Aliases for IL1R2 Gene
Aliases for IL1R2 Gene
External Ids for IL1R2 Gene
- HGNC: 5994
- Entrez Gene: 7850
- Ensembl: ENSG00000115590
- OMIM: 147811
- UniProtKB: P27930
Previous HGNC Symbols for IL1R2 Gene
- IL1RB
Previous GeneCards Identifiers for IL1R2 Gene
- GC02P100479
- GC02P101068
- GC02P102212
- GC02P102229
- GC02P102066
- GC02P101974
- GC02P102608
- GC02P096372
Summaries for IL1R2 Gene
-
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
GeneCards Summary for IL1R2 Gene
IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Joint Disorders. Among its related pathways are IL-1 signaling pathway and IL-2 Pathway. GO annotations related to this gene include interleukin-1 receptor activity and interleukin-1, Type II, blocking receptor activity. An important paralog of this gene is IL1R1.
UniProtKB/Swiss-Prot for IL1R2 Gene
-
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
-
Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IL1R2 Gene
Genomics for IL1R2 Gene
Regulatory Elements for IL1R2 Gene
Enhancers for IL1R2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around IL1R2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the IL1R2 gene promoter:
Regulatory Element Products
Genomic Location for IL1R2 Gene
- Chromosome:
- 2
- Start:
- 101,991,816 bp from pter
- End:
- 102,028,544 bp from pter
- Size:
- 36,729 bases
- Orientation:
- Plus strand
Genomic View for IL1R2 Gene
Genes around IL1R2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q11.2 by Ensembl
- 2q11.2 by Entrez Gene
- 2q11.2 by HGNC
IL1R2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IL1R2 Gene
Proteins for IL1R2 Gene
-
Protein details for IL1R2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P27930-IL1R2_HUMAN
- Recommended name:
- Interleukin-1 receptor type 2
- Protein Accession:
- P27930
- D3DVJ5
- Q6LCE6
- Q9UE68
Protein attributes for IL1R2 Gene
- Size:
- 398 amino acids
- Molecular mass:
- 45421 Da
- Quaternary structure:
-
- Associates with IL1RAP to form a non-signaling interleukin-1 receptor complex.
Protein Expression for IL1R2 Gene
Post-translational modifications for IL1R2 Gene
- A soluble form (sIL1R2) can also be produced by proteolytic cleavage at the cell surface (shedding) involving a metalloproteinase; hovever, several sIL1R2 forms ranging from 45 and 60 kDa are reported.
- Glycosylation at posLast=6666, posLast=7272, posLast=112112, posLast=219219, and isoforms=2277
- Modification sites at PhosphoSitePlus
Other Protein References for IL1R2 Gene
Antibody Products
- R&D Systems Antibodies for IL1R2 (IL-1 RII)
- Novus Biologicals Antibodies for IL1R2
- Invitrogen Antibodies for IL1R2
- antibodies-online Antibodies for IL1R2: See all 131
- GeneTex IL1R2 antibody for IL1R2
-
Santa Cruz Biotechnology (SCBT) Antibodies for IL1R2
Protein Products
- R&D Systems Proteins and Enzymes for IL1R2 (IL-1 RII)
- Search Origene for MassSpec and Protein Over-expression Lysates for IL1R2
- Origene Custom Protein Services for IL1R2
- Sino Biological Cell Lysates for IL1R2
- Sino Biological Recombinant Proteins for IL1R2
- antibodies-online Proteins for IL1R2: See all 26
- Search antibodies-online for peptides
- Search GeneTex for Proteins for IL1R2
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for IL1R2
- R&D Systems Proteome Profiler Antibody Arrays, Luminex Assays, ELISAs, and other biochemical assays for IL1R2 (IL-1 RII)
- antibodies-online Kits for IL1R2: See all 26
No data available for DME Specific Peptides for IL1R2 Gene
Domains & Families for IL1R2 Gene
Gene Families for IL1R2 Gene
Protein Domains for IL1R2 Gene
Suggested Antigen Peptide Sequences for IL1R2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P27930- Family:
-
- Belongs to the interleukin-1 receptor family.
