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IGLV4-3 Gene(Protein Coding)

Immunoglobulin Lambda Variable 4-3

GCID:
GC22P022871
GIFtS:
21
Genes Participants
UDN Logo

Aliases for IGLV4-3 Gene

Aliases for IGLV4-3 Gene

  • Immunoglobulin Lambda Variable 4-3 2 3 5
  • IGLV43 3
  • V5-1 3

External Ids for IGLV4-3 Gene

Previous GeneCards Identifiers for IGLV4-3 Gene

  • GC22U990138
  • GC22P021538
  • GC22P021108
  • GC22P021294
  • GC22P021543
  • GC22P023213

Summaries for IGLV4-3 Gene

GeneCards Summary for IGLV4-3 Gene

IGLV4-3 (Immunoglobulin Lambda Variable 4-3) is a Protein Coding gene. An important paralog of this gene is IGLV4-69.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLV4-3 Gene

Genomics for IGLV4-3 Gene

Products:

  1. Regulatory Element

Regulatory Elements for IGLV4-3 Gene

Enhancers for IGLV4-3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F022871 0.5 ENCODE 0.8 -0.3 -331 0.2 CTCF ZBTB7A SPI1 IGLV4-3 IGLV3-4
GH22F022863 0.9 Ensembl ENCODE 0.4 -5.6 -5557 4.1 KLF17 UBTF MNT RELA ZNF121 ATF3 ZBTB48 ZNF366 POLR2A TARDBP IGLV3-4 IGLV4-3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IGLV4-3 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGLV4-3 Gene

Chromosome:
22
Start:
22,871,507 bp from pter
End:
22,872,035 bp from pter
Size:
529 bases
Orientation:
Plus strand

Genomic View for IGLV4-3 Gene

Genes around IGLV4-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGLV4-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGLV4-3 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for IGLV4-3 Gene

Proteins for IGLV4-3 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for IGLV4-3 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6K6
    Recommended name:
    Protein IGLV4-3
    Protein Accession:
    A0A075B6K6

    Protein attributes for IGLV4-3 Gene

    Size:
    122 amino acids
    Molecular mass:
    13330 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGLV4-3 Gene

Post-translational modifications for IGLV4-3 Gene

No Post-translational modifications

Other Protein References for IGLV4-3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGLV4-3 Gene

Domains & Families for IGLV4-3 Gene

Gene Families for IGLV4-3 Gene

HGNC:

Protein Domains for IGLV4-3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IGLV4-3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGLV4-3: view

No data available for UniProtKB/Swiss-Prot for IGLV4-3 Gene

Function for IGLV4-3 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Phenotypes for IGLV4-3 Gene

GenomeRNAi human phenotypes for IGLV4-3:
genes like me logo Genes that share phenotypes with IGLV4-3: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLV4-3 Gene

Localization for IGLV4-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGLV4-3 Gene

Pathways & Interactions for IGLV4-3 Gene

SuperPathways for IGLV4-3 Gene

PathCards logo More details on SuperPathways for IGLV4-3
No Data Available

Interacting Proteins for IGLV4-3 Gene

Gene Ontology (GO) - Biological Process for IGLV4-3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for IGLV4-3 Gene

Drugs & Compounds for IGLV4-3 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for IGLV4-3 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for IGLV4-3 Gene

(97) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGLV4-3 Gene

No ASD Table

Relevant External Links for IGLV4-3 Gene

GeneLoc Exon Structure for
IGLV4-3
ECgene alternative splicing isoforms for
IGLV4-3

Expression for IGLV4-3 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGLV4-3 Gene

mRNA expression in normal human tissues for IGLV4-3 Gene
mRNA expression by BioGPS for IGLV4-3 GenemRNA expression by GTEx for IGLV4-3 Gene

mRNA differential expression in normal tissues according to GTEx for IGLV4-3 Gene

This gene is overexpressed in Spleen (x13.7), Colon - Transverse (x8.1), Small Intestine - Terminal Ileum (x7.9), Minor Salivary Gland (x5.5), and Whole Blood (x4.3).
genes like me logo Genes that share expression patterns with IGLV4-3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IGLV4-3 Gene

Orthologs for IGLV4-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGLV4-3 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
 Mammalia -- 35
  • 72 (a)
 OneToMany
-- 35
  • 69 (a)
 OneToMany
-- 35
  • 68 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 35
  • 69 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
oppossum
(Monodelphis domestica)
 Mammalia -- 35
  • 56 (a)
 ManyToMany
-- 35
  • 53 (a)
 ManyToMany
-- 35
  • 53 (a)
 ManyToMany
-- 35
  • 51 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
-- 35
  • 50 (a)
 ManyToMany
-- 35
  • 49 (a)
 ManyToMany
-- 35
  • 48 (a)
 ManyToMany
-- 35
  • 48 (a)
 ManyToMany
-- 35
  • 48 (a)
 ManyToMany
-- 35
  • 47 (a)
 ManyToMany
-- 35
  • 47 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 46 (a)
 ManyToMany
-- 35
  • 45 (a)
 ManyToMany
-- 35
  • 45 (a)
 ManyToMany
-- 35
  • 45 (a)
 ManyToMany
-- 35
  • 45 (a)
 ManyToMany
-- 35
  • 44 (a)
 ManyToMany
-- 35
  • 44 (a)
 ManyToMany
-- 35
  • 44 (a)
 ManyToMany
-- 35
  • 44 (a)
 ManyToMany
-- 35
  • 44 (a)
 ManyToMany
-- 35
  • 41 (a)
 ManyToMany
lizard
(Anolis carolinensis)
 Reptilia -- 35
  • 41 (a)
 OneToMany
Species where no ortholog for IGLV4-3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGLV4-3 Gene

ENSEMBL:
Gene Tree for IGLV4-3 (if available)
TreeFam:
Gene Tree for IGLV4-3 (if available)

Paralogs for IGLV4-3 Gene

Paralogs for IGLV4-3 Gene

(87) SIMAP similar genes for IGLV4-3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for IGLV4-3 Gene

genes like me logo Genes that share paralogs with IGLV4-3: view

Variants for IGLV4-3 Gene

Relevant External Links for IGLV4-3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGLV4-3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGLV4-3 Gene

Disorders for IGLV4-3 Gene

Relevant External Links for IGLV4-3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IGLV4-3

No disorders were found for IGLV4-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGLV4-3 Gene

Publications for IGLV4-3 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PMID: 9074928) Kawasaki K. … Shimizu N. (Genome Res. 1997) 3 64
  4. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3 64
  5. Activation of C1r by proteolytic cleavage. (PMID: 1249422) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3 64

Products for IGLV4-3 Gene

Sources for IGLV4-3 Gene

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