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Aliases for IL17REL Gene

Aliases for IL17REL Gene

  • Interleukin 17 Receptor E-Like 2 3
  • IL-17 Receptor E-Like 3 4
  • IL-17RE-Like 3 4
  • Putative Interleukin-17 Receptor E-Like 3

External Ids for IL17REL Gene

Previous GeneCards Identifiers for IL17REL Gene

  • GC22M048775
  • GC22M050432
  • GC22M033332

Summaries for IL17REL Gene

GeneCards Summary for IL17REL Gene

IL17REL (Interleukin 17 Receptor E-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IL17REL Gene

Genomics for IL17REL Gene

Regulatory Elements for IL17REL Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IL17REL Gene

Start:
49,994,513 bp from pter
End:
50,012,659 bp from pter
Size:
18,147 bases
Orientation:
Minus strand

Genomic View for IL17REL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IL17REL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IL17REL Gene

Proteins for IL17REL Gene

  • Protein details for IL17REL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZVW7-I17EL_HUMAN
    Recommended name:
    Putative interleukin-17 receptor E-like
    Protein Accession:
    Q6ZVW7
    Secondary Accessions:
    • A6NCN4
    • A6PVC1

    Protein attributes for IL17REL Gene

    Size:
    336 amino acids
    Molecular mass:
    37514 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IL17REL Gene

Proteomics data for IL17REL Gene at MOPED

Post-translational modifications for IL17REL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IL17REL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IL17REL Gene

Domains for IL17REL Gene

Protein Domains for IL17REL Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IL17REL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IL17REL: view

No data available for Gene Families and UniProtKB/Swiss-Prot for IL17REL Gene

Function for IL17REL Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IL17REL Gene

Localization for IL17REL Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IL17REL Gene COMPARTMENTS Subcellular localization image for IL17REL gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IL17REL Gene

Pathways for IL17REL Gene

SuperPathways for IL17REL Gene

No Data Available

Interacting Proteins for IL17REL Gene

Gene Ontology (GO) - Biological Process for IL17REL Gene

None

No data available for Pathways by source for IL17REL Gene

Transcripts for IL17REL Gene

mRNA/cDNA for IL17REL Gene

(2) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IL17REL Gene

Interleukin 17 receptor E-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IL17REL

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for IL17REL
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IL17REL Gene

No ASD Table

Relevant External Links for IL17REL Gene

GeneLoc Exon Structure for
IL17REL
ECgene alternative splicing isoforms for
IL17REL

Expression for IL17REL Gene

mRNA expression in normal human tissues for IL17REL Gene

mRNA differential expression in normal tissues according to GTEx for IL17REL Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (10.1), Stomach (8.0), and Brain - Cortex (5.2).

SOURCE GeneReport for Unigene cluster for IL17REL Gene Hs.526712

genes like me logo Genes that share expressions with IL17REL: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for IL17REL Gene

Orthologs for IL17REL Gene

This gene was present in the common ancestor of chordates.

Orthologs for IL17REL Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IL17REL 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia IL17REL 35
  • 77.46 (n)
  • 69.52 (a)
IL17REL 36
  • 69 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IL17REL 35
  • 79.24 (n)
  • 71.17 (a)
IL17REL 36
  • 65 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IL17REL 36
  • 41 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IL17REL 36
  • 37 (a)
OneToOne
chicken
(Gallus gallus)
Aves IL17REL 35
  • 52.71 (n)
  • 48.44 (a)
IL17REL 36
  • 38 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia il17rel 35
  • 50.24 (n)
  • 41.37 (a)
zebrafish
(Danio rerio)
Actinopterygii il17rel 36
  • 26 (a)
OneToOne
LOC100331195 35
  • 45.96 (n)
  • 39.65 (a)
Species with no ortholog for IL17REL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IL17REL Gene

ENSEMBL:
Gene Tree for IL17REL (if available)
TreeFam:
Gene Tree for IL17REL (if available)

Paralogs for IL17REL Gene

No data available for Paralogs for IL17REL Gene

Variants for IL17REL Gene

Sequence variations from dbSNP and Humsavar for IL17REL Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs137841 -- 49,994,175(+) GCCCC(A/C)CACTG downstream-variant-500B
rs137842 -- 49,994,316(+) GTGAC(A/G)CTGAC downstream-variant-500B
rs137843 -- 49,996,190(+) GGAAA(C/G)GGTCT utr-variant-3-prime
rs137844 -- 49,998,418(+) GTCCT(-/CCT)ATGGG intron-variant
rs137845 -- 50,001,001(+) GCCCA(A/G)GGTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IL17REL Gene

Variant ID Type Subtype PubMed ID
dgv5046n71 CNV Loss 21882294
nsv915495 CNV Loss 21882294
dgv5049n71 CNV Loss 21882294
dgv5050n71 CNV Loss 21882294
nsv915508 CNV Loss 21882294
nsv915512 CNV Gain 21882294
dgv5051n71 CNV Loss 21882294
nsv829329 CNV Gain 20364138
dgv5052n71 CNV Loss 21882294
dgv5053n71 CNV Loss 21882294
nsv915519 CNV Loss 21882294
nsv915520 CNV Loss 21882294
esv2724729 CNV Deletion 23290073
esv2673064 CNV Deletion 23128226
esv2607894 CNV Insertion 19546169

Relevant External Links for IL17REL Gene

HapMap Linkage Disequilibrium report
IL17REL
Human Gene Mutation Database (HGMD)
IL17REL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL17REL Gene

Disorders for IL17REL Gene

Relevant External Links for IL17REL

Genetic Association Database (GAD)
IL17REL
Human Genome Epidemiology (HuGE) Navigator
IL17REL
genes like me logo Genes that share disorders with IL17REL: view

No data available for UniProtKB/Swiss-Prot for IL17REL Gene

Publications for IL17REL Gene

  1. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). (PMID: 20228798) Franke A. … Schreiber S. (Nat. Genet. 2010) 3 48
  2. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. (PMID: 21297633) Anderson C.A. … Rioux J.D. (Nat. Genet. 2011) 3 48
  3. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3
  4. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for IL17REL Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate IL17REL
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for IL17REL
  • Block miRNA regulation of IL17REL using miScript Target Protectors

Sources for IL17REL Gene

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