Function for IL1R2 Gene
Molecular function for IL1R2 Gene
- GENATLAS Biochemistry:
- interleukin 1 receptor,type 2,expressed in B and T cell,with a transmembrane and an alternatively spliced soluble form
- UniProtKB/Swiss-Prot Function:
- Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004908 | interleukin-1 receptor activity | TAS | 10191101 |
| GO:0004910 | interleukin-1, Type II, blocking receptor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 1830582 |
| GO:0019966 | interleukin-1 binding | IEA | -- |
Phenotypes for IL1R2 Gene
- MGI mutant phenotypes for IL1R2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IL1R2:
Animal Models for IL1R2 Gene
- MGI Knock Outs for IL1R2:
-
- Il1r2 tm1.1(KOMP)Vlcg
Animal Model Products
-
Taconic Biosciences Mouse Models for IL1R2
- Cyagen custom Knockout/knockin (KOKI) mouse models for IL1R2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IL1R2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IL1R2 gene
- Search ViGene Biosciences for IL1R2
CRISPR Products
-
OriGene CRISPR knockouts for IL1R2
-
Santa Cruz Biotechnology (SCBT) CRISPR for IL1R2
- GenScript: Design CRISPR guide RNA sequences for IL1R2
miRNA for IL1R2 Gene
- miRTarBase miRNAs that target IL1R2
miRNA Products
- Search ViGene Biosciences for IL1R2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for IL1R2
- Browse OriGene Inhibitory RNA Products For IL1R2
-
ViGene Biosciences ready-to-package AAV shRNAs for IL1R2 gene
Clone Products
- Sino Biological Human cDNA Clone for IL1R2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IL1R2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IL1R2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for IL1R2 (IL-1 RII)
Cell Line Products
-
Horizon Cell Lines for IL1R2
-
ViGene Biosciences adenoviral particle packaged cDNA for IL1R2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IL1R2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IL1R2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IL1R2 Gene
Localization for IL1R2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IL1R2 Gene
- Isoform Short: Secreted.
- Isoform Long: Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| cytosol | 3 |
| nucleus | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for IL1R2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | MAPK signaling pathway | ||
| 2 | MAPK Pathway |
.36
|
|
| 3 | IL-2 Pathway |
.43
|
.36
|
| 4 | NF-KappaB Family Pathway | ||
| 5 | Cytokine Signaling in Immune system | ||
Pathways by source for IL1R2 Gene
3 BioSystems pathways for IL1R2 Gene
5 Reactome pathways for IL1R2 Gene
7 KEGG pathways for IL1R2 Gene
1 R&D Systems pathway for IL1R2 Gene
3 Tocris pathways for IL1R2 Gene
6 Qiagen pathways for IL1R2 Gene
Interacting Proteins for IL1R2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006955 | immune response | TAS | 8898719 |
| GO:0010955 | negative regulation of protein processing | IEA | -- |
| GO:0019221 | cytokine-mediated signaling pathway | IEA | -- |
| GO:0050712 | negative regulation of interleukin-1 alpha secretion | IEA | -- |
| GO:1900016 | negative regulation of cytokine production involved in inflammatory response | IEA | -- |
Drugs & Compounds for IL1R2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Anakinra | Approved | Pharma | antagonist | IL-1 receptor antagonist | 0 | |
| AF 12198 | Pharma | Type I IL-1 receptor antagonist, Potent, selective human type I IL-1 receptor antagonist | 0 | |||
| YM 90709 | Pharma | Interleukin-5 receptor antagonist | 0 | |||
| Ro 26-4550 trifluoroacetate | Pharma | reversible inhibitor of interleukin-2 (IL-2) binding to its receptor | 0 | |||
| IL-1 | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 6877002 |
|
433249-94-6 |
|
|
||
| Lyn peptide inhibitor |
|
222018-18-0 |
|
|
||
| R 7050 |
|
303997-35-5 |
|
|
(5) Tocris Compounds for IL1R2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 6877002 | CD40-TRAF6 interaction inhibitor | 433249-94-6 |
| AF 12198 | Potent, selective human type I IL-1 receptor antagonist | 185413-30-3 |
| Lyn peptide inhibitor | Inhibits Lyn-dependent activities of IL-5 receptor; cell-permeable | 222018-18-0 |
| R 7050 | Inhibitor of TNF-alpha receptor 1 signaling | 303997-35-5 |
| YM 90709 | Interleukin-5 receptor antagonist | 163769-88-8 |
(3) ApexBio Compounds for IL1R2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| AF 12198 | Type I IL-1 receptor antagonist | 185413-30-3 |
| Ro 26-4550 trifluoroacetate | reversible inhibitor of interleukin-2 (IL-2) binding to its receptor | 1217448-66-2 |
| YM 90709 | 163769-88-8 |
Drug Products
- ApexBio compounds for IL1R2
Transcripts for IL1R2 Gene
mRNA/cDNA for IL1R2 Gene
- (12) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (74) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for IL1R2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for IL1R2
-
Santa Cruz Biotechnology (SCBT) CRISPR for IL1R2
- GenScript: Design CRISPR guide RNA sequences for IL1R2
miRNA Products
- Search ViGene Biosciences for IL1R2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for IL1R2
- Browse OriGene Inhibitory RNA Products For IL1R2
-
ViGene Biosciences ready-to-package AAV shRNAs for IL1R2 gene
Clone Products
- Sino Biological Human cDNA Clone for IL1R2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IL1R2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IL1R2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for IL1R2 (IL-1 RII)
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - |
Expression for IL1R2 Gene
mRNA differential expression in normal tissues according to GTEx for IL1R2 Gene
This gene is overexpressed in Whole Blood (x45.0).
