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IL20RA Gene

protein-coding   GIFtS: 61
GCID: GC06M137321

Interleukin 20 Receptor, Alpha

  See IL20RA-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interleukin 20 Receptor, Alpha1 2     Class II Cytokine Receptor ZCYTOR72
Cytokine Receptor Family 2 Member 82 3     Interleukin-20 Receptor I2
CRF2-82 3     Interleukin-20 Receptor Subunit Alpha2
IL-20R-alpha2 3     ZcytoR73
IL-20R12 3     Cytokine Receptor Class-II Member 83
IL-20RA2 3     IL-20 Receptor Subunit Alpha3

External Ids:    HGNC: 60031   Entrez Gene: 538322   Ensembl: ENSG000000164027   OMIM: 6056205   UniProtKB: Q9UHF43   

Export aliases for IL20RA gene to outside databases

Previous GC identifers: GC06M136944 GC06M137168 GC06M137301 GC06M137362 GC06M134884


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IL20RA Gene:
This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the
receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor
is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and
interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing
results in multiple transcript variants. (provided by RefSeq, Jul 2013)

GeneCards Summary for IL20RA Gene:
IL20RA (interleukin 20 receptor, alpha) is a protein-coding gene. Diseases associated with IL20RA include psoriasis. GO annotations related to this gene include interleukin-20 binding. An important paralog of this gene is IL22RA2.

UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for
IL26

Gene Wiki entry for IL20RA (Interleukin 20 receptor, alpha subunit) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IL20RA gene promoter:
         AREB6   STAT1   POU2F1   POU2F1a   STAT1beta   Cart-1   STAT3   Nkx2-5   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL20RA promoter sequence
   Search Chromatin IP Primers for IL20RA

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IL20RA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.3   Ensembl cytogenetic band:  6q23.3   HGNC cytogenetic band: 6q23.3

IL20RA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL20RA gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M137321:  view genomic region     (about GC identifiers)

Start:
137,321,108 bp from pter      End:
137,366,298 bp from pter
Size:
45,191 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4 (See protein sequence)
Recommended Name: Interleukin-20 receptor subunit alpha precursor  
Size: 553 amino acids; 62485 Da
Subunit: Heterodimer with IL20RB and heterodimer with IL10RB
1 PDB 3D structure from and Proteopedia for IL20RA:
4DOH (3D)    
Secondary accessions: Q14CW2 Q6UWA9 Q96SH8
Alternative splicing: 2 isoforms:  Q9UHF4-1   Q9UHF4-2   

Explore the universe of human proteins at neXtProt for IL20RA: NX_Q9UHF4

Explore proteomics data for IL20RA at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn42, Asn83, Asn91, Asn182, Asn191, Asn200

  • See IL20RA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001265651.1  NP_001265652.1  NP_001265653.1  NP_055247.3  

    ENSEMBL proteins: 
     ENSP00000314976   ENSP00000356720   ENSP00000437843   ENSP00000356722  

    IL20RA Human Recombinant Protein Products:

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    R&D Systems Recombinant & Natural Proteins for IL20RA (IL-20 R alpha)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for IL20RA
    OriGene Protein Over-expression Lysate for IL20RA
    OriGene Custom MassSpec
    OriGene Custom Protein Services for IL20RA
    GenScript Custom Purified and Recombinant Proteins Services for IL20RA
    Novus Biologicals IL20RA Protein
    Novus Biologicals IL20RA Lysate
    Sino Biological Recombinant Protein for IL20RA
    Sino Biological Cell Lysate for IL20RA
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for IL20RA 

    IL20RA Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of IL20RA
    R&D Systems Antibodies for IL20RA (IL-20 R alpha)
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    Novus Biologicals IL20RA Antibodies
    Abcam antibodies for IL20RA
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for IL20RA
    LSBio Antibodies in human, mouse, rat for IL20RA

    IL20RA Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for IL20RA 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IL: Interleukins and interleukin receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: Interleukin 20 receptor, alpha subunit
    IL-10 receptor family

    4 InterPro protein domains:
     IPR003961 Fibronectin_type3
     IPR015373 Interferon_alpha/beta_rcpt_bsu
     IPR013783 Ig-like_fold
     IPR015713 IL-20_rcpt_alpha

    Graphical View of Domain Structure for InterPro Entry Q9UHF4

    ProtoNet protein and cluster: Q9UHF4

    1 Blocks protein domain: IPB001187 Tissue factor

    UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
    Similarity: Belongs to the type II cytokine receptor family
    Similarity: Contains 2 fibronectin type-III domains


    Find genes that share domains with IL20RA           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: I20RA_HUMAN, Q9UHF4
    Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for
    IL26

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0042015interleukin-20 binding IEA--
         
    Find genes that share ontologies with IL20RA           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for IL20RA:
     Increased cell number in G1, s 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Il20ra):
     cellular  hematopoietic system  immune system  skeleton 

    Find genes that share phenotypes with IL20RA           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Il20ratm1.1Misc for IL20RA

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IL20RA
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IL20RA

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IL20RA
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IL20RA

    miRNA
    Products:
        
    miRTarBase miRNAs that target IL20RA:
    hsa-mir-26b-5p (MIRT029093)

    Block miRNA regulation of human, mouse, rat IL20RA using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IL20RA (see all 13):
    hsa-miR-3163 hsa-miR-550a hsa-miR-4288 hsa-miR-589* hsa-miR-632 hsa-miR-346 hsa-miR-944 hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidIL20RA 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IL20RA
    Predesigned siRNA for gene silencing in human, mouse, rat IL20RA

    Gene Editing
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    OriGene ORF clones in mouse, rat for IL20RA
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IL20RA (NM_014432)
    Sino Biological Human cDNA Clone for IL20RA
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IL20RA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL20RA

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    Browse ESI BIO Cell Lines and PureStem Progenitors for IL20RA 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RA


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    I20RA_HUMAN, Q9UHF4: Membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    plasma membrane2
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with IL20RA           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IL20RA About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1PEDF Induced Signaling
    STAT3 Pathway0.47
    Cytokine-cytokine receptor interaction0.43
    2Akt Signaling
    Akt Signaling0.60
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    3TGF-Beta Pathway
    MAPK Family Pathway0.60
    4PAK Pathway
    Antioxidant Action of Vitamin-C0.56
    5ERK Signaling
    Molecular Mechanisms of Cancer0.51


