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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

IGSF9 Gene

protein-coding GIFtS: 47
GCID: GC01M159896

immunoglobulin superfamily, member 9

Explore 1 disease affiliated with
IGSF9 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Immunoglobulin Superfamily, Member 9¹ ²		FP18798²
IGSF9A¹ ² ³		Protein Turtle Homolog A²
KIAA1355¹ ³ ⁵		IgSF9A³
Nrt1¹ ²		NRT1³
Immunoglobulin Superfamily Member 9A² ³

External Ids:	HGNC: 18132¹	Entrez Gene: 57549²	Ensembl: ENSG00000085552⁷	OMIM: 609738⁵	UniProtKB: Q9P2J2³

Export aliases for IGSF9 gene to outside databases

Previous GC identifers: GC01M157689 GC01M155629 GC01M156674 GC01M157113 GC01M156709 GC01M158163 GC01M131253

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TUTLA_HUMAN, Q9P2J2

Function: Functions in dendrite outgrowth and synapse maturation (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IGSF9 gene promoter:
CUTL1 Nkx2-5 Tal-1beta HNF-3beta E47 GATA-1 Arnt AREB6 RSRFC4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IGSF9 promoter sequence

Search SABiosciences Chromatin IP Primers for IGSF9

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF9

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q23 Ensembl cytogenetic band: 1q23.2 HGNC cytogenetic band: 1q22-q23

IGSF9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGSF9 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M159896: view genomic region (about GC identifiers)

Start:	159,896,829 bp from pter	End:	159,915,386 bp from pter
Size:	18,558 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TUTLA_HUMAN, Q9P2J2 (See protein sequence)

Recommended Name: Protein turtle homolog A precursor

Size: 1179 amino acids; 126580 Da

Subunit: Interacts with MAGI2 and SHANK1 (By similarity)

Subcellular location: Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse (By

similarity). Note=Enriched at the excitatory synapses in mature neurons (By similarity)

Developmental stage: Expressed in a wide variety of tissues at 8 and 14 weeks of gestation

Sequence caution: Sequence=BAA92593.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for IGSF9:

1V5J (3D)

Explore the universe of human proteins at neXtProt for IGSF9: NX_Q9P2J2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9P2J2

IGSF9 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001128522.1 NP_065840.2

ENSEMBL proteins:

ENSP00000355049 ENSP00000357073

Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for IGSF9

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0030054	cell junction	IEA	--
GO:0030425	dendrite	IEA	--
GO:0045202	synapse	IEA	--

IGSF9 for ontologies About GeneDecksing

IGSF9 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for IGSF9
	Novus Biologicals IGSF9 Antibodies
	Search for Antibodies for IGSF9 at Abcam
	Uscn Antibodies for IGSF9
	Search ThermoFisher Antibodies for IGSF9

Assay Products for IGSF9:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for IGSF9
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for IGSF9

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IGSF9 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR003598 Ig_sub2

IPR007110 Ig-like_dom

IPR013783 Ig-like_fold

IPR003599 Ig_sub

IPR003961 Fibronectin_type3

Graphical View of Domain Structure for InterPro Entry Q9P2J2

ProtoNet protein and cluster: Q9P2J2

1 Blocks protein family: IPB003598 Immunoglobulin C-2 type

UniProtKB/Swiss-Prot: TUTLA_HUMAN, Q9P2J2

Domain: The PDZ-binding motif mediates interactions with MAGI2 and SHANK1 (By similarity)

Similarity: Belongs to the immunoglobulin superfamily. Turtle family

Similarity: Contains 2 fibronectin type-III domains

Similarity: Contains 5 Ig-like (immunoglobulin-like) domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TUTLA_HUMAN, Q9P2J2

Function: Functions in dendrite outgrowth and synapse maturation (By similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): IGSF9 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGSF9
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate IGSF9:
		hsa-miR-3607-3p hsa-miR-486-3p
		SwitchGear 3'UTR luciferase reporter plasmid: IGSF9 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF9 (see all 7) OriGene shRNA RFP: IGSF9 OriGene siRNA: IGSF9
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF9

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for IGSF9

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: IGSF9 (NM_014987)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGSF9
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF9

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for IGSF9
		Search LifeMap BioReagents cell lines for IGSF9

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9

Animal Models:
Mouse knock-out Igsf9^tm1Kln for IGSF9
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Igsf9):

normal

IGSF9 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for IGSF9

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for IGSF9 (Q9P2J2³ ENSP00000357073⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ASCC2	Q9H1I8³, ENSP00000305502⁴	I2D: score=4 STRING: ENSP00000305502
SART3	ENSP00000228284⁴	STRING: ENSP00000228284

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016358	dendrite development	IEA	--

IGSF9 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IGSF9
Search CenterWatch for drugs/clinical trials and news about IGSF9 / TUTLA

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IGSF9 gene (2 alternative transcripts):

NM_001135050.1 NM_020789.3

Unigene Cluster for IGSF9:

Immunoglobulin superfamily, member 9

Hs.591472 [show with all ESTs]

Unigene Representative Sequence: AK056650

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000361509(uc001fuq.2) ENST00000368094(uc001fur.2) ENST00000493195

ENST00000496645(uc001fup.2) ENST00000476102

miRNA Products:		OriGene 3'-UTR Clone (see all 2): IGSF9 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGSF9
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate IGSF9:
		hsa-miR-3607-3p hsa-miR-486-3p
		SwitchGear 3'UTR luciferase reporter plasmid: IGSF9 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF9 (see all 7) OriGene shRNA RFP: IGSF9 OriGene siRNA: IGSF9
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF9

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF9 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: IGSF9 (NM_014987)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGSF9
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF9

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF9 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat IGSF9
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF9
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF9

Additional cDNA sequence:

AB037776.1 AK056650.1 AY203932.1 AY358128.1 BC030141.2

9 DOTS entries:

DT.100776650 DT.100019556 DT.99964805 DT.100766129 DT.210991 DT.102825313 DT.95100417 DT.121427605

DT.97824360

24/1765 AceView cDNA sequences (see all 1765):

BM695091 CA406210 BM917558 BU528246 AL551487 BF218499 BM987932 BU527353

BU196771 AA359323 BE743566 BQ066807 CR607405 BQ877154 BE408544 BP368128

BG424747 BF914953 AL544512 BM832133 BQ962344 AL547597 R72048 BU849556

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for IGSF9 (see all 8) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12a	·	12b	^	13	^	14a	·	14b	^	15a	·	15b	^	16a	·	16b	·	16c	^	17a	·	17b	·
SP1:																	-																		-								-				-
SP2:													-				-																		-								-				-
SP3:																	-						-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP4:																									-										-								-
SP5:																																			-

ExUns:	17c	^	18	^	19a	·	19b	·	19c
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for IGSF9

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IGSF9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

IGSF9 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Maxillary Process

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See IGSF9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IGSF9

SOURCE GeneReport for Unigene cluster: Hs.591472

SABiosciences Custom PCR Arrays for IGSF9

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF9 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat IGSF9
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF9

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for IGSF9 gene from 4/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	IGSF9¹	immunoglobulin superfamily, member 9	65.99(n) 61.46(a)		425454 XM_423214.3 XP_423214.3
lizard (Anolis carolinensis)	Reptilia	IGSF9⁶ --	--	55(a) 17(a)	1 ↔ 1 possible ortholog	GL344498.1(935-25604) GL344575.1(6152-16522)
zebrafish (Danio rerio)	Actinopterygii	igsf9b¹	immunoglobulin superfamily, member 9b	51.99(n) 46.85(a)		553348 XM_681113.5 XP_686205.5
fruit fly (Drosophila melanogaster)	Insecta	tutl³	adult locomotory behavior	30(a)		24E1 --

ENSEMBL Gene Tree for IGSF9 (if available)
TreeFam Gene Tree for IGSF9 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for IGSF9 gene

