IL11RA Gene
protein-coding GIFtS: 61
GCID: GC09P034650
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|
interleukin 11 receptor, alpha
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Aliases
for IL11RA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Interleukin 11 Receptor, Alpha1 2 | | Interleukin-11 Receptor Alpha Chain2 | | IL-11 Receptor Subunit Alpha2 3 | | Interleukin-11 Receptor Subunit Alpha2 | | IL-11R Subunit Alpha2 3 | | IL-11R-Alpha1 | | CRSDA2 | | IL-11RA3 |
Export aliases for IL11RA gene to outside databasesPrevious GC identifers: GC09P034966 GC09P034820 GC09P034640 GC09P034643 |
Summaries
for IL11RA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IL11RA:
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines thatuse the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is amember of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophicfactor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domainand a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.(provided by RefSeq, Jun 2012)
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626Function: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST forinitiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/ordifferentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development ofcraniofacial bones and teeth. Restricts suture fusion and tooth number
Gene Wiki entry for IL11RA (Interleukin 11 receptor alpha subunit)
|
Genomic Views
for IL11RA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IL11RA gene promoter:
p53 AP-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for IL11RA
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL11RA |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p13 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p13IL11RA Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P034650: view genomic region
(about GC identifiers)
Start:
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34,650,699 bp from pter |
End:
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34,661,884 bp from pter |
Size:
|
11,186 bases |
Orientation:
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plus strand |
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Proteins
for IL11RA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626 (See
protein sequence)Recommended Name: Interleukin-11 receptor subunit alpha precursor Size: 422 amino acids; 45222 Da
Subunit: On ligand binding, forms a multimer complex with IL6ST/gp130
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q16542 Q5VZ80 Q7KYJ7Alternative splicing: 2 isoforms: Q14626-1 Q14626-2 (Lacks the entire cytoplasmic domain)Explore the universe of human proteins at neXtProt for IL11RA: NX_Q14626
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14626
IL11RA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001136256.1
ENSEMBL proteins: ENSP00000450565 ENSP00000450707 ENSP00000394391 ENSP00000452207 ENSP00000450543 ENSP00000368094 ENSP00000326500 ENSP00000451553 ENSP00000451447 ENSP00000450640 ENSP00000432263
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
IL11RA for ontologies About GeneDecksing
IL11RA Antibody Products:
Assay Products for IL11RA: |
Protein
Domains /
Families
for IL11RA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IL11RA for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14626ProtoNet protein and cluster: Q14626 1 Blocks protein family: IPB003530 Long hematopoietin receptor
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626Similarity: Belongs to the type I cytokine receptor family. Type 3 subfamilySimilarity: Contains 2 fibronectin type-III domainsSimilarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain |
Function
for IL11RA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626Function: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST forinitiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/ordifferentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development ofcraniofacial bones and teeth. Restricts suture fusion and tooth number Genatlas biochemistry entry for IL11RA:interleukin 11,receptor,alpha chain with two alternatively spliced forms A1,A2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): IL11RA (NM_004512) | |  | Sino Biological Human cDNA Clone for IL11RA | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL11RA | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL11RA |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL11RA |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
IL11RA for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for IL11RA: Il11ra1tm2Gos Il11ra1tm1Gos Il11ra1tm1Wehi
10 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Il11ra1):
IL11RA for phenotypes About GeneDecksing
|
Pathways & Interactions
for IL11RA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Akt Signaling | | | 2 | PEDF Induced Signaling | | | 3 | Interleukin-11 Signaling Pathway | | | 4 | Hematopoietic cell lineage | | | 5 | Jak-STAT signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IL11RA (see all 7)
1  BioSystems Pathway for IL11RA
3 
Kegg Pathways (Kegg details for IL11RA):
IL11RA for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IL11RA
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/16 Interacting proteins for IL11RA (Q146263 ENSP000003265004) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
IL11RA for ontologies About GeneDecksing
|
Drugs & Compounds
for IL11RA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
IL11RA for compounds About GeneDecksing
 Browse Tocris compounds for IL11RA
1 DrugBank Compound for IL11RA About this table
1 Novoseek chemical compound relationship for IL11RA gene About this table
Search CenterWatch for drugs/clinical trials and news about IL11RA / I11RA
|
Transcripts
for IL11RA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IL11RA gene (3 alternative transcripts): NM_001142784.2 NM_004512.3 NM_147162.1 Unigene Cluster for IL11RA: Interleukin 11 receptor, alpha Hs.591088 [show with all ESTs]Unigene Representative Sequence: BC00311015 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000555003(uc003zvi.3) ENST00000555247 ENST00000441545(uc011loq.2)
ENST00000553620 ENST00000556792 ENST00000378817(uc003zvj.3) ENST00000318041(uc003zvk.3 uc010mke.3)
ENST00000478308 ENST00000557298 ENST00000556531 ENST00000555981 ENST00000555579
ENST00000478802 ENST00000553969 ENST00000466082
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): IL11RA (NM_004512) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IL11RA | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL11RA |
Additional cDNA sequence: AK075530.1 AK292073.1 BC003110.1 BT009864.1 NR_052010.1 U32324.1 Z38102.1 Z46595.1 24/28 DOTS entries (see all 28): DT.414418 DT.416078 DT.100790058 DT.91649044 DT.40132520 DT.121165467 DT.40304433 DT.100818549 DT.65286445 DT.100745523 DT.121165543 DT.427832 DT.75103202 DT.100037339 DT.100790060 DT.100800724 DT.121165423 DT.121165518 DT.121165524 DT.429340 DT.91953599 DT.95246650 DT.95246653 DT.97804333 24/27 AceView cDNA sequences (see all 27): AI873817 R02708 AA831280 AI264000 AA514332 AI822143 BI770804 AA721361 AW581150 AI184859 BF347226 BQ710528 CD618875 AA425624 AA426233 BE262666 AW189741 AW189494 N77941 AI377039 AI970671 AA495792 CD618874 R02590
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for IL11RA (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 |
|---|
|
| SP1: | | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for IL11RA
|
Expression
for IL11RA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IL11RA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See IL11RA Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IL11RA
SOURCE GeneReport for Unigene cluster: Hs.591088
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626Tissue specificity: Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, themegakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased inprostate carcinoma
SABiosciences Expression via Pathway-Focused PCR Arrays including IL11RA:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL11RA
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IL11RA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL11RA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL11RA | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL11RA |
Orthologs
for IL11RA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IL11RA gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for IL11RA (if available)
TreeFam Gene Tree for IL11RA (if available) |
Paralogs
for IL11RA gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IL11RA gene
- ENSG000002587282 CRLF12 IL6R2 EBI32 CNTFR2
IL11RA for paralogs About GeneDecksing
|
Genomic Variants
for IL11RA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IL11RA (34650699 - 34661884 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for IL11RA
1 CNV: 9615
Human Gene Mutation Database (HGMD): IL11RA
| SABiosciences Cancer Mutation PCR Assays |
| 1 SABiosciences qBiomarker Copy Number PCR Array containing IL11RA: |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL11RA |
|
Disorders
/ Diseases
for IL11RA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IL11RA for disorders About GeneDecksing
OMIM gene information: 600939
OMIM disorders: --
UniProtKB/Swiss-Prot: I11RA_HUMAN, Q14626
Defects in IL11RA are a cause of craniosynostosis and dental anomalies (CRSDA) [MIM:614188]. CRSDA is adisorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion,delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, suchas syndactyly and/or clinodactyly
20/31  diseases for IL11RA (see all 31): About MalaCardscartilage-hair hypoplasia molluscum contagiosum megakaryocytic leukemia chronic lymphocytic leukemia
lymphocytic leukemia silicosis syndactyly cblc
craniosynostosis multiple myeloma endometrial adenocarcinoma multiple sclerosis
keloids leukemia endometrial carcinoma thrombocytopenia
acute leukemia myeloma adenocarcinoma ovarian carcinoma
1 disease from the University of Copenhagen DISEASES database for IL11RA:cartilage-hair hypoplasia 8 Novoseek disease relationships for IL11RA gene About this table
Genetic Association Database (GAD): IL11RA
Human Genome Epidemiology (HuGE) Navigator: IL11RA (11 documents)
Export disorders for IL11RA gene to outside databases
|
Publications
for IL11RA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IL11RA gene, integrated from 9 sources (see all 74):
(articles sorted by number of sources associating them with IL11RA) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11. (PubMed id 7670098)1, 2, 3 Cherel M.... Jacques Y. (1995)
- Molecular cloning and characterization of the human interleukin-11 receptor alpha-chain gene, IL11RA, located on chromosome 9p13. (PubMed id 8808281)1, 2, 9 Van Leuven F....Gossler A. (1996)
- Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma. (PubMed id 11141475)1, 2, 9 Campbell C.L.... Savarese T.M. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genetic polymorphisms of IL-1beta and IL-1 receptor antagonist in association with multiple sclerosis in Japanese patients. (PubMed id 11498264)1, 4 Niino M....Tashiro K. (2001)
- Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. British Paediatric Rheumatology Study Group. (PubMed id 11315919)1, 4 Donn R.P....Thomson W. (2001)
- Polymorphisms of the IL-1 gene complex in coal miners with silicosis. (PubMed id 11241561)1, 4 Yucesoy B....Luster M.I. (2001)
- Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells. (PubMed id 14701802)1, 9 Kiessling S....Rogler G. (2004)
- Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer. (PubMed id 14744752)1, 9 Zurita A.J....Arap W. (2004)
- Gene expression profile of cytokines and chemokines in microdissected primary Hodgkin and Reed-Sternberg (HRS) cells: high expression of interleukin-11 receptor alpha. (PubMed id 16291580)1, 9 Karube K....Harada M. (2006)
|
External Searches for IL11RA gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IL11RA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IL11RA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IL11RA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IL11RA | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/il11ra/ |
|
| | |
About This Section
| Patent Information for IL11RA gene:
Search GeneIP for patents involving IL11RA
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IL11RA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for IL11RA | | OriGene shRNA RFP for IL11RA | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IL11RA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IL11RA | | | OriGene Protein Over-expression Lysate for IL11RA | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IL11RA | | OriGene 3'-UTR Clone for IL11RA | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IL11RA | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IL11RA | | OriGene Custom Protein Services for IL11RA | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IL11RA | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IL11RA | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IL11RA | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IL11RA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IL11RA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IL11RA |
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| | | | Search Tocris compounds for IL11RA |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IL11RA |
|  |  |  | | | | Search ThermoFisher Antibodies for IL11RA |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IL11RA |
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