This gene is overexpressed in Serum (62.4) and Breast (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IL1R2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of IL1R2 Gene:
IL1R2SOURCE GeneReport for Unigene cluster for IL1R2 Gene:
Hs.25333Evidence on tissue expression from TISSUES for IL1R2 Gene
- Blood(2.6)
- Spleen(2.3)
- Lung(2.1)
Primer Products
-
OriGene qPCR primer pairs for IL1R2
-
OriGene qPCR primer pairs and template standards for IL1R2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IL1R2 Gene
Orthologs for IL1R2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IL1R2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | IL1R2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | IL1R2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Il1r2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Il1r2 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | IL1R2 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | IL1R2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | IL1R2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | IL1R2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | il1r2 34 |
|
- Species where no ortholog for IL1R2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for IL1R2 Gene
Variants for IL1R2 Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000091265 | -- | 101,998,067(+) | AGGAG(A/G)AAAAC | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1000419466 | -- | 101,990,782(+) | TTGAC(A/C)ATCTC | upstream-variant-2KB | |
| rs1000430549 | -- | 102,014,885(+) | CTCTT(-/C)CCTTT | intron-variant | |
| rs1000676586 | -- | 102,002,214(+) | GTATT(C/G)AGAGG | intron-variant, upstream-variant-2KB | |
| rs1000692143 | -- | 101,996,333(+) | CAGGG(A/C)AAGCC | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv6980n54 | CNV | loss | 21841781 |
| esv2657953 | CNV | deletion | 23128226 |
| esv2720456 | CNV | deletion | 23290073 |
| esv2720457 | CNV | deletion | 23290073 |
| esv2720458 | CNV | deletion | 23290073 |
| esv2720459 | CNV | deletion | 23290073 |
| esv3353381 | CNV | duplication | 20981092 |
| esv3426758 | CNV | duplication | 20981092 |
| nsv1132501 | CNV | duplication | 24896259 |
| nsv1146528 | CNV | insertion | 26484159 |
| nsv582551 | CNV | loss | 21841781 |
| nsv582552 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
59.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.86;
34.81% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for IL1R2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IL1R2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL1R2 Gene
Disorders for IL1R2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| endometriosis |
|
|
| joint disorders |
|
|
Search IL1R2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for IL1R2
No data available for UniProtKB/Swiss-Prot and Genatlas for IL1R2 Gene
Publications for IL1R2 Gene
- Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q. (PMID: 10191101) Dale M. … Nicklin M.J. (Genomics 1999) 2 3 22 64
- A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. (PMID: 1833184) McMahan C.J. … Sims J.E. (EMBO J. 1991) 2 3 4 64
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. (PMID: 21297633) Anderson C.A. … Rioux J.D. (Nat. Genet. 2011) 3 46 64
- Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PMID: 20452482) Romero R. … Menon R. (Am. J. Obstet. Gynecol. 2010) 3 46 64
- Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PMID: 20503287) Schuurhof A. … Janssen R. (Pediatr. Pulmonol. 2010) 3 46 64
Products for IL1R2 Gene
- R&D Systems Antibodies for IL1R2 (IL-1 RII)
- R&D Systems Proteins and Enzymes for IL1R2 (IL-1 RII)
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for IL1R2 (IL-1 RII)
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- Custom Antibody ServicesOriGene Antibodies for IL1R2
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for IL1R2
- Browse OriGene Inhibitory RNA Products For IL1R2
- OriGene qPCR primer pairs and template standards for IL1R2
- OriGene qPCR primer pairs for IL1R2
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- GenScript: Design CRISPR guide RNA sequences for IL1R2
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- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Human cDNA Clone for IL1R2
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
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- Sino Biological CRO Services for Proteins, Antibodies and Genes
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- Novus Biologicals Antibodies for IL1R2
- Novus Biologicals proteins and lysates for IL1R2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for IL1R2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for IL1R2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for IL1R2
- antibodies-online Antibodies for IL1R2: See all 131
- antibodies-online Kits for IL1R2: See all 26
- antibodies-online Proteins for IL1R2: See all 26
- Search antibodies-online for peptides
- GeneTex IL1R2 antibody for IL1R2
- Search GeneTex for Proteins for IL1R2
- ViGene Biosciences adenoviral particle packaged cDNA for IL1R2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IL1R2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IL1R2 gene
- Search ViGene Biosciences for IL1R2
- Santa Cruz Biotechnology (SCBT) Antibodies for IL1R2
- Search Santa Cruz Biotechnology (SCBT) for IL1R2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IL1R2
- Horizon Cell Lines for IL1R2
- Cyagen custom Knockout/knockin (KOKI) mouse models for IL1R2
- VectorBuilder custom plasmid, inducible vectors for IL1R2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IL1R2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for IL1R2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer