IGLV1-44 Gene
protein-coding GIFtS : 30
GCID: GC22 P022734
immunoglobulin lambda variable 1-44
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Aliasesfor IGLV1-44 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Immunoglobulin Lambda Variable 1-44 1 2 V1-162 4 IGLV1442
Export aliases for IGLV1-44 gene to outside databases Previous GC identifers: GC22U990175 GC22P021059 GC22P021065 GC22P005692
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Summariesfor IGLV1-44 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor IGLV1-44 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000022.10 NC_018933.1 NT_011520.12 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for IGLV1-44 Other transcription factors Search SABiosciences Chromatin IP Primers for IGLV1-44 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLV1-44
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q11.2 Ensembl cytogenetic band: 22q11.22 HGNC cytogenetic band: 22q11.2 IGLV1-44 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22P022734: view genomic region
(about GC identifiers )
Start:
22,734,288 bp from pter
End:
22,735,716 bp from pter
Size:
1,429 bases
Orientation:
plus strand
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Proteinsfor IGLV1-44 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/TrEMBL: Q5NV81 (See
protein sequence )Recommended Name: V1-16 protein Size : 99 amino acids; 10284 DaIGLV1-44 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374832 Reactome Protein details: Q5NV81 Human Recombinant Protein Products for IGLV1-44: IGLV1-44 Antibody Products: Assay Products for IGLV1-44:
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Protein
Domains / Familiesfor IGLV1-44 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
IGLV1-44 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q5NV81 ProtoNet protein and cluster: Q5NV81
1 Blocks protein family : IPB003596 Immunoglobulin V-type
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Functionfor IGLV1-44 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models:
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Pathways & Interactionsfor IGLV1-44 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 Cleavage of Alpha-1-Microglobulin 2 Immune System 3 Regulation of actin dynamics for phagocytic cup formation
Pathway sources See GeneCards unified pathways Show all pathways 5/17
Reactome Pathways for IGLV1-44 (see all 17 )
IGLV1-44 for pathways About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGLV1-44 STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for IGLV1-44 (ENSP00000374832 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor IGLV1-44 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for IGLV1-44 Search CenterWatch for drugs/clinical trials and news about IGLV1-44
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Transcriptsfor IGLV1-44 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for IGLV1-44:
Immunoglobulin lambda variable 1-44 Hs.655198 [show with all ESTs ] Unigene Representative Sequence: BQ708343 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390297 Additional cDNA sequence: AB063980.1 AB063981.1 AB063982.1 AB064003.1 AB064007.1 AB064038.1 AB064039.1 AB064040.1 AF001790.1 AF063767.1 AF063777.1 AF103604.1 AF103619.1 AF103691.1 AF103721.1 AF396471.1 AF396473.1 AF396475.1 AF396477.1 AF396479.1 AF533987.1 AJ001170.1 AJ241360.1 AJ408273.1 AJ408278.1 AJ430770.1 AJ430772.1 AM184067.1 AY043091.1 AY099260.1 AY193809.1 AY193811.1 AY193813.1 AY193815.1 AY193817.1 AY193819.1 AY206991.1 AY577301.1 AY685379.1 AY685380.1 AY686916.1 AY686929.1 AY847517.1 AY942030.1 AY950796.1 AY950798.1 AY957533.1 DQ187504.1 DQ187523.1 DQ187610.1 DQ187635.1 DQ205148.1 DQ322743.1 DQ322761.1 DQ322772.1 DQ322815.1 DQ322903.1 DQ322953.1 EF589436.1 EF589440.1 EF589531.1 FJ385510.1 HM996235.1 HM996274.1 HM996539.1 HQ890346.1 HQ890352.1 JF740069.1 JF806462.1 JX213638.1 L26896.1 M28137.1 U86802.1 U96394.1 X54438.1 X54446.1 X98752.1 Y09389.1 Z46312.1 Z46625.1 Z74670.1
24/41 DOTS entries (see all 41 ): DT.100885149 DT.120676987 DT.120676837 DT.120677017 DT.319469 DT.100032366 DT.100046825 DT.420912
DT.91769054 DT.91728360 DT.95090606 DT.95183816 DT.95298046 DT.100046157 DT.95303883 DT.120677826 DT.87002873 DT.91660956 DT.91927893 DT.97867854 DT.95215487 DT.120676886 DT.91832774 DT.97868390 2 AceView cDNA sequences :
U09907 M88312 GeneLoc Exon Structure
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Expression for IGLV1-44 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IGLV1-44 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image See IGLV1-44 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IGLV1-44 SOURCE GeneReport for Unigene cluster: Hs.655198 SABiosciences Custom PCR Arrays for IGLV1-44
Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat IGLV1-44 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLV1-44 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLV1-44
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Orthologsfor IGLV1-44 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for IGLV1-44 gene from 1/2 species (see all 2 ) About this table
ENSEMBL Gene Tree for IGLV1-44 (if available)TreeFam Gene Tree for IGLV1-44 (if available)
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Paralogsfor IGLV1-44 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IGLV1-44 gene IGLV3-12 2 IGLV2-18 2 IGLV3-19 2 IGLV1-51 2 IGLV9-49 2 IGLV3-22 2 IGLV2-23 2 IGLV8-61 2 IGLV4-60 2 IGLV1-47 2 IGLV2-14 2 IGLV2-33 2 IGLV3-32 2 IGLV5-52 2 IGLV3-21 2 IGLV2-11 2 IGLV3-10 2 IGLV3-9 2 IGLV5-37 2 IGLV1-50 2 VPREB3 2 IGLV3-25 2 IGLV2-8 2 IGLV10-54 2 IGLV7-43 2 IGLV5-45 2 IGLV3-27 2 IGLV7-46 2 IGLV1-40 2 IGLV11-55 2 IGLV5-48 2 IGLV3-1 2 IGLV4-3 2 VPREB1 2 IGLV6-57 2 IGLV3-16 2 IGLV4-69 2 IGLV1-36 2 18/95 SIMAP similar genes for IGLV1-44 using alignment to 1 protein entry: Q5NV81_HUMAN (see all similar genes ):V1-17 V1-18 V1-19 IGLV1-40 IGLV1-36 V1-11 IGLV2-18 HuC4lambda Vlambda IGLV2-11 V1-2 V1-4 VL1 IGL@ IGLV2-23 V3 V1-22 V2-1 V2-14
IGLV1-44 for paralogs About GeneDecksing
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Genomic Variantsfor IGLV1-44 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor IGLV1-44 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
IGLV1-44 for disorders About GeneDecksing 3 diseases for IGLV1-44 : About MalaCards papilledema poems syndrome hypertrichosis 3 diseases from the University of Copenhagen DISEASES database for IGLV1-44 :Papilledema Hypertrichosis POEMS syndrome Export disorders for IGLV1-44 gene to outside databases
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Publicationsfor IGLV1-44 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for IGLV1-44 gene integrated from 9 sources : (articles sorted by number of sources associating them with IGLV1-44) Utopia : connect your pdf to the dynamic world of online information
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) Recognition of immunoglobulins by Fcgamma receptors. (PubMed id 11955599) 1 Radaev S. and Sun P. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Molecular analysis of polyreactive monoclonal antibodies from rheumatic carditis: human anti-N-acetylglucosamine/anti-myosin antibody V region genes. (PubMed id 9712075) 1 Adderson E.E.... Cunningham M.W. (1998) One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PubMed id 9074928) 1 Kawasaki K....Shimizu N. (1997) Sequence and evolution of the human germline V lambda repertoire. (PubMed id 8951372) 1 Williams S.C....Winter G. (1996) Activation of C1r by proteolytic cleavage. (PubMed id 1249422) 1 Ziccardi R.J. and Cooper N.R. (1976) Physicochemical and functional characterization of the C1r subunit of the first complement component. (PubMed id 814163) 1 Ziccardi R.J. and Cooper N.R. (1976)
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External Searches for IGLV1-44 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing IGLV1-44 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing IGLV1-44 gene
(According to HUGE )
About This Section --
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Specialized Databases showing IGLV1-44 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for IGLV1-44 Pharmacogenomics, SNPs, Pathways IMGT entry for IGLV1-44 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for IGLV1-44 gene: Search GeneIP for patents involving IGLV1-44 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IGLV1-44 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGLV1-44 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGLV1-44 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLV1-44 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLV1-44 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLV1-44 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLV1-44
Search ThermoFisher Antibodies for IGLV1-44
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLV1-44
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Search Box for IGLV1-44
Summaries for IGLV1-44
Transcripts for IGLV1-44
Variants for IGLV1-44
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