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Aliases for IHH Gene

Aliases for IHH Gene

  • Indian Hedgehog 2 3 5
  • Indian Hedgehog (Drosophila) Homolog 2
  • Indian Hedgehog Homolog (Drosophila) 2
  • Indian Hedgehog Homolog 3
  • Indian Hedgehog Protein 3
  • HHG-2 4
  • BDA1 3
  • HHG2 3

External Ids for IHH Gene

Previous GeneCards Identifiers for IHH Gene

  • GC02M217935
  • GC02M218640
  • GC02M219883
  • GC02M220121
  • GC02M220122
  • GC02M219744
  • GC02M219628
  • GC02M219919
  • GC02M211773

Summaries for IHH Gene

Entrez Gene Summary for IHH Gene

  • This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]

GeneCards Summary for IHH Gene

IHH (Indian Hedgehog) is a Protein Coding gene. Diseases associated with IHH include Brachydactyly, Type A1 and Acrocapitofemoral Dysplasia. Among its related pathways are Hedgehog Pathway and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and patched binding. An important paralog of this gene is SHH.

UniProtKB/Swiss-Prot for IHH Gene

  • Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).

Gene Wiki entry for IHH Gene

Additional gene information for IHH Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IHH Gene

Genomics for IHH Gene

Regulatory Elements for IHH Gene

Enhancers for IHH Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H219110 1.2 ENCODE dbSUPER 21.1 -51.8 -51766 2 ELF3 FOXA2 ATF1 MLX ARID4B THRB ZSCAN9 RAD21 RARA YY1 IHH LOC100129175 MIR375 FEV CRYBA2 LINC00608 PTPRN NHEJ1 CDK5R2 ENSG00000235024
GH02H219080 1.1 ENCODE dbSUPER 21.1 -21.4 -21443 2 FOXA2 DNMT3B ZSCAN9 RARA CREM IKZF2 THAP11 HMG20B SP5 KAT8 IHH NHEJ1 SLC23A3 LOC100129175 MIR375 PTPRN MIR153-1 RESP18 ENSG00000272644 RN7SL764P
GH02H218908 2 FANTOM5 Ensembl ENCODE dbSUPER 9.9 +150.9 150918 2 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZBTB7B CNOT9 STK36 ZNF142 USP37 AAMP OBSL1 NHEJ1 CDK5R2 ENSG00000235024 ENSG00000269068
GH02H219121 1.5 Ensembl ENCODE dbSUPER 11.6 -64.6 -64553 7 FOXA2 ATF1 ARID4B YBX1 TCF12 FOS ATF7 RUNX3 SP5 REST SLC23A3 NHEJ1 IHH LOC100129175 MIR375 FEV CRYBA2 LINC00608 RETREG2 CNPPD1
GH02H219116 1.1 ENCODE dbSUPER 12 -56.5 -56458 0 ELF3 FOXA2 MLX ARID4B THRB RAD21 YY1 SLC30A9 CREM THAP11 IHH LOC100129175 MIR375 NHEJ1 SLC23A3 RESP18 PIR54382
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IHH on UCSC Golden Path with GeneCards custom track

Genomic Location for IHH Gene

Chromosome:
2
Start:
219,054,420 bp from pter
End:
219,060,516 bp from pter
Size:
6,097 bases
Orientation:
Minus strand

Genomic View for IHH Gene

Genes around IHH on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IHH Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IHH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IHH Gene

Proteins for IHH Gene

  • Protein details for IHH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14623-IHH_HUMAN
    Recommended name:
    Indian hedgehog protein
    Protein Accession:
    Q14623
    Secondary Accessions:
    • B9EGM5
    • O43322
    • Q8N4B9

    Protein attributes for IHH Gene

    Size:
    411 amino acids
    Molecular mass:
    45251 Da
    Quaternary structure:
    • Homooligomer (indian hedgehog protein N-product). Interacts with BOC and CDON. Interacts with PTCH1.

    Three dimensional structures from OCA and Proteopedia for IHH Gene

neXtProt entry for IHH Gene

Post-translational modifications for IHH Gene

  • Cholesterylation is required for N-product targeting to lipid rafts and multimerization.
  • Palmitoylated. N-palmitoylation is required for N-product multimerization and full activity.
  • The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein and covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-terminal fragment (N-product). The N-product is the active species in both local and long-range signaling, whereas the C-product has no signaling activity (By similarity).
  • Glycosylation at posLast=282282
  • Modification sites at PhosphoSitePlus

Other Protein References for IHH Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • R&D Systems Antibodies for IHH (Indian Hedgehog/Ihh)
  • Abcam antibodies for IHH

No data available for DME Specific Peptides for IHH Gene

Domains & Families for IHH Gene

Gene Families for IHH Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted secreted proteins

Suggested Antigen Peptide Sequences for IHH Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q14623

UniProtKB/Swiss-Prot:

IHH_HUMAN :
  • The indian hedgehog protein N-product binds calcium and zinc ions; this stabilizes the protein fold and is essential for protein-protein interactions mediated by this domain.
  • Belongs to the hedgehog family.
Domain:
  • The indian hedgehog protein N-product binds calcium and zinc ions; this stabilizes the protein fold and is essential for protein-protein interactions mediated by this domain.
Family:
  • Belongs to the hedgehog family.
genes like me logo Genes that share domains with IHH: view

Function for IHH Gene

Molecular function for IHH Gene

GENATLAS Biochemistry:
Drosophila segment polarity gene,Indian hedgehog,homolog,expressed in adult kidney and liver,also expressed in osteogenic cells through the mediaton of SOX9,required for the vertebrate skeletal development
UniProtKB/Swiss-Prot Function:
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).

LifeMap Function Summary for IHH Gene

During embryonic development, IHH as signaling molecule is secreted from the following cells
It affects the following cells:

Phenotypes From GWAS Catalog for IHH Gene

Gene Ontology (GO) - Molecular Function for IHH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005113 patched binding IPI 21537345
GO:0005509 calcium ion binding IDA 21537345
GO:0008233 peptidase activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with IHH: view
genes like me logo Genes that share phenotypes with IHH: view

Human Phenotype Ontology for IHH Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for IHH Gene

MGI Knock Outs for IHH:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for IHH
  • Applied Biological Materials Clones for IHH
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for IHH Gene

Localization for IHH Gene

Subcellular locations from UniProtKB/Swiss-Prot for IHH Gene

Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. {ECO:0000250}.
Indian hedgehog protein C-product: Secreted, extracellular space. Note=The C-terminal peptide diffuses from the cell. {ECO:0000250}.
Cell membrane.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IHH gene
Compartment Confidence
plasma membrane 5
extracellular 4
golgi apparatus 3
cytoskeleton 1
nucleus 1
endoplasmic reticulum 1
lysosome 1

Gene Ontology (GO) - Cellular Components for IHH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005578 proteinaceous extracellular matrix IEA --
GO:0005615 extracellular space IEA --
GO:0005886 plasma membrane IDA,IEA 21537345
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with IHH: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for IHH Gene

Pathways & Interactions for IHH Gene

genes like me logo Genes that share pathways with IHH: view

SIGNOR curated interactions for IHH Gene

Activates:
Inactivates:
Is inactivated by:

Gene Ontology (GO) - Biological Process for IHH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001501 skeletal system development IMP 21537345
GO:0001503 ossification IEA --
GO:0001569 branching involved in blood vessel morphogenesis IEA --
GO:0001649 osteoblast differentiation IEA --
GO:0001701 in utero embryonic development IEA --
genes like me logo Genes that share ontologies with IHH: view

Drugs & Compounds for IHH Gene

(26) Drugs for IHH Gene - From: ClinicalTrials, ApexBio, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Anastrozole Approved, Investigational Pharma Aromatase inhibitor, Aromatase Inhibitors, Hormone therapy, Potent aromatase (CYP19) inhibitor 290
Methyltestosterone Approved Pharma 457
Testosterone Approved, Investigational Pharma Endogenous androgen receptor agonist 579
Cyclopamine Pharma Hedgehog (Hh) signaling Inhibitor, Inhibitor of Hedgehog (Hh) signaling 0
Anabolic Agents Pharma 527

(7) ApexBio Compounds for IHH Gene

Compound Action Cas Number
Cyclopamine Hedgehog (Hh) signaling Inhibitor 4449-51-8
GANT61 GLI antagonist 500579-04-4
GDC-0449 (Vismodegib) Hedgehog antagonist,potent and selective 879085-55-9
LY2940680 Hedgehog/SMO antagonist,inhibits Hh signaling 1258861-20-9
PF-5274857 Smo antagonist,potent and selective 1373615-35-0
Purmorphamine Hedgehog agonist 483367-10-8
SANT-1 Shh inhibitor,potent and cell-permeable 304909-07-7
genes like me logo Genes that share compounds with IHH: view

Drug Products

Transcripts for IHH Gene

mRNA/cDNA for IHH Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(30) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IHH Gene

Indian hedgehog:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for IHH
  • Applied Biological Materials Clones for IHH
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for IHH Gene

No ASD Table

Relevant External Links for IHH Gene

GeneLoc Exon Structure for
IHH
ECgene alternative splicing isoforms for
IHH

Expression for IHH Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IHH Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IHH Gene

This gene is overexpressed in Colon - Transverse (x23.8), Stomach (x7.9), and Small Intestine - Terminal Ileum (x6.4).

Protein differential expression in normal tissues from HIPED for IHH Gene

This gene is overexpressed in Plasma (54.0) and Synovial fluid (13.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IHH Gene



Protein tissue co-expression partners for IHH Gene

NURSA nuclear receptor signaling pathways regulating expression of IHH Gene:

IHH

SOURCE GeneReport for Unigene cluster for IHH Gene:

Hs.654504

mRNA Expression by UniProt/SwissProt for IHH Gene:

Q14623-IHH_HUMAN
Tissue specificity: Expressed in embryonic lung, and in adult kidney and liver.

Evidence on tissue expression from TISSUES for IHH Gene

  • Bone marrow(4.3)
  • Lung(4.1)
  • Bone(2.8)
  • Stomach(2.2)
  • Intestine(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for IHH Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • integumentary
  • respiratory
  • skeleton
Organs:
Head and neck:
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • skull
Thorax:
  • chest wall
  • clavicle
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Pelvis:
  • pelvis
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • nail
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with IHH: view

Primer Products

Orthologs for IHH Gene

This gene was present in the common ancestor of animals.

Orthologs for IHH Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IHH 33 34
  • 99.03 (n)
cow
(Bos Taurus)
Mammalia IHH 33 34
  • 91.69 (n)
oppossum
(Monodelphis domestica)
Mammalia IHH 34
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IHH 33
  • 90 (n)
mouse
(Mus musculus)
Mammalia Ihh 33 16 34
  • 88.89 (n)
rat
(Rattus norvegicus)
Mammalia Ihh 33
  • 88.73 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia IHH 34
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves IHH 33 34
  • 76.81 (n)
lizard
(Anolis carolinensis)
Reptilia IHH 34
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ihh 33
  • 68.5 (n)
African clawed frog
(Xenopus laevis)
Amphibia bhh-A-prov 33
zebrafish
(Danio rerio)
Actinopterygii ihhb 33 34
  • 64.72 (n)
ihha 34
  • 59 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta hh 34
  • 39 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 42 (a)
ManyToMany
-- 34
  • 31 (a)
ManyToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1423 33
Species where no ortholog for IHH was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IHH Gene

ENSEMBL:
Gene Tree for IHH (if available)
TreeFam:
Gene Tree for IHH (if available)

Paralogs for IHH Gene

Paralogs for IHH Gene

(2) SIMAP similar genes for IHH Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with IHH: view

Variants for IHH Gene

Sequence variations from dbSNP and Humsavar for IHH Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs121917852 Pathogenic, Brachydactyly A1 (BDA1) [MIM:112500] 219,060,185(-) ACGAG(A/G)AGAAC upstream-variant-2KB, reference, missense
rs121917853 Pathogenic, Brachydactyly A1 (BDA1) [MIM:112500] 219,057,619(-) TGACC(A/G)AGGGC reference, missense
rs121917854 Pathogenic, Brachydactyly A1 (BDA1) [MIM:112500] 219,060,168(-) GCCGA(A/C)CGCCT upstream-variant-2KB, reference, missense
rs121917856 Pathogenic, Acrocapitofemoral dysplasia (ACFD) [MIM:607778] 219,060,331(-) CGTGC(C/T)GCTCG upstream-variant-2KB, reference, missense
rs121917857 Pathogenic, Acrocapitofemoral dysplasia (ACFD) [MIM:607778] 219,057,441(-) CTCCG(C/T)CAAGT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for IHH Gene

Variant ID Type Subtype PubMed ID
nsv584491 CNV loss 21841781
nsv821902 CNV gain 20364138
nsv821903 CNV loss 20364138
nsv954840 CNV deletion 24416366

Variation tolerance for IHH Gene

Residual Variation Intolerance Score: 28.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.50; 43.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IHH Gene

Human Gene Mutation Database (HGMD)
IHH
SNPedia medical, phenotypic, and genealogical associations of SNPs for
IHH

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IHH Gene

Disorders for IHH Gene

MalaCards: The human disease database

(19) MalaCards diseases for IHH Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
brachydactyly, type a1
  • brachydactyly type a1
acrocapitofemoral dysplasia
  • acfd
brachydactyly
  • brachydactyly syndrome
craniosynostosis philadelphia type
small intestine leiomyosarcoma
  • leiomyosarcoma of the small bowel
- elite association - COSMIC cancer census association via MalaCards
Search IHH in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

IHH_HUMAN
  • Acrocapitofemoral dysplasia (ACFD) [MIM:607778]: A disorder characterized by short stature of variable severity with postnatal onset. The most constant radiographic abnormalities are observed in the tubular bones of the hands and in the proximal part of the femur. Cone-shaped epiphyses or a similar epiphyseal configuration with premature epimetaphyseal fusion result in shortening of the skeletal components involved. Cone-shaped epiphyses are also present to a variable extent at the shoulders, knees and ankles. {ECO:0000269 PubMed:12632327}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Brachydactyly A1 (BDA1) [MIM:112500]: A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. Brachydactyly type A1 is characterized by middle phalanges of all the digits rudimentary or fused with the terminal phalanges. The proximal phalanges of the thumbs and big toes are short. BDA1 inheritance is autosomal dominant. {ECO:0000269 PubMed:11455389, ECO:0000269 PubMed:12384778, ECO:0000269 PubMed:21537345}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for IHH

Genetic Association Database (GAD)
IHH
Human Genome Epidemiology (HuGE) Navigator
IHH
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IHH
genes like me logo Genes that share disorders with IHH: view

No data available for Genatlas for IHH Gene

Publications for IHH Gene

  1. Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. (PMID: 7590746) Marigo V … Seidman CE (Genomics 1995) 2 3 4 22 60
  2. Is there a role for the IHH gene in Hirschsprung's disease? (PMID: 14651602) Garcia-Barceló MM … Tam PK (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2003) 3 22 45 60
  3. A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved. (PMID: 12384778) McCready ME … Bulman DE (Human genetics 2002) 3 4 22 60
  4. Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels. (PMID: 21537345) Ma G … He L (Cell research 2011) 3 4 60
  5. Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility. (PMID: 20724312) Meulenbelt I … Slagboom PE (Annals of the rheumatic diseases 2011) 3 45 60

Products for IHH Gene

  • Addgene plasmids for IHH

Sources for IHH Gene

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