    Find genes that share SuperPaths with IL20RA           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IL20RA (see all 7)
        STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    p38 Signaling
    Akt Signaling



    2 Kegg Pathways  (Kegg details for IL20RA):
        Cytokine-cytokine receptor interaction
    Jak-STAT signaling pathway

        Pathway & Disease-focused RT2 Profiler PCR Arrays including IL20RA: 
              Interferons & Receptors in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for IL20RA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for IL20RA (Q9UHF43 ENSP000003149764) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IL19Q9UHD03, ENSP000003430004I2D: score=1 STRING: ENSP00000343000
    IL20Q9NYY13, ENSP000003560634I2D: score=1 STRING: ENSP00000356063
    IL24Q130073, ENSP000002949844I2D: score=1 STRING: ENSP00000294984
    IL26Q9NPH93I2D: score=1 
    MLH1P406923I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019221cytokine-mediated signaling pathway IEA--
    GO:0045124regulation of bone resorption IEA--
    GO:2001244positive regulation of intrinsic apoptotic signaling pathway IEA--

    Find genes that share ontologies with IL20RA           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IL20RA (I20RA)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IL20RA gene (4 alternative transcripts): 
    NM_001278722.1  NM_001278723.1  NM_001278724.1  NM_014432.3  

    Unigene Cluster for IL20RA:

    Interleukin 20 receptor, alpha
    Hs.445868  [show with all ESTs]
    Unigene Representative Sequence: NM_014432
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000316649(uc003qhi.3 uc011edl.2) ENST00000468393 ENST00000367746
    ENST00000461799 ENST00000460306 ENST00000541547 ENST00000367748(uc003qhj.3 uc003qhk.3 uc010kgy.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IL20RA using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IL20RA (see all 13):
    hsa-miR-3163 hsa-miR-550a hsa-miR-4288 hsa-miR-589* hsa-miR-632 hsa-miR-346 hsa-miR-944 hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidIL20RA 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IL20RA
    Predesigned siRNA for gene silencing in human, mouse, rat IL20RA
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IL20RA (NM_014432)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL20RA
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IL20RA
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IL20RA
      QuantiTect SYBR Green Assays in human, mouse, rat IL20RA
      QuantiFast Probe-based Assays in human, mouse, rat IL20RA

    Additional mRNA sequence: 

    AF184971.1 AJ420490.1 AK098312.1 AK297121.1 AK307072.1 AK315293.1 AY358883.1 BC113574.1 
    BC113602.1 

    6 DOTS entries:

    DT.212820  DT.100748883  DT.99935447  DT.95357173  DT.91967433  DT.97808767 

    Selected AceView cDNA sequences (see all 66):

    AI381033 CB128408 AI350971 NM_014432 BM674665 AA514541 BQ185521 BU579846 
    AI308941 AA583432 AA299011 AY358883 AI912054 BM683620 AA632915 CK299400 
    BM970319 CA454197 AI675877 BG743223 BU580093 BQ187458 BG741175 AW340967 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for IL20RA (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b · 10c
    SP1:                          -     -     -     -     -                             -     -                                       
    SP2:                          -     -     -     -     -           -                 -     -                                       
    SP3:                          -     -     -     -     -                                                                           
    SP4:                                      -     -     -           -     -           -     -                                       
    SP5:                          -     -                                                                                             


    ECgene alternative splicing isoforms for IL20RA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IL20RA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGGTCTCTT
    IL20RA Expression
    About this image


    IL20RA expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Bone marrow-derived mesenchymal stem cells
     
     Mesenchymal Stem Cells
             Bone marrow-derived mesenchymal stem cells
     
     Epiblast (Early Embryonic Tissues)    fully expand to see all 2 entries
             Epiblast Stem Cell line 5
    IL20RA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IL20RA Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.445868

    UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
    Tissue specificity: Widely expressed with highest levels in skin and testis and high levels in brain. Highly
    expressed in psoriatic skin

        Pathway & Disease-focused RT2 Profiler PCR Arrays including IL20RA: 
              Interferons & Receptors in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for IL20RA
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IL20RA
    QuantiTect SYBR Green Assays in human, mouse, rat IL20RA
    QuantiFast Probe-based Assays in human, mouse, rat IL20RA
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IL20RA gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Il20ra1 , 5 interleukin 20 receptor, alpha1, 5 74.47(n)1
    64.99(a)1
      10 (8.76 cM)5
    2373131  NM_172786.21  NP_766374.11 
     197125875 
    chicken
    (Gallus gallus)
    Aves IL20RA1 interleukin 20 receptor, alpha 55.49(n)
    43.47(a)
      421686  XM_419723.4  XP_419723.1 
    zebrafish
    (Danio rerio)
    Actinopterygii crfb81 cytokine receptor family member b8 45.25(n)
    34.49(a)
      556728  NM_001079676.2  NP_001073144.2 


    ENSEMBL Gene Tree for IL20RA (if available)
    TreeFam Gene Tree for IL20RA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IL20RA gene
    IL22RA22  IL22RA12  

