Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGSF21 Gene

protein-coding   GIFtS: 48
GCID: GC01P018434

immunoglobin superfamily, member 21

 Explore 2 diseases affiliated with
IGSF21 via our new
 Human Malady Compendium 
Biological research products
for IGSF21
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Immunoglobin Superfamily, Member 211 2
MGC157301
RP11-121A23.11
Immunoglobulin Superfamily Member 212
IgSF213

External Ids:    HGNC: 282461   Entrez Gene: 849662   Ensembl: ENSG000001171547   UniProtKB: Q96ID53   

Export aliases for IGSF21 gene to outside databases

Previous GC identifers: GC01P018180 GC01P018306 GC01P016680


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IGSF21:
This gene encodes a protein which has two immunoglobulin (Ig) domains and is a member of the immunoglobulin
superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune
response pathways. (provided by RefSeq, Sep 2011)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IGSF21 gene promoter:
         Sp1   MyoD   IRF-1   Tal-1beta   AP-2gamma   E47   POU2F1   POU2F1a   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIGSF21 promoter sequence
   Search SABiosciences Chromatin IP Primers for IGSF21

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF21


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.13   Ensembl cytogenetic band:  1p36.13   HGNC cytogenetic band: 1p36.13

IGSF21 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGSF21 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P018434:  view genomic region     (about GC identifiers)

Start:
18,434,240 bp from pter      End:
18,704,979 bp from pter
Size:
270,740 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IGS21_HUMAN, Q96ID5 (See protein sequence)
Recommended Name: Immunoglobulin superfamily member 21 precursor  
Size: 467 amino acids; 51835 Da
Subcellular location: Secreted (Potential)
Secondary accessions: Q8NBR8

Explore the universe of human proteins at neXtProt for IGSF21: NX_Q96ID5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96ID5

  • IGSF21 Protein expression data from MOPED and PaxDb:    About this image 
    IGSF21 Protein Expression
    REFSEQ proteins: NP_116269.3  
    ENSEMBL proteins: 
     ENSP00000251296   ENSP00000388681  

    Human Recombinant Protein Products for IGSF21: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: IGSF21
    OriGene Custom Protein Services for IGSF21 
    GenScript Custom Purified and Recombinant Proteins Services for IGSF21
    Novus Biologicals IGSF21 Proteins
    Novus Biologicals IGSF21 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for IGSF21

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    IGSF21 for ontologies           About GeneDecksing



    IGSF21 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for IGSF21 
    GenScript Custom Superior Antibodies Services for IGSF21
    Novus Biologicals IGSF21 Antibodies
    Abcam antibodies for IGSF21 
    Uscn Antibodies for IGSF21
    Search ThermoFisher Antibodies for IGSF21

    Assay Products for IGSF21: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for IGSF21
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for IGSF21


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IGSF21 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set

    Graphical View of Domain Structure for InterPro Entry Q96ID5

    ProtoNet protein and cluster: Q96ID5

    1 Blocks protein family: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: IGS21_HUMAN, Q96ID5
    Similarity: Contains 2 Ig-like (immunoglobulin-like) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for IGSF21:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for IGSF21 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: IGSF21
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGSF21
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IGSF21:
    hsa-miR-3185
    SwitchGear 3'UTR luciferase reporter plasmidIGSF21 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF21 (see all 3)
    OriGene siRNA: IGSF21
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF21
    Sirion Biotech Custom design and validation of potent shRNA sequences against IGSF21 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IGSF21
    Sirion Biotech Customized adenovirus for overexpression of IGSF21 
    Sirion Biotech Customized adenovirus for potent knockdown of IGSF21

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IGSF21 (NM_032880)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGSF21
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF21 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for IGSF21
    Search LifeMap BioReagents cell lines for IGSF21
    Sirion Biotech Customized stable knockdown cell line services for IGSF21 
    Sirion Biotech Customized inducible knockdown cell line services for IGSF21
    Sirion Biotech Customized stable overexpressing cell line services for IGSF21
    Sirion Biotech Customized inducible overexpressing cell line services for IGSF21

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF21


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGSF21

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/46 Interacting proteins for IGSF21 (Q96ID52, 3 ENSP000002512964) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NREPQ166122, 3, ENSP000004033834MINT-64285 I2D: score=4 STRING: ENSP00000403383
    ALDH2P050912, 3MINT-63387 I2D: score=4 
    ANXA3P124292, 3MINT-63463 I2D: score=4 
    BTBD2Q9BX702, 3MINT-65389 I2D: score=4 
    ERHP840902, 3MINT-64025 I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IGSF21
    Search CenterWatch for drugs/clinical trials and news about IGSF21 / IGS21 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IGSF21 gene: 
    NM_032880.4  

    Unigene Cluster for IGSF21:

    Immunoglobin superfamily, member 21
    Hs.212511  [show with all ESTs]
    Unigene Representative Sequence: NM_032880
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000251296(uc001bau.2) ENST00000412684 ENST00000497331(uc001bav.2)
    ENST00000473951

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: IGSF21
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGSF21
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IGSF21:
    hsa-miR-3185
    SwitchGear 3'UTR luciferase reporter plasmidIGSF21 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF21 (see all 3)
    OriGene siRNA: IGSF21
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF21
    Sirion Biotech Custom design and validation of potent shRNA sequences against IGSF21 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IGSF21 (NM_032880)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGSF21
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF21 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF21
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IGSF21
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF21
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF21

    Additional cDNA sequence: 

    AK075316.1 AK294121.1 BC007618.1 

    4 DOTS entries:

    DT.215471  DT.101977213  DT.91902680  DT.95176500 

    24/98 AceView cDNA sequences (see all 98):

    BU727314 BQ068297 AK092618 BM710418 T33909 R52319 AX747631 D51740 
    BF346623 AA363868 BC007618 BI758183 F04956 CR593587 CR610302 D51951 
    BE674731 AL536512 AW157772 AI681322 AI589300 H49512 AL565578 BG818356 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for IGSF21 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12
    SP1:              -                       -     -                 -     -                                 
    SP2:                                                              -     -                                 
    SP3:                                      -     -                                                         
    SP4:                                                                                                      
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for IGSF21

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IGSF21 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TATCGCTGCA
    IGSF21 Expression
    About this image

    IGSF21 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    10/11 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 11
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerMature Rod Bipolar CellsBipolar, Retina
    Spinal CordSpinal Dorsal ColumnsDorsal Spinal Cord Progenitor CellsSpinal Cord
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainCerebral CortexBrain
    BrainHypothalamusBrain
    BrainMedulla OblongataBrain
    BrainThalamusBrain
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Spinal CordSpinal Dorsal ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    ES04(HES-4) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See IGSF21 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IGSF21

    SOURCE GeneReport for Unigene cluster: Hs.212511
        SABiosciences Custom PCR Arrays for IGSF21
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF21
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IGSF21
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF21
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF21
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF21

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IGSF21 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Igsf211 , 5 immunoglobin superfamily, member 215
    immunoglobulin superfamily, member 211
    87.72(n)1
    94.43(a)1
      4 (71.09 cM)5
    2308681  NM_198610.21  NP_941012.11 
     1400268465 
    chicken
    (Gallus gallus)
    Aves IGSF211 immunoglobin superfamily, member 21 76.88(n)
    84.23(a)
      419359  XM_417520.3  XP_417520.3 
    lizard
    (Anolis carolinensis)
    Reptilia IGSF216
    --
    78(a)
    1 ↔ 1
    GL344239.1(40530-66449)
    zebrafish
    (Danio rerio)
    Actinopterygii BI428490.12   -- 76.26(n)    BI428490.1 


    ENSEMBL Gene Tree for IGSF21 (if available)
    TreeFam Gene Tree for IGSF21 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IGSF21 gene

    IGSF21 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for IGSF21
    PGOHUM00000242833


