Aliases for IL18 Gene
External Ids for IL18 Gene
Previous GeneCards Identifiers for IL18 Gene
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
GeneCards Summary for IL18 Gene
IL18 (Interleukin 18) is a Protein Coding gene. Diseases associated with IL18 include Adult-Onset Still's Disease and Pleural Tuberculosis. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include cytokine activity.
UniProtKB/Swiss-Prot for IL18 Gene
Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.