    Find genes that share paralogs with IL20RA           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IL20RA (see all 1064)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1384243181,2
    C,Funtested1137323071(+) ATGTTC/TCTTGT 2 E G mis12Minor allele frequency- T:0.00NA EU 5871
    rs3725495211,2
    C--137320660(+) AGAATA/GTCAAT 1 -- ds50010--------
    rs1409450881,2
    --137320703(+) TAAAAC/GCAACT 1 -- ds50010--------
    rs1831276921,2
    C--137320723(+) ATTCCC/TCTTTT 1 -- ds50010--------
    rs9274431,2
    C,F,O,A,H--137320867(+) TATGTT/CTAAAT 1 -- ds500125Minor allele frequency- C:0.27MN NS EA NA WA CSA 2344
    rs1868770401,2
    --137320973(+) TAAGTA/GCCTTC 1 -- ds50010--------
    rs9274441,2
    C,F,A,H--137320996(+) CTTTTT/AATCCT 1 -- ds500113Minor allele frequency- A:0.19MN NS EA NA WA CSA 854
    rs788946781,2
    C,F--137321009(+) AAACAG/ACCCTA 1 -- ds50011Minor allele frequency- A:0.06WA 118
    rs1913376821,2
    --137321065(+) TATTAA/GGTACT 1 -- ds50010--------
    rs1389619111,2
    --137321298(+) TGAAAC/TTGTTT 1 -- ut310--------
    rs755232021,2
    C,F--137321322(+) ATCACG/AAAAGG 1 -- ut311Minor allele frequency- A:0.06WA 118
    rs412889691,2
    C,F--137321336(+) TGACCC/ACAGAA 1 -- ut311Minor allele frequency- A:0.04NA 120
    rs1421422081,2
    C--137321366(+) TTGTCA/TGCCTG 1 -- ut310--------
    rs354794041,2
    C,F,H--137321372(+) GCCTGT/CACCAA 1 -- ut3113Minor allele frequency- C:0.08NS NA WA 1596
    rs10592321,2
    C,F,A,H--137321402(-) GATATC/GACCCA 1 -- ut31 ese318Minor allele frequency- G:0.26MN NA EA NS WA CSA 1190
    rs1850506591,2
    C--137321436(+) GGATTA/G/TTGAGT 2 -- ut310--------
    rs1894307941,2
    --137321470(+) TAAGGA/CAAACC 1 -- ut310--------
    rs781324801,2
    C,F--137321547(+) ATAGAT/CTTTGT 1 -- ut311Minor allele frequency- C:0.06WA 118
    rs1458405271,2
    --137321568(+) AGCAGC/TGTGAC 1 -- ut310--------
    rs1932026211,2
    --137321697(+) TAATAA/GACTCT 1 -- ut310--------
    rs1384230171,2
    --137321817(+) TGAACA/GACTGC 1 -- ut310--------
    rs14751191,2
    C,F,A,H--137321910(+) TATCTG/TTTTGA 1 -- ut3121Minor allele frequency- N:0.00EA NA MN NS WA 2738
    rs1851879321,2
    C--137321988(+) TGAGAA/GACAAT 1 -- ut310--------
    rs1424121561,2
    C--137321993(+) GACAAG/TAAGCC 1 -- ut310--------
    rs1900904181,2
    --137322005(+) CTACTA/GAATTA 1 -- ut310--------
    rs412889711,2
    C,F--137322047(+) TACTCG/ATTTAT 1 -- ut311Minor allele frequency- A:0.01NA 120
    rs1813373661,2
    --137322100(+) CTTAAA/GGTAGC 1 -- ut310--------
    rs1853666411,2
    --137322121(+) TGATAC/TCATGA 1 -- ut310--------
    rs7719561,2
    C,F,H--137322195(+) ACATGT/CGACCA 1 -- ut31 ese322Minor allele frequency- C:0.08MN NS EA NA WA CSA 1932
    rs1174828431,2
    F--137322251(+) CTGCTC/TGCAAT 1 -- ut311Minor allele frequency- T:0.01EA 120
    rs1439651931,2
    --137322291(+) AAAATA/GAGTGA 1 -- ut310--------
    rs1486020841,2
    C--137322308(+) GGAAAC/TATTTT 1 -- ut310--------
    rs765784051,2
    C,F--137322426(+) TGCACC/ACAGTC 1 -- ut311Minor allele frequency- A:0.06WA 118
    rs1882748601,2
    --137322462(+) TCTGCA/GTAGAA 1 -- ut310--------
    rs1808003401,2
    --137322518(+) GAGACA/CTACAT 1 -- ut310--------
    rs1411670701,2
    --137322628(+) CTTTAC/TGGCTG 1 -- ut310--------
    rs1864393361,2
    C--137322720(+) ATAACC/GCCCAT 2 A G mis10--------
    rs1997045331,2
    C--137322803(+) CTAGAT/CAGAAG 2 /L syn11Minor allele frequency- C:0.00EU 1323
    rs2005922281,2
    C--137322820(+) CTCTCC/TGAGCC 2 R G mis11Minor allele frequency- T:0.00EU 1321
    rs2016847751,2
    --137322824(+) CCGAGA/CCCATC 2 G syn10--------
    rs1489596061,2
    C,F--137322827(+) AGCCCA/GTCCCC 2 D syn12Minor allele frequency- G:0.00NA EU 5871
    rs1431116441,2
    C,F--137322833(+) TCCCCA/C/GTCAGA 3 D E mis12NA EU 5871
    rs754090751,2
    C,F--137322878(+) GACAGC/AGAAGG 2 /S syn11Minor allele frequency- A:0.00NA 4548
    rs1884396281,2
