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Aliases for IGLJ@ Gene

Aliases for IGLJ@ Gene

  • Immunoglobulin Lambda Joining Cluster 3
  • Immunoglobulin Lambda Joining Group 3
  • J Region Of Lambda Light Chains 3
  • IGLJ 3

External Ids for IGLJ@ Gene

Summaries for IGLJ@ Gene

Entrez Gene Summary for IGLJ@ Gene

  • Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains (see MIM 147100) and 2 identical light chains, either kappa (see MIM 147200) or lambda, joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. The kappa and lambda light chains have no apparent functional differences. Each Ig lambda light chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by a C region gene (IGLC1; MIM 147220), that provides signaling functions. The lambda light chain V region is encoded by 2 types of genes: V genes (see MIM 147240) and joining (J) genes. Random selection of just 1 gene of each type to assemble a V region accounts for the great diversity of V regions among Ig molecules. The lambda light chain locus on chromosome 22 contains approximately 30 functional V genes, followed by approximately 4 functional J genes. Due to polymorphism, the numbers of functional V and J genes differ among individuals (Janeway et al., 2005).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGLJ@ Gene

IGLJ@ (Immunoglobulin Lambda Joining Cluster) is a Gene Cluster. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and Immune response NFAT in immune response.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLJ@ Gene

Genomics for IGLJ@ Gene

Genomic Location for IGLJ@ Gene

Unknown strand

Genomic View for IGLJ@ Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for IGLJ@ Gene

Proteins for IGLJ@ Gene

Post-translational modifications for IGLJ@ Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGLJ@ Gene

Domains for IGLJ@ Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGLJ@ Gene

Function for IGLJ@ Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLJ@ Gene

Localization for IGLJ@ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGLJ@ Gene

Expression for IGLJ@ Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for IGLJ@ Gene

Orthologs for IGLJ@ Gene

No data available for Orthologs and Evolution for IGLJ@ Gene

Paralogs for IGLJ@ Gene

No data available for Paralogs for IGLJ@ Gene

Variants for IGLJ@ Gene

Relevant External Links for IGLJ@ Gene

Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGLJ@ Gene

Disorders for IGLJ@ Gene

No disorders were found for IGLJ@ Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for IGLJ@ Gene

Publications for IGLJ@ Gene

No publications were found for IGLJ@ Gene.

Products for IGLJ@ Gene

Sources for IGLJ@ Gene

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