IGLV3-10 Gene protein-coding GIFtS : 20 GCID: GC22 P023154
Immunoglobulin Lambda Variable 3-10
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Aliasesfor IGLV3-10 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Aliases Immunoglobulin Lambda Variable 3-10 1 2 IGLV3102 V2-72
Export aliases for IGLV3-10 gene to outside databases Previous GC identifers: GC22U990155 GC22P021479
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Summariesfor IGLV3-10 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus GeneCards Summary for IGLV3-10 Gene: IGLV3-10 (immunoglobulin lambda variable 3-10) is a protein-coding gene. An important paralog of this gene is IGLV2-18 .
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Genomic Viewsfor IGLV3-10 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus Regulatory elements: Search for regulatory transcription factor binding sites for IGLV3-10 Other transcription factors Search Chromatin IP Primers for IGLV3-10 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q11.2 Ensembl cytogenetic band: 22q11.22 HGNC cytogenetic band: 22q11.2 IGLV3-10 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22P023154: view genomic region
(about GC identifiers )
Start: 23,154,244 bp from pter End:
23,154,782 bp from pter
Size: 539 bases Orientation:
plus strand
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Proteinsfor IGLV3-10 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section GeneCards Plus UniProtKB/TrEMBL: A2MYD4 See
protein sequence )Recommended Name: Size : 96 amino acids; 10352 DaExplore proteomics data for IGLV3-10 at MOPED See IGLV3-10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB
ENSEMBL proteins: ENSP00000374850 IGLV3-10 Human Recombinant
Protein Products: IGLV3-10 Antibody
Products: IGLV3-10 Assay Products:
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Domains /for IGLV3-10 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: IGL: Immunoglobulins / IGL locus 4 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry A2MYD4 ProtoNet protein and cluster: A2MYD4
About GeneDecksing
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Functionfor IGLV3-10 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Gene Ontology (GO): 1 molecular function term : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
-- --
About GeneDecksing Animal Models: Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
Cell Line GenScript Custom overexpressing Cell Line Services for IGLV3-10 Browse ESI BIO Cell Lines and PureStem Progenitors for IGLV3-10 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLV3-10
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Localizationfor IGLV3-10 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Subcellular locations from COMPARTMENTS : Compartment Confidence extracellular 3
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Pathways & Interactionsfor IGLV3-10 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IGLV3-10 Interactions: Search GeneGlobe Interaction Network for IGLV3-10
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Drugs & Compoundsfor IGLV3-10 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus Browse compounds at ApexBio Browse Tocris compounds for IGLV3-10
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Transcriptsfor IGLV3-10 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene , and/or
QIAGEN
)About This Section GeneCards Plus 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390315 Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
Selected AceView cDNA sequences (see all 97 ):
AF194648 AF194698 CR592011 CR623617 AF194645 L35920 CR623132 AF194669 AF064507 L25296 CR605950 AF194679 CR593480 AF063703 AY573191 AF194643 AF058069 AF194714 AJ318021 CR617925 BC033102 AF194651 AJ318022 AB064037 GeneLoc Exon Structure
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Expression for IGLV3-10 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus IGLV3-10 expression in normal human tissues
(normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
IGLV3-10 Protein expression data from MOPED1 2 3 : About this image Custom PCR Arrays for IGLV3-10 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat IGLV3-10 QuantiTect SYBR Green Assays in human mouse rat QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLV3-10
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Orthologsfor IGLV3-10 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus Orthologs for IGLV3-10 gene from Selected species (see all 4 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
dog Mammalia --
Uncharacterized protein
42(a)
1 → many
26(27303190-27304407)
lizard Reptilia --
Uncharacterized protein
48(a)
1 → many
GL343282.1(569146-570830)
ENSEMBL Gene Tree for IGLV3-10 (if available)TreeFam Gene Tree for IGLV3-10 (if available)
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Paralogsfor IGLV3-10 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus Paralogs for IGLV3-10 gene IGLV2-18 2 IGLV3-9 2 IGLV3-12 2 IGLV3-19 2 IGLV1-50 2 IGLV3-25 2 IGLV2-8 2 IGLV1-51 2 IGLV10-54 2 IGLV3-22 2 IGLV2-23 2 IGLV7-43 2 IGLV8-61 2 IGLV7-46 2 IGLV3-27 2 IGLV1-47 2 IGLV2-14 2 IGLV1-40 2 IGLV3-1 2 IGLV2-33 2 IGLV3-32 2 IGLV6-57 2 IGLV1-44 2 IGLV3-21 2 IGLV2-11 2 IGLV3-16 2 IGLV1-36 2 About GeneDecksing 2 Pseudogenes.org Pseudogenes for IGLV3-10 PGOHUM00000246496 PGOHUM00000246512
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Genomic Variantsfor IGLV3-10 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Site Specific Mutation Identification with PCR Assays
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Disorders
/ Diseasesfor IGLV3-10 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus
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Publicationsfor IGLV3-10 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed articles for IGLV3-10 gene integrated from 10 sources :(articles sorted by number of sources associating them with IGLV3-10) Utopia : connect your pdf to the dynamic
One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PubMed id 9074928) 1 (Genome Res. 1997) Sequence and evolution of the human germline V lambda repertoire. (PubMed id 8951372) 1 (J. Mol. Biol. 1996)
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External Searches for IGLV3-10 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing IGLV3-10 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing IGLV3-10 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing IGLV3-10 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
Name Description PharmGKB entry for IGLV3-10 Pharmacogenomics, SNPs, Pathways IMGT entry for IGLV3-10The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section GeneCards Plus Patent Information for IGLV3-10 gene: IGLV3-10 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IGLV3-10 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , and ESI BIO , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat IGLV3-10 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing IGLV3-10 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat Predesigned siRNA for gene silencing in human mouse rat QuantiFast Probe-based Assays in human mouse rat QuantiTect SYBR Green Assays in human mouse rat Custom PCR Arrays for IGLV3-10 Search Chromatin IP Primers for IGLV3-10 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat IGLV3-10 Search GeneGlobe Interaction Network for IGLV3-10 Search Regulatory tfbs for IGLV3-10
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLV3-10
Search ThermoFisher Antibodies for IGLV3-10
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLV3-10
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Proteins for IGLV3-10
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