    C--137322980(+) GCCAGG/AGGGTC 2 /P syn11Minor allele frequency- A:0.00EU 1323
    rs2020284811,2
    --137323005(+) GAGGGA/GTGTAT 2 T I mis10--------
    rs1378919031,2
    C,F--137323013(+) TATGAG/ATACTG 2 /Y syn12Minor allele frequency- A:0.00NA EU 5875
    rs1434486741,2
    C--137323017(+) AGTACT/CGTAAC 2 /Q /R mis11Minor allele frequency- C:0.00NA 4552
    rs1457898221,2
    C,F--137323046(+) GCCAAC/TGCTGC 2 A syn12Minor allele frequency- T:0.00NA EU 5875
    rs1492736401,2
    C,F--137323081(+) TGTGGA/GCACCT 2 P S mis11Minor allele frequency- G:0.00NA 4550
    rs2021103231,2
    C--137323155(+) ATTCAT/CATTCA 2 /Y /C mis11Minor allele frequency- C:0.00EU 1317
    rs13426421,2,,4
    C,F,O,A,H--137323213(-) CTTCTC/TTCACC 2 L F mis1 ese3114Minor allele frequency- N:0.00EA NS MN NA PA EU CA WA CSA 13057
    rs2009346651,2
    --137323287(+) GTTTCA/GCCTCC 2 A V mis10--------
    rs1400120851,2
    C,F--137323353(+) ATACAT/GCACTG 2 /D /A mis11Minor allele frequency- G:0.00NA 4508
    rs2003467961,2
    --137323386(+) CCTGAC/TGAGAA 2 H R mis10--------
    rs1435528621,2
    C,F--137323395(+) AAATTT/CTAGAA 2 /K /R mis12Minor allele frequency- C:0.00NA EU 5423
    rs1508276761,2
    C,F--137323419(+) TGAGGG/TTGATA 2 N T mis11Minor allele frequency- T:0.00NA 3572
    rs1868107451,2
    --137323513(+) AGAATC/GATTTT 1 -- int10--------
    rs1166435171,2
    F--137323696(+) TGGAAG/TCGAGA 1 -- int11Minor allele frequency- T:0.01WA 118
    rs559741091,2
    C--137323710(+) GATTCG/ACTGGG 1 -- int12Minor allele frequency- A:0.08NA 122
    rs559600111,2
    C--137323750(+) TGGGGC/TGTTGG 1 -- int12Minor allele frequency- T:0.08NA 122
    rs94946271,2
    C,F,A,H--137323836(+) GCCACA/TTGAAG 1 -- int17Minor allele frequency- T:0.08NS EA WA CSA 537
    rs1398127931,2
    C--137324006(+) ATATAC/TGAGCA 1 -- int10--------
    rs1917202871,2
    --137324035(+) TACACC/TATTCT 1 -- int10--------
    rs1831171201,2
    --137324232(+) TTAACG/TTTACA 1 -- int10--------
    rs1452249141,2
    C--137324366(+) TGAAAC/GCTGAA 1 -- int10--------
    rs1476038141,2
    --137324430(+) TGTTAC/TCATGT 1 -- int10--------
    rs21858051,2
    C,F,H--137324515(-) GTGCTG/AAAGGG 1 -- int17Minor allele frequency- A:0.01EA NS NA 720
    rs735606341,2
    C,F--137324561(+) TTCTTG/CCTTCT 1 -- int12Minor allele frequency- C:0.09WA 120
    rs17440611,2
    C,F,A,H--137324655(+) ACTCTC/TGCCTG 1 -- int120Minor allele frequency- T:0.13NS EA NA 2298
    rs1405097331,2
    --137324930(+) CTCCTC/TATCTG 1 -- int10--------
    rs1500021311,2
    --137325282(+) AGTCAA/GCTAAT 1 -- int10--------
    rs17440631,2
    C,A--137325297(+) AAAGCG/TTTTTT 1 -- int1 trp35Minor allele frequency- T:0.10NA CSA 10
    rs346666751,2
    C--137325311(+) TTTTT-/GTTTTTT
    TTTTTG
    /TTT
    TTTTT
    2 -- int1 cds11NA 2
    rs9679061,2
    C,F,A,H--137325389(+) CTTGCT/CGCAAT 1 -- int189Minor allele frequency- C:0.06NS EA PA EU CA WA NA CSA 4630
    rs1171759911,2
    F--137325405(+) TCTCCC/TGGGTT 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1871059031,2
    --137325438(+) CTCCCA/GAGTAG 1 -- int10--------
    rs1452775811,2
    C--137325462(+) CATGCA/GTTACC 1 -- int10--------
    rs1915891461,2
    --137325476(+) TCCAGC/TTAATT 1 -- int10--------
    rs1822882071,2
    --137325564(+) TGCCTC/TGGCCA 1 -- int10--------
    rs1142447161,2
    F--137325611(+) CCCAGC/GCCAGA 1 -- int11Minor allele frequency- G:0.08WA 118
    rs802960881,2
    C,F--137325708(+) GTCCTC/GCTGGA 1 -- int11Minor allele frequency- G:0.08WA 118
    rs1866207711,2
    C--137325747(+) CACACA/CAAGTA 1 -- int10--------
    rs1392828381,2
    C,F--137325788(+) CCAACG/ATGGAT 2 /H syn12Minor allele frequency- A:0.00NA EU 5867
    rs1500228021,2
    C--137325825(+) CAGAAA/CAAAGA 2 C F mis11Minor allele frequency- C:0.00NA 4550
    rs15554981,2,,4
    C,F,O,A,H--137325847(+) AGATAT/CGGGCA 2 /I /V mis1 ese3103Minor allele frequency- C:0.14MN NS EA PA EU CA WA NA CSA 11978
    rs58803231,2
    C--137325902(+) TCTGT-/A/AA  
            
