Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



IGLL5 Gene

protein-coding   GIFtS: 31
GCID: GC22P023317

Immunoglobulin Lambda-Like Polypeptide 5

  See IGLL5-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Immunoglobulin Lambda-Like Polypeptide 51 2
Germline Immunoglobulin Lambda 12 3
G Lambda-12 3
Immunoglobulin Lambda-3 Surrogate Light Chain2
Omega Light Chain Protein 14.12

External Ids:    HGNC: 384761   Entrez Gene: 1004230622   Ensembl: ENSG000002547097   UniProtKB: B9A0643   

Export aliases for IGLL5 gene to outside databases

Previous GC identifers: GC22U900705 GC22P006197 GC22P023231 GC22P023233 GC22P023239 GC22P023299


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for IGLL5 Gene:
This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin
lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is
unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1
and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript
variants. (provided by RefSeq, May 2010)

GeneCards Summary for IGLL5 Gene:
IGLL5 (immunoglobulin lambda-like polypeptide 5) is a protein-coding gene. Diseases associated with IGLL5 include carotid artery dissection. An important paralog of this gene is IGKC.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Search for regulatory transcription factor binding sites for IGLL5
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for IGLL5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IGLL5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.22   Ensembl cytogenetic band:  22q11.22   HGNC cytogenetic band: 22q11.22

IGLL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGLL5 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P023317:  view genomic region     (about GC identifiers)

Start:
23,229,960 bp from pter      End:
23,238,287 bp from pter
Size:
8,328 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: IGLL5_HUMAN, B9A064 (See protein sequence)
Recommended Name: Immunoglobulin lambda-like polypeptide 5 precursor  
Size: 214 amino acids; 23063 Da
Miscellaneous: Located within the immunoglobulin lambda locus, but does not require somatic rearrangement for
expression
Alternative splicing: 2 isoforms:  B9A064-1   B9A064-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IGLL5: NX_B9A064

Explore proteomics data for IGLL5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IGLL5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001171597.1  NP_001243225.1  

    ENSEMBL proteins: 
     ENSP00000431254   ENSP00000436353   ENSP00000434368  

    IGLL5 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for IGLL5
    OriGene Custom MassSpec
    OriGene Custom Protein Services for IGLL5
    GenScript Custom Purified and Recombinant Proteins Services for IGLL5
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for IGLL5 

    IGLL5 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for IGLL5
    Novus Biologicals IGLL5 Antibody
    Search for Antibodies for IGLL5 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for IGLL5
    LSBio Antibodies in human, mouse, rat for IGLL5

    IGLL5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for IGLL5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for IGLL5
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for IGLL5 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    C1SET: Immunoglobulin superfamily / C1-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR003597 Ig_C1-set
     IPR007110 Ig-like_dom
     IPR003006 Ig/MHC_CS

    Graphical View of Domain Structure for InterPro Entry B9A064

    ProtoNet protein and cluster: B9A064

    UniProtKB/Swiss-Prot: IGLL5_HUMAN, B9A064
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain


    Find genes that share domains with IGLL5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding ----
    GO:0005515protein binding ----
         
    Find genes that share ontologies with IGLL5           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IGLL5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IGLL5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IGLL5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IGLL5

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat IGLL5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate IGLL5
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse OriGene RNAi
    Predesigned siRNA for gene silencing in human, mouse, rat IGLL5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IGLL5

    Clone
    Products:
         
    OriGene clones in human, mouse for IGLL5 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IGLL5 (NM_001178126)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLL5
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLL5

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for IGLL5
    Browse ESI BIO Cell Lines and PureStem Progenitors for IGLL5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLL5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    IGLL5_HUMAN, B9A064: Secreted (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    nucleus2
    plasma membrane2
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane ----

    Find genes that share ontologies with IGLL5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IGLL5
    Interactions:

        Search GeneGlobe Interaction Network for IGLL5

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response ----
    GO:0006956complement activation ----
    GO:0006958complement activation, classical pathway ----
    GO:0038095Fc-epsilon receptor signaling pathway ----
    GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis ----

    Find genes that share ontologies with IGLL5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IGLL5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for IGLL5 gene (2 alternative transcripts): 
    NM_001178126.1  NM_001256296.1  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000526893(uc011aiw.2 uc010gtu.2) ENST00000532223(uc021wmq.1)
    ENST00000531372
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IGLL5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate IGLL5
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse OriGene RNAi
    Predesigned siRNA for gene silencing in human, mouse, rat IGLL5
    Clone
    Products:
         
    OriGene clones in human, mouse for IGLL5 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IGLL5 (NM_001178126)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLL5
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLL5
    Primer
    Products:
        
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IGLL5
      QuantiTect SYBR Green Assays in human, mouse, rat IGLL5
      QuantiFast Probe-based Assays in human, mouse, rat IGLL5

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    IGLL5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IGLL5 Expression
    About this image

    IGLL5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IGLL5 Protein Expression

    UniProtKB/Swiss-Prot: IGLL5_HUMAN, B9A064
    Tissue specificity: Contrary to IGLL1, not expressed in pre-B-cells

        Custom PCR Arrays for IGLL5
    Primer
    Products:
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IGLL5
    QuantiTect SYBR Green Assays in human, mouse, rat IGLL5
    QuantiFast Probe-based Assays in human, mouse, rat IGLL5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLL5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for IGLL5 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Igll11 immunoglobulin lambda-like polypeptide 1 72.17(n)
    60.5(a)
      16136  NM_001190325.1  NP_001177254.1 
    chicken
    (Gallus gallus)
    Aves --
    Ig lambda chain V-1 region
    35(a)
    1 → many
    15(7928727-7933299)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    55(a)
    31(a)
    many ↔ many
    many ↔ many
    AAWZ02041299(1275-1595)
    GL343282.1(588802-599691)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1017350331 immunoglobulin lambda-like polypeptide 1-like 54.93(n)
    47.2(a)
      101735033  XM_004911370.1  XP_004911427.1 
    zebrafish
    (Danio rerio)
    Actinopterygii FP016018.16
    Uncharacterized protein
    12(a)
    many ↔ many
    3(59520880-59521182) ENSDARG00000093689


    ENSEMBL Gene Tree for IGLL5 (if available)
    TreeFam Gene Tree for IGLL5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for IGLL5 gene
    IGLL11 2  IGKC2  IGLC12  IGLC32  IGLC72  IGLC22  
    15 SIMAP similar genes for IGLL5 using alignment to 1 protein entry:     IGLL5_HUMAN:
    C1 segment    DKFZp781M0386    IGLC1    IGLC7    DKFZp667J0810    IGLC2
    IGLC3    IGLC6    IGLL1    IGL@    IgLC-rG    IGKC
    HLA-DRB1    HLA-DMB    HLA-DRB4

    Find genes that share paralogs with IGLL5           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for IGLL5
    PGOHUM00000246316


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for IGLL5 (see all 715)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1834373031,2
    --23227973(+) TAAAAA/TGTAAG 2 -- us2k10--------
    rs96121601,2
    F--23227976(+) aaagtA/C/Tagcct 2 -- us2k10--------
    rs1885447251,2
    --23228006(+) TGGCAC/GAAGAT 2 -- us2k10--------
    rs1460871261,2
    --23228008(+) GCAGAA/GGATAC 2 -- us2k10--------
    rs1927359911,2
    --23228019(+) AAGACC/TCCTGG 2 -- us2k10--------
    rs1839179621,2
    --23228054(+) TTTCAC/TAGCAA 2 -- us2k10--------
    rs1388923431,2
    --23228062(+) CAATAA/GCAGTT 2 -- us2k10--------
    rs1867436401,2
    --23228076(+) AAGGTA/GTCAGC 2 -- us2k10--------
    rs1149624711,2
    --23228110(+) GGTGAC/TGCAAA 2 -- us2k10--------
    rs1912576781,2
    --23228112(+) TGATGC/TAAAGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for IGLL5 (23229960 - 23238287 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IGLL5 (see all 47):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662193CNV Deletion23128226
    nsv820655CNV Deletion20802225
    esv2658780CNV Deletion23128226
    dgv822e199CNV Deletion23128226
    nsv3572CNV Insertion18451855
    nsv508728CNV Insertion20534489
    nsv829059CNV Loss20364138
    nsv433178CNV Loss18776910
    dgv733n67CNV Loss20364138
    dgv551n27CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing IGLL5
    DNA2.0 Custom Variant and Variant Library Synthesis for IGLL5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for IGLL5:    
    About MalaCards
    carotid artery dissection

    1 disease from the University of Copenhagen DISEASES database for IGLL5:
    Carotid artery dissection

    Find genes that share disorders with IGLL5           About GenesLikeMe


    Export disorders for IGLL5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for IGLL5 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with IGLL5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure of the human Ig lambda 1 gene suggests that it may be expressed as an Ig lambda 14.1-like protein or as a canonical B cell Ig lambda light chain: implications for Ig lambda gene evolution. (PubMed id 1703205)1, 2 Evans R.J. and Hollis G.F. (J. Exp. Med. 1991)
    2. Expression of a novel type of immunoglobulin C lambda transcripts in human mature B lymphocytes producing kappa light chains. (PubMed id 1900243)1, 2 Guglielmi P. and Davi F. (Eur. J. Immunol. 1991)
    3. Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry. (PubMed id 23750785)1 Moussavi-Harami S.F....Beebe D.J. (J. Proteome Res. 2013)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. The DNA sequence of human chromosome 22. (PubMed id 10591208)2 Dunham I.... Wright H. (Nature 1999)
    6. Organization and expression of the lambda-like genes that contribute to the mu-psi light chain complex in human pre-B cells. (PubMed id 1760403)1 Bossy D....Schiff C. (Int. Immunol. 1991)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 100423062 HGNC: 38476 Ensembl:ENSG00000254709 euGenes: HUgn100423062 ECgene: IGLL5
    H-InvDB: IGLL5

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for IGLL5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for IGLL5 gene:
    Search GeneIP for patents involving IGLL5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   Browse OriGene RNAi products  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for IGLL5  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for IGLL5  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for IGLL5   OriGene Custom Protein Services for IGLL5  

     
     
     Block miRNA regulation of human, mouse, rat IGLL5 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing IGLL5
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IGLL5 Predesigned siRNA for gene silencing in human, mouse, rat IGLL5
     QuantiFast Probe-based Assays in human, mouse, rat IGLL5 QuantiTect SYBR Green Assays in human, mouse, rat IGLL5
     Custom PCR Arrays for IGLL5 Search Chromatin IP Primers for IGLL5
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IGLL5  Search GeneGlobe Interaction Network for IGLL5
     Search Regulatory tfbs for IGLL5
     GenScript Custom Purified and Recombinant Proteins Services for IGLL5 GenScript cDNA clones with any tag delivered in your preferred vector for IGLL5
     GenScript Custom Assay Services for IGLL5 GenScript Custom overexpressing Cell Line Services for IGLL5
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for IGLL5
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     IGLL5 antibodies
     Search for Antibodies for IGLL5 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for IGLL5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for IGLL5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IGLL5
     Browse SwitchGear 3'UTR luciferase reporter plasmids for IGLL5
     Browse SwitchGear Promoter luciferase reporter plasmids for IGLL5
     Search ThermoFisher Antibodies for IGLL5
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLL5
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IGLL5
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IGLL5
     LSBio Antibodies in human, mouse, rat for IGLL5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for IGLL5
      Search eBioscience for proteins for IGLL5
      Search eBioscience for elisas for IGLL5
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      IGLL5 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4