IGLV6-57 Gene
protein-coding GIFtS : 27 GCID: GC22 P022550
immunoglobulin lambda variable 6-57
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Aliasesfor IGLV6-57 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Immunoglobulin Lambda Variable 6-57 1 2 IGLV6572 V1-222
Export aliases for IGLV6-57 gene to outside databases Previous GC identifers: GC22U990130 GC22P020874 GC22P020881
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Summariesfor IGLV6-57 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor IGLV6-57 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000022.10 NC_018933.1 NT_011520.12 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for IGLV6-57 Other transcription factors Search SABiosciences Chromatin IP Primers for IGLV6-57 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLV6-57
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q11.2 Ensembl cytogenetic band: 22q11.22 HGNC cytogenetic band: 22q11.2 IGLV6-57 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22P022550: view genomic region
(about GC identifiers )
Start: 22,550,113 bp from pter End:
22,550,686 bp from pter
Size: 574 bases Orientation:
plus strand
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Proteinsfor IGLV6-57 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/TrEMBL: Q5NV88 See
protein sequence )Recommended Name: Size : 98 amino acids; 10643 DaIGLV6-57 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374820 Human Recombinant Protein Products: IGLV6-57 Antibody Products: Assay Products for IGLV6-57:
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Protein
Domains /for IGLV6-57 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q5NV88 ProtoNet protein and cluster: Q5NV88
1 Blocks protein family : IPB003596
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Functionfor IGLV6-57 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor IGLV6-57 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGLV6-57
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Drugs & Compoundsfor IGLV6-57 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for IGLV6-57 IGLV6-57
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Transcriptsfor IGLV6-57 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Clusters for IGLV6-57:
Immunoglobulin lambda variable 6-57 Hs.535668 [show with all ESTs ] , Hs.734039 [show with all ESTs ] Unigene Representative Sequences: BQ898761 , CB956063 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390285 Additional cDNA sequence: AB064028.1 AF047249.1 AF047250.1 AF047251.1 AF047252.1 AF047254.1 AF047255.1 AF047256.1 AF047257.1 AF047258.1 AF047259.1 AF047260.1 AF047265.1 AF047266.1 AF054649.1 AF054650.1 AF054651.1 AF054652.1 AF054653.1 AF054654.1 AF060128.1 AF063699.1 AF063725.1 AF063733.1 AF063770.1 AF063776.1 AF103665.1 AF103712.1 AF103724.1 AF115356.1 AF115357.1 AF115358.1 AF115359.1 AF121762.1 AF124180.1 AF124181.1 AF124182.1 AF124183.1 AF124184.1 AF124185.1 AF124188.1 AF124190.1 AF267874.1 AF267875.1 AF320837.1 AF320838.1 AF320839.1 AF320840.1 AF320841.1 AF320842.1 AF462643.1 AF462650.1 AF462661.1 AF462663.1 AF462671.1 AF462676.1 AF462678.1 AF462681.1 AF462687.1 AJ241381.1 AJ241392.1 AJ241410.1 AJ241413.1 AJ276098.1 AJ306837.1 AJ410919.1 AJ496503.1 AM184006.1 AM184007.1 AM184066.1 AM259148.1 AY942015.1 AY942058.1 AY942084.1 AY957514.1 AY998673.1 DQ322775.1 EF589404.1 EF589415.1 EF589451.1 EF589460.1 EF589528.1 EF589534.1 EF589537.1 EF589545.1 EF589550.1 EF589553.1 EF710786.1 EF710787.1 EF710788.1 EF710789.1 EF710790.1 EF710791.1 EF710792.1 EF710793.1 EF710794.1 EF710795.1 EF710796.1 EF710797.1 EF710798.1 EF710811.1 EF710812.1 EF710813.1 EF710814.1 EF710842.1 EF710843.1 EF710844.1 EF710845.1 EF710878.1 EF710879.1 EF710880.1 EF710881.1 EF710882.1 EF710883.1 EF710884.1 EF710885.1 EF710886.1 EF710887.1 EF710888.1 EF710889.1 EF710890.1 EF710891.1 EF710892.1 EF710946.1 EF710947.1 EF710948.1 EF710949.1 EF710950.1 EF710951.1 EF710952.1 EF710953.1 EF710954.1 EF710969.1 EF710970.1 EF710971.1 EF710972.1 EF710973.1 EF710974.1 EF710975.1 EF710976.1 EF710977.1 EF710978.1 EF710979.1 EF710980.1 EF710984.1 EF710985.1 EF710986.1 EF710987.1 EF710988.1 EF710989.1 EF710990.1 EF710991.1 EF710992.1 EF710993.1 EF711003.1 EF711004.1 EF711005.1 EF711024.1 EF711025.1 EF711026.1 EF711037.1 EF711038.1 EF711039.1 EF711040.1 EF711041.1 EF711042.1 EF711043.1 EF711044.1 EF711045.1 EF711053.1 EF711054.1 EF711055.1 EF711056.1 EF711057.1 EF711078.1 EF711079.1 EF711080.1 EU599343.1 EU599346.1 FJ172996.1 FJ172997.1 FJ385526.1 HQ172114.1 HQ172140.1 HQ172142.1 HQ890345.1 JQ301911.1 L41061.2 U76686.1 X57772.1 X98219.1
14 DOTS entries : DT.95149053 DT.100031781 DT.100046820 DT.92051583 DT.100885141 DT.95329771 DT.87014838 DT.95363020
DT.100885124 DT.120676955 DT.120677340 DT.99936046 DT.95363078 DT.120678077 7 AceView cDNA sequences :
BC023973 AF267874 AF462676 AF063699 AF060128 AF103724 AF047252 GeneLoc Exon Structure
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Expression for IGLV6-57 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IGLV6-57 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAGATAATCA
About this image See IGLV6-57 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IGLV6-57 SOURCE GeneReport for Unigene clusters: Hs.535668 Hs.734039 SABiosciences Custom PCR Arrays for IGLV6-57 Primer Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat IGLV6-57 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLV6-57 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLV6-57
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Orthologsfor IGLV6-57 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for IGLV6-57 gene from 1/2 species (see all 2 ) About this table
ENSEMBL Gene Tree for IGLV6-57 (if available)TreeFam Gene Tree for IGLV6-57 (if available)
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Paralogsfor IGLV6-57 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IGLV6-57 gene IGLV3-12 2 IGLV2-18 2 IGLV3-19 2 IGLV1-51 2 IGLV9-49 2 IGLV3-22 2 IGLV2-23 2 IGLV8-61 2 IGLV4-60 2 IGLV1-47 2 IGLV2-14 2 IGLV2-33 2 IGLV3-32 2 IGLV5-52 2 IGLV1-44 2 IGLV3-21 2 IGLV2-11 2 IGLV3-10 2 IGLV3-9 2 IGLV5-37 2 IGLV1-50 2 VPREB3 2 IGLV3-25 2 IGLV2-8 2 IGLV10-54 2 IGLV7-43 2 IGLV5-45 2 IGLV3-27 2 IGLV7-46 2 IGLV1-40 2 IGLV11-55 2 IGLV5-48 2 IGLV3-1 2 IGLV4-3 2 VPREB1 2 IGLV3-16 2 IGLV4-69 2 IGLV1-36 2 About GeneDecksing
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Genomic Variantsfor IGLV6-57 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor IGLV6-57 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing 2 : About MalaCards congenital diaphragmatic hernia hernia Export disorders for IGLV6-57 gene to outside databases
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Publicationsfor IGLV6-57 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for IGLV6-57 gene integrated from 9 sources :(articles sorted by number of sources associating them with IGLV6-57) Utopia : connect your pdf to the dynamic
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 (2002) Recognition of immunoglobulins by Fcgamma receptors. (PubMed id 11955599) 1 (2002) One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PubMed id 9074928) 1 (1997) Sequence and evolution of the human germline V lambda repertoire. (PubMed id 8951372) 1 (1996) Activation of C1r by proteolytic cleavage. (PubMed id 1249422) 1 (1976) Physicochemical and functional characterization of the C1r subunit of the first complement component. (PubMed id 814163) 1 (1976)
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External Searches for IGLV6-57 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing IGLV6-57 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing IGLV6-57 gene
(According to HUGE )
About This Section --
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Specialized Databases showing IGLV6-57 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for IGLV6-57 Pharmacogenomics, SNPs, Pathways IMGT entry for IGLV6-57The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for IGLV6-57 gene: IGLV6-57 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IGLV6-57 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGLV6-57 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGLV6-57 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLV6-57 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLV6-57 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLV6-57 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLV6-57
Search ThermoFisher Antibodies for IGLV6-57
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLV6-57
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