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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGLV3-25 Gene

protein-coding   GIFtS: 28
GCID: GC22P023029

immunoglobulin lambda variable 3-25
  Search for IGLV3-25
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for IGLV3-25    

Aliases
for IGLV3-25 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Immunoglobulin Lambda Variable 3-251 2
V2-172 4
IGLV3252

External Ids:    HGNC: 59081   Entrez Gene: 287932   Ensembl: ENSG000002116597   UniProtKB: Q5NV904   

Export aliases for IGLV3-25 gene to outside databases

Previous GC identifers: GC22U990145 GC22P021354 GC22P021301 GC22P021359


Summaries
for IGLV3-25 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for IGLV3-25 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011520.12  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for IGLV3-25
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for IGLV3-25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLV3-25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.2   Ensembl cytogenetic band:  22q11.22   HGNC cytogenetic band: 22q11.2

IGLV3-25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGLV3-25 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P023029:  view genomic region     (about GC identifiers)

Start:
 23,029,190 bp from pter      End:
 23,029,745 bp from pter
Size:
 556 bases      Orientation:
 plus strand

Proteins
for IGLV3-25 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/TrEMBL: Q5NV90 (See protein sequence)
Recommended Name: V2-17 protein  
Size: 97 amino acids; 10405 Da

IGLV3-25 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).


ENSEMBL proteins: 
 ENSP00000374840  
Reactome Protein details: Q5NV90
Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom Protein Services for IGLV3-25 
GenScript Custom Purified and Recombinant Proteins Services for IGLV3-25
Novus Biologicals IGLV3-25 Protein
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Browse Proteins at Uscn


IGLV3-25 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
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OriGene Custom Antibody Services for IGLV3-25 
GenScript Custom Superior Antibodies Services for IGLV3-25
Search for Antibodies for IGLV3-25 at Abcam  
Browse Antibodies at Uscn
Search ThermoFisher Antibodies for IGLV3-25

Assay Products for IGLV3-25: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for IGLV3-25
Browse Enzo Life Sciences for kits & assays
Browse ELISAs and CLIAs at Uscn

Protein Domains /
Families
for IGLV3-25 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
IGLV3-25 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR007110 Ig-like_dom
 IPR003596 Ig_V-set_subgr
 IPR013783 Ig-like_fold
 IPR013106 Ig_V-set

Graphical View of Domain Structure for InterPro Entry Q5NV90

ProtoNet protein and cluster: Q5NV90

1 Blocks protein family: IPB003596 Immunoglobulin V-type


Function
for IGLV3-25 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
miRNA
Products:    		Browse 3'-UTR reporter clones for miRNA target validation
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGLV3-25
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate IGLV3-25
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLV3-25

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for IGLV3-25

Clone
Products:     		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for IGLV3-25
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLV3-25
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLV3-25 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for IGLV3-25
Search LifeMap BioReagents cell lines for IGLV3-25

In Situ Assay
Products:   
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGLV3-25


Pathways & Interactions
for IGLV3-25 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Cleavage of Alpha-1-Microglobulin
8/11 pathways (see all 11)
Cleavage of Alpha-1-Microglobulin1.00
FCGR activation0.65
Binding and Uptake of Ligands by Scavenger Receptors0.79
Initial triggering of complement0.60
Scavenging of Heme from Plasma0.79
Role of phospholipids in phagocytosis0.53
Classical antibody-mediated complement activation0.74
Complement cascade0.47
2Immune System
Immune System1.00
Innate Immune System0.46
Adaptive Immune System0.59
3Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation1.00
Fcgamma receptor (FCGR) dependent phagocytosis0.80
Role of myosins in phagosome formation0.80

Pathway sources
See GeneCards unified pathways
Show all pathways


5/17        Reactome Pathways for IGLV3-25 (see all 17)
    Role of myosins in phagosome formation
FCGR activation
Cleavage of Alpha-1-Microglobulin
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts
Role of phospholipids in phagocytosis



IGLV3-25 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGLV3-25

Drugs & Compounds
for IGLV3-25 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IGLV3-25
Search CenterWatch for drugs/clinical trials and news about IGLV3-25 

Transcripts
for IGLV3-25 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for IGLV3-25:

Immunoglobulin lambda variable 3-25
Hs.449585  [show with all ESTs]
Unigene Representative Sequence: AK057174
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000390305

miRNA
Products:     		Browse 3'-UTR reporter clones for miRNA target validation
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGLV3-25
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate IGLV3-25
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLV3-25
Clone
Products:     		Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for IGLV3-25
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLV3-25
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLV3-25 
Primer
Products:    		Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat IGLV3-25
  Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLV3-25
  Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLV3-25

Additional cDNA sequence: 

AB063972.1 AB063973.1 AB063976.1 AB063978.1 AB063979.1 AB063988.1 AB063990.1 AB064000.1 
AB064008.1 AB064012.1 AB064013.1 AB064015.1 AB064017.1 AB064020.1 AB064027.1 AB064030.1 
AB064036.1 AB064142.1 AB064143.1 AB064147.1 AB064151.1 AB064154.1 AB064155.1 AB064157.1 
AB064159.1 AB064165.1 AB064167.1 AB064169.1 AB064172.1 AB064177.1 AB064180.1 AB064181.1 
AB064182.1 AB064183.1 AB064185.1 AB064187.1 AB064190.1 AB064199.1 AB064201.1 AB064204.1 
AB064206.1 AB064211.1 AB064216.1 AB064218.1 AB064219.1 AB064226.1 AB064227.1 AB064231.1 
AB064232.1 AB064234.1 AB087878.1 AB363345.1 AB363347.1 AB363353.1 AB363354.1 AB363357.1 
AB363358.1 AB363359.1 AB363361.1 AB363364.1 AB363365.1 AB649271.1 AF026919.1 AF026920.1 
AF026925.1 AF026932.1 AF032351.1 AF047202.1 AF047216.1 AF047217.1 AF047229.1 AF047230.1 
AF047231.1 AF047233.1 AF047234.1 AF047239.1 AF052765.1 AF052772.1 AF052797.1 AF052801.1 
AF052802.1 AF052804.1 AF052806.1 AF052809.1 AF052819.1 AF052820.1 AF052821.1 AF052822.1 
AF052825.1 AF052826.1 AF054643.1 AF054644.1 AF054646.1 AF058057.1 AF058063.1 AF058068.1 
AF058072.1 AF058075.1 AF058078.1 AF060120.1 AF060121.1 AF060123.1 AF060125.1 AF060130.1 
AF060131.1 AF060134.1 AF060135.1 AF060136.1 AF060138.1 AF060140.1 AF060145.1 AF060147.1 
AF063694.1 AF063695.1 AF063703.1 AF063704.1 AF063705.1 AF063706.1 AF063707.1 AF063709.1 
AF063715.1 AF063716.1 AF063720.1 AF063721.1 AF063723.1 AF063726.1 AF063727.1 AF063730.1 
AF063731.1 AF063735.1 AF063736.1 AF063737.1 AF063738.1 AF063739.1 AF063740.1 AF063741.1 
AF063742.1 AF063745.1 AF063748.1 AF063754.1 AF063755.1 AF063756.1 AF063757.1 AF063759.1 
AF063765.1 AF063771.1 AF063772.1 AF063773.1 AF063774.1 AF063775.1 AF063778.1 AF063780.1 
AF064498.1 AF064500.1 AF064502.1 AF064503.1 AF064505.1 AF064506.1 AF064507.1 AF064513.1 
AF076200.1 AF076201.1 AF099192.1 AF103591.1 AF103594.1 AF103595.1 AF103598.1 AF103601.1 
AF103605.1 AF103610.1 AF103611.1 AF103612.1 AF103614.1 AF103618.1 AF103620.1 AF103622.1 
AF103623.1 AF103628.1 AF103629.1 AF103630.1 AF103636.1 AF103637.1 AF103638.1 AF103639.1 
AF103640.1 AF103641.1 AF103643.1 AF103646.1 AF103649.1 AF103653.1 AF103654.2 AF103657.1 
AF103661.1 AF103662.1 AF103667.1 AF103668.1 AF103669.1 AF103673.1 AF103674.1 AF103681.1 
AF103683.1 AF103689.1 AF103692.1 AF103694.1 AF103700.1 AF103704.1 AF103709.1 AF103710.1 
AF103713.1 AF103718.1 AF103719.1 AF103720.1 AF103723.1 AF115352.1 AF115355.1 AF124170.1 
AF124172.1 AF124176.1 AF124178.1 AF124186.1 AF194542.1 AF194543.1 AF194544.1 AF194547.1 
AF194548.1 AF194550.1 AF194552.1 AF194554.1 AF194555.1 AF194556.1 AF194557.1 AF194558.1 
AF194559.1 AF194560.1 AF194561.1 AF194562.1 AF194563.1 AF194564.1 AF194565.1 AF194566.1 
AF194567.1 AF194568.1 AF194570.1 AF194571.1 AF194572.1 AF194573.1 AF194574.1 AF194575.1 
AF194576.1 AF194577.1 AF194578.1 AF194579.1 AF194580.1 AF194581.1 AF194585.1 AF194586.1 
AF194587.1 AF194588.1 AF194589.1 AF194590.1 AF194592.1 AF194593.1 AF194595.1 AF194598.1 
AF194599.1 AF194600.1 AF194601.1 AF194602.1 AF194603.1 AF194604.1 AF194605.1 AF194607.1 
AF194608.1 AF194609.1 AF194613.1 AF194614.1 AF194615.1 AF194616.1 AF194617.1 AF194618.1 
AF194619.1 AF194620.1 AF194621.1 AF194622.1 AF194623.1 AF194624.1 AF194625.1 AF194626.1 
AF194627.1 AF194628.1 AF194629.1 AF194630.1 AF194631.1 AF194632.1 AF194633.1 AF194634.1 
AF194635.1 AF194636.1 AF194637.1 AF194638.1 AF194639.1 AF194640.1 AF194641.1 AF194643.1 
AF194644.1 AF194645.1 AF194646.1 AF194648.1 AF194649.1 AF194651.1 AF194655.1 AF194657.1 
AF194658.1 AF194659.1 AF194660.1 AF194661.1 AF194662.1 AF194663.1 AF194664.1 AF194665.1 
AF194666.1 AF194667.1 AF194668.1 AF194669.1 AF194670.1 AF194671.1 AF194672.1 AF194673.1 
AF194674.1 AF194675.1 AF194676.1 AF194677.1 AF194678.1 AF194679.1 AF194680.1 AF194681.1 
AF194682.1 AF194683.1 AF194684.1 AF194685.1 AF194686.1 AF194687.1 AF194688.1 AF194689.1 
AF194690.1 AF194691.1 AF194692.1 AF194693.1 AF194694.1 AF194695.1 AF194696.1 AF194697.1 
AF194698.1 AF194699.1 AF194700.1 AF194701.1 AF194702.1 AF194703.1 AF194704.1 AF194705.1 
AF194706.1 AF194707.1 AF194708.1 AF194709.1 AF194710.1 AF194711.1 AF194712.1 AF194713.1 
AF194714.1 AF194787.1 AF194788.1 AF194789.1 AF194790.1 AF194791.1 AF194792.1 AF194793.1 
AF194794.1 AF194795.1 AF194796.1 AF194797.1 AF194798.1 AF194799.1 AF194800.1 AF194801.1 
AF194802.1 AF194803.1 AF194804.1 AF194805.1 AF194806.1 AF194807.1 AF194808.1 AF194809.1 
AF194810.1 AF194811.1 AF194812.1 AF194813.1 AF194814.1 AF194815.1 AF194816.1 AF233255.1 
AF320832.1 AF320843.1 AF417851.1 AF417852.1 AF462648.1 AF462664.1 AF462679.1 AF462680.1 
AF462688.1 AJ006162.1 AJ007955.1 AJ132425.1 AJ132855.1 AJ132856.1 AJ224900.1 AJ233717.1 
AJ233724.1 AJ233727.1 AJ233728.1 AJ233734.1 AJ233735.1 AJ241391.1 AJ241394.1 AJ241403.1 
AJ241405.1 AJ249377.1 AJ249792.1 AJ278777.1 AJ298039.1 AJ298040.1 AJ298043.1 AJ298049.1 
AJ298050.1 AJ298051.1 AJ298614.1 AJ298615.1 AJ298619.1 AJ308452.1 AJ308454.1 AJ308455.1 
AJ308456.1 AJ308457.1 AJ308461.1 AJ309319.1 AJ319669.1 AJ319671.1 AJ388658.1 AJ388659.1 
AJ388660.1 AJ388665.1 AJ388666.1 AJ399847.1 AJ399863.1 AJ408274.1 AJ408283.1 AJ408287.1 
AJ408290.1 AJ430754.1 AJ430763.1 AJ430764.1 AJ430768.1 AJ430773.1 AJ496492.1 AJ496497.1 
AJ496501.1 AJ496502.1 AJ697911.1 AJ697912.1 AJ697913.1 AJ698337.1 AJ698338.1 AK057174.1 
AK097035.1 AK097040.1 AK098158.1 AK125585.1 AK125629.1 AK127411.1 AK129585.1 AK129603.1 
AK130446.1 AK130461.1 AK130519.1 AL713800.1 AM181303.1 AM181363.1 AM181364.1 AM181367.1 
AM181373.1 AM181375.1 AM181376.1 AM181378.1 AM184001.1 AM184002.1 AM184003.1 AM184004.1 
AM184005.1 AM184012.1 AM184013.1 AM184014.1 AM184015.1 AM184016.1 AM184017.1 AM184018.1 
AM184019.1 AM184068.1 AM184069.1 AM184071.1 AY043088.1 AY043090.1 AY043110.1 AY043115.1 
AY043118.1 AY043122.1 AY043153.1 AY043159.1 AY062356.1 AY062358.1 AY062360.1 AY172960.1 
AY172962.1 AY180389.1 AY190819.1 AY190821.1 AY190825.1 AY190827.1 AY190829.1 AY193807.1 
AY204760.1 AY204762.1 AY206993.1 AY515013.1 AY574936.1 AY574941.1 AY574946.1 AY683199.1 
AY683200.1 AY683201.1 AY685288.1 AY685290.1 AY685291.1 AY685292.1 AY685293.1 AY685294.1 
AY685362.1 AY685363.1 AY685364.1 AY685365.1 AY685366.1 AY685367.1 AY685368.1 AY685369.1 
AY685370.1 AY685372.1 AY685375.1 AY685377.1 AY685381.1 AY685382.1 AY685384.1 AY685385.1 
AY685386.1 AY685387.1 AY686895.1 AY686896.1 AY941990.1 AY941992.1 AY942000.1 AY942005.1 
AY942021.1 AY942032.1 AY942033.1 AY942037.1 AY942071.1 AY942077.1 AY942083.1 AY942087.1 
AY942102.1 AY942109.1 AY942125.1 AY950794.1 AY955078.1 AY955080.1 AY998674.1 BC007782.2 
BC012159.1 BC015833.1 BC018749.1 BC020233.1 BC020236.1 BC022098.1 BC022822.1 BC022823.1 
BC028090.1 BC030983.1 BC030984.1 BC032452.1 BC033102.1 BC054883.1 BC054893.1 BC062711.1 
BC064491.1 BC071725.1 BC071804.1 BC072392.1 BC073762.1 BC073769.1 BC073770.1 BC073787.1 
BC073794.1 BC089413.1 BC089414.1 BC089418.1 BC093098.1 BC107852.1 D01059.1 D84141.1 
DQ109967.1 DQ187535.1 DQ187536.1 DQ187537.1 DQ187540.1 DQ187622.1 DQ187723.1 DQ187724.1 
DQ205170.1 DQ205172.1 DQ205174.1 DQ234400.1 DQ322733.1 DQ322734.1 DQ322762.1 DQ322763.1 
DQ322771.1 DQ322773.1 DQ322787.1 DQ322816.1 DQ322938.1 DQ322939.1 DQ322940.1 DQ322941.1 
DQ322979.1 DQ323004.1 DQ490733.1 EF589387.1 EF589389.1 EF589391.1 EF589397.1 EF589400.1 
EF589406.1 EF589407.1 EF589410.1 EF589412.1 EF589413.1 EF589416.1 EF589423.1 EF589424.1 
EF589428.1 EF589429.1 EF589430.1 EF589444.1 EF589445.1 EF589453.1 EF589454.1 EF589461.1 
EF589466.1 EF589467.1 EF589473.1 EF589479.1 EF589489.1 EF589500.1 EF589504.1 EF589506.1 
EF589510.1 EF589521.1 EF589530.1 EF589533.1 EF589541.1 EF589542.1 EF589549.1 EF589556.1 
EF589557.1 EF589560.1 EF589562.1 EF589566.1 EF710783.1 EF710784.1 EF710853.1 EF710854.1 
EF710855.1 EF710856.1 EF710857.1 EF710858.1 EF710908.1 EF710909.1 EF710910.1 EF710936.1 
EF710937.1 EF710938.1 EF710939.1 EF710940.1 EF710941.1 EF710942.1 EF710943.1 EF710944.1 
EF710945.1 EF710994.1 EF710995.1 EF710996.1 EF710997.1 EF710998.1 EF711016.1 EF711017.1 
EF711018.1 EF711019.1 EF711020.1 EF711021.1 EF711022.1 EF711023.1 EU169677.2 EU599320.1 
EU599321.1 EU599322.1 EU599330.1 EU599335.1 EU599339.1 EU599348.1 EU599349.1 EU599350.1 
EU599354.1 EU599356.1 EU599359.1 EU599360.1 EU825948.1 EU937523.1 FJ039804.1 FJ039805.1 
FJ200244.1 FJ385438.1 FJ385442.1 FJ385443.1 FJ385449.1 FJ385456.1 FJ385462.1 FJ385474.1 
FJ385505.1 FJ385507.1 FJ385525.1 FJ385528.1 FJ385551.1 FJ385552.1 FJ385555.1 FJ385558.1 
FJ429651.1 HM995992.1 HM996015.1 HM996058.1 HM996111.1 HM996172.1 HM996203.1 HM996209.1 
HM996218.1 HM996488.1 HM996513.1 HQ129865.1 HQ129867.1 HQ172111.1 HQ172115.1 HQ172120.1 
HQ172123.1 HQ172126.1 HQ172130.1 HQ172133.1 HQ172141.1 HQ172143.1 HQ172144.1 HQ172149.1 
HQ172151.1 HQ890344.1 HQ890351.1 HQ890354.1 HQ890360.1 JF740067.1 JF740071.1 JF740072.1 
JF791169.1 JF806289.1 JN130389.1 JN201911.1 JQ301913.1 JQ301919.1 L01277.1 L03628.1 
L03629.1 L03631.1 L03632.1 L03633.1 L03680.1 L03682.1 L21956.1 L21959.1 
L25296.1 L26400.1 L26532.1 L26534.1 L26902.1 L29158.1 L29159.1 L29160.1 
L29161.1 L29164.1 L33026.1 L38436.1 L38563.1 L38565.1 L39129.1 L43084.1 
L43088.1 M12025.1 M18645.1 M75139.1 M75282.1 M87790.1 M97924.1 S42404.1 
S56194.1 S62232.1 S66100.1 S67986.1 S73129.1 S73510.1 S77601.1 S80751.1 
S80758.1 U07991.1 U09085.1 U09893.1 U09898.1 U09899.1 U09900.1 U31964.1 
U36537.1 U36538.1 U36540.1 U36541.1 U38335.1 U38336.1 U38338.1 U38339.1 
U38341.1 U38342.1 U38343.1 U38344.1 U38345.1 U38346.1 U38589.1 U38662.1 
U43772.1 U63213.1 U70234.1 U70239.1 U76675.1 U76678.1 U76680.1 U76684.1 
U86669.1 U86805.1 U95247.1 U95248.1 U96393.1 U97248.1 X14583.1 X52112.1 
X57801.1 X57803.1 X57804.1 X57806.1 X57809.1 X57810.1 X57811.1 X57812.1 
X57813.1 X57814.1 X57815.1 X57816.1 X57817.1 X57818.1 X57821.1 X57822.1 
X57824.1 X62125.1 X64132.1 X64169.1 X72746.1 X72747.1 X83712.1 X87892.1 
X91131.1 X91805.1 X95739.1 X98897.1 Y08198.1 Y12721.1 Y14738.1 Y15770.1 
Y16714.1 Y17143.1 Y17940.1 Y17956.1 Y18121.1 Z18332.1 Z18333.1 Z18823.1 
Z18844.1 Z19546.1 Z46313.1 Z46346.1 Z46623.1 Z46848.1 Z46858.1 Z74694.1 
Z75558.1 

24/287 DOTS entries (see all 287):

DT.100885122  DT.95222178  DT.40267692  DT.91720675  DT.95068785  DT.91962204  DT.100885135  DT.91934757 
DT.91939027  DT.100885115  DT.91769116  DT.100046818  DT.120678012  DT.87079052  DT.91683758  DT.87018169 
DT.100046628  DT.92049444  DT.120676905  DT.40231338  DT.120676930  DT.87003223  DT.92006280  DT.100885154 

3 AceView cDNA sequences:

S73129 AF064505 AF058077 

GeneLoc Exon Structure


Expression
for IGLV3-25 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IGLV3-25 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image
See IGLV3-25 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IGLV3-25

SOURCE GeneReport for Unigene cluster: Hs.449585
    SABiosciences Custom PCR Arrays for IGLV3-25
Primer
Products:		Browse OriGene genome-wide validated SYBR primer pairs
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In Situ
Assay Products: 
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Orthologs
for IGLV3-25 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for IGLV3-25 gene from 1/3 species (see all 3)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
lizard
(Anolis carolinensis)		 Reptilia --
--
 --
 47(a)
28(a)
 many ↔ many
many ↔ many
 GL343282.1(569146-570830)
GL343282.1(588802-599691)


ENSEMBL Gene Tree for IGLV3-25 (if available)
TreeFam Gene Tree for IGLV3-25 (if available) 

Paralogs
for IGLV3-25 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for IGLV3-25 gene
IGLV3-122  IGLV2-182  IGLV3-192  IGLV1-512  IGLV9-492  IGLV3-222  IGLV2-232  IGLV8-612  
IGLV4-602  IGLV1-472  IGLV2-142  IGLV2-332  IGLV3-322  IGLV5-522  IGLV1-442  IGLV3-212  
IGLV2-112  IGLV3-102  IGLV3-92  IGLV5-372  IGLV1-502  VPREB32  IGLV2-82  IGLV10-542  
IGLV7-432  IGLV5-452  IGLV3-272  IGLV7-462  IGLV11-552  IGLV1-402  IGLV5-482  IGLV3-12  
IGLV4-32  VPREB12  IGLV6-572  IGLV3-162  IGLV4-692  IGLV1-362  
18/78 SIMAP similar genes for IGLV3-25 using alignment to 1 protein entry:     Q5NV90_HUMAN(see all similar genes):
V2-7    IGLV3-27    VL87-2    IGLV3-16    V2-1    VL3L
V2-13    IGLV3-19    IGLV3-22    IgLC-rG    V2-14    V2-6
V3    IGL@    VL4    IGLV3-12    V1-17    V1-2

IGLV3-25 for paralogs           About GeneDecksing



Genomic Variants
for IGLV3-25 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGLV3-25
DNA2.0 Custom Variant and Variant Library Synthesis for IGLV3-25

Disorders / Diseases
for IGLV3-25 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Publications
for IGLV3-25 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for IGLV3-25 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IGLV3-25)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  2. Recognition of immunoglobulins by Fcgamma receptors. (PubMed id 11955599)1 Radaev S. and Sun P. (2002)
  3. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PubMed id 9074928)1 Kawasaki K....Shimizu N. (1997)
  4. Sequence and evolution of the human germline V lambda repertoire. (PubMed id 8951372)1 Williams S.C....Winter G. (1996)
  5. Activation of C1r by proteolytic cleavage. (PubMed id 1249422)1 Ziccardi R.J. and Cooper N.R. (1976)
  6. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PubMed id 814163)1 Ziccardi R.J. and Cooper N.R. (1976)

External Searches for IGLV3-25 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing IGLV3-25 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 28793 HGNC: 5908 AceView: IGLV3-25 Ensembl:ENSG00000211659 euGenes: HUgn28793
ECgene: IGLV3-25 H-InvDB: IGLV3-25

Other Databases showing IGLV3-25 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing IGLV3-25 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for IGLV3-25 Pharmacogenomics, SNPs, Pathways
IMGT entry for IGLV3-25 The international ImMunoGeneTics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.

Intellectual Property
for IGLV3-25 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for IGLV3-25 gene:
Search GeneIP for patents involving IGLV3-25

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for IGLV3-25 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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Advanced Cell Diagnostics
About This Section

 
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