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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

IL1RL2 Gene

protein-coding GIFtS: 54
GCID: GC02P102803

interleukin 1 receptor-like 2

Explore 8 diseases affiliated with
IL1RL2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Interleukin 1 Receptor-Like 2¹ ²		IL-1Rrp2² ³
IL1RRP2¹ ² ³ ⁵		IL-36R²
IL1R-Rp2¹		IL-1 Receptor-Related Protein 2²
Interleukin-1 Receptor-Related Protein 2² ³		Interleukin-1 Receptor-Like 2²

External Ids:	HGNC: 5999¹	Entrez Gene: 8808²	Ensembl: ENSG00000115598⁷	OMIM: 604512⁵	UniProtKB: Q9HB29³

Export aliases for IL1RL2 gene to outside databases

Previous GC identifers: GC02P100667 GC02P101256 GC02P102408 GC02P102424 GC02P102261 GC02P096567

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL1RL2:

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene

expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with

high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I

(IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor

1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. (provided by RefSeq, Jul

2008)

UniProtKB/Swiss-Prot: ILRL2_HUMAN, Q9HB29

Function: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of

NF-kappa-B

Gene Wiki entry for IL1RL2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022171.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IL1RL2 gene promoter:
TBP Gfi-1 GATA-1 RORalpha1 CREB PPAR-gamma1 POU2F1 POU2F1a deltaCREB PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IL1RL2 promoter sequence

Search SABiosciences Chromatin IP Primers for IL1RL2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL1RL2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12 Ensembl cytogenetic band: 2q12.1 HGNC cytogenetic band: 2q12

IL1RL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL1RL2 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P102803: view genomic region (about GC identifiers)

Start:	102,803,433 bp from pter	End:	102,856,462 bp from pter
Size:	53,030 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ILRL2_HUMAN, Q9HB29 (See protein sequence)

Recommended Name: Interleukin-1 receptor-like 2 precursor

Size: 575 amino acids; 65405 Da

Subunit: Does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta

Subcellular location: Membrane; Single-pass type I membrane protein

Sequence caution: Sequence=AAB53237.1; Type=Frameshift; Positions=556;

Secondary accessions: Q13525 Q45H74 Q53TU8 Q587I8

Explore the universe of human proteins at neXtProt for IL1RL2: NX_Q9HB29

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HB29

IL1RL2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_003845.2

ENSEMBL proteins:

ENSP00000264257 ENSP00000387611 ENSP00000413348 ENSP00000442184

Human Recombinant Protein Products for IL1RL2:

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	Uscn Proteins for IL1RL2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005887	integral to plasma membrane	TAS	1833184
GO:0016021	integral to membrane	--	--

IL1RL2 for ontologies About GeneDecksing

IL1RL2 Antibody Products:

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	Uscn ELISAs and CLIAs for IL1RL2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IL1RL2 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR015621 IL1-receptor_fam

IPR007110 Ig-like_dom

IPR004076 IL1R_rcpt

IPR003599 Ig_sub

IPR000157 TIR_dom

Graphical View of Domain Structure for InterPro Entry Q9HB29

ProtoNet protein and cluster: Q9HB29

3 Blocks protein families:

IPB000157 TIR domain

IPB003599 Immunoglobulin subtype

IPB004075 Interleukin-1 receptor type I family signature

UniProtKB/Swiss-Prot: ILRL2_HUMAN, Q9HB29

Similarity: Belongs to the interleukin-1 receptor family

Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains

Similarity: Contains 1 TIR domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ILRL2_HUMAN, Q9HB29

Function: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of

NF-kappa-B

Genatlas biochemistry entry for IL1RL2:

interleukin 1 receptor related protein 2,not binding IL1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004908	interleukin-1 receptor activity	TAS	1833184
GO:0004909	interleukin-1, Type I, activating receptor activity	IEA	--

IL1RL2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for IL1RL2:

Synthetic lethal with Ras

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Il1rl2):

integument

normal

IL1RL2 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for IL1RL2

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL1RL2
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL1RL2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL1RL2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL1RL2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for IL1RL2

