Aliases for IGLV4-3 Gene
External Ids for IGLV4-3 Gene
- HGNC: 5919
- Entrez Gene: 28786
- Ensembl: ENSG00000211672
Previous GeneCards Identifiers for IGLV4-3 Gene
- GC22U990138
- GC22P021538
- GC22P021108
- GC22P021294
- GC22P021543
- GC22P023213
Summaries for IGLV4-3 Gene
GeneCards Summary for IGLV4-3 Gene
IGLV4-3 (Immunoglobulin Lambda Variable 4-3) is a Protein Coding gene. An important paralog of this gene is IGLV3-12.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLV4-3 Gene
Genomics for IGLV4-3 Gene
Regulatory Elements for IGLV4-3 Gene
Enhancers for IGLV4-3 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around IGLV4-3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for IGLV4-3 Gene
- Chromosome:
- 22
- Start:
- 22,871,507 bp from pter
- End:
- 22,872,035 bp from pter
- Size:
- 529 bases
- Orientation:
- Plus strand
Genomic View for IGLV4-3 Gene
Genes around IGLV4-3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.22 by Ensembl
- 22q11.2 by Entrez Gene
- 22q11.2 by HGNC
IGLV4-3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGLV4-3 Gene
Proteins for IGLV4-3 Gene
-
Protein details for IGLV4-3 Gene (UniProtKB/TrEMBL)
- Protein Symbol:
- A0A075B6K6
- Recommended name:
- Protein IGLV4-3
- Protein Accession:
- A0A075B6K6
Protein attributes for IGLV4-3 Gene
- Size:
- 122 amino acids
- Molecular mass:
- 13330 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for IGLV4-3 Gene
No Post-translational modifications
Other Protein References for IGLV4-3 Gene
- ENSEMBL proteins:
Antibody Products
- Search GeneTex for Antibodies for IGLV4-3
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGLV4-3
- Origene Custom Protein Services for IGLV4-3
- Search GeneTex for Proteins for IGLV4-3
- Abcam proteins for IGLV4-3
Assay Products
No data available for DME Specific Peptides for IGLV4-3 Gene
Domains & Families for IGLV4-3 Gene
Gene Families for IGLV4-3 Gene
Protein Domains for IGLV4-3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for IGLV4-3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for IGLV4-3 Gene
Function for IGLV4-3 Gene
Phenotypes for IGLV4-3 Gene
- GenomeRNAi human phenotypes for IGLV4-3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for IGLV4-3
CRISPR Products
- Browse CRISPR knockouts for IGLV4-3
miRNA Products
- Search ViGene Biosciences for IGLV4-3
Inhibitory RNA Products
- Search ViGene Biosciences for IGLV4-3
Cell Line Products
- Search ViGene Biosciences for IGLV4-3
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLV4-3 Gene
Localization for IGLV4-3 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGLV4-3 Gene
More details on SuperPathways for IGLV4-3Transcripts for IGLV4-3 Gene
mRNA/cDNA for IGLV4-3 Gene
- (97) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for IGLV4-3
miRNA Products
- Search ViGene Biosciences for IGLV4-3
Inhibitory RNA Products
- Search ViGene Biosciences for IGLV4-3
Flow Cytometry Products
Expression for IGLV4-3 Gene
mRNA differential expression in normal tissues according to GTEx for IGLV4-3 Gene
This gene is overexpressed in Spleen (x13.7), Colon - Transverse (x8.1), Small Intestine - Terminal Ileum (x7.9), Minor Salivary Gland (x5.5), and Whole Blood (x4.3).
