685   ENSP00000400416   ENSP00000401020  
    Reactome Protein details: P14784

    IL2RB Human Recombinant Protein Products:

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    Novus Biologicals IL2RB Lysates
    Sino Biological Recombinant Protein for IL2RB
    Sino Biological Cell Lysate for IL2RB
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    Browse Proteins at Cloud-Clone Corp.

    IL2RB Antibody Products:

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    Novus Biologicals IL2RB Antibodies
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    IL2RB Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    IL: Interleukins and interleukin receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: Interleukin-2 receptor beta subunit
    IL-2 receptor family

    3 InterPro protein domains:
     IPR003961 Fibronectin_type3
     IPR013783 Ig-like_fold
     IPR003531 Hempt_rcpt_S_F1_CS

    Graphical View of Domain Structure for InterPro Entry P14784

    ProtoNet protein and cluster: P14784

    1 Blocks protein domain: IPB003531 Short hematopoietin receptor

    UniProtKB/Swiss-Prot: IL2RB_HUMAN, P14784
    Domain: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular
    transport and cell-surface receptor binding
    Domain: The box 1 motif is required for JAK interaction and/or activation
    Similarity: Belongs to the type I cytokine receptor family. Type 4 subfamily
    Similarity: Contains 1 fibronectin type-III domain


    IL2RB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IL2RB_HUMAN, P14784
    Function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and
    transduces the mitogenic signals of IL2

         Genatlas biochemistry entry for IL2RB:
    interleukin 2,high affinity receptor,beta chain 70-75kDa,hematopoietic receptor family,expressed in various
    tissues

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004911contributes to interleukin-2 receptor activity TAS2467293
    GO:0005515protein binding ----
    GO:0019976interleukin-2 binding ISS--
         
    IL2RB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IL2RB:
     Synthetic lethal with Ras 

         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Il2rb):
     behavior/neurological  embryogenesis  endocrine/exocrine gland  growth/size/body  hematopoietic system 
     immune system  integument  liver/biliary system  mortality/aging  reproductive system 

    IL2RB for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Il2rbtm1Mak for IL2RB

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IL2RB
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IL2RB
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IL2RB

    miRNA
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    Block miRNA regulation of human, mouse, rat IL2RB using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IL2RB (see all 11):
    hsa-miR-146b-3p hsa-miR-15a hsa-miR-497 hsa-miR-424 hsa-miR-24 hsa-miR-195 hsa-miR-16 hsa-miR-15b
    SwitchGear 3'UTR luciferase reporter plasmidIL2RB 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat IL2RB

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for IL2RB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IL2RB (NM_000878)
    Sino Biological Human cDNA Clone for IL2RB
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL2RB


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IL2RB_HUMAN, P14784: Membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    endoplasmic reticulum1
    extracellular1
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS8514792
    GO:0009897external side of plasma membrane ISS--

    IL2RB for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IL2RB About   (see all 27)  
    See pathways by source

    SuperPathContained pathways About
    1PEDF Induced Signaling
    NFAT Signaling and Lymphocyte Interactions0.57
    Glucocorticoid Receptor Signaling0.43
    PGC1Alpha Pathway0.51
    Cytokine-cytokine receptor interaction0.43
    STAT3 Pathway0.47
    2IL2-mediated signaling events
    IL-2 Signaling pathway0.49
    IL2-mediated signaling events0.49
    3TGF-Beta Pathway
    TGF-Beta Pathway0.60
    JAK-STAT Pathway0.57
    MAPK Family Pathway0.60
    JNK Pathway0.51
    4Signaling by Interleukins
    Interleukin receptor SHC signaling0.67
    Interleukin-3, 5 and GM-CSF signaling0.59
    Interleukin-2 signaling0.67
    Signaling by Interleukins0.42
    5Akt Signaling
    Akt Signaling0.60
    Tec Kinases Signaling0.55
    p38 Signaling0.60

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    4 R&D Systems Pathways for IL2RB
        IL-2 Signaling Pathways
    IL-15 Signaling Pathways
    IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types
    IL-2 Signaling and its Primary Biological Effects in Different Immune Cell Types

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IL2RB (see all 15)
        STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    Glucocorticoid Receptor Signaling
    ICos-ICosL Pathway in T-Helper Cell

    2 Cell Signaling Technology (CST) Pathways for IL2RB
        Lymphocyte Signaling
    Tyrosine Kinases / Adaptors

    2 GeneGo (Thomson Reuters) Pathways for IL2RB
        Immune response IL-22 signaling pathway
    Immune response IL-2 activation and signaling pathway

    Selected BioSystems Pathways for IL2RB (see all 8)
        IL-5 Signaling Pathway
    IL-2 Signaling pathway
    IL2 signaling events mediated by PI3K
    IL2-mediated signaling events
    IL12-mediated signaling events


    2 Reactome Pathways for IL2RB
        Interleukin receptor SHC signaling
    Interleukin-2 signaling


    Selected Kegg Pathways  (Kegg details for IL2RB) (see all 7):
        Cytokine-cytokine receptor interaction
    Endocytosis
    PI3K-Akt signaling pathway
    Jak-STAT signaling pathway
    Measles


    IL2RB for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including IL2RB: 
              Interferons & Receptors in human mouse rat
              Inflammatory Cytokines & Receptors in human mouse rat
              T-Cell Anergy & Immune Tolerance in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for IL2RB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for IL2RB (P147842, 3 ENSP000002162234) via UniProtKB, MINT, STRING, and/or I2D (see all 91)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STAT5AP422292, 3, ENSP000003412084MINT-8035160 I2D: score=4 STRING: ENSP00000341208
    STAT5BP516922, 3, ENSP000002933284MINT-8035171 I2D: score=4 STRING: ENSP00000293328
    SHBQ154642, 3, ENSP000003669364MINT-8035186 I2D: score=3 STRING: ENSP00000366936
    GNB2L1P632443, ENSP000003660134I2D: score=4 STRING: ENSP00000366013
    SHC1P293533, ENSP000004013034I2D: score=4 STRING: ENSP00000401303
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    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006461protein complex assembly TAS2467293
    GO:0007165signal transduction TAS2785715
    GO:0016032viral process IEA--
    GO:0019048modulation by virus of host morphology or physiology ----
    GO:0019221cytokine-mediated signaling pathway IDA7736574

    IL2RB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IL2RB

    4 DrugBank Compounds for IL2RB    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    AldesleukinIL-2 (see all 4)85898-30-2targetagonist modulator16542139 16617454 16569767 11752352 16477002 16596189
    Basiliximabchimeric mouse-human antiCD25 (see all 2)152923-56-3targetantibody11840795 11752352 12826150 10188761 12667677 10708100
    DaclizumabAnti-IL-2 (see all 3)152923-56-3targetantibody15022409 2571203 11752352 2647626 12372041 15814281
    Denileukin diftitoxDiphtheria toxin precursor (see all 3)173146-27-5targetagonist16516670 15811959 11752352 17187516 18684057

    Selected Novoseek inferred chemical compound relationships for IL2RB gene (see all 118)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    daclizumab 75.5 25 11359452 (2), 20415630 (2), 9794841 (1), 11004222 (1) (see all 21)
    neopterin 74.5 56 9892527 (5), 7647844 (3), 17975200 (2), 1606739 (2) (see all 41)
    okt3 66.8 13 2148645 (2), 2121373 (2), 1916932 (1), 8027539 (1) (see all 9)
    denileukin diftitox 65.3 12 15353540 (1), 19707452 (1), 16410787 (1), 18295790 (1) (see all 6)
    basiliximab 62.4 14 12667677 (2), 11840795 (2), 10188761 (1), 17150025 (1) (see all 10)
    cyclosporin a 58.7 30 1864010 (2), 1864013 (1), 1346344 (1), 7509146 (1) (see all 26)
    r-il-2 53.8 1 7576120 (1)
    thymoglobulin 53.4 7 15041353 (1), 15575919 (1), 17927304 (1), 19236436 (1) (see all 7)
    ionomycin 50.8 5 8344700 (1), 1654606 (1), 2017664 (1), 11347470 (1) (see all 5)
    tyrosine 50.4 68 1639773 (3), 8089104 (3), 2007186 (3), 7612266 (2) (see all 50)



    IL2RB for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IL2RB gene: 
    NM_000878.3  

    Unigene Cluster for IL2RB:

    Interleukin 2 receptor, beta
    Hs.474787  [show with all ESTs]
    Unigene Representative Sequence: NM_000878
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216223(uc003aqv.1) ENST00000483573 ENST00000453962 ENST00000429622
    ENST00000461607 ENST00000440958 ENST00000445595
    miRNA
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    hsa-miR-146b-3p hsa-miR-15a hsa-miR-497 hsa-miR-424 hsa-miR-24 hsa-miR-195 hsa-miR-16 hsa-miR-15b
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat IL2RB
      QuantiFast Probe-based Assays in human, mouse, rat IL2RB

    Additional mRNA sequence: 

    AK312860.1 BC025691.1 CR456506.1 M26062.1 

    7 DOTS entries:

    DT.312677  DT.120651820  DT.120651728  DT.120651741  DT.91695341  DT.65286096  DT.91692959 

    Selected AceView cDNA sequences (see all 209):

    BX378224 H55712 BQ707555 NM_182486 BQ053622 AL708630 CR606760 BC025691 
    AI968918 BQ008149 BQ053441 CR456506 AK128125 BF223041 T28565 H55257 
    BM722009 BX339049 CD633231 AI989994 H55722 M26062 BU859813 NM_000878 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for IL2RB    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10
    SP1:                          -                       -                                             
    SP2:                          -           -     -     -     -                                       
    SP3:                          -                                                                     
    SP4:                                                                                                


    ECgene alternative splicing isoforms for IL2RB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

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    IL2RB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCCTCCTG
    IL2RB Expression
    About this image


    IL2RB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 3 entries
             Natural Killer Cells Peripheral Blood
     
     Thymus (Hematopoietic System)    fully expand to see all 3 entries
             T Helper Cells Thymus
             Thymus
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Spleen (Hematopoietic System)
    IL2RB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IL2RB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.474787
        Pathway & Disease-focused RT2 Profiler PCR Arrays including IL2RB: 
              Interferons & Receptors in human mouse rat
              Inflammatory Cytokines & Receptors in human mouse rat
              T-Cell Anergy & Immune Tolerance in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for IL2RB
    OriGene qSTAR qPCR primer pairs in human, mouse for IL2RB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IL2RB
    QuantiTect SYBR Green Assays in human, mouse, rat IL2RB
    QuantiFast Probe-based Assays in human, mouse, rat IL2RB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL2RB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IL2RB gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Il2rb1 , 5 interleukin 2 receptor, beta chain1, 5 71.04(n)1
    59.36(a)1
      15 (37.52 cM)5
    161851  NM_008368.41  NP_032394.11 
     784805535 
    chicken
    (Gallus gallus)
    Aves IL2RB6
    interleukin 2 receptor, beta
    31(a)
    1 ↔ 1
    1(51302272-51314508)
    lizard
    (Anolis carolinensis)
    Reptilia IL2RB6
    interleukin 2 receptor, beta
    25(a)
    1 ↔ 1
    5(22752570-22783364)
    zebrafish
    (Danio rerio)
    Actinopterygii il2rb6
    interleukin 2 receptor, beta
    21(a)
    1 ↔ 1
    3(25292633-25310273) ENSDARG00000075720


    ENSEMBL Gene Tree for IL2RB (if available)
    TreeFam Gene Tree for IL2RB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IL2RB gene

    IL2RB for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for IL2RB
    PGOHUM00000250326


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IL2RB (see all 720)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs32183361,2
    C,F,H--37521478(-) CCAGAC/TCAGGG 1 -- ds50016Minor allele frequency- T:0.01NS EA 504
    rs1451375261,2
    --37521544(+) GGGGG-/ATAGAG 1 -- ds50010--------
    rs588099631,2
    C--37521546(+) TAGAG-/A/GAG 
     
    /GAGAGG
    GGGGG
    3 -- ds5001 cds10--------
    rs2015612361,2
    --37521548(+) GATAG-/AGGGGG 1 -- ds50010--------
    rs1468544241,2
    C--37521646(+) TATTT-/CCCCAG 1 -- ds50010--------
    rs32183351,2
    C,F--37521662(-) TCCCAC/TAAGTC 1 -- ds50012Minor allele frequency- T:0.01NS 82
    rs1862350861,2
    --37521670(+) GGATAA/TGGCCA 1 -- ds50010--------
    rs1889496841,2
    --37521802(+) GTCTTC/TGACAG 1 -- ds50010--------
    rs1813940081,2
    --37521838(+) TTTAAG/TAGACA 1 -- ds50010--------
    rs1858205031,2
    C--37521859(+) CGCAGA/GCAATG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for IL2RB (37521878 - 37571094 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for IL2RB:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv34015CNV Loss18971310
    nsv829203CNV Loss20364138
    nsv915016CNV Loss21882294
    nsv834187CNV Loss17160897
    nsv915017CNV Gain21882294
    nsv459882CNV Gain19166990

    Human Gene Mutation Database (HGMD): IL2RB
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IL2RB
    DNA2.0 Custom Variant and Variant Library Synthesis for IL2RB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 146710    OMIM disorders: --

    Selected diseases for IL2RB (see all 176):    
    About MalaCards
    orchitis    occipital neuralgia    granulomatous orchitis    berylliosis
    polymyalgia rheumatica    extramedullary plasmacytoma    kikuchi disease    acute graft versus host disease
    primary malignant lymphoma    central pontine myelinolysis    posterior uveitis    mycosis fungoides
    oligoarticular juvenile arthritis    polyarticular onset juvenile idiopathic arthritis    intravascular large b-cell lymphoma    t-lymphocytopenia
    dermatitis herpetiformis    panniculitis    hematologic cancer    herpes simplex encephalitis


    IL2RB for disorders           About GeneDecksing

    Selected Novoseek inferred disease relationships for IL2RB gene (see all 94)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    severe combined immunodeficiency, x-linked 72.6 11 16138102 (1), 7718508 (1), 7523745 (1), 7632950 (1) (see all 9)
    necrosis 63.9 160 11505128 (2), 1910217 (2), 9060545 (2), 8146526 (2) (see all 99)
    tumors 50 172 16996570 (3), 8146526 (3), 10685665 (3), 11505128 (2) (see all 99)
    autoimmune diseases 48.2 17 1934612 (1), 8580481 (1), 15528977 (1), 2081786 (1) (see all 17)
    leukemia hairy cell 47.8 5 2072745 (1), 8107487 (1), 8329708 (1), 1700727 (1) (see all 5)
    leukemia t-cell 45.9 6 8102412 (1), 1379847 (1), 2298500 (1), 8648694 (1) (see all 5)
    diphtheria 45.7 7 15353540 (1), 16586495 (1), 9796831 (1), 16410787 (1) (see all 7)
    metastatic melanoma 41.9 1 10711641 (1)
    htlv-i infections 41.8 1 1982452 (1)
    rheumatoid arthritis 41.4 15 2289327 (2), 7738942 (2), 8039284 (2), 7921769 (1) (see all 12)

    Genetic Association Database (GAD): IL2RB
    Human Genome Epidemiology (HuGE) Navigator: IL2RB (39 documents)

    Export disorders for IL2RB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IL2RB gene, integrated from 10 sources (see all 1217) (see top 10):
    (articles sorted by number of sources associating them with IL2RB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. (PubMed id 16477002)1, 2, 7 Stauber D.J.... Wilson I.A. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    2. IL-2 receptor signaling through the Shb adapter protein in T and NK cells. (PubMed id 12200137)1, 2, 9 Lindholm C.K. (Biochem. Biophys. Res. Commun. 2002)
    3. Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis. (PubMed id 17108990)1, 4, 9 Bucheton B....Dessein A.J. (Genes Immun. 2007)
    4. IL-2 gene C/T polymorphism is associated with prostate cancer. (PubMed id 17115417)1, 4, 9 Wu H.C....Chen W.C. (J. Clin. Lab. Anal. 2006)
    5. The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface. (PubMed id 8648694)1, 2, 9 Mulloy J.C.... Franchini G. (J. Virol. 1996)
    6. Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways. (PubMed id 21653640)1, 4 Eleftherohorinou H....Coin L.J. (Hum. Mol. Genet. 2011)
    7. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. (PubMed id 21829393)1, 4 Plagnol V....Todd J.A. (PLoS Genet. 2011)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    9. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626)1, 4 Hildebrandt M.A....Wu X. (PLoS ONE 2010)
    10. Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. (PubMed id 20498205)1, 4 Plant D....Worthington J. (Ann. Rheum. Dis. 2010)
    11. A novel galectin-1 and interleukin 2 receptor I^ haplotype is associated with autoimmune myasthenia gravis. (PubMed id 20728947)1, 4 PA!l Z....BuzA!s E.I. (J. Neuroimmunol. 2010)
    12. A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis. (PubMed id 20049410)1, 4 Wieczorek S....Epplen J.T. (J. Mol. Med. 2010)
    13. Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. (PubMed id 20140262)1, 4 Ryckman K.K....Jacobsson B. (PLoS ONE 2010)
    14. Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk. (PubMed id 20179739)1, 4 Cavanillas M.L....Urcelay E. (Eur. J. Hum. Genet. 2010)
    15. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    16. A large-scale, consortium-based genomewide association study of asthma. (PubMed id 20860503)1, 4 Moffatt M.F....Cookson W.O. (N. Engl. J. Med. 2010)
    17. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
    18. L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. (PubMed id 20424473)1, 4 Yokoyama K....Hosoya T. (Nephron Clin Pract 2010)
    19. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
    20. Interleukin-2 receptor beta gene C627T polymorphism in Korean women with endometriosis: a case-control study. (PubMed id 19602517)1, 4 Lee G.H....Moon S.Y. (Hum. Reprod. 2009)
    21. Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients. (PubMed id 19817957)1, 4 Segat L....Crovella S. (J. Gastroenterol. Hepatol. 2009)
    22. Novel association of the interleukin 2-interleukin 21 region with inflammatory bowel disease. (PubMed id 19471255)1, 4 MA!rquez A....Urcelay E. (Am. J. Gastroenterol. 2009)
    23. Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (amp 2009)
    24. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (Gut 2009)
    25. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (Am. J. Obstet. Gynecol. 2009)
    26. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. (PubMed id 19773451)1, 4 Reyes-Gibby C.C....Shete S. (amp 2009)
    27. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (PLoS ONE 2008)
    28. Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population. (PubMed id 18715339)1, 4 Dhiman N....Poland G.A. (Tissue Antigens 2008)
    29. Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. (PubMed id 18774388)1, 4 Tremblay K....Laprise C. (J. Allergy Clin. Immunol. 2008)
    30. Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes. (PubMed id 17152005)1, 4 Dhiman N....Jacobson R.M. (J. Infect. Dis. 2007)
    31. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (J. Infect. Dis. 2007)
    32. Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. (PubMed id 16293754)1, 2 Wang X.... Garcia K.C. (Science 2005)
    33. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. (PubMed id 16380905)1, 4 Fallin M.D....Pulver A.E. (Am. J. Hum. Genet. 2005)
    34. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    35. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    36. Genetic variations in humans associated with differences in the course of hepatitis C. (PubMed id 15063762)1, 4 Saito T....Kawata S. (Biochem. Biophys. Res. Commun. 2004)
    37. Chagas' disease susceptibility/resistance: linkage disequilibrium analysis suggests epistasis between major histocompatibility complex and interleukin-10. (PubMed id 15191519)1, 4 Moreno M....Arcos-Burgos M. (Tissue Antigens 2004)
    38. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    39. The interleukin-2 and interleukin-4 receptors studied by molecular modelling. (PubMed id 7529123)1, 2 Bamborough P.... Richards W.G. (Structure 1994)
    40. Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's. (PubMed id 2785715)1, 2 Hatakeyama M.... Taniguchi T. (Science 1989)
    41. Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production. (PubMed id 11238664)1, 9 Corrigall V.M....Panayi G.S. (J. Immunol. 2001)
    42. Interleukin-2 (IL-2) induces tyrosine kinase-dependent translocation of active raf-1 from the IL-2 receptor into the cytosol. (PubMed id 1639773)1, 9 Maslinski W....Strom T.B. (J. Biol. Chem. 1992)
    43. Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains of the IL-2 receptor beta chain. (PubMed id 10602027)1, 9 Delespine-Carmagnat M....Bertoglio J. (Eur. J. Immunol. 2000)
    44. Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system. (PubMed id 12667677)7, 9 WarlAc M.C....Metselaar H.J. (J. Immunol. Methods 2003)
    45. [Immune suppression by combination therapy with basiliximab and cyclosporin in high risk keratoplasty. A pilot study]. (PubMed id 11840795)7, 9 Schmitz K....Behrens-Baumann W. (Ophthalmologe 2002)
    46. Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation. (PubMed id 9774657)1, 9 Migone T.S....Leonard W.J. (Mol. Cell. Biol. 1998)
    47. Optimizing denileukin diftitox (Ontak) therapy. (PubMed id 18684057)7, 9 Duvic M. and Talpur R. (Future Oncol 2008)
    48. Clinical experience with denileukin diftitox (ONTAK). (PubMed id 16516670)7, 9 Foss F. (Semin. Oncol. 2006)
    49. Airway inflammation in asymptomatic children with episodic wheeze. (PubMed id 16617454)7, 9 Maclennan C....Freezer N.J. (Pediatr. Pulmonol. 2006)
    50. Differential regulation of T-cell growth by IL-2 and IL-15. (PubMed id 16569767)7, 9 Cornish G.H....Cantrell D.A. (Blood 2006)
    51. [New immunological weapons for medicine in the 21st Century: biological therapy based on the use of the latest generation monoclonal antibodies]. (PubMed id 15022409)7, 9 AguillA^n J.C....Cuchacovich M. (Rev Med Chil 2003)
    52. SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation. (PubMed id 10373548)1, 9 Cohney S.J....Johnston J.A. (Mol. Cell. Biol. 1999)
    53. Basiliximab. (PubMed id 10188761)7, 9 Onrust S.V. and Wiseman L.R. (Drugs 1999)
    54. Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta. (PubMed id 9553136)1, 9 Zhu M.H....Leonard W.J. (J. Biol. Chem. 1998)
    55. Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells. (PubMed id 9520455)1, 9 Migone T.S....Johnston J.A. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    56. Interleukin-15 signals T84 colonic epithelial cells in the absence of the interleukin-2 receptor beta-chain. (PubMed id 9176231)1, 9 Stevens A.C....Maslinski W. (Am. J. Physiol. 1997)
    57. Interleukin-2 receptor beta and gamma chain dysregulation during the inhibition of CD4 T cell activation by human immunodeficiency virus-1 gp120. (PubMed id 9341758)1, 9 Bani L....ThA"ze J. (Eur. J. Immunol. 1997)
    58. Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. (PubMed id 8700888)1, 9 Friedmann M.C....Leonard W.J. (Proc. Natl. Acad. Sci. U.S.A. 1996)
    59. Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. (PubMed id 7600304)1, 9 Minami Y....Taniguchi T. (Immunity 1995)
    60. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. (PubMed id 7973659)1, 9 Miyazaki T....Ihle J.N. (Science 1994)
    61. Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains. (PubMed id 8041779)1, 9 Tanaka N....Sugamura K. (Proc. Natl. Acad. Sci. U.S.A. 1994)
    62. The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation. (PubMed id 8294403)1, 9 Ravichandran K.S. and Burakoff S.J. (J. Biol. Chem. 1994)
    63. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. (PubMed id 8026467)1, 9 Giri J.G....Anderson D. (EMBO J. 1994)
    64. Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit. (PubMed id 7693677)1, 9 Kirken R.A....Farrar W.L. (J. Biol. Chem. 1993)
    65. Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated. (PubMed id 2303462)1, 9 Mills G.B....Greene W.C. (J. Biol. Chem. 1990)
    66. Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors. (PubMed id 23418630)1 Pekalski M.L....Wicker L.S. (J. Immunol. 2013)
    67. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. (PubMed id 23341462)1 Rodriguez G....Kirken R.A. (J. Biol. Chem. 2013)
    68. Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition. (PubMed id 23676143)1 CAcnit M.C....MartA-n J. (BMC Med. Genet. 2013)
    69. Chimeric I^c cytokine receptors confer cytokine independent engraftment of human T lymphocytes. (PubMed id 23628622)1 Hunter M.R....Jensen M.C. (Mol. Immunol. 2013)
    70. Lack of association of IL-2RA and IL-2RB polymorphisms with rheumatoid arthritis in a Han Chinese population. (PubMed id 23512675)1 Zhu J....Zhou B. (Genet. Mol. Res. 2013)
    71. Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. (PubMed id 22573796)1 Spitz M.R....Amos C.I. (amp 2012)
    72. Soluble cytokine receptors (sIL-2RI+, sIL-2RI^) induce subunit-specific behavioral responses and accumulate in the cerebral cortex and basal forebrain. (PubMed id 22558434)1 Zalcman S.S....Siegel A. (PLoS ONE 2012)
    73. The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register. (PubMed id 20219786)1 Plant D....Barton A. (Rheumatology (Oxford) 2011)
    74. Impact of IL2 and IL2RB genetic polymorphisms in kidney transplantation. (PubMed id 21839273)1 Park S.J....Kim Y.H. (Transplant. Proc. 2011)
    75. The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development. (PubMed id 21984699)1 Castro I....Malek T.R. (J. Immunol. 2011)
    76. Placenta-specific expression of the interleukin-2 (IL-2) receptor I^ subunit from an endogenous retroviral promoter. (PubMed id 21865161)1 Cohen C.J....Mager D.L. (J. Biol. Chem. 2011)
    77. Genetic variation at 5 new autosomal short tandem repeat markers (D10S1248, D22S1045, D2S441, D1S1656, D12S391) in a population-based sample from Maghreb region. (PubMed id 21674833)1 Cortellini V....Verzeletti A. (Croat. Med. J. 2011)
    78. Peripherally induced human regulatory T cells uncouple Kv1.3 activation from TCR-associated signaling. (PubMed id 21834013)1 Reneer M.C....Marti F. (Eur. J. Immunol. 2011)
    79. Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting. (PubMed id 21362618)1 Amano Y....Takeshita T. (J. Biol. Chem. 2011)
    80. Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells. (PubMed id 21345943)1 Shuh M....Derse D. (J. Virol. 2011)
    81. Ectodomain shedding of interleukin-2 receptor beta and generation of an intracellular functional fragment. (PubMed id 20495002)1 Montes de Oca P....Gesbert F. (J. Biol. Chem. 2010)
    82. ZNF300, a recently identified human transcription factor, activates the human IL-2RI^ promoter through the overlapping ZNF300/EGR1 binding site. (PubMed id 20585888)1 Xue L....Li W. (amp 2010)
    83. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (Transplantation 2010)
    84. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    85. Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation. (PubMed id 19923221)1 Ross J.A....Kirken R.A. (J. Biol. Chem. 2010)
    86. Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans. (PubMed id 21120996)4 Hughes L.B....Bridges S.L. (Arthritis Rheum. 2010)
    87. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    88. In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein. (PubMed id 18791162)1 Fukumoto R....Franchini G. (Blood 2009)
    89. Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population. (PubMed id 19822714)1 Kurreeman F.A....Toes R.E. (Ann. Rheum. Dis. 2009)
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    221. Maternal serum levels of tumor necrosis factor-alpha and interleukin-2 receptor in threatened abortion: a comparison with normal and pathologic pregnancies. (PubMed id 11591402)9 GA1cer F....Yardim T. (Fertil. Steril. 2001)
    222. Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a. (PubMed id 11340297)9 Brockdorff J.L....A9dum N. (Exp. Clin. Immunogenet. 2001)
    223. Relationship of hypolipidemia to cytokine concentrations and outcomes in critically ill surgical patients. (PubMed id 11505128)9 Gordon B.R....Rubin A.L. (Crit. Care Med. 2001)
    224. Inflammatory mediators in umbilical plasma from neonates who develop early-onset sepsis. (PubMed id 11474148)9 DA...Austgulen R. (Biol. Neonate 2001)
    225. CD122 (interleukin-2 receptor beta subunit). (PubMed id 11388752)9 Zamai L....Papa S. (J. Biol. Regul. Homeost. Agents 2001)
    226. Serum and ascites fluid cytokine levels in patients with chronic heart failure. (PubMed id 11573826)9 Sari R....Hilmioglu F. (Acta Cardiol 2001)
    227. Complex perioperative immuno-dysfunction in patients with renal cell carcinoma. (PubMed id 11490228)9 BAPhm M....Allhoff E.P. (J. Urol. 2001)
    228. The predictive value of serum interleukins in recurrent respiratory papillomatosis: a preliminary study. (PubMed id 11224768)9 Snowden R.T....Stocks R.M. (Laryngoscope 2001)
    229. T cells activate the tumor necrosis factor-alpha system during hemodialysis, resulting in tachyphylaxis. (PubMed id 11231343)9 van Riemsdijk I.C....Weimar W. (Kidney Int. 2001)
    230. Interleukin 2 modulates ion secretion and cell proliferation in cultured human small intestinal enterocytes. (PubMed id 11600465)9 O'Loughlin E.V....Clancy R. (Gut 2001)
    231. Elevated plasma levels of interleukin-2 and soluble IL-2 receptor in ischemic heart disease. (PubMed id 11288973)9 Simon A.D....Rabbani L.E. (Clin Cardiol 2001)
    232. STAT5 pathway: target of anti-CD4 antibody in attenuation of IL-2 receptor signaling. (PubMed id 11330544)9 Goebel J....Lowry R.P. (Transplantation 2001)
    233. Soluble TNF-alpha receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight. (PubMed id 11150007)9 Shearer W.T....Dinges D.F. (J. Allergy Clin. Immunol. 2001)
    234. Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the beta-chain of the interleukin-2 receptor. (PubMed id 10712671)9 Searle R.F....Lang A.K. (Immunology 2000)
    235. Interleukin-4 enhances the in vitro precursor cell recruitment for tumor-specific T lymphocytes in patients with glioblastoma. (PubMed id 10687133)9 Faber C....Heuschling P. (J. Immunother. 2000)
    236. Tumor-induced dysfunction in interleukin-2 production and interleukin-2 receptor signaling: a mechanism of immune escape. (PubMed id 10685665)9 Rayman P....Finke J.H. (Cancer J Sci Am 2000)
    237. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids. (PubMed id 10920190)9 Bianchi M....Ivashkiv L.B. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    238. Soluble TNF and IL-2 receptors in patients with breast cancer. (PubMed id 11208388)9 TesarovA! P....Tesar V. (Med. Sci. Monit. 2000)
    239. Effects of zinc deficiency on Th1 and Th2 cytokine shifts. (PubMed id 10944485)9 Prasad A.S. (J. Infect. Dis. 2000)
    240. T-lymphocyte subpopulations do not express identical combinations of interleukin-2 receptor chains in the early phase of their activation and proliferation. (PubMed id 10931379)9 Perola O....Pelkonen J. (Scand. J. Immunol. 2000)
    241. B7 expression and antigen presentation by human brain endothelial cells: requirement for proinflammatory cytokines. (PubMed id 10749102)9 Prat A....Antel J.P. (J. Neuropathol. Exp. Neurol. 2000)
    242. Increased expression of interleukin-4 during liver allograft rejection. (PubMed id 10365823)9 Conti F....Zafrani E.S. (J. Hepatol. 1999)
    243. Efficient gene delivery to quiescent interleukin-2 (IL-2)-dependent cells by murine leukemia virus-derived vectors harboring IL-2 chimeric envelope glycoproteins. (PubMed id 10397706)9 Maurice M....Cosset F.L. (Blood 1999)
    244. Phenotypic analysis and proliferative responses of human endometrial granulated lymphocytes during the menstrual cycle. (PubMed id 10084960)9 Searle R.F....Bulmer J.N. (Biol. Reprod. 1999)
    245. Diminished interferon-gamma production in gastric mucosa T lymphocytes after H. pylori eradication in duodenal ulcer patients. (PubMed id 10430335)9 Ihan A....Kopitar A. (Hepatogastroenterology 1999)
    246. Immunomodulating therapy with rIL-2 and interferon alpha-induces in vivo expression of Bcl-2, Fas (APO-1/CD95), and Fas ligand on peripheral lymphocytes (a pilot study). (PubMed id 10629645)9 Demir G....Berkarda B. (Anticancer Res. 1999)
    247. Inhibitory effects of the Trypanosoma cruzi membrane glycoprotein AGC10 on the expression of IL-2 receptor chains and secretion of cytokines by subpopulations of activated human T lymphocytes. (PubMed id 10359123)9 Kierszenbaum F....Sztein M.B. (Eur. J. Immunol. 1999)
    248. Livedo vasculopathy vs small vessel cutaneous vasculitis: cytokine and platelet P-selectin studies. (PubMed id 9554296)9 Papi M....Cavalieri R. (Arch Dermatol 1998)
    249. [Soluble TNF and IL-2 receptors in patients with breast carcinoma]. (PubMed id 9727208)9 TesarovA! P....Tesar V. (Cas. Lek. Cesk. 1998)
    250. Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma. (PubMed id 9060545)9 Du Bois J.S....Atkins M.B. (J. Clin. Oncol. 1997)
    251. Alteration of interleukin-2 (IL-2) and soluble IL-2 receptor secretion in the sera and urine of patients with rickettsial boutonneuse fever. (PubMed id 8985208)9 Mansueto S....Cillari E. (J. Infect. Dis. 1997)
    252. Genes for interleukin-2 receptor beta chain, interleukin-1 beta, and schizophrenia: no evidence for the association or linkage. (PubMed id 9184320)9 Tatsumi M....Nanko S. (Am. J. Med. Genet. 1997)
    253. Medroxyprogesterone acetate reduces the in vitro production of cytokines and serotonin involved in anorexia/cachexia and emesis by peripheral blood mononuclear cells of cancer patients. (PubMed id 9274442)9 Mantovani G....Del Giacco G.S. (Eur. J. Cancer 1997)
    254. Soluble interleukin-2 receptor serum level as a predictor of locoregional control and survival for patients with head and neck carcinoma: results of a multivariate prospective study. (PubMed id 9083163)9 Tartour E....Rodriguez J. (Cancer 1997)
    255. Optimal nerve growth factor trophic signals mediated by synergy of TrkA and p75 receptor-specific ligands. (PubMed id 9236214)9 Maliartchouk S. and Saragovi H.U. (J. Neurosci. 1997)
    256. Immunohistochemical analysis of the neurotrophins BDNF and NT-3 and their receptors trk B, trk C, and p75 in the developing chick retina. (PubMed id 9364722)9 Das I....Sparrow J.R. (Vis. Neurosci. 1997)
    257. Influence of some immune factors on the IL-6 and soluble IL-2 receptors in haemodialysed patients. (PubMed id 9285313)9 KozioA8-Montewka M....Przylepa E. (Int Urol Nephrol 1997)
    258. IL2 fused to lectin-deficient ricin is toxic to human leukemia cells expressing the IL2 receptor. (PubMed id 9001414)9 Frankel A.E....Tagge E.P. (Leukemia 1997)
    259. Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain. (PubMed id 9129156)9 Adachi M....Imai K. (Oncogene 1997)
    260. Phenotypic and functional characterization of peripheral blood and bone marrow natural killer cells prior to autologous transplantation. (PubMed id 8704680)9 Arbour S....Roy D.C. (Bone Marrow Transplant. 1996)
    261. A randomised dose escalation study of subcutaneous interleukin 2 with and without levamisole in patients with metastatic renal cell carcinoma or malignant melanoma. (PubMed id 8855983)9 Ahmed F.Y....Gore M.E. (Br. J. Cancer 1996)
    262. Effect of rapamycin on the expression of the IL-2 receptor (CD25). (PubMed id 8565319)9 Woerly G....Ryffel B. (Clin. Exp. Immunol. 1996)
    263. CTLA-4 ligation blocks CD28-dependent T cell activation. (PubMed id 8676075)9 Walunas T.L....Bluestone J.A. (J. Exp. Med. 1996)
    264. Flow cytometric characterisation of the &quot;false naive&quot; (CD45RA+, CD45RO-, CD29 bright+) peripheral blood T-lymphocytes in health and in rheumatoid arthritis. (PubMed id 8853229)9 Neidhart M....BrA1hlmann P. (Rheumatol. Int. 1996)
    265. Il-2 receptor expression on gastric mucosa T lymphocytes is enhanced in duodenal ulcer patients compared with non-ulcer dyspeptic patients. (PubMed id 8975986)9 Ihan A....Gubina M. (Hepatogastroenterology 1996)
    266. The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. (PubMed id 8717512)9 Sugamura K....Takeshita T. (Annu. Rev. Immunol. 1996)
    267. Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain. (PubMed id 8580378)9 Kirken R.A....Farrar W.L. (Cytokine 1995)
    268. IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor. (PubMed id 7612266)9 Minami Y. and Taniguchi T. (Curr. Opin. Cell Biol. 1995)
    269. Circulating soluble interleukin-2 receptor alpha and beta chain in inflammatory bowel disease. (PubMed id 7639234)9 Nielsen O.H....Kirman I. (Am. J. Gastroenterol. 1995)
    270. Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor beta chain (IL-2R beta). (PubMed id 8544854)9 Moreau J.L....ThA"ze J. (Mol. Immunol. 1995)
    271. Interleukin 6 (IL-6) and soluble IL-2 receptor levels in patients with rheumatoid arthritis treated with low dose oral methotrexate. (PubMed id 7738942)9 Crilly A....Madhok R. (J. Rheumatol. 1995)
    272. Serum neopterin and soluble interleukin-2 receptor for prediction of a shock state in gram-negative sepsis. (PubMed id 7647844)9 Delogu G....Signore L. (J Crit Care 1995)
    273. Immunoregulatory effects of a synthetic monosaccharide. (PubMed id 8576539)9 Chang D.M. (Immunopharmacol Immunotoxicol 1995)
    274. Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro. (PubMed id 8675621)9 Carson W.E....Caligiuri M.A. (J. Clin. Invest. 1995)
    275. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. (PubMed id 7665592)9 Goldsmith M.A....Greene W.C. (J. Biol. Chem. 1995)
    276. Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain. (PubMed id 7868880)9 Goldsmith M.A....Greene W.C. (J. Immunol. 1995)
    277. [Effect of epimedium sagittatum on soluble IL-2 receptor and IL-6 levels in patients undergoing hemodialysis]. (PubMed id 7796653)9 Chen X....Wang J. (Zhonghua Nei Ke Za Zhi 1995)
    278. HIV type 1 protease activation of NF-kappa B within T lymphoid cells. (PubMed id 7742037)9 Zhang D....Byrn R.A. (AIDS Res. Hum. Retroviruses 1995)
    279. Changes in interleukin-1 beta and soluble interleukin-2 receptor levels in CSF and serum of schizophrenic patients. (PubMed id 8562579)9 Barak V....Roisman I. (J Basic Clin Physiol Pharmacol 1995)
    280. Interleukin-2 binding proteins in sera from normal subjects and multiple sclerosis patients. (PubMed id 7501143)9 Trotter J.L....Cross A.H. (Neurology 1995)
    281. Non random activation of endogenous interleukin-2, (IL-2), IL-2 receptor alpha and IL-2 receptor beta genes after transfection of mouse fibroblasts with a cDNA for the alpha chain of the human IL-2 receptor. (PubMed id 7621867)9 Han D....Azzarone B. (Eur. J. Immunol. 1995)
    282. Modulation of the cytokine and acute-phase response to major surgery by recombinant interleukin-2. (PubMed id 7881967)9 Deehan D.J....Eremin O. (Br J Surg 1995)
    283. Imbalance of the interleukin 2 system in children with IDDM. (PubMed id 8056185)9 Tomoda T....Taniguchi T. (Diabetologia 1994)
    284. High cerebrospinal fluid and serum levels of tumor necrosis factor-alpha in asymptomatic HIV-1 seropositive individuals. Correlation with interleukin-2 and soluble IL-2 receptor. (PubMed id 7807163)9 Ciardi M....Cirelli A. (J. Neurol. Sci. 1994)
