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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IL17RB Gene

protein-coding   GIFtS: 59
GCID: GC03P053855

Interleukin 17 Receptor B

(Previous name: interleukin 17B receptor)
(Previous symbol: IL17BR)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Interleukin 17 Receptor B1 2     IL-17 Receptor B2 3
IL17BR1 2 3 5     IL-17 Receptor Homolog 12 3
Interleukin 17B Receptor1 2     IL-17B Receptor2 3
Cytokine Receptor-Like 42 3     IL17RH12 5
Interleukin-17B Receptor2 3     Cytokine Receptor CRL42
CRL42 3     Interleukin 17 Receptor Homolog 12
EVI272 3     Interleukin-17 Receptor B2
IL-17RB2 3     IL17Rh13
IL-17Rh12 3     

External Ids:    HGNC: 180151   Entrez Gene: 555402   Ensembl: ENSG000000567367   OMIM: 6054585   UniProtKB: Q9NRM63   

Export aliases for IL17RB gene to outside databases

Previous GC identifers: GC03P053735 GC03P053837


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IL17RB Gene:
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but
does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the
production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be
significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this
receptor. (provided by RefSeq, Jul 2008)

GeneCards Summary for IL17RB Gene: 
IL17RB (interleukin 17 receptor B) is a protein-coding gene. Diseases associated with IL17RB include esophageal adenocarcinoma, and rabies, and among its related super-pathways are Mucin expression in CF via IL-6, IL-17 signaling pathways and STAT3 Pathway. GO annotations related to this gene include cytokine receptor activity. An important paralog of this gene is IL17RA.

UniProtKB/Swiss-Prot: I17RB_HUMAN, Q9NRM6
Function: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth
and/or differentiation of hematopoietic cells

Gene Wiki entry for IL17RB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IL17RB gene promoter:
         S8   POU2F1   Tal-1beta   ITF-2   NF-kappaB   NF-kappaB1   YY1   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIL17RB promoter sequence
   Search SABiosciences Chromatin IP Primers for IL17RB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL17RB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.1   Ensembl cytogenetic band:  3p21.1   HGNC cytogenetic band: 3p21.1

IL17RB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IL17RB gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P053855:  view genomic region     (about GC identifiers)

Start:
53,880,577 bp from pter      End:
53,899,827 bp from pter
Size:
19,251 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: I17RB_HUMAN, Q9NRM6 (See protein sequence)
Recommended Name: Interleukin-17 receptor B precursor  
Size: 502 amino acids; 55885 Da
Subunit: Interacts with DAZAP2
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform 2: Secreted
Secondary accessions: Q9BPZ0 Q9NRL4 Q9NRM5
Alternative splicing: 2 isoforms:  Q9NRM6-1   Q9NRM6-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for IL17RB: NX_Q9NRM6

Explore proteomics data for IL17RB at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRM6

  • IL17RB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IL17RB Protein Expression
    REFSEQ proteins: NP_061195.2  
    ENSEMBL proteins: 
     ENSP00000288167   ENSP00000418638  

    Human Recombinant Protein Products for IL17RB: 
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    Sino Biological Cell Lysate for IL17RB 
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    Cloud-Clone Corp. Proteins for IL17RB 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005737cytoplasm IEA--
    GO:0005887integral to plasma membrane TAS10749887
    GO:0009986cell surface IEA--
    GO:0016020membrane NAS10815801

    IL17RB for ontologies           About GeneDecksing



    IL17RB Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IL: Interleukins and interleukin receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: Interleukin 17 receptor B 
    IL-17 receptor family

    1 InterPro protein domain:
     IPR013568 SEFIR

    Graphical View of Domain Structure for InterPro Entry Q9NRM6

    ProtoNet protein and cluster: Q9NRM6

    1 Blocks protein domain: IPB013568 SEFIR

    UniProtKB/Swiss-Prot: I17RB_HUMAN, Q9NRM6
    Similarity: Contains 1 SEFIR domain


    IL17RB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: I17RB_HUMAN, Q9NRM6
    Function: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth
    and/or differentiation of hematopoietic cells