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IGLV4-3 Gene
Orthologs for IGLV4-3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | -- 36 |
|
OneToMany | |
| -- 36 |
|
OneToMany | |||
| -- 36 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 36 |
|
ManyToMany | |
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 36 |
|
ManyToMany | |
| -- 36 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 36 |
|
OneToMany |
- Species with no ortholog for IGLV4-3:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for IGLV4-3 Gene
Paralogs for IGLV4-3 Gene
- IGLV3-12 5
- IGLV1-40 5
- IGLV1-50 5
- IGLV11-55 5
- IGLV7-43 5
- IGLV1-36 5
- IGLV1-44 5
- IGLV9-49 5
- IGLV3-19 5
- VPREB3 5
- IGLV5-37 5
- IGLV8-61 5
- IGLV3-16 5
- IGLV1-47 5
- IGLV3-32 5
- IGLV3-9 5
- IGLV2-18 5
- IGLV3-25 5
- IGLV2-23 5
- IGLV5-48 5
- IGLV2-14 5
- IGLV5-52 5
- IGLV3-22 5
- IGLV3-10 5
- VPREB1 5
- IGLV10-54 5
- IGLV1-51 5
- IGLV2-11 5
- IGLV4-69 5
- IGLV3-21 5
- IGLV3-1 5
- IGLV4-60 5
- IGLV2-8 5
- IGLV3-27 5
- IGLV7-46 5
- IGLV2-33 5
- IGLV5-45 5
- IGLV6-57 5
(87) SIMAP similar genes for IGLV4-3 Gene using alignment to 1 proteins:
- IGLV4-69
- IGLV4-60
- VLC8
- V5-2
- VPREB1
- IGLV5-37
- IGLV1-44
- V4-4
- V4-3
- V1-18
- V1-17
- IGLV5-45
- IGLV3-25
- IGLV2-23
- HuC4lambda Vlambda
- V2-13
- IGLV2-11
- IGLV1-40
- V2-1
- V1-2
- VKA17
- V2-6
- V1-19
- IGLV3-16
- IGLV2-18
- IGLV11-55
- IGLV3-19
- IGL@
- VL4
- V<lambda>3
- V2-7
- V2-14
- IGLV3-27
- IGLV3-12
- VL3L
- V<kappa>1
- V1-4
- V1-11
- IgLC-rG
- IGLV1-36
- HuD11lambda Vlambda
- DKFZp686E23209
- V1-22
- IGLV8-61
- IGKV1-5
- scFv
- VH
- V<kappa>3
- IGLV3-22
- DKFZp686O01196
- DKFZp686C15213
- SDNK1
- VL1
- HuVH8B VH
- A30
- VL87-2
- VH3
- IGHV
- HEL180
- BV05S1J2.1
- TRGV9
- VHCH1
- IGLV7-43
- IGLV2-33
- DKFZp686G11190
- VPREB3
- IGLV
- VL6
- VHC8
- TCRBV5S1A1T
- DKFZp686O16217
- IGKV4-1
- VH-7 family (N54P3)D/J
- TCRBV6S5A2
- IGLV10-54
- DKFZp686M08189
- IGK@
- IGH@
- VK3
- VH-3 family (VH26.)D/J
- IGLV7-46
- IGKV A18
- TCRBV23S1A2T
- VH-3 family (VH26)D/J
- TRA@
- TCRBV5S6A3N2T
- DKFZp781M0386
Pseudogenes.org Pseudogenes for IGLV4-3 Gene
Variants for IGLV4-3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for IGLV4-3 Gene
Disorders for IGLV4-3 Gene
Relevant External Links for IGLV4-3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- IGLV4-3
No disorders were found for IGLV4-3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGLV4-3 Gene
Publications for IGLV4-3 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 67
- Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3
- One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PMID: 9074928) Kawasaki K. … Shimizu N. (Genome Res. 1997) 3
- Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
- Activation of C1r by proteolytic cleavage. (PMID: 1249422) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
Products for IGLV4-3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IGLV4-3
- Origene Custom Protein Services for IGLV4-3
- Browse OriGene Inhibitory RNA Products For IGLV4-3
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for IGLV4-3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Custom all cDNA clones Services for IGLV4-3
- GenScript Custom Purified and Recombinant Proteins Services for IGLV4-3
- GenScript Custom Assay Services for IGLV4-3
- GenScript Custom overexpressing Cell Line Services for IGLV4-3
- Browse GenScript CRISPR for IGLV4-3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IGLV4-3
- Novus Biologicals proteins and lysates for IGLV4-3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search ViGene Biosciences for IGLV4-3
- Search ViGene Biosciences for IGLV4-3
- Search ViGene Biosciences for IGLV4-3
- Search ViGene Biosciences for IGLV4-3
Sources for IGLV4-3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon