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Aliases for IGSF9B Gene

Aliases for IGSF9B Gene

  • Immunoglobulin Superfamily, Member 9B 2 3
  • KIAA1030 4 6
  • Immunoglobulin Superfamily Member 9B 4
  • IgSF9B 4

External Ids for IGSF9B Gene

Previous GeneCards Identifiers for IGSF9B Gene

  • GC11M133291
  • GC11M133785
  • GC11M129739

Summaries for IGSF9B Gene

GeneCards Summary for IGSF9B Gene

IGSF9B (Immunoglobulin Superfamily, Member 9B) is a Protein Coding gene. An important paralog of this gene is IGSF9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGSF9B Gene

Genomics for IGSF9B Gene

Regulatory Elements for IGSF9B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IGSF9B Gene

133,908,302 bp from pter
133,956,985 bp from pter
48,684 bases
Minus strand

Genomic View for IGSF9B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGSF9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGSF9B Gene

Proteins for IGSF9B Gene

  • Protein details for IGSF9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein turtle homolog B
    Protein Accession:
    Secondary Accessions:
    • G5EA26

    Protein attributes for IGSF9B Gene

    1349 amino acids
    Molecular mass:
    147089 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IGSF9B Gene


neXtProt entry for IGSF9B Gene

Proteomics data for IGSF9B Gene at MOPED

Post-translational modifications for IGSF9B Gene

  • Glycosylation at Asn241, Asn258, and Asn624
  • Modification sites at PhosphoSitePlus

Other Protein References for IGSF9B Gene

Antibody Products

No data available for DME Specific Peptides for IGSF9B Gene

Domains for IGSF9B Gene

Protein Domains for IGSF9B Gene

Suggested Antigen Peptide Sequences for IGSF9B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 fibronectin type-III domains.
  • Belongs to the immunoglobulin superfamily. Turtle family.
  • Contains 2 fibronectin type-III domains.
  • Contains 5 Ig-like (immunoglobulin-like) domains.
  • Belongs to the immunoglobulin superfamily. Turtle family.
genes like me logo Genes that share domains with IGSF9B: view

Function for IGSF9B Gene

Gene Ontology (GO) - Molecular Function for IGSF9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0019900 kinase binding IEA --
genes like me logo Genes that share ontologies with IGSF9B: view

Animal Model Products

miRNA for IGSF9B Gene

miRTarBase miRNAs that target IGSF9B

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IGSF9B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for IGSF9B Gene

Localization for IGSF9B Gene

Subcellular locations from UniProtKB/Swiss-Prot for IGSF9B Gene

Cell membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for IGSF9B Gene COMPARTMENTS Subcellular localization image for IGSF9B gene
Compartment Confidence
plasma membrane 5
nucleus 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for IGSF9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030425 dendrite IEA --
GO:0043025 neuronal cell body IEA --
GO:0060077 inhibitory synapse IEA --
genes like me logo Genes that share ontologies with IGSF9B: view

Pathways for IGSF9B Gene

SuperPathways for IGSF9B Gene

No Data Available

Interacting Proteins for IGSF9B Gene

Gene Ontology (GO) - Biological Process for IGSF9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA --
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential IEA --
genes like me logo Genes that share ontologies with IGSF9B: view

No data available for Pathways by source for IGSF9B Gene

Transcripts for IGSF9B Gene

mRNA/cDNA for IGSF9B Gene

(8) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IGSF9B Gene

Immunoglobulin superfamily, member 9B:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IGSF9B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGSF9B Gene

No ASD Table

Relevant External Links for IGSF9B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGSF9B Gene

mRNA expression in normal human tissues for IGSF9B Gene

Protein differential expression in normal tissues for IGSF9B Gene

This gene is overexpressed in Frontal cortex (45.1) and Retina (23.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for IGSF9B Gene

SOURCE GeneReport for Unigene cluster for IGSF9B Gene Hs.204121

genes like me logo Genes that share expressions with IGSF9B: view

Expression partners for IGSF9B Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for IGSF9B Gene

Orthologs for IGSF9B Gene

This gene was present in the common ancestor of animals.

Orthologs for IGSF9B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IGSF9B 35
  • 89.49 (n)
  • 94.48 (a)
  • 93 (a)
(Canis familiaris)
Mammalia IGSF9B 35
  • 91.34 (n)
  • 96.01 (a)
  • 94 (a)
(Mus musculus)
Mammalia Igsf9b 35
  • 89.46 (n)
  • 96.2 (a)
Igsf9b 16
Igsf9b 36
  • 96 (a)
(Pan troglodytes)
Mammalia IGSF9B 35
  • 97.58 (n)
  • 97.52 (a)
  • 97 (a)
(Rattus norvegicus)
Mammalia Igsf9b 35
  • 89.88 (n)
  • 95.82 (a)
(Monodelphis domestica)
Mammalia IGSF9B 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia IGSF9B 36
  • 67 (a)
(Gallus gallus)
Aves IGSF9B 35
  • 81.68 (n)
  • 85.52 (a)
  • 78 (a)
(Anolis carolinensis)
Reptilia IGSF9B 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia igsf9b 35
  • 69.08 (n)
  • 75.82 (a)
(Danio rerio)
Actinopterygii igsf9bb 35
  • 70.08 (n)
  • 70.88 (a)
igsf9ba 36
  • 64 (a)
igsf9bb 36
  • 67 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13476 35
fruit fly
(Drosophila melanogaster)
Insecta CG16857 36
  • 26 (a)
tutl 36
  • 21 (a)
(Caenorhabditis elegans)
Secernentea igcm-2 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
Species with no ortholog for IGSF9B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for IGSF9B Gene

Gene Tree for IGSF9B (if available)
Gene Tree for IGSF9B (if available)

Paralogs for IGSF9B Gene

Paralogs for IGSF9B Gene

(5) SIMAP similar genes for IGSF9B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with IGSF9B: view

Variants for IGSF9B Gene

Sequence variations from dbSNP and Humsavar for IGSF9B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs91583 -- 133,947,114(-) TGCTC(A/G)CCCTC intron-variant
rs167915 -- 133,927,686(-) TACTC(A/T)CCATG intron-variant
rs191300 -- 133,930,122(-) CTGCC(A/G)CCTTA intron-variant
rs229285 -- 133,930,747(-) CCTGA(A/T)GTCCA intron-variant
rs329635 -- 133,937,924(-) TACAT(C/T)GAGGC reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for IGSF9B Gene

Variant ID Type Subtype PubMed ID
nsv898472 CNV Loss 21882294
nsv826144 CNV Gain 20364138
esv2745307 CNV Deletion 23290073
esv2745309 CNV Deletion 23290073
nsv826145 CNV Loss 20364138
nsv826146 CNV Gain 20364138
esv2745310 CNV Deletion 23290073
esv275426 CNV Gain+Loss 21479260

Relevant External Links for IGSF9B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IGSF9B Gene

Disorders for IGSF9B Gene

No disorders were found for IGSF9B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for IGSF9B Gene

Publications for IGSF9B Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 3 4
  2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for IGSF9B Gene

Sources for IGSF9B Gene

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