Aliases for IL18 Gene
External Ids for IL18 Gene
Previous GeneCards Identifiers for IL18 Gene
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
GeneCards Summary for IL18 Gene
IL18 (Interleukin 18) is a Protein Coding gene. Diseases associated with IL18 include Adult-Onset Still's Disease and Sapho Syndrome. Among its related pathways are PEDF Induced Signaling and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. GO annotations related to this gene include cytokine activity.
UniProtKB/Swiss-Prot for IL18 Gene
Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.