    AAAAA
    1 -- int10--------
    rs58803241,2
    C--137325916(+) AAAAA-/A/AA  
            
    GGTGG
    1 -- int1 trp31NA 2
    rs1432629001,2
    --137326071(+) AGCGGA/TCTCAG 1 -- int10--------
    rs758903981,2
    F--137326093(+) TCCCTG/CACAAG 1 -- int11Minor allele frequency- C:0.01WA 118
    rs16266801,2
    C,F,O,A,H--137326103(+) GAGACA/GGTCTG 1 -- int1110Minor allele frequency- G:0.25NS NA EA PA EU CA WA CSA 6862
    rs15554991,2
    C,F,H--137326148(+) CTAAGA/GATACA 1 -- int126Minor allele frequency- G:0.08NS EA NA WA CSA 2172
    rs1931101951,2
    C--137326187(+) CCATCA/GTATGT 1 -- int10--------
    rs1855598821,2
    --137326203(+) TATGAG/TATTCA 1 -- int10--------
    rs15555001,2
    C,F,O,A,H--137326234(+) AGTAAA/GTGTAT 1 -- int1100Minor allele frequency- G:0.12NA EA NS PA EU CA WA CSA 6056
    rs799588711,2
    C,F--137326257(+) TAAGTC/AACAGA 1 -- int11Minor allele frequency- A:0.06WA 118
    rs1513239771,2
    C--137326288(+) CCCTCC/TAGTGA 1 -- int10--------
    rs774843101,2
    --137326298(+) AAGATC/TCCATT 1 -- int10--------
    rs1458986741,2
    C--137326513(+) CTTCCC/TGGGCC 1 -- int10--------
    rs1383953431,2
    --137326552(+) AAGTCC/TGCAGA 1 -- int10--------
    rs17440651,2
    C,F,A,H--137326635(+) CTGATG/AACTAG 1 -- int125Minor allele frequency- A:0.13NS EA NA 2784
    rs1429753631,2
    C--137326646(+) AGCTCA/GTTGTG 1 -- int10--------
    rs170659631,2
    C,F,H--137326647(+) GCTCAT/CTGTGA 1 -- int114Minor allele frequency- C:0.06NA NS EA CSA WA 1612
    rs1501095591,2
    C--137326657(+) ACTAGC/TTCATA 1 -- int10--------
    rs17752961,2
    C,F,A,H--137326804(-) AAAAAC/AAACAA 1 -- int16Minor allele frequency- A:0.41WA NA EA 364
    rs1385002131,2
    --137327040(+) CTCTAC/TGATCC 1 -- int10--------
    rs117542001,2
    C,F,A,H--137327093(+) TAAATA/GTATCG 1 -- int110Minor allele frequency- G:0.15NS EA NA 658
    rs729715301,2
    C,F--137327201(+) AAGTCC/TGAGTG 1 -- int11Minor allele frequency- T:0.07NA 120
    rs753320531,2
    F--137327202(+) AGTCCG/AAGTGT 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1492438191,2
    C--137327343(+) AAAGCA/GAAACA 1 -- int10--------
    rs37994821,2
    C,F--137327401(+) GTTCCG/ACATGC 1 -- int11Minor allele frequency- A:0.01EA 1472
    rs729715311,2
    --137327437(+) AAGGAA/GCACAT 1 -- int10--------
    rs1884746191,2
    --137327496(+) CTGCGG/TGTGTC 1 -- int10--------
    rs1930715121,2
    --137327512(+) ACCACC/TTGCCC 1 -- int10--------
    rs766134001,2
    F--137327577(+) ATTGAG/CCCTGT 1 -- int12Minor allele frequency- C:0.10CSA WA 120
    rs1841236221,2
    --137327744(+) TGATTA/GTTCAG 1 -- int10--------
    rs48962281,2
    C,F,A,H--137327814(+) TAGCAC/TGGGTT 1 -- int120Minor allele frequency- T:0.40NS EA NA WA 2482
    rs1394634871,2
    --137327837(+) TAGAGC/GCTTAT 1 -- int10--------
    rs350931541,2
    C--137327864(+) CTTTC-/TTTTTT 1 -- int12Minor allele frequency- T:0.25NA 4
    rs1436839121,2
    --137327895(+) CACTCC/TGTTGC 1 -- int10--------
    rs1472244581,2
    --137327928(+) AATCAC/TGGCTC 1 -- int10--------
    rs94946281,2
    C--137328033(+) gtttcA/Gtattt 1 -- int10--------
    rs7719471,2
    C,A,H--137328112(+) TGCCTT/CGGCCT 1 -- int16Minor allele frequency- C:0.00NA WA 12
    rs1510626991,2
    --137328163(+) GCCACC/TTTTTT 1 -- int10--------
    rs1398218591,2
    --137328242(+) TTTTGC/TTCCAA 1 -- int10--------
    rs1170789011,2
    F--137328317(+) AGAGAG/CCACTT 1 -- int11Minor allele frequency- C:0.03NA 120
    rs1124968201,2
    C,F--137328326(+) TTCTCC/TCAAAT 1 -- int11Minor allele frequency- T:0.02NA 120
    rs7719481,2
    C,F,O,A,H--137328338(-) AATCGT/CATTTG 1 -- int120Minor allele frequency- C:0.30NS NA WA CSA EA 1806
    rs1498014561,2
    --137328426(+) AGCTAC/TGATAA 1 -- int10--------
    rs7719491,2
    C,F,H--137328470(-) AGTACA/CTGTGA 1 -- int110Minor allele frequency- C:0.31NA WA CSA 254
    rs795955391,2
    F--137328514(+) TCATCG/ATGAAA 1 -- int11Minor allele frequency- A:0.07WA 118
    rs358197631,2
    F--137328606(+) AGGTCG/ATGGGC 1 -- int11Minor allele frequency- A:0.08WA 118
    rs7719501,2
    C,F,H--137328608(-) AGGCCC/GACGAC 1 -- int113Minor allele frequency- G:0.15NS EA NA WA CSA 554
    rs1885246631,2
    --137328609(+) TCGTCA/GGCCTC 1 -- int10--------
    rs1467734361,2
    --137328634(+) CTGTTC/TGGAAA 1 -- int10--------
    rs1405368331,2
    --137328937(+) GCAGCA/CAATTA 1 -- int10--------
    rs1810334681,2
    C--137329011(+) ATTCTG/TCTTTA 1 -- int10--------
    rs17440661,2
    C,F,O,A,H--137329034(+) AATAAC/TGCTTT 1 -- int125Minor allele frequency- T:0.16NS EA NA WA CSA 2060
    rs1444733531,2
    --137329035(+) ATAATA/GCTTTG 1 -- int10--------
    rs1836429391,2
    --137329298(+) GGTCTC/TACTAT 1 -- int10--------
    rs1893138361,2
    C--137329504(+) GTGGAC/TACGGG 1 -- int10--------
    rs2006133501,2
    --137329780(+) CACGGC/TGAGGG 2 H R mis10--------
    rs2016281251,2
    C--137329781(+) ACGGCG/AAGGGG 2 /R /C mis11Minor allele frequency- A:0.00EU 1323
    rs94839751,2
    C,F,H--137329854(+) ACCAGC/TGTGTG 2 T syn1 ese314Minor allele frequency- T:0.08NS EA NA WA CSA EU 7346
    rs1822074071,2
    --137329880(+) GGACCA/GCTAGG 2 R W mis10--------
    rs30418901,2
    C--137330023(+) TTTTT-/TT    
       
    /TTTT
    CAGCA
    1 -- int1 trp31NA 2
    rs2008202771,2
    C--137330024(-) TTGCTA/GAAAAA 1 -- int10--------
    rs1151331731,2
    C,F--137330190(+) CAAGTG/CAAAGC 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1872794571,2
    --137330213(+) TGAAGA/TGTACA 1 -- int10--------
    rs1917265931,2
    --137330295(+) TCTGTA/GAAATT 1 -- int10--------
    rs802310681,2
    C--137330406(+) CATTAG/TCTACA 1 -- int10--------
    rs1815726641,2
    C--137330418(+) AGTGGG/TACATG 1 -- int10--------
    rs788120121,2
    C,F--137330432(+) GTATGC/GCCCAT 1 -- int13Minor allele frequency- G:0.01WA EU 1443
    rs1422886481,2
    C,F--137330455(+) TTACCG/ATTCTG 2 /T /M mis12Minor allele frequency- A:0.00NA EU 5869
    rs1430055321,2
    C,F--137330486(+) AGACAC/TGTTAT 2 M V mis12Minor allele frequency- T:0.00NA EU 5873
    rs1466446511,2
    C,F--137330503(+) GATTGG/TAGTAT 2 Y S mis12Minor allele frequency- T:0.00NA EU 5873
    rs2006780571,2
    --137330636(+) TTAAAG/TGGGGA 1 -- int10--------
    rs1413368581,2
    --137330709(+) ACTTGA/GATCAA 1 -- int10--------
    rs558121021,2
    C--137330760(+) TTTTT-/TTTTTT
    /TTTTTTT
    GAGAT
    2 -- int1 cds11NA 2
    rs7719511,2
    C--137330891(+) GTGCCC/TGCCAA 1 -- int18Minor allele frequency- T:0.06NA WA CSA 16
    rs1482173011,2
    --137330935(+) ACGGGA/GTTTCA 1 -- int10--------
    rs1132514301,2
    F--137330948(+) ATGTTG/AGCCAG 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs7719521,2
    C--137330957(+) AGGCTG/TGTCTC 1 -- int112Minor allele frequency- T:0.13NA EA MN WA CSA 450
    rs94028641,2
    C,A--137330970(+) ACTCCT/CGATCC 1 -- int13Minor allele frequency- C:0.25NA WA 240
    rs1858857641,2
    --137331068(+) AGATGC/TCCCAA 1 -- int10--------
    rs1378758341,2
    C--137331095(+) CCTGAC/GATATG 1 -- int10--------
    rs2006145541,2
    --137331120(+) CATCC-/TGAAA 
     CCAACCT
    TGAAA
    1 -- int10--------
    rs1434342471,2
    --137331129(+) ACCAAC/TCTTGA 1 -- int10--------
    rs170659751,2
    C,F,H--137331228(+) TAATAC/TAATCA 1 -- int111Minor allele frequency- T:0.02NA NS EA WA 1172
    rs1389785911,2
    C--137331323(+) GATTAC/GAATGA 1 -- int10--------
    rs1902598831,2
    --137331357(+) TTTATA/CCTAAA 1 -- int10--------
    rs735606511,2
    C--137331386(+) TTCAGG/TCATCG 1 -- int12Minor allele frequency- T:0.09WA 120
    rs1492954691,2
    --137331399(+) GGCCAC/TATGAT 1 -- int10--------
    rs1113856741,2
    C,F--137331424(+) TCCACT/CCTTGC 1 -- int12Minor allele frequency- C:0.02NA 122
    rs7719531,2
    C,F,A,H--137331484(+) TTGTGT/CCCCAA 1 -- int114Minor allele frequency- C:0.19NS EA NA WA CSA 786
    rs3704814141,2
    C--137331594(+) AAATAC/TCATTC 1 -- int10--------
    rs562055701,2
    C--137331642(+) TTGGA-/TTTGTC 1 -- int11Minor allele frequency- T:0.00NA 2
    rs2015940141,2
    --137331645(+) GATTT-/GTCCCA 1 -- int10--------
    rs1825334111,2
    --137331697(+) TTATGA/GAGCAC 1 -- int10--------
    rs1868610061,2
    --137331723(+) TGGCAG/TCCCTG 1 -- int10--------
    rs1909301191,2
    --137331725(+) GCAGCC/GCTGAG 1 -- int10--------
    rs1120891551,2
    F--137331876(+) TAGTGG/TATAAT 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs779112771,2
    F--137332243(+) TGAGAC/TTCAGA 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1840190401,2
    C--137332365(+) CCTGAC/TATGAA 1 -- int10--------
    rs1890034501,2
    C--137332400(+) TAATGG/TCATTA 1 -- int10--------
    rs1999542311,2
    --137332438(+) TCCACC/TTTCAG 2 S G mis10--------
    rs1382622391,2
    F--137332454(+) TTGGAA/GCACTT 2 C syn11Minor allele frequency- G:0.00NA 4550
    rs1422515951,2
    C,F--137332551(+) TATTTC/TTGCAT 2 K R mis12Minor allele frequency- T:0.00NA EU 5727
    rs7719541,2
    C,H--137332745(+) TGCGGC/TGGGCA 1 -- int113Minor allele frequency- T:0.01NA WA CSA EA 377
    rs1843353421,2
    --137332753(+) GCAATC/TTTTTT 1 -- int10--------
    rs1872274601,2
    --137332872(+) GCTACA/CGTGAA 1 -- int10--------
    rs1917424291,2
    --137332906(+) TTCTTC/TTAGTA 1 -- int10--------
    rs1838767771,2
    --137333016(+) TTGACA/GTTCTC 1 -- int10--------
    rs1892823481,2
    C--137333027(+) ATAGCA/TTATAA 1 -- int10--------
    rs7719551,2
    C,F,A--137333067(+) ATACAT/CGAGGC 1 -- int118Minor allele frequency- C:0.17NA EA WA CSA 1077
    rs1484567511,2
    --137333096(+) CTGCAC/TTTTTG 1 -- int10--------
    rs1423185361,2
    C--137333218(+) CTTTTC/TAGGTG 1 -- int10--------
    rs94946291,2
    C,F,A,H--137333308(+) tgggtT/Cacaag 1 -- int15Minor allele frequency- C:0.03NS EA WA 528
    rs119637051,2
    C,F,H--137333358(+) ccaggG/Agaaga 1 -- int110Minor allele frequency- A:0.13NS EA WA NA 1434
    rs1808301341,2
    --137333371(+) TAGGTC/TGCTTG 1 -- int10--------
    rs1857161901,2
    --137333459(+) AAACAC/TGTAAC 1 -- int10--------
    rs715606201,2
    C,F--137333481(+) ATGAAG/AGTGTT 1 -- int13Minor allele frequency- A:0.05NA 124
    rs1906268061,2
    --137333642(+) GCCTGA/CGTATG 1 -- int10--------
    rs1445198431,2
    C--137333700(+) GAGAC-/ATGTGTG 1 -- int10--------
    rs20106141,2
    C,F,A,H--137333718(+) gtaggA/Gatttt 1 -- int127Minor allele frequency- G:0.26NS EA NA WA CSA 2412
    rs667357961,2
    C,F--137333787(+) AAACAA/CAATAA 1 -- int15Minor allele frequency- C:0.19NA EA 246
    rs94028651,2
    C,F,A,H--137333851(+) GACCTG/AGAAAT 1 -- int122Minor allele frequency- A:0.40NS EA NA WA 2764
    rs1463378791,2
    --137333871(+) AGAGGA/GATGAG 1 -- int10--------
    rs9118271,2
    C,F,A,H--137333909(+) GAGTGC/TGTCTT 1 -- int130Minor allele frequency- T:0.24NA MN NS EA WA CSA 2757
    rs780642731,2
    C,F--137334231(+) TAAACT/GTTACC 1 -- int12Minor allele frequency- G:0.03NA 122
    rs13223911,2
    H--137334265(+) ttcatT/Accagt 1 -- int16Minor allele frequency- A:0.01EA NS 596
    rs94839761,2
    C,F,A,H--137334347(+) GAGTCC/TTGAAT 1 -- int124Minor allele frequency- T:0.18NS EA NA WA CSA 2766
    rs1817758571,2
    --137334375(+) TGCCAG/TTGCCT 1 -- int10--------
    rs1442157181,2
    --137334469(+) GCTCTC/TTACAA 1 -- int10--------
    rs1861368841,2
    --137334484(+) TTCAAC/TAAAAT 1 -- int10--------
    rs1129196411,2
    C--137334688(+) TAAGGG/AATCCA 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1813541341,2
    --137334751(+) CCTGAC/TGCCAA 1 -- int10--------
    rs13223921,2
    C,F,A,H--137334786(+) CTATTA/TTTTTG 1 -- int115Minor allele frequency- T:0.40NA NS EA WA 926
    rs13223931,2
    C,F,O,A,H--137334946(+) CTGAGA/CTTGGA 1 -- int123Minor allele frequency- C:0.29NA EA MN NS WA 4290
    rs69173791,2
    C,F,H--137335030(+) ACATCG/ACAAGC 1 -- int16Minor allele frequency- A:0.02NS EA NA WA 540
    rs1466340251,2
    --137335250(+) CACTGA/GCTCCT 1 -- int10--------
    rs1411184361,2
    C--137335289(+) TTCTAA/GATAAA 1 -- int10--------
    rs13223941,2
    C,F,A,H--137335607(+) AGTCAG/ATTCAA 1 -- int1108Minor allele frequency- A:0.26EA NS PA EU CA WA NA 7004
    rs1864332251,2
    --137335836(+) TATAGC/TTCCCC 1 -- int10--------
    rs1464903481,2
    C--137335838(+) TAGTT-/CCCCCC 1 -- int10--------
    rs1161835221,2
    F--137335953(+) TCCATG/ACATGC 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1498538051,2
    C--137335993(+) TCTTTC/TGGGTT 1 -- int10--------
    rs1909291781,2
    --137336041(+) TTAGTG/TCTCCA 1 -- int10--------
    rs1457883831,2
    --137336433(+) TCCAGA/CATTTT 1 -- int10--------
    rs1828301561,2
    --137336450(+) CTCTGA/CACACT 1 -- int10--------
    rs4124751,2
    C,F,A,H--137336840(+) TCCAGG/ACTGGA 1 -- int110Minor allele frequency- A:0.25NA WA CSA EA 372
    rs608227601,2
    C,F--137336841(+) CCAGAC/TTGGAG 1 -- int12Minor allele frequency- T:0.25WA 120
    rs69400271,2
    C,F--137336954(+) atgacC/Tggcta 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1489865931,2
    C--137337002(+) TTGCAC/TAGGTT 1 -- int10--------
    rs1857576801,2
    --137337026(+) TGAGCG/TCATGC 1 -- int10--------
    rs3817831,2
    C,F,O,A,H--137337096(-) AGAGCG/ATTGGC 1 -- int122Minor allele frequency- A:0.33NS EA NA WA CSA 1978
    rs4096691,2
    C,F,A,H--137337215(+) GATGTT/CGTAGC 1 -- int114Minor allele frequency- C:0.22NS EA NA WA CSA 792
    rs1923226321,2
    --137337230(+) CTGGGC/TTGCCT 1 -- int10--------
    rs4498521,2
    C,F--137337255(+) CCTCCA/C/GTTTCC 1 -- int1 trp310EA NA WA CSA 1844
    rs4137981,2
    C,F,A,H--137337354(+) GTTTCG/ACCACC 1 -- int114Minor allele frequency- A:0.22NS EA NA WA CSA 788
    rs1831074091,2
    --137337595(+) GTTCCC/TAGTTT 1 -- int10--------
    rs1874464491,2
    --137337630(+) TTTGTC/TTCTCT 1 -- int10--------
    rs3839901,2
    C,F,O,A--137337698(+) GGCCAG/AATGAA 1 -- int114Minor allele frequency- A:0.15NA EA WA CSA 759
    rs9815351,2
    C,F,O,A,H--137337897(+) TGCCTC/TGCCTG 1 -- int120Minor allele frequency- T:0.34NA EA NS CSA 1229
    rs4410111,2
    C,F,O,A,H--137337965(+) ACATCA/CAGAAA 1 -- int118Minor allele frequency- C:0.22NA NS EA WA CSA 934
    rs1124564841,2
    C--137338074(+) TTTGTC/AAGCTA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1919966431,2
    C--137338202(+) GGTGAT/CGTTTG 2 /I /V mis11Minor allele frequency- C:0.00EU 1319
    rs1485186761,2
    C,F--137338225(+) AACCAC/ACAGAG 2 /G /V mis12Minor allele frequency- A:0.00NA EU 5869
    rs2018012931,2
    --137338271(+) AGGTCC/TTAGTA 1 -- int10--------
    rs4332431,2
    C,F,A,H--137338276(+) TTAGTG/AGCAGA 1 -- int125Minor allele frequency- A:0.20NS EA NA WA CSA EU 3509
    rs602784411,2
    C,F--137338341(+) GCCTTC/ACAGTA 1 -- int14Minor allele frequency- A:0.17WA CSA NA 241
    rs4513711,2
    C,F,A,H--137338352(+) TGCATT/GCCCTA 1 -- int110Minor allele frequency- G:0.37NA WA CSA 256
    rs4426631,2
    C,F,A,H--137338357(+) GCCCTG/ATGTAA 1 -- int111Minor allele frequency- A:0.24NA WA CSA EA 376
    rs780488331,2
    F--137338443(+) TTCCCG/CAGTTG 1 -- int11Minor allele frequency- C:0.02EA 120
    rs3659271,2
    C,F,A,H--137338447(+) CGAGTA/TGCTAT 1 -- int114Minor allele frequency- T:0.26NS EA NA WA CSA 672
    rs3841121,2
    C,F,A,H--137338487(+) CCATGC/TTGAGA 1 -- int119Minor allele frequency- T:0.33NS EA NA WA CSA 1846
    rs1826517861,2
    --137338504(+) ACGAAA/GAGAGG 1 -- int10--------
    rs1882251951,2
    C--137338506(+) GAAGAC/GAGGCT 1 -- int10--------
    rs569333971,2
    C,F--137338523(+) TCCTGG/CTGTCC 1 -- int11Minor allele frequency- C:0.50WA 2
    rs1419578941,2
    C--137338633(+) TGAGAC/TCAGCA 1 -- int10--------
    rs1925107171,2
    C--137338756(+) AAAACA/CATCTC 1 -- int10--------
    rs11678521,2
    C,F,A,H--137338848(+) ACTAAT/AGAATA 1 -- int17Minor allele frequency- A:0.46NA WA EA 366
    rs1844924941,2
    --137338965(+) GATTAA/GTTTAC 1 -- int10--------
    rs1458112101,2
    C--137339156(+) AAGCAC/TGGAGT 1 -- int10--------
    rs751573521,2
    F--137339157(+) AGCACG/AGAGTG 1 -- int11Minor allele frequency- A:0.06EA 120
    rs1890167891,2
    --137339236(+) TTGAAA/GAATAT 1 -- int10--------
    rs1449224271,2
    C--137339267(+) CAAAC-/TTAGGAA 1 -- int10--------
    rs1141179601,2
    F--137339295(+) TCACTG/CATGGC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs4380981,2
    C,F,O,A,H--137339320(+) CTAAGT/GATCAT 1 -- int116Minor allele frequency- G:0.25NA NS EA WA CSA 814
    rs3712391,2
    C,F,A,H--137339389(-) TTAACC/TAAGGA 1 -- int114Minor allele frequency- T:0.22NS EA NA WA CSA 790
    rs343989801,2
    C,F--137339461(+) TTAGAA/GTTAAA 1 -- int15Minor allele frequency- G:0.07NA WA 244
    rs1150431841,2
    F--137339569(+) TTTTAA/TCCTTG 1 -- int11Minor allele frequency- T:0.01WA 118
    rs358138911,2
    F--137339651(+) TGTGCG/ATGTGT 1 -- int13Minor allele frequency- A:0.06NA 124
    rs38421151,2
    C--137339686(+) TGTGT-/GT/GTGT/
    GTGTGTGTGT
    TAGGG
    1 -- int11NA 2
    rs1925729031,2
    --137339748(+) TTCTTA/GTAATT 1 -- int10--------
    rs1848057071,2
    --137339811(+) GAGTGA/GATATT 1 -- int10--------
    rs1891910911,2
    --137339881(+) TGAAGA/CCAAAA 1 -- int10--------
    rs13223981,2
    C,F,A,H--137339887(+) CAAAAC/TAGAAC 1 -- int116Minor allele frequency- T:0.18EA NS NA WA CSA 967
    rs13589381,2
    C,F,O,A,H--137339935(+) TCTTCT/CAAAAT 1 -- int116Minor allele frequency- C:0.22NS EA NA WA CSA 931
    rs1386708561,2
    C--137340038(+) TGGTTA/GGCATC 1 -- int10--------
    rs1815519671,2
    --137340075(+) TTATAA/CTATCA 1 -- int10--------
    rs1865187501,2
    --137340137(+) GAACAC/TTTTGG 1 -- int10--------
    rs339609341,2
    C--137340268(+) TTATC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1413007041,2
    C--137340315(+) CTGGAA/GTGCAG 1 -- int10--------
    rs1508043921,2
    C--137340557(+) CACCGC/TGCCCA 1 -- int10--------
    rs11848601,2
    C,F,O,A--137340604(+) CAGAGT/CTCTCA 1 -- int111Minor allele frequency- C:0.44NA WA EA 510
    rs1380176721,2
    --137340687(+) TTTAAC/TTTAGT 1 -- int10--------
    rs791235961,2
    F--137340935(+) TAATGT/CTCTTA 1 -- int11Minor allele frequency- C:0.01NA 120
    rs117577341,2
    C,F,H--137340979(+) CATTAT/AAAATG 1 -- int110Minor allele frequency- A:0.19NS EA NA 1080
    rs117552721,2
    C,F,H--137341012(+) CTGCAC/TGTCTA 1 -- int115Minor allele frequency- T:0.17NS EA NA 2042
    rs765727331,2
    C,F--137341289(+) GCCCAT/GGTGGC 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1495200791,2
    C--137341302(+) AGTAAC/TTGAGG 1 -- int10--------
    rs121109021,2
    C,F--137341375(+) gaagtG/Agatcc 1 -- int15Minor allele frequency- A:0.07NA WA 244
    rs2764761,2
    C,F,A,H--137341383(+) TCCTCT/CGACCC 1 -- int113Minor allele frequency- C:0.13NS EA NA WA CSA 672
    rs1463257051,2
    C--137341402(+) CCTTCA/GGATGA 1 -- int10--------
    rs1155925581,2
    C,F--137341528(+) TTGTTT/CAAAGC 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1396488451,2
    --137341543(+) AAGTGC/TAAGGT 1 -- int10--------
    rs58803261,2
    C--137341641(+) AAAAA-/CCCCTC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs742993431,2
    C--137341641(+) AAAAAA/CCCCTC 1 -- int10--------
    rs457581,2
    C,F,O,A,H--137341683(+) CTTAAT/CAATTT 1 -- int119Minor allele frequency- C:0.23NA EA NS WA 1176
    rs1898458391,2
    --137341730(+) TATGAA/GAAAAA 1 -- int10--------
    rs1811196651,2
    --137341731(+) ATGAAA/TAAAAT 1 -- int10--------
    rs69271211,2
    C,F,A,H--137341749(+) TACCCG/AAGGAG 1 -- int1 trp36Minor allele frequency- A:0.13NS EA WA 524
    rs1861395231,2
    --137341852(+) CTCATG/TGCAAA 1 -- int10--------
    rs2764771,2
    C,F,A--137341974(+) TGCAGG/TTTCTT 1 -- int1 trp312