IL18BP Gene
protein-coding GIFtS: 51
GCID: GC11P071709
|
|
interleukin 18 binding protein
| |
Aliases
for IL18BP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Interleukin 18 Binding Protein1 2 | | MC51L-53L-54L Homolog Gene Product2 | | IL18BPa1 2 | | Tadekinig-Alfa1 | | IL-18BP2 3 | | Tadekinig-Alfa1 | | Interleukin-18-Binding Protein2 | | |
Export aliases for IL18BP gene to outside databasesPrevious GC identifers: GC11P074042 GC11P073248 GC11P071931 GC11P071435 GC11P071436 GC11P071387 GC11P068003 |
Summaries
for IL18BP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IL18BP:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18,prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting inreduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternativelyspliced transcript variants encoding different isoforms have been described for this gene. (provided by RefSeq, Feb2011)
UniProtKB/Swiss-Prot: I18BP_HUMAN, O95998Function: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokineresponse
Gene Wiki entry for IL18BP
|
Genomic Views
for IL18BP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IL18BP gene promoter:
STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for IL18BP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL18BP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.4 HGNC cytogenetic band: 11q13IL18BP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P071709: view genomic region
(about GC identifiers)
Start:
|
71,709,587 bp from pter |
End:
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71,716,761 bp from pter |
Size:
|
7,175 bases |
Orientation:
|
plus strand |
|
Proteins
for IL18BP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: I18BP_HUMAN, O95998 (See
protein sequence)Recommended Name: Interleukin-18-binding protein precursor Size: 194 amino acids; 21099 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAD17187.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAD17188.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAD17189.1;Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=AAD17190.1; Type=Erroneous initiation;Note=Translation N-terminally extended; Sequence=AAD17191.1; Type=Erroneous initiation; Note=Translation N-terminallyextended; Sequence=AAD17192.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=AAF31697.1;Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B3KUZ0 B7WPK4 O95993 O96027 Q9NZA9 Q9UBR7Alternative splicing: 3 isoforms: O95998-2 O95998-3 O95998-4 Explore the universe of human proteins at neXtProt for IL18BP: NX_O95998
Post-translational modifications:
N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53:HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4(major) and Hex6HexNAc5 (minor); N-glycan at Asn-147: dHex1Hex5HexNAc41
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95998
IL18BP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001034748.1 NP_001034749.1 NP_001138527.1 NP_001138529.1 NP_005690.2 NP_766630.2 NP_766632.2
ENSEMBL proteins: ENSP00000377306 ENSP00000434717 ENSP00000377308 ENSP00000338723 ENSP00000434835 ENSP00000343309 ENSP00000434376 ENSP00000377310 ENSP00000384212 ENSP00000260049
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
IL18BP for ontologies About GeneDecksing
IL18BP Antibody Products:
Assay Products for IL18BP: |
Protein
Domains /
Families
for IL18BP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IL18BP for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O95998ProtoNet protein and cluster: O95998 UniProtKB/Swiss-Prot: I18BP_HUMAN, O95998Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain |
Function
for IL18BP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: I18BP_HUMAN, O95998Function: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokineresponse Genatlas biochemistry entry for IL18BP:interleukin 18 binding protein homolog to several poxvirus proteins,expressed in the spleen inhibitor of the early Th1cytokine response,abolishing IL18 induction of INF gamma
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for IL18BP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL18BP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL18BP |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
IL18BP for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Il18bptm1Lex for IL18BP
1 MGI phenotypic allele  for Il18bp (no phenotypes)
IL18BP for phenotypes About GeneDecksing
|
Pathways & Interactions
for IL18BP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL18BP
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for IL18BP (O959983 ENSP000002600494) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0032496 | response to lipopolysaccharide |
IEA | -- | | GO:0042088 | T-helper 1 type immune response |
IDA | 10023777 | | GO:0070301 | cellular response to hydrogen peroxide |
IEA | -- | | GO:0071356 | cellular response to tumor necrosis factor |
IEA | -- | | GO:1900116 | extracellular negative regulation of signal transduction |
TAS | 11890646 |
IL18BP for ontologies About GeneDecksing
|
Drugs & Compounds
for IL18BP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
IL18BP for compounds About GeneDecksing
 Browse Tocris compounds for IL18BP
3 Novoseek chemical compound relationships for IL18BP gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| endotoxin |
12.3 |
1 |
10094485 (1) |
| alanine |
9.13 |
1 |
16979683 (1) |
| creatinine |
0 |
3 |
14640238 (1), 11890646 (1), 11226333 (1) |
Search CenterWatch for drugs/clinical trials and news about IL18BP / I18BP
|
Transcripts
for IL18BP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IL18BP gene (8 alternative transcripts): NM_001039659.1 NM_001039660.1 NM_001145055.1 NM_001145057.1 NM_005699.3 NM_173042.2 NM_173044.2 NM_173043.1 Unigene Cluster for IL18BP: Interleukin 18 binding protein Hs.591967 [show with all ESTs]Unigene Representative Sequence: AF11080113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393703 ENST00000497194(uc001ore.1 uc001orf.1 uc021qmv.1 uc001org.1 uc001ori.2 uc001orh.2)
ENST00000393705 ENST00000525932 ENST00000414358 ENST00000531777 ENST00000337131
ENST00000531053 ENST00000343898(uc009ysv.1) ENST00000534583 ENST00000393707
ENST00000404792 ENST00000260049
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 7): IL18BP (NM_001039660) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL18BP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL18BP |
Additional cDNA sequence: AB019504.1 AF086560.1 AF110799.1 AF110800.1 AF110801.1 AF122906.1 BC044215.1 14 DOTS entries: DT.402907 DT.100881038 DT.95336437 DT.91884303 DT.100881043 DT.40132911 DT.95201570 DT.448720 DT.100881042 DT.92387733 DT.120712045 DT.91659804 DT.95201565 DT.100045744 24/108 AceView cDNA sequences (see all 108): NM_173044 BF724662 CR606710 AF110800 BQ920140 NM_005699 NM_173042 AF110799 CR605363 AF122906 AB019504 NM_173043 BX357194 BI822872 BQ918945 BU541912 BM312497 BU752588 BU430639 CB154498 BM819966 AI521549 AF215907 AA777410
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for IL18BP (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for IL18BP
|
Expression
for IL18BP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IL18BP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See IL18BP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IL18BP
SOURCE GeneReport for Unigene cluster: Hs.591967
UniProtKB/Swiss-Prot: I18BP_HUMAN, O95998Tissue specificity: Strongly expressed in heart, lung, placenta and spleen
SABiosciences Custom PCR Arrays for IL18BP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL18BP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IL18BP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL18BP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL18BP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL18BP |
Orthologs
for IL18BP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for IL18BP gene from 1/5 species (see all 5) About this table
ENSEMBL Gene Tree for IL18BP (if available)
TreeFam Gene Tree for IL18BP (if available) |
Paralogs
for IL18BP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for IL18BP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IL18BP (71709587 - 71716761 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IL18BP: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL18BP |
|
Disorders
/ Diseases
for IL18BP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IL18BP for disorders About GeneDecksing
OMIM gene information: 604113
OMIM disorders: --
20/43  diseases for IL18BP (see all 43): About MalaCardscrohn's disease molluscum contagiosum adult-onset still's disease graft versus host disease
traumatic brain injury wegener's granulomatosis brain injury cowpox
smallpox systemic lupus erythematosus lupus erythematosus inflammatory bowel disease
head injury rheumatoid arthritis lupus nephritis intrahepatic cholangiocarcinoma
skin disease myocardial infarction nephritis liver disease
10/15 Novoseek disease relationships for IL18BP gene (see all 15) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ectromelia |
79.3 |
6 |
10769064 (2), 15105546 (1), 15193916 (1), 19104048 (1) |
| molluscum contagiosum |
68.8 |
3 |
15105546 (1), 16091916 (1) |
| smallpox |
53.8 |
5 |
15193916 (1), 16979683 (1), 17959666 (1), 19104048 (1) |
| cowpox |
50.2 |
2 |
10769064 (2) |
| rheumatoid arthritis |
34.3 |
9 |
15188356 (2), 12626794 (1), 19225717 (1), 12632414 (1) (see all 6) |
| inflammation |
32.4 |
4 |
12172382 (1), 12874202 (1), 12462332 (1), 19805173 (1) |
| colon carcinoma |
25.9 |
4 |
19046253 (2), 10673399 (1) |
| autoimmune diseases |
24 |
1 |
19104048 (1) |
| necrosis |
7.61 |
2 |
11447182 (1) |
| liver diseases |
2.14 |
5 |
20422882 (3), 12462332 (1) |
Genetic Association Database (GAD): IL18BP
Human Genome Epidemiology (HuGE) Navigator: IL18BP (8 documents)
Export disorders for IL18BP gene to outside databases
|
Publications
for IL18BP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IL18BP gene, integrated from 9 sources (see all 121):
(articles sorted by number of sources associating them with IL18BP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. (PubMed id 10023777)1, 2, 3, 9 Novick D....Rubinstein M. (1999)
- Cloning and expression of interleukin-18 binding protein. (PubMed id 10094485)1, 2, 9 Aizawa Y.... Kurimoto M. (1999)
- Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. (PubMed id 10655506)1, 2, 9 Kim S.-H.... Dinarello C.A. (2000)
- Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease. (PubMed id 16043644)1, 4 Tiret L....Blankenberg S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus. (PubMed id 10329540)1, 2 Xiang Y. and Moss B. (1999)
- Regulation of interleukin-18 binding protein production by blood and synovial cells from patients with rheumatoid arthritis. (PubMed id 15188356)1, 9 Kawashima M....Miossec P. (2004)
- Novel targets for interleukin 18 binding protein. (PubMed id 11890646)1, 9 Dinarello C.A. (2001)
|
External Searches for IL18BP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IL18BP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IL18BP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IL18BP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IL18BP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IL18BP gene:
Search GeneIP for patents involving IL18BP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IL18BP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for IL18BP | | OriGene shRNA RFP for IL18BP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IL18BP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL18BP | | | OriGene Protein Over-expression Lysate for IL18BP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IL18BP | | OriGene 3'-UTR Clone for IL18BP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL18BP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IL18BP | | OriGene Custom Protein Services for IL18BP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IL18BP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL18BP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL18BP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL18BP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL18BP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL18BP |
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| | | | Search Tocris compounds for IL18BP |
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 | | | IL18BP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL18BP |
|  |  |  | | | | ThermoFisher Antibodies for IL18BP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL18BP |
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