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5453 NCBI SNPs in IGSF21 are shown (see all 5453    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs801680391,2
    F--16678884(+) GGGAGC/AGCAGC 1 -- us2k11Minor allele frequency- A:0.10WA 118
    rs28837631,2
    H--16679519(+) TCAGGT/GGAACG 1 -- us2k14Minor allele frequency- G:0.00NS EA 420
    rs740562841,2
    C--16679563(+) CCTTCC/TGGGGT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs747516571,2
    F--16680251(+) TGGCTG/AGATCC 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1126803141,2
    C--16680959(+) AGAACC/TGCGGC 1 -- ut510--------
    rs740562861,2
    C--16682124(+) GAGCCG/CCACTG 1 -- int11Minor allele frequency- C:0.50WA 2
    rs360829601,2
    C,F--16682616(+) GAATGC/TGCAGA 1 -- int15Minor allele frequency- T:0.06NA EA 246
    rs38062941,2
    C,F,H--16682777(+) TCCTGA/GCGCCT 1 -- int15Minor allele frequency- G:0.05EA NS 1706
    rs38202781,2
    C,F--16682877(+) GCCTCG/TGAGCT 1 -- int12Minor allele frequency- T:0.04NA EA 240
    rs792008641,2
    --16682973(+) CAGCCG/AGGAGC 1 -- int11Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for IGSF21 (18434240 - 18684240 bp, first 250kb of IGSF21)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for IGSF21
         1 CNV: 4213
         2 Indels: 74394 84107

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF21
    DNA2.0 Custom Variant and Variant Library Synthesis for IGSF21

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IGSF21 for disorders           About GeneDecksing

    2 diseases for IGSF21:    About MalaCards
    prostate cancer    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: IGSF21 (2 documents)

    Export disorders for IGSF21 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IGSF21 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with IGSF21)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    5. Genome-wide meta-analysis for severe diabetic retinop athy. (PubMed id 21441570)1 Grassi M.A....Nicolae D.L. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Genome-wide association study to identify single nucl eotide polymorphisms (SNPs) associated with the development of erectile dysfunc tion in African-American men after radiotherapy for prostate cancer. (PubMed id 20932654)1 Kerns S.L....Rosenstein B.S. (2010)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    9. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84966 HGNC: 28246 AceView: MGC15730 Ensembl:ENSG00000117154 euGenes: HUgn84966
    ECgene: IGSF21 H-InvDB: IGSF21

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IGSF21 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IGSF21 gene:
    Search GeneIP for patents involving IGSF21

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   Browse OriGene shRNA RFPs  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGSF21   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGSF21  
     OriGene Protein Over-expression Lysate for IGSF21   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for IGSF21   OriGene 3'-UTR Clone for IGSF21  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGSF21  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for IGSF21   OriGene Custom Protein Services for IGSF21  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGSF21
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGSF21
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF21
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGSF21
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGSF21
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGSF21
     GenScript Custom Purified and Recombinant Proteins Services for IGSF21 GenScript cDNA clones with any tag delivered in your preferred vector for IGSF21
     GenScript Custom Assay Services for IGSF21 GenScript Custom Superior Antibodies Services for IGSF21
     GenScript Custom overexpressing Cell Line Services for IGSF21 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in IGSF21 promoter
     Search Chromatin IP Primers for IGSF21
     RT2 qPCR Primer Assay in human, mouse, rat IGSF21
     Search GNC Networks for IGSF21
     SABiosciences Custom PCR Arrays for IGSF21
     Search Tocris compounds for IGSF21
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     IGSF21 antibodies
     IGSF21 proteins
     IGSF21 lysates
     Antibodies for IGSF21
     See all of Abcam's Antibodies, Kits and Proteins for IGSF21
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     IGSF21 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for IGSF21
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGSF21
     SwitchGear 3'UTR luciferase reporter plasmids for IGSF21
     SwitchGear Promoter luciferase reporter plasmids for IGSF21
     Search ThermoFisher Antibodies for IGSF21
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGSF21
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for IGSF21
    Sirion Biotech Customized:
     stable knockdown cell line services for IGSF21
     inducible knockdown cell line services for IGSF21
     design and validation of potent shRNA sequences against IGSF21
     adenovirus for potent knockdown of IGSF21
     adenovirus for overexpression of IGSF21
     stable overexpressing cell line services for IGSF21
     inducible overexpressing cell line services for IGSF21
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      IGSF21 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4