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IGSF11 Gene

protein-coding   GIFtS: 51
GCID: GC03M118619

Immunoglobulin Superfamily, Member 11

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Immunoglobulin Superfamily, Member 111 2     Igsf132
Cancer/Testis Antigen 1191 2     Brain And Testis-Specific Immunoglobin Superfamily Protein2
Brain And Testis-Specific Immunoglobulin Superfamily Protein2 3     CXADR Like 12
CXADRL12 3     Immunoglobulin Superfamily Member 112
VSIG32 3     V-Set And Immunoglobulin Domain Containing 32
V-Set And Immunoglobulin Domain-Containing Protein 32 3     BTIGSF3
BT-IgSF2     Bt-IGSF3
CT1192     IgSF113

External Ids:    HGNC: 166691   Entrez Gene: 1524042   Ensembl: ENSG000001448477   OMIM: 6083515   UniProtKB: Q5DX213   

Export aliases for IGSF11 gene to outside databases

Previous GC identifers: GC03M118248 GC03M119900 GC03M119941 GC03M119940 GC03M120102 GC03M115994


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IGSF11 Gene:
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It
shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial
cell-selective adhesion molecule (ESAM).(supplied by OMIM, Apr 2005)

GeneCards Summary for IGSF11 Gene:
IGSF11 (immunoglobulin superfamily, member 11) is a protein-coding gene. An important paralog of this gene is CLMP.

UniProtKB/Swiss-Prot: IGS11_HUMAN, Q5DX21
Function: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IGSF11 gene promoter:
         RFX1   Nkx2-2   NF-E2 p45   PPAR-gamma1   POU2F1a   PPAR-gamma2   Zic3   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): IGSF11 promoter sequence
   Search Chromatin IP Primers for IGSF11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IGSF11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.32   Ensembl cytogenetic band:  3q13.32   HGNC cytogenetic band: 3q21.2

IGSF11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGSF11 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M118619:  view genomic region     (about GC identifiers)

Start:
118,619,404 bp from pter      End:
118,864,915 bp from pter
Size:
245,512 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IGS11_HUMAN, Q5DX21 (See protein sequence)
Recommended Name: Immunoglobulin superfamily member 11 precursor  
Size: 431 amino acids; 46120 Da
Miscellaneous: The last 20 cytoplasmic amino acids are not required for the cell adhesion function
Secondary accessions: C9JZN0 Q8N4F1 Q8N7T8 Q8NDD2
Alternative splicing: 3 isoforms:  Q5DX21-1   Q5DX21-2   Q5DX21-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IGSF11: NX_Q5DX21

Explore proteomics data for IGSF11 at MOPED

Post-translational modifications: 

  • N-glycosylated (By similarity)1
  • Glycosylation2 at Asn102
  • Modification sites at PhosphoSitePlus

  • See IGSF11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001015887.1  NP_689751.2  

    ENSEMBL proteins: 
     ENSP00000406092   ENSP00000377370   ENSP00000420486   ENSP00000401240   ENSP00000417413  
     ENSP00000418976   ENSP00000418047   ENSP00000346700  

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    antibodies-online proteins for IGSF11 (4 products) 

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ISET: Immunoglobulin superfamily / I-set domain containing

    5 InterPro protein domains:
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q5DX21

    ProtoNet protein and cluster: Q5DX21

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: IGS11_HUMAN, Q5DX21
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    Find genes that share domains with IGSF11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IGS11_HUMAN, Q5DX21
    Function: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with IGSF11           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Igsf11 (no phenotypes)

    Find genes that share phenotypes with IGSF11           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for IGSF11

    miRNA
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    Block miRNA regulation of human, mouse, rat IGSF11 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IGSF11 (see all 42):
    hsa-miR-579 hsa-miR-548j hsa-miR-548l hsa-miR-105 hsa-miR-183* hsa-miR-186 hsa-miR-548d-5p hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidIGSF11 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IGS11_HUMAN, Q5DX21: Cell membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with IGSF11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IGSF11
    Interactions:

        Search GeneGlobe Interaction Network for IGSF11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for IGSF11 (ENSP000003773704) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PVRL4ENSP000003569914STRING: ENSP00000356991
    IGHEENSP000003749834STRING: ENSP00000374983
    LYZENSP000002612674STRING: ENSP00000261267
    VSIG2ENSP000003186844STRING: ENSP00000318684
    SIGLEC8ENSP000003210774STRING: ENSP00000321077
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0040008regulation of growth IEA--

    Find genes that share ontologies with IGSF11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IGSF11 (IGS11)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IGSF11 gene (2 alternative transcripts): 
    NM_001015887.1  NM_152538.2  

    Unigene Cluster for IGSF11:

    Immunoglobulin superfamily, member 11
    Hs.112873  [show with all ESTs]
    Unigene Representative Sequence: NM_152538
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000425327(uc010hqs.3) ENST00000393775(uc003ebw.3 uc011biv.2 uc003ebx.3)
    ENST00000489689 ENST00000441144 ENST00000491903 ENST00000459718 ENST00000483401
    ENST00000480431 ENST00000494802 ENST00000354673(uc003eby.3 uc003ebz.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate IGSF11 (see all 42):
    hsa-miR-579 hsa-miR-548j hsa-miR-548l hsa-miR-105 hsa-miR-183* hsa-miR-186 hsa-miR-548d-5p hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidIGSF11 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat IGSF11
      QuantiFast Probe-based Assays in human, mouse, rat IGSF11

    Additional mRNA sequence: 

    AB071618.1 AB079879.1 AK097667.1 AK122611.1 AK292387.1 AK296503.1 AL834256.1 AY358141.1 
    BC034411.1 

    11 DOTS entries:

    DT.95160966  DT.100024483  DT.100774024  DT.101980278  DT.95357812  DT.120855668  DT.40216326  DT.91850170 
    DT.95369526  DT.92000939  DT.99987669 

    Selected AceView cDNA sequences (see all 88):

    T16562 BM671028 BX105148 BU739288 BE221680 AL834256 CA841780 AI074710 
    CA842074 BX510100 AA490144 F09720 N92664 N92661 AA453957 AA453456 
    BU149128 AB079879 AX781653 BE221674 N27451 BE327853 R59790 AA918479 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for IGSF11    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
    SP1:        -     -                             -                           
    SP2:        -     -                                                         
    SP3:                                                                        
    SP4:                                            -                           


    ECgene alternative splicing isoforms for IGSF11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IGSF11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACACTGAAAA
    IGSF11 Expression
    About this image


    IGSF11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Endothelium (Cardiovascular System)
             Extraembryonic Angioblasts Extraembryonic Capillary Plexus
     
     Extraembryonic Mesoderm (Extraembryonic Tissues)
             Extraembryonic Angioblasts Extraembryonic Capillary Plexus
     
     Testis (Reproductive System)
    IGSF11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IGSF11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.112873

    UniProtKB/Swiss-Prot: IGS11_HUMAN, Q5DX21
    Tissue specificity: Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal
    muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IGSF11 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Igsf111 , 5 immunoglobulin superfamily, member 111, 5 86.37(n)1
    89.02(a)1
      16 (26.87 cM)5
    2076831  NM_170599.21  NP_733548.21 
     389014715 
    chicken
    (Gallus gallus)
    Aves IGSF111 immunoglobulin superfamily, member 11 73.59(n)
    75.36(a)
      418346  XM_416568.4  XP_416568.3 
    lizard
    (Anolis carolinensis)
    Reptilia IGSF116
    immunoglobulin superfamily, member 11
    74(a)
    1 ↔ 1
    3(180483798-180505501)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia igsf111 immunoglobulin superfamily, member 11 63.16(n)
    62.6(a)
      100489577  XM_002936235.2  XP_002936281.1 
    zebrafish
    (Danio rerio)
    Actinopterygii igsf111 immunoglobulin superfamily member 11 64.69(n)
    67.33(a)
      100004469  NM_001278822.1  NP_001265751.1 


    ENSEMBL Gene Tree for IGSF11 (if available)
    TreeFam Gene Tree for IGSF11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IGSF11 gene
    CLMP2  ESAM2  VSIG82  GPA332  VSIG12  CXADR2  VSIG22  C1orf2042  
    6 SIMAP similar genes for IGSF11 using alignment to 6 protein entries:     IGS11_HUMAN (see all proteins):
    CD7    IGKV A18    GPA33    ESAM    VSIG2    CXADR

    Find genes that share paralogs with IGSF11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IGSF11 (see all 4713)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1869693131,2
    Cuntested1118646351(+) ATCCCC/TGACTT 2 -- int10--------
    rs671151341,2
    C--116236589(+) AAAAA-/AA/AAA
            
    GTGTC
    1 -- int11NA 2
    rs347859341,2
    C,F--118619070(+) AGGAAG/TGATCC 2 -- ds50013Minor allele frequency- T:0.33NA 6
    rs1808474381,2
    --118619111(+) TAACTC/TGACTT 2 -- ds50010--------
    rs1865197641,2
    --118619194(+) TTCAGC/TGGTGA 2 -- ds50010--------
    rs729668521,2
    C,F--118619247(+) GGAAAT/AGGGAA 2 -- ds50012Minor allele frequency- A:0.03WA 120
    rs1913302281,2
    --118619257(+) AAATAC/GCTCAA 2 -- ds50010--------
    rs1817017231,2
    --118619268(+) TGTATA/GAAGAA 2 -- ds50010--------
    rs1859557751,2
    --118619298(+) TATGGA/GTAAGA 2 -- ds50010--------
    rs757836501,2
    C--118619534(+) AATGCA/CAGATA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for IGSF11 (118619404 - 118864915 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IGSF11 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725820CNV Deletion23290073
    esv271379CNV Insertion20981092
    nsv3960CNV Insertion18451855
    esv25249CNV Loss19812545
    nsv822226CNV Loss20364138
    nsv3961CNV Loss18451855
    nsv829692CNV Loss17160897
    nsv523926CNV Gain19592680
    dgv618n27CNV Gain19166990
    nsv470860CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608351    OMIM disorders: --


    Find genes that share disorders with IGSF11           About GenesLikeMe

    Genetic Association Database (GAD): IGSF11

    Export disorders for IGSF11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IGSF11 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with IGSF11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. BT-IgSF, a novel immunoglobulin superfamily protein, functions as a cell adhesion molecule. (PubMed id 15795899)1, 2, 9 Harada H.... Okada S. (J. Cell. Physiol. 2005)
    2. IGSF11 gene, frequently up-regulated in intestinal-type gastric cancer, encodes adhesion molecule homologous to CXADR, FLJ22415 and ESAM. (PubMed id 12851705)1, 2, 9 Katoh M. and Katoh M. (Int. J. Oncol. 2003)
    3. Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. (PubMed id 16108831)1, 2, 9 Watanabe T.... Nakamura Y. (Cancer Sci. 2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Molecular cloning of a novel immunoglobulin superfamily gene preferentially expressed by brain and testis. (PubMed id 12207903)1, 3 Suzu S....Motoyoshi K. (Biochem. Biophys. Res. Commun. 2002)
    6. Gene network analysis in a pediatric cohort identifies novel lung function genes. (PubMed id 24023788)1 Ong B.A....Hakonarson H. (PLoS ONE 2013)
    7. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). (PubMed id 22952603)1 Hart A.B....Palmer A.A. (PLoS ONE 2012)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. A secreted protein microarray platform for extracellular protein interaction discovery. (PubMed id 21982860)1 Ramani S.R....Gonzalez L.C. (Anal. Biochem. 2012)
    10. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 152404 HGNC: 16669 AceView: IGSF11 Ensembl:ENSG00000144847 euGenes: HUgn152404
    ECgene: IGSF11 H-InvDB: IGSF11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IGSF11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IGSF11 gene:
    Search GeneIP for patents involving IGSF11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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