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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGSF10 Gene

protein-coding   GIFtS: 49
GCID: GC03M151143

Immunoglobulin Superfamily, Member 10

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Immunoglobulin Superfamily, Member 101 2
Calvaria Mechanical Force Protein 6082 3
CMF6082 3
Immunoglobulin Superfamily Member 102
IgSF103

External Ids:    HGNC: 263841   Entrez Gene: 2853132   Ensembl: ENSG000001525807   UniProtKB: Q6WRI03   

Export aliases for IGSF10 gene to outside databases

Previous GC identifers: GC03M152476 GC03M152637 GC03M148533


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IGSF10 Gene: 
IGSF10 (immunoglobulin superfamily, member 10) is a protein-coding gene. Diseases associated with IGSF10 include sjogren's syndrome, and multiple sclerosis. An important paralog of this gene is NCAM2.

UniProtKB/Swiss-Prot: IGS10_HUMAN, Q6WRI0
Function: May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IGSF10 gene promoter:
         AML1a   FOXD1   Olf-1   Tal-1beta   Meis-1b   E47   MEF-2A   aMEF-2   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): IGSF10 promoter sequence
   Search SABiosciences Chromatin IP Primers for IGSF10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGSF10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q25.1

IGSF10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGSF10 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M151143:  view genomic region     (about GC identifiers)

Start:
151,143,172 bp from pter      End:
151,176,497 bp from pter
Size:
33,326 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IGS10_HUMAN, Q6WRI0 (See protein sequence)
Recommended Name: Immunoglobulin superfamily member 10 precursor  
Size: 2623 amino acids; 290838 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=BAC05429.1; Type=Erroneous initiation;
Secondary accessions: Q86YJ9 Q8N772 Q8NA84
Alternative splicing: 3 isoforms:  Q6WRI0-1   Q6WRI0-2   Q6WRI0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IGSF10: NX_Q6WRI0

Explore proteomics data for IGSF10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6WRI0

  • IGSF10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IGSF10 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001171616.1  NP_001171617.1  NP_849144.2  

    ENSEMBL proteins: 
     ENSP00000417627   ENSP00000282466  

    Human Recombinant Protein Products for IGSF10: 
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    Cloud-Clone Corp. Proteins for IGSF10 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    IGSF10 for ontologies           About GeneDecksing



    IGSF10 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ISET: Immunoglobulin superfamily / I-set domain containing

    5/8 InterPro protein domains (see all 8):
     IPR003598 Ig_sub2
     IPR000483 Cys-rich_flank_reg_C
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR003591 Leu-rich_rpt_typical-subtyp

    Graphical View of Domain Structure for InterPro Entry Q6WRI0

    ProtoNet protein and cluster: Q6WRI0

    3 Blocks protein domains:
    IPB000372 Cysteine-rich flanking region
    IPB000483 Cysteine-rich flanking region
    IPB003599 Immunoglobulin subtype


    UniProtKB/Swiss-Prot: IGS10_HUMAN, Q6WRI0
    Similarity: Contains 12 Ig-like C2-type (immunoglobulin-like) domains
    Similarity: Contains 6 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 LRRNT domain


    IGSF10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IGS10_HUMAN, Q6WRI0
    Function: May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    IGSF10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for IGSF10:
     Increased gamma-H2AX phosphory  Metaphase cells 

    Animal Models:
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    Gene Editing
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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGSF10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for IGSF10 (ENSP000002824664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLA2G2DENSP000003642464STRING: ENSP00000364246
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001503ossification IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--

    IGSF10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IGSF10 (IGS10)

    1 DrugBank Compound for IGSF10    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Pyridoxal PhosphateCodecarboxylase (see all 9)54-47-7targetcofactor17139284 17016423 10592235

    Search CenterWatch for drugs/clinical trials and news about IGSF10 / IGS10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IGSF10 gene (3 alternative transcripts): 
    NM_001178145.1  NM_001178146.1  NM_178822.4  

    Unigene Cluster for IGSF10:

    Immunoglobulin superfamily, member 10
    Hs.58561  [show with all ESTs]
    Unigene Representative Sequence: NM_178822
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000489791 ENST00000497472 ENST00000282466(uc011bob.2 uc011boc.2 uc011bod.2)
    ENST00000493841 ENST00000495443
    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate IGSF10 (see all 13):
    hsa-miR-647 hsa-miR-519d hsa-miR-20a hsa-miR-106a hsa-miR-106b hsa-miR-519e hsa-miR-182 hsa-miR-548t
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Additional mRNA sequence: 

    AK093069.1 AK098838.1 AK128160.1 AY273815.1 BC031063.1 BC045734.1 

    3 DOTS entries:

    DT.40128724  DT.99993706  DT.441996 

    24/48 AceView cDNA sequences (see all 48):

    H89283 BU607959 NM_178822 AW513013 AA236364 AA453870 AA256881 BM681303 
    BX282231 AY273815 CA390554 CA432806 BM993418 BM684722 AX747900 BQ030329 
    AK093069 AA255475 AK128160 BU679993 AI685041 BC031063 BM930084 H89282 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for IGSF10    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c
    SP1:                                -     -     -                     
    SP2:                                            -                     
    SP3:                                                                  


    ECgene alternative splicing isoforms for IGSF10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IGSF10 expression in normal human tissues (normalized intensities)      IGSF10 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAAATAAAA
    IGSF10 Expression
    About this image


    IGSF10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Blood Brain Barrier (Nervous System)
             Postnatal Endothelial Cells Blood Brain Barrier
     
     Limb (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Endothelium (Cardiovascular System)
             Postnatal Endothelial Cells Blood Brain Barrier
     
     Bone (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Cartilage (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod

    See IGSF10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IGSF10

    SOURCE GeneReport for Unigene cluster: Hs.58561
        SABiosciences Custom PCR Arrays for IGSF10
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for IGSF10 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Igsf101 , 5 immunoglobulin superfamily, member 101, 5 76.24(n)1
    66.05(a)1
      3 (29.03 cM)5
    2420501  NM_001162884.11  NP_001156356.11 
     593167355 
    chicken
    (Gallus gallus)
    Aves IGSF101 immunoglobulin superfamily, member 10 65.17(n)
    62.61(a)
      425035  XM_422837.3  XP_422837.3 
    lizard
    (Anolis carolinensis)
    Reptilia IGSF106
    immunoglobulin superfamily, member 10
    46(a)
    1 ↔ 1
    3(17950284-17977236)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003294561 immunoglobulin superfamily member 10-like 56.92(n)
    52.56(a)
      100329456  XM_002664516.2  XP_002664562.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Strn-Mlck6
    Stretchin-Mlck
    4(a)
    1 → many
    2R(11834431-11873458)
    worm
    (Caenorhabditis elegans)
    Secernentea ketn-16
    F21C10.76
    Protein F21C10.7
    8(a)
    10(a)
    many ↔ many
    many ↔ many
    V(2781483-2801027)
    V(9112790-9122180)


    ENSEMBL Gene Tree for IGSF10 (if available)
    TreeFam Gene Tree for IGSF10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IGSF10 gene
    NCAM22  DSCAM2  ENSG000002154282  DSCAML12  MXRA52  NCAM12  
    1 SIMAP similar gene for IGSF10 using alignment to 2 protein entries:     IGS10_HUMAN (see all proteins):
    MXRA5

    IGSF10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/783 SNPs in IGSF10 are shown (see all 783)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0321864
    ----see VAR_0321862 H Y mis40--------
    VAR_0321854
    ----see VAR_0321852 R W mis40--------
    rs1396953231,2
    F--151154975(+) GGGATT/CCCATC 6 /G syn11Minor allele frequency- C:0.00NA 4536
    rs1114684131,2
    C,F--151155001(+) TGATAG/AAGATT 6 /L syn13Minor allele frequency- A:0.01CSA WA NA 4652
    rs1823803021,2
    C--151155038(+) GGTGCA/GTAGGT 6 Y syn10--------
    rs1123007371,2
    C,F--151155044(+) TAGGTA/GAGAAT 6 L syn12Minor allele frequency- G:0.01NA EU 5851
    rs1450369311,2
    C,F--151155090(+) TCTCAA/GTATAG 6 T I mis11Minor allele frequency- G:0.00NA 4540
    rs1112547901,2
    C,F--151155095(+) ATATAG/ACCAAC 6 /G syn12Minor allele frequency- A:0.01NA EU 5867
    rs1381650001,2
    C,F--151155132(+) TTCCTG/ACATCC 6 /A /V mis11Minor allele frequency- A:0.00NA 4526
    rs1411482041,2
    C,F--151155169(+) AGAACC/TATTGC 6 S G mis11Minor allele frequency- T:0.00NA 4540

    HapMap Linkage Disequilibrium report for IGSF10 (151143172 - 151176497 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for IGSF10:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv273729CNV Insertion20981092
    nsv508960CNV Insertion20534489
    nsv4063CNV Insertion18451855
    nsv829757CNV Loss17160897
    nsv877649CNV Loss21882294
    nsv877650CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing IGSF10
    DNA2.0 Custom Variant and Variant Library Synthesis for IGSF10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for IGSF10:    About MalaCards
    sjogren's syndrome    multiple sclerosis


    IGSF10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IGSF10

    Export disorders for IGSF10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IGSF10 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with IGSF10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    4. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
    5. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. CMF608 -- a novel mechanical strain-induced bone-specific protein expressed in early osteochondroprogenitor cells. (PubMed id 14962803)2 Segev O....Feinstein E. (2004)
    9. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (2000)
    10. ESIMS--an ongoing clinical trial in secondary progressive multiple sclerosis. (PubMed id 11188776)9 Hommes O.R. and Maas-Enriquez M. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 285313 HGNC: 26384 AceView: IGSF10 Ensembl:ENSG00000152580 euGenes: HUgn285313
    ECgene: IGSF10 H-InvDB: IGSF10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IGSF10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IGSF10 gene:
    Search GeneIP for patents involving IGSF10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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