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Aliases for IGSF23 Gene

Aliases for IGSF23 Gene

  • Immunoglobulin Superfamily, Member 23 2 3

External Ids for IGSF23 Gene

Previous GeneCards Identifiers for IGSF23 Gene

  • GC19P045117

Summaries for IGSF23 Gene

Entrez Gene Summary for IGSF23 Gene

  • This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Nov 2011]

GeneCards Summary for IGSF23 Gene

IGSF23 (Immunoglobulin Superfamily, Member 23) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGSF23 Gene

Genomics for IGSF23 Gene

Genomic Location for IGSF23 Gene

44,613,590 bp from pter
44,636,781 bp from pter
23,192 bases
Plus strand

Genomic View for IGSF23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGSF23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGSF23 Gene

No data available for Regulatory Elements for IGSF23 Gene

Proteins for IGSF23 Gene

  • Protein details for IGSF23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Immunoglobulin superfamily member 23
    Protein Accession:

    Protein attributes for IGSF23 Gene

    192 amino acids
    Molecular mass:
    20591 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGSF23 Gene

Proteomics data for IGSF23 Gene at MOPED

Post-translational modifications for IGSF23 Gene

Other Protein References for IGSF23 Gene

No data available for DME Specific Peptides for IGSF23 Gene

Domains & Families for IGSF23 Gene

Gene Families for IGSF23 Gene

Protein Domains for IGSF23 Gene


Suggested Antigen Peptide Sequences for IGSF23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like (immunoglobulin-like) domain.
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with IGSF23: view

Function for IGSF23 Gene

Gene Ontology (GO) - Molecular Function for IGSF23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGSF23: view

Phenotypes for IGSF23 Gene

GenomeRNAi human phenotypes for IGSF23:
genes like me logo Genes that share phenotypes with IGSF23: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGSF23 Gene

Localization for IGSF23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for IGSF23 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for IGSF23 Gene COMPARTMENTS Subcellular localization image for IGSF23 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for IGSF23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with IGSF23: view

Pathways & Interactions for IGSF23 Gene

SuperPathways for IGSF23 Gene

No Data Available

Interacting Proteins for IGSF23 Gene

Gene Ontology (GO) - Biological Process for IGSF23 Gene


No data available for Pathways by source and SIGNOR curated interactions for IGSF23 Gene

Drugs & Compounds for IGSF23 Gene

No Compound Related Data Available

Transcripts for IGSF23 Gene

mRNA/cDNA for IGSF23 Gene

(9) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IGSF23 Gene

Immunoglobulin superfamily, member 23:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IGSF23

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGSF23 Gene

No ASD Table

Relevant External Links for IGSF23 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGSF23 Gene

mRNA expression in normal human tissues for IGSF23 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IGSF23 Gene

This gene is overexpressed in Liver (x31.9) and Small Intestine - Terminal Ileum (x5.9).

SOURCE GeneReport for Unigene cluster for IGSF23 Gene Hs.512509

genes like me logo Genes that share expression patterns with IGSF23: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IGSF23 Gene

Orthologs for IGSF23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGSF23 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IGSF23 35
  • 67.16 (n)
  • 52.94 (a)
IGSF23 36
  • 29 (a)
(Canis familiaris)
Mammalia IGSF23 35
  • 70.6 (n)
  • 59.72 (a)
IGSF23 36
  • 36 (a)
(Mus musculus)
Mammalia Igsf23 35
  • 67.63 (n)
  • 61.15 (a)
Igsf23 16
Igsf23 36
  • 38 (a)
(Pan troglodytes)
Mammalia IGSF23 35
  • 98.26 (n)
  • 97.4 (a)
IGSF23 36
  • 71 (a)
(Rattus norvegicus)
Mammalia Igsf23 35
  • 66.91 (n)
  • 56.12 (a)
Species with no ortholog for IGSF23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGSF23 Gene

Gene Tree for IGSF23 (if available)
Gene Tree for IGSF23 (if available)

Paralogs for IGSF23 Gene

No data available for Paralogs for IGSF23 Gene

Variants for IGSF23 Gene

Sequence variations from dbSNP and Humsavar for IGSF23 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs203714 -- 44,631,464(+) atgcc(G/T)gtaat intron-variant
rs203715 -- 44,634,133(+) ctacc(A/G)gctgt intron-variant
rs203716 -- 44,634,477(+) ggggg(G/T)gtatt intron-variant
rs203717 -- 44,636,512(+) CCCAA(C/T)GTAAC utr-variant-3-prime
rs366992 -- 44,634,071(+) tttac(G/T)ggggt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IGSF23 Gene

Variant ID Type Subtype PubMed ID
nsv483005 CNV Loss 15286789

Relevant External Links for IGSF23 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for IGSF23 Gene

Disorders for IGSF23 Gene

Relevant External Links for IGSF23

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with IGSF23: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGSF23 Gene

Publications for IGSF23 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  4. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington J.J. … Ducar M. (Nat. Biotechnol. 2001) 67

Products for IGSF23 Gene

Sources for IGSF23 Gene

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