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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IL20RA Gene

protein-coding   GIFtS: 57
GCID: GC06M137321

interleukin 20 receptor, alpha

 Explore 7 diseases affiliated with
IL20RA via our new
 Human Malady Compendium 
Biological research products
for IL20RA
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Interleukin 20 Receptor, Alpha1 2     IL-20RA2 3
IL-20R11 2 3     IL-20 Receptor Subunit Alpha2 3
ZCYTOR71 2     Class II Cytokine Receptor ZCYTOR72
Cytokine Receptor Class-II Member 82 3     Interleukin-20 Receptor I2
Cytokine Receptor Family 2 Member 82 3     Interleukin-20 Receptor Subunit Alpha2
CRF2-82 3     ZcytoR73
IL-20R-Alpha1     

External Ids:    HGNC: 60031   Entrez Gene: 538322   Ensembl: ENSG000000164027   OMIM: 6056205   UniProtKB: Q9UHF43   

Export aliases for IL20RA gene to outside databases

Previous GC identifers: GC06M136944 GC06M137168 GC06M137301 GC06M137362 GC06M134884


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL20RA:
The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal
function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20
receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be
upregulated in Psoriasis. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26

Gene Wiki entry for IL20RA (Interleukin 20 receptor, alpha subunit)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IL20RA gene promoter:
         AREB6   STAT1   POU2F1   POU2F1a   STAT1beta   Cart-1   STAT3   Nkx2-5   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL20RA promoter sequence
   Search SABiosciences Chromatin IP Primers for IL20RA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL20RA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.3   Ensembl cytogenetic band:  6q23.3   HGNC cytogenetic band: 6q23.3

IL20RA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL20RA gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M137321:  view genomic region     (about GC identifiers)

Start:
137,321,108 bp from pter      End:
137,366,298 bp from pter
Size:
45,191 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4 (See protein sequence)
Recommended Name: Interleukin-20 receptor subunit alpha precursor  
Size: 553 amino acids; 62485 Da
Subunit: Heterodimer with IL20RB and heterodimer with IL10RB
Subcellular location: Membrane; Single-pass type I membrane protein (By similarity)
1 PDB 3D structure from and Proteopedia for IL20RA:
4DOH (3D)    
Secondary accessions: Q14CW2 Q6UWA9 Q96SH8
Alternative splicing: 2 isoforms:  Q9UHF4-1   Q9UHF4-2   

Explore the universe of human proteins at neXtProt for IL20RA: NX_Q9UHF4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UHF4

  • IL20RA Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055247.2  
    ENSEMBL proteins: 
     ENSP00000314976   ENSP00000356720   ENSP00000437843   ENSP00000356722  

    Human Recombinant Protein Products: 
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    Novus Biologicals IL20RA Lysate
    Sino Biological Recombinant Protein for IL20RA
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    IL20RA for ontologies           About GeneDecksing



    IL20RA Antibody Products: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IL20RA for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015713 Interleukin-20_rcpt_asu
     IPR003961 Fibronectin_type3
     IPR015373 Interferon_alpha/beta_rcpt_bsu
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry Q9UHF4

    ProtoNet protein and cluster: Q9UHF4

    1 Blocks protein family: IPB001187 Tissue factor

    UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
    Similarity: Belongs to the type II cytokine receptor family
    Similarity: Contains 2 fibronectin type-III domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
    Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate IL20RA (see all 13):
    hsa-miR-3163 hsa-miR-550a hsa-miR-4288 hsa-miR-589* hsa-miR-632 hsa-miR-346 hsa-miR-944 hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidIL20RA 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IL20RA (see all 7)
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL20RA

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RA

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----


    IL20RA for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for IL20RA:
     Increased cell number in G1, s 

    Animal Models:
         Mouse knock-out Il20ratm1.1Misc for IL20RA
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Il20ra):
     cellular  hematopoietic system  immune system  skeleton 

    IL20RA for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    2PEDF Induced Signaling
    STAT3 Pathway0.47
    Cytokine-cytokine receptor interaction0.26
    3Jak-STAT signaling pathway
    Jak-STAT signaling pathway1.00
    4TGF-Beta Pathway
    MAPK Family Pathway0.60
    5PAK Pathway
    Antioxidant Action of Vitamin-C0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IL20RA (see all 7)
        STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    p38 Signaling
    Akt Signaling


    2         Kegg Pathways  (Kegg details for IL20RA):
        Cytokine-cytokine receptor interaction
    Jak-STAT signaling pathway


    IL20RA for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL20RA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/20 Interacting proteins for IL20RA (Q9UHF43 ENSP000003149764) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IL19Q9UHD03, ENSP000003430004I2D: score=1 STRING: ENSP00000343000
    IL20Q9NYY13, ENSP000003560634I2D: score=1 STRING: ENSP00000356063
    IL24Q130073, ENSP000002949844I2D: score=1 STRING: ENSP00000294984
    IL26Q9NPH93I2D: score=1 
    MLH1P406923I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IL20RA
    Search CenterWatch for drugs/clinical trials and news about IL20RA / I20RA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IL20RA gene: 
    NM_014432.2  

    Unigene Cluster for IL20RA:

    Interleukin 20 receptor, alpha
    Hs.445868  [show with all ESTs]
    Unigene Representative Sequence: NM_014432
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000316649(uc003qhi.3 uc011edl.2) ENST00000468393 ENST00000367746
    ENST00000461799 ENST00000460306 ENST00000541547 ENST00000367748(uc003qhj.3 uc003qhk.3 uc010kgy.1)


    miRNA
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    hsa-miR-3163 hsa-miR-550a hsa-miR-4288 hsa-miR-589* hsa-miR-632 hsa-miR-346 hsa-miR-944 hsa-miR-340
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    Inhib. RNA
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    OriGene siRNA: IL20RA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL20RA
    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL20RA
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL20RA

