Aliases for IL17F Gene
External Ids for IL17F Gene
Previous GeneCards Identifiers for IL17F Gene
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL17F Gene
IL17F (Interleukin 17F) is a Protein Coding gene. Diseases associated with IL17F include candidiasis, familial, 6, autosomal dominant and chronic mucocutaneous candidiasis. Among its related pathways are IL-17 Family Signaling Pathways and IL-17 Family Signaling Pathways. GO annotations related to this gene include protein homodimerization activity and cytokine binding. An important paralog of this gene is IL17A.
UniProtKB/Swiss-Prot for IL17F Gene
Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis