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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IL20RB Gene

protein-coding   GIFtS: 53
GCID: GC03P136665

Interleukin 20 Receptor Beta

(Previous name: fibronectin type III domain containing 6)
(Previous symbol: FNDC6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Interleukin 20 Receptor Beta1 2     IL-20R22 3
FNDC61 2     IL-20RB2 3
Fibronectin Type III Domain Containing 61 2     IL-20 Receptor Subunit Beta2 3
DIRS12 3     Interleukin-20 Receptor II2
IL-20R-beta2 3     Interleukin-20 Receptor Subunit Beta2

External Ids:    HGNC: 60041   Entrez Gene: 538332   Ensembl: ENSG000001745647   OMIM: 6056215   UniProtKB: Q6UXL03   

Export aliases for IL20RB gene to outside databases

Previous GC identifers: GC00U990739 GC03P138161 GC03P134052


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL20RB Gene:
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et
al., 2001 (PubMed 11163236)).(supplied by OMIM, Feb 2009)

GeneCards Summary for IL20RB Gene: 
IL20RB (interleukin 20 receptor beta) is a protein-coding gene. Diseases associated with IL20RB include cblc, and psoriasis, and among its related super-pathways are STAT3 Pathway.

UniProtKB/Swiss-Prot: I20RB_HUMAN, Q6UXL0
Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor
for IL20 and IL24

Gene Wiki entry for IL20RB (Interleukin 20 receptor, beta subunit) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IL20RB gene promoter:
         AhR   AML1a   Pax-2   Pax-2a   Arnt   Meis-1b   YY1   CP2   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL20RB promoter sequence
   Search SABiosciences Chromatin IP Primers for IL20RB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL20RB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.3   Ensembl cytogenetic band:  3q22.3   HGNC cytogenetic band: 3q22.3

IL20RB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL20RB gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P136665:  view genomic region     (about GC identifiers)

Start:
136,665,072 bp from pter      End:
136,729,927 bp from pter
Size:
64,856 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: I20RB_HUMAN, Q6UXL0 (See protein sequence)
Recommended Name: Interleukin-20 receptor subunit beta precursor  
Size: 311 amino acids; 35076 Da
Subunit: Heterodimer with IL20RA and heterodimer with IL22RA1
Subcellular location: Membrane; Single-pass type I membrane protein (By similarity)
1 PDB 3D structure from and Proteopedia for IL20RB:
4DOH (3D)    
Secondary accessions: B4DL40 Q6P438 Q8TAJ7

Explore the universe of human proteins at neXtProt for IL20RB: NX_Q6UXL0

Explore proteomics data for IL20RB at MOPED 

IL20RB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

IL20RB Protein Expression

REFSEQ proteins: NP_653318.2  
ENSEMBL proteins: 
 ENSP00000328133   ENSP00000418637   ENSP00000417437   ENSP00000420725   ENSP00000311979  

Human Recombinant Protein Products for IL20RB: 
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Sino Biological Cell Lysate for IL20RB 
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Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral to membrane IEA--

IL20RB for ontologies           About GeneDecksing



IL20RB Antibody Products: 
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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
FN3: Fibronectin type III domain containing
IL: Interleukins and interleukin receptors

IUPHAR Guide to PHARMACOLOGY protein family classification: Interleukin 20 receptor, β subunit 
IL-10 receptor family

3 InterPro protein domains:
 IPR003961 Fibronectin_type3
 IPR015373 Interferon_alpha/beta_rcpt_bsu
 IPR013783 Ig-like_fold

Graphical View of Domain Structure for InterPro Entry Q6UXL0

ProtoNet protein and cluster: Q6UXL0

UniProtKB/Swiss-Prot: I20RB_HUMAN, Q6UXL0
Similarity: Belongs to the type II cytokine receptor family
Similarity: Contains 2 fibronectin type-III domains


IL20RB for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: I20RB_HUMAN, Q6UXL0
Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor
for IL20 and IL24

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
GO:0042015interleukin-20 binding IEA--
     
IL20RB for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for IL20RB:
 Increased cilium length after  

     5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Il20rb):
 cellular  hematopoietic system  homeostasis/metabolism  immune system  normal 

