Aliases for IL20RA Gene
External Ids for IL20RA Gene
Previous GeneCards Identifiers for IL20RA Gene
This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for IL20RA Gene
IL20RA (Interleukin 20 Receptor Subunit Alpha) is a Protein Coding gene. Diseases associated with IL20RA include Psoriasis. Among its related pathways are Akt Signaling and Jak-STAT signaling pathway (KEGG). GO annotations related to this gene include cytokine receptor activity and interleukin-20 binding. An important paralog of this gene is IL22RA1.
UniProtKB/Swiss-Prot for IL20RA Gene
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.