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for IL1RL2 (Q9HB29³ ENSP00000264257⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IL18	Q14116³, ENSP00000280357⁴	I2D: score=1 STRING: ENSP00000280357
IL1RN	ENSP00000259206⁴	STRING: ENSP00000259206
IL1A	ENSP00000263339⁴	STRING: ENSP00000263339
MYD88	ENSP00000379625⁴	STRING: ENSP00000379625

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006968	cellular defense response	TAS	8332913
GO:0007165	signal transduction	TAS	1833184
GO:0045087	innate immune response	IEA	--

IL1RL2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IL1RL2
Search CenterWatch for drugs/clinical trials and news about IL1RL2 / ILRL2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IL1RL2 gene:

NM_003854.2

Unigene Cluster for IL1RL2:

Interleukin 1 receptor-like 2

Hs.659863 [show with all ESTs]

Unigene Representative Sequence: AF284434

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000264257(uc002tbs.3 uc002tbt.3) ENST00000481806 ENST00000421464

ENST00000441515 ENST00000539491

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IL1RL2
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: IL1RL2 (NM_003854)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL1RL2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL1RL2

Additional cDNA sequence:

AF284434.1 AK315334.1 BC107064.2 U49065.1

2 DOTS entries:

DT.40120316 DT.86843818

8 AceView cDNA sequences:

CA448166 NM_003854 AF284434 BG677958 U49065 AW991351 AW369406 AW747802

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for IL1RL2 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b
SP1:
SP2:							-		-

ECgene alternative splicing isoforms for IL1RL2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IL1RL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTCCTCATT

About this image

IL1RL2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Epicardium

Skeletal Muscle

Mandibular Arch Muscles

Mononuclear Myocytes

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See IL1RL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IL1RL2

SOURCE GeneReport for Unigene cluster: Hs.659863

SABiosciences Expression via Pathway-Focused PCR Array including IL1RL2:

Inflammatory Response & Autoimmunity 384HT in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL1RL2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for IL1RL2 gene from 3/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	IL1RL2¹	interleukin 1 receptor-like 2	54.56(n) 39.74(a)		418716 XM_416915.3 XP_416915.3
lizard (Anolis carolinensis)	Reptilia	IL1R1⁶	--	39(a)	1 → many	GL343243.1(1719891-1732131)
zebrafish (Danio rerio)	Actinopterygii	LOC799279¹	interleukin-1 receptor-like 2-like	47.63(n) 34.63(a)		799279 XM_001339618.4 XP_001339654.4

ENSEMBL Gene Tree for IL1RL2 (if available)
TreeFam Gene Tree for IL1RL2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for IL1RL2 gene

IL1R2² IL1RAPL2² IL1RAP² IL1RL1² IL1RAPL1² IL18RAP² IL18R1² IL1R1²

SIGIRR²

1 SIMAP similar gene for IL1RL2 using alignment to 3 protein entries: ILRL2_HUMAN (see all proteins):

IL1R1

IL1RL2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs1030021^1,2	C,F,A,H	--	102801478(-)	`TTTGCT/GGCTCT`	1	--	us2k¹		21		NS EA NA CSA WA	2516
rs187806260^1,2		--	102801494(+)	`CAAAAC/TTTAAA`	1	--	us2k¹		0	--	--	--	--
rs13003489^1,2	C	--	102801502(+)	`AAAAGT/CCTGAC`	1	--	us2k¹ tfbs³		4		NA WA	242
rs191543717^1,2		--	102801572(+)	`CTATGA/GAAAAA`	1	--	us2k¹		0	--	--	--	--
rs34702050^1,2	C,F	--	102801619(+)	`ACCCAA/GTGATT`	1	--	us2k¹		6		NS NA WA CSA	218
rs144217462^1,2		--	102801755(+)	`ATGAAC/TACATT`	1	--	us2k¹		0	--	--	--	--
rs145305012^1,2	C	--	102801827(+)	`TTTAA-/TTGCTA`	1	--	us2k¹		0	--	--	--	--
rs10181869^1,2	C,F,H	--	102801852(+)	`GGAATC/AAGTTC`	1	--	us2k¹		17		NS EA NA CSA WA	1340
rs183877892^1,2		--	102801866(+)	`CTTCAA/GAGCCA`	1	--	us2k¹		0	--	--	--	--
rs188539530^1,2		--	102801906(+)	`CATTTA/GGCATA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for IL1RL2 (102803433 - 102856462 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IL1RL2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL1RL2

DNA2.0 Custom Variant and Variant Library Synthesis for IL1RL2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

IL1RL2 for disorders           About GeneDecksing

OMIM gene information: 604512    OMIM disorders: --

8 diseases for IL1RL2:    About MalaCards

temporal lobe epilepsy chronic lymphocytic leukemia lymphocytic leukemia celiac disease

hepatitis b osteoarthritis leukemia hepatitis

Human Genome Epidemiology (HuGE) Navigator: IL1RL2 (8 documents)

Export disorders for IL1RL2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for IL1RL2 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with IL1RL2)

Utopia: connect your pdf to the dynamic
world of online information

Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL1R-rp2). (PubMed id 8898719)^{1, 2, 3, 9} Lovenberg T.W.... Maki R.A. (1996)
Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. (PubMed id 11466363)^{1, 2, 3, 9} Debets R....Kastelein R.A. (2001)
Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q. (PubMed id 10191101)^{1, 3, 9} Dale M. and Nicklin M.J. (1999)
Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling. (PubMed id 10882729)^{1, 2} Born T.L....Sims J.E. (2000)
Association between interleukin 1 gene cluster polymo rphisms and bilateral distal interphalangeal osteoarthritis. (PubMed id 19684156)^{1, 9} Solovieva S....Leino-Arjas P. (2009)
Expression of IL-1Rrp2 by human myelomonocytic cells i s unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9. (PubMed id 22144259)¹ Mutamba S....Foster N. (2012)
IL-38 binds to the IL-36 receptor and has biological e ffects on immune cells similar to IL-36 receptor antagonist. (PubMed id 22315422)¹ van de Veerdonk F.L....Dinarello C.A. (2012)
IL-36R ligands are potent regulators of dendritic and T cells. (PubMed id 21860022)¹ Vigne S....Gabay C. (2011)
New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (2010)
Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)¹ Dubois P.C....van Heel D.A. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8808	HGNC: 5999	AceView: IL1RL2	Ensembl:ENSG00000115598	euGenes: HUgn8808
ECgene: IL1RL2	H-InvDB: IL1RL2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for IL1RL2	Pharmacogenomics, SNPs, Pathways
SeattleSNPs	http://pga.gs.washington.edu/data/il1rl2/

Intellectual Property for IL1RL2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for IL1RL2 gene:
Search GeneIP for patents involving IL1RL2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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IL1RL2 Gene

interleukin 1 receptor-like 2

Aliases
for IL1RL2 gene

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IL1RL2 Gene

interleukin 1 receptor-like 2

Aliasesfor IL1RL2 gene

Summariesfor IL1RL2 gene

Genomic Viewsfor IL1RL2 gene

Proteinsfor IL1RL2 gene

Protein Domains /Familiesfor IL1RL2 gene

Functionfor IL1RL2 gene

Pathways & Interactionsfor IL1RL2 gene

Drugs & Compoundsfor IL1RL2 gene

Transcriptsfor IL1RL2 gene

Expression for IL1RL2 gene

Orthologsfor IL1RL2 gene

Paralogsfor IL1RL2 gene

Genomic Variantsfor IL1RL2 gene

Disorders / Diseasesfor IL1RL2 gene

Publicationsfor IL1RL2 gene

External Searches for IL1RL2 gene

Genome Databases showing IL1RL2 gene

Other Databases showing IL1RL2 gene

Specialized Databases showing IL1RL2 gene

Intellectual Propertyfor IL1RL2 gene

Productsfor IL1RL2 gene

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Aliases
for IL1RL2 gene

Summaries
for IL1RL2 gene

Genomic Views
for IL1RL2 gene

Proteins
for IL1RL2 gene

Protein Domains /
Families
for IL1RL2 gene

Function
for IL1RL2 gene

Pathways & Interactions
for IL1RL2 gene

Drugs & Compounds
for IL1RL2 gene

Transcripts
for IL1RL2 gene

Expression
for IL1RL2 gene

Orthologs
for IL1RL2 gene

Paralogs
for IL1RL2 gene

Genomic Variants
for IL1RL2 gene

Disorders / Diseases
for IL1RL2 gene

Publications
for IL1RL2 gene

Intellectual Property
for IL1RL2 gene

Products
for IL1RL2 gene