IL20RB for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Il20rbtm1Uwe for IL20RB

   inGenious Targeting Laboratory - Custom generated mouse model solutions for IL20RB 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IL20RB

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IL20RB 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IL20RB 

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL20RB
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SwitchGear 3'UTR luciferase reporter plasmidIL20RB 3' UTR sequence
Inhib. RNA
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Gene Editing
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RB


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for IL20RB About                                                                                                See pathways by source

SuperPathContained pathways About
1PEDF Induced Signaling
Cytokine-cytokine receptor interaction0.43
2Jak-STAT signaling pathway
Jak-STAT signaling pathway

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways




2         Kegg Pathways  (Kegg details for IL20RB):
    Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway


IL20RB for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL20RB

STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

5/20 Interacting proteins for IL20RB (Q6UXL03 ENSP000003281334) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
InteractantInteraction Details
GeneCardExternal ID(s)
IL20Q9NYY13, ENSP000003560634I2D: score=2 STRING: ENSP00000356063
IL19Q9UHD03I2D: score=1 
IL24Q130073I2D: score=1 
IL20RAENSP000003149764STRING: ENSP00000314976
CBLENSP000002640334STRING: ENSP00000264033
About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001808negative regulation of type IV hypersensitivity IEA--
GO:0002437inflammatory response to antigenic stimulus IEA--
GO:0002765immune response-inhibiting signal transduction IEA--
GO:0032689negative regulation of interferon-gamma production IEA--
GO:0032703negative regulation of interleukin-2 production IEA--

IL20RB for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IL20RB (I20RB)

Search CenterWatch for drugs/clinical trials and news about IL20RB / I20RB

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IL20RB gene: 
NM_144717.3  

Unigene Cluster for IL20RB:

Interleukin 20 receptor beta
Hs.61232  [show with all ESTs]
Unigene Representative Sequence: NM_144717
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000484501 ENST00000329582(uc003eri.2 uc003erj.2) ENST00000469964
ENST00000491483 ENST00000475972(uc010hud.2) ENST00000309741
miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL20RB
7 QIAGEN miScript miRNA Assays for microRNAs that regulate IL20RB:
hsa-miR-3616-5p hsa-miR-573 hsa-miR-3647-5p hsa-miR-3155 hsa-miR-3155b hsa-miR-484 hsa-miR-570
SwitchGear 3'UTR luciferase reporter plasmidIL20RB 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for IL20RB
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL20RB
Clone
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GenScript: all cDNA clones in your preferred vector: IL20RB (NM_144717)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IL20RB
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL20RB
Sirion Biotech Customized lentivirus for stable overexpression of IL20RB 
                     Customized lentivirus expression plasmids for stable overexpression of IL20RB 
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for IL20RB
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL20RB

Additional mRNA sequence: 

AJ431617.1 AK296832.1 AK316084.1 AY358305.1 BC027449.1 BC063696.1 

5 DOTS entries:

DT.101977165  DT.410873  DT.100021077  DT.99997292  DT.95321065 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for IL20RB    About this scheme

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
SP1:                                                                  
SP2:              -                       -                           
SP3:                                      -           -               


ECgene alternative splicing isoforms for IL20RB

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IL20RB expression in normal human tissues (normalized intensities)      IL20RB embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTTGTTGTGC
IL20RB Expression
About this image


IL20RB expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/14 selected tissues (see all 14) fully expand
 
 Epithelium (Uncategorized)    fully expand to see all 4 entries
         Human Bronchial Epithelial Cells (HBEpiC)   
 
 Fibroblast
         Human Prostate Fibroblasts (HPrF)   
 
 Lung (Respiratory System)    fully expand to see all 3 entries
         Human Bronchial Epithelial Cells (HBEpiC)   
 
 Epidermis (Integumentary System)    fully expand to see all 2 entries
         Human EpiDermal Keratinocytes (HEK)   
 
 Dermis (Uncategorized)    fully expand to see all 2 entries
         Human Dermal Fibroblasts-adult (HDF-a)   

See IL20RB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IL20RB

SOURCE GeneReport for Unigene cluster: Hs.61232

UniProtKB/Swiss-Prot: I20RB_HUMAN, Q6UXL0
Tissue specificity: Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin

    SABiosciences Expression via Pathway-Focused PCR Array including IL20RB: 
          Interferons & Receptors in human mouse rat

Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RB

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for IL20RB gene from 4/10 species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Il20rb1 , 5 interleukin 20 receptor beta1, 5 82.24(n)1
77.78(a)1
  9 (52.66 cM)5
2132081  NM_001033543.31  NP_001028715.21 
 1004577195 
chicken
(Gallus gallus)
Aves IL20RB1 interleukin 20 receptor beta 63.04(n)
51.61(a)
  768437  XM_001231359.1  XP_001231360.1 
lizard
(Anolis carolinensis)
Reptilia IL20RB6
interleukin 20 receptor beta
45(a)
1 ↔ 1
GL343276.1(1661914-1674725)
zebrafish
(Danio rerio)
Actinopterygii crfb166
cytokine receptor family member B16
21(a)
1 ↔ 1
2(5164062-5178585)


ENSEMBL Gene Tree for IL20RB (if available)
TreeFam Gene Tree for IL20RB (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/935 SNPs in IL20RB are shown (see all 935)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1909889321,2
--136674741(+) GGAATC/TAGGAA 1 -- us2k10--------
rs1809274961,2
--136675362(+) ATGCAC/TTCAAT 1 -- us2k10--------
rs1449410861,2
--136675434(+) CATGAG/TAAACC 1 -- us2k10--------
rs1490710421,2
--136675485(+) TAGCTA/CCCTCA 1 -- us2k10--------
rs1859050731,2
--136675508(+) CTTCAA/GTCTGG 1 -- us2k10--------
rs1134135611,2
F--136675547(+) CACAAC/ACTTTT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
rs1386678841,2
--136675607(+) TTCCTA/TTGACC 1 -- us2k10--------
rs1924927221,2
--136675706(+) TTCTCA/GCCATT 1 -- us2k10--------
rs738646471,2
C,F--136675726(+) TTCTCG/ATGTTG 1 -- us2k12Minor allele frequency- A:0.27WA 120
rs605417831,2
C--136675776(+) TTTTT-/TTTCCAGA 1 -- us2k10--------

HapMap Linkage Disequilibrium report for IL20RB (136665072 - 136729927 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for IL20RB:    About this table     
Variant IDTypeSubtypePubMed ID
nsv877534CNV Loss21882294
nsv524856CNV Loss19592680


Human Gene Mutation Database (HGMD): IL20RB
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing IL20RB
DNA2.0 Custom Variant and Variant Library Synthesis for IL20RB

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 605621    OMIM disorders: --

3 diseases for IL20RB:    About MalaCards
cblc    psoriasis    hypoxia

1 disease from the University of Copenhagen DISEASES database for IL20RB:
Psoriasis

IL20RB for disorders           About GeneDecksing

Genetic Association Database (GAD): IL20RB
Human Genome Epidemiology (HuGE) Navigator: IL20RB (1 document)

Export disorders for IL20RB gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for IL20RB gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with IL20RB)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Interleukin 20: discovery, receptor identification, and role in epidermal function. (PubMed id 11163236)1, 2, 3 Blumberg H.... Chandrasekher Y.A. (2001)
  2. Association analysis of IL20RA and IL20RB genes in psoriasis. (PubMed id 18480827)1, 4 Kingo K....Koks S. (2008)
  3. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. (PubMed id 19043545)1, 4 Gieger C....Suhre K. (2008)
  4. IL-20: biological functions and clinical implications . (PubMed id 16703417)1, 3 Wei C.C....Chang M.S. (2006)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  6. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
  7. Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. (PubMed id 14580208)1, 2 Pletnev S.... Zdanov A. (2003)
  8. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
  9. Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. (PubMed id 12351624)1, 2 Parrish-Novak J.... Chandrasekher Y.A. (2002)
  10. STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. (PubMed id 11564763)1, 2 Dumoutier L.... Renauld J.-C. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 53833 HGNC: 6004 Ensembl:ENSG00000174564 euGenes: HUgn53833 ECgene: IL20RB Kegg: 53833
H-InvDB: IL20RB

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for IL20RB Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for IL20RB gene:
Search GeneIP for patents involving IL20RB

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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