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004896cytokine receptor activity NAS10815801
         
    IL17RB for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Il17rb):
     cellular  hematopoietic system  immune system  respiratory system  skeleton 

    IL17RB for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for IL17RB: Il17rbtm1Anjm Il17rbtm1Bud Il17rbtm1Hwata

       inGenious Targeting Laboratory - Custom generated mouse model solutions for IL17RB 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate IL17RB:
    hsa-miR-664
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for IL17RB About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Mucin expression in CF via IL-6, IL-17 signaling pathways
    IL-17 Signaling0.48
    2PEDF Induced Signaling
    Cytokine-cytokine receptor interaction0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for IL17RB
        IL-17 Signaling




    1         Kegg Pathway  (Kegg details for IL17RB):
        Cytokine-cytokine receptor interaction


    IL17RB for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IL17RB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/9 Interacting proteins for IL17RB (Q9NRM63 ENSP000002881674) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IL25Q9H2933, ENSP000003281114I2D: score=3 STRING: ENSP00000328111
    PCNAP120043, ENSP000003684384I2D: score=1 STRING: ENSP00000368438
    IL17BQ9UHF53, ENSP000002617964I2D: score=3 STRING: ENSP00000261796
    SETD8Q9NQR13, ENSP000003329954I2D: score=1 STRING: ENSP00000332995
    IL17RDQ8NFM73I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001558regulation of cell growth NAS10815801
    GO:0006952defense response TAS10749887
    GO:0019221cytokine-mediated signaling pathway NAS10815801

    IL17RB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IL17RB (I17RB)

    Search CenterWatch for drugs/clinical trials and news about IL17RB / I17RB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IL17RB gene (2 alternative transcripts): 
    NM_018725.3  NM_172234.1  

    Unigene Cluster for IL17RB:

    Interleukin 17 receptor B
    Hs.654970  [show with all ESTs]
    Unigene Representative Sequence: NM_018725
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000288167(uc003dha.3) ENST00000475124 ENST00000494338
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate IL17RB:
    hsa-miR-664
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    Inhib. RNA
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    Additional mRNA sequence: 

    AF208110.1 AF212365.1 AF250309.1 AK307749.1 AY359122.1 BC000980.1 

    7 DOTS entries:

    DT.451577  DT.91765740  DT.100787928  DT.95167453  DT.95167455  DT.95167457  DT.307855 

    24/85 AceView cDNA sequences (see all 85):

    NM_018725 AA007528 BX483104 CR615594 AI913613 BM693867 AW673932 BC000980 
    AY359122 BQ226353 AV660618 AV728939 NM_172234 BX453537 AF212365 BE539514 
    AV728945 AF208110 BF740045 W61239 AF208111 AI744263 BI823321 AW236941 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for IL17RB    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c
    SP1:                                      -     -     -                                       
    SP2:                                                                                          
    SP3:                                                        -                                 
    SP4:                                                  -                                       


    ECgene alternative splicing isoforms for IL17RB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IL17RB expression in normal human tissues (normalized intensities)      IL17RB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAGCAAGA
    IL17RB Expression
    About this image


    IL17RB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/15 selected tissues (see all 15) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Kidney (Urinary System)
             kidney ; cells in tubules   
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Thymus (Hematopoietic System)
             Thymus
     
     Uterus (Reproductive System)
             cervix   

    See IL17RB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IL17RB

    SOURCE GeneReport for Unigene cluster: Hs.654970

    UniProtKB/Swiss-Prot: I17RB_HUMAN, Q9NRM6
    Tissue specificity: Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas,
    testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most
    cell lines

        SABiosciences Expression via Pathway-Focused PCR Arrays including IL17RB: 
              Th17 Response in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat
              Allergy & Asthma in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL17RB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IL17RB gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Il17rb1 , 5 interleukin 17 receptor B1, 5 79.38(n)1
    75.3(a)1
      14 (18.39 cM)5
    509051  NM_019583.31  NP_062529.21 
     299961415 
    lizard
    (Anolis carolinensis)
    Reptilia IL17RB6
    interleukin 17 receptor B
    40(a)
    1 ↔ 1
    2(160547160-160567783)


    ENSEMBL Gene Tree for IL17RB (if available)
    TreeFam Gene Tree for IL17RB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IL17RB gene
    IL17RA2  

    IL17RB for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/502 SNPs in IL17RB are shown (see all 502)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1887734001,2
    --53882438(+) CACCTA/GTGGTC 1 -- int10--------
    rs1920837181,2
    --53882504(+) GGTCCA/GTCATA 1 -- int10--------
    rs22323331,2
    C,F--53882661(+) CTTCAA/GCATGA 1 -- int115Minor allele frequency- G:0.22NS NA WA EU 2294
    rs10256901,2
    C,F,O,A,H--53882663(-) CGTCAT/CGTTGA 1 -- int127Minor allele frequency- C:0.22NA EA NS WA CSA EU 3653
    rs58490091,2
    C--53882673(+) CTTGGT/-TTTTT 1 -- int1 trp32Minor allele frequency- -:0.00NA CSA 4
    rs2007845721,2
    C--53882673(-) AAAAAA/CCAAGC 1 -- int10--------
    rs1402549231,2
    C,F--53882694(+) AGACCG/ATTCAA 2 /I /V mis11Minor allele frequency- A:0.00NA 4550
    rs1124859711,2
    C--53882699(+) GTTCAG/ATGTGG 2 /Q syn11Minor allele frequency- A:0.50CSA 2
    rs76506861,2
    C--53882795(+) GGCAAT/CAGGTC 1 -- int14Minor allele frequency- C:0.02NS WA 246
    rs22768391,2
    C,F,H--53882903(+) AGGCCG/CTGTTT 1 -- int125Minor allele frequency- C:0.12EA NS NA WA 3432

    HapMap Linkage Disequilibrium report for IL17RB (53880577 - 53899827 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for IL17RB:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv876803CNV Loss21882294
    nsv876805CNV Loss21882294
    dgv283n21CNV Loss19592680
    nsv876804CNV Gain21882294


    Human Gene Mutation Database (HGMD): IL17RB
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605458    OMIM disorders: --

    14 diseases for IL17RB:    About MalaCards
    esophageal adenocarcinoma    rabies    allergic rhinitis    rhinitis
    cytochrome p450    hepatitis b    asthma    rheumatoid arthritis
    arthritis    esophagitis    hepatitis    squamous cell carcinoma
    adenocarcinoma    breast cancer


    IL17RB for disorders           About GeneDecksing

    Genetic Association Database (GAD): IL17RB
    Human Genome Epidemiology (HuGE) Navigator: IL17RB (9 documents)

    Export disorders for IL17RB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IL17RB gene, integrated from 9 sources (see all 39):
    (articles sorted by number of sources associating them with IL17RB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evi27 encodes a novel membrane protein with homology to the IL17 receptor. (PubMed id 10815801)1, 2, 3, 9 Tian E....Shaughnessy J.D. Jr. (2000)
    2. A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity. (PubMed id 10749887)1, 2, 3 Shi Y.... Ebner R. (2000)
    3. Association of IL-17RB gene polymorphism with asthma. (PubMed id 19118269)1, 4, 9 Jung J.S....Shin H.D. (2009)
    4. Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance. (PubMed id 18794098)1, 4, 9 Goetz M.P....Ingle J.N. (2008)
    5. Smurf2 regulates IL17RB by proteasomal degradation of its novel binding partner DAZAP2. (PubMed id 22070932)1, 2 Popova A.... Gratchev A. (2012)
    6. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    7. Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1, 4 Flachsbart F....Nebel A. (2010)
    8. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    9. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    10. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55540 HGNC: 18015 AceView: IL17RB Ensembl:ENSG00000056736 euGenes: HUgn55540
    ECgene: IL17RB Kegg: 55540 H-InvDB: IL17RB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IL17RB Pharmacogenomics, SNPs, Pathways
    SeattleSNPshttp://pga.gs.washington.edu/data/il17rb/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IL17RB gene:
    Search GeneIP for patents involving IL17RB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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