    285. Effects of radiolabelled murine antibody infusion on TNF-alpha, IL-1 beta, and soluble IL-2 receptor in cancer patients. (PubMed id 7931817)9 Gridley D.S....Slater J.M. (J. Clin. Lab. Anal. 1994)
    286. Serum levels of interleukin 1-beta, tumor necrosis factor-alpha, soluble interleukin 2 receptor and soluble CD8 in seronegative spondylarthropathies. (PubMed id 8202660)9 Toussirot E....Acquaviva P.C. (Rheumatol. Int. 1994)
    287. Chimeric fusion protein toxin DAB486IL-2 in advanced mycosis fungoides and the Sezary syndrome: correlation of activity and interleukin-2 receptor expression in a phase II study. (PubMed id 8080984)9 Foss F.M....Woodworth T. (Blood 1994)
    288. Growth regulation of a T-cell lymphoma via the T-cell receptor. (PubMed id 8289463)9 O'Neill H.C. (Leuk. Res. 1994)
    289. Functional role of IL-2 receptors on tumour-infiltrating lymphocytes. (PubMed id 8198969)9 Trentin L....Semenzato G. (Br. J. Cancer 1994)
    290. Chemoattractant activity of IL-2 for human lymphocytes: a requirement for the IL-2 receptor beta-chain. (PubMed id 8045589)9 Wilkinson P.C. and Newman I. (Immunology 1994)
    291. Immunomodulation in patients receiving intravenous Bryostatin 1 in a phase I clinical study: comparison with effects of Bryostatin 1 on lymphocyte function in vitro. (PubMed id 7954524)9 Scheid C....Stern P.L. (Cancer Immunol. Immunother. 1994)
    292. Localization of T lymphocytes and macrophages expressing IL-1, IL-2 receptor, IL-6 and TNF in human aortic intima. Role of cell-mediated immunity in human atherogenesis. (PubMed id 8291216)9 Kishikawa H....Watanabe T. (Virchows Arch A Pathol Anat Histopathol 1993)
    293. Evidence for an ongoing role of class I histocompatibility molecules for the production of interleukin-2 in response to suboptimal concentrations of phytohaemagglutinin. (PubMed id 8484101)9 Hashimoto S....Michalski J.P. (Scand. J. Immunol. 1993)
    294. Human T-cell leukemia virus type I-induced proliferation of human immature CD2+CD3- thymocytes. (PubMed id 8102412)9 Maguer V....Dodon M.D. (J. Virol. 1993)
    295. [Characterization of autologous-tumor specific cytotoxic T cells induced by means of butanol-extracted soluble antigen from T lymphocytes in colon cancer patients]. (PubMed id 8464410)9 Hamagashira K. (Nihon Geka Gakkai Zasshi 1993)
    296. Interleukin-2 increases production and secretion of parathyroid hormone-related peptide by human T cell leukemia virus type I-infected T cells: possible role in hypercalcemia associated with adult T cell leukemia. (PubMed id 8099324)9 Ikeda K....Matsumoto T. (Endocrinology 1993)
    297. Membrane-bound and soluble IL-2 receptors (p55 and p75 chains) on peripheral blood mononuclear cells from patients with solid malignancies. (PubMed id 7889544)9 Mantovani G....Pusceddu G. (Cell Biophys. 1993)
    298. Affinity purification and characterization of anti-Tac(Fv)-C3-PE38KDEL: A highly potent cytotoxic agent specific to cells bearing IL-2 receptors. (PubMed id 8431514)9 Spence C....Bailon P. (Bioconjug. Chem. 1993)
    299. Upregulation by retinoic acid of interleukin-2-receptor mRNA in human T lymphocytes. (PubMed id 7678784)9 Sidell N....Bhatti L. (Cell. Immunol. 1993)
    300. Immune stimulatory and anti-tumour properties of haemin. (PubMed id 8370158)9 Tsuji A....Novogrodsky A. (Clin. Exp. Immunol. 1993)
    301. Soluble receptors for tumor necrosis factor: occurrence in association with normal delivery at term. (PubMed id 8395036)9 Austgulen R....Espevik T. (Obstet Gynecol 1993)
    302. Legionella pneumophila protease inactivates interleukin-2 and cleaves CD4 on human T cells. (PubMed id 8335371)9 Mintz C.S....Malek T. (Infect. Immun. 1993)
    303. Intrathecal synthesis of interleukin-2 and soluble IL-2 receptor in asymptomatic HIV-1 seropositive individuals. Correlation with local production of specific IgM and IgG antibodies. (PubMed id 8468587)9 Ciardi M....Cirelli A. (J. Neurol. Sci. 1993)
    304. [Cytokine levels in patients with thrombotic thrombocytopenic purpura]. (PubMed id 7679449)9 Wada H....Shirakawa S. (Nippon Rinsho 1993)
    305. [Interleukin 2 (IL-2) and its receptor (IL-2R) in healthy individuals and with various disease states]. (PubMed id 8303976)9 Mazur G. and Frydecka I. (Acta Haematol Pol 1993)
    306. Pregnancy-associated, lymphocyte-derived suppressor factor inhibits protein kinase C activity. (PubMed id 8229996)9 Blumenthal E.J....Hoversland R.C. (J. Reprod. Immunol. 1993)
    307. Analysis of high and low responses to Staphylococcus aureus and interleukin 2 in human B lymphocytes. (PubMed id 8288726)9 Peckham D.W....Ashman R.F. (J. Clin. Immunol. 1993)
    308. In vivo relationship of interleukin-2 and soluble IL-2 receptor to blood-brain barrier impairment in patients with active multiple sclerosis. (PubMed id 8423463)9 Sharief M.K....Thompson E.J. (J. Neurol. 1993)
    309. Selection of internalization-deficient cells by interleukin-2-Pseudomonas exotoxin chimeric protein: the cytoplasmic domain of the interleukin-2 receptor beta chain does not contribute to internalization of interleukin-2. (PubMed id 8258333)9 Furse R.K. and Malek T.R. (Eur. J. Immunol. 1993)
    310. Does interleukin-2 restore lymphocyte responses suppressed by Trypanosoma cruzi? (PubMed id 8288318)9 Kierszenbaum F....Sztein M.B. (Immunology 1993)
    311. Impaired T cell functions during amphibian metamorphosis: IL-2 receptor expression and endogenous ligand production. (PubMed id 1498041)9 Ruben L.N....Balls M. (Mech. Dev. 1992)
    312. Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor. (PubMed id 1420599)9 Lagoo-Deenadayalan S....Grimm E.A. (Lymphokine Cytokine Res. 1992)
    313. Expression of a functional p75 interleukin-2 receptor on lung lymphocytes from patients with human immunodeficiency virus type 1 (HIV-1) infection. (PubMed id 1430108)9 Zambello R....Semenzato G. (J. Clin. Immunol. 1992)
    314. Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression. (PubMed id 1453505)9 Li H....Luo Y. (J. Tongji Med. Univ. 1992)
    315. Structure and function of IL-2 and IL-2 receptors. (PubMed id 1524574)9 Taniguchi T. (Behring Inst. Mitt. 1992)
    316. Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R. (PubMed id 1500859)9 Voss S.D....Robb R.J. (J. Exp. Med. 1992)
    317. c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain. (PubMed id 1549560)9 Hatakeyama M....Taniguchi T. (Proc. Natl. Acad. Sci. U.S.A. 1992)
    318. Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor beta subunit, the essential region for growth stimulation and Lck-binding domain. (PubMed id 1460037)9 Satoh T....Kaziro Y. (J. Biol. Chem. 1992)
    319. Human T lymphotropic virus type-I (HTLV-I) immortalizes human T cells in vitro--its implication in the pathogenesis of adult T cell leukemia (ATL). (PubMed id 1419953)9 Maeda M. (Hum. Cell 1992)
    320. The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta chains (p55 and p75). (PubMed id 1565844)9 Scheibenbogen C....Hunstein W. (Res. Immunol. 1992)
    321. CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes. (PubMed id 1355105)9 MittrA1cker H.W....Fleischer B. (J. Exp. Med. 1992)
    322. Plasma cytokine levels in thrombotic thrombocytopenic purpura. (PubMed id 1609769)9 Wada H....Shirakawa S. (Am. J. Hematol. 1992)
    323. Decreased interleukin-2 receptor beta chain expression by peripheral blood lymphocytes in chronic liver disease. (PubMed id 1325198)9 Masumoto T....Ohta Y. (J. Gastroenterol. Hepatol. 1992)
    324. Increased levels of inflammatory cytokines in human skin lymph derived from sodium lauryl sulphate-induced contact dermatitis. (PubMed id 1390170)9 Hunziker T....Braathen L.R. (Br. J. Dermatol. 1992)
    325. [A study about the ability of interleukin-2 production, interleukin-2 receptor expression by lymphocytes from patients with lung cancer]. (PubMed id 1339618)9 Liu S.B. (Zhonghua Jie He He Hu Xi Za Zhi 1992)
    326. Different lymphoid cell populations produce varied levels of neopterin, beta 2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, interferon-gamma or tumour necrosis factor-alpha. (PubMed id 1606739)9 Hofmann B....Fahey J.L. (Clin. Exp. Immunol. 1992)
    327. [Pathogenesis of T-lymphocyte alveolitis associated with HTLV-I infection]. (PubMed id 1630041)9 Sugimoto M. (Nihon Kyobu Shikkan Gakkai Zasshi 1992)
    328. Adenosine deaminase activity and free IL-2 receptor levels in serum from patients with mycoplasma pneumonia. (PubMed id 1907690)9 Suga M....Araki S. (Jpn. J. Med. 1991)
    329. Serum levels of soluble IL-2 receptor, IL-4 and IgE-binding factors in childhood allergic diseases. (PubMed id 1864009)9 Matsumoto T....Yodoi J. (Clin. Exp. Immunol. 1991)
    330. Soluble CD8, IL-2 receptor, and tumor necrosis factor-alpha levels in steroid-resistant acute graft-versus-host disease. Relation with subsequent response to anti-IL-2 receptor monoclonal antibody treatment. (PubMed id 1910217)9 Tiberghien P....Herve P. (Transplantation 1991)
    331. [Interactions and biological mechanisms of action of molecular signal peptides. II. Interleukin 2 (IL-2)]. (PubMed id 1836210)9 Wustrow T.P. (HNO 1991)
    332. Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase. (PubMed id 1713578)9 Remillard B....Varticovski L. (J. Biol. Chem. 1991)
    333. The role of glutathione in lymphocyte activation--II. Effects of buthionine sulfoximine and 2-cyclohexene-1-one on early and late activation events. (PubMed id 1709148)9 Hamilos D.L....Wedner H.J. (Int. J. Immunopharmacol. 1991)
    334. Expression of MHC class I and II antigens and the Il-2 receptor in rejection, myocarditis and dilated cardiomyopathy. (PubMed id 1915444)9 Hufnagel G. and Maisch B. (Eur. Heart J. 1991)
    335. The immunosuppressive properties of enisoprost and a 5-lipoxygenase inhibitor (SC-45662). (PubMed id 1750068)9 Weir M.R....Moran M.A. (Transplantation 1991)
    336. The immunosuppressive agent FK506 inhibits in vitro expression of membrane-bound and soluble interleukin-2 receptors on resting but not on activated human lymphocytes. (PubMed id 1720417)9 Karlsson H....NAossberger L. (Immunol. Lett. 1991)
    337. Influence of growth hormone-releasing hormone (GHRH) on phytohemagglutinin-induced lymphocyte activation: comparison of two synthetic forms. GHRH and PHA-induced lymphocyte activation. (PubMed id 1833862)9 Valtorta A....Severi F. (Thymus 1991)
    338. Negative regulation of interleukin-2 production in primary lymphocytes by 12-O-tetradecanoylphorbol-13-acetate. (PubMed id 1715761)9 Mastro A.M....Pishak S.A. (Lymphokine Cytokine Res. 1991)
    339. Expression on cells of early human pregnancy decidua, of the p75, IL-2 and p145, IL-4 receptor proteins. (PubMed id 2045128)9 Starkey P.M. (Immunology 1991)
    340. Induction of interleukin 2 (IL 2) and interferon-gamma and enhancement of IL 2 receptor expression by a CD26 monoclonal antibody. (PubMed id 1673434)9 Plana M....Vives J. (Eur. J. Immunol. 1991)
    341. Hemodialysis with cuprophane membrane modulates interleukin-2 receptor expression. (PubMed id 2067197)9 Zaoui P....Hakim R.M. (Kidney Int. 1991)
    342. Effects of hyperlipaemic serum on interleukin-2 (IL-2) production, IL-2 receptor expression, and T cell proliferation induced by IL-2 in cynomolgus monkeys. (PubMed id 1875552)9 Terao K. and Fukase Y. (amp 1991)
    343. Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. (PubMed id 1768652)9 Molitor J.A....Greene W.C. (New Biol. 1991)
    344. Different mechanisms of activation of proliferating CD3+ cells in patients with lymphoproliferative disease of granular lymphocytes. (PubMed id 1835747)9 Zambello R....Pizzolo G. (Leukemia 1991)
    345. Regulation of the interleukin 2 receptor complex tyrosine kinase activity in vitro. (PubMed id 1751780)9 Michiel D.F....Farrar W.L. (Cytokine 1991)
    346. Serum interleukin-2 (IL-2), soluble IL-2 receptors and tumor necrosis factor-alfa levels are significantly increased in acute myeloid leukemia patients. (PubMed id 1999955)9 Cimino G....Mandelli F. (Leukemia 1991)
    347. Soluble IL-2 receptor and CD25 cells in psoriasis: effects of cyclosporin A and PUVA therapy. (PubMed id 1864010)9 Duncan J.I....Thomson A.W. (Clin. Exp. Immunol. 1991)
    348. Fibronectin augments anti-CD3-mediated IL-2 receptor (CD25) expression on human peripheral blood lymphocytes. (PubMed id 1826861)9 Cardarelli P.M....Morgan E.L. (Cell. Immunol. 1991)
    349. Biochemical evidence for a third chain of the interleukin-2 receptor. (PubMed id 1939240)9 Saito Y....Honjo T. (J. Biol. Chem. 1991)
    350. Establishment of an IL-2 independent, human T-cell line possessing only the p70 IL-2 receptor. (PubMed id 1879969)9 Starkebaum G....Ruscetti F.W. (Int. J. Cancer 1991)
    351. Elevation of cyclic adenosine monophosphate levels independently down regulates IL-1, IL-2, and IL-2 receptor (CD25) syntheses. (PubMed id 2177038)9 Iwaz J....Revillard J.P. (Int. J. Immunopharmacol. 1990)
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    490. 99mTc-interleukin-2 scintigraphy as a potential tool for evaluating tumor-infiltrating lymphocytes in melanoma lesions: a validation study. (PubMed id 15471828)9 Signore A....Calvieri S. (J. Nucl. Med. 2004)
    491. Serological immunomarkers in cutaneous T cell lymphoma. (PubMed id 15539892)9 Hassel J.C....Dummer R. (Dermatology (Basel) 2004)
    492. Enhanced tumorigenesis in HTLV-1 tax-transgenic mice deficient in interferon-gamma. (PubMed id 15292059)9 Mitra-Kaushik S....Ratner L. (Blood 2004)
    493. Risk factors relating blood markers of inflammation and nutritional status to survival in cachectic geriatric patients in a randomized clinical trial. (PubMed id 15450049)9 Yeh S.S....Schuster M.W. (J Am Geriatr Soc 2004)
    494. [Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor]. (PubMed id 16108608)9 Osawa M....Akagawa K. (Jpn J Antibiot 2004)
    495. Evolution of immunosuppression in liver transplantation: contribution of cyclosporine. (PubMed id 15041353)9 Furukawa H. and Todo S. (Transplant. Proc. 2004)
    496. Effects of lornoxicam on the physiology of severe sepsis. (PubMed id 15566594)9 MemiA9 D....PamukAsu Z. (Crit Care 2004)
    497. Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain. (PubMed id 15123770)9 RatthAc C. and Girard D. (J. Leukoc. Biol. 2004)
    498. The carbohydrate recognition by cytokines modulates their physiological activities. (PubMed id 15467395)9 Yamashita K. and Fukushima K. (Glycoconj. J. 2004)
    499. Cyclosporin is safe and effective in severe atopic dermatitis of childhood. Report of three cases. (PubMed id 15249910)9 Leonardi S....La Rosa M. (Minerva Pediatr. 2004)
    500. Monitoring of T-cell subsets in patients treated with anti-CD 25 antibody. (PubMed id 15041394)9 Praditpornsilpa K....Tungsanga K. (Transplant. Proc. 2004)
    501. Immunosuppression use in renal transplantation from Asian transplant centers: a preliminary report from the Asian Transplant Registry. (PubMed id 15518679)9 Vathsala A. (Transplant. Proc. 2004)
    502. [Host immunity in colorectal cancer patients treated with low-dose Leucovorin plus 5-fluorouracil]. (PubMed id 15553714)9 Kobayashi R....Ogawa K. (amp 2004)
    503. Transplant immunology. (PubMed id 14523805)9 Aw M.M. (J. Pediatr. Surg. 2003)
    504. Identification and functional characterization of voltage-dependent calcium channels in T lymphocytes. (PubMed id 12954628)9 Kotturi M.F....Jefferies W.A. (J. Biol. Chem. 2003)
    505. Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. (PubMed id 14581351)9 Kuniyasu H....Fidler I.J. (Clin. Cancer Res. 2003)
    506. Induction of cytokines and adhesion molecules in stable hemodialysis patients: is there an effect of membrane material? (PubMed id 14583663)9 Hoffmann U....KrAomer B.K. (Am. J. Nephrol. 2003)
    507. T cell anergy. (PubMed id 12471050)9 Schwartz R.H. (Annu. Rev. Immunol. 2003)
    508. Differential gene expression of cytokine and cell surface molecules in T cell subpopulation derived from mammary gland secretion of cows. (PubMed id 14750552)9 Asai K....Kumagai K. (Am. J. Reprod. Immunol. 2003)
    509. Investigation of the immunostimulatory properties of oxihumate. (PubMed id 12710739)9 JoonAc G.K....van Rensburg C.E. (Z. Naturforsch., C, J. Biosci. 2003)
    510. Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1. (PubMed id 12915736)9 Heredia A....Redfield R.R. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    511. Long-term proliferation and survival of in vitro-activated T cells is dependent on Interleukin-2 receptor signalling but not on the high-affinity IL-2R. (PubMed id 14629624)9 Hedfors I.A. and Brinchmann J.E. (Scand. J. Immunol. 2003)
    512. Immune system alterations in lung cancer patients. (PubMed id 12797908)9 Mazzoccoli G....Perfetto F. (Int J Immunopathol Pharmacol 2003)
    513. Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study). (PubMed id 12943870)9 Cesari M....Pahor M. (Am. J. Cardiol. 2003)
    514. Interleukin-2 receptor-directed therapies for cutaneous lymphomas. (PubMed id 14710895)9 Foss F.M. and Waldmann T.A. (Hematol. Oncol. Clin. North Am. 2003)
    515. Cytokine production patterns and antibody response to measles vaccine. (PubMed id 12922130)9 Ovsyannikova I.G....Poland G.A. (Vaccine 2003)
    516. Impaired production of cytokines is an independent predictor of mortality in HIV-1-infected patients. (PubMed id 12598772)9 Ostrowski S.R....Ullum H. (AIDS 2003)
    517. Lymphocyte counts independently predict overall survival in advanced cancer patients: a biomarker for IL-2 immunotherapy. (PubMed id 12973028)9 Fumagalli L.A....Nespoli A. (J. Immunother. 2003)
    518. New developments in allotransplant immunology. (PubMed id 14633790)9 Barrett A.J....Chao N. (Hematology Am Soc Hematol Educ Program 2003)
    519. Drug-induced hyperergic vasculitis--activity of selected cytokines and acute phase proteins in plasma. (PubMed id 15314957)9 Chodorowska G. and Czelej D. (Ann Univ Mariae Curie Sklodowska Med 2003)
    520. Pretreatment with interleukin-2 modulates perioperative immunodysfunction in patients with renal cell carcinoma. (PubMed id 12779014)9 BAPhm M....Allhoff E.P. (Folia Biol. (Praha) 2003)
    521. Interleukin-6, soluble interleukin-2 receptor and soluble interleukin-6 receptor in the sera of patients with different histological patterns of rheumatoid synovitis. (PubMed id 12673891)9 Klimiuk P.A....Chwiecko J. (Clin. Exp. Rheumatol. 2003)
    522. Activation of human intraepithelial lymphocytes reduces CD3 expression. (PubMed id 12780688)9 Ebert E.C. (Clin. Exp. Immunol. 2003)
    523. TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients. (PubMed id 12608932)9 Wakelkamp I.M....Prummel M.F. (Clin. Endocrinol. (Oxf) 2003)
    524. Impact of acute vivax malaria on the immune system and viral load of HIV-positive subjects. (PubMed id 14687465)9 Chen X....Zhang Z. (Chin. Med. J. 2003)
    525. Serum levels of interleukin-10, interleukin-12 and soluble interleukin-2 receptor in chronic liver disease type C. (PubMed id 14571788)9 Kitaoka S....Kawasaki H. (Hepatogastroenterology 2003)
    526. Serum cytokine profiles in patients with adult onset Still's disease. (PubMed id 14677188)9 Choi J.H....Park H.S. (J. Rheumatol. 2003)
    527. Effect of pericardial fluid pro-inflammatory cytokines on hemodynamic parameters. (PubMed id 12901854)9 Ege T....Duran E. (Cytokine 2003)
    528. [Kidney transplantation in Germany - 2002]. (PubMed id 14628230)9 Lutz J....Heemann U. (Zentralbl Chir 2003)
    529. Drug-induced urticaria--activity of selected cytokines and acute phase proteins in plasma. (PubMed id 15314956)9 Czelej D....Lechowska-Mazur I. (Ann Univ Mariae Curie Sklodowska Med 2003)
    530. IL-2 receptor blockers in liver transplantation: initial experience with daclizumab in Chile. (PubMed id 14612001)9 Innocenti F....Rius M. (Transplant. Proc. 2003)
    531. Systemic immune cell activation in a subgroup of patients with idiopathic pulmonary fibrosis. (PubMed id 12915745)9 Homolka J....MA1ller-Quernheim J. ( international review of thoracic diseases 2003)
    532. Pneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniae. (PubMed id 12654830)9 Rogers P.D....McDaniel L.S. (Infect. Immun. 2003)
    533. A case of intravascular large B-cell lymphoma with multiple organ involvement. (PubMed id 14739519)9 Yanagihori H....Kaneko F. (J. Dermatol. 2003)
    534. A review of the cytokine network in multiple myeloma: diagnostic, prognostic, and therapeutic implications. (PubMed id 12733143)9 Lauta V.M. (Cancer 2003)
    535. Cholesterol and interleukin-6 concentrations relate to outcomes in burn-injured patients. (PubMed id 12792232)9 Vanni H.E....Parker T.S. (amp 2003)
    536. [Influence of erythromycin and the metabolite, EM201 on IL-2 receptor signaling]. (PubMed id 14679762)9 Osawa T....Akagawa K. (Jpn J Antibiot 2003)
    537. Induction of interleukin-2 receptor alpha (IL-2Ralpha) expression by interleukin-2: important role of the interleukin-2 receptor beta chain region between the two Stat5 docking sites. (PubMed id 12231477)9 Imbert V....Nabholz M. (Eur. Cytokine Netw. 2002)
    538. Systemic immune parameters and sleep after ultra-low dose administration of IL-2 in healthy men. (PubMed id 12480497)9 Lange T....Born J. (Brain Behav. Immun. 2002)
    539. Concentrations of cytokines, soluble interleukin-2 receptor, and soluble CD30 in sera of patients with hepatitis B virus infection during acute and convalescent phases. (PubMed id 12414777)9 Monsalve-De Castillo F....Callejas D. (Clin. Diagn. Lab. Immunol. 2002)
    540. Activation of the inflammatory response system in autism. (PubMed id 11803234)9 Croonenberghs J....Maes M. (Neuropsychobiology 2002)
    541. Alterations in immunocyte tumor necrosis factor receptor and apoptosis in patients with congestive heart failure. (PubMed id 12170032)9 Rumalla V.K....Lowry S.F. (Ann. Surg. 2002)
    542. Streptokinase promotes development of dipeptidyl peptidase IV (CD26) autoantibodies after fibrinolytic therapy in myocardial infarction patients. (PubMed id 12414758)9 Cuchacovich M....Gonzalez-Gronow M. (Clin. Diagn. Lab. Immunol. 2002)
    543. Immunosuppressive and anticancer effect of a mammalian ribonuclease that targets high-affinity interleukin-2-receptors. (PubMed id 12022372)9 Yamamura T....Kitajima M. (Eur J Surg 2002)
    544. IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production. (PubMed id 12193748)9 McDyer J.F....Ragheb J.A. (J. Immunol. 2002)
    545. Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. (PubMed id 11964300)9 Gray C.P....Hersey P. (Blood 2002)
    546. Novel pharmacotherapeutic approaches to prevention and treatment of GVHD. (PubMed id 11929336)9 Jacobsohn D.A. and Vogelsang G.B. (Drugs 2002)
    547. Hypereosinophilia as a presenting sign of acute graft-versus-host disease after allogeneic bone marrow transplantation. (PubMed id 12499902)9 McNeel D....Buzyn A. (Transplantation 2002)
    548. [An elderly non-Hodgkin lymphoma patient with a massive tumor of the heart]. (PubMed id 12229122)9 Hasegawa Y....Yoshida K. (Rinsho Ketsueki 2002)
    549. Interleukin-15 interactions with interleukin-15 receptor complexes: characterization and species specificity. (PubMed id 12453470)9 Eisenman J....Park L.S. (Cytokine 2002)
    550. Tumor necrosis factor alpha, interleukin 2, and soluble interleukin 2 receptor levels in human immunodeficiency virus type 1-infected individuals receiving intermittent cycles of interleukin 2. (PubMed id 12015902)9 Fortis C....Poli G. (AIDS Res. Hum. Retroviruses 2002)
    551. Comparison of serum NO, TNF-alpha, IL-1beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus. (PubMed id 11988817)9 Doganay S....Savli H. (Eye (Lond) 2002)
    552. Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer. (PubMed id 11915173)9 Berghella A.M....Adorno D. (amp 2002)
    553. Analysis of host response to hepatectomy by simultaneous measurement of cytokines in the portal vein, caval vein and radial artery. (PubMed id 12449519)9 Kanaoka Y....Tanaka N. (J. Int. Med. Res. 2002)
    554. Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells. (PubMed id 12200381)9 Sereti I....Lane H.C. (Blood 2002)
    555. Association between injury pattern of patients with multiple injuries and circulating levels of soluble tumor necrosis factor receptors, interleukin-6 and interleukin-10, and polymorphonuclear neutrophil elastase. (PubMed id 11988666)9 Hensler T....Neugebauer E.A. (J Trauma 2002)
    556. Role of interleukin-18 and T-helper type 1 cytokines in the development of Mycoplasma pneumoniae pneumonia in adults. (PubMed id 12006434)9 Tanaka H....Abe S. (Chest 2002)
    557. [Cytokines and soluble cytokine receptors in the perioperative period]. (PubMed id 12688152)9 Maruna P....PeskovA! M. (Sb Lek 2002)
    558. Interleukin-2 inhibits proliferation of HPV-associated tumor cells and halts tumor growth in vivo. (PubMed id 12470652)9 Casana P.H....Arana M.J. (Biochem. Biophys. Res. Commun. 2002)
    559. Novel therapeutics for the treatment of graft-versus-host disease. (PubMed id 12225248)9 Jacobsohn D.A. (Expert Opin Investig Drugs 2002)
    560. KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line. (PubMed id 12635495)9 Sugimoto M....Nakaike S. (Drugs Exp Clin Res 2002)
    561. An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines. (PubMed id 12271139)9 Hwang E.S....Ho I.C. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    562. Experimental autoimmune encephalomyelitis in the Wistar rat: dependence of MBP-specific T cell responsiveness on B7 costimulation. (PubMed id 12389644)9 Zhou J....Mamula M.J. (Autoimmunity 2002)
    563. Early clinical experience with a novel rapamycin derivative. (PubMed id 11805723)9 Nashan B. (Ther Drug Monit 2002)
    564. [Th1-cytokines in chronic hepatitis B and C]. (PubMed id 12173430)9 PriA-miagi L.S....Lisitsyna S.A. (Vopr. Virusol. 2002)
    565. EBV associated hemophagocytic syndrome accompanied by central pontine myelinolysis. (PubMed id 12481907)9 Uehara E....Ishida T. (amp 2002)
    566. A prospective study of inflammation markers in patients at risk of indirect acute lung injury. (PubMed id 11954822)9 Takala A....Repo H. (Shock 2002)
    567. Interleukin-2 as a therapeutic agent. (PubMed id 11837757)9 Sule N.S....Kamath S. (J Assoc Physicians India 2001)
    568. Simvastatin treatment is associated with improvement in coronary endothelial function and decreased cytokine activation in patients after heart transplantation. (PubMed id 11527639)9 Weis M....von Scheidt W. (J. Am. Coll. Cardiol. 2001)
    569. Quantitative flow cytometry shows activation of the TNF-alpha system but not of the IL-2 system at the single cell level in renal replacement therapy. (PubMed id 11427636)9 van Riemsdijk-Van Overbeeke I.C....Weimar W. (Nephrol. Dial. Transplant. 2001)
    570. Deletion of the acidic-rich domain of the IL-2Rbeta chain increases receptor-associated PI3K activity. (PubMed id 11434934)9 CiprAcs A....MAcrida I. (FEBS Lett. 2001)
    571. Local immunotherapy of glioma patients with a combination of 2 bispecific antibody fragments and resting autologous lymphocytes: evidence for in situ t-cell activation and therapeutic efficacy. (PubMed id 11146449)9 Jung G....Wilmanns W. (Int. J. Cancer 2001)
    572. VLDL modulates the cytokine secretion profile to a proinflammatory pattern. (PubMed id 11444855)9 Sampedro M.C....Kivatinitz S.C. (Biochem. Biophys. Res. Commun. 2001)
    573. Cyclodextrin modulation of T lymphocyte signal transduction with aging. (PubMed id 11470130)9 FA1lAPp T....Dupuis G. (Mech. Ageing Dev. 2001)
    574. Hypercalcemia in a patient with B-cell acute lymphoblastic leukemia: a role of proinflammatory cytokine. (PubMed id 11523624)9 Fukasawa H....Hishida A. (Am. J. Med. Sci. 2001)
    575. Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor. (PubMed id 11509615)9 Moon J.J. and Nelson B.H. (J. Immunol. 2001)
    576. Lowered serum dipeptidyl peptidase IV activity is associated with depressive symptoms and cytokine production in cancer patients receiving interleukin-2-based immunotherapy. (PubMed id 11120395)9 Maes M....Neveu P.J. (Neuropsychopharmacology 2001)
    577. Gene expression profile of herpesvirus-infected T cells obtained using immunomicroarrays: induction of proinflammatory mechanisms. (PubMed id 11689646)9 Mayne M....Jacobson S. (J. Virol. 2001)
    578. [Antibodies and immunomodulation]. (PubMed id 11577588)9 Berthoux F. (Presse Med 2001)
    579. [Interleukin level in endogenous depression]. (PubMed id 11586704)9 Androsova L.V....Egorova M.I.u. (Zh Nevrol Psikhiatr Im S S Korsakova 2001)
    580. Interleukin-2 activates human peripheral blood eosinophils. (PubMed id 11520078)9 Hoenstein R....Levi-Schaffer F. (Cell. Immunol. 2001)
    581. Cytokine and immunogenetic profiles in Japanese patients with adult Still's disease. Association with chronic articular disease. (PubMed id 11752512)9 Fujii T....Mimori T. (Rheumatology (Oxford) 2001)
    582. Recurrence of hepatitis C after liver transplantation is associated with increased systemic IL-10 levels. (PubMed id 11324903)9 Sheiner P.A....Boros P. (Mediators Inflamm. 2001)
    583. IL-18 might reflect disease activity in mild and moderate asthma exacerbation. (PubMed id 11174201)9 Tanaka H....Abe S. (J. Allergy Clin. Immunol. 2001)
    584. Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle. (PubMed id 11313401)9 Zhang L.H. and Liu J.O. (J. Immunol. 2001)
    585. New therapeutic modalities in the treatment of graft-versus-host disease. (PubMed id 11311659)9 Basara N....Fauser A.A. (Crit. Rev. Oncol. Hematol. 2001)
    586. NK cells secrete high levels of IFN-gamma in response to in vivo administration of IL-2. (PubMed id 11745353)9 Thornton S....Hirsch R. (Eur. J. Immunol. 2001)
    587. CD4+CD25high regulatory cells in human peripheral blood. (PubMed id 11466340)9 Baecher-Allan C....Hafler D.A. (J. Immunol. 2001)
    588. Serum leptin levels in septic men correlate well with C-reactive protein (CRP) and TNF-alpha but not with BMI. (PubMed id 11829320)9 Maruna P....HaluzA-k M. (Physiol Res 2001)
    589. Effect of metoprolol on cytokine levels in chronic heart failure--a substudy in the Metoprolol Controlled-Release Randomised Intervention Trial in Heart Failure (MERIT-HF). (PubMed id 11231439)9 Gullestad L....Aukrust P. (Am. Heart J. 2001)
    590. Cytokine profile of patients with mycosis fungoides and the immunomodulatory effect of AS101. (PubMed id 11720171)9 Shohat M....David M. (Acta Derm. Venereol. 2001)
    591. Expression of nerve growth factor receptors and their prognostic value in human breast cancer. (PubMed id 11389056)9 Descamps S....Peyrat J.P. (Cancer Res. 2001)
    592. Nutritional status impairments in HIV-infected patients are associated with increased TNF-alpha and IL-6 serum levels but not with viral load. (PubMed id 11688902)9 Galhardo M.C....Sarno E.N. (Infection 2001)
    593. Persistent inflammation and immune activation contribute to cholestasis in patients receiving home parenteral nutrition. (PubMed id 11369168)9 Reimund J.M....Baumann R. (Nutrition 2001)
    594. Leptin as an acute phase reactant after non-adjustable laparoscopic gastric banding. (PubMed id 11594104)9 Maruna P....Haluzik M. (Obes Surg 2001)
    595. Synovial fluid cytokine levels in BehAset's disease. (PubMed id 11760396)9 Ertenli I....Kirazli S. (Clin. Exp. Rheumatol. 2001)
    596. Generalized Wegener's granulomatosis responding to sulfamethoxazole-trimethoprim monotherapy. (PubMed id 11506314)9 Ohtake T....Kimura M. (Intern. Med. 2001)
    597. Immunotherapy with interferon-alpha in patients affected by chronic hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in depressive and anxiety symptoms. (PubMed id 11740974)9 Bonaccorso S....Maes M. (Psychiatry Res 2001)
    598. Anergy and human immunodeficiency virus infection. (PubMed id 11359364)9 Hegde H.R. and Robbins S.M. (Med. Hypotheses 2001)
    599. Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. (PubMed id 11418279)9 Mikova O....Maes M. (Eur Neuropsychopharmacol 2001)
    600. Treatment of epidermolysis bullosa acquisita with the humanized anti-Tac mAb daclizumab. (PubMed id 11683573)9 Egan C.A....Yancey K.B. (Clin. Immunol. 2001)
    601. IL-15 and IL-2: a matter of life and death for T cells in vivo. (PubMed id 11135625)9 Li X.C....Strom T.B. (Nat. Med. 2001)
    602. Thiols decrease cytokine levels and down-regulate the expression of CD30 on human allergen-specific T helper (Th) 0 and Th2 cells. (PubMed id 11298119)9 Bengtsson A....Scheynius A. (Clin. Exp. Immunol. 2001)
    603. Interleukin-6 and the network of several cytokines in multiple myeloma: an overview of clinical and experimental data. (PubMed id 11741345)9 Lauta V.M. (Cytokine 2001)
    604. [Comparative study of the functional expression of the Na/K-pump in human lymphocytes, activated by phytohemagglutinin, phorbol ester, ionomycin, and interleukin-2]. (PubMed id 11347470)9 Toropova F.V....Marakhova I.I. (Tsitologiia 2001)
    605. Effect of immunosuppressive cladribine treatment on serum leucocytes system in two-year clinical trial in patients with chronic progressive multiple sclerosis. (PubMed id 11208501)9 Janiec K....Kondera-Anasz Z. (Med. Sci. Monit. 2001)
    606. Phase II trial of systemic recombinant interleukin-2 in the treatment of refractory nasopharyngeal carcinoma. (PubMed id 11244324)9 Chi K.H....Lotze M.T. (Oncology 2001)
    607. Soluble immunological parameters and early prognosis of renal cell cancer patients. (PubMed id 11876546)9 Kallio J.P....Kellokumpu-Lehtinen P.L. (amp 2001)
    608. Plasma concentrations of interleukin-1beta, interleukin-6, soluble interleukin-2 receptor and tumor necrosis factor alpha of depressed patients in Japan. (PubMed id 11174046)9 Kagaya A....Uchitomi Y. (Neuropsychobiology 2001)
    609. Kinetics of plasma cytokines after hematopoietic stem cell transplantation from unrelated donors: the ratio of plasma IL-10/sTNFR level as a potential prognostic marker in severe acute graft-versus-host disease. (PubMed id 11551026)9 Sakata N....Kawa K. (Bone Marrow Transplant. 2001)
    610. Low oxygen tension and autologous plasma enhance T-cell proliferation and CD49d expression density in serum-free media. (PubMed id 11953028)9 Haddad H. and Papoutsakis E.T. (Cytotherapy 2001)
    611. Interleukin 2 leads to dose-dependent expression of the alpha chain of the IL-2 receptor on CD25-negative T lymphocytes in the absence of exogenous antigenic stimulation. (PubMed id 11112366)9 Sereti I....Lane H.C. (Clin. Immunol. 2000)
    612. Diagnostic value of combined evaluation of neopterin and anti-DNA antibody levels for assessment of disease activity in systemic lupus erythematosus. (PubMed id 11138331)9 Nagy G....Gergely P. (Clin. Exp. Rheumatol. 2000)
    613. Inhibition of proliferation of human peripheral blood mononuclear cells by calcium antagonists. Role of interleukin-2. (PubMed id 10791290)9 Petrov V. and Lijnen P. (Methods Find Exp Clin Pharmacol 2000)
    614. Innate immune response of the human host to exposure with herpes simplex virus type 1: in vitro control of the virus infection by enhanced natural killer activity via interleukin-15 induction. (PubMed id 10906173)9 Ahmad A....Menezes J. (J. Virol. 2000)
    615. The role of calcineurin in lymphocyte activation. (PubMed id 10995587)9 Baksh S. and Burakoff S.J. (Semin. Immunol. 2000)
    616. Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis. (PubMed id 10954656)9 Krueger J.G....Gottlieb A.B. (J. Am. Acad. Dermatol. 2000)
    617. Clinical ineffectiveness of IL-2 and/or IFN alpha administration after autologous PBSC transplantation in pediatric oncological patients. (PubMed id 10689713)9 Vlk V....PospA-silovA! D. (Pediatr Hematol Oncol 2000)
    618. Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma. (PubMed id 10906027)9 Sahid El-Radhi A....Corrigan C.J. (Arch. Dis. Child. 2000)
    619. Progesterone enhances interleukin-15 production in human endometrial stromal cells in vitro. (PubMed id 11134140)9 Okada H....Kanzaki H. (J. Clin. Endocrinol. Metab. 2000)
    620. The effect of Daclizumab in a high-risk renal transplant population. (PubMed id 11048998)9 Meier-Kriesche H.U....Kaplan B. (Clin Transplant 2000)
    621. Epstein-Barr virus (EBV)-induced B-cell proliferative disorder after chemotherapy in a patient with hemophagocytic lymphohistiocytosis with associated EBV-induced T-cell proliferation. (PubMed id 11042520)9 Suzumiya J....Kikuchi M. (amp 2000)
    622. Lymphocyte activation after non-thermal trauma. (PubMed id 10671932)9 Walsh D.S....Webster H.K. (Br J Surg 2000)
    623. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway. (PubMed id 10982827)9 Gu H....Neel B.G. (Mol. Cell. Biol. 2000)
    624. Soluble antiapoptotic molecules and immune activation in chronic heart failure and unstable angina pectoris. (PubMed id 10821461)9 Fiorina P....Quaini F. (J. Clin. Immunol. 2000)
    625. An early experience with Simulect (basiliximab): an IL-2 receptor antibody. (PubMed id 11119913)9 Hinduja A....Kuruvilla S. (Transplant. Proc. 2000)
    626. Cytokine gene expression occurs more rapidly in stimulated peripheral blood mononuclear cells from human immunodeficiency virus-infected persons. (PubMed id 10973452)9 Breen E.C....Fahey J.L. (Clin. Diagn. Lab. Immunol. 2000)
    627. [A case of intravascular malignant lymphomatosis presenting as cerebral infarction]. (PubMed id 11127588)9 Satow T....Hayashino Y. (No Shinkei Geka 2000)
    628. Reduced expression of systemic proinflammatory cytokines after off-pump versus conventional coronary artery bypass grafting. (PubMed id 11145406)9 Schulze C....Wildhirt S.M. (Thorac Cardiovasc Surg 2000)
    629. Efficacy of Daclizumab in an African-American and Hispanic renal transplant population. (PubMed id 10836651)9 Meier-Kriesche H.U....Kaplan B. (Transpl. Int. 2000)
    630. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. (PubMed id 10679091)9 Lord J.D....Nelson B.H. (J. Immunol. 2000)
    631. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology. (PubMed id 11707860)9 Foss F.M. (Clin Lymphoma 2000)
    632. Distal procto-colitis and n-3 polyunsaturated fatty acids: the mechanism(s) of natural cytotoxicity inhibition. (PubMed id 10620003)9 Almallah Y.Z....Eremin O. (Eur. J. Clin. Invest. 2000)
    633. Surface membrane antigen alteration on blood basophils in patients with Hymenoptera venom allergy under immunotherapy. (PubMed id 11112905)9 Siegmund R....Herrmann D. (J. Allergy Clin. Immunol. 2000)
    634. In vitro release of interleukin-15 by broncho-alveolar lavage cells and peripheral blood mononuclear cells from patients with different lung diseases. (PubMed id 10705307)9 Zissel G....MA1ller-Quernheim J. (Eur. Cytokine Netw. 2000)
    635. Effect of parathyroid adenoma excision on interleukin-6 (IL-6) and IL-2 receptor levels. (PubMed id 10690943)9 Halabe A. and Shohat B. (Metab. Clin. Exp. 2000)
    636. Acute myelogenous leukemia blasts as accessory cells during in vitro T lymphocyte activation. (PubMed id 11161436)9 Bruserud O. and Ulvestad E. (Cell. Immunol. 2000)
    637. New strategies in the treatment of graft-versus-host disease. (PubMed id 10933179)9 Basara N....Fauser A.A. (Bone Marrow Transplant. 2000)
    638. Unexpected cytokines in serum of malignant melanoma patients during sequential biochemotherapy. (PubMed id 11051235)9 Grimm E.A....Buzaid A.C. (Clin. Cancer Res. 2000)
    639. Evidence of chronic inflammation in morphologically normal small intestine of cystic fibrosis patients. (PubMed id 10709733)9 Raia V....Londei M. (Pediatr. Res. 2000)
    640. Results of a dose-intense phase 1 study of a combination chemotherapy regimen with cisplatin and epidoxorubicin including medroxyprogesterone acetate and recombinant interleukin-2 in patients with inoperable primary lung cancer. (PubMed id 10746553)9 Mantovani G....Pisano A. (J. Immunother. 2000)
    641. Decreased in vitro production of interferon-gamma and interleukin-2 in whole blood of patients with schizophrenia during treatment. (PubMed id 10822342)9 Arolt V....Kirchner H. (Mol. Psychiatry 2000)
    642. Eosinophils and C4 predict clinical failure of combination immunotherapy with very low dose subcutaneous interleukin-2 and interferon in renal cell carcinoma patients. (PubMed id 10702820)9 Moroni M....Buzio C. (Haematologica 2000)
    643. Humoral immune response during coronary artery bypass grafting: A comparison of limited approach, &quot;off-pump&quot; technique, and conventional cardiopulmonary bypass. (PubMed id 11082370)9 Diegeler A....Mohr F.W. (Circulation 2000)
    644. The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation. (PubMed id 10701840)9 Schnaider T....Szamel M. (amp 2000)
    645. Procalcitonin in paediatric cancer patients: its diagnostic relevance is superior to that of C-reactive protein, interleukin 6, interleukin 8, soluble interleukin 2 receptor and soluble tumour necrosis factor receptor II. (PubMed id 11167745)9 Fleischhack G....Bode U. (Br. J. Haematol. 2000)
    646. [Modulation of cytokine production from human mononuclear cells by several agents]. (PubMed id 11193379)9 Yoshimura T. (Yakugaku Zasshi 2000)
    647. Influence of hormone replacement therapy and aspirin on temperature regulation in postmenopausal women. (PubMed id 10956241)9 Brooks-Asplund E.M....Kenney W.L. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000)
    648. Hormonal changes in brain death and immune activation in the donor. (PubMed id 11112013)9 Lopau K....Wanner C. (Transpl. Int. 2000)
    649. Rescue of human T cells by interleukin-9 (IL-9) from IL-2 deprivation-induced apoptosis: correlation with alpha subunit expression of the IL-9 receptor. (PubMed id 10888117)9 Perdow-Hickman S. and Salgame P. (amp 2000)
    650. Macrophage-mediated immunostimulation modulates therapeutic efficacy of interleukin-2 based chemoimmunotherapy in advanced metastatic melanoma patients. (PubMed id 10711641)9 Bernengo M.G....Fierro M.T. (Melanoma Res. 2000)
    651. Daclizumab prevents acute rejection and improves patient survival post transplantation: 1 year pooled analysis. (PubMed id 10836653)9 Ekberg H....Vincenti F. (Transpl. Int. 2000)
    652. Subunit structure of the high and low affinity human interleukin-15 receptors. (PubMed id 10903799)9 Lehours P....Jacques Y. (Eur. Cytokine Netw. 2000)
    653. Simultaneous peripubertal onset of multireactive autoimmune diseases with an unusual long-lasting remission of type 1 diabetes mellitus. (PubMed id 11106928)9 Valerio G....Pignata C. (Clin. Endocrinol. (Oxf) 2000)
    654. Avoidance of cyclosporine in renal transplantation: effects of daclizumab, mycophenolate mofetil, and steroids. (PubMed id 11004222)9 Tran H.T....Milford E.L. (J. Am. Soc. Nephrol. 2000)
    655. Development and validation of an immunoreceptor assay for simulect based on surface plasmon resonance. (PubMed id 10527499)9 Deckert F. and Legay F. (Anal. Biochem. 1999)
    656. [Effect of -6 degrees head-down-bed-rest on human cellular immune function]. (PubMed id 11765771)9 Wen X.L....Duan Y.R. (amp 1999)
    657. Improvement of lymphocyte proliferation in human immunodeficiency virus infection after recombinant interleukin-2 treatment. (PubMed id 10576122)9 Afzelius P....Hansen J.E. (Scand. J. Infect. Dis. 1999)
    658. Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis. (PubMed id 10504009)9 Haack M....PollmAocher T. (J Psychiatr Res 1999)
    659. [Unusual case of disseminated sarcoidosis with prominent gastrointestinal symptoms]. (PubMed id 9987484)9 Klebl F.H....Palitzsch K.D. (Dtsch. Med. Wochenschr. 1999)
    660. Reduction of acute renal allograft rejection by daclizumab. Daclizumab Double Therapy Study Group. (PubMed id 9921806)9 Nashan B....Johnson J.R. (Transplantation 1999)
    661. Effects of interferon-alpha2a treatment on serum levels of tumor necrosis factor-alpha, tumor necrosis factor-alpha2 receptor, interleukin-2, interleukin-2 receptor, and E-selectin in BehAset's disease. (PubMed id 10651074)9 Kosar A....DA1ndar S. (Rheumatol. Int. 1999)
    662. Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver. (PubMed id 10228796)9 Zaloudik J....Sheard M. (Hepatogastroenterology 1999)
    663. IL-4 inhibits human CD8 T cell expression of the common IL-2 receptor gamma chain. (PubMed id 10224467)9 Vyas B....Kemeny D.M. (Int. Arch. Allergy Immunol. 1999)
    664. Elevated immunoglobulin E (IgE) levels in children with exposure to environmental lead. (PubMed id 10413189)9 Lutz P.M....Hewett J.E. (Toxicology 1999)
    665. [Progressive systemic sclerosis - treatment results of extracorporeal photopheresis]. (PubMed id 10501679)9 Wollina U....Vogelsang H. ( Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1999)
    666. Modulation of coronary vasomotor tone by cytokines in cardiac transplant recipients. (PubMed id 10573061)9 Weis M....von Scheidt W. (Transplantation 1999)
    667. Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator. (PubMed id 9893120)9 Sitter T....Kooistra T. (Kidney Int. 1999)
    668. Markers of systemic inflammation predicting organ failure in community-acquired septic shock. (PubMed id 10545303)9 Takala A....Repo H. (Clin. Sci. 1999)
    669. Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events. (PubMed id 10202570)9 Maes M....Bosmans E. (Biol. Psychiatry 1999)
    670. Cisplatin at clinically relevant concentrations enhances interleukin-2 synthesis by human primary blood lymphocytes. (PubMed id 10211553)9 Riesbeck K. (Anticancer Drugs 1999)
    671. Daclizumab: a review of its use in the prevention of acute rejection in renal transplant recipients. (PubMed id 10651389)9 Wiseman L.R. and Faulds D. (Drugs 1999)
    672. Signalling events mediating the activation of protein kinase C by interleukin-2 in cytotoxic T cells. (PubMed id 10372805)9 Lu Y....Durkin J.P. (Cell. Signal. 1999)
    673. Cytokine profile of HIV-positive Kaposi's sarcoma derived cells in vitro. (PubMed id 10085275)9 Brockmeyer N.H....StA1rzl M. (Eur. J. Med. Res. 1999)
    674. Immobilization of glycosylphosphatidylinositol-anchored proteins inhibits T cell growth but not function. (PubMed id 10464159)9 Marmor M.D....Julius M. (Int. Immunol. 1999)
    675. Suppression of atherosclerotic development in Watanabe heritable hyperlipidemic rabbits treated with an oral antiallergic drug, tranilast. (PubMed id 10027816)9 Matsumura T....Yasue H. (Circulation 1999)
    676. Perioperative serum levels of tumour-necrosis-factor alpha (TNF-alpha), IL-1 beta, IL-6, IL-10 and soluble IL-2 receptor in patients undergoing cardiac surgery with cardiopulmonary bypass without and with correction for haemodilution. (PubMed id 10540185)9 Roth-Isigkeit A....Schmucker P. (Clin. Exp. Immunol. 1999)
    677. Role of zinc and alpha2 macroglobulin on thymic endocrine activity and on peripheral immune efficiency (natural killer activity and interleukin 2) in cervical carcinoma. (PubMed id 9888464)9 Mocchegiani E....Garzetti G.G. (Br. J. Cancer 1999)
    678. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. (PubMed id 10358752)9 Waldmann T.A. and Tagaya Y. (Annu. Rev. Immunol. 1999)
    679. Modulatory effect of a serine protease inhibitor on surgical stress: its clinical implications. (PubMed id 10561733)9 Iwagaki H....Tanaka N. (Acta Med. Okayama 1999)
    680. Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor. (PubMed id 10197798)9 Harris D.T....Pastan I. (Bone Marrow Transplant. 1999)
    681. Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. (PubMed id 10516077)9 Collins N.D....Lairmore M.D. (J. Virol. 1999)
    682. Intravascular lymphomatosis presenting as an ascending cauda equina: conus medullaris syndrome: remission after biweekly CHOP therapy. (PubMed id 10449569)9 Nakahara T....Yamamoto T. (J. Neurol. Neurosurg. Psychiatr. 1999)
    683. Serum granulocyte colony-stimulating factor kinetics in children receiving intense chemotherapy with or without stem cell support. (PubMed id 10417053)9 Saito S....Takaue Y. (J Hematother 1999)
    684. Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain. (PubMed id 10075926)9 Cacalano N.A....Johnston J.A. (EMBO J. 1999)
    685. Long-term follow-up of cytokines and soluble cytokine receptors in peripheral blood of patients with juvenile rheumatoid arthritis. (PubMed id 10505742)9 Mangge H....Schauenstein K. (amp 1999)
    686. Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. (PubMed id 10090941)9 Kolenko V....Finke J. (Blood 1999)
    687. Selective proteolytic cleavage of IL-2 receptor and IL-6 receptor ligand binding chains by neutrophil-derived serine proteases at foci of inflammation. (PubMed id 10574621)9 Bank U....Ansorge S. (amp 1999)
    688. The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2. (PubMed id 9796831)9 Hu H.Y....vanderSpek J.C. (Protein Eng. 1998)
    689. Multiple sclerosis: IL-2 and sIL-2R levels in cerebrospinal fluid and serum. Review of literature and critical analysis of ELISA pitfalls. (PubMed id 9532585)9 Sivieri S....Gallo P. (Mult. Scler. 1998)
    690. [The significance of cytokines in the early diagnosis of postoperative intraabdominal sepsis]. (PubMed id 9658957)9 GA1rlich R....CermA!k J. (Rozhl Chir 1998)
    691. Cytokine expression and molecular mechanisms of their auto/paracrine regulation of anterior pituitary function and growth. (PubMed id 9629279)9 Arzt E....Stalla G.K. (Ann. N. Y. Acad. Sci. 1998)
    692. Dysregulation of interleukin-2 receptor beta and interleukin-2 receptor gamma expression during HIV infection. (PubMed id 9831196)9 David D....ThA"ze J. (Eur. Cytokine Netw. 1998)
    693. [The importance of determination of interleukin-10 in the blood of patients with systemic lupus erythematosus]. (PubMed id 9511265)9 Scudla V....HermanovA! Z. (Cas. Lek. Cesk. 1998)
    694. Proteolytic cleavage of CD25, the alpha subunit of the human T cell interleukin 2 receptor, by Der p 1, a major mite allergen with cysteine protease activity. (PubMed id 9432986)9 Schulz O....Shakib F. (J. Exp. Med. 1998)
    695. Molecular characterization of the signal responsible for the targeting of the interleukin 2 receptor beta chain toward intracellular degradation. (PubMed id 9792646)9 Subtil A....Dautry-Varsat A. (J. Biol. Chem. 1998)
    696. Serum cytokine levels after HLA-identical bone marrow transplantation. (PubMed id 9798695)9 Liem L.M....Goulmy E. (Transplantation 1998)
    697. Molecular analysis of the IL-2 receptor beta chain gene expressed in human tumor cells. (PubMed id 9546432)9 Suminami Y....Whiteside T.L. (Oncogene 1998)
    698. Functional and physical association of a cell surface phospholipid and interleukin-2 receptor p55(alpha) subunits. (PubMed id 9804890)9 Saragovi H.U....ThAcze J. (Biochim. Biophys. Acta 1998)
    699. Immune response and cytokines in septic rats undergoing blood transfusion. (PubMed id 9878327)9 Salinas J.C....Lozano R. (J. Surg. Res. 1998)
    700. Molecular cloning and expression of feline interleukin-16. (PubMed id 9773277)9 Leutenegger C.M....Lutz H. (DNA Seq. 1998)
    701. Cytokine gene expression in normal human lymphocytes in response to stimulation. (PubMed id 9605988)9 Fan J....Fahey J.L. (Clin. Diagn. Lab. Immunol. 1998)
    702. Immunomodulatory effects of IL-12 in relation to the pineal endocrine function in metastatic cancer patients. (PubMed id 11061586)9 Lissoni P....MandalA M. (Nat. Immun. 1998)
    703. Circulating levels of IL-1beta, IL-6 and soluble IL-2 receptor in polymyalgia rheumatica and giant cell arteritis and rheumatoid arthritis. (PubMed id 9714363)9 Pountain G....Cawston T.E. (Br. J. Rheumatol. 1998)
    704. Interleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans. (PubMed id 9423851)9 VA!zquez N....Lyman C.A. (Infect. Immun. 1998)
    705. The Hsp90-specific inhibitor, geldanamycin, blocks CD28-mediated activation of human T lymphocytes. (PubMed id 9747895)9 Schnaider T....Szamel M. (Life Sci. 1998)
    706. DAB389IL2 diphtheria fusion toxin produces clinical responses in tumor stage cutaneous T cell lymphoma. (PubMed id 9590158)9 Duvic M....Frankel A.E. (Am. J. Hematol. 1998)
    707. Interleukin-15 and its role in chronic inflammatory diseases. (PubMed id 9719492)9 Kirman I....Nielsen O.H. (Inflamm. Res. 1998)
    708. Immunophenotypic profile of peripheral blood eosinophils in acute graft-vs.-host disease. (PubMed id 9472806)9 Rumi C....Leone G. (Exp. Hematol. 1998)
    709. [Expression of IL-2 receptor in peripheral blood lymphocytes and bronchoalveolar lavage fluid (BAL) in patients with sarcoidosis]. (PubMed id 9686498)9 Koktysz M....RoliA8ski J. (Pol. Arch. Med. Wewn. 1998)
    710. Cells and cytokines in pollinosis. (PubMed id 9823418)9 Carlos A.G....Melo A. (Allerg Immunol (Paris) 1998)
    711. Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma. (PubMed id 9600494)9 Chan M.T....Spahn J.D. (J. Allergy Clin. Immunol. 1998)
    712. Biological agents in rheumatoid arthritis: which ones could be used in combination? (PubMed id 18020567)9 Lorenz M. and Kalden J.R. (BioDrugs 1998)
    713. Increased eosinophil activity in acute Plasmodium falciparum infection--association with cerebral malaria. (PubMed id 9649195)9 Kurtzhals J.A....Hviid L. (Clin. Exp. Immunol. 1998)
    714. B-lymphocyte proliferation during bovine leukemia virus-induced persistent lymphocytosis is enhanced by T-lymphocyte-derived interleukin-2. (PubMed id 9525643)9 Trueblood E.S....McElwain T.F. (J. Virol. 1998)
    715. Is malnutrition overdiagnosed in older hospitalized patients? Association between the soluble interleukin-2 receptor and serum markers of malnutrition. (PubMed id 9520912)9 Rosenthal A.J....Adler R.A. (J. Gerontol. A Biol. Sci. Med. Sci. 1998)
    716. Treatment of multiple sclerosis with copolymer-1 (Copaxone): implicating mechanisms of Th1 to Th2/Th3 immune-deviation. (PubMed id 9916886)9 Miller A....Lahat N. (J. Neuroimmunol. 1998)
    717. Perioperative cytokine release during coronary artery bypass grafting in patients of different ages. (PubMed id 9764599)9 Roth-Isigkeit A....Seyfarth M. (Clin. Exp. Immunol. 1998)
    718. Interleukins and their antagonists but not TNF and its receptors are released in post-ERP pancreatitis. (PubMed id 9855088)9 Messmann H....SchAPlmerich J. (amp 1998)
    719. Increased serum levels of interleukin (IL)-5, IL-6 and IL-8 in bullous pemphigoid. (PubMed id 9459128)9 Inaoki M. and Takehara K. (J. Dermatol. Sci. 1998)
    720. Generation of cytokine-induced killer cells using exogenous interleukin-2, -7 or -12. (PubMed id 9875675)9 Zoll B....Schmidt-Wolf I.G. (Cancer Immunol. Immunother. 1998)
    721. Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling. (PubMed id 9802969)9 Haughn L....Julius M. (J. Exp. Med. 1998)
    722. Antitumor activity of DAB389IL-2 fusion toxin in mycosis fungoides. (PubMed id 9674399)9 Saleh M.N....Nichols J.C. (J. Am. Acad. Dermatol. 1998)
    723. The use of antibodies against the IL-2 receptor in transplantation. (PubMed id 9794841)9 Waldmann T.A. and O'Shea J. (Curr. Opin. Immunol. 1998)
    724. Effects of chromium extract on cytokine release by mononuclear cells. (PubMed id 9678877)9 Granchi D....Pizzoferrato A. (Biomaterials 1998)
    725. Correlation between DNA content, expression of Ki-67 antigen of tumor cells and immunophenotype of lymphocytes from malignant pleural effusions. (PubMed id 9591046)9 Sikora J....Zeromski J. (Tumour Biol. 1998)
    726. IL-7-dependent extrathymic expansion of CD45RA+ T cells enables preservation of a naive repertoire. (PubMed id 9834071)9 Soares M.V....Akbar A.N. (J. Immunol. 1998)
    727. Human hematopoietic cell express two forms of the cytokine receptor common gamma-chain (gamma c). (PubMed id 9444398)9 Shi Y.F....Mills G.B. (Cell Res. 1997)
    728. IL-15 is chemotactic for natural killer cells and stimulates their adhesion to vascular endothelium. (PubMed id 9201264)9 Allavena P....Mantovani A. (J. Leukoc. Biol. 1997)
    729. In vitro interleukin 12 activation of peripheral blood CD3(+)CD56(+) and CD3(+)CD56(-) gammadelta T cells from glioblastoma patients. (PubMed id 9815731)9 Fujimiya Y....Ebina T. (Clin. Cancer Res. 1997)
    730. Growth factor receptors: structure, mechanism, and drug discovery. (PubMed id 9566117)9 McInnes C. and Sykes B.D. (Biopolymers 1997)
    731. Tumor-induced suppression of T lymphocyte proliferation coincides with inhibition of Jak3 expression and IL-2 receptor signaling: role of soluble products from human renal cell carcinomas. (PubMed id 9300731)9 Kolenko V....Finke J. (J. Immunol. 1997)
    732. Expression of cytokine receptors on follicular dendritic cells. (PubMed id 9389700)9 Yamada K....Tsukamoto M. (Blood 1997)
    733. Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporin A and rapamycin. (PubMed id 9237106)9 Valentine J.E. and Sewell W.A. (Int. Immunol. 1997)
    734. Evidence for reduced Th1 function in normal pregnancy: a hypothesis for the remission of rheumatoid arthritis. (PubMed id 9195507)9 Russell A.S....Maksymowych W.P. (J. Rheumatol. 1997)
    735. Tumor-associated lympho-monocytes from neoplastic effusions are immunologically defective in comparison with patient autologous PBMCs but are capable of releasing high amounts of various cytokines. (PubMed id 9180137)9 Mantovani G....Del Giacco G.S. (Int. J. Cancer 1997)
    736. Interactions of the Alzheimer beta amyloid fragment (25-35) with peripheral blood dendritic cells. (PubMed id 9147374)9 Schmitt T.L....Grubeck-Loebenstein B. (Mech. Ageing Dev. 1997)
    737. Establishment and characterization of a new, factor-independent acute myeloid leukemia line designated Ei501. (PubMed id 9180296)9 Weidmann E....Bergmann L. (Leukemia 1997)
    738. A double-blind, placebo-controlled, crossover therapy study with natural human IL-2 (nhuIL-2) in combination with regular intravenous gammaglobulin (IVIG) infusions in 10 patients with common variable immunodeficiency (CVID). (PubMed id 9367398)9 Rump J.A....Peter H.H. (Clin. Exp. Immunol. 1997)
    739. A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor. (PubMed id 9407092)9 RydAcn M. and IbA!A+ez C.F. (J. Biol. Chem. 1997)
    740. Fip-vvo, a new fungal immunomodulatory protein isolated from Volvariella volvacea. (PubMed id 9163352)9 Hsu H.C....Lin J.Y. (Biochem. J. 1997)
    741. Relationship of plasma HIV-RNA levels and levels of TNF-alpha and immune activation products in HIV infection. (PubMed id 9191882)9 Salazar-Gonzalez J.F....Fahey J.L. (Clin. Immunol. Immunopathol. 1997)
    742. Regulation of IL-2 signaling. (PubMed id 9209410)9 Higuchi M....Sugamura K. (Leukemia 1997)
    743. Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-alpha (TNF-alpha) receptors in type C chronic liver disease. (PubMed id 9328122)9 Kakumu S....Yoshika Y. (Clin. Exp. Immunol. 1997)
    744. A comparative study of the in vitro immunomodulatory activity of human intact immunoglobulin (7S IVIG), F(ab')2 fragments (5S IVIG) and Fc fragments. Evidence for post-transcriptional IL-2 modulation. (PubMed id 9135549)9 Nachbaur D....Niederwieser D. (Immunology 1997)
    745. Alterations of the cytokine network in patients undergoing cardiopulmonary bypass. (PubMed id 9413852)9 Sablotzki A....Hempelmann G. (Perfusion 1997)
    746. [Prevention and treatment of seasonal asthmatic patients by combined invigorating kidney for preventing asthma tablets and beclomethasone dipropinate]. (PubMed id 10322818)9 Xu D. and Xu R.H. (Zhongguo Zhong Xi Yi Jie He Za Zhi 1997)
    747. In vivo immunomodulatory effects of clozapine in schizophrenia. (PubMed id 9323354)9 Maes M....Meltzer H.Y. (Schizophr. Res. 1997)
    748. Retinoic acid-induced modulation of IL-2 mRNA production and IL-2 receptor expression on T cells. (PubMed id 9130512)9 Ballow M....Rich G. (Int. Arch. Allergy Immunol. 1997)
    749. Potentialization of IL-2 effects on immune cells by oyster extract (JCOE) in normal and HIV-infected individuals. (PubMed id 9863500)9 Achour A....Zagury D. (amp 1997)
    750. A high serum concentration of interleukin-6 is predictive of relapse in quiescent Crohn's disease. (PubMed id 9391781)9 Louis E....Mary J.Y. (amp 1997)
    751. Malignant histiocytosis-like B-cell lymphoma, a distinct pathologic variant of intravascular lymphomatosis: a report of five cases and review of the literature. (PubMed id 9401080)9 Murase T....Saito H. (Br. J. Haematol. 1997)
    752. Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome. (PubMed id 9242543)9 Agostini C....Semenzato G. (Blood 1997)
    753. Interleukin 4 responses in acute leukaemia patients with severe chemotherapy-induced leucopenia. (PubMed id 9414637)9 Bruserud O....Nesthus I. (Eur. J. Haematol. 1997)
    754. IL-2-induced IL-5 synthesis, but not proliferation, of human CD4+ T cells is suppressed by FK506. (PubMed id 9103428)9 Mori A....Okudaira H. (J. Immunol. 1997)
    755. A selective impairment of the IL-2 system in lymphocytes of patients with glioblastomas: increased level of soluble IL-2R and reduced protein tyrosine phosphorylation. (PubMed id 9326745)9 Ashkenazi E....Brodie C. (Neuroimmunomodulation 1997)
    756. Common variable immunodeficiency with CD4+ T lymphocytopenia and overproduction of soluble IL-2 receptor associated with Turner's syndrome and dorsal kyphoscoliosis. (PubMed id 9462277)9 al-Attas R.A....Ahmed el-FE . (J. Clin. Pathol. 1997)
    757. Microtubule depolymerization inhibits clathrin coated-pit internalization in non-adherent cell lines while interleukin 2 endocytosis is not affected. (PubMed id 9410882)9 Subtil A. and Dautry-Varsat A. (J. Cell. Sci. 1997)
    758. Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases. (PubMed id 8977222)9 Guex-Crosier Y....Roberge F.G. (J. Immunol. 1997)
    759. Interleukin-15 (IL-15) induces IL-8 and monocyte chemotactic protein 1 production in human monocytes. (PubMed id 9326248)9 Badolato R....Musso T. (Blood 1997)
    760. Expression of interleukin 15 (IL-15) in human rhabdomyosarcoma, osteosarcoma and Ewing's sarcoma. (PubMed id 9180138)9 Lollini P.L....Nanni P. (Int. J. Cancer 1997)
    761. Interleukin 2 induces a transient downregulation of protein phosphatase 1 and 2A activity in human T cells. (PubMed id 9098929)9 Brockdorff J....Odum N. (Tissue Antigens 1997)
    762. Interleukin-15 triggers the proliferation and cytotoxicity of granular lymphocytes in patients with lymphoproliferative disease of granular lymphocytes. (PubMed id 8978293)9 Zambello R....Semenzato G. (Blood 1997)
    763. Serum-soluble IL-2 receptor and IL-6 levels in patients with melanoma. (PubMed id 9260602)9 Boyano M.D....DA-az-PAcrez J.L. (Oncology 1997)
    764. Plasma levels of cytokines and soluble cytokine receptors during treatment with haloperidol. (PubMed id 9396961)9 PollmAocher T....Mullington J. (Am J Psychiatry 1997)
    765. Neopterin, soluble IL-2 receptor and IL-6 secretion during IL-2 cancer immunotherapy: prognostic significance in relation to IL-12 variations. (PubMed id 9479598)9 Lissoni P....Fumagalli L. (Int. J. Biol. Markers 1997)
    766. Flow cytometric analysis of lymphocytes in cerebrospinal fluid in patients with tick-borne encephalitis. (PubMed id 9048982)9 Tomazic J. and Ihan A. (Acta Neurol. Scand. 1997)
    767. Increased serum levels of interleukin-1beta in the systemic circulation of patients with essential hypertension: additional risk factor for atherogenesis in hypertensive patients? (PubMed id 9042815)9 Dalekos G.N....Siamopoulos K.C. (J. Lab. Clin. Med. 1997)
    768. An extract of the fern Polypodium leucotomos inhibits human peripheral blood mononuclear cells proliferation in vitro. (PubMed id 9226474)9 Rayward J....Alvarez-Mon M. (Int. J. Immunopharmacol. 1997)
    769. [Cellular immunity in childhood iron deficiency anemia with recurrent respiratory infections]. (PubMed id 15625892)9 Liu W....Guo C. (Zhonghua Xue Ye Xue Za Zhi 1997)
    770. Selective expression of the interleukin-2 gene discriminates between the auto- and allo-mixed lymphocyte reaction. (PubMed id 9106332)9 Moudgil A....Jordan S.C. (Transpl. Immunol. 1997)
    771. The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals. (PubMed id 9192665)9 Chen M....O'Shea J.J. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    772. Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response. (PubMed id 9028322)9 Ross M.E. and Caligiuri M.A. (Blood 1997)
    773. IL-6 is a survival prognostic factor in renal cell carcinoma. (PubMed id 9271323)9 Thiounn N....DebrAc B. (Immunol. Lett. 1997)
    774. Host defensive, immunological, and microbiological observations of an early-onset periodontitis patient with virus-associated hemophagocytic syndrome. (PubMed id 9444599)9 Kono T....Murayama Y. (J. Periodontol. 1997)
    775. [Liver transplantation and splenectomy in idiopathic portal hypertension]. (PubMed id 9265393)9 Petrowsky H....Markus B.H. (Z Gastroenterol 1997)
    776. Interleukin-15 protects from lethal apoptosis in vivo. (PubMed id 9334724)9 Bulfone-Paus S....Kunzendorf U. (Nat. Med. 1997)
    777. Clinical value of cytokine antagonists in infectious complications. (PubMed id 9178365)9 Iwagaki H....Tanaka N. (Res. Commun. Mol. Pathol. Pharmacol. 1997)
    778. Adjuvant immunotherapy in malignant melanoma: impact of antibody formation against interferon-alpha on immunoparameters in vivo. (PubMed id 9181459)9 Davis-Daneshfar A....Dummer R. (J. Immunother. 1997)
    779. Modeling the proliferative response of T cells to IL-2 and IL-4. (PubMed id 9184697)9 Burke M.A....Morel P.A. (Cell. Immunol. 1997)
    780. Serum cytokine profiles in acute primary HIV-1 infection and in infectious mononucleosis. (PubMed id 8599886)9 Biglino A....Gioannini P. (Clin. Immunol. Immunopathol. 1996)
    781. IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain. (PubMed id 8624802)9 Wang H.Y....Keegan A.D. (Immunity 1996)
    782. Investigations of cytokine production in whole blood cultures of paranoid and residual schizophrenic patients. (PubMed id 8863007)9 Wilke I....Kirchner H. (Eur Arch Psychiatry Clin Neurosci 1996)
    783. Differential expression of ICAM-1 and LFA-1 versus L-selectin and VCAM-1 in autoimmune insulitis of NOD mice and association with both Th1- and Th2-type infiltrates. (PubMed id 8933279)9 Martin S....Kolb H. (J. Autoimmun. 1996)
    784. Differential regulation of interleukin-12- and interleukin-15-induced natural killer cell activation by interleukin-4. (PubMed id 8921963)9 Salvucci O....Chouaib S. (Eur. J. Immunol. 1996)
    785. Expression of IL-2 receptor beta-chain in B16 melanoma cells. (PubMed id 9087807)9 Garcia De Galdeano A....CaA+avate M.L. (Int. J. Dev. Biol. 1996)
    786. Human gamma delta T cell subset-proliferative response to malarial antigen in vitro depends on CD4+ T cells or cytokines that signal through components of the IL-2R. (PubMed id 8757332)9 Elloso M.M....Weidanz W.P. (J. Immunol. 1996)
    787. Structure of the fab fragment of SDZ CHI621: a chimeric antibody against CD25. (PubMed id 15299676)9 Mikol V. (Acta Crystallogr. D Biol. Crystallogr. 1996)
    788. Interactions of tunicate immunomodulatory proteins with mammalian cells. (PubMed id 8934650)9 Raftos D. (Immunol. Cell Biol. 1996)
    789. Prognostic significance of immunological evaluation in colorectal cancer. (PubMed id 10851496)9 Berghella A.M....Casciani C.U. (amp 1996)
    790. Peripheral T cell activation in long-term renal transplant patients: concordant upregulation of adhesion molecules and cytokine gene transcription. (PubMed id 8959642)9 Kern F....Reinke P. (J. Am. Soc. Nephrol. 1996)
    791. Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer. (PubMed id 10851498)9 Contasta I....Casciani C.U. (amp 1996)
    792. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. (PubMed id 8631883)9 Lin J.-X.... Leonard W.J. (J. Biol. Chem. 1996)
    793. Immunomodulatory action of levofloxacin on cytokine production by human peripheral blood mononuclear cells. (PubMed id 8957581)9 Yoshimura T....Nagai H. (Chemotherapy 1996)
    794. Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes. (PubMed id 8896219)9 Davis W.C....Bohach G.A. (Vet. Immunol. Immunopathol. 1996)
    795. Blockade of multiple costimulatory receptors induces hyporesponsiveness: inhibition of CD2 plus CD28 pathways. (PubMed id 8878397)9 Woodward J.E....Baliga P. (Transplantation 1996)
    796. Cell culture observations of human postnatal thymic epithelium: an in vitro model for growth and humoral influence on intrathymic T lymphocyte maturation. (PubMed id 8899432)9 Bodey B....Kaiser H.E. (In Vivo 1996)
    797. Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs. (PubMed id 8919323)9 Maes M....Meltzer H.Y. (Acta Psychiatr Scand 1996)
    798. Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. (PubMed id 8639878)9 MrA^zek E....Caligiuri M.A. (Blood 1996)
    799. Convergence of signaling transduced by prolactin (PRL)/cytokine chimeric receptors on PRL-responsive gene transcription. (PubMed id 8721989)9 Ferrag F....Kelly P.A. (Mol. Endocrinol. 1996)
    800. T-lymphocyte differentiation and proliferation in the absence of the cytoplasmic tail of the common cytokine receptor gamma c chain in a severe combined immune deficiency X1 patient. (PubMed id 8781427)9 Morelon E....de Saint Basile G. (Blood 1996)
    801. Cytokines in BehAset's disease. (PubMed id 8882039)9 Sayinalp N....Kirazli S. (J. Rheumatol. 1996)
    802. Role of prolactin in the modulation of NK and LAK cell activity after short- or long-term morphine administration in neoplastic patients. (PubMed id 9080251)9 Provinciali M....Fabris N. (Int. J. Immunopharmacol. 1996)
    803. Phase I study of subcutaneously administered interleukin-2 in combination with interferon alfa-2a in patients with advanced cancer. (PubMed id 8708712)9 Gause B.L....Longo D.L. (J. Clin. Oncol. 1996)
    804. Immune system of cold-exposed and cold-adapted humans. (PubMed id 8925815)9 JanskA1 L....KamA-nkovA! J. (Eur J Appl Physiol Occup Physiol 1996)
    805. IL-4 down-regulates the responsiveness of human intraepithelial lymphocytes. (PubMed id 8809149)9 Ebert E.C. and Roberts A.I. (Clin. Exp. Immunol. 1996)
    806. An upregulation of interleukin-2 receptor, transferrin receptor expression and cytokine production mediated by hemin in human peripheral blood mononuclear cells. (PubMed id 8776616)9 Tsuji A....Nakamura H. (Int. J. Urol. 1996)
    807. Immunological studies of herpes simplex virus infection in children with atopic eczema. (PubMed id 8745891)9 Goodyear H.M....Harper J.I. (Br. J. Dermatol. 1996)
    808. Interleukin-15 gene expression in human astrocytes and microglia in culture. (PubMed id 8804052)9 Lee Y.B....Kim S.U. (Neuroreport 1996)
    809. Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the gamma-c gene. (PubMed id 8605323)9 Taylor N....Weinberg K. (Blood 1996)
    810. Lymphocyte activation and cytokine production in autoimmune hemolytic anaemia (AIHA). (PubMed id 9020407)9 Fagiolo E. and Abenante L. (Autoimmunity 1996)
    811. Serum cytokine and anti-Fc gamma R autoantibody measurements in patients with systemic sclerosis. (PubMed id 8721484)9 Szegedi A....Boros P. (Acta Derm. Venereol. 1996)
    812. Clonal and functional analysis for the augmentation of tumour-infiltrating lymphocytes by interleukin 4. (PubMed id 8855979)9 Tsunoda T....Arii K. (Br. J. Cancer 1996)
    813. Different immunophenotype and autoantibody production by peripheral blood and thyroid-derived lymphocytes in patients with Graves' disease. (PubMed id 8750571)9 Aust G....Heberling H.J. (amp 1996)
    814. Incidence and in-vivo relevance of anti-interferon antibodies during treatment of low-grade cutaneous T-cell lymphomas with interferon alpha-2a combined with acitretin or PUVA. (PubMed id 8874750)9 Rajan G.P....Dummer R. (Arch. Dermatol. Res. 1996)
    815. Rationale and clinical results of using leucocyte-derived immunosupportive therapies in HIV disease. (PubMed id 8993754)9 Gottlieb A.A....Kern C.H. (Biotherapy 1996)
    816. Interaction of IL-15 with the shared IL-2 receptor beta and gamma c subunits. The IL-15/beta/gamma c receptor-ligand complex is less stable than the IL-2/beta/gamma c receptor-ligand complex. (PubMed id 8568232)9 de Jong J.L....Sondel P.M. (J. Immunol. 1996)
    817. Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex. (PubMed id 8734356)9 Kennedy M.K. and Park L.S. (J. Clin. Immunol. 1996)
    818. IL-2 receptor gamma chain expression on CD34 positive hematopoietic progenitor cells from bone marrow and cord blood. (PubMed id 8804156)9 Itano M....Konno T. (Tohoku J. Exp. Med. 1996)
    819. Phase I/IB study of polyadenylic-polyuridylic acid in patients with advanced malignancies: clinical and biologic effects. (PubMed id 8877734)9 Witt P.L....Borden E.C. (amp 1996)
    820. Age-related tyrosine-specific protein phosphorylation defect in human T lymphocytes activated through CD3, CD4, CD8 or the IL-2 receptor. (PubMed id 8819096)9 Quadri R.A....Proust J.J. (Mech. Ageing Dev. 1996)
    821. Immune and nutritional effects of early enteral nutrition after major abdominal operations. (PubMed id 8639722)9 Braga M....Carlo V.D. (Eur J Surg 1996)
    822. Early calcium signaling and calcium requirements for the IL-2 receptor expression and IL-2 production in stimulated lymphocytes. (PubMed id 8912879)9 Komada H....Izutsu K. (Cell. Immunol. 1996)
    823. Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells. (PubMed id 8890166)9 Tagaya Y....Waldmann T.A. (EMBO J. 1996)
    824. The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. (PubMed id 8552611)9 Lai S.Y....Goldsmith M.A. (Proc. Natl. Acad. Sci. U.S.A. 1996)
    825. Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction. (PubMed id 8698387)9 Strickland D....Holt P.G. (Immunology 1996)
    826. Interleukin-15 up-regulates interleukin-2 receptor alpha chain but down-regulates its own high-affinity binding sites on human T and B cells. (PubMed id 8647198)9 Kumaki S....Cosman D. (Eur. J. Immunol. 1996)
    827. A human tumor necrosis factor p75 receptor agonist stimulates in vitro T cell proliferation but does not produce inflammation or shock in the baboon. (PubMed id 8691130)9 Welborn M.B....Moldawer L.L. (J. Exp. Med. 1996)
    828. [Changes of humoral and cellular immunity in schizophrenia]. (PubMed id 8984518)9 Wojtanowska M. and Rybakowski J. (Psychiatr. Pol. 1996)
    829. Chromosomal assignment and genomic structure of Il15. (PubMed id 7759105)9 Anderson D.M....Morris S.W. (Genomics 1995)
    830. Modulation of postoperative immune response by enteral nutrition with a diet enriched with arginine, RNA, and omega-3 fatty acids in patients with upper gastrointestinal cancer. (PubMed id 7539633)9 Senkal M....Zumtobel V. (Eur J Surg 1995)
    831. Induction of responsiveness in superantigen-induced anergic T cells. Role of ligand density and costimulatory signals. (PubMed id 7602125)9 Heeg K. and Wagner H. (J. Immunol. 1995)
    832. Cyclosporine A reduces T lymphocyte activity and improves airway hyperresponsiveness in corticosteroid-dependent chronic severe asthma. (PubMed id 7621064)9 Fukuda T....Makino S. (amp 1995)
    833. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission. (PubMed id 7777534)9 Fujii H....Miyazaki T. (Proc. Natl. Acad. Sci. U.S.A. 1995)
    834. IL2-ricin fusion toxin is selectively cytotoxic in vitro to IL2 receptor-bearing tumor cells. (PubMed id 8608178)9 Frankel A....Willingham M. (Bioconjug. Chem. 1995)
    835. A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells. (PubMed id 7559633)9 Lai K.S.... Liu E.T. (J. Biol. Chem. 1995)
    836. The predictive value of changes in serologic and cell markers of HIV activity for subsequent clinical outcome in patients with asymptomatic HIV disease treated with zidovudine. (PubMed id 7546418)9 Jacobson M.A....Collier A.C. (AIDS 1995)
    837. Stimulus-dependent production of cytokines and pterins by peripheral blood mononuclear cells. (PubMed id 7622184)9 Henderson D.C. and Rippin J.J. (Immunol. Lett. 1995)
    838. Constitutive production of IL-2 by human carcinoma cells, expression of IL-2 receptor, and tumor cell growth. (PubMed id 7594483)9 Lin W.C....Whiteside T.L. (J. Immunol. 1995)
    839. Complement activation and release of tumour necrosis factor alpha, interleukin-2, interleukin-6 and soluble tumour necrosis factor and interleukin-2 receptors during and after cardiopulmonary bypass in children. (PubMed id 7624740)9 Saatvedt K....Mollnes T.E. (Scand. J. Clin. Lab. Invest. 1995)
    840. Effects of &quot;systemic&quot; budesonide concentrations on in vitro allergen-induced activation of blood mononuclear cells isolated from asthmatic patients. (PubMed id 7573828)9 Oddera S....Rossi G.A. (Allergy 1995)
    841. Evaluation by histology, immunohistology and PCR of protocollized renal biopsies 1 week post-transplant in relation to subsequent rejection episodes. (PubMed id 7566615)9 Kooijmans-Coutinho M.F....van der Woude F.J. (Nephrol. Dial. Transplant. 1995)
    842. Plasma-soluble interleukin-2 and transferrin receptor in schizophrenia and major depression. (PubMed id 7772617)9 Maes M....Bosmans E. (Eur Arch Psychiatry Clin Neurosci 1995)
    843. Thalidomide increases the synthesis of IL-2 in cultures of human mononuclear cells stimulated with Concanavalin-A, Staphylococcal enterotoxin A, and purified protein derivative. (PubMed id 8655287)9 Shannon E.J. and Sandoval F. (Immunopharmacology 1995)
    844. Cytokine production and lymphocyte subpopulations in aged humans. An assessment during nocturnal sleep. (PubMed id 8788239)9 Born J....Fehm H.L. (Mech. Ageing Dev. 1995)
    845. [Determination of cytokines and cytokine receptors in premature labor]. (PubMed id 7498714)9 Hampl M....Gallati H. (Geburtshilfe Frauenheilkd 1995)
    846. Increased cAMP and cAMP-dependent protein kinase activity mediate anti-CD2 induced suppression of anti-CD3-driven interleukin-2 production and CD25 expression. (PubMed id 8866788)9 Lin J....Bromberg J.S. (Pathobiology 1995)
    847. Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. (PubMed id 7535338)9 Musso T.... McVicar D.W. (J. Exp. Med. 1995)
    848. Cytokine interactions in human immunodeficiency virus-infected individuals: roles of interleukin (IL)-2, IL-12, and IL-15. (PubMed id 7561680)9 Seder R.A....McDyer J.F. (J. Exp. Med. 1995)
    849. Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. (PubMed id 7759480)9 Xu X....Chong A.S. (J. Biol. Chem. 1995)
    850. Characterization of B-cell lines established from two X-linked severe combined immunodeficiency patients: interleukin-15 binds to the B cells but is not internalized efficiently. (PubMed id 7632950)9 Kumaki S....Cosman D. (Blood 1995)
    851. Immunological alterations induced by adjuvant treatment of postoperative colon carcinoma Duke's B or C with levamisole in combination with 5-FU. (PubMed id 8572636)9 De Brabander M....Vogels O. (Anticancer Res. 1995)
    852. Primary cutaneous CD30(Ki-1)-positive lymphoma of non-T, non-B origin. (PubMed id 7599389)9 Akiyama C....Tamaki K. (Dermatology (Basel) 1995)
    853. Retroviral vector for gene therapy of X-linked severe combined immunodeficiency syndrome. (PubMed id 7633846)9 Qazilbash M.H....Liu J.M. (J Hematother 1995)
    854. Cytokine gene expression after allogeneic bone marrow transplantation. (PubMed id 7787751)9 Tanaka J....Miyazaki T. (amp 1995)
    855. Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis. (PubMed id 7500023)9 Jeannin P....Bonnefoy J.Y. (J. Exp. Med. 1995)
    856. Selection of monoclonal antibodies for the identification of lymphocyte surface antigens in the New World primate Saguinus oedipus oedipus (cotton top tamarin). (PubMed id 7836781)9 Wilson A.D....Morgan A.J. (J. Immunol. Methods 1995)
    857. Direct inhibition of human CD8+ lymphocyte activation by cyclosporine A and Rapamune-Sirolimus. (PubMed id 7586731)9 Combates N.J....Raska K. (Clin. Immunol. Immunopathol. 1995)
    858. Ouabain induces inhibition of the progression phase in human T-cell proliferation. (PubMed id 7593202)9 Brodie C....Gelfand E.W. (J. Cell. Physiol. 1995)
    859. Cytokine production in a whole-blood assay after Epstein-Barr virus infection in vivo. (PubMed id 7697531)9 Hornef M.W....Kirchner H. (Clin. Diagn. Lab. Immunol. 1995)
    860. Tumor-associated lymphocytes (TAL) are competent to produce higher levels of cytokines in neoplastic pleural and peritoneal effusions than those found in sera and are able to release into culture higher levels of IL-2 and IL-6 than those released by PBMC. (PubMed id 8528743)9 Mantovani G....Santona M.C. (J. Mol. Med. 1995)
    861. Serum cytokine levels correlate with clinical parameters in Hodgkin's disease. (PubMed id 7545429)9 GorschlA1ter M....Tesch H. (Ann. Oncol. 1995)
    862. Pentoxifylline exerts synergistic immunomodulatory effects in combination with dexamethasone or cyclosporin A. (PubMed id 8964650)9 Funk J.O....Zabel P. (Int. J. Immunopharmacol. 1995)
    863. Clinical implications of cytokine and soluble receptor measurements in patients with newly-diagnosed aggressive non-Hodgkin's lymphoma. (PubMed id 7859883)9 Stasi R....Cantonetti M. (Eur. J. Haematol. 1995)
    864. Molecular analysis of Ras activation by tyrosine phosphorylated Vav. (PubMed id 8554611)9 Gulbins E....Coggeshall K.M. (Biochem. Biophys. Res. Commun. 1995)
    865. delta 9-Tetrahydrocannabinol (THC) causes the variable expression of IL2 receptor subunits. (PubMed id 7636714)9 Zhu W....Klein T.W. (J. Pharmacol. Exp. Ther. 1995)
    866. Phase I trial of escalating doses of interleukin-1 beta in combination with a fixed dose of interleukin-2. (PubMed id 7844609)9 Triozzi P.L....Villasmil P.M. (J. Clin. Oncol. 1995)
    867. Cytokines and adhesion molecules in respiratory allergy. (PubMed id 7626191)9 Palma-Carlos A.G....Melo A. (Allerg Immunol (Paris) 1995)
    868. Role of peripheral CD8 lymphocytes and soluble IL-2 receptor in predicting the duration of corticosteroid treatment in polymyalgia rheumatica and giant cell arteritis. (PubMed id 7677440)9 Salvarani C....Portioli I. (Ann. Rheum. Dis. 1995)
    869. Angiocentric immunoproliferative lesions of the skin show lobular panniculitis and are mainly disorders of large granular lymphocytes. (PubMed id 8522304)9 Takeshita M....Uike N. (Hum. Pathol. 1995)
    870. Serum cytokines in juvenile rheumatoid arthritis. Correlation with conventional inflammation parameters and clinical subtypes. (PubMed id 7848311)9 Mangge H....Schauenstein K. (Arthritis Rheum. 1995)
    871. [Cytokine mediators in acute inflammation and chronic course of viral hepatitis]. (PubMed id 7727201)9 Missale G....Fiaccadori F. (Ann. Ital. Med. Int. 1995)
    872. HLA-DR expression on CD8 lymphocytes from gastric mucosa in urease-positive and urease-negative gastritis. (PubMed id 7773247)9 Ihan A....Gubina M. (FEMS Immunol. Med. Microbiol. 1995)
    873. Interleukin-10 downregulates proliferation and expression of interleukin-2 receptor p55 chain and interferon-gamma, but not interleukin-2 or interleukin-4, by parasite-specific helper T cell clones obtained from cattle chronically infected with Babesia bovis or Fasciola hepatica. (PubMed id 8564714)9 Chitko-McKown C.G....Brown W.C. (amp 1995)
    874. T cell reconstitution by haploidentical BMT does not restore the diversification of the Ig heavy chain gene in patients with X-linked SCID. (PubMed id 8750273)9 Minegishi Y....Yata J. (Bone Marrow Transplant. 1995)
    875. Diarrhoea in HIV-infected patients: no evidence of cytokine-mediated inflammation in jejunal mucosa. (PubMed id 7794541)9 Snijders F....Reiss P. (AIDS 1995)
    876. Qualitative and quantitative analysis of T lymphocytes during normal human pregnancy. (PubMed id 7576120)9 Sabahi F....Frenkel L.D. (Am. J. Reprod. Immunol. 1995)
    877. Arterial and venous cytokine response to cardiopulmonary bypass for low risk CABG and relation to hemodynamics. (PubMed id 7727142)9 Deng M.C....Scheld H.H. (Eur J Cardiothorac Surg 1995)
    878. Lack of proliferative response by gluten-specific T cells in the blood and gut of patients with dermatitis herpetiformis. (PubMed id 7492350)9 Baker B.S....Fry L. (J. Autoimmun. 1995)
    879. Simultaneous three-color analysis of the surface phenotype and DNA-RNA quantitation using 7-amino-actinomycin D and pyronin Y. (PubMed id 7540639)9 Toba K....Shibata A. (J. Immunol. Methods 1995)
    880. Cloning and expression of the gene coding for IL-2(60)-PE40, a molecular targeted protein. (PubMed id 8580481)9 Zhang M....Lu S. (Chin. Med. Sci. J. 1995)
    881. Inhibition of endotoxin-induced cytokine release and neutrophil activation in humans by use of recombinant bactericidal/permeability-increasing protein. (PubMed id 7797904)9 von der MAPhlen M.A....Bauer R. (J. Infect. Dis. 1995)
    882. [Eosinophil colony stimulating factor (Eo-CSF) activity and soluble interleukin-2 receptor (sIL-2R) in patients with reactive eosinophilia]. (PubMed id 8857112)9 Watanabe K....Furusawa S. (Arerugi 1995)
    883. Oligoclonal activation of CD4+ T lymphocytes in posterior uveitis. (PubMed id 7882564)9 Feron E.J....Lightman S.L. (Clin. Exp. Immunol. 1995)
    884. Transplantation-related complications predicted by cytokine gene expression in the mixed lymphocyte culture in allogeneic bone marrow transplants. (PubMed id 8574169)9 Tanaka J....Sakurada K. (amp 1995)
    885. Acute renal and immunological effects of low-dose cyclosporin in humans. (PubMed id 8559498)9 De Nicola L....Conte G. (Nephrol. Dial. Transplant. 1995)
    886. p75 and Trk: a two-receptor system. (PubMed id 7571013)9 Chao M.V. and Hempstead B.L. (Trends Neurosci. 1995)
    887. IL-2 signaling involves recruitment and activation of multiple protein tyrosine kinases by the IL-2 receptor. (PubMed id 7486666)9 Taniguchi T....Liu Z.J. (Ann. N. Y. Acad. Sci. 1995)
    888. Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex. (PubMed id 7718508)9 Kimura Y....Sugamura K. (Int. Immunol. 1995)
    889. Prognostic value of serum IL-10 and soluble IL-2 receptor levels in aggressive non-Hodgkin's lymphoma. (PubMed id 7819101)9 Stasi R....Tura S. (Br. J. Haematol. 1994)
    890. PHA induces IL-2 receptors on B-CLL cells and is a potential biological response modifier for the LIL-2-diphtheria toxin, DAB486IL-2. (PubMed id 8107488)9 Bulger K....McCaffrey R. (Leuk. Res. 1994)
    891. The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c. (PubMed id 8070818)9 Leonard W.J....McBride O.W. (Immunol. Rev. 1994)
    892. Severe combined immunodeficiency, interleukin-2 (IL-2), and the IL-2 receptor: experiments of nature continue to point the way. (PubMed id 8298124)9 Voss S.D....Sondel P.M. (Blood 1994)
    893. Costimulation of cutaneous T-cell lymphoma cells by interleukin-7 and interleukin-2: potential autocrine or paracrine effectors in the SAczary syndrome. (PubMed id 8113839)9 Foss F.M....Sausville E.A. (J. Clin. Oncol. 1994)
    894. Angiocentric lymphoma with granulomatous panniculitis in the skin expressing natural killer cell and large granular T-cell phenotypes. (PubMed id 7850074)9 Takeshita M....Goto H. (Virchows Arch. 1994)
    895. SH2-dependent association of phosphatidylinositol 3'-kinase 85-kDa regulatory subunit with the interleukin-2 receptor beta chain. (PubMed id 7509794)9 Truitt K.E....Imboden J.B. (J. Biol. Chem. 1994)
    896. An anti-IL-2 antibody increases serum half-life and improves anti-tumor efficacy of human recombinant interleukin-2. (PubMed id 7852053)9 Courtney L.P....Karavodin L.M. (Immunopharmacology 1994)
    897. [Cytokine and disease]. (PubMed id 7523745)9 Tsudo M. (Rinsho Byori 1994)
    898. Production of soluble ICAM-1 by mononuclear cells from patients with rheumatoid arthritis patients. (PubMed id 7911453)9 Shingu M....Naono T. (Inflammation 1994)
    899. Effect of high-dose steroid therapy on T-cell subpopulations. A longitudinal study in MS patients. (PubMed id 8191883)9 Gallo P....Tavolato B. (Acta Neurol. Scand. 1994)
    900. [Cytokines and vasculitis]. (PubMed id 7933578)9 Shingu M. and Nobunaga M. (Nippon Rinsho 1994)
    901. The interplay of interleukin-10 (IL-10) and interleukin-2 (IL-2) in humoral immune responses: IL-10 synergizes with IL-2 to enhance responses of human B lymphocytes in a mechanism which is different from upregulation of CD25 expression. (PubMed id 8069928)9 Itoh K....Hirohata S. (Cell. Immunol. 1994)
    902. Detection of soluble interleukin-2 receptor and interleukin-10 in the serum of patients with aggressive non-Hodgkin's lymphoma. Identification of a subset at high risk of treatment failure. (PubMed id 8082082)9 Stasi R....Papa G. (Cancer 1994)
    903. Comparison of salmeterol with placebo in mild asthma: effect on peripheral blood phagocyte function and cytokine levels. (PubMed id 7920018)9 Ramage L....Dhillon D.P. (Int. Arch. Allergy Immunol. 1994)
    904. Primary activation of V gamma 9-expressing gamma delta T cells by Mycobacterium tuberculosis. Requirement for Th1-type CD4 T cell help and inhibition by IL-10. (PubMed id 7909828)9 Pechhold K....Kabelitz D. (J. Immunol. 1994)
    905. A similar expression pattern of adhesion molecules between intermediate TCR cells in the liver and intraepithelial lymphocytes in the intestine. (PubMed id 7799843)9 Ohtsuka K....Abo T. (Microbiol. Immunol. 1994)
    906. The effect of azathioprine on serum levels of interleukin 6 and soluble interleukin 2 receptor. (PubMed id 8165444)9 Crilly A....Madhok R. (Scand. J. Rheumatol. 1994)
    907. Comparative mapping of canine and human proximal Xq and genetic analysis of canine X-linked severe combined immunodeficiency. (PubMed id 7829103)9 DeschA-nes S.M....Henthorn P.S. (Genomics 1994)
    908. Transforming growth factor-beta inhibits IL-4 and IFN-gamma production by stimulated human T cells. (PubMed id 8186198)9 Holter W....Knapp W. (Int. Immunol. 1994)
    909. SjAPgren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium. (PubMed id 8056525)9 Jones D.T....Pflugfelder S.C. (amp 1994)
    910. Adoptive immunotherapy with activated peripheral blood lymphocytes. (PubMed id 8152278)9 Horvath J. and Sinkovics J.G. (Leukemia 1994)
    911. Glycosyl phosphatidylinositol membrane anchor is not required for T cell activation through CD73. (PubMed id 8027539)9 Resta R....Thompson L.F. (J. Immunol. 1994)
    912. Transduction of the IL2 gene into human acute leukemia cells: induction of tumor rejection without modifying cell proliferation and IL2 receptor expression. (PubMed id 8169977)9 Cignetti A....Foa R. (J. Natl. Cancer Inst. 1994)
    913. Differential expression and regulation of cytokine mRNAs in normal human CD45R T cell subsets. (PubMed id 7518260)9 Beckman I....Bradley J. (Cytokine 1994)
    914. Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis. (PubMed id 8077727)9 Aurelius E....StrannegAYrd O. (J. Infect. Dis. 1994)
    915. Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes. (PubMed id 7957562)9 Joyce D.A....Brennan F.M. (Eur. J. Immunol. 1994)
    916. Relationship of IgG glycosylation, soluble IL-2 receptors and IL-6 to disease activity in rheumatoid arthritis. (PubMed id 7921769)9 Bond A....Hay F.C. (Br. J. Rheumatol. 1994)
    917. Circulating levels of cytokines and soluble cytokine receptors in various T-cell malignancies. (PubMed id 8168046)9 Raziuddin S....al-Janadi M. (Cancer 1994)
    918. Phenotypic and functional abnormalities in the peripheral blood T-cells of patients with primary Sjogren's syndrome. (PubMed id 8082485)9 Aziz K.E....Wakefield D. (Cytometry 1994)
    919. Cytokine gene expression in aortic adventitial inflammation associated with advanced atherosclerosis (chronic periaortitis). (PubMed id 7962625)9 Ramshaw A.L....Parums D.V. (J. Clin. Pathol. 1994)
    920. Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression. (PubMed id 8148443)9 Patarca R....Fletcher M.A. (Clin. Infect. Dis. 1994)
    921. p56lck phosphorylation by Ca2+/calmodulin-dependent protein kinase type II. (PubMed id 8292050)9 Bland M.M....Carrera A.C. (Biochem. Biophys. Res. Commun. 1994)
    922. Cytokine levels in serum and synovial fluid of patients with juvenile rheumatoid arthritis. (PubMed id 7699643)9 Madson K.L....Osborn T.G. (J. Rheumatol. 1994)
    923. Activation via TCR or IL-2 receptor of a CD8+ suppressor T cell clone: effect on IL-10 production and on proliferation of the suppressor T cell. (PubMed id 7765241)9 Minai Y....Kaminogawa S. (Cytotechnology 1994)
    924. Expression of alpha-fetoprotein and interleukin 2 receptors and impairment of membrane fluidity in peripheral blood mononuclear cells from AIDS and related syndromes. (PubMed id 7529036)9 Macho A....Uriel J. (AIDS Res. Hum. Retroviruses 1994)
    925. Coiled-coil molecular recognition: directed solution assembly of receptor ectodomains. (PubMed id 7831285)9 Wu Z....Ciardelli T.L. (Protein Eng. 1994)
    926. Differences in IL-2 receptor levels between mycosis fungoides and cutaneous type adult T-cell leukemia/lymphoma in the early stages of the disease. (PubMed id 8176252)9 Oishi M....Honda M. (J. Invest. Dermatol. 1994)
    927. Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions. (PubMed id 7519240)9 Clement M.V. and Stamenkovic I. (J. Exp. Med. 1994)
    928. Immunomodulatory effects of three macrolides, midecamycin acetate, josamycin, and clarithromycin, on human T-lymphocyte function in vitro. (PubMed id 7532933)9 Morikawa K....Iwamoto K. (Antimicrob. Agents Chemother. 1994)
    929. T lymphocytes bearing the gamma/delta T-cell receptor in cutaneous lesions of dermatitis herpetiformis. (PubMed id 7868753)9 Kell D.L....Smoller B.R. (J. Cutan. Pathol. 1994)
    930. Peripheral blood hairy cell leukemia cells express only low affinity IL-2 receptors. (PubMed id 8107487)9 Bulger K....McCaffrey R. (Leuk. Res. 1994)
    931. Response of soluble IL-2 receptor levels during gold therapy for rheumatoid arthritis. (PubMed id 8039284)9 Sheldon A....Roberts-Thomson P.J. (Clin. Exp. Rheumatol. 1994)
    932. Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood. (PubMed id 7981154)9 Ishii N....Sugamura K. (Int. Immunol. 1994)
    933. [The effect of interleukin-2, interleukin-4 and tumor necrosis factor on LAK cells activity]. (PubMed id 7922766)9 Zeng Z....Yu M. (Zhonghua Yi Xue Za Zhi 1994)
    934. CD3- and CD28-activating pathways in HCV infection. (PubMed id 7986335)9 Corado J.A....Machado I.V. (Viral Immunol. 1994)
    935. Complement activation in dialysis: effects on cytokines, lymphocyte activation and beta 2 microglobulin. (PubMed id 7806419)9 Gardinali M....Zoni U. (Int J Artif Organs 1994)
    936. Tissue-specific regulation of IL-4 mRNA expression in human tonsil. (PubMed id 7507959)9 Secrist H....Peters M.G. (J. Immunol. 1994)
    937. Activation of cord T lymphocytes. IV. Analysis of surface expression and functional role of 1F7 (CD26) molecule. (PubMed id 7909498)9 Gerli R....Bertotto A. (Cell. Immunol. 1994)
    938. Delta-9-tetrahydrocannabinol treatment results in a suppression of interleukin-2-induced cellular activities in human and murine lymphocytes. (PubMed id 7523319)9 Trisler K. and Specter S. (Int. J. Immunopharmacol. 1994)
    939. Glucocorticoid-mediated inhibition of interleukin-2 receptor alpha and -beta subunit expression by human T cells. (PubMed id 8206753)9 Batuman O.A....Pomerantz R.J. (Immunopharmacology 1994)
    940. Rapid exacerbation of scleroderma in a patient treated with interleukin 2 and lymphokine activated killer cells for renal cell carcinoma. (PubMed id 8035405)9 Puett D.W. and Fuchs H.A. (J. Rheumatol. 1994)
    941. In vivo cytokine production and recombinant interleukin 2 immunotherapy: an insight into the possible mechanisms underlying clinical responses. (PubMed id 8198981)9 Deehan D.J....Eremin O. (Br. J. Cancer 1994)
    942. IL-2R gamma gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease. (PubMed id 7829104)9 Henthorn P.S....Felsburg P.J. (Genomics 1994)
    943. Long-term inositol phosphate release, but not tyrosine kinase activity, correlates with IL-2 secretion and NF-AT induction in anti-CD3-activated peripheral human T lymphocytes. (PubMed id 8039243)9 Bryan R.G....Rich R.R. (Cell. Immunol. 1994)
    944. Enhancement of reactive oxygen species production and cell surface markers expression due to haemodialysis. (PubMed id 8084452)9 Cristol J.P....Mion C. (Nephrol. Dial. Transplant. 1994)
    945. Effective induction of human NK cells with OK-432 and further augmentation of their cytolytic function by rIL-2. (PubMed id 7521509)9 Hu Z.L....Katsuki T. (Microbiol. Immunol. 1994)
    946. Peripheral blood reduction of memory (CD29+, CD45RO+, and &quot;bright&quot; CD2+ and LFA-1+) T lymphocytes in Papillon-LefA"vre syndrome. (PubMed id 7532641)9 GA^ngora R....Arnaiz-Villena A. (Hum. Immunol. 1994)
    947. [Functional roles of LFA-1 involved in signal transduction for thymocyte activation]. (PubMed id 7879572)9 Lu L.S. and Chen W.F. (Shi Yan Sheng Wu Xue Bao 1994)
    948. Genistein, a tyrosine kinase inhibitor, decreased the affinity of p56lck to beta-chain of interleukin-2 receptor in human natural killer (NK)-rich cells and decreased NK-mediated cytotoxicity. (PubMed id 7938054)9 Nishio K....Saijo N. (Proc. Soc. Exp. Biol. Med. 1994)
    949. The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. (PubMed id 8152289)9 Williamson P....Gaulton G. (Leukemia 1994)
    950. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. (PubMed id 8197161)9 Bamford R.N....Waldmann T.A. (Proc. Natl. Acad. Sci. U.S.A. 1994)
    951. Study of IL-2 receptor expression after chemoimmunotherapy in patients treated for metastatic malignant melanoma. (PubMed id 8082289)9 Mouawad R....Soubrane C. (Clin. Exp. Immunol. 1994)
    952. Immunologic parameters in systemic sclerosis. (PubMed id 8112935)9 Bruns M....Haustein U.F. (Int. J. Dermatol. 1994)
    953. The effects of the dialysis membrane on cytokine release. (PubMed id 8011981)9 Zaoui P. and Hakim R.M. (J. Am. Soc. Nephrol. 1994)
    954. Maternal and umbilical cord serum interleukin levels in preterm labor with clinical chorioamnionitis. (PubMed id 8178864)9 Lencki S.G....Eglinton G.S. (Am. J. Obstet. Gynecol. 1994)
    955. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. (PubMed id 7523571)9 Carson W.E....Caligiuri M.A. (J. Exp. Med. 1994)
    956. Solitary plasmacytoma of bone and extramedullary plasmacytoma: two different nosological entities? (PubMed id 7839469)9 Guida M....De Lena M. (Tumori 1994)
    957. Lymphokine receptors: a target for immunotherapy of lymphomas. (PubMed id 8172810)9 Waldmann T.A. (Ann. Oncol. 1994)
    958. A study of interactions among markers of macrophage functions in metastatic solid tumors: neopterin levels in relation to those of tumor necrosis factor-alpha and of soluble interleukin-2 receptors. (PubMed id 7976492)9 Lissoni P....Angelini A. (J. Biol. Regul. Homeost. Agents 1994)
    959. Study of peripheral blood lymphocyte subset distribution and IL-2 receptor (IL-2 R) p55-p75 subunit expression in patients with cancer of different sites. (PubMed id 7736535)9 Mantovani G....Del Giacco G.S. (Cell Biophys. 1994)
    960. [Immunologic parameters in women with normal pregnancy and pre-eclampsia]. (PubMed id 8023619)9 Bettin S....Jahn S. (Zentralbl Gynakol 1994)
    961. Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine. (PubMed id 7923243)9 Berd D....Murphy G. (Cancer Immunol. Immunother. 1994)
    962. Expression of the IL2 receptor alpha, beta and gamma chains in hairy cell leukemia. (PubMed id 7820050)9 de Totero D....Foa R. (amp 1994)
    963. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. (PubMed id 8178155)9 Grabstein K.H.... Giri J.G. (Science 1994)
    964. Does IL-2 receptor expression and secretion in chronic B-cell leukemia have a role in down-regulation of the immune system? (PubMed id 8289505)9 Burton J. and Kay N.E. (Leukemia 1994)
    965. Follow up of soluble IL-2 receptor level in metastatic malignant melanoma patients treated by chemoimmunotherapy. (PubMed id 8306497)9 Soubrane C....Khayat D. (Clin. Exp. Immunol. 1994)
    966. Preferential utilization of the immature JH segment and absence of somatic mutation in the CDR3 junction of the Ig H chain gene in three X-linked severe combined immunodeficiency patients. (PubMed id 7865464)9 Minegishi Y....Yata J. (Int. Immunol. 1994)
    967. Systemic cytokine measurements: their role in monitoring the response to therapy in patients with rheumatoid arthritis. (PubMed id 7842530)9 Luqmani R....Emery P. (Clin. Exp. Rheumatol. 1994)
    968. Synthesis of interleukin-5 by activated eosinophils in patients with eosinophilic heart diseases. (PubMed id 8364205)9 Desreumaux P....Prin L. (Blood 1993)
    969. Interleukin-4 bypass of the immunosuppressive effect mediated by interleukin-2 receptor antibodies. (PubMed id 8434232)9 Steinmann J....MA1ller-Ruchholtz W. (Scand. J. Immunol. 1993)
    970. Restricted cytokine expression in rheumatoid arthritis. (PubMed id 8318038)9 Chen E....Fish E.N. (Arthritis Rheum. 1993)
    971. Expression of IL-2 receptors in human melanoma cells. (PubMed id 8317884)9 Rimoldi D....Carrel S. (Anticancer Res. 1993)
    972. Interaction of IL-1 beta, IL-6 and tumour necrosis factor-alpha (TNF-alpha) in human T cells activated by murine antigens. (PubMed id 8370177)9 Panzer S....Matsuki K. (Clin. Exp. Immunol. 1993)
    973. Increase of interleukin 2 receptor and CD45RO antigen on lymphocytes cultured with human cytomegalovirus. (PubMed id 8384933)9 Nakano T....Sakurai M. (Cell. Immunol. 1993)
    974. In vitro modulatory effects of interleukin-3 on macrophage activation induced by interleukin-2. (PubMed id 8443757)9 Lissoni P....Biondi A. (Cancer 1993)
    975. High frequency of spontaneous interferon-gamma-producing cells in human tonsils: role of local accessory cells and soluble factors. (PubMed id 8093434)9 Quiding M....Czerkinsky C. (Clin. Exp. Immunol. 1993)
    976. Pivotal role of endogenous TNF-alpha in the IL-2-driven activation and proliferation of the functionally immature NK free subset. (PubMed id 8402935)9 Jewett A. and Bonavida B. (Cell. Immunol. 1993)
    977. Relationship between IL-2 receptor expression and proliferative responses in lymphocytes from HIV-1 seropositive homosexual men. (PubMed id 8093435)9 Chopra R.K....Margolick J.B. (Clin. Exp. Immunol. 1993)
    978. Tumour-infiltrating lymphocytes in primary melanoma: functional consequences of differential IL-2 receptor expression. (PubMed id 7678210)9 Becker J.C....BrAPcker E.B. (Clin. Exp. Immunol. 1993)
    979. Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle. (PubMed id 8419408)9 Terada N....Gelfand E.W. (J. Cell. Physiol. 1993)
    980. Increased soluble IL-2 receptor in serum of patients with systemic lupus erythematosus. (PubMed id 8358979)9 Sawada S....Mitamura K. (Clin. Rheumatol. 1993)
    981. [Effect of arginine supplementation on T-lymphocyte function in burn patients]. (PubMed id 8143212)9 Lu S.L. (Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 1993)
    982. Circulating intercellular adhesion molecule-1 in patients with systemic sclerosis. (PubMed id 8099861)9 Sfikakis P.P....Tsokos G.C. (Clin. Immunol. Immunopathol. 1993)
    983. Modulation of human T cell responses by nitric oxide and its derivative, S-nitrosoglutathione. (PubMed id 8216401)9 Merryman P.F....Abramson S.B. (Arthritis Rheum. 1993)
    984. Relationship of IL-2, IL-2R (CD25+), soluble IL-2R and IL-4 with disease activity in SLE patients. (PubMed id 8268974)9 Cuadrado M.J....Santamaria M. (Lupus 1993)
    985. Interleukin 2 protects hairy leukemic cells from lymphokine-activated killer cell-mediated cytotoxicity. (PubMed id 7687924)9 Reiter Z. and Taylor M.W. (Cancer Res. 1993)
    986. Mitogenic signal transduction in T lymphocytes in microgravity. (PubMed id 8501396)9 Cogoli A....MA1ller O. (J. Leukoc. Biol. 1993)
    987. Down-regulation of cytokine production and interleukin-2 receptor expression by pooled human IgG. (PubMed id 8344700)9 Andersson U.G....Andersson J.P. (Immunology 1993)
    988. DAB486IL-2 fusion toxin in refractory rheumatoid arthritis. (PubMed id 8216416)9 Sewell K.L....Trentham D.E. (Arthritis Rheum. 1993)
    989. Correlation of interleukin-2 and soluble interleukin-2 receptor with clinical activity of multiple sclerosis. (PubMed id 8437006)9 Sharief M.K. and Thompson E.J. (J. Neurol. Neurosurg. Psychiatr. 1993)
    990. Bidirectional modulation of human B cell stimulation by activated T cells. (PubMed id 8370072)9 Hirohata S. and Shinohara S. (Cell. Immunol. 1993)
    991. 1992 Stohlman Memorial Lecture: targeting the IL-2 receptor. (PubMed id 8361223)9 Waldmann T.A. (Leukemia 1993)
    992. In vitro lymphocyte reactivity to heavy metal salts in the diagnosis of oral mucosal hypersensitivity to amalgam restorations. (PubMed id 8427819)9 Nordlind K. and Liden S. (Br. J. Dermatol. 1993)
    993. Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. (PubMed id 8228801)9 Fluckiger A.C....Banchereau J. (J. Exp. Med. 1993)
    994. Evidence for local and systemic activation of immune cells by peritumoral injections of interleukin 2 in patients with advanced squamous cell carcinoma of the head and neck. (PubMed id 8242620)9 Whiteside T.L....Herberman R.B. (Cancer Res. 1993)
    995. Insulin-dependent diabetes in the NOD mouse model. II. Beta cell destruction in autoimmune diabetes is a TH2 and not a TH1 mediated event. (PubMed id 8105989)9 Anderson J.T....Peck A.B. (Autoimmunity 1993)
    996. Leflunomide, a novel immunosuppressive agent. The mechanism of inhibition of T cell proliferation. (PubMed id 8390735)9 Chong A.S....Williams J.W. (Transplantation 1993)
    997. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. (PubMed id 8266077)9 Noguchi M....Leonard W.J. (Science 1993)
    998. Inhibition of human T cell response to staphylococcal enterotoxin B by prior ligation of surface CD4 molecules. (PubMed id 8102087)9 Fournel S....Bonnefoy-Berard N. (Cell. Immunol. 1993)
    999. Contribution of serum inhibitory factors and immune cellular defects to the depressed cell-mediated immunity in patients with head and neck cancer. (PubMed id 8214299)9 Wanebo H.J....Mehta S. (Am. J. Surg. 1993)
    1000. The in vitro senescence of human T lymphocytes: failure to divide is not associated with a loss of cytolytic activity or memory T cell phenotype. (PubMed id 8469029)9 Perillo N.L....Effros R.B. (Mech. Ageing Dev. 1993)
    1001. Tumour growth inhibition in mice by glycosylated recombinant human lymphotoxin: analysis of tumour-regional mononuclear cells involved with its action. (PubMed id 8439496)9 Funahashi I....Miyaji H. (Br. J. Cancer 1993)
    1002. Experimental modulation of IL-1 production and cell surface molecule expression by levamisole. (PubMed id 8103313)9 Kimball E.S. (Ann. N. Y. Acad. Sci. 1993)
    1003. Atopic dermatitis: correlation of peripheral blood T cell activation, eosinophilia and serum factors with clinical severity. (PubMed id 8448682)9 Walker C....WA1thrich B. (Clin. Exp. Allergy 1993)
    1004. Prevention of cyclophosphamide-induced diabetes in the NOD/WEHI mouse with deoxyspergualin. (PubMed id 8428390)9 Nicoletti F....Magro G. (Clin. Exp. Immunol. 1993)
    1005. Glycyrrhizin as a promoter of the late signal transduction for interleukin-2 production by splenic lymphocytes. (PubMed id 8406577)9 Zhang Y.H....Nakashima I. (Immunology 1993)
    1006. Coronary sinus sampling of cytokines after heart transplantation: evidence for macrophage activation and interleukin-4 production within the graft. (PubMed id 8417059)9 Fyfe A....Cardella C. (J. Am. Coll. Cardiol. 1993)
    1007. The relevance of antimalarial therapy with regard to thrombosis, hypercholesterolemia and cytokines in SLE. (PubMed id 8485565)9 Wallace D.J....Stecher V.J. (Lupus 1993)
    1008. Exogenous glutamine requirement is confined to late events of T cell activation. (PubMed id 7905486)9 HAPrig H....Heberer M. (J. Cell. Biochem. 1993)
    1009. The synergistic effects of interleukin 2 and interleukin 7 on the proliferation and autologous tumor cell lysis of tumor-associated lymphocytes. (PubMed id 8292458)9 Tsukuda M....Yanoma S. (Biotherapy 1993)
    1010. Signalling via the TCR/CD3 antigen receptor complex in uremia is limited by the receptors number. (PubMed id 8101978)9 Stachowski J....Baldamus C.A. (Nephron 1993)
    1011. Elevation of soluble IL-2 receptor and IL-4, and nonelevation of IFN-gamma in sera from patients with allergic asthma. (PubMed id 8250351)9 Hashimoto S....Horie T. (Ann Allergy 1993)
    1012. Interleukin-2, soluble interleukin-2-receptor, neopterin, L-tryptophan and beta 2-microglobulin levels in CSF and serum of patients with relapsing-remitting or chronic-progressive multiple sclerosis. (PubMed id 8138825)9 Ott M....Fischer P.A. (J. Neurol. 1993)
    1013. Modulation of biological responses of normal human mononuclear cells by antiestrogens. (PubMed id 8476225)9 Teodorczyk-Injeyan J....Kellen J.A. (Anticancer Res. 1993)
    1014. Normal and aberrant expression of cytokines in neoplastic cells from chronic lymphocytic leukemias. (PubMed id 8393431)9 Plate J.M....Gregory S.A. (Hum. Immunol. 1993)
    1015. The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation. (PubMed id 8384218)9 Merida I....Gaulton G.N. (J. Biol. Chem. 1993)
    1016. Interferon-gamma, interleukin (IL)-2 and IL-2 receptor expressions in hepatitis C virus-infected liver. (PubMed id 8395442)9 Morshed S.A....Nishioka M. (Gastroenterol. Jpn. 1993)
    1017. Retinal antigen specific lymphocytes, TCR-gamma delta T cells and CD5+ B cells cultured from the vitreous in acute sympathetic ophthalmitis. (PubMed id 7511004)9 Liversidge J....Forrester J.V. (Autoimmunity 1993)
    1018. The role of cytokines in the pathophysiology of chronic liver diseases. (PubMed id 8123873)9 Tilg H. (amp 1993)
    1019. Expression of human IL-2 receptor alpha- and beta-chains using the baculovirus expression system. (PubMed id 8356402)9 Lindqvist C....Oker-Blom C. (Scand. J. Immunol. 1993)
    1020. [Ultradian variations of interleukin-1 beta concentration (IL-1 beta), interferon gamma (IFN-gamma) and soluble IL-2 receptors (RIL-2) in healthy volunteers humen]. (PubMed id 8019924)9 Bouayad-Amine D....Serrou B. (C. R. Seances Soc. Biol. Fil. 1993)
    1021. Study of T-cell activation in type I diabetic patients and pre-type I diabetic subjects by cytometric analysis: antigen expression defect in vitro. (PubMed id 8095271)9 Giordano C....Galluzzo A. (J. Clin. Immunol. 1993)
    1022. Pilot study of natural human interleukin-2 in patients with chronic hepatitis B. Immunomodulatory and antiviral effects. (PubMed id 8301059)9 Tilg H....Schwulera U. (J. Hepatol. 1993)
    1023. Suppression of interleukin-2 and interleukin-2 receptor biosynthesis by gold compounds in in vitro activated human peripheral blood mononuclear cells. (PubMed id 8431210)9 Sfikakis P.P....Panayiotidis P.P. (Arthritis Rheum. 1993)
    1024. Regulation of lymphocyte function by protein phosphorylation. (PubMed id 8476569)9 Perlmutter R.M....Alberola-Ila J. (Annu. Rev. Immunol. 1993)
    1025. Cytokine gene expression in skin and lymphoid organs in graft versus host disease. (PubMed id 8496391)9 Rowbottom A.W....Sloane J.P. (J. Clin. Pathol. 1993)
    1026. Interleukin-2 receptor signal transduction: translocation of active serine-threonine kinase Raf-1 from IL-2 receptor into cytosol depends on IL-2-induced tyrosine kinase activation. (PubMed id 8438242)9 Maslinski W....Strom T.B. (Transplant. Proc. 1993)
    1027. Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers. (PubMed id 8358720)9 LeMaistre C.F....Woodworth T. (Cancer Res. 1993)
    1028. Suppressive mechanisms of alveolar macrophages in interstitial lung diseases: role of soluble factors and cell-to-cell contact. (PubMed id 8370444)9 Fireman E....Greif J. (Eur. Respir. J. 1993)
    1029. [Soluble interleukin 2 receptor (sIL-2R) in patients with esophageal carcinoma]. (PubMed id 8334935)9 Duan Z.F. (Zhonghua Zhong Liu Za Zhi 1993)
    1030. Inhibition of anti-CD3 monoclonal antibody-induced T-cell proliferation and interleukin-2 secretion by physiologic combinations of dexamethasone and prostaglandin E2. (PubMed id 7910781)9 Elliott L....Roszman T. (Cell. Mol. Neurobiol. 1993)
    1031. Interleukin-4 induces proliferation of adult T-cell leukemia cells. (PubMed id 8472809)9 Mori N....Eto S. (Eur. J. Haematol. 1993)
    1032. Effect of verapamil on the IL-2 binding to its active receptor and on the release of IL-2 receptor by activated PBMC. (PubMed id 8320080)9 Mikhail N....Degiannis D. (Immunopharmacology 1993)
    1033. Immunosuppressive activity of fosfomycin on human T-lymphocyte function in vitro. (PubMed id 7509146)9 Morikawa K....Sawada M. (Antimicrob. Agents Chemother. 1993)
    1034. Augmentation of lymphokine-activated killer cell activity by lentinan. (PubMed id 8267381)9 Tani M....Mizobata S. (Anticancer Res. 1993)
    1035. Signal transduction defect in the acquired immunodeficiency syndrome and AIDS-related complex. (PubMed id 8209399)9 Gupta S. (Thymus 1993)
    1036. The effects of auranofin on activation and interleukin-2 release from human peripheral blood mononuclear cells. (PubMed id 8023745)9 Vint I.A....Foreman J.C. (Agents Actions 1993)
    1037. Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer. (PubMed id 8319179)9 Baxevanis C.N....Papamichail M. (Cancer 1993)
    1038. Immunological and clinical effects of intramuscular rIFN alpha-2a and low dose subcutaneous rIL-2 in patients with advanced malignant melanoma. (PubMed id 8471836)9 Castello G....Comella G. (Melanoma Res. 1993)
    1039. The chimeric receptor between interleukin-2 receptor beta chain and interleukin-4 receptor transduces interleukin-2 signal. (PubMed id 7679903)9 Izuhara K....Harada N. (Biochem. Biophys. Res. Commun. 1993)
    1040. IL-2 receptor gene expression and IL-2 production by human preterm newborns' cells. (PubMed id 8370178)9 Bessler H....Djaldetti M. (Clin. Exp. Immunol. 1993)
    1041. Regulation of PtdIns-3-kinase and the guanine nucleotide binding proteins p21ras during signal transduction by the T cell antigen receptor and the interleukin-2 receptor. (PubMed id 8260648)9 Cantrell D.A....Woodrow M. (Semin. Immunol. 1993)
    1042. Inhibition of human mononuclear cell proliferation, interleukin synthesis, mRNA for IL-2, IL-6, and leukotriene B4 synthesis by a lipoxygenase inhibitor. (PubMed id 8409748)9 Atluru D....Woloschak G.E. (J. Leukoc. Biol. 1993)
    1043. Increased interleukin-6 levels in cerebrospinal fluid following subarachnoid hemorrhage. (PubMed id 8450329)9 Mathiesen T....von Holst H. (J. Neurosurg. 1993)
    1044. Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3). (PubMed id 8340408)9 Sakamaki K....Miyajima A. (J. Biol. Chem. 1993)
    1045. Immunological effects of a single evening subcutaneous injection of low-dose interleukin-2 in association with the pineal hormone melatonin in advanced cancer patients. (PubMed id 1296454)9 Lissoni P....Maestroni G.J. (J. Biol. Regul. Homeost. Agents 1992)
    1046. IL-2 and a contact-mediated signal provided by TCR alpha beta + or TCR gamma delta + CD4+ T cells induce polyclonal Ig production by committed human B cells. Enhancement by IL-5, specific inhibition of IgA synthesis by IL-4. (PubMed id 1347306)9 van Vlasselaer P....de Vries J.E. (J. Immunol. 1992)
    1047. Modulation of human T cell functions by surface sulphydryl groups: differential effects on IL-2 production and responsiveness. (PubMed id 1563102)9 Smith S....Hall N.D. (Clin. Exp. Immunol. 1992)
    1048. The distinct effects of FK506 on the activation, proliferation, and differentiation of human B lymphocytes. (PubMed id 1281561)9 Morikawa K....Morikawa S. (Transplantation 1992)
    1049. The augmentation of lymphokine-activated killer activity following pulsing of human peripheral blood mononuclear cells with recombinant human interleukin-2. (PubMed id 1511461)9 Carter C.R....Rees R.C. (Cancer Immunol. Immunother. 1992)
    1050. Augmenting effect of sizofiran on the immunofunction of regional lymph nodes in cervical cancer. (PubMed id 1739919)9 Shimizu Y....Masubuchi K. (Cancer 1992)
    1051. Leukotriene B4 augments interleukin-2 receptor-beta (IL-2R beta) expression and IL-2R beta-mediated cytotoxic response in human peripheral blood lymphocytes. (PubMed id 1321793)9 StankovA! J....Rola-Pleszczynski M. (Immunology 1992)
    1052. Elevation of activated gamma delta T cell receptor bearing T lymphocytes in patients with autoimmune chronic liver disease. (PubMed id 1385768)9 Wen L....Vergani D. (Clin. Exp. Immunol. 1992)
    1053. [Changes in LAK cell activity in chronic viral hepatitis and treatment with autologous LAK cell transfusion]. (PubMed id 1478122)9 Si C.W....Yu M. (Zhonghua Nei Ke Za Zhi 1992)
    1054. Lung-restricted activation of the alveolar macrophage/monocyte system in pulmonary sarcoidosis. (PubMed id 1731582)9 MA1ller-Quernheim J....Ferlinz R. (Am. Rev. Respir. Dis. 1992)
    1055. An associated molecule, p64, with IL-2 receptor beta chain. Its possible involvement in the formation of the functional intermediate-affinity IL-2 receptor complex. (PubMed id 1545122)9 Takeshita T....Sugamura K. (J. Immunol. 1992)
    1056. The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. (PubMed id 1380951)9 Friccius H....Pawelec G. (Int. J. Immunopharmacol. 1992)
    1057. Induction of interleukin-2 receptor by tumor necrosis factor alpha on cultured ovarian tumor-associated lymphocytes. (PubMed id 1534515)9 Ioannides C.G....Freedman R.S. (Cancer Immunol. Immunother. 1992)
    1058. Role of cytokines in the adoptive immunotherapy of an experimental model of human head and neck cancer by human IL-2-activated natural killer cells. (PubMed id 1535088)9 Rabinowich H....Whiteside T.L. (J. Immunol. 1992)
    1059. Serum cytokine profiles in experimental human malaria. Relationship to protection and disease course after challenge. (PubMed id 1644922)9 Harpaz R....Sztein M.B. (J. Clin. Invest. 1992)
    1060. Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. (PubMed id 1472476)9 Mills G.B....Greene W.C. (Int. Immunol. 1992)
    1061. Structural requirements for the modulatory effect of 6-substituted pterins on interleukin 2 receptor binding. (PubMed id 1535794)9 Ziegler I....Boyle P.H. (Biochim. Biophys. Acta 1992)
    1062. Electron microscopic observation of killer cells induced by mixed culture of lymphocytes with autologous cancer cells and further culture with recombinant interleukin-2. (PubMed id 1489283)9 Murakami H....Kanda T. (Auris Nasus Larynx 1992)
    1063. The correlation between interleukin 2 and soluble interleukin 2 receptors to oestradiol, progesterone and testosterone levels in periovulatory follicles of in-vitro fertilization patients. (PubMed id 1430130)9 Barak V....Laufer N. (Hum. Reprod. 1992)
    1064. Interferon-gamma gene expression in human B-cell lines: induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation. (PubMed id 1322203)9 Pang Y....Young H.A. (Blood 1992)
    1065. Soluble IL-2 receptor and tumour necrosis factor-alpha in plasma of haemophilia patients infected with HIV. (PubMed id 1735193)9 Noronha I.L....Opelz G. (Clin. Exp. Immunol. 1992)
    1066. Defect in generation of LAK cell activity under oxygen-limited conditions. (PubMed id 1500092)9 Ishizaka S....Tsujii T. (Immunol. Lett. 1992)
    1067. Soluble interleukin-2 receptor serum levels in mycosis fungoides. Correlation with clinical stage. (PubMed id 1394062)9 Szeimies R.M....Kaudewitz P. (Cancer 1992)
    1068. Lymphocyte release of soluble IL-2 receptors in patients with minimal change nephropathy. (PubMed id 1582055)9 Mandreoli M....Zucchelli P. (Clin. Nephrol. 1992)
    1069. The mechanism of action of serum immunosuppressive factor in Crohn's disease: it blocks the growth of mitogen-stimulated lymphocytes in early G1 phase through an inhibition of transferrin receptor expression. (PubMed id 1343345)9 Iwao Y....Toda K. (amp 1992)
    1070. Serum eosinophil cationic protein (ECP) is a sensitive measure for disease activity in atopic dermatitis. (PubMed id 1571256)9 Czech W....Kapp A. (Br. J. Dermatol. 1992)
    1071. Impaired urinary excretion of soluble IL-2 receptors in patients with systemic lupus erythematosus and rheumatoid arthritis. (PubMed id 1301961)9 Manoussakis M.N....Moutsopoulos H.M. (Lupus 1992)
    1072. Inhibitory effect by 1,25-dihydroxyvitamin D3 on concanavalin A-stimulated proliferation of rat thymic lymphocytes. (PubMed id 1477603)9 Kojima A....Morii H. (Cell. Mol. Biol. (Noisy-le-grand) 1992)
    1073. Interleukin 2 production and interleukin 2 receptor expression by human immature leukemic T cells. (PubMed id 1405755)9 Sahraoui Y....Georgoulias V. (Leukemia 1992)
    1074. Mechanism of immunosuppressive effect of alprazolam: alprazolam suppresses T-cell proliferation by selectively inhibiting the production of IL2 but not acquisition of IL2 receptor. (PubMed id 1624223)9 Chang M.P....Norman D.C. (Int. J. Immunopharmacol. 1992)
    1075. TCR gamma/delta positive lymphocytes after allogeneic bone marrow transplantation. (PubMed id 1422478)9 Viale M....Bacigalupo A. (Bone Marrow Transplant. 1992)
    1076. [Intrathecal immune response in meningeosis neoplastica: IgG, IgM, oligoclonal bands and cytokines]. (PubMed id 1594086)9 Weller M....WiethAPlter H. (Nervenarzt 1992)
    1077. Soluble CD14 but not interleukin-6 is a new marker for clinical activity in atopic dermatitis. (PubMed id 1284103)9 WA1thrich B....Joller-Jemelka H. (Arch. Dermatol. Res. 1992)
    1078. Cytometrically detected specific binding of interleukin 2 to cells. (PubMed id 1498254)9 Bergmann C.A....Kaplan D.R. (Cytokine 1992)
    1079. Flow cytometric analysis of tumour infiltrating lymphocyte activation and tumour cell MHC class I and II expression in breast cancer patients. (PubMed id 1730139)9 Whitford P....Campbell A.M. (Cancer Lett. 1992)
    1080. The multichain interleukin-2 receptor: a target for immunotherapy. (PubMed id 1727619)9 Waldmann T.A....Junghans R.P. (Ann. Intern. Med. 1992)
    1081. T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones. (PubMed id 1549569)9 Wucherpfennig K.W....Hafler D.A. (Proc. Natl. Acad. Sci. U.S.A. 1992)
    1082. Cyclosporine in atopic dermatitis. Modulation in the expression of immunologic markers in lesional skin. (PubMed id 1479097)9 van Joost T....Prens E.P. (J. Am. Acad. Dermatol. 1992)
    1083. Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy. (PubMed id 1606722)9 Prummel M.F....Koornneef L. (Clin. Exp. Immunol. 1992)
    1084. Characterization of cytokine gene expression in CD4+ and CD8+ T cells after activation with phorbol myristate acetate and phytohaemagglutinin. (PubMed id 1356669)9 Leung J.C....Lai K.N. (Clin. Exp. Immunol. 1992)
    1085. Decreased interleukin-2 beta-chain receptor expression by interleukin-4 on LGL: influence on the IL-2 induced cytotoxicity and proliferation. (PubMed id 1596876)9 Lindqvist C....Akerman K. (Cancer Lett. 1992)
    1086. Phenotype, activation and lymphokine secretion by gamma/delta T lymphocytes from schistosomiasis and carcinoma of the urinary bladder. (PubMed id 1531634)9 Raziuddin S....Ibrahim A. (Eur. J. Immunol. 1992)
    1087. Tumor necrosis factor and soluble interleukin-2 receptor: two immunological biomarkers in female neoplasms. (PubMed id 1511722)9 Abbate I....Cramarossa A. (Eur. J. Gynaecol. Oncol. 1992)
    1088. [Large granular lymphocytic leukemia]. (PubMed id 1518140)9 Tagawa S....Kitani T. (Nippon Rinsho 1992)
    1089. Regulatory effects of interleukin-7 on renal tumor infiltrating lymphocytes. (PubMed id 1615582)9 Ditonno P....Belldegrun A. (Urol. Res. 1992)
    1090. Correlation of eosinophils, eosinophil cationic protein and soluble interleukin-2 receptor with the clinical activity of atopic dermatitis. (PubMed id 1421636)9 KAogi M.K....WA1thrich B. (Dermatology (Basel) 1992)
    1091. Cytokine inter-relationships and their association with disease activity in arthritis. (PubMed id 1304740)9 Holt I....Hopkins S.J. (Br. J. Rheumatol. 1992)
    1092. Cytokine responses to intraventricular injection of interleukin 2 into patients with leptomeningeal carcinomatosis: rapid induction of tumor necrosis factor alpha, interleukin 1 beta, interleukin 6, gamma-interferon, and soluble interleukin 2 receptor (Mr 55,000 protein). (PubMed id 1737371)9 List J....Grimm E.A. (Cancer Res. 1992)
    1093. Immune changes in HIV-1 infection: significant correlations and differences in serum markers and lymphoid phenotypic antigens. (PubMed id 1376654)9 Bass H.Z....Fahey J.L. (Clin. Immunol. Immunopathol. 1992)
    1094. Distribution of IL-2R and CD45Ro expression on CD4+ and CD8+ T-lymphocytes in the peripheral blood of patients with posterior uveitis. (PubMed id 1358556)9 Feron E.J....Lightman S.L. (Curr. Eye Res. 1992)
    1095. The strong correlation of cytotoxic T lymphocyte-specific serine protease gene transcripts with renal allograft rejection. (PubMed id 1733089)9 Lipman M.L....Strom T.B. (Transplantation 1992)
    1096. T-lymphocyte proliferation: tyrosine kinases in interleukin 2 signal transduction. (PubMed id 1457964)9 Schmandt R....Mills G.B. (Baillieres Clin. Haematol. 1992)
    1097. Lymphokines and soluble interleukin-2 receptors in juvenile chronic arthritis. Clinical and laboratory correlations. (PubMed id 1411093)9 MA1ller K....Bendtzen K. (Rheumatol. Int. 1992)
    1098. [OK-432-induced cytokines production by peripheral blood mononuclear cells]. (PubMed id 1307613)9 Ono M....Itoh C. (Rinsho Byori 1992)
    1099. Potentiation of IL-2-induced t-cell proliferation by retinoids. (PubMed id 1624219)9 Jiang X.L....Lamon E.W. (Int. J. Immunopharmacol. 1992)
    1100. Immunohistochemical analysis of synovial membranes from inflammatory and non-inflammatory arthritides: scarcity of CD5 positive B cells and IL2 receptor bearing T cells. (PubMed id 1374550)9 Smith M.D....Roberts-Thomson P.J. (Pathology 1992)
    1101. [The significance of soluble IL-2 receptors in rheumatoid arthritis with interstitial pneumonia]. (PubMed id 1575640)9 Tada S....Tanizaki K. (Arerugi 1992)
    1102. Okadaic acid enhances human T cell activation and phosphorylation of an internal substrate induced by phorbol myristate acetate. (PubMed id 1333455)9 Tada Y....Niho Y. (Immunopharmacology 1992)
    1103. Phenotypic changes induced by interleukin-2 (IL-2) and IL-3 in an immature T-lymphocytic leukemia are associated with regulated expression of IL-2 receptor beta chain and of protein tyrosine kinases LCK and LYN. (PubMed id 1379847)9 O'Connor R....Santoli D. (Blood 1992)
    1104. A VLA-4 alpha-chain specific monoclonal antibody enhances CD3-induced IL-2/IL-2 receptor-dependent T-cell proliferation. (PubMed id 1467362)9 Udagawa T. and McIntyre B.W. (Lymphokine Cytokine Res. 1992)
    1105. Cutaneous pleomorphic large cell lymphoma. (PubMed id 1424797)9 von den Driesch P....Hornstein O.P. (Cutis 1992)
    1106. Secretory IgA are elevated in both saliva and serum of patients with various types of primary glomerulonephritis. (PubMed id 1424290)9 Rostoker G....Weil B. (Clin. Exp. Immunol. 1992)
    1107. Modulation of macrophage response to interleukin-2 immunotherapy by interleukin-3 in cancer patients. (PubMed id 1292506)9 Lissoni P....Tancini G. (Biol. Chem. Hoppe-Seyler 1992)
    1108. Increased concentrations of interleukin 1 beta, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel disease. (PubMed id 1740278)9 Brynskov J....Vilien M. (Gut 1992)
    1109. Prophylactic use of the IL-2 receptor-specific monoclonal antibody LO-Tact-1 with cyclosporin A and steroids in renal transplantation. (PubMed id 14621841)9 Hiesse C....Bazin H. (Transpl. Int. 1992)
    1110. Effects of hemodialysis on activation of lymphocytes: analysis by an in vitro dialysis model. (PubMed id 1600120)9 Donati D....Raska K. (J. Am. Soc. Nephrol. 1992)
    1111. Immunologic effector cells in head and neck cancer. (PubMed id 1356393)9 Vitolo D....Whiteside T.L. (J. Natl. Cancer Inst. Monographs 1992)
    1112. Biocompatibility of high-flux membranes. (PubMed id 1399092)9 Putz D....Graf H. (Int J Artif Organs 1992)
    1113. [Analysis of tumor-infiltrating lymphocyte in primary malignant lymphoma of the central nervous system using double immunofluorescence staining method]. (PubMed id 1533133)9 Kunishio K....Nishimoto A. (No To Shinkei 1992)
    1114. Soluble interleukin-2 receptor, interleukin-6 and interleukin-1 beta in patients with Crohn's disease and ulcerative colitis: preoperative levels and postoperative changes of serum concentrations. (PubMed id 1639222)9 SchA1rmann G....Meuer S. (Digestion 1992)
    1115. Relationship of large and small CD3- CD56+ lymphocytes mediating NK-associated activities. (PubMed id 1381742)9 Ortaldo J.R....Bach F.H. (J. Leukoc. Biol. 1992)
    1116. The IL-2/IL-2 receptor system: involvement of a novel receptor subunit, gamma chain, in growth signal transduction. (PubMed id 1306308)9 Sugamura K....Nakamura M. (Tohoku J. Exp. Med. 1992)
    1117. Inhibitory effect of human syncytiotrophoblast plasma membrane vesicles on Jurkat cells activated by phorbol ester and calcium ionophore. (PubMed id 1309491)9 Thibault G....Bardos P. (Cell. Immunol. 1992)
    1118. Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. (PubMed id 1374452)9 HAPllsberg P....Hafler D.A. (J. Immunol. 1992)
    1119. Cytokine production and serum levels in systemic sclerosis. (PubMed id 1451330)9 Kantor T.V....Whiteside T.L. (Clin. Immunol. Immunopathol. 1992)
    1120. [Analysis of lymphocyte surface markers in childhood acute lymphoblastic leukemia during maintenance chemotherapy]. (PubMed id 1580639)9 Sugita K....Furukawa T. (amp 1992)
    1121. IL-6 and soluble IL-2 receptor in rheumatoid arthritis patients treated with second line drugs. (PubMed id 1356854)9 Watson J....Sturrock R. (Biochem. Soc. Trans. 1992)
    1122. Tumour necrosis factor receptor distribution in human lymphoid tissue. (PubMed id 1663076)9 Ryffel B....Gudat F. (Immunology 1991)
    1123. Cytokine levels during hemodialysis. (PubMed id 1751202)9 Vaziri N.D....Cesario T.C. (ASAIO Trans 1991)
    1124. HLA class II molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway. (PubMed id 1825060)9 Ruggiero G....Fontana S. (Eur. J. Immunol. 1991)
    1125. Growth of certain myeloid leukemic cells can be stimulated by interleukin-2. (PubMed id 1777232)9 Tanaka M. (Growth Factors 1991)
    1126. Therapeutic benefits of calcium channel blockers in cyclosporine-treated organ transplant recipients: blood pressure control and immunosuppression. (PubMed id 2039018)9 Weir M.R. (Am. J. Med. 1991)
    1127. Additive inhibition of afferent and efferent immunological responses of human peripheral blood mononuclear cells by verapamil and cyclosporine. (PubMed id 2014542)9 Weir M.R....Handwerger B.S. (Transplantation 1991)
    1128. Accumulation of CD16-CD56+ natural killer cells with high affinity interleukin 2 receptors in human early pregnancy decidua. (PubMed id 1716974)9 Nishikawa K....Sugamura K. (Int. Immunol. 1991)
    1129. Serum cytokine levels in chronic progressive multiple sclerosis: interleukin-2 levels parallel tumor necrosis factor-alpha levels. (PubMed id 2056069)9 Trotter J.L....van der Veen R.C. (J. Neuroimmunol. 1991)
    1130. Determination of interleukin 2 receptor number of Con A stimulated human lymphocytes with aging. (PubMed id 1667939)9 FA1lAPp T....Hirokawa K. (amp 1991)
    1131. In situ immunophenotype of macrophages and lymphocytes in granuloma formation of tuberculous lymphadenitis in HIV-infected and immunocompetent patients. (PubMed id 1896641)9 MA1ller H. and Takeshita M. (Res. Virol. 1991)
    1132. Cytokine production in vitro and the lymphoproliferative defect of natural measles virus infection. (PubMed id 1914259)9 Ward B.J....Griffin D.E. (Clin. Immunol. Immunopathol. 1991)
    1133. A critical review of immunosuppressive therapy. (PubMed id 1916932)9 Briggs J.D. (Immunol. Lett. 1991)
    1134. The role of CD45RA on human B-cell function: anti-CD45RA antibody (anti-2H4) inhibits the activation of resting B cells and antibody production of activated B cells independently in humans. (PubMed id 1715602)9 Morikawa K....Morikawa S. (Scand. J. Immunol. 1991)
    1135. Mechanism of calcium ionophore and phorbol ester-induced T-cell activation. Accessory cell requirement for T-cell activation. (PubMed id 2017664)9 Hashimoto S....Michalski J.P. (Scand. J. Immunol. 1991)
    1136. Suppressive activity of interleukin 4 on the induction of antigen-specific cytotoxic T cells in humans. (PubMed id 1712006)9 Yamashita U. and Tanaka Y. (Jpn. J. Cancer Res. 1991)
    1137. A longitudinal study on IL-2, sIL-2R, IL-4 and IFN-gamma in multiple sclerosis CSF and serum. (PubMed id 1827837)9 Gallo P....SidAcn A. (J. Neurol. Sci. 1991)
    1138. The role of the transferrin receptor for the activation of human lymphocytes. (PubMed id 1988160)9 Keyna U....Manger B. (Cell. Immunol. 1991)
    1139. Modulation of interleukin 2 internalization and interleukin 2-dependent cell growth by antireceptor antibodies. (PubMed id 1988432)9 Duprez V....Dautry-Varsat A. (J. Biol. Chem. 1991)
    1140. Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori. (PubMed id 1900743)9 Karttunen R. (Clin. Exp. Immunol. 1991)
    1141. Effects of diltiazem upon metabolism and immunosuppressive action of cyclosporine in kidney graft recipients. (PubMed id 1871801)9 Kunzendorf U....Strom T.B. (Transplantation 1991)
    1142. [Serum soluble IL-2 receptor level in patients with sarcoidosis]. (PubMed id 2067152)9 Ina Y....Yamamoto M. (Nihon Kyobu Shikkan Gakkai Zasshi 1991)
    1143. Detection, isolation and functional studies of CD25+ T cells in lymph nodes involved by B-cell non-Hodgkin's lymphomas. (PubMed id 2068535)9 Bonnefoix T....Sotto J.J. (Scand. J. Immunol. 1991)
    1144. Serum and CSF levels of IL-2, sIL-2R, TNF-alpha, and IL-1 beta in chronic progressive multiple sclerosis: expected lack of clinical utility. (PubMed id 1985276)9 Peter J.B....Tourtellotte W.W. (Neurology 1991)
    1145. The role of endogenous opioids and their receptors in the immune system. (PubMed id 1656470)9 Carr D.J. (Proc. Soc. Exp. Biol. Med. 1991)
    1146. Modulating effects on CD25 and CD71 antigen expression by lectin-stimulated T lymphocytes in the elderly. (PubMed id 1770220)9 Antonaci S....Bonomo L. (Immunopharmacol Immunotoxicol 1991)
    1147. Cocaine immunotoxicity: abnormal cytokine production in Hispanic drug users. (PubMed id 1721732)9 Chen G.J....Watson R.R. (Toxicol. Lett. 1991)
    1148. In vitro effect of interleukin-2 on proliferative responses of peripheral blood T cells from leprosy patients. (PubMed id 1781183)9 Choi I.H....Kim S.J. (Yonsei Med. J. 1991)
    1149. Therapy of advanced acute myeloblastic leukemia with cytarabine and interleukin 2. (PubMed id 1910127)9 Butturini A....Castriota Scanderbeg A. (Leuk. Res. 1991)
    1150. Interleukin-1-inhibitor activity induced by respiratory syncytial virus: abrogation of virus-specific and alternate human lymphocyte proliferative responses. (PubMed id 1984478)9 Salkind A.R....Roberts N.J. (J. Infect. Dis. 1991)
    1151. Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes. (PubMed id 1652056)9 Augustine J.A....Abraham R.T. (Mol. Cell. Biol. 1991)
    1152. Prophylaxis of graft-versus-host disease by administration of the murine anti-IL-2 receptor antibody 2A3. (PubMed id 2070147)9 Anasetti C....Stewart P. (Bone Marrow Transplant. 1991)
    1153. Human allogeneic melanoma-reactive T-helper lymphocyte clones: functional analysis of lymphocyte-melanoma interactions. (PubMed id 1835714)9 Radrizzani M....Fossati G. (Int. J. Cancer 1991)
    1154. Characterization of pancreatic T lymphocytes associated with beta cell destruction in the non-obese diabetic (NOD) mouse. (PubMed id 1679332)9 Kay T.W....Harrison L.C. (J. Autoimmun. 1991)
    1155. T-cell activation. IV. Evidence for a functional linkage between MHC class I, interleukin-2 receptor, and interleukin-4 receptor molecules. (PubMed id 1832052)9 Hansen N.Q....Claesson M.H. (Cytokine 1991)
    1156. Human CD4+CD45R0+ and CD4+CD45RA+ T cells synergize in response to alloantigens. (PubMed id 1680701)9 Akbar A.N....Janossy G. (Eur. J. Immunol. 1991)
    1157. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion. (PubMed id 1826793)9 Eugui E.M....Allison A.C. (Scand. J. Immunol. 1991)
    1158. Purification and characterization of the immunostimulatory properties of recombinant human interleukin-1 beta. (PubMed id 1873490)9 Ketlinsky S....Perumov N.D. (Eur. Cytokine Netw. 1991)
    1159. Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. (PubMed id 1939640)9 Kurane I....Ennis F.A. (J. Clin. Invest. 1991)
    1160. Raised serum levels of CD8, CD25 and beta 2-microglobulin in common variable immunodeficiency. (PubMed id 1934593)9 North M.E....Farrant J. (Clin. Exp. Immunol. 1991)
    1161. FK506 lacks the ability to inhibit expression of interleukin-2 receptor beta-chain on human lymphocytes. (PubMed id 1726895)9 Karlsson H. and NAossberger L. (amp 1991)
    1162. Differential regulation by dexamethasone and cyclosporine of human T cells activated by various stimuli. (PubMed id 1654606)9 Furue M. and Ishibashi Y. (Transplantation 1991)
    1163. Interleukin-2 receptor gene expression in kidney transplant recipients treated with cyclosporin A. (PubMed id 1864013)9 Yoshimura N....Imanishi J. (Clin. Exp. Immunol. 1991)
    1164. Lymphokine receptor-directed therapy: a model for immune intervention in leukemia, autoimmunity, and immunodeficiency. (PubMed id 1934612)9 Waldmann T.A. (Clin. Immunol. Immunopathol. 1991)
    1165. [Immunological study on renal cell carcinoma in dialysis patients with acquired cystic disease of kidneys]. (PubMed id 1762269)9 Onishi T....Makino H. (Nippon Hinyokika Gakkai Zasshi 1991)
    1166. Activation of peripheral CD8+ T lymphocytes via CD28 plus CD2: evidence for IL-2 gene transcription mediated by CD28 activation. (PubMed id 1676547)9 Carabasi M.H....Dupont B. (Tissue Antigens 1991)
    1167. Serum interleukin-1 beta levels correlate with neoplastic bulk in hairy cell leukemia. (PubMed id 2072745)9 Cimino G....Mandelli F. (Leukemia 1991)
    1168. Interleukin-4 downregulates the p70 chain of the IL-2 receptor on peripheral blood mononuclear cells. (PubMed id 2060024)9 Lindqvist C....Andersson L.C. (Cell. Immunol. 1991)
    1169. Detection of hyperreactive T cells in multiple myeloma by multivalent cross-linking of the CD3/TCR complex. (PubMed id 1832993)9 Massaia M....Pileri A. (Blood 1991)
    1170. Comparative analysis of cytokine patterns in immunological, infectious, and oncological neurological disorders. (PubMed id 1940975)9 Weller M....WiethAPlter H. (J. Neurol. Sci. 1991)
    1171. Plasma interleukin-2 and a soluble/shed interleukin-2 receptor in serum of patients with Crohn's disease. Effect of cyclosporin. (PubMed id 2370014)9 Brynskov J. and Tvede N. (Gut 1990)
    1172. Interaction between endogenous opioids and IL-2 on PHA-stimulated human lymphocytes. (PubMed id 2394465)9 Kay N.E....Allen J.I. (Immunology 1990)
    1173. Increased serum levels of soluble IL-2 receptor, CD30 and CD8 molecules, and gamma-interferon in angioimmunoblastic lymphadenopathy: possible pathogenetic role of immunoactivation mechanisms. (PubMed id 2119791)9 Pizzolo G....Diamantstein T. (Br. J. Haematol. 1990)
    1174. Immune activation markers to predict AIDS and survival in HIV-1 seropositives. (PubMed id 2125976)9 Fuchs D....Wachter H. (Immunol. Lett. 1990)
    1175. Interleukin-2 receptor expression and interleukin-2 production in bullous pemphigoid. (PubMed id 1973607)9 Schaller J....Haustein U.F. (Arch. Dermatol. Res. 1990)
    1176. Bronchoalveolar T-lymphocytes and subsets in pulmonary tuberculosis and bronchogenic carcinoma. (PubMed id 2345320)9 Pushpakom R....Bovornkitti S. (J Med Assoc Thai 1990)
    1177. Activation of human CD8-positive T cells via the CD8/HLA class I complex. (PubMed id 2105853)9 Bushkin Y....Le J.M. (Cell. Immunol. 1990)
    1178. Monoclonal antibodies and arthritis. (PubMed id 2327319)9 Billingham M.E....Carney S. (Agents Actions 1990)
    1179. Interrelationships between serologic markers of immune activation and T lymphocyte subsets in HIV infection. (PubMed id 1969960)9 Prince H.E....Williams A.E. (J. Acquir. Immune Defic. Syndr. 1990)
    1180. [Detection of the activation of alveolar lymphocytes in alveolar proteinosis]. (PubMed id 2367399)9 Teschler H....Costabel U. (Pneumologie 1990)
    1181. Human blood basophils synthesize interleukin-2 binding sites. (PubMed id 1691935)9 Stockinger H....Knapp W. (Blood 1990)
    1182. T cell activation. II. Activation of human T lymphoma cells by cross-linking of their MHC class I antigens. (PubMed id 2137376)9 Dissing S....Claesson M.H. (Cell. Immunol. 1990)
    1183. IL-4 inhibits the expression of high affinity IL-2 receptors on monoclonal human B cells. (PubMed id 2380552)9 Karray S....Galanaud P. (J. Immunol. 1990)
    1184. In vitro production of interferon-gamma by peripheral blood from patients with Graves' disease, Hashimoto's thyroiditis and rheumatoid arthritis. (PubMed id 1976464)9 Matsubayashi S....VolpAc R. (Clin. Exp. Immunol. 1990)
    1185. T cell responses in acute falciparum malaria. (PubMed id 2283144)9 Ho M. and Webster H.K. (Immunol. Lett. 1990)
    1186. Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation. (PubMed id 1970938)9 Soiffer R.J....Ritz J. (Blood 1990)
    1187. Human IFN-gamma up-regulates IL-2 receptors in mitogen-activated T lymphocytes. (PubMed id 2110548)9 Rodriguez M.A....Abadi I. (Immunology 1990)
    1188. A monoclonal mouse anti-human IL-2 receptor antibody (anti-Tac) will recognize molecules on the surface of Xenopus laevis immunocytes which specifically bind rIL-2 and are only slightly larger than the human Tac protein. (PubMed id 2354864)9 Ruben L.N....Shiigi S. (Immunol. Lett. 1990)
    1189. Serum soluble interleukin-2 receptor is associated with clinical and pathologic disease status in hairy cell leukemia. (PubMed id 1700727)9 Richards J.M....Golomb H.M. (Blood 1990)
    1190. 1,25-Dihydroxyvitamin D3 modulates the effects of interleukin 2 independent of IL-2 receptor binding. (PubMed id 2105168)9 Rigby W.F....Waugh M.G. (Cell. Immunol. 1990)
    1191. Accessory function of interleukin-1 and interleukin-6: preferential costimulation of T4 positive lymphocytes. (PubMed id 1967955)9 Tosato G....Pike S.E. (Blood 1990)
    1192. IL-2-PE40 prevents the development of tumors in mice injected with IL-2 receptor expressing EL4 transfectant tumor cells. (PubMed id 2212661)9 Kozak R.W....Pastan I. (J. Immunol. 1990)
    1193. The effect of desferrithiocin, an oral iron chelator, on T-cell function. (PubMed id 2242426)9 Bierer B.E. and Nathan D.G. (Blood 1990)
    1194. Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography. (PubMed id 2144854)9 Novick D....Rubinstein M. (J. Chromatogr. 1990)
    1195. CD4+ CD45R- suppressor-inducer T-cell clones: requirements for cellular interaction, proliferation and lymphokines for the induction of suppression in peripheral blood mononuclear cells. (PubMed id 1692302)9 Pawelec G. (Immunology 1990)
    1196. Idiopathic pulmonary fibrosis: can cell mediated immunity markers predict clinical outcome? (PubMed id 2118691)9 Meliconi R....Gasbarrini G. (Thorax 1990)
    1197. Affinity of IL-2 receptors and proliferation of mitogen activated lymphocytes in Hodgkin's disease. (PubMed id 2328206)9 Damle R.N....Gangal S.G. (Br. J. Cancer 1990)
    1198. IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T cells. (PubMed id 1968925)9 Martinez O.M....Aronson F.R. (J. Immunol. 1990)
    1199. IL2-PE664Glu, a new chimeric protein cytotoxic to human-activated T lymphocytes. (PubMed id 1975810)9 Lorberboum-Galski H....Pastan I. (J. Biol. Chem. 1990)
    1200. Levamisole meets sulfhydryl requirements of CTLL-2 cells and mediates enhanced proliferative response to mitogen stimulation without increasing interleukin-2 production. (PubMed id 2380743)9 Obiri N.I....O'Connor T.E. (J Biol Response Mod 1990)
    1201. CCA (disodium 4-chloro-2,2'-iminodibenzoate) inhibits progression of human T cell proliferation triggered by PHA. (PubMed id 2118015)9 Katagiri K....Yoshida T. (Clin. Immunol. Immunopathol. 1990)
    1202. Inability of mitogen-activated lymphocytes obtained from patients with malignant primary intracranial tumors to express high affinity interleukin 2 receptors. (PubMed id 2365829)9 Elliott L.H....Roszman T.L. (J. Clin. Invest. 1990)
    1203. Interleukin-2 immunotherapy in children. (PubMed id 2174536)9 Chien C.H. and Hsieh K.H. (Pediatrics 1990)
    1204. The biological significance of soluble interleukin-2 receptors in solid tumors. (PubMed id 2138475)9 Lissoni P....Tancini G. (Eur. J. Cancer 1990)
    1205. [Receptor-mediated cancer therapy--tumoricidal cytokines, adoptive therapy of LAK, TIL]. (PubMed id 1693487)9 Niitsu Y....Kanisawa Y. (amp 1990)
    1206. [The effect of heat shock on mRNA expression in human T lymphocytes]. (PubMed id 2151259)9 Liu Z. (Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1990)
    1207. Characterization of OKT3-initiated lymphokine-activated effectors expanded with interleukin 2 and tumor necrosis factor alpha. (PubMed id 2160321)9 Yang S.C....Grimm E.A. (Cancer Res. 1990)
    1208. Pharmacokinetics of the recombinant fusion protein DAB486IL-2 in animal models. (PubMed id 2225311)9 Bacha P....Rosenblum M. (Cancer Chemother. Pharmacol. 1990)
    1209. Immunologic effects of AS101 in the treatment of cancer patients. (PubMed id 2370878)9 Shani A....Michlin H. (Nat. Immun. Cell Growth Regul. 1990)

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    Entrez Gene: 3560 HGNC: 6009 AceView: IL2RBandC1QTNF6 Ensembl:ENSG00000100385 euGenes: HUgn3560
    ECgene: IL2RB Kegg: 3560 H-InvDB: IL2RB

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IL2RB Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for IL2RB Genetics and Cytogenetics in Oncology and Haematology
    SeattleSNPshttp://pga.gs.washington.edu/data/il2rb/

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