IGSF9B²

1 SIMAP similar gene for IGSF9 using alignment to 1 protein entry: TUTLA_HUMAN:

IGSF9B

IGSF9 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2153208^1,2	C,F,A,H,	--	159897327(-)	`TGCCCG/ACCTCT`	2	--	int¹		26		NS EA NA CSA WA EU	3460
rs41264833^1,2	C,F,	--	159897328(+)	`GAGGCG/AGGCAG`	2	--	int¹		1		EU	703
rs138940739^1,2	C,	--	159897350(+)	`GAAGCC/TCTGAG`	2	--	int¹		0	--	--	--	--
rs141510647^1,2		--	159897377(+)	`GCTCAC/GATGTG`	2	--	int¹		0	--	--	--	--
rs1934074^1,2	C,F,O,A,H,	--	159897388(-)	`CTAGCG/AAGCTT`	2	--	int¹		34		MN EA NA NS WA	3504
rs189799967^1,2		--	159897421(+)	`AAGGGA/GGCAAG`	2	--	int¹		0	--	--	--	--
rs181891871^1,2		--	159897455(+)	`TGGGAA/GGCAGG`	2	--	int¹		0	--	--	--	--
rs115464963^1,2	C,F,	--	159897535(+)	`TTTCCG/AGGGGG`	2	--	int¹		1		WA	118
rs1319080^1,2	C,F,H,	--	159897559(+)	`CTCTGG/TCTCAG`	4	T P	mis¹		21		EA NA NS EU	8731
rs77570237^1,2	C,F,	--	159897638(+)	`AATTCT/CGAGTC`	4	/S	syn¹		5		WA NA EA EU	6153

HapMap Linkage Disequilibrium report for IGSF9 (159896829 - 159915386 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IGSF9: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF9

DNA2.0 Custom Variant and Variant Library Synthesis for IGSF9

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

IGSF9 for disorders           About GeneDecksing

OMIM gene information: 609738    OMIM disorders: --

1 disease for IGSF9:    About MalaCards

neuronitis

Export disorders for IGSF9 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for IGSF9 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IGSF9)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and characterization of Igsf9 in mouse and human: a new member of the immunoglobulin superfamily expressed in the developing nervous system. (PubMed id 11991715)^{1, 2, 3} Doudney K.... Stanier P. (2002)
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)^{1, 2} Nagase T.... Ohara O. (2000)
A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)¹ Clark H.F.... Gray A.M. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)¹ Bonaldo M.F.... Soares M.B. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57549	HGNC: 18132	AceView: TAGLN2andNESG1andIGSF9	Ensembl:ENSG00000085552	euGenes: HUgn57549
ECgene: IGSF9	H-InvDB: IGSF9

(According to HUGE)
About This Section

HUGE: KIAA1355

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for IGSF9	Pharmacogenomics, SNPs, Pathways

Intellectual Property for IGSF9 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for IGSF9 gene:
Search GeneIP for patents involving IGSF9

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for IGSF9
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF9		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF9
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGSF9
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF9
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF9
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF9

	GenScript Custom Purified and Recombinant Proteins Services for IGSF9		GenScript cDNA clones with any tag delivered in your preferred vector for IGSF9
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF9

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF9

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes IGSF9 gene at Home site.

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IGSF9 Gene

immunoglobulin superfamily, member 9

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IGSF9 Gene

immunoglobulin superfamily, member 9

Aliasesfor IGSF9 gene

Summariesfor IGSF9 gene

Genomic Viewsfor IGSF9 gene

Proteinsfor IGSF9 gene

Protein Domains /Familiesfor IGSF9 gene

Functionfor IGSF9 gene

Pathways & Interactionsfor IGSF9 gene

Drugs & Compoundsfor IGSF9 gene

Transcriptsfor IGSF9 gene

Expression for IGSF9 gene

Orthologsfor IGSF9 gene

Paralogsfor IGSF9 gene

Genomic Variantsfor IGSF9 gene

Disorders / Diseasesfor IGSF9 gene

Publicationsfor IGSF9 gene

External Searches for IGSF9 gene

Genome Databases showing IGSF9 gene

Other Databases showing IGSF9 gene

Specialized Databases showing IGSF9 gene

Intellectual Propertyfor IGSF9 gene

Productsfor IGSF9 gene

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Aliases
for IGSF9 gene

Summaries
for IGSF9 gene

Genomic Views
for IGSF9 gene

Proteins
for IGSF9 gene

Protein Domains /
Families
for IGSF9 gene

Function
for IGSF9 gene

Pathways & Interactions
for IGSF9 gene

Drugs & Compounds
for IGSF9 gene

Transcripts
for IGSF9 gene

Expression
for IGSF9 gene

Orthologs
for IGSF9 gene

Paralogs
for IGSF9 gene

Genomic Variants
for IGSF9 gene

Disorders / Diseases
for IGSF9 gene

Publications
for IGSF9 gene

Intellectual Property
for IGSF9 gene

Products
for IGSF9 gene