    Additional cDNA sequence: 

    AF184971.1 AJ420490.1 AK098312.1 AK297121.1 AK307072.1 AK315293.1 AY358883.1 BC113574.1 
    BC113602.1 

    7 DOTS entries:

    DT.212820  DT.100748883  DT.99935447  DT.95357173  DT.91967433  DT.75169701  DT.97808767 

    24/66 AceView cDNA sequences (see all 66):

    BQ185521 CB128408 AI350971 BM683620 AA299011 NM_014432 BM674665 BU579846 
    AA632915 AI308941 AA514541 AA583432 AI912054 AY358883 AI381033 AI675877 
    BU580093 CK299400 BP374751 BG743223 AI659083 AW340967 BE219979 BF433364 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for IL20RA (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b · 10c
    SP1:                          -     -     -     -     -                             -     -                                       
    SP2:                          -     -     -     -     -           -                 -     -                                       
    SP3:                          -     -     -     -     -                                                                           
    SP4:                                      -     -     -           -     -           -     -                                       
    SP5:                          -     -                                                                                             


    ECgene alternative splicing isoforms for IL20RA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IL20RA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAGGTCTCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See IL20RA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IL20RA

    SOURCE GeneReport for Unigene cluster: Hs.445868

    UniProtKB/Swiss-Prot: I20RA_HUMAN, Q9UHF4
    Tissue specificity: Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed
    in psoriatic skin

        SABiosciences Expression via Pathway-Focused PCR Arrays including IL20RA: 
              Interferons & Receptors in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL20RA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IL20RA gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves IL20RA1 interleukin 20 receptor, alpha 55.35(n)
    42.78(a)
      421686  XM_419723.3  XP_419723.1 
    zebrafish
    (Danio rerio)
    Actinopterygii crfb81 cytokine receptor family member b8 44.08(n)
    31.13(a)
      556728  NM_001079676.2  NP_001073144.2 


    ENSEMBL Gene Tree for IL20RA (if available)
    TreeFam Gene Tree for IL20RA (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IL20RA gene
    IL22RA22  IL22RA12  

    IL20RA for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/832 NCBI SNPs in IL20RA are shown (see all 832    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1384243181,2
    C,F,other137323071(+) ATGTTC/TCTTGT 2 E G mis12Minor allele frequency- T:0.00NA EU 5871
    rs1409450881,2
    --137320703(+) TAAAAC/GCAACT 1 -- ds50010--------
    rs1831276921,2
    --137320723(+) ATTCCC/TCTTTT 1 -- ds50010--------
    rs9274431,2
    C,F,O,A,H,--137320867(+) TATGTT/CTAAAT 1 -- ds500125Minor allele frequency- C:0.27MN NS EA NA WA CSA 2344
    rs1868770401,2
    --137320973(+) TAAGTA/GCCTTC 1 -- ds50010--------
    rs9274441,2
    C,F,A,H,--137320996(+) CTTTTT/AATCCT 1 -- ds500113Minor allele frequency- A:0.19MN NS EA NA WA CSA 854
    rs788946781,2
    F,--137321009(+) AAACAG/ACCCTA 1 -- ds50011Minor allele frequency- A:0.06WA 118
    rs1913376821,2
    --137321065(+) TATTAA/GGTACT 1 -- ds50010--------
    rs1389619111,2
    --137321298(+) TGAAAC/TTGTTT 1 -- ut310--------
    rs755232021,2
    C,F,--137321322(+) ATCACG/AAAAGG 1 -- ut311Minor allele frequency- A:0.06WA 118

    HapMap Linkage Disequilibrium report for IL20RA (137321108 - 137366298 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for IL20RA
         1 CNV: 6513
    Human Gene Mutation Database (HGMD): IL20RA

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL20RA
    DNA2.0 Custom Variant and Variant Library Synthesis for IL20RA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IL20RA for disorders           About GeneDecksing

    OMIM gene information: 605620    OMIM disorders: --

    7 diseases for IL20RA:    About MalaCards
    psoriasis    cblc    vitiligo    hepatitis b
    liver cancer    atherosclerosis    hepatitis

    1 disease from the University of Copenhagen DISEASES database for IL20RA:
    Psoriasis

    1 Novoseek disease relationship for IL20RA gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psoriasis 56.9 5 18480827 (4)

    Human Genome Epidemiology (HuGE) Navigator: IL20RA (8 documents)

    Export disorders for IL20RA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IL20RA gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with IL20RA)
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    1. Interleukin 20: discovery, receptor identification, and role in epidermal function. (PubMed id 11163236)1, 2, 3 Blumberg H.... Chandrasekher Y.A. (2001)
    2. IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. (PubMed id 14764663)1, 2, 9 Sheikh F.... Kotenko S.V. (2004)
    3. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    4. Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. (PubMed id 14580208)1, 2 Pletnev S.... Zdanov A. (2003)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. (PubMed id 12351624)1, 2 Parrish-Novak J.... Chandrasekher Y.A. (2002)
    8. STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. (PubMed id 11564763)1, 2 Dumoutier L.... Renauld J.-C. (2001)
    9. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. (PubMed id 10875937)1, 3 Xie M.H....Gurney A.L. (2000)
    10. Association analysis of IL20RA and IL20RB genes in psoriasis. (PubMed id 18480827)1, 9 Kingo K....Koks S. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53832 HGNC: 6003 AceView: IL20RA Ensembl:ENSG00000016402 euGenes: HUgn53832
    ECgene: IL20RA Kegg: 53832 H-InvDB: IL20RA

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IL20RA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IL20RA gene:
    Search GeneIP for patents involving IL20RA

    GeneCards and IP:
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