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Aliases for IGSF9B Gene

Aliases for IGSF9B Gene

  • Immunoglobulin Superfamily Member 9B 2 3 4 5
  • Immunoglobulin Superfamily, Member 9B 2
  • KIAA1030 4
  • IgSF9B 4

External Ids for IGSF9B Gene

Previous GeneCards Identifiers for IGSF9B Gene

  • GC11M133291
  • GC11M133785
  • GC11M129739

Summaries for IGSF9B Gene

GeneCards Summary for IGSF9B Gene

IGSF9B (Immunoglobulin Superfamily Member 9B) is a Protein Coding gene. GO annotations related to this gene include kinase binding. An important paralog of this gene is IGSF9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGSF9B Gene

Genomics for IGSF9B Gene

Regulatory Elements for IGSF9B Gene

Enhancers for IGSF9B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around IGSF9B on UCSC Golden Path with GeneCards custom track

Promoters for IGSF9B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around IGSF9B on UCSC Golden Path with GeneCards custom track

Genomic Location for IGSF9B Gene

133,908,302 bp from pter
133,956,985 bp from pter
48,684 bases
Minus strand

Genomic View for IGSF9B Gene

Genes around IGSF9B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGSF9B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGSF9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGSF9B Gene

Proteins for IGSF9B Gene

  • Protein details for IGSF9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein turtle homolog B
    Protein Accession:
    Secondary Accessions:
    • G5EA26

    Protein attributes for IGSF9B Gene

    1349 amino acids
    Molecular mass:
    147089 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IGSF9B Gene


neXtProt entry for IGSF9B Gene

Proteomics data for IGSF9B Gene at MOPED

Post-translational modifications for IGSF9B Gene

  • Glycosylation at Asn 241, Asn 258, and Asn 624
  • Modification sites at PhosphoSitePlus

Other Protein References for IGSF9B Gene

No data available for DME Specific Peptides for IGSF9B Gene

Domains & Families for IGSF9B Gene

Protein Domains for IGSF9B Gene

Suggested Antigen Peptide Sequences for IGSF9B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 fibronectin type-III domains.
  • Belongs to the immunoglobulin superfamily. Turtle family.
  • Contains 2 fibronectin type-III domains.
  • Contains 5 Ig-like (immunoglobulin-like) domains.
  • Belongs to the immunoglobulin superfamily. Turtle family.
genes like me logo Genes that share domains with IGSF9B: view

Function for IGSF9B Gene

Animal Model Products

  • Taconic Biosciences Mouse Models for IGSF9B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IGSF9B Gene

Localization for IGSF9B Gene

Subcellular locations from UniProtKB/Swiss-Prot for IGSF9B Gene

Cell membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for IGSF9B Gene COMPARTMENTS Subcellular localization image for IGSF9B gene
Compartment Confidence
plasma membrane 5
nucleus 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for IGSF9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030425 dendrite IEA --
genes like me logo Genes that share ontologies with IGSF9B: view

Pathways & Interactions for IGSF9B Gene

SuperPathways for IGSF9B Gene

No Data Available

Interacting Proteins for IGSF9B Gene

Gene Ontology (GO) - Biological Process for IGSF9B Gene


No data available for Pathways by source and SIGNOR curated interactions for IGSF9B Gene

Drugs & Compounds for IGSF9B Gene

No Compound Related Data Available

Transcripts for IGSF9B Gene

mRNA/cDNA for IGSF9B Gene

Unigene Clusters for IGSF9B Gene

Immunoglobulin superfamily, member 9B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IGSF9B Gene

No ASD Table

Relevant External Links for IGSF9B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGSF9B Gene

mRNA expression in normal human tissues for IGSF9B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for IGSF9B Gene

This gene is overexpressed in Frontal cortex (45.1) and Retina (23.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IGSF9B Gene

SOURCE GeneReport for Unigene cluster for IGSF9B Gene Hs.204121

genes like me logo Genes that share expression patterns with IGSF9B: view

Protein tissue co-expression partners for IGSF9B Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for IGSF9B Gene

Orthologs for IGSF9B Gene

This gene was present in the common ancestor of animals.

Orthologs for IGSF9B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IGSF9B 35
  • 89.49 (n)
  • 94.48 (a)
  • 93 (a)
(Canis familiaris)
Mammalia IGSF9B 35
  • 91.34 (n)
  • 96.01 (a)
  • 94 (a)
(Mus musculus)
Mammalia Igsf9b 35
  • 89.46 (n)
  • 96.2 (a)
Igsf9b 16
Igsf9b 36
  • 96 (a)
(Pan troglodytes)
Mammalia IGSF9B 35
  • 97.58 (n)
  • 97.52 (a)
  • 97 (a)
(Rattus norvegicus)
Mammalia Igsf9b 35
  • 89.88 (n)
  • 95.82 (a)
(Monodelphis domestica)
Mammalia IGSF9B 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia IGSF9B 36
  • 67 (a)
(Gallus gallus)
Aves IGSF9B 35
  • 81.68 (n)
  • 85.52 (a)
  • 78 (a)
(Anolis carolinensis)
Reptilia IGSF9B 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia igsf9b 35
  • 69.08 (n)
  • 75.82 (a)
(Danio rerio)
Actinopterygii igsf9bb 35
  • 70.08 (n)
  • 70.88 (a)
igsf9ba 36
  • 64 (a)
igsf9bb 36
  • 67 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13476 35
fruit fly
(Drosophila melanogaster)
Insecta CG16857 36
  • 26 (a)
tutl 36
  • 21 (a)
(Caenorhabditis elegans)
Secernentea igcm-2 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
Species with no ortholog for IGSF9B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for IGSF9B Gene

Gene Tree for IGSF9B (if available)
Gene Tree for IGSF9B (if available)

Paralogs for IGSF9B Gene

Paralogs for IGSF9B Gene

(5) SIMAP similar genes for IGSF9B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with IGSF9B: view

Variants for IGSF9B Gene

Sequence variations from dbSNP and Humsavar for IGSF9B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs558709 -- 133,939,490(+) TGTAG(C/T)AGCCA intron-variant
rs564123 -- 133,949,522(+) CAGGG(G/T)GAAAC intron-variant
rs595986 -- 133,944,296(-) TGGTA(C/T)GAGTG nc-transcript-variant, reference, synonymous-codon
rs596430 -- 133,922,126(+) ACCTA(C/T)GCGCC intron-variant
rs608048 -- 133,947,989(-) agagc(A/G)agagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IGSF9B Gene

Variant ID Type Subtype PubMed ID
nsv898472 CNV Loss 21882294
nsv826144 CNV Gain 20364138
esv2745307 CNV Deletion 23290073
esv2745309 CNV Deletion 23290073
nsv826145 CNV Loss 20364138
nsv826146 CNV Gain 20364138
esv2745310 CNV Deletion 23290073
esv275426 CNV Gain+Loss 21479260

Variation tolerance for IGSF9B Gene

Residual Variation Intolerance Score: 2.07% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.82; 58.50% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for IGSF9B Gene

Disorders for IGSF9B Gene

Relevant External Links for IGSF9B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IGSF9B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGSF9B Gene

Publications for IGSF9B Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 3 4 67
  2. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3

Products for IGSF9B Gene

Sources for IGSF9B Gene