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Aliases for IL12B Gene

Aliases for IL12B Gene

  • Interleukin 12B 2 3 5
  • Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) 2 3
  • Natural Killer Cell Stimulatory Factor, 40 KD Subunit 2 3
  • Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit 3 4
  • NK Cell Stimulatory Factor Chain 2 3 4
  • Interleukin-12 Beta Chain 2 3
  • Interleukin 12, P40 2 3
  • IL12, Subunit P40 2 3
  • IL-12 Subunit P40 3 4
  • CLMF P40 3 4
  • IL-12B 3 4
  • NKSF2 3 4
  • Cytotoxic Lymphocyte Maturation Factor 2, P40 2
  • Natural Killer Cell Stimulatory Factor-2 2
  • Interleukin-12 Subunit Beta 3
  • IMD28 3
  • CLMF2 3
  • IMD29 3
  • CLMF 3
  • NKSF 3

External Ids for IL12B Gene

Previous HGNC Symbols for IL12B Gene

  • NKSF2

Previous GeneCards Identifiers for IL12B Gene

  • GC05M158596
  • GC05M159251
  • GC05M158722
  • GC05M158674
  • GC05M153836
  • GC05M158741

Summaries for IL12B Gene

Entrez Gene Summary for IL12B Gene

  • This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

GeneCards Summary for IL12B Gene

IL12B (Interleukin 12B) is a Protein Coding gene. Diseases associated with IL12B include Immunodeficiency 29, Mycobacteriosis and Familial Atypical Mycobacteriosis, Il12b-Related. Among its related pathways are Allograft rejection and Akt Signaling. GO annotations related to this gene include protein homodimerization activity and protein heterodimerization activity.

UniProtKB/Swiss-Prot for IL12B Gene

  • Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

  • Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Gene Wiki entry for IL12B Gene

Additional gene information for IL12B Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IL12B Gene

Genomics for IL12B Gene

Regulatory Elements for IL12B Gene

Enhancers for IL12B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H159411 1.4 FANTOM5 Ensembl ENCODE 31.1 -81.7 -81720 1 KLF1 MAX EBF1 RELA POLR2A EED PATZ1 ATF7 PRDM10 ETV6 IL12B LOC285626 RNF145 GC05P159421
GH05H159459 1.1 FANTOM5 Ensembl 30.5 -129.4 -129396 0 EBF1 BATF RELA EED ZNF207 FOS ETV6 RUNX3 IKZF2 CREM IL12B LOC285626 RNF145 GC05P159459 GC05P159458 LINC01845
GH05H159456 0.9 FANTOM5 30.4 -126.0 -125980 0 PKNOX1 TBL1XR1 SIN3A BMI1 BATF ZNF207 FOS ATF7 ETV6 RUNX3 IL12B LOC285626 RNF145 GC05P159458 GC05P159459 GC05P159421
GH05H159450 1.4 FANTOM5 Ensembl ENCODE 17.4 -120.6 -120644 1 GTF2F1 MXI1 JUN MAX FEZF1 RAD21 FOSL1 ZNF316 POLR2A RCOR1 IL12B RNF145 GC05P159459 GC05P159458 GC05P159421
GH05H159335 1.5 FANTOM5 Ensembl ENCODE 13.5 -6.5 -6461 3 HDAC1 PKNOX1 ATF1 ZBTB40 ZNF766 GATA2 ELK1 ATF7 ETV6 CREM IL12B PWWP2A EBF1 RNF145 GC05P159421
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IL12B on UCSC Golden Path with GeneCards custom track

Promoters for IL12B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000189836 -813 601 SIN3A ZNF2 ZNF121 ZNF143 REST GLIS1 NBN KDM1A SP7 ZNF785

Genomic Location for IL12B Gene

Chromosome:
5
Start:
159,314,783 bp from pter
End:
159,330,887 bp from pter
Size:
16,105 bases
Orientation:
Minus strand

Genomic View for IL12B Gene

Genes around IL12B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IL12B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IL12B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IL12B Gene

Proteins for IL12B Gene

  • Protein details for IL12B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P29460-IL12B_HUMAN
    Recommended name:
    Interleukin-12 subunit beta
    Protein Accession:
    P29460

    Protein attributes for IL12B Gene

    Size:
    328 amino acids
    Molecular mass:
    37169 Da
    Quaternary structure:
    • Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.

    Three dimensional structures from OCA and Proteopedia for IL12B Gene

neXtProt entry for IL12B Gene

Post-translational modifications for IL12B Gene

  • Known to be C-mannosylated in the recombinant protein; it is not yet known for sure if the wild-type protein is also modified.
  • Glycosylation at isoforms=135, posLast=222222, and isoforms=319
  • Modification sites at PhosphoSitePlus

Other Protein References for IL12B Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • R&D Systems Antibodies for IL12B (IL-12/IL-23 p40)

No data available for DME Specific Peptides for IL12B Gene

Domains & Families for IL12B Gene

Gene Families for IL12B Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted secreted proteins

Suggested Antigen Peptide Sequences for IL12B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P29460

UniProtKB/Swiss-Prot:

IL12B_HUMAN :
  • Belongs to the type I cytokine receptor family. Type 3 subfamily.
Family:
  • Belongs to the type I cytokine receptor family. Type 3 subfamily.
genes like me logo Genes that share domains with IL12B: view

Function for IL12B Gene

Molecular function for IL12B Gene

GENATLAS Biochemistry:
interleukin 12,beta polypeptide (40kDa),dimerizing with IL12A,secreted by macrophages and dendritic cells,stimulating IFNG production,chemotactic molecule for macrophages,antagonizing IL12P70
UniProtKB/Swiss-Prot Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
UniProtKB/Swiss-Prot Function:
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Phenotypes From GWAS Catalog for IL12B Gene

Gene Ontology (GO) - Molecular Function for IL12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004896 cytokine receptor activity IEA --
GO:0005125 contributes_to cytokine activity IDA,IEA 1674604
GO:0005126 cytokine receptor binding IEA --
GO:0005143 contributes_to interleukin-12 receptor binding TAS 9603733
GO:0005515 protein binding IPI 7527811
genes like me logo Genes that share ontologies with IL12B: view
genes like me logo Genes that share phenotypes with IL12B: view

Human Phenotype Ontology for IL12B Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for IL12B Gene

MGI Knock Outs for IL12B:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for IL12B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for IL12B Gene

Localization for IL12B Gene

Subcellular locations from UniProtKB/Swiss-Prot for IL12B Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IL12B gene
Compartment Confidence
extracellular 5

Gene Ontology (GO) - Cellular Components for IL12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space TAS 1673147
GO:0005737 cytoplasm IEA --
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with IL12B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for IL12B Gene

Pathways & Interactions for IL12B Gene

genes like me logo Genes that share pathways with IL12B: view

SIGNOR curated interactions for IL12B Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for IL12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001916 positive regulation of T cell mediated cytotoxicity ISS --
GO:0002230 positive regulation of defense response to virus by host IEA,ISS --
GO:0002323 natural killer cell activation involved in immune response IEA --
GO:0002827 positive regulation of T-helper 1 type immune response ISS,IEA --
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IDA 7903063
genes like me logo Genes that share ontologies with IL12B: view

Drugs & Compounds for IL12B Gene

(23) Drugs for IL12B Gene - From: DrugBank, PharmGKB, DGIdb, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ustekinumab Approved, Investigational Pharma antibody, Target, Target 90
5-Mercapto-2-Nitro-Benzoic Acid Experimental Pharma Target 0
Briakinumab Investigational Pharma Target 0
humanized SMART Anti-IL-12 Antibody Investigational Pharma Target 0
Tumor necrosis factor alpha (TNF-alpha) inhibitors Pharma 0

(16) Additional Compounds for IL12B Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with IL12B: view

Transcripts for IL12B Gene

mRNA/cDNA for IL12B Gene

(1) REFSEQ mRNAs :
(12) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IL12B Gene

Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for IL12B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for IL12B Gene

No ASD Table

Relevant External Links for IL12B Gene

GeneLoc Exon Structure for
IL12B
ECgene alternative splicing isoforms for
IL12B

Expression for IL12B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IL12B Gene

mRNA differential expression in normal tissues according to GTEx for IL12B Gene

This gene is overexpressed in Pituitary (x10.9).

NURSA nuclear receptor signaling pathways regulating expression of IL12B Gene:

IL12B

SOURCE GeneReport for Unigene cluster for IL12B Gene:

Hs.674

Evidence on tissue expression from TISSUES for IL12B Gene

  • Nervous system(4.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for IL12B Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • immune
  • integumentary
  • lymphatic
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
Organs:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • head
Thorax:
  • aorta
  • heart
  • heart valve
  • lung
Limb:
  • ankle
  • digit
  • elbow
  • finger
  • foot
  • hand
  • hip
  • knee
  • lower limb
  • shoulder
  • toe
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • bone marrow
  • peripheral nervous system
  • red blood cell
  • skin
  • sweat gland
  • white blood cell
genes like me logo Genes that share expression patterns with IL12B: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IL12B Gene

Orthologs for IL12B Gene

This gene was present in the common ancestor of chordates.

Orthologs for IL12B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IL12B 33 34
  • 99.39 (n)
cow
(Bos Taurus)
Mammalia IL12B 33 34
  • 88.24 (n)
dog
(Canis familiaris)
Mammalia IL12B 33 34
  • 87.4 (n)
rat
(Rattus norvegicus)
Mammalia Il12b 33
  • 76.71 (n)
mouse
(Mus musculus)
Mammalia Il12b 33 16 34
  • 75.47 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia IL12B 34
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IL12B 34
  • 59 (a)
OneToOne
chicken
(Gallus gallus)
Aves IL12B 33
  • 56.54 (n)
IL-12B 34
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IL12B 34
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii il12ba 33 34
  • 46.27 (n)
IL12B (3 of 3) 34
  • 23 (a)
OneToMany
il12bb 34
  • 23 (a)
OneToMany
Species where no ortholog for IL12B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IL12B Gene

ENSEMBL:
Gene Tree for IL12B (if available)
TreeFam:
Gene Tree for IL12B (if available)

Paralogs for IL12B Gene

No data available for Paralogs for IL12B Gene

Variants for IL12B Gene

Sequence variations from dbSNP and Humsavar for IL12B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs587776807 Pathogenic 159,323,098(+) TTCCT(-/T)TTTTG intron-variant, reference, frameshift-variant
rs786201006 Pathogenic 159,323,113(-) GCCAT(-/TCGCTCCT)GCTGC intron-variant, reference, frameshift-variant
rs3213099 Likely benign 159,320,528(-) TCTTT(A/C/G)ACTTC intron-variant, nc-transcript-variant
rs3213113 Likely benign 159,315,876(-) TTGCC(A/C)TGGGC utr-variant-3-prime
rs3213119 Likely benign 159,316,780(-) CCACG(G/T)TCATC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for IL12B Gene

Variant ID Type Subtype PubMed ID
esv3607337 CNV gain 21293372

Variation tolerance for IL12B Gene

Residual Variation Intolerance Score: 65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.67; 45.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IL12B Gene

Human Gene Mutation Database (HGMD)
IL12B
SNPedia medical, phenotypic, and genealogical associations of SNPs for
IL12B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL12B Gene

Disorders for IL12B Gene

MalaCards: The human disease database

(10) MalaCards diseases for IL12B Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
immunodeficiency 29, mycobacteriosis
  • mendelian susceptibility to mycobacterial diseases due to complete il12b deficiency
familial atypical mycobacteriosis, il12b-related
takayasu arteritis
  • takayasu's arteritis
tuberculosis
  • kochs disease
cysticercosis
  • taeniasis
- elite association - COSMIC cancer census association via MalaCards
Search IL12B in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

IL12B_HUMAN
  • Immunodeficiency 29 (IMD29) [MIM:614890]: A form of Mendelian susceptibility to mycobacterial disease, a rare condition caused by impairment of interferon-gamma mediated immunity. It is characterized by predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine, environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. Clinical outcome severity depends on the degree of impairment of interferon-gamma mediated immunity. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. IMD29 is characterized by undetectable IL12B secretion from leukocytes. Affected individuals generally present with BCG disease after vaccination in childhood, and at least half also have Salmonella infection. Disease phenotype is relatively mild, and patients have a good prognosis. {ECO:0000269 PubMed:11753820, ECO:0000269 PubMed:9854038}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Psoriasis 11 (PSORS11) [MIM:612599]: A common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Genatlas disease for IL12B Gene

susceptibility to BCG,non tuberculous mycobacterial and salmonella infections,with the presence of mature granulomas and a secundary impairment of IFNG production

Relevant External Links for IL12B

Genetic Association Database (GAD)
IL12B
Human Genome Epidemiology (HuGE) Navigator
IL12B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IL12B
genes like me logo Genes that share disorders with IL12B: view

Publications for IL12B Gene

  1. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. (PMID: 1673147) Wolf SF … Hewick RM (Journal of immunology (Baltimore, Md. : 1950) 1991) 2 3 4 22 60
  2. Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya. (PMID: 20350312) Zhang L … Shi YP (Malaria journal 2010) 3 22 45 60
  3. Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults. (PMID: 20387064) Phawong C … Khusmith S (Immunogenetics 2010) 3 22 45 60
  4. Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis. (PMID: 18800148) Hüffmeier U … Reis A (The Journal of investigative dermatology 2009) 3 4 45 60
  5. A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population. (PMID: 20003322) Naka I … Ohashi J (Malaria journal 2009) 3 22 45 60

Products for IL12B Gene

Sources for IL12B Gene

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