IGSF9B Gene
protein-coding GIFtS: 39
GCID: GC11M133785
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immunoglobulin superfamily, member 9B
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Aliases
for IGSF9B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Immunoglobulin Superfamily, Member 9B1 2 | | KIAA10301 3 | | Immunoglobulin Superfamily Member 9B2 3 | | Protein Turtle Homolog B2 | | IgSF9B3 |
Export aliases for IGSF9B gene to outside databasesPrevious GC identifers: GC11M133291 GC11M129739 |
Summaries
for IGSF9B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for IGSF9B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IGSF9B gene promoter:
RREB-1 Brachyury HNF-4alpha2 Nkx2-5 Tal-1beta HNF-4alpha1 E47 Hand1 ITF-2 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for IGSF9B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF9B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q25 Ensembl cytogenetic band: 11q25 HGNC cytogenetic band: 11q25IGSF9B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M133785: view genomic region
(about GC identifiers)
Start:
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133,785,185 bp from pter |
End:
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133,826,880 bp from pter |
Size:
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41,696 bases |
Orientation:
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minus strand |
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Proteins
for IGSF9B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TUTLB_HUMAN, Q9UPX0 (See
protein sequence)Recommended Name: Protein turtle homolog B precursor Size: 1349 amino acids; 147089 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (Potential)Explore the universe of human proteins at neXtProt for IGSF9B: NX_Q9UPX0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPX0
IGSF9B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055802.1
ENSEMBL proteins: ENSP00000436552 ENSP00000436576 ENSP00000434026 ENSP00000435989 ENSP00000317980
Human Recombinant Protein Products for IGSF9B:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
IGSF9B for ontologies About GeneDecksing
IGSF9B Antibody Products:
Assay Products for IGSF9B: |
Protein
Domains /
Families
for IGSF9B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IGSF9B for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q9UPX0ProtoNet protein and cluster: Q9UPX0 UniProtKB/Swiss-Prot: TUTLB_HUMAN, Q9UPX0Similarity: Belongs to the immunoglobulin superfamily. Turtle familySimilarity: Contains 2 fibronectin type-III domainsSimilarity: Contains 5 Ig-like (immunoglobulin-like) domains |
Function
for IGSF9B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 MGI phenotypic allele  for Igsf9b (no phenotypes)
IGSF9B for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IGSF9B (NM_014987) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IGSF9B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGSF9B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9B |
|
Pathways & Interactions
for IGSF9B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGSF9B
|
Drugs & Compounds
for IGSF9B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IGSF9B
Search CenterWatch for drugs/clinical trials and news about IGSF9B / TUTLB
|
Transcripts
for IGSF9B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IGSF9B gene: NM_014987.1 Unigene Cluster for IGSF9B: Immunoglobulin superfamily, member 9B Hs.204121 [show with all ESTs]Unigene Representative Sequence: NM_0149875 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000533871(uc001qgy.1) ENST00000527648 ENST00000533160(uc001qgz.2)
ENST00000526663 ENST00000321016(uc001qgx.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IGSF9B (NM_014987) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IGSF9B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGSF9B |
Additional cDNA sequence: AB028953.1 AB231704.1 AK097578.1 AY358228.1 4 DOTS entries: DT.40245170 DT.120701381 DT.40229924 DT.40229921 8 AceView cDNA sequences: BX951897 AB028953 AY358228 AA659553 AK097578 AV733321 BF875359 AA324041
GeneLoc Exon Structure
|
Expression
for IGSF9B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IGSF9B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See IGSF9B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IGSF9B
SOURCE GeneReport for Unigene cluster: Hs.204121
SABiosciences Custom PCR Arrays for IGSF9B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF9B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IGSF9B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF9B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF9B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9B |
Orthologs
for IGSF9B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for IGSF9B gene from 4/15 species (see all 15) About this table
ENSEMBL Gene Tree for IGSF9B (if available)
TreeFam Gene Tree for IGSF9B (if available) |
Paralogs
for IGSF9B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IGSF9B gene
- IGSF92
4 SIMAP similar genes for IGSF9B using alignment to 5 protein entries: TUTLB_HUMAN (see all proteins):IGSF9 MUSK PTPRD OPCML
IGSF9B for paralogs About GeneDecksing
|
Genomic Variants
for IGSF9B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IGSF9B (133785185 - 133826880 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for IGSF9B
4 CNVs: 86093 75849 75850 75851 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF9B |
|
Disorders
/ Diseases
for IGSF9B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 IGSF9B for disorders About MalaCards
IGSF9B for disorders About GeneDecksing
OMIM gene information: 613773
OMIM disorders: --
Export disorders for IGSF9B gene to outside databases
|
Publications
for IGSF9B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IGSF9B gene integrated from 9 sources:
(articles sorted by number of sources associating them with IGSF9B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1 Clark H.F.... Gray A.M. (2003)
|
External Searches for IGSF9B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing IGSF9B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IGSF9B gene
(According to HUGE)
About This Section
| |
Specialized Databases showing IGSF9B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IGSF9B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IGSF9B gene:
Search GeneIP for patents involving IGSF9B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IGSF9B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IGSF9B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF9B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF9B | | | OriGene Protein Over-expression Lysate for IGSF9B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IGSF9B | | OriGene 3'-UTR Clone for IGSF9B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IGSF9B | | OriGene Custom Protein Services for IGSF9B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGSF9B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF9B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF9B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF9B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF9B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF9B |
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 |  |  |  | |
| | | | Search Tocris compounds for IGSF9B |
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 | | | IGSF9B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9B |
|  |  |  |  | | | | Search ThermoFisher Antibodies for IGSF9B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGSF9B |
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