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Aliases for IGLV7-43 Gene

Aliases for IGLV7-43 Gene

  • Immunoglobulin Lambda Variable 7-43 2 3 5
  • IGLV743 3
  • V3-2 3

External Ids for IGLV7-43 Gene

Previous GeneCards Identifiers for IGLV7-43 Gene

  • GC22U990128
  • GC22P021073
  • GC22P021079
  • GC22P022749

Summaries for IGLV7-43 Gene

GeneCards Summary for IGLV7-43 Gene

IGLV7-43 (Immunoglobulin Lambda Variable 7-43) is a Protein Coding gene. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Immune System. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGLV3-12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLV7-43 Gene

Genomics for IGLV7-43 Gene

Regulatory Elements for IGLV7-43 Gene

Enhancers for IGLV7-43 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around IGLV7-43 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGLV7-43 Gene

Chromosome:
22
Start:
22,395,018 bp from pter
End:
22,395,489 bp from pter
Size:
472 bases
Orientation:
Plus strand

Genomic View for IGLV7-43 Gene

Genes around IGLV7-43 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGLV7-43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGLV7-43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGLV7-43 Gene

Proteins for IGLV7-43 Gene

  • Protein details for IGLV7-43 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U2
    Recommended name:
    Protein IGLV7-43
    Protein Accession:
    A0A0B4J1U2

    Protein attributes for IGLV7-43 Gene

    Size:
    117 amino acids
    Molecular mass:
    12451 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGLV7-43 Gene

Proteomics data for IGLV7-43 Gene at MOPED

Post-translational modifications for IGLV7-43 Gene

No Post-translational modifications

Other Protein References for IGLV7-43 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGLV7-43 Gene

Domains & Families for IGLV7-43 Gene

Gene Families for IGLV7-43 Gene

Protein Domains for IGLV7-43 Gene

Suggested Antigen Peptide Sequences for IGLV7-43 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGLV7-43: view

No data available for UniProtKB/Swiss-Prot for IGLV7-43 Gene

Function for IGLV7-43 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLV7-43 Gene

Localization for IGLV7-43 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGLV7-43 Gene

Pathways & Interactions for IGLV7-43 Gene

genes like me logo Genes that share pathways with IGLV7-43: view

Interacting Proteins for IGLV7-43 Gene

Gene Ontology (GO) - Biological Process for IGLV7-43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 6091030
GO:0006956 complement activation TAS --
genes like me logo Genes that share ontologies with IGLV7-43: view

No data available for SIGNOR curated interactions for IGLV7-43 Gene

Drugs & Compounds for IGLV7-43 Gene

No Compound Related Data Available

Transcripts for IGLV7-43 Gene

mRNA/cDNA for IGLV7-43 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGLV7-43 Gene

No ASD Table

Relevant External Links for IGLV7-43 Gene

GeneLoc Exon Structure for
IGLV7-43
ECgene alternative splicing isoforms for
IGLV7-43

Expression for IGLV7-43 Gene

mRNA expression in normal human tissues for IGLV7-43 Gene

mRNA differential expression in normal tissues according to GTEx for IGLV7-43 Gene

This gene is overexpressed in Spleen (x15.5), Small Intestine - Terminal Ileum (x7.8), Colon - Transverse (x7.6), Minor Salivary Gland (x6.1), and Whole Blood (x4.3).

Protein differential expression in normal tissues from HIPED for IGLV7-43 Gene

This gene is overexpressed in Skin (62.5) and Urine (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGLV7-43 Gene



genes like me logo Genes that share expression patterns with IGLV7-43: view

Protein tissue co-expression partners for IGLV7-43 Gene

- Elite partner

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGLV7-43 Gene

Orthologs for IGLV7-43 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGLV7-43 Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 62 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 33 (a)
ManyToMany
Species with no ortholog for IGLV7-43:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGLV7-43 Gene

ENSEMBL:
Gene Tree for IGLV7-43 (if available)
TreeFam:
Gene Tree for IGLV7-43 (if available)

Paralogs for IGLV7-43 Gene

Pseudogenes.org Pseudogenes for IGLV7-43 Gene

genes like me logo Genes that share paralogs with IGLV7-43: view

Variants for IGLV7-43 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for IGLV7-43 Gene

Disorders for IGLV7-43 Gene

No disorders were found for IGLV7-43 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGLV7-43 Gene

Publications for IGLV7-43 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 67
  2. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PMID: 9074928) Kawasaki K. … Shimizu N. (Genome Res. 1997) 3
  3. First genomic sequence of a human Ig variable lambda gene belonging to subgroup I. Functional genes, pseudogenes and vestigial sequences are interspersed in the IGLV locus. (PMID: 2499871) Alexandre D. … Lefranc M.P. (Nucleic Acids Res. 1989) 3
  4. The isolation of a human Ig V lambda gene from a recombinant library of chromosome 22 and estimation of its copy number. (PMID: 6091030) Anderson M.L.M. … Young B.D. (Nucleic Acids Res. 1984) 3
  5. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3

Products for IGLV7-43 Gene

Sources for